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Conserved domains on  [gi|28557777|ref|NP_787120|]
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immunoglobulin-like domain-containing receptor 1 isoform 2 precursor [Homo sapiens]

Protein Classification

immunoglobulin domain-containing family protein( domain architecture ID 34076)

immunoglobulin (Ig) domain-containing family protein is a member of a large superfamily containing cell surface antigen receptors, co-receptors and co-stimulatory molecules of the immune system, molecules involved in antigen presentation to lymphocytes, cell adhesion molecules, certain cytokine receptors and intracellular muscle proteins; immunoglobulin domains are typically divided into 4 main classes based on their structures and sequences: the Variable (V), Constant 1 (C1), Constant 2 (C2), and Intermediate (I) sets

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
V-set super family cl46292
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 31-166 5.40e-04

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


The actual alignment was detected with superfamily member pfam07686:

Pssm-ID: 462230  Cd Length: 109  Bit Score: 39.75  E-value: 5.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28557777    31 TERYVT--LFASIILKCDYTTSAQLQDVVVTWrfksfCKDPifdyysasyqaalslgqdpsndcNDNQREVRIVAQRRGQ 108
Cdd:pfam07686   2 TPREVTvaLGGSVTLPCTYSSSMSEASTSVYW-----YRQP-----------------------PGKGPTFLIAYYSNGS 53

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28557777   109 NEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIeaPGDTSGDPDKEVKLIVL 166
Cdd:pfam07686  54 EEGVKKGRFSGRGDPSNGDGSLTIQNLTLSDSGTYTCAV--IPSGEGVFGKGTRLTVL 109
 
Name Accession Description Interval E-value
V-set pfam07686
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 31-166 5.40e-04

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


Pssm-ID: 462230  Cd Length: 109  Bit Score: 39.75  E-value: 5.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28557777    31 TERYVT--LFASIILKCDYTTSAQLQDVVVTWrfksfCKDPifdyysasyqaalslgqdpsndcNDNQREVRIVAQRRGQ 108
Cdd:pfam07686   2 TPREVTvaLGGSVTLPCTYSSSMSEASTSVYW-----YRQP-----------------------PGKGPTFLIAYYSNGS 53

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28557777   109 NEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIeaPGDTSGDPDKEVKLIVL 166
Cdd:pfam07686  54 EEGVKKGRFSGRGDPSNGDGSLTIQNLTLSDSGTYTCAV--IPSGEGVFGKGTRLTVL 109
 
Name Accession Description Interval E-value
V-set pfam07686
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 31-166 5.40e-04

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


Pssm-ID: 462230  Cd Length: 109  Bit Score: 39.75  E-value: 5.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28557777    31 TERYVT--LFASIILKCDYTTSAQLQDVVVTWrfksfCKDPifdyysasyqaalslgqdpsndcNDNQREVRIVAQRRGQ 108
Cdd:pfam07686   2 TPREVTvaLGGSVTLPCTYSSSMSEASTSVYW-----YRQP-----------------------PGKGPTFLIAYYSNGS 53

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28557777   109 NEPVLGVDYRQRKITIQNRADLVINEVMWWDHGVYYCTIeaPGDTSGDPDKEVKLIVL 166
Cdd:pfam07686  54 EEGVKKGRFSGRGDPSNGDGSLTIQNLTLSDSGTYTCAV--IPSGEGVFGKGTRLTVL 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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