|
Name |
Accession |
Description |
Interval |
E-value |
| DUF3668 |
pfam12416 |
Cep120 protein; This family includes the Cep120 protein which is associated with centriole ... |
118-340 |
1.05e-126 |
|
Cep120 protein; This family includes the Cep120 protein which is associated with centriole structure and function.
Pssm-ID: 463569 Cd Length: 226 Bit Score: 383.21 E-value: 1.05e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 118 KYTKFKSEIQISIALETDTKPP---VDSFKAKGAPPRDGKVPAILAGLDPRDIVAVLNEEGGYHQIGPAEYCTDSFIMSV 194
Cdd:pfam12416 1 KYTKQKPELLLSLALEKDSKPHtkdFDSFKAKPAPPRQSPGHSILANLLPSKLIPYLNEEEGYHQIGPADLCCDIFVLSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 195 TIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFNDLINPNFEPERASVRIRSSVEILRVYLALQSKLQIHLC 274
Cdd:pfam12416 81 TIAFATNLEQLVPSSMKLPEEKPGFFFYYSLLGNDVTNEPFKNLLNPNFEPERASVRIRSSLRVLRAYLSSQPYLQIHLC 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 275 CGDQSLGSTEIPLTGLLKKGSTEINQHPVTVEGAFTLDPPNRAKQKLAPIPVELAPTVGVSVALQR 340
Cdd:pfam12416 161 CGNQSLGSTEVSLQGLLPDNSTELERKPVTIEGAFVLNPPNRAKQDLPEVPLELKPTVGVTVTLRR 226
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
669-923 |
1.25e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.99 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 669 ENQL----KQKELAH-MQALAEEWKKRDREReslvkkKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSE 743
Cdd:COG1196 199 ERQLepleRQAEKAErYRELKEELKELEAEL------LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 744 RQRnLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPE--IRLQSEIN 821
Cdd:COG1196 273 RLE-LEELELELEEAQA----EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEelEELEEELE 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 822 LLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELL 901
Cdd:COG1196 348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
|
250 260
....*....|....*....|..
gi 96975038 902 DIRNELNRLRQQEQKQYQDSTE 923
Cdd:COG1196 428 EALAELEEEEEEEEEALEEAAE 449
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
650-951 |
3.48e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.37 E-value: 3.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 650 EYKAALELEMWKEMQEDIfenQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASV 729
Cdd:COG1196 224 ELEAELLLLKLRELEAEL---EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 730 ESELQREKKELQsERQRNLQELQDSIRRAKEDCI-HQVELERL--KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD 806
Cdd:COG1196 301 EQDIARLEERRR-ELEERLEELEEELAELEEELEeLEEELEELeeELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 807 QQN--NKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRY 884
Cdd:COG1196 380 ELEelAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 885 LAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYqDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEE 951
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARL-LLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
718-981 |
9.67e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 9.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 718 DLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKIL 797
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 798 EKEFQQFKDQQnnkpeIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEEL 877
Cdd:COG1196 301 EQDIARLEERR-----RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 878 EQMRLRylaAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDgphgsvLEEGLDDYLTRLIEERDTLMR 957
Cdd:COG1196 376 EAEEEL---EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE------LEEALAELEEEEEEEEEALEE 446
|
250 260
....*....|....*....|....
gi 96975038 958 tgVYNHEDRIISELDRQIREILAK 981
Cdd:COG1196 447 --AAEEEAELEEEEEALLELLAEL 468
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
675-980 |
5.46e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.56 E-value: 5.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 675 KELAHMQALAEEWKKRDRERESLVKKKvaeyTILEGKLQKTLIDLEKREQQLASVESELQR--EKKELQSERQRNLQELQ 752
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSEL----RRIENRLDELSQELSDASRKIGEIEKEIEQleQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 753 DSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYkiLEKEFQQFKDQQNNKPEIRlqSEINLLTlekVELER 832
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKLEEEV--SRIEARL---REIEQ 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 833 KLEsatksKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELeQMRLRYLAAEEKDTVKTERQ---ELLDIRNELNR 909
Cdd:TIGR02169 820 KLN-----RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL-NGKKEELEEELEELEAALRDlesRLGDLKKERDE 893
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 96975038 910 ----LRQQEQKQYQDSTEIASGKKdgpHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREILA 980
Cdd:TIGR02169 894 leaqLRELERKIEELEAQIEKKRK---RLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEE 965
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
655-955 |
2.85e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.24 E-value: 2.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 655 LELEMwKEMQEDIFENQLKQKELAH-MQALAEEWKKRDRERESLVKKKVAEYTILEgKLQKTLIDLEKREQQLASVESEL 733
Cdd:TIGR02168 682 LEEKI-EELEEKIAELEKALAELRKeLEELEEELEQLRKELEELSRQISALRKDLA-RLEAEVEQLEERIAQLSKELTEL 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 734 QREKKELQSERQ----------RNLQELQDSIRRAKEDC---IHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKE 800
Cdd:TIGR02168 760 EAEIEELEERLEeaeeelaeaeAEIEELEAQIEQLKEELkalREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 801 FQQFKDQ--QNNKPEIRLQSEINLLTLEKVELERKLESATKSKlhykqqwgRALKELARLKQREQESQMARLkkQQEELE 878
Cdd:TIGR02168 840 LEDLEEQieELSEDIESLAAEIEELEELIEELESELEALLNER--------ASLEEALALLRSELEELSEEL--RELESK 909
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 879 QMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSvlEEGLDDYLTRLIEERDTL 955
Cdd:TIGR02168 910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDD--EEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
670-916 |
3.58e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.86 E-value: 3.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 670 NQLKQKELAhmqALAEEWKKRDRERESLvKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSErqrnLQ 749
Cdd:TIGR02168 220 AELRELELA---LLVLRLEELREELEEL-QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE----LY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 750 ELQDSIRRAKEDCIHQVElerlKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVE 829
Cdd:TIGR02168 292 ALANEISRLEQQKQILRE----RLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----ELKEELESLEAELEE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 830 LERKLESATKSKLHYKQQWGRALKELARLKQRE--QESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNEL 907
Cdd:TIGR02168 363 LEAELEELESRLEELEEQLETLRSKVAQLELQIasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL 442
|
....*....
gi 96975038 908 NRLRQQEQK 916
Cdd:TIGR02168 443 EELEEELEE 451
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
640-884 |
3.29e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.77 E-value: 3.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 640 EIQTEPRETLEYKAALELEMwKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDL 719
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEV-SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 720 EKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDcihQVELERL--KIKQLEEDKHRLQQQLNDAENKYKIL 797
Cdd:TIGR02168 336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL---EEQLETLrsKVAQLELQIASLNNEIERLEARLERL 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 798 EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQMARLKKQQE 875
Cdd:TIGR02168 413 EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDaaERELAQLQARLD 492
|
....*....
gi 96975038 876 ELEQMRLRY 884
Cdd:TIGR02168 493 SLERLQENL 501
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
675-974 |
3.43e-11 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 67.46 E-value: 3.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 675 KELAHMQALAEEWKKRDRERESL-----VKKKVAEYTILEGKlqKTLIDLEKREQQLASVESELQREKKELQSERQRNLQ 749
Cdd:pfam17380 221 KEVQGMPHTLAPYEKMERRKESFnlaedVTTMTPEYTVRYNG--QTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQ 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 750 ElqdSIRRAKEDCIHQVELERlkikQLEEDKHRLQQQLND-----AENKYKILEKEFQ----QFKDQQNNKPEIRlQSEI 820
Cdd:pfam17380 299 E---RLRQEKEEKAREVERRR----KLEEAEKARQAEMDRqaaiyAEQERMAMEREREleriRQEERKRELERIR-QEEI 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 821 -----NLLTLEKVELERK---------LESATKSKLhykqqwgraLKELARLKQREQESQMARLKKQQEELEQMRLRYLA 886
Cdd:pfam17380 371 ameisRMRELERLQMERQqknervrqeLEAARKVKI---------LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 887 AEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGS-----VLEEGLDDYLTRLIEE---RDTLMR- 957
Cdd:pfam17380 442 EERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEeqrrkILEKELEERKQAMIEEerkRKLLEKe 521
|
330 340
....*....|....*....|..
gi 96975038 958 -----TGVYNHEDRIISELDRQ 974
Cdd:pfam17380 522 meerqKAIYEEERRREAEEERR 543
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
709-923 |
4.82e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 4.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 709 EGKLQKTLIDLEKREQQLASVESELqrEKKELQSERQRNLQELQDSIRRAkedcihQVELERLKIKQLEEDKHRLQQQLN 788
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELERQL--KSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 789 DAENKYKILEKEFQQfkdqqnnkpeirLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQ 866
Cdd:TIGR02168 250 EAEEELEELTAELQE------------LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnlERQ 317
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 96975038 867 MARLKKQQEELEQMRLRYLA-----AEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 923
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEelaelEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
666-919 |
7.93e-11 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 66.48 E-value: 7.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 666 DIFENQLKQKElAHMQALAEEWKKRDRERESLVKKKVAEYTILEgkLQKTLIDLEKREQQLASVESELQR------EKKE 739
Cdd:COG4913 613 AALEAELAELE-EELAEAEERLEALEAELDALQERREALQRLAE--YSWDEIDVASAEREIAELEAELERldassdDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 740 LQSERQRnLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKI-----LEKEFQQFKDQQNNKpEI 814
Cdd:COG4913 690 LEEQLEE-LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLelralLEERFAAALGDAVER-EL 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 815 R--LQSEINLLTLEKVELERKLESATKSklhYKQQW--------------GRALKELARLKQR---EQESQMARLKKQQE 875
Cdd:COG4913 768 RenLEERIDALRARLNRAEEELERAMRA---FNREWpaetadldadleslPEYLALLDRLEEDglpEYEERFKELLNENS 844
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 96975038 876 ELEQMRLRYLAAEEKDTVkteRQELLDIRNELNRLRQQEQKQYQ 919
Cdd:COG4913 845 IEFVADLLSKLRRAIREI---KERIDPLNDSLKRIPFGPGRYLR 885
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
640-902 |
1.78e-10 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 63.78 E-value: 1.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYtiLEGKLQKTLIDL 719
Cdd:pfam13868 95 EKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY--LKEKAEREEERE 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 720 EKREQQLASVESELQREKKELQSERQRnlQELQDSIRRAKEDCIHQVElERLKIKQLEEDKHRLQQQLNDAENKYKILEK 799
Cdd:pfam13868 173 AEREEIEEEKEREIARLRAQQEKAQDE--KAERDELRAKLYQEEQERK-ERQKEREEAEKKARQRQELQQAREEQIELKE 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 800 EFQQFkdqqnnkpEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQwgralkELAR--LKQREQESQMARLKKQQEEL 877
Cdd:pfam13868 250 RRLAE--------EAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRL------EHRRelEKQIEEREEQRAAEREEELE 315
|
250 260
....*....|....*....|....*
gi 96975038 878 EQMRLRYLAAEEKDTVKTERQELLD 902
Cdd:pfam13868 316 EGERLREEEAERRERIEEERQKKLK 340
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
652-985 |
3.53e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 3.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 652 KAALELEmwkEMQEDIFENQLKQKELA-HMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVE 730
Cdd:TIGR02169 174 KALEELE---EVEENIERLDLIIDEKRqQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 731 SELQREKKELQ------SERQRNLQELQDSIRRAKEDCIHQV--ELERLK--IKQLEEDKHRLQQQLNDAENKYKILEKE 800
Cdd:TIGR02169 251 EELEKLTEEISelekrlEEIEQLLEELNKKIKDLGEEEQLRVkeKIGELEaeIASLERSIAEKERELEDAEERLAKLEAE 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 801 FQQFKDQ---------QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKqREQESQMARLK 871
Cdd:TIGR02169 331 IDKLLAEieelereieEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK-REINELKRELD 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 872 KQQEELEQMrlrylaaeekdtvkteRQELLDIRNELNRLRQQeQKQYQDSTE--IASGKKDGPHGSVLEEGLDDYLTRLI 949
Cdd:TIGR02169 410 RLQEELQRL----------------SEELADLNAAIAGIEAK-INELEEEKEdkALEIKKQEWKLEQLAADLSKYEQELY 472
|
330 340 350
....*....|....*....|....*....|....*.
gi 96975038 950 EERDTLMRTgvynhEDRiISELDRQIREILAKSNAS 985
Cdd:TIGR02169 473 DLKEEYDRV-----EKE-LSKLQRELAEAEAQARAS 502
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
739-986 |
9.01e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.70 E-value: 9.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 739 ELQSERQRNLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ--QNNKPEIRL 816
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEK----ELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 817 QSEINLLtleKVELERKLESATKSKLHYK-------QQWGRALKELARLKQ--REQESQMARLKKQQEELEQmrLRYLAA 887
Cdd:COG4942 96 RAELEAQ---KEELAELLRALYRLGRQPPlalllspEDFLDAVRRLQYLKYlaPARREQAEELRADLAELAA--LRAELE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 888 EEKDTVKTERQELLDIRNELNRLRQQEQKQyqdsteIASGKKDgphgsvlEEGLDDYLTRLIEERDTLmrtgvynheDRI 967
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKL------LARLEKE-------LAELAAELAELQQEAEEL---------EAL 228
|
250
....*....|....*....
gi 96975038 968 ISELDRQIREILAKSNASN 986
Cdd:COG4942 229 IARLEAEAAAAAERTPAAG 247
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
670-986 |
9.81e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.85 E-value: 9.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 670 NQLKQKELAHMQA----LAEEWKKRDRERESLVKKKVAEYTILEgklQKTLIDLEKREQQLASVESELQREKKELQSERQ 745
Cdd:PTZ00121 1500 DEAKKAAEAKKKAdeakKAEEAKKADEAKKAEEAKKADEAKKAE---EKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 746 RNLQELQDSIRRAKEDCIHQV-----ELERLKIKQL--EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQS 818
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEARIEEVmklyeEEKKMKAEEAkkAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE 1656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 819 EINllTLEKVELERKLESATKSKlhykqqwgralkELARLKQREQESQMARLKKQQEELEQM-RLRYLAAEEK---DTVK 894
Cdd:PTZ00121 1657 EEN--KIKAAEEAKKAEEDKKKA------------EEAKKAEEDEKKAAEALKKEAEEAKKAeELKKKEAEEKkkaEELK 1722
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 895 TERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRlieERDTLMRTGVYNHEDRIISELDRQ 974
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRK---EKEAVIEEELDEEDEKRRMEVDKK 1799
|
330
....*....|..
gi 96975038 975 IREIlaKSNASN 986
Cdd:PTZ00121 1800 IKDI--FDNFAN 1809
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
660-912 |
1.31e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.39 E-value: 1.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 660 WKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERE---SLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQRE 736
Cdd:PRK03918 164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEkelEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEEL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 737 KKELQSERQrNLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAEnKYKILEKEFQQFKDQQNN--KPEI 814
Cdd:PRK03918 244 EKELESLEG-SKRKLEEKIRELEE----RIEELKKEIEELEEKVKELKELKEKAE-EYIKLSEFYEEYLDELREieKRLS 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 815 RLQSEINLLTLEKVELERKLESATKSKLHYKQqwgrALKELARLKQREQESQMARLKKqqEELEQMRLRyLAAEEKDTVK 894
Cdd:PRK03918 318 RLEEEINGIEERIKELEEKEERLEELKKKLKE----LEKRLEELEERHELYEEAKAKK--EELERLKKR-LTGLTPEKLE 390
|
250 260
....*....|....*....|..
gi 96975038 895 TERQEL----LDIRNELNRLRQ 912
Cdd:PRK03918 391 KELEELekakEEIEEEISKITA 412
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
730-917 |
1.63e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.71 E-value: 1.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 730 ESELQREKKELQSERQRNLQELQDSIRRAKEDcIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQN 809
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEE-LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 810 NKPEI----RLQSEINLLTLEKVELERKLE---SATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRL 882
Cdd:COG4717 127 LLPLYqeleALEAELAELPERLEELEERLEelrELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206
|
170 180 190
....*....|....*....|....*....|....*
gi 96975038 883 RYLAAEEKdtVKTERQELLDIRNELNRLRQQEQKQ 917
Cdd:COG4717 207 RLAELEEE--LEEAQEELEELEEELEQLENELEAA 239
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
660-913 |
2.16e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.62 E-value: 2.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 660 WKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKR----------------- 722
Cdd:TIGR02169 725 IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsripeiqaelskle 804
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 723 ------EQQLASVESELQR---EKKELQSERQrNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENK 793
Cdd:TIGR02169 805 eevsriEARLREIEQKLNRltlEKEYLEKEIQ-ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 794 YKILEKEFQQFKDQQNNkpeirLQSEINLLTLEkVELERKLESATKSKLHYKQQwgrALKELARLKQREQES-------- 865
Cdd:TIGR02169 884 LGDLKKERDELEAQLRE-----LERKIEELEAQ-IEKKRKRLSELKAKLEALEE---ELSEIEDPKGEDEEIpeeelsle 954
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 96975038 866 --QMARLKKQQ-------------EELEQMRLRYLAAEEK-DTVKTERQELLDIRNELNRLRQQ 913
Cdd:TIGR02169 955 dvQAELQRVEEeiralepvnmlaiQEYEEVLKRLDELKEKrAKLEEERKAILERIEEYEKKKRE 1018
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
639-914 |
2.22e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.53 E-value: 2.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEwkKRDRERESLVKKKVAEYTILEGKLQKTLID 718
Cdd:pfam02463 732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE--REKTEKLKVEEEKEEKLKAQEEELRALEEE 809
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 719 LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ-----VELERLKIKQLEEDKHRLQQQLNDAENK 793
Cdd:pfam02463 810 LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELerleeEITKEELLQELLLKEEELEEQKLKDELE 889
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 794 YKIL----EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHykqqwGRALKELARLKQREQESQMAR 869
Cdd:pfam02463 890 SKEEkekeEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLE-----EADEKEKEENNKEEEEERNKR 964
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 96975038 870 LKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQE 914
Cdd:pfam02463 965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIR 1009
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
713-894 |
2.54e-09 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 58.78 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 713 QKTLIDLEKREQQLASVESELQREKKELQsERQRNLQELQDSIRRAKEDcIHQVELER----LKIKQLEEDKHRLQQQLN 788
Cdd:COG1579 6 LRALLDLQELDSELDRLEHRLKELPAELA-ELEDELAALEARLEAAKTE-LEDLEKEIkrleLEIEEVEARIKKYEEQLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 789 DAENkykilEKEFQQfkdqqnnkpeirLQSEINLLTLEKVELE-------RKLESATKSKLHYKQQWGRALKELARLKQr 861
Cdd:COG1579 84 NVRN-----NKEYEA------------LQKEIESLKRRISDLEdeilelmERIEELEEELAELEAELAELEAELEEKKA- 145
|
170 180 190
....*....|....*....|....*....|...
gi 96975038 862 EQESQMARLKKQQEELEQMRLRYLAAEEKDTVK 894
Cdd:COG1579 146 ELDEELAELEAELEELEAEREELAAKIPPELLA 178
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
690-978 |
3.95e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 60.70 E-value: 3.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 690 RDRERESLV-----KKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQ-----SERQRNLQELQDSIRRAK 759
Cdd:COG4913 595 RRRIRSRYVlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeySWDEIDVASAEREIAELE 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 760 EdcihqvELERLK--IKQLEEdkhrLQQQLNDAENKYKILEKEFQQFKDQQnnkpeIRLQSEINLLTLEKVELERKLESA 837
Cdd:COG4913 675 A------ELERLDasSDDLAA----LEEQLEELEAELEELEEELDELKGEI-----GRLEKELEQAEEELDELQDRLEAA 739
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 838 TKSKLHYKQQwgRALKELARLKQREQESQMAR-LKKQQEELEQMRLRylaaeekdtvkterqelldIRNELNRLRQQEQK 916
Cdd:COG4913 740 EDLARLELRA--LLEERFAAALGDAVERELREnLEERIDALRARLNR-------------------AEEELERAMRAFNR 798
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 96975038 917 QYQDST-EIASGKKDGP-----HGSVLEEGLDDYLTRLIEERDTLMRTGVynheDRIISELDRQIREI 978
Cdd:COG4913 799 EWPAETaDLDADLESLPeylalLDRLEEDGLPEYEERFKELLNENSIEFV----ADLLSKLRRAIREI 862
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
644-954 |
4.65e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.93 E-value: 4.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 644 EPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKRE 723
Cdd:PTZ00121 1514 EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 724 QQLAsveSELQREKKELQSERQRNLQElqdsiRRAKEDCIHQVELERLKIKQL---EEDKHRLQQQLNDAENKYKILEKE 800
Cdd:PTZ00121 1594 IEEV---MKLYEEEKKMKAEEAKKAEE-----AKIKAEELKKAEEEKKKVEQLkkkEAEEKKKAEELKKAEEENKIKAAE 1665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 801 FQQFKDQQNNKPEIRLQSEinlltlekvELERKLESATKSKLHYKqqwgRALKELArlKQREQESQMARLKKQQEELEQM 880
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAE---------EDEKKAAEALKKEAEEA----KKAEELK--KKEAEEKKKAEELKKAEEENKI 1730
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 881 RLRYLAAEEKDTvKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKdgphgSVLEEGLD--DYLTRLIEERDT 954
Cdd:PTZ00121 1731 KAEEAKKEAEED-KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE-----AVIEEELDeeDEKRRMEVDKKI 1800
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
691-915 |
7.96e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.40 E-value: 7.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 691 DRERESLVKKKVAEYTILEGKLQktliDLEKREQQLASVESELQREKKELQSERQRnLQELQDSIRRAKEDcihQVELER 770
Cdd:COG4717 52 EKEADELFKPQGRKPELNLKELK----ELEEELKEAEEKEEEYAELQEELEELEEE-LEELEAELEELREE---LEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 771 LK-IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEinlltlekvELERKLESA-TKSKLHYKQQW 848
Cdd:COG4717 124 LLqLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELA---------ELQEELEELlEQLSLATEEEL 194
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 849 GRALKELARLKQREQESQmARLKKQQEELEQMRlrylaaeekdtvkterQELLDIRNELNRLRQQEQ 915
Cdd:COG4717 195 QDLAEELEELQQRLAELE-EELEEAQEELEELE----------------EELEQLENELEAAALEER 244
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
698-981 |
2.56e-08 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 57.22 E-value: 2.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 698 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQsERQRNLQELQDSIRRAKEDCIHQVElerlKIKQLE 777
Cdd:COG4372 33 LRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELE-QLEEELEELNEQLQAAQAELAQAQE----ELESLQ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 778 EDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESAtksklhykqqwgraLKELAR 857
Cdd:COG4372 108 EEAEELQEELEELQKERQDLEQQRKQLEAQIA-----ELQSEIAEREEELKELEEQLESL--------------QEELAA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 858 LKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVL 937
Cdd:COG4372 169 LEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 96975038 938 EEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREILAK 981
Cdd:COG4372 249 EELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAA 292
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
658-917 |
3.50e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.77 E-value: 3.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 658 EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKvAEYTILEGKLQKTLIDLEKREQQLASVESELqREK 737
Cdd:PRK03918 266 ERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-REIEKRLSRLEEEINGIEERIKELEEKEERL-EEL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 738 KELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQ 817
Cdd:PRK03918 344 KKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 818 SEINLLTLEKVELE-----RKLESATKSKL--HYKQQWGRALKELARLKQREQEsqmarLKKQQEELEQMRLRylaAEEK 890
Cdd:PRK03918 424 LKKAIEELKKAKGKcpvcgRELTEEHRKELleEYTAELKRIEKELKEIEEKERK-----LRKELRELEKVLKK---ESEL 495
|
250 260
....*....|....*....|....*..
gi 96975038 891 DTVKTERQELLDIRNELNRLRQQEQKQ 917
Cdd:PRK03918 496 IKLKELAEQLKELEEKLKKYNLEELEK 522
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
681-923 |
3.60e-08 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 57.18 E-value: 3.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 681 QALAEEWKKRDRER-----ESLVKKKVAEYTILEGKL----QKTLIDLEKRE--QQLASVESELQREKKELQSERQRNLQ 749
Cdd:pfam02029 62 EAFLDRTAKREERRqkrlqEALERQKEFDPTIADEKEsvaeRKENNEEEENSswEKEEKRDSRLGRYKEEETEIREKEYQ 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 750 E--LQDSIRRAKEDCIHQvELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEK 827
Cdd:pfam02029 142 EnkWSTEVRQAEEEGEEE-EDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLK 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 828 VELERKleSATKSKLHYKQQWGRALKE----LARLKQREQEsqmarlkKQQEELEQMRLRYLAAE-EKDTVKTERQELLD 902
Cdd:pfam02029 221 VTTKRR--QGGLSQSQEREEEAEVFLEaeqkLEELRRRRQE-------KESEEFEKLRQKQQEAElELEELKKKREERRK 291
|
250 260
....*....|....*....|.
gi 96975038 903 IRNELNRLRQQEQKQYQDSTE 923
Cdd:pfam02029 292 LLEEEEQRRKQEEAERKLREE 312
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
663-901 |
5.41e-08 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 56.44 E-value: 5.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 663 MQEDIFENQLKQKELAHMQALAEEWKKRDRERESlvkkKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQS 742
Cdd:pfam07888 47 LQAQEAANRQREKEKERYKRDREQWERQRRELES----RVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 743 ERQRNLQ---ELQDSIRRAKEDCI-HQVELERLK---------IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQN 809
Cdd:pfam07888 123 QRAAHEArirELEEDIKTLTQRVLeRETELERMKerakkagaqRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLA 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 810 NKPE--IRLQSEINLLTL-------EKVELERKLE--SATKSKLHYKQQ----WGRALKELARLKQREQ-ESQMARLKKQ 873
Cdd:pfam07888 203 QRDTqvLQLQDTITTLTQklttahrKEAENEALLEelRSLQERLNASERkvegLGEELSSMAAQRDRTQaELHQARLQAA 282
|
250 260
....*....|....*....|....*...
gi 96975038 874 QEELEQMRLRYLAAEEKDTVKTERQELL 901
Cdd:pfam07888 283 QLTLQLADASLALREGRARWAQERETLQ 310
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
656-900 |
8.58e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 56.28 E-value: 8.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 656 ELEMWKEMQEDIFENQLKQKELAHMQaLAEEWKKRDREREslvkkkvaEYTILEGKLQKTLIDLEKREQQLaSVESELQR 735
Cdd:pfam15921 332 ELREAKRMYEDKIEELEKQLVLANSE-LTEARTERDQFSQ--------ESGNLDDQLQKLLADLHKREKEL-SLEKEQNK 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 736 E---------------KKELqSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKE 800
Cdd:pfam15921 402 RlwdrdtgnsitidhlRREL-DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKV 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 801 FQQFKDQQnnkpeIRLQSE---INLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQEsqmarLKKQQEEL 877
Cdd:pfam15921 481 VEELTAKK-----MTLESSertVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDH-----LRNVQTEC 550
|
250 260
....*....|....*....|...
gi 96975038 878 EQMRLRylAAEEKDTVKTERQEL 900
Cdd:pfam15921 551 EALKLQ--MAEKDKVIEILRQQI 571
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
702-926 |
1.48e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.69 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 702 VAEYTILEGkLQKTLIDLEKREQQLASVEsELQREKKELQseRQRNLQELQDSIRRAKEDcIHQVELERLKIKQLEEDKH 781
Cdd:COG4913 231 VEHFDDLER-AHEALEDAREQIELLEPIR-ELAERYAAAR--ERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 782 RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQseinlltlekvELERKLESATKSKLHYKQQWGRALKELARLKQR 861
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRGNGGDRLE-----------QLEREIERLERELEERERRRARLEALLAALGLP 374
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 862 EQESQmarlkkqqEELEQMRLRylAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD-STEIAS 926
Cdd:COG4913 375 LPASA--------EEFAALRAE--AAALLEALEEELEALEEALAEAEAALRDLRRELRElEAEIAS 430
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
673-840 |
1.61e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 53.39 E-value: 1.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 673 KQKELAHMQALAEEWKKRDRERESLvKKKVAEytiLEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQR--NLQE 750
Cdd:COG1579 5 DLRALLDLQELDSELDRLEHRLKEL-PAELAE---LEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARikKYEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 751 LQDSIRRAKE--DCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKpEIRLQSEINLLTLEKV 828
Cdd:COG1579 81 QLGNVRNNKEyeALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEK-KAELDEELAELEAELE 159
|
170
....*....|..
gi 96975038 829 ELERKLESATKS 840
Cdd:COG1579 160 ELEAEREELAAK 171
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
718-880 |
2.83e-07 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 54.26 E-value: 2.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 718 DLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDcIHQVELER----LKIKQLEEDKHRLQQQLNDAENK 793
Cdd:pfam05667 307 QFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESS-IQELEKEIkkleSSIKQVEEELEELKEQNEELEKQ 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 794 YKILEKEFQQFKDQQNNkpeirlqseinlltLEKveLERKLESATKSKLHYKQQWG----------RALKELARLKQREQ 863
Cdd:pfam05667 386 YKVKKKTLDLLPDAEEN--------------IAK--LQALVDASAQRLVELAGQWEkhrvplieeyRALKEAKSNKEDES 449
|
170
....*....|....*..
gi 96975038 864 ESQMARLKKQQEELEQM 880
Cdd:pfam05667 450 QRKLEEIKELREKIKEV 466
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
689-955 |
8.13e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.44 E-value: 8.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 689 KRDRERESLVKKKVAEY----TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDcIH 764
Cdd:pfam02463 168 KRKKKEALKKLIEETENlaelIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 765 QVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER----------KL 834
Cdd:pfam02463 247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEklkesekekkKA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 835 ESATKSKLHYK--QQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYL---------AAEEKDTVKTERQELLDI 903
Cdd:pfam02463 327 EKELKKEKEEIeeLEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKkleserlssAAKLKEEELELKSEEEKE 406
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 96975038 904 RNELNRLRQQEQKQYQDSTEIASGKKdgphgSVLEEGLDDYLTRLIEERDTL 955
Cdd:pfam02463 407 AQLLLELARQLEDLLKEEKKEELEIL-----EEEEESIELKQGKLTEEKEEL 453
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
661-907 |
8.48e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 53.10 E-value: 8.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 661 KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKEL 740
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 741 QSERQRNLQeLQDSIRRAKEDcIHQVElerLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKpeirlQSEI 820
Cdd:TIGR04523 429 ERLKETIIK-NNSEIKDLTNQ-DSVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-----EKEL 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 821 NLLTLEKVELERKLESATK--SKLHYKQ--------QWGRALKELAR-LKQREQESQMARLKKQ----QEELEQMRLRYL 885
Cdd:TIGR04523 499 KKLNEEKKELEEKVKDLTKkiSSLKEKIeklesekkEKESKISDLEDeLNKDDFELKKENLEKEidekNKEIEELKQTQK 578
|
250 260
....*....|....*....|....*..
gi 96975038 886 AAEEKDTVKTER-----QELLDIRNEL 907
Cdd:TIGR04523 579 SLKKKQEEKQELidqkeKEKKDLIKEI 605
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
640-808 |
1.03e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.85 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 640 EIQTEPRETLEYKAALElEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLvkkkvAEYTILEGKLQKTLIDL 719
Cdd:COG4717 85 EKEEEYAELQEELEELE-EELEELEAELEELREELEKLEKLLQLLPLYQELEALEAEL-----AELPERLEELEERLEEL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 720 EKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihqvELERL--KIKQLEEDKHRLQQQLNDAENKYKIL 797
Cdd:COG4717 159 RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE------ELEELqqRLAELEEELEEAQEELEELEEELEQL 232
|
170
....*....|.
gi 96975038 798 EKEFQQFKDQQ 808
Cdd:COG4717 233 ENELEAAALEE 243
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
642-916 |
1.10e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.67 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAE---YTILEGKL---QKT 715
Cdd:pfam02463 243 QELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLerrKVDDEEKLkesEKE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRakedcihQVELERLKIKQLeeDKHRLQQQLNDAENKYK 795
Cdd:pfam02463 323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL-------QEKLEQLEEELL--AKKKLESERLSSAAKLK 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 796 ILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKlhykqqwgraLKELARLKQREQESQMARLKKQQE 875
Cdd:pfam02463 394 EEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI----------ELKQGKLTEEKEELEKQELKLLKD 463
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 96975038 876 ELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK 916
Cdd:pfam02463 464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
669-917 |
1.42e-06 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 51.46 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 669 ENQLKQKELAHMQALAEEwKKRDRERESLVKKKVAEYTILEGKLQktlidlEKREQQLASVESELQREKKELQSERQRNL 748
Cdd:pfam13868 25 DAQIAEKKRIKAEEKEEE-RRLDEMMEEERERALEEEEEKEEERK------EERKRYRQELEEQIEEREQKRQEEYEEKL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 749 QElqdsiRRAKEDCIHQVELERLKIKQLeedKHRLQQQLNdaenkykileKEFQQFKDQQNNKPEIRLQSEinlltlekV 828
Cdd:pfam13868 98 QE-----REQMDEIVERIQEEDQAEAEE---KLEKQRQLR----------EEIDEFNEEQAEWKELEKEEE--------R 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 829 ELERKLESATKSKLHYKQQWGRALKELARLKQREQE---SQMARLKKQQEELEQMRL-RYLAAEEKDTVKTERQELLDIR 904
Cdd:pfam13868 152 EEDERILEYLKEKAEREEEREAEREEIEEEKEREIArlrAQQEKAQDEKAERDELRAkLYQEEQERKERQKEREEAEKKA 231
|
250
....*....|...
gi 96975038 905 NELNRLRQQEQKQ 917
Cdd:pfam13868 232 RQRQELQQAREEQ 244
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
723-920 |
2.03e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 51.94 E-value: 2.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 723 EQQLASVESELQREKKELQSERQRN-LQELQDsirrakedcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEkef 801
Cdd:COG3206 181 EEQLPELRKELEEAEAALEEFRQKNgLVDLSE-----------EAKLLLQQLSELESQLAEARAELAEAEARLAALR--- 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 802 QQFKDQQNNKPEIRLQSEINLLTLEKVELERKL--ESATKSKLHYK-QQWGRALKELARLKQREQESQMARLKKQQEELE 878
Cdd:COG3206 247 AQLGSGPDALPELLQSPVIQQLRAQLAELEAELaeLSARYTPNHPDvIALRAQIAALRAQLQQEAQRILASLEAELEALQ 326
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 96975038 879 QmRLRYLAAEEkDTVKTERQELLDIRNELNRLRQQ---EQKQYQD 920
Cdd:COG3206 327 A-REASLQAQL-AQLEARLAELPELEAELRRLEREvevARELYES 369
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
677-913 |
2.11e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 677 LAHMQALAEEWKKRDRERESLVKKKvAEYTILEG------KLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQE 750
Cdd:COG4913 224 FEAADALVEHFDDLERAHEALEDAR-EQIELLEPirelaeRYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 751 lqdsirrakedcihqvelerlKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQnnkpEIRLQSEINLLTLEKVEL 830
Cdd:COG4913 303 ---------------------ELARLEAELERLEARLDALREELDELEAQIRGNGGDR----LEQLEREIERLERELEER 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 831 ERKLESAtksklhykQQWGRALKELARLKQREQESQMARLKKQQEELEQMR--LRYLAAEEKDTVKTERQELLDIRNELN 908
Cdd:COG4913 358 ERRRARL--------EALLAALGLPLPASAEEFAALRAEAAALLEALEEELeaLEEALAEAEAALRDLRRELRELEAEIA 429
|
....*
gi 96975038 909 RLRQQ 913
Cdd:COG4913 430 SLERR 434
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
720-917 |
2.24e-06 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 51.49 E-value: 2.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 720 EKREQQLASVESELQREKKelQSERQRnLQELQDSIRRakedcihqVELERlKIKQLEEDKHRLQQQLNDAENKYKILEK 799
Cdd:pfam15709 313 EERSEEDPSKALLEKREQE--KASRDR-LRAERAEMRR--------LEVER-KRREQEEQRRLQQEQLERAEKMREELEL 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 800 EfqqfkdQQNNKPEIRL----QSEINLLTLEKVELERKLESATKSKLHYKQQ-WGRALKELARLKQREQESQMARLKKQQ 874
Cdd:pfam15709 381 E------QQRRFEEIRLrkqrLEEERQRQEEEERKQRLQLQAAQERARQQQEeFRRKLQELQRKKQQEEAERAEAEKQRQ 454
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 96975038 875 EEL------EQMRLRYLAAEEKDTVKTERQELLD-IRNELNRLRQQEQKQ 917
Cdd:pfam15709 455 KELemqlaeEQKRLMEMAEEERLEYQRQKQEAEEkARLEAEERRQKEEEA 504
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
646-858 |
2.90e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.48 E-value: 2.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 646 RETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 725
Cdd:COG1196 308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 726 LASVESELQREKKELQS---------ERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKI 796
Cdd:COG1196 388 LLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 96975038 797 LEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARL 858
Cdd:COG1196 468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
664-917 |
4.34e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 4.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 664 QEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSE 743
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 744 RQRNLQELQDSIRRAkedcihqvelerLKIKQLEEDKHRLQQQ-LNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINL 822
Cdd:COG4942 99 LEAQKEELAELLRAL------------YRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAE-----ELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 823 LTlekvELERKLESATKSKLHYKQQWGRALKELARLKQrEQESQMARLKKQQEELEQmRLRYLAAEEKdtvkterqellD 902
Cdd:COG4942 162 LA----ALRAELEAERAELEALLAELEEERAALEALKA-ERQKLLARLEKELAELAA-ELAELQQEAE-----------E 224
|
250
....*....|....*
gi 96975038 903 IRNELNRLRQQEQKQ 917
Cdd:COG4942 225 LEALIARLEAEAAAA 239
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
616-929 |
6.29e-06 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 49.87 E-value: 6.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 616 SDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWK---EMQEDIFENQLKQKELAHMQALAEE-WKKRD 691
Cdd:pfam02029 25 EEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDRTAKreeRRQKRLQEALERQKEFDPTIADEKEsVAERK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 692 RERESLVKKKVAEYTILEGKLQKTLID----LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVE 767
Cdd:pfam02029 105 ENNEEEENSSWEKEEKRDSRLGRYKEEeteiREKEYQENKWSTEVRQAEEEGEEEEDKSEEAEEVPTENFAKEEVKDEKI 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 768 LERLKIKqlEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQS-EINLLTLEKVELERKLESATKS------ 840
Cdd:pfam02029 185 KKEKKVK--YESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLSQSqEREEEAEVFLEAEQKLEELRRRrqekes 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 841 ----KLHYKQQwgRALKELARLKQREQESQMARlkkqqEELEQMRlrylAAEEKDTVKTERQELLDIRNELNRLRQQ--E 914
Cdd:pfam02029 263 eefeKLRQKQQ--EAELELEELKKKREERRKLL-----EEEEQRR----KQEEAERKLREEEEKRRMKEEIERRRAEaaE 331
|
330
....*....|....*
gi 96975038 915 QKQYQDSTEIASGKK 929
Cdd:pfam02029 332 KRQKLPEDSSSEGKK 346
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
644-939 |
7.71e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 7.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 644 EPRETLEYKAALELEMWKEMQEdifENQLKQKelAHMQALAEEWKKRDREreslvKKKVAEYTILEGKLQKTLIDLEKRE 723
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKK---ADEAKKK--AEEAKKADEAKKKAEE-----AKKKADAAKKKAEEAKKAAEAAKAE 1351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 724 QQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELErlkiKQLEEDKHRLQQQLNDAENKYKilekefqq 803
Cdd:PTZ00121 1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK----KKAEEDKKKADELKKAAAAKKK-------- 1419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 804 fKDQQNNKPEIRLQSEinlltlekvELERKLESATKS-KLHYKQQWGRALKELArlKQREQESQMARLKKQQEELEQMRL 882
Cdd:PTZ00121 1420 -ADEAKKKAEEKKKAD---------EAKKKAEEAKKAdEAKKKAEEAKKAEEAK--KKAEEAKKADEAKKKAEEAKKADE 1487
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE 939
Cdd:PTZ00121 1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE 1544
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
669-795 |
8.56e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.39 E-value: 8.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 669 ENQLKQKELahmQAlAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELqSERQRNL 748
Cdd:PRK12704 52 EAIKKEALL---EA-KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKEL-EQKQQEL 126
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 96975038 749 QELQDSIRRAKEDciHQVELERLKIKQLEEDKHRLqqqLNDAENKYK 795
Cdd:PRK12704 127 EKKEEELEELIEE--QLQELERISGLTAEEAKEIL---LEKVEEEAR 168
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
643-971 |
9.95e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 49.72 E-value: 9.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 643 TEPRETLEYKAALELEMwKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKR 722
Cdd:pfam05483 391 SELEEMTKFKNNKEVEL-EELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHY 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 723 EQQLASVESELQREK----------KELQSERQRNLQELQD---SIRRAKEDCIHQVELERLKIKQLEEdkhrLQQQLND 789
Cdd:pfam05483 470 LKEVEDLKTELEKEKlknieltahcDKLLLENKELTQEASDmtlELKKHQEDIINCKKQEERMLKQIEN----LEEKEMN 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 790 AENKYKILEKEFQQFKDQ--------QNNKPEIR---LQSEINLLTLEKV--ELERKLESATKSkLHYKQQWGRALKELA 856
Cdd:pfam05483 546 LRDELESVREEFIQKGDEvkckldksEENARSIEyevLKKEKQMKILENKcnNLKKQIENKNKN-IEELHQENKALKKKG 624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 857 RLKQREQESQMARLKKQQEELEQMRLRYlaAEEKDTVKTE------RQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
Cdd:pfam05483 625 SAENKQLNAYEIKVNKLELELASAKQKF--EEIIDNYQKEiedkkiSEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKI 702
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 96975038 931 GPHGSVLEEGLDDYlTRLIEERDTLMrtGVYNHEDRIISEL 971
Cdd:pfam05483 703 AEMVALMEKHKHQY-DKIIEERDSEL--GLYKNKEQEQSSA 740
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
711-929 |
1.08e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.06 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 711 KLQKTLIDLEKREQQLASVESELQREKKELQSErqrnLQELQDSIRRAKEdcihqvelerlKIKQLEEDKHRLQQQLNDA 790
Cdd:COG3883 20 AKQKELSELQAELEAAQAELDALQAELEELNEE----YNELQAELEALQA-----------EIDKLQAEIAEAEAEIEER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 791 ENKYKilekefQQFKDQQNNKpeiRLQSEINLLT--------LEKVELERKLESATKSKLhyKQQwgRALKELARLKQRE 862
Cdd:COG3883 85 REELG------ERARALYRSG---GSVSYLDVLLgsesfsdfLDRLSALSKIADADADLL--EEL--KADKAELEAKKAE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 863 QESQMARLKKQQEELEQMRlrylaaEEKDTVKTERQELldirneLNRLRQQEQKQYQDSTEIASGKK 929
Cdd:COG3883 152 LEAKLAELEALKAELEAAK------AELEAQQAEQEAL------LAQLSAEEAAAEAQLAELEAELA 206
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
725-902 |
1.25e-05 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 46.85 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 725 QLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK---HR----LQQQLNDAENKYKIL 797
Cdd:pfam08614 11 RLLDRTALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELaelYRsrgeLAQRLVDLNEELQEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 798 EKEFQQfkdqqnnkpeirLQSEINLLTLEKVELERKLESATksklhykqqwgRALKELARLKQReqesqmarlkkQQEEL 877
Cdd:pfam08614 91 EKKLRE------------DERRLAALEAERAQLEEKLKDRE-----------EELREKRKLNQD-----------LQDEL 136
|
170 180
....*....|....*....|....*.
gi 96975038 878 EQMRLRYLAAEEK-DTVKTERQELLD 902
Cdd:pfam08614 137 VALQLQLNMAEEKlRKLEKENRELVE 162
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
669-909 |
1.43e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 48.97 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 669 ENQLKQKELAHMQALAEewkkrdRERESLVKKKVAEYTILEGK-LQKTLIDLEKRE---QQLASVESELQREKKELQSER 744
Cdd:pfam05557 15 QNEKKQMELEHKRARIE------LEKKASALKRQLDRESDRNQeLQKRIRLLEKREaeaEEALREQAELNRLKKKYLEAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 745 QRNLQELQDSIRRAKE--DCI--------HQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQ--NNKP 812
Cdd:pfam05557 89 NKKLNEKESQLADAREviSCLknelselrRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQssLAEA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 813 EIRLQseinlltlekvELERKLESATKSKLHYKQqwgrALKELARLKQREQEsqmarLKKQQEELEQMRlrylaaEEKDT 892
Cdd:pfam05557 169 EQRIK-----------ELEFEIQSQEQDSEIVKN----SKSELARIPELEKE-----LERLREHNKHLN------ENIEN 222
|
250
....*....|....*..
gi 96975038 893 VKTERQELLDIRNELNR 909
Cdd:pfam05557 223 KLLLKEEVEDLKRKLER 239
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
606-954 |
1.77e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 606 GLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDI-----FENQLKQKELAHM 680
Cdd:TIGR00606 730 GLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtimerFQMELKDVERKIA 809
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 681 QALAE-----------EWKKRDRERESLVKKKVAEYTILegklQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQ 749
Cdd:TIGR00606 810 QQAAKlqgsdldrtvqQVNQEKQEKQHELDTVVSKIELN----RKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ 885
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 750 ELQDSIRRAKE--DCIHQVELERLKIKQLEEDKHRLQQQ----LNDAENKYKILEKEFQQFKDQ---------------Q 808
Cdd:TIGR00606 886 FEEQLVELSTEvqSLIREIKDAKEQDSPLETFLEKDQQEkeelISSKETSNKKAQDKVNDIKEKvknihgymkdienkiQ 965
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 809 NNKPEIRLQSEINLLTLEKvelerKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQMARLKKQQE--ELEQMRLRY 884
Cdd:TIGR00606 966 DGKDDYLKQKETELNTVNA-----QLEECEKHQEKINEDMRLMRQDIDTQKIQERwlQDNLTLRKRENElkEVEEELKQH 1040
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 885 LAAEEKDTVKTERQELLDIRNELNRLRQQE------QKQYQDSTEIASGKKDGPHGSVLEEgldDYLTRLIEERDT 954
Cdd:TIGR00606 1041 LKEMGQMQVLQMKQEHQKLEENIDLIKRNHvlalgrQKGYEKEIKHFKKELREPQFRDAEE---KYREMMIVMRTT 1113
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
644-978 |
2.14e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 644 EPRETLEYKAALELEmwKEMQEDIFENQLKQKelahmqalAEEWKKRDRE--RESLVKKKVAEYTILEGKLQKTLIDLEK 721
Cdd:PTZ00121 1294 EAKKAEEKKKADEAK--KKAEEAKKADEAKKK--------AEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAE 1363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 722 REQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERL--------KIKQLEEDKHRLQQQLNDAENK 793
Cdd:PTZ00121 1364 EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAaaakkkadEAKKKAEEKKKADEAKKKAEEA 1443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 794 YKI--LEKEFQQFKDQQNNKPEIRLQSEINLLTlEKVELERKLESATKSKLHYKQQwGRALKELARLKQREQESQMARLK 871
Cdd:PTZ00121 1444 KKAdeAKKKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAKKK-ADEAKKAAEAKKKADEAKKAEEA 1521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 872 KQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRL 948
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeeKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601
|
330 340 350
....*....|....*....|....*....|
gi 96975038 949 IEERDTLMRTGVYNHEDRIISELDRQIREI 978
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
652-830 |
2.19e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 652 KAALELEMWKEMQE--DIFENQLKQKEL-AHMQALAEEWKKRDRERESLVKKKVAeytiLEGKLQKTLIDLEKRE-QQLA 727
Cdd:COG4913 266 AARERLAELEYLRAalRLWFAQRRLELLeAELEELRAELARLEAELERLEARLDA----LREELDELEAQIRGNGgDRLE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 728 SVESELQREKKELQsERQRNLQELQDSIR--------------RAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENK 793
Cdd:COG4913 342 QLEREIERLERELE-ERERRRARLEALLAalglplpasaeefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 96975038 794 YKILEKEFQQFKDQQNNKPE--IRLQSEIN-LLTLEKVEL 830
Cdd:COG4913 421 LRELEAEIASLERRKSNIPArlLALRDALAeALGLDEAEL 460
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
698-977 |
2.30e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.97 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 698 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRrakedcihQVELERLKIKQLE 777
Cdd:COG4372 8 VGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEE--------ELEQARSELEQLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 778 EDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELAR 857
Cdd:COG4372 80 EELEELNEQLQAAQAELAQAQEELESLQEEAE-----ELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 858 LkqreqESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVL 937
Cdd:COG4372 155 L-----EEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEA 229
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 96975038 938 EEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
Cdd:COG4372 230 KLGLALSALLDALELEEDKEELLEEVILKEIEELELAILV 269
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
639-926 |
2.39e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.52 E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKElahmqALAEEWKKRDRERE---SLVKKKVAEYTILEGKLQKT 715
Cdd:PRK03918 487 KVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKA-----EEYEKLKEKLIKLKgeiKSLKKELEKLEELKKKLAEL 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKE--DCIHQVELERLKIKQLEEDKHRLQQQLNDAENK 793
Cdd:PRK03918 562 EKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLElkDAEKELEREEKELKKLEEELDKAFEELAETEKR 641
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 794 YKILEKEFQQFKdQQNNKPEIRLQSEinlltlEKVELERKLEsatksklhykqqwgRALKELARLKQREQESqMARLKKQ 873
Cdd:PRK03918 642 LEELRKELEELE-KKYSEEEYEELRE------EYLELSRELA--------------GLRAELEELEKRREEI-KKTLEKL 699
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 96975038 874 QEELEQMRlryLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ-YQDSTEIAS 926
Cdd:PRK03918 700 KEELEERE---KAKKELEKLEKALERVEELREKVKKYKALLKERaLSKVGEIAS 750
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
639-916 |
2.51e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.97 E-value: 2.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALELEMWKEMQEDIfeNQLKQKELAHMQALaEEWKKRDRERESLVKKKVAEYTILEGKLQKTlid 718
Cdd:pfam07888 110 SEELSEEKDALLAQRAAHEARIRELEEDI--KTLTQRVLERETEL-ERMKERAKKAGAQRKEEEAERKQLQAKLQQT--- 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 719 lekrEQQLASVESELQrEKKELQSERQRNLQELQDSIRRA--KEDCIHQVELERlkiKQLEEDKHRLQQQLNDAENKYKI 796
Cdd:pfam07888 184 ----EEELRSLSKEFQ-ELRNSLAQRDTQVLQLQDTITTLtqKLTTAHRKEAEN---EALLEELRSLQERLNASERKVEG 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 797 LEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESATKSKLHYKQQWG---------------RALK---ELARL 858
Cdd:pfam07888 256 LGEELSSMAAQRD-----RTQAELHQARLQAAQLTLQLADASLALREGRARWAqeretlqqsaeadkdRIEKlsaELQRL 330
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 859 KQREQESQMARLKKQQE-----------------ELEQMR--LRyLAAEEKDTVKTERQELLDirnelnRLRQQEQK 916
Cdd:pfam07888 331 EERLQEERMEREKLEVElgrekdcnrvqlsesrrELQELKasLR-VAQKEKEQLQAEKQELLE------YIRQLEQR 400
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
743-913 |
2.93e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 2.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 743 ERQRNLQELQDSIRRAKEDC-IHQVELERLK---------IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkp 812
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIaELEKALAELRkeleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA--- 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 813 eiRLQSEINLLTLEKVELERKLESATKsklhykqqwgrALKELARLKQrEQESQMARLkkqQEELEQMRLRYLAAEEKdt 892
Cdd:TIGR02168 751 --QLSKELTELEAEIEELEERLEEAEE-----------ELAEAEAEIE-ELEAQIEQL---KEELKALREALDELRAE-- 811
|
170 180
....*....|....*....|.
gi 96975038 893 VKTERQELLDIRNELNRLRQQ 913
Cdd:TIGR02168 812 LTLLNEEAANLRERLESLERR 832
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
702-879 |
3.33e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.47 E-value: 3.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 702 VAEYTILEGKLQKTLIDLEKREQQLasveseLQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEdkh 781
Cdd:PRK12704 19 VIGYFVRKKIAEAKIKEAEEEAKRI------LEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK--- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 782 RLQQqlndaenKYKILEKefqqfKDQQNNKPEIRLQSEINLLTLEKVELERKLESAtkSKLHYKQQwgRALKELARLKQR 861
Cdd:PRK12704 90 RLLQ-------KEENLDR-----KLELLEKREEELEKKEKELEQKQQELEKKEEEL--EELIEEQL--QELERISGLTAE 153
|
170
....*....|....*...
gi 96975038 862 EQESQMarLKKQQEELEQ 879
Cdd:PRK12704 154 EAKEIL--LEKVEEEARH 169
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
642-923 |
3.47e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.21 E-value: 3.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQAlaEEWKKRDRERESL--VKKKVAEYTILEGKLQKTLIDL 719
Cdd:PTZ00121 1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA--EELKKAEEEKKKVeqLKKKEAEEKKKAEELKKAEEEN 1659
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 720 EKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEK 799
Cdd:PTZ00121 1660 KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE----AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 800 EFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQwgrALKELARLKQREQESQMARLKKQQEELEQ 879
Cdd:PTZ00121 1736 KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE---ELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 96975038 880 --MRLRYLAAEEKDTVKTERQELLDIRN-ELNRLRQQEQKQYQDSTE 923
Cdd:PTZ00121 1813 ggKEGNLVINDSKEMEDSAIKEVADSKNmQLEEADAFEKHKFNKNNE 1859
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
700-920 |
3.51e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.70 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 700 KKVAEYtilegKLQKTLIDLEKREQQLASVESELQREKKELQSERQRnLQELQDSIRRakedcihQVELERLKIKQLEED 779
Cdd:COG3206 196 AALEEF-----RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAE-AEARLAALRA-------QLGSGPDALPELLQS 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 780 KH--RLQQQLNDAENKYKILEKEFqqfkdqQNNKPEIR-LQSEINlltlekvELERKLESATksklhyKQQWGRALKELA 856
Cdd:COG3206 263 PViqQLRAQLAELEAELAELSARY------TPNHPDVIaLRAQIA-------ALRAQLQQEA------QRILASLEAELE 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 857 RLKQREQE--SQMARLKKQQEELEQMRLRYLAAEEKdtVKTERQELLDIRNELNRLRQQEQKQYQD 920
Cdd:COG3206 324 ALQAREASlqAQLAQLEARLAELPELEAELRRLERE--VEVARELYESLLQRLEEARLAEALTVGN 387
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
684-955 |
3.52e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.73 E-value: 3.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 684 AEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESEL------------QREK-----KELQSERQR 746
Cdd:PRK02224 344 AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIeelrerfgdapvDLGNaedflEELREERDE 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 747 ----------NLQELQDSIRRAK------------------------EDCIHQVELERLKIKQLEEDKHRLQQQLNDAEn 792
Cdd:PRK02224 424 lrereaeleaTLRTARERVEEAEalleagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAE- 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 793 KYKILEKEFQQFKDQQNNKPEIRLQSEINL---------LTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ 863
Cdd:PRK02224 503 DLVEAEDRIERLEERREDLEELIAERRETIeekreraeeLRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA 582
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 864 EsqmarLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELN------------RLRQQEQKQYQDSTEIASGKKDg 931
Cdd:PRK02224 583 E-----LKERIESLERIRTLLAAIADAEDEIERLREKREALAELNderrerlaekreRKRELEAEFDEARIEEAREDKE- 656
|
330 340
....*....|....*....|....
gi 96975038 932 pHGSVLEEGLDDYLTRLIEERDTL 955
Cdd:PRK02224 657 -RAEEYLEQVEEKLDELREERDDL 679
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
674-957 |
4.18e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.66 E-value: 4.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 674 QKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQktlidLEKREQQLASVESELQREKKELQSERQRNLQELQD 753
Cdd:TIGR00618 552 TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN-----ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 754 SIRRAKEDCIHQVELErlkikQLEEDKHRLQQQLNDAENKYKILE-KEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER 832
Cdd:TIGR00618 627 LQDVRLHLQQCSQELA-----LKLTALHALQLTLTQERVREHALSiRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQ 701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 833 K-------LESATKSKLHYKQQWGRALKELARLKQRE----------QESQMARLKKQQEELEQMRLRYLAAEEKDtvkT 895
Cdd:TIGR00618 702 CqtllrelETHIEEYDREFNEIENASSSLGSDLAAREdalnqslkelMHQARTVLKARTEAHFNNNEEVTAALQTG---A 778
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 96975038 896 ERQELldIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMR 957
Cdd:TIGR00618 779 ELSHL--AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLE 838
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
692-945 |
4.35e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 47.73 E-value: 4.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 692 RERESLVKKKVAEYTILEGK--LQKTLIDLEKRE-----QQLASVESELQREKKELqsERQRNLQELQDSIRRAKEDCIH 764
Cdd:TIGR00606 712 KSTESELKKKEKRRDEMLGLapGRQSIIDLKEKEipelrNKLQKVNRDIQRLKNDI--EEQETLLGTIMPEEESAKVCLT 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 765 QVELERLKIKQLEEDKHRLQQQLndAENKYKILEKEFQQFKDQQNNKpeirlQSEINLLTlEKVELERKLESATKSKLHY 844
Cdd:TIGR00606 790 DVTIMERFQMELKDVERKIAQQA--AKLQGSDLDRTVQQVNQEKQEK-----QHELDTVV-SKIELNRKLIQDQQEQIQH 861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 845 KQQWGRALK----ELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD 920
Cdd:TIGR00606 862 LKSKTNELKseklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941
|
250 260 270
....*....|....*....|....*....|.
gi 96975038 921 STEIASGKKDGPHG------SVLEEGLDDYL 945
Cdd:TIGR00606 942 KVNDIKEKVKNIHGymkdieNKIQDGKDDYL 972
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
654-913 |
4.89e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.42 E-value: 4.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 654 ALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKlQKTLIDL----EKREQQLASV 729
Cdd:pfam15921 437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESS-ERTVSDLtaslQEKERAIEAT 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 730 ESELQRekkeLQSERQRNLQELQ------DSIRRAKEDCihqvelERLKIKQLEEDK--HRLQQQLndaENKYKILEKEF 801
Cdd:pfam15921 516 NAEITK----LRSRVDLKLQELQhlknegDHLRNVQTEC------EALKLQMAEKDKviEILRQQI---ENMTQLVGQHG 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 802 QQFKDQQNNKPEirLQSEINLLTLEKVELerklesatksklhykqqwgRALKELARLKQREQESQMARLkkqqeELEQMR 881
Cdd:pfam15921 583 RTAGAMQVEKAQ--LEKEINDRRLELQEF-------------------KILKDKKDAKIRELEARVSDL-----ELEKVK 636
|
250 260 270
....*....|....*....|....*....|....*....
gi 96975038 882 LRYLAAEEKDTVKTERQELLDI-------RNELNRLRQQ 913
Cdd:pfam15921 637 LVNAGSERLRAVKDIKQERDQLlnevktsRNELNSLSED 675
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
643-917 |
5.65e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 5.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 643 TEPRETLEYKAALELEMWKEMQED---IFENQLKQKELAHMQA---LAEEWKKRDRERESLVKKKVAeytiLEGKLQKTL 716
Cdd:pfam01576 315 TAAQQELRSKREQEVTELKKALEEetrSHEAQLQEMRQKHTQAleeLTEQLEQAKRNKANLEKAKQA----LESENAELQ 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 717 IDLekREQQLASVESELQREKKELQ----------SERQRnlQELQDSIRRAkedcihQVELERLK--IKQLEEDKHRLQ 784
Cdd:pfam01576 391 AEL--RTLQQAKQDSEHKRKKLEGQlqelqarlseSERQR--AELAEKLSKL------QSELESVSslLNEAEGKNIKLS 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 785 QQLNDAENKYKILEKEFQQFKDQQNNkpeirLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQE 864
Cdd:pfam01576 461 KDVSSLESQLQDTQELLQEETRQKLN-----LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 96975038 865 SQMA------RLKKQQEELEQMRLRY----LAAEEKDTVKTE-RQELLDIRNELNRLRQ----QEQKQ 917
Cdd:pfam01576 536 DAGTlealeeGKKRLQRELEALTQQLeekaAAYDKLEKTKNRlQQELDDLLVDLDHQRQlvsnLEKKQ 603
|
|
| CEP63 |
pfam17045 |
Centrosomal protein of 63 kDa; CEP63 is a family of eukaryotic proteins involved in centriole ... |
662-917 |
5.96e-05 |
|
Centrosomal protein of 63 kDa; CEP63 is a family of eukaryotic proteins involved in centriole activity.
Pssm-ID: 465338 [Multi-domain] Cd Length: 264 Bit Score: 45.97 E-value: 5.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 662 EMQE-----DIFENQLKQKELAHMQALaeEWKKRDRERESLVKKKVAEYTILE-GKLQKTLIDLE--------KREQQLA 727
Cdd:pfam17045 7 ELQElmkqiDIMVAHKKSEWEGQTRAL--ETRLDIREEELLSARNTLERKHKEiGLLRQQLEELEkgkqelvaKYEQQLQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 728 SVESELQREKKELQSERQRNLQELQDSIRRAKEDcihQVELERLKIKQ-------LEEDKHRL--QQQLNDAENKYKILE 798
Cdd:pfam17045 85 KLQEELSKLKRSYEKLQRKQLKEAREEAKSREED---RSELSRLNGKLeefrqksLEWEQQRLqyQQQVASLEAQRKALA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 799 KEFQQFK-----DQQNNKPEI--RLQSEINLLTlekveleRKLESATKSkLHykqqwgralkelarlkqreqesqmarlk 871
Cdd:pfam17045 162 EQSSLIQsaayqVQLEGRKQCleASQSEIQRLR-------SKLERAQDS-LC---------------------------- 205
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 872 kqQEELEQMRLRYLAAEEKDTVKT---ERQELLD-----------IRNELNRLRQQEQKQ 917
Cdd:pfam17045 206 --AQELELERLRMRVSELGDSNRKlleEQQRLLEelrmsqrqlqvLQNELMELKATLQSQ 263
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
640-919 |
6.06e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.12 E-value: 6.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 640 EIQTEPRETLEYKAALELEMwKEMQE--DIFENQLKQKE------LAHMQALAEEWKKRDRERESL---VKKKVAEYTIL 708
Cdd:pfam10174 458 QREREDRERLEELESLKKEN-KDLKEkvSALQPELTEKEsslidlKEHASSLASSGLKKDSKLKSLeiaVEQKKEECSKL 536
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 709 EGKLQKTlidlekreQQLASVEselqREKKELqSERQRNLQelQDSIRRAKEDCIHQVELERL--KIKQLEEDKHrlqqq 786
Cdd:pfam10174 537 ENQLKKA--------HNAEEAV----RTNPEI-NDRIRLLE--QEVARYKEESGKAQAEVERLlgILREVENEKN----- 596
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 787 lnDAENKYKILEK-EFQQFKDQQNNKPEIR-LQSEINLLTLEKVELERKLESATKSKlHYKQQWGRALKELARLKQrEQE 864
Cdd:pfam10174 597 --DKDKKIAELESlTLRQMKEQNKKVANIKhGQQEMKKKGAQLLEEARRREDNLADN-SQQLQLEELMGALEKTRQ-ELD 672
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 865 SQMARL---------------------KKQQEELEQMRLRYL--AAEEKDT-----------VKTERQELLDIRNELNRL 910
Cdd:pfam10174 673 ATKARLsstqqslaekdghltnlraerRKQLEEILEMKQEALlaAISEKDAniallelssskKKKTQEEVMALKREKDRL 752
|
....*....
gi 96975038 911 RQQEQKQYQ 919
Cdd:pfam10174 753 VHQLKQQTQ 761
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
646-925 |
6.14e-05 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 46.45 E-value: 6.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 646 RETLEYKAALELEMWKEMQEDIF-----ENQLKQKELAHMQALAEEWKKRDRERESlvkkkvaeytilegKLQKTLIDLE 720
Cdd:pfam13868 36 AEEKEEERRLDEMMEEERERALEeeeekEEERKEERKRYRQELEEQIEEREQKRQE--------------EYEEKLQERE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 721 KREQQLASVESELQREKKELQSERQRNLQELQDSIR---RAKEDCIHQVELERLKIKQLEEDKHRLQQQLnDAENKYKIL 797
Cdd:pfam13868 102 QMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEeqaEWKELEKEEEREEDERILEYLKEKAEREEER-EAEREEIEE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 798 EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELErklesatksklhYKQQWGRALKELARLKQREQESQMARLKKQQEEL 877
Cdd:pfam13868 181 EKEREIARLRAQQEKAQDEKAERDELRAKLYQEE------------QERKERQKEREEAEKKARQRQELQQAREEQIELK 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 96975038 878 EQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIA 925
Cdd:pfam13868 249 ERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELE 296
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
722-889 |
6.21e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.26 E-value: 6.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 722 REQQLASVESELQrEKKELQSERQRNLQELQdsirRAKEDcihqveLERLKIKQL--------EEDKHRLQQQLNDAENK 793
Cdd:PRK04863 784 REKRIEQLRAERE-ELAERYATLSFDVQKLQ----RLHQA------FSRFIGSHLavafeadpEAELRQLNRRRVELERA 852
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 794 YKILEKEFQQFKDQ-QNNKPEI----RLQSEINLL---TLEK--VELERKLESATKSKLhYKQQWGRALKELarlkqreq 863
Cdd:PRK04863 853 LADHESQEQQQRSQlEQAKEGLsalnRLLPRLNLLadeTLADrvEEIREQLDEAEEAKR-FVQQHGNALAQL-------- 923
|
170 180
....*....|....*....|....*.
gi 96975038 864 ESQMARLKKQQEELEQMRLRYLAAEE 889
Cdd:PRK04863 924 EPIVSVLQSDPEQFEQLKQDYQQAQQ 949
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
783-915 |
7.63e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.55 E-value: 7.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 783 LQQQLNDAENKYKILEKEFQQFKdQQNNkpEIRLQSEINLLTLEKVELERKLESAT------KSKLHY-KQQWGRALKEL 855
Cdd:COG3206 180 LEEQLPELRKELEEAEAALEEFR-QKNG--LVDLSEEAKLLLQQLSELESQLAEARaelaeaEARLAAlRAQLGSGPDAL 256
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 96975038 856 ARLKQREQESQM-ARLKKQQEELEQMRLRYLAA--------EEKDTVKTERQE-----LLDIRNELNRLRQQEQ 915
Cdd:COG3206 257 PELLQSPVIQQLrAQLAELEAELAELSARYTPNhpdvialrAQIAALRAQLQQeaqriLASLEAELEALQAREA 330
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
639-986 |
7.86e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.65 E-value: 7.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEyKAALELEMWKEMQEDIFEN------QLKQKELAHMQALAEEWK----------KRDRERESLvkkKV 702
Cdd:pfam15921 137 SQSQEDLRNQLQ-NTVHELEAAKCLKEDMLEDsntqieQLRKMMLSHEGVLQEIRSilvdfeeasgKKIYEHDSM---ST 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 703 AEYTILEGKLQKTLIDLEKR----EQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDciHQVELERLKIK---- 774
Cdd:pfam15921 213 MHFRSLGSAISKILRELDTEisylKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISE--HEVEITGLTEKassa 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 775 ---------QLE--EDKHRLQ-----QQLNDAENKYKILEKEFQQFKDQQNNKPEiRLQSEINLLTLEKVE--LERKLES 836
Cdd:pfam15921 291 rsqansiqsQLEiiQEQARNQnsmymRQLSDLESTVSQLRSELREAKRMYEDKIE-ELEKQLVLANSELTEarTERDQFS 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 837 ATKSKLHYKQQwgralKELARLKQREQEsqmARLKKQQEEleqmRLRYLAAEEKDTVKTERQELLDIRNELNRL------ 910
Cdd:pfam15921 370 QESGNLDDQLQ-----KLLADLHKREKE---LSLEKEQNK----RLWDRDTGNSITIDHLRRELDDRNMEVQRLeallka 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 911 -RQQEQKQYQDSTEIASGKKDGPHG----SVLEEGLDDYLTRLIEERdTLMRTGVYNHEdRIISELDRQIREILAKSNAS 985
Cdd:pfam15921 438 mKSECQGQMERQMAAIQGKNESLEKvsslTAQLESTKEMLRKVVEEL-TAKKMTLESSE-RTVSDLTASLQEKERAIEAT 515
|
.
gi 96975038 986 N 986
Cdd:pfam15921 516 N 516
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
683-876 |
8.87e-05 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 46.10 E-value: 8.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 683 LAEEWKKRDRERESLVKKKVAEytiLEGKLQKtliDLEKREQQLASVESElQREKKELQSERQRNLQELQDSIRRAKEDC 762
Cdd:pfam15709 328 REQEKASRDRLRAERAEMRRLE---VERKRRE---QEEQRRLQQEQLERA-EKMREELELEQQRRFEEIRLRKQRLEEER 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 763 IHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQfKDQQNNKPEIRLQSEINLLTLEkvELERKLESATKSKL 842
Cdd:pfam15709 401 QRQEEEERKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQ-EEAERAEAEKQRQKELEMQLAE--EQKRLMEMAEEERL 477
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 96975038 843 HYKQQWGRAlKELARLK---QREQESQMARL-----KKQQEE 876
Cdd:pfam15709 478 EYQRQKQEA-EEKARLEaeeRRQKEEEAARLaleeaMKQAQE 518
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
638-951 |
1.10e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 46.28 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 638 PSEIqtePRETLEYKAALELEMWKEMQED-------IFENQLKQKELAHMQALAEEWKKR-----DRERESLVKKKVAEY 705
Cdd:pfam07111 232 PPEV---HSQTWELERQELLDTMQHLQEDradlqatVELLQVRVQSLTHMLALQEEELTRkiqpsDSLEPEFPKKCRSLL 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQElQDSIRRAKEDCIHQVELERLKIKQL-------EE 778
Cdd:pfam07111 309 NRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQE-QAILQRALQDKAAEVEVERMSAKGLqmelsraQE 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 779 DKHRLQQQLNDAENKYKI-----------LEKEFQQFKDQQNNKPE--------IRLQSEINLLTLEKVELER-KLESAT 838
Cdd:pfam07111 388 ARRRQQQQTASAEEQLKFvvnamsstqiwLETTMTRVEQAVARIPSlsnrlsyaVRKVHTIKGLMARKVALAQlRQESCP 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 839 KSKL-------------HYKQQWGRALKEL---ARLKQreQESQMARlkkQQEELEQMRLRYLAAEEKDTVKTERQELLD 902
Cdd:pfam07111 468 PPPPappvdadlsleleQLREERNRLDAELqlsAHLIQ--QEVGRAR---EQGEAERQQLSEVAQQLEQELQRAQESLAS 542
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 96975038 903 IRNELNRLRQQEQKQYQDSTEIAS--GKKDGPHGSVLEEGLDDYLTRLIEE 951
Cdd:pfam07111 543 VGQQLEVARQGQQESTEEAASLRQelTQQQEIYGQALQEKVAEVETRLREQ 593
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
652-834 |
1.19e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 45.44 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 652 KAALELEMwKEMQED-------IFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTI----LEGKLQKTLIDLE 720
Cdd:pfam15742 153 KKQLEERI-KEASENeaklkqqYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSQQQLriqqQEAQLKQLENEKR 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 721 KREQQLASVE------SELQREKKELQSERQRNLQELQDSIR--------------RAKEDCIHQVELERLKIKQLEEDK 780
Cdd:pfam15742 232 KSDEHLKSNQelseklSSLQQEKEALQEELQQVLKQLDVHVRkynekhhhhkaklrRAKDRLVHEVEQRDERIKQLENEI 311
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 96975038 781 HRLQQQLNdaenkykiLEKEFQQFKDQQNNKpeirlqseinlLTLEKVELERKL 834
Cdd:pfam15742 312 GILQQQSE--------KEKAFQKQVTAQNEI-----------LLLEKRKLLEQL 346
|
|
| Granin |
pfam01271 |
Granin (chromogranin or secretogranin); |
639-942 |
1.25e-04 |
|
Granin (chromogranin or secretogranin);
Pssm-ID: 279595 [Multi-domain] Cd Length: 584 Bit Score: 45.79 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQ-ALAEEWKKRDRERESLVKKKVAEYTilegklQKTLI 717
Cdd:pfam01271 98 NEPGGHSRENQPYALQVEKEFKTDHSDDYETQQWEEEKLKHMRfPLRYEENSEEKHSEREGELSEVFEN------PRSQA 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 718 DLEKREQQLASVESElQREKKELQSERQRNLQELQDSIRRAKEdciHQVELERLKIKQlEEDKHRLQQQLNDAENKYKIL 797
Cdd:pfam01271 172 TLKKVFEEVSRLDTP-SKQKREKSDEREKSSQESGEDTYRQEN---IPQEDQVGPEDQ-EPSEEGEEDATQEEVKRSRPR 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 798 EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQ--QE 875
Cdd:pfam01271 247 THHGRSLPDESSRGGQLGLEEEASEEEEEYGEESRGLSAVQTYLLRLVNARGRGRSEKRAERERSEESEEEELKRAspYE 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 876 ELEQMRLRYL--AAEEKDTVKTERQ-----------ELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLD 942
Cdd:pfam01271 327 ELEITANLQIppSEEERMLKKAGRSprgrvdeagalEALEALEEKRKLDLDHSRVFESSEDGAPRAPQGAWVEALRNYLS 406
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
719-916 |
1.28e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 45.62 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 719 LEKREQQLASVESELQREK---KELQSERQRNLQELQDSIRRAKEDCIH------QVELERLKiKQLEEDKHRLQQ-QLN 788
Cdd:pfam06160 181 LEKLEEETDALEELMEDIPplyEELKTELPDQLEELKEGYREMEEEGYAlehlnvDKEIQQLE-EQLEENLALLENlELD 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 789 DAENK-----------YKILEKEFQQFKDQQNNKPEIRlqSEINLLTLEKVELERKLEsatksklHYKQQWGRALKELAR 857
Cdd:pfam06160 260 EAEEAleeieeridqlYDLLEKEVDAKKYVEKNLPEIE--DYLEHAEEQNKELKEELE-------RVQQSYTLNENELER 330
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 858 lkQREQESQMARLKKQQEELEQ-----------MRLRYLAAEEKDTVKTERQEllDIRNELNRLRQQEQK 916
Cdd:pfam06160 331 --VRGLEKQLEELEKRYDEIVErleekevayseLQEELEEILEQLEEIEEEQE--EFKESLQSLRKDELE 396
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
708-890 |
1.42e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 708 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRnLQELQDSIRRAKEdcihqvELERLKiKQLEEDKHRLQQQL 787
Cdd:COG3883 21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-LEALQAEIDKLQA------EIAEAE-AEIEERREELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 788 NDAenkYK----------ILE-KEFQQFKDQ---------QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQ 847
Cdd:COG3883 93 RAL---YRsggsvsyldvLLGsESFSDFLDRlsalskiadADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 96975038 848 wgraLKELARlKQREQESQMARLKKQQEELEQMRLRYLAAEEK 890
Cdd:COG3883 170 ----KAELEA-QQAEQEALLAQLSAEEAAAEAQLAELEAELAA 207
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
698-870 |
1.76e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 698 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQS-ERQRNLQELQDSIRRAKE------DCIHQVELER 770
Cdd:COG4717 76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAelaelpERLEELEERL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 771 LKIKQLEEDKHRLQQQLNDAENKykiLEKEFQQFkDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGR 850
Cdd:COG4717 156 EELRELEEELEELEAELAELQEE---LEELLEQL-SLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
|
170 180
....*....|....*....|
gi 96975038 851 ALKELARLKQREQESQMARL 870
Cdd:COG4717 232 LENELEAAALEERLKEARLL 251
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
706-979 |
1.84e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.70 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDkhrlqq 785
Cdd:COG1196 581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE------ 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 786 QLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQES 865
Cdd:COG1196 655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 866 QMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRL------------RQQEQKQYqdsteiasgkkdgph 933
Cdd:COG1196 735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaieeyeELEERYDF--------------- 799
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 96975038 934 gsvLEEGLDDyltrLIEERDTLMrtgvynhedRIISELDRQIREIL 979
Cdd:COG1196 800 ---LSEQRED----LEEARETLE---------EAIEEIDRETRERF 829
|
|
| C2 |
pfam00168 |
C2 domain; |
9-114 |
1.98e-04 |
|
C2 domain;
Pssm-ID: 425499 [Multi-domain] Cd Length: 104 Bit Score: 41.54 E-value: 1.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 9 LIVVSILEGRHFPKRPKHMLV---VEAKFDGEQ--LATDPVDHTDQPEFATELAWEIdrkalhqHRLQRTPIKLQCFALD 83
Cdd:pfam00168 2 RLTVTVIEAKNLPPKDGNGTSdpyVKVYLLDGKqkKKTKVVKNTLNPVWNETFTFSV-------PDPENAVLEIEVYDYD 74
|
90 100 110
....*....|....*....|....*....|.
gi 96975038 84 pVTSAKETIGYIVLDLRTAQETKQAPKWYQL 114
Cdd:pfam00168 75 -RFGRDDFIGEVRIPLSELDSGEGLDGWYPL 104
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
602-955 |
2.04e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 602 LEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPretlEYKAALELEMwKEMQEDIFENQLKQKELAHMQ 681
Cdd:TIGR00618 175 LDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYH----ERKQVLEKEL-KHLREALQQTQQSHAYLTQKR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 682 ALAEEWKKRDRERESLVKKkVAEYTILEGKLQKTLIDLEKR----------------EQQLASVESELQREKKELQSERQ 745
Cdd:TIGR00618 250 EAQEEQLKKQQLLKQLRAR-IEELRAQEAVLEETQERINRArkaaplaahikavtqiEQQAQRIHTELQSKMRSRAKLLM 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 746 R---------NLQELQDSIRRAKEDCIH----------------QVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKE 800
Cdd:TIGR00618 329 KraahvkqqsSIEEQRRLLQTLHSQEIHirdahevatsireiscQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 801 F--QQFKDQQNNKPEIRL---------------------QSEINLLTLEKVELE------RKLESATKSKLHYKQQWGRA 851
Cdd:TIGR00618 409 QatIDTRTSAFRDLQGQLahakkqqelqqryaelcaaaiTCTAQCEKLEKIHLQesaqslKEREQQLQTKEQIHLQETRK 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 852 LKELARLKQREQESQmARLKKQQEELEQ---------------MRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK 916
Cdd:TIGR00618 489 KAVVLARLLELQEEP-CPLCGSCIHPNParqdidnpgpltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQE 567
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 96975038 917 QYQDSTEIA----SGKKDGPHGSVLEEGLDDYLTRLIEERDTL 955
Cdd:TIGR00618 568 IQQSFSILTqcdnRSKEDIPNLQNITVRLQDLTEKLSEAEDML 610
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
732-930 |
2.14e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.89 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 732 ELQREKKELQSER---QRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILE-------KEF 801
Cdd:pfam07888 38 ECLQERAELLQAQeaaNRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSasseelsEEK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 802 QQFKDQQ-NNKPEIR-LQSEINLLTLEKVELERKLESATKsklhykqqwgRALKELARLKQREQESQMARLKKQQEELEQ 879
Cdd:pfam07888 118 DALLAQRaAHEARIReLEEDIKTLTQRVLERETELERMKE----------RAKKAGAQRKEEEAERKQLQAKLQQTEEEL 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 96975038 880 MRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
Cdd:pfam07888 188 RSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEE 238
|
|
| CCDC34 |
pfam13904 |
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ... |
668-812 |
2.27e-04 |
|
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.
Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 43.54 E-value: 2.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 668 FENQLKQKELAHMQ-ALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESElQREKKELQSERQR 746
Cdd:pfam13904 57 YENWLAAKQRQRQKeLQAQKEEREKEEQEAELRKRLAKEKYQEWLQRKARQQTKKREESHKQKAAE-SASKSLAKPERKV 135
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 747 nlqeLQDSIRRAKEDCIhQVELERLKIKQLEEDKHRLQQQLNDAENKyKILEKEFQQFKDQQNNKP 812
Cdd:pfam13904 136 ----SQEEAKEVLQEWE-RKKLEQQQRKREEEQREQLKKEEEEQERK-QLAEKAWQKWMKNVKNKP 195
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
723-923 |
2.36e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 45.04 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 723 EQQLASVESELQREKKELQSERQRnLQELQDSIrrakedcihqvelerLKIKQLEEDKHRlqqQLNDAENKYKILEKEFQ 802
Cdd:PRK10929 108 EQEILQVSSQLLEKSRQAQQEQDR-AREISDSL---------------SQLPQQQTEARR---QLNEIERRLQTLGTPNT 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 803 QFKDQQNnkpeIRLQSEINLLTLEKVELERKLESAtksklHYKQqwgralkELARLkqreqesQMARLKKQQEELEQmrl 882
Cdd:PRK10929 169 PLAQAQL----TALQAESAALKALVDELELAQLSA-----NNRQ-------ELARL-------RSELAKKRSQQLDA--- 222
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 96975038 883 rylaaeekdtvkterqELLDIRNELNRLRQQEQKQYQDSTE 923
Cdd:PRK10929 223 ----------------YLQALRNQLNSQRQREAERALESTE 247
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
719-909 |
2.59e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 44.70 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 719 LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEdkhRLQQQLNDAENKYKile 798
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEE---RLVQKEEQLDARAE--- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 799 kefqqfkdqqnnkpeirlqsEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEElE 878
Cdd:PRK12705 99 --------------------KLDNLENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELE-E 157
|
170 180 190
....*....|....*....|....*....|.
gi 96975038 879 QMRLRYLAAEEKDTVKTERQELLDIRNELNR 909
Cdd:PRK12705 158 EKAQRVKKIEEEADLEAERKAQNILAQAMQR 188
|
|
| MscS_porin |
pfam12795 |
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part ... |
691-923 |
2.69e-04 |
|
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this MscS_porin is towards the N-terminal of the molecules. The high concentration of negative charges at the extracellular entrance of the pore helps select the cations for efflux.
Pssm-ID: 432790 [Multi-domain] Cd Length: 238 Bit Score: 43.44 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 691 DRERESLVKKKVAEYtilegkLQKTLIDLEKRE---QQLASVESELQREKKELQsERQRNLQELQDSIRRAKedcihQVE 767
Cdd:pfam12795 7 KAKLDEAAKKKLLQD------LQQALSLLDKIDaskQRAAAYQKALDDAPAELR-ELRQELAALQAKAEAAP-----KEI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 768 LERLKIKQLEedkhrlqQQLNDAENKYKILEKEFQQFKDQ---QNNKPEiRLQSEINLLTLEKVELERKLESATKSKlhy 844
Cdd:pfam12795 75 LASLSLEELE-------QRLLQTSAQLQELQNQLAQLNSQlieLQTRPE-RAQQQLSEARQRLQQIRNRLNGPAPPG--- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 845 kQQWGRALKELARLKQREQESQMARLKKQQE------ELEQMRLRYLAAEekdtVKTERQELLDIRNELNRLRQQEQKQY 918
Cdd:pfam12795 144 -EPLSEAQRWALQAELAALKAQIDMLEQELLsnnnrqDLLKARRDLLTLR----IQRLEQQLQALQELLNEKRLQEAEQA 218
|
....*
gi 96975038 919 QDSTE 923
Cdd:pfam12795 219 VAQTE 223
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
711-930 |
2.79e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 711 KLQKTLIDLEKREQQLASVES---ELQREKKELQSERQRNLQELQDsirraKEDCIHQVELERLK-------IKQLEEDK 780
Cdd:TIGR04523 139 NIDKFLTEIKKKEKELEKLNNkynDLKKQKEELENELNLLEKEKLN-----IQKNIDKIKNKLLKlelllsnLKKKIQKN 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 781 HRLQQQLNDAENKYKILEKEFQQfkdqqnnkpeirLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQ 860
Cdd:TIGR04523 214 KSLESQISELKKQNNQLKDNIEK------------KQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNK 281
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 96975038 861 R--EQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNrlrQQEQKQYQDSTEIASGKKD 930
Cdd:TIGR04523 282 KikELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS---QNNKIISQLNEQISQLKKE 350
|
|
| CCDC34 |
pfam13904 |
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ... |
713-889 |
2.91e-04 |
|
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.
Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 43.54 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 713 QKTLIDLEKREQQLASVESELQREKKELQSERQRNLQElqdsirRAKEDcihqvelerlkikQLEEDKHRLqqqlndAEN 792
Cdd:pfam13904 41 ARKLEGLKLERQPLEAYENWLAAKQRQRQKELQAQKEE------REKEE-------------QEAELRKRL------AKE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 793 KYK--ILEKEFQQFKDQQNNKPeirlQSEINLLTLEKVELERKlESATKSKLHYKQQWgraLKELARLKQREQESQMARL 870
Cdd:pfam13904 96 KYQewLQRKARQQTKKREESHK----QKAAESASKSLAKPERK-VSQEEAKEVLQEWE---RKKLEQQQRKREEEQREQL 167
|
170
....*....|....*....
gi 96975038 871 KKQQEELEQMRLRYLAAEE 889
Cdd:pfam13904 168 KKEEEEQERKQLAEKAWQK 186
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
639-800 |
3.57e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 3.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALElEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQktliD 718
Cdd:TIGR02169 301 AEIASLERSIAEKERELE-DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE----E 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 719 LEKREQQLASVESELQREKKELQSER---QRNLQELQDSIRRA------------------------KEDCIHQVELERL 771
Cdd:TIGR02169 376 VDKEFAETRDELKDYREKLEKLKREInelKRELDRLQEELQRLseeladlnaaiagieakineleeeKEDKALEIKKQEW 455
|
170 180
....*....|....*....|....*....
gi 96975038 772 KIKQLEEDKHRLQQQLNDAENKYKILEKE 800
Cdd:TIGR02169 456 KLEQLAADLSKYEQELYDLKEEYDRVEKE 484
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
643-916 |
4.01e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 643 TEPRETLEYKAAlELEMWKEMQEDiFENQLKQKELAH-------------MQALAEEWKKRDRERESLVKKKvaeytile 709
Cdd:pfam01576 1 TRQEEEMQAKEE-ELQKVKERQQK-AESELKELEKKHqqlceeknalqeqLQAETELCAEAEEMRARLAARK-------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 710 GKLQKTLIDLEKREQQLASVESELQREKKELQSerqrNLQELQDSIRrAKEDCIHQVELERL----KIKQLEEDKHRLQQ 785
Cdd:pfam01576 71 QELEEILHELESRLEEEEERSQQLQNEKKKMQQ----HIQDLEEQLD-EEEAARQKLQLEKVtteaKIKKLEEDILLLED 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 786 QLNDAENKYKILEKEFQQFKDQQNNKPE--IRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQR-- 861
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEkaKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQia 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 96975038 862 EQESQMARLK----KQQEELE--QMRLRYLAAEEKDTVKTERQ---ELLDIRNELNRLRQQEQK 916
Cdd:pfam01576 226 ELQAQIAELRaqlaKKEEELQaaLARLEEETAQKNNALKKIREleaQISELQEDLESERAARNK 289
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
770-923 |
5.22e-04 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 42.20 E-value: 5.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 770 RLKIKQLEEDKHRLQQQLNDAENKYKIL-------EKEFQQFKDQQNNKPEI--RLQSEINLLTLEKVELERKLESATKS 840
Cdd:pfam15619 10 LHKIKELQNELAELQSKLEELRKENRLLkrlqkrqEKALGKYEGTESELPQLiaRHNEEVRVLRERLRRLQEKERDLERK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 841 KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKdTVKTERQ-ELLDirNELNRLRQQEQKQYQ 919
Cdd:pfam15619 90 LKEKEAELLRLRDQLKRLEKLSEDKNLAEREELQKKLEQLEAKLEDKDEK-IQDLERKlELEN--KSFRRQLAAEKKKHK 166
|
....
gi 96975038 920 DSTE 923
Cdd:pfam15619 167 EAQE 170
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
661-876 |
5.40e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 5.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 661 KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLasvESELQREKKEL 740
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL---RAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 741 --------QSERQRNLQEL------QDSIRRAKEdcIHQVELERLK-IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFK 805
Cdd:COG4942 107 aellralyRLGRQPPLALLlspedfLDAVRRLQY--LKYLAPARREqAEELRADLAELAALRAELEAERAELEALLAELE 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 96975038 806 DQQNnkpeiRLQSEINlltlEKVELERKLESATKSKlhykqqwgraLKELARLKQREQ--ESQMARLKKQQEE 876
Cdd:COG4942 185 EERA-----ALEALKA----ERQKLLARLEKELAEL----------AAELAELQQEAEelEALIARLEAEAAA 238
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
674-930 |
5.46e-04 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 43.49 E-value: 5.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 674 QKELAHMQALAEEWKKRDRERESLvkkkvaEYTILEGKLQKTLIDLEKRE---QQLASVESELQREKKELQSERQRNLQE 750
Cdd:pfam15558 37 LRRRDQKRQETLERERRLLLQQSQ------EQWQAEKEQRKARLGREERRradRREKQVIEKESRWREQAEDQENQRQEK 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 751 LQDSIRRAKEDCIHQVelERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLeKVEL 830
Cdd:pfam15558 111 LERARQEAEQRKQCQE--QRLKEKEEELQALREQNSLQLQERLEEACHKRQLKEREEQKKVQENNLSELLNHQAR-KVLV 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 831 ERK-----------LE-SATKSKLHYKQQWGRALKEL-ARLKQREQESQMARLK-KQQEELEQMRLRYLAAEEK------ 890
Cdd:pfam15558 188 DCQakaeellrrlsLEqSLQRSQENYEQLVEERHRELrEKAQKEEEQFQRAKWRaEEKEEERQEHKEALAELADrkiqqa 267
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 96975038 891 -----DTVKTERQELLDIRNE------LNRLR-QQEQKQYQDSTEIASGKKD 930
Cdd:pfam15558 268 rqvahKTVQDKAQRARELNLEreknhhILKLKvEKEEKCHREGIKEAIKKKE 319
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
643-975 |
6.56e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.67 E-value: 6.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 643 TEPRETLEYKAALE----LEMWKEMQEDIFENQLKQKELA--HMQALAEEW-------KKRDRERESLVKKKVAEYTIL- 708
Cdd:pfam12128 374 TAKYNRRRSKIKEQnnrdIAGIKDKLAKIREARDRQLAVAedDLQALESELreqleagKLEFNEEEYRLKSRLGELKLRl 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 709 -------EGKLQKTLIDL------EKREQQLASVESeLQREKKELQSERQRNLQELQDSIRRAKEdciHQVELERLKiKQ 775
Cdd:pfam12128 454 nqatatpELLLQLENFDErierarEEQEAANAEVER-LQSELRQARKRRDQASEALRQASRRLEE---RQSALDELE-LQ 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 776 LEEDKHRLQQQLND-----AENKYKILEKEFQQFKDQQnnkPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGR 850
Cdd:pfam12128 529 LFPQAGTLLHFLRKeapdwEQSIGKVISPELLHRTDLD---PEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRER 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 851 ALK-----ELARLKQREQESQMARLKKQQEEL---------------------------EQMRLRYLAAEEKDTVKTERQ 898
Cdd:pfam12128 606 LDKaeealQSAREKQAAAEEQLVQANGELEKAsreetfartalknarldlrrlfdekqsEKDKKNKALAERKDSANERLN 685
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 899 ElLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLmRTGVYNHEDRIISELDRQI 975
Cdd:pfam12128 686 S-LEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAAR-RSGAKAELKALETWYKRDL 760
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
655-879 |
6.95e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 42.70 E-value: 6.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 655 LELEMW--KEMQEDI-----FENQLKQKELAHMQALAEEWKKRDRERESLVKKK---VAEYTILEGK---------LQKT 715
Cdd:smart00787 65 LELYQFscKELKKYIsegrdLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQfqlVKTFARLEAKkmwyewrmkLLEG 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 716 LIDlekreqQLASVESELQREKKELQSERQRnLQELQDSIRRAKEDCIHQVELERlkikQLEEDKHRLQQ-QLNDAENKY 794
Cdd:smart00787 145 LKE------GLDENLEGLKEDYKLLMKELEL-LNSIKPKLRDRKDALEEELRQLK----QLEDELEDCDPtELDRAKEKL 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 795 KILEKEFQQFKDQQNNkpeirlqseinlLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREqESQMARLKKQQ 874
Cdd:smart00787 214 KKLLQEIMIKVKKLEE------------LEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFT-FKEIEKLKEQL 280
|
....*
gi 96975038 875 EELEQ 879
Cdd:smart00787 281 KLLQS 285
|
|
| BRE1 |
pfam08647 |
BRE1 E3 ubiquitin ligase; BRE1 is an E3 ubiquitin ligase that has been shown to act as a ... |
674-791 |
1.43e-03 |
|
BRE1 E3 ubiquitin ligase; BRE1 is an E3 ubiquitin ligase that has been shown to act as a transcriptional activator through direct activator interactions.
Pssm-ID: 462547 [Multi-domain] Cd Length: 95 Bit Score: 38.72 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 674 QKELAHMQAlaeEWKKRDrereSLVKKKVAEYTILEGKLQKTLIDLEKREQQLAsvesELQREKKELQSERqRNLQelqd 753
Cdd:pfam08647 2 QTELVKLEQ---AFEELS----EQLDKKVKDLTILEEKKLRLEAEKAKADQKYF----AAMRSKDALENEN-KKLN---- 65
|
90 100 110
....*....|....*....|....*....|....*...
gi 96975038 754 sirrakedciHQVELERLKIKQLEEDKHRLQQQLNDAE 791
Cdd:pfam08647 66 ----------TLLSKSSELIEQLKETEKEFVRKLKNLE 93
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
771-927 |
1.83e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 771 LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDqqnnkpeirlqsEINLLTLEKVELERKLESATKSKLHYKQQWG- 849
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKT------------ELEDLEKEIKRLELEIEEVEARIKKYEEQLGn 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 850 -RALKELARLkQREQESQMARLKK-QQEELEQM----RLRYLAAEEKDTVKTERQELLDIRNELN----RLRQQEQKQYQ 919
Cdd:COG1579 85 vRNNKEYEAL-QKEIESLKRRISDlEDEILELMerieELEEELAELEAELAELEAELEEKKAELDeelaELEAELEELEA 163
|
....*...
gi 96975038 920 DSTEIASG 927
Cdd:COG1579 164 EREELAAK 171
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
727-858 |
2.01e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.15 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 727 ASVESELQREKKELQSERQRNLQELQDSIRRAKEDciHQVELERL--KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQF 804
Cdd:COG2433 376 LSIEEALEELIEKELPEEEPEAEREKEHEERELTE--EEEEIRRLeeQVERLEAEVEELEAELEEKDERIERLERELSEA 453
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 805 KDQQNNkpEIRLQSEINLLTLEKVELERKLESA--TKSKLHYKQQwgrALKELARL 858
Cdd:COG2433 454 RSEERR--EIRKDREISRLDREIERLERELEEEreRIEELKRKLE---RLKELWKL 504
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
641-912 |
2.07e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.34 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 641 IQTEPRETLEYKAALE-LEMWKEMQEDIfENQLKQKElAHMQALAEEWKKRDRERESLVK--KKVAEYTILEGKLQKTLI 717
Cdd:TIGR00606 195 RQTQGQKVQEHQMELKyLKQYKEKACEI-RDQITSKE-AQLESSREIVKSYENELDPLKNrlKEIEHNLSKIMKLDNEIK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 718 DLEKREQQLASVESEL----------------------QREKKELQSERQRNLQELQDSIRRAKEDCIHQVELE-RLKIK 774
Cdd:TIGR00606 273 ALKSRKKQMEKDNSELelkmekvfqgtdeqlndlyhnhQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLvEQGRL 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 775 QLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRlqseiNLLTLEKVELERKLESATK------SKLHYKQQW 848
Cdd:TIGR00606 353 QLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIK-----NFHTLVIERQEDEAKTAAQlcadlqSKERLKQEQ 427
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 849 GRALKELARLKQREQESQMARLKKQQEELEQMR--LRYLAAEEKDTVKTErQELLDIRNELNRLRQ 912
Cdd:TIGR00606 428 ADEIRDEKKGLGRTIELKKEILEKKQEELKFVIkeLQQLEGSSDRILELD-QELRKAERELSKAEK 492
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
644-917 |
2.09e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.13 E-value: 2.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 644 EPRETLEYKAAL------ELEMWKEMQEDIFENQLKQKELaHMQALAEEWK-KRDRERESL------VKKKVAEYTILEG 710
Cdd:pfam12128 251 NTLESAELRLSHlhfgykSDETLIASRQEERQETSAELNQ-LLRTLDDQWKeKRDELNGELsaadaaVAKDRSELEALED 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 711 KLQKTL-IDLEKREQ---QLASVESEL--QREKKELQSERQRNLQELQDSiRRAKEDCIHQVELERLKiKQLEEDKHRLQ 784
Cdd:pfam12128 330 QHGAFLdADIETAAAdqeQLPSWQSELenLEERLKALTGKHQDVTAKYNR-RRSKIKEQNNRDIAGIK-DKLAKIREARD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 785 QQLNDAENKYKILEKEFQQFKDQQNNkpEIRLQSEINLLTLEkvELERKLESATKSKlhykqqwgrALKElarlkqrEQE 864
Cdd:pfam12128 408 RQLAVAEDDLQALESELREQLEAGKL--EFNEEEYRLKSRLG--ELKLRLNQATATP---------ELLL-------QLE 467
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 96975038 865 SQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ 917
Cdd:pfam12128 468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQS 520
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
623-921 |
2.13e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.21 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 623 SAVQQKPSSLPPAPCPSEIQTEPRETLEykAALE-LEMWKEMQEDIfeNQLKQK------ELAHMQALAEEWKKRDRE-- 693
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQDLE--QTLAlLDKIDRQKEET--EQLKQQlaqapaKLRQAQAELEALKDDNDEet 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 694 RESLVKKKVAEytiLEGKLQKTLIDLEKREQQLASVESEL--QREKKE-LQSERQRNLQELQdsirrakedcihqvELER 770
Cdd:PRK11281 115 RETLSTLSLRQ---LESRLAQTLDQLQNAQNDLAEYNSQLvsLQTQPErAQAALYANSQRLQ--------------QIRN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 771 LKIKQLEEDK---HRLQQQLNdAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLEsatksklhykqq 847
Cdd:PRK11281 178 LLKGGKVGGKalrPSQRVLLQ-AEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQ------------ 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 96975038 848 wgrALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQ--KQYQDS 921
Cdd:PRK11281 245 ---LLQEAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNLrvKNWLDR 317
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
708-810 |
2.19e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.12 E-value: 2.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 708 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQEL----QDSIRRAKE--DCIHQVELERLKIKQLEEDKH 781
Cdd:PRK00409 528 LERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAekeaQQAIKEAKKeaDEIIKELRQLQKGGYASVKAH 607
|
90 100
....*....|....*....|....*....
gi 96975038 782 RLQQQLNDAENKYKILEKEFQQFKDQQNN 810
Cdd:PRK00409 608 ELIEARKRLNKANEKKEKKKKKQKEKQEE 636
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
684-925 |
2.19e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.05 E-value: 2.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 684 AEEWKKRDRERESLVKKKVAEYTILEGklqktlidlEKREQQLASVESELQREKKELQSERQRNLQElqdsIRRAKEDCI 763
Cdd:PTZ00121 1196 AEDARKAEAARKAEEERKAEEARKAED---------AKKAEAVKKAEEAKKDAEEAKKAEEERNNEE----IRKFEEARM 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 764 HQVELERLKIKQLEEDKhrlQQQLNDAENKYKilekefqqfKDQQNNKPEIRLQSEINlltlEKVELERKLESATKSKLH 843
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARK---ADELKKAEEKKK---------ADEAKKAEEKKKADEAK----KKAEEAKKADEAKKKAEE 1326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 844 YKQQwGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 923
Cdd:PTZ00121 1327 AKKK-ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405
|
..
gi 96975038 924 IA 925
Cdd:PTZ00121 1406 KA 1407
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
660-823 |
2.30e-03 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 41.02 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 660 WKEMQEDIFE--NQLKQKELAHMQALAEEWKKrdrereslvKKKVAEyTILEGKLQKTLIDLEKREQQLASVESELQREK 737
Cdd:cd16269 147 YLEDREKLVEkyRQVPRKGVKAEEVLQEFLQS---------KEAEAE-AILQADQALTEKEKEIEAERAKAEAAEQERKL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 738 KElqsERQRNL-QELQDSIRRakedciHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNkpeiRL 816
Cdd:cd16269 217 LE---EQQRELeQKLEDQERS------YEEHLRQLKEKMEEERENLLKEQERALESKLKEQEALLEEGFKEQAE----LL 283
|
....*..
gi 96975038 817 QSEINLL 823
Cdd:cd16269 284 QEEIRSL 290
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
673-898 |
2.34e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 2.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 673 KQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQseRQRNLQELQ 752
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIA 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 753 DSIRRAKEDCIHQVeleRLKIKQLEEdKHRLQQQLNDAENKykiLEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER 832
Cdd:COG4717 374 ALLAEAGVEDEEEL---RAALEQAEE-YQELKEELEELEEQ---LEELLGELEELLEALDEEELEEELEELEEELEELEE 446
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 96975038 833 KLESATKSKLHYKQQWgRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAA---EEKDTVKTERQ 898
Cdd:COG4717 447 ELEELREELAELEAEL-EQLEEDGELAELLQELEELKAELRELAEEWAALKLALElleEAREEYREERL 514
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
646-842 |
3.01e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 646 RETLEYKAALELEMWKEMQEDIFENQLKQKELAhmQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLI------DL 719
Cdd:COG4942 57 LAALERRIAALARRIRALEQELAALEAELAELE--KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLspedflDA 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 720 EKREQQLASVESELQREKKELQSERQRnLQELQDSIRRAKEdcihqvELERLKiKQLEEDKHRLQQQLNDAENKYKILEK 799
Cdd:COG4942 135 VRRLQYLKYLAPARREQAEELRADLAE-LAALRAELEAERA------ELEALL-AELEEERAALEALKAERQKLLARLEK 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 96975038 800 EFQQFKDQ--QNNKPEIRLQSEINLLTLEKVELERKLESATKSKL 842
Cdd:COG4942 207 ELAELAAElaELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
652-941 |
3.71e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 3.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 652 KAALELEMWK------EMQEDIFEN-----QLKQKELAHMQalaEEWKKRDRERESLVKKKvAEYTILEGKLQ------- 713
Cdd:TIGR00606 285 NSELELKMEKvfqgtdEQLNDLYHNhqrtvREKERELVDCQ---RELEKLNKERRLLNQEK-TELLVEQGRLQlqadrhq 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 714 --KTLIDLEKREQQLasvESELQREKKELQSERQ-RNLQEL-----QDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
Cdd:TIGR00606 361 ehIRARDSLIQSLAT---RLELDGFERGPFSERQiKNFHTLvierqEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKG 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 786 QLNDAENKYKILEKEFQQFKDqqnnkpeirlqseinlltleKVELERKLESATKSKLHYKQQWGRALKELARL-KQREQE 864
Cdd:TIGR00606 438 LGRTIELKKEILEKKQEELKF--------------------VIKELQQLEGSSDRILELDQELRKAERELSKAeKNSLTE 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 865 SQMARLKK-QQEELEQMR-LRYLAAE--EKDTVKTERQELLDI-RNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE 939
Cdd:TIGR00606 498 TLKKEVKSlQNEKADLDRkLRKLDQEmeQLNHHTTTRTQMEMLtKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 577
|
..
gi 96975038 940 GL 941
Cdd:TIGR00606 578 WL 579
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
711-906 |
3.81e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 41.04 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 711 KLQKTL-IDLEKREQQLASVESELQREKKELQ------SERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHR- 782
Cdd:pfam15964 371 RLEKELaSQQEKRAQEKEALRKEMKKEREELGatmlalSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKv 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 783 ---LQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQsEINLLTLEKVELERKLESAtksklhyKQQWGRALKELAR-- 857
Cdd:pfam15964 451 cgeMRYQLNQTKMKKDEAEKEHREYRTKTGRQLEIKDQ-EIEKLGLELSESKQRLEQA-------QQDAARAREECLKlt 522
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 96975038 858 --LKQREQESQMARLKK---QQEELEQMRLRYLAAEEKDTVKTERQELLDIRNE 906
Cdd:pfam15964 523 elLGESEHQLHLTRLEKesiQQSFSNEAKAQALQAQQREQELTQKMQQMEAQHD 576
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
701-985 |
3.83e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 3.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 701 KVAEYTILEGKLQKTLIDLEKREQQLASVE--SELQREKKELQSERQRNLQELQDSIR---------------------- 756
Cdd:PRK04863 339 LVQTALRQQEKIERYQADLEELEERLEEQNevVEEADEQQEENEARAEAAEEEVDELKsqladyqqaldvqqtraiqyqq 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 757 ------RAKEDC------IHQVE--LERLKIKQLEEDKHRLQ--QQLNDAENKYKILEKEFQQFKdqqnnkpeiRLQSEI 820
Cdd:PRK04863 419 avqaleRAKQLCglpdltADNAEdwLEEFQAKEQEATEELLSleQKLSVAQAAHSQFEQAYQLVR---------KIAGEV 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 821 NLLTLEKV--ELERKLESAtKSKLHYKQQWGRALKELAR--LKQREQESQMARLKKQ--------------QEELEQMR- 881
Cdd:PRK04863 490 SRSEAWDVarELLRRLREQ-RHLAEQLQQLRMRLSELEQrlRQQQRAERLLAEFCKRlgknlddedeleqlQEELEARLe 568
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 882 -LRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK--QYQDSTEiasgkKDGPH-GSVLE--EGLDDYLTRLIE-ERDT 954
Cdd:PRK04863 569 sLSESVSEARERRMALRQQLEQLQARIQRLAARAPAwlAAQDALA-----RLREQsGEEFEdsQDVTEYMQQLLErEREL 643
|
330 340 350
....*....|....*....|....*....|....
gi 96975038 955 LMrtgvynHEDRI---ISELDRQIREILAKSNAS 985
Cdd:PRK04863 644 TV------ERDELaarKQALDEEIERLSQPGGSE 671
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
639-913 |
3.92e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.88 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALEL--EMWKEMQEDIFENQLKQKELA-HMQALAE-EWKKRDRERESLVKKKVAEYTILEGKLQK 714
Cdd:pfam05557 125 LELQSTNSELEELQERLDLlkAKASEAEQLRQNLEKQQSSLAeAEQRIKElEFEIQSQEQDSEIVKNSKSELARIPELEK 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 715 TLIDLEKR--------------EQQLASVESELQREKK------ELQSERQRNLQELQDSIRRAKEDCIHQV--ELERLK 772
Cdd:pfam05557 205 ELERLREHnkhlnenienklllKEEVEDLKRKLEREEKyreeaaTLELEKEKLEQELQSWVKLAQDTGLNLRspEDLSRR 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 773 IKQLEEDKHRLQQQLNDAENKYKILEK---EFQQFKDQQNNKPE-------------IRLQSEINLLTLEKVELERKLES 836
Cdd:pfam05557 285 IEQLQQREIVLKEENSSLTSSARQLEKarrELEQELAQYLKKIEdlnkklkrhkalvRRLQRRVLLLTKERDGYRAILES 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 837 ATK--SKLHYKQQWGRALKELARLKQREQ---ESQMARLKKQQEELEQMRLRYLAAE-----------------EKDTVK 894
Cdd:pfam05557 365 YDKelTMSNYSPQLLERIEEAEDMTQKMQahnEEMEAQLSVAEEELGGYKQQAQTLErelqalrqqesladpsySKEEVD 444
|
330
....*....|....*....
gi 96975038 895 TERQELLDIRNELNRLRQQ 913
Cdd:pfam05557 445 SLRRKLETLELERQRLREQ 463
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
646-977 |
3.97e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.18 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 646 RETLEyKAALELEMWKEMQEDIFEnqLKQkELAHMQALAEEwkkRDRERESLvKKKVAEytilegkLQKTLIDLEKREQQ 725
Cdd:PRK02224 233 RETRD-EADEVLEEHEERREELET--LEA-EIEDLRETIAE---TEREREEL-AEEVRD-------LRERLEELEEERDD 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 726 LASvESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFqqfk 805
Cdd:PRK02224 298 LLA-EAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESEL---- 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 806 dqQNNKPEIRLQSEinlltlEKVELERKLESATKSKLHYKQQWGRA-------LKELARLKQREQESQmARLKKQQEELE 878
Cdd:PRK02224 373 --EEAREAVEDRRE------EIEELEEEIEELRERFGDAPVDLGNAedfleelREERDELREREAELE-ATLRTARERVE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 879 QMRlRYLAA-------------EEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDyL 945
Cdd:PRK02224 444 EAE-ALLEAgkcpecgqpvegsPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERRED-L 521
|
330 340 350
....*....|....*....|....*....|..
gi 96975038 946 TRLIEERdtlmRTGVYNHEDRiISELDRQIRE 977
Cdd:PRK02224 522 EELIAER----RETIEEKRER-AEELRERAAE 548
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
677-982 |
3.99e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.10 E-value: 3.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 677 LAHMQALAEEWKKRDRERESLVK--KKVAEYTILEGKLQktlIDLEKREQQLASV-ESELQREK----------KELQSE 743
Cdd:PRK04863 289 LELRRELYTSRRQLAAEQYRLVEmaRELAELNEAESDLE---QDYQAASDHLNLVqTALRQQEKieryqadleeLEERLE 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 744 RQRNLQELQDSirrakedcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 823
Cdd:PRK04863 366 EQNEVVEEADE----------QQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCGLPDL 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 824 TLEKV-----ELERKLESATKSKLHYKQ----------QWGRALKELARL-----------KQREQESQMARLKKQQEEL 877
Cdd:PRK04863 436 TADNAedwleEFQAKEQEATEELLSLEQklsvaqaahsQFEQAYQLVRKIagevsrseawdVARELLRRLREQRHLAEQL 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 878 EQMRLRyLAAEEKDTVKTERQELLdirneLNRLRQQEQKQYQDSTEIASGKKDgpHGSVLEEgLDDYLTRLIEERDTLmr 957
Cdd:PRK04863 516 QQLRMR-LSELEQRLRQQQRAERL-----LAEFCKRLGKNLDDEDELEQLQEE--LEARLES-LSESVSEARERRMAL-- 584
|
330 340
....*....|....*....|....*
gi 96975038 958 tgvynheDRIISELDRQIREILAKS 982
Cdd:PRK04863 585 -------RQQLEQLQARIQRLAARA 602
|
|
| HlpA |
COG2825 |
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ... |
680-766 |
4.16e-03 |
|
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 39.05 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 680 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK-----TLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDS 754
Cdd:COG2825 41 GKAAQKKLEKEFKKRQAELQKLEKELQALQEKLQKeaatlSEEERQKKERELQKKQQELQRKQQEAQQDLQKRQQELLQP 120
|
90
....*....|..
gi 96975038 755 IRRAKEDCIHQV 766
Cdd:COG2825 121 ILEKIQKAIKEV 132
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
699-913 |
4.22e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 4.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 699 KKKVAEYTILEGKLQKTLIDLEKREQQ----LASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihqveleRLKIK 774
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEellaALGLPPDLSPEELLELLDRIEELQELLREAEELEE---------ELQLE 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 775 QLEEDKHRLQQQLN-DAENKYKILEKEFQQFKDQQNNKPEIRLQseinlLTLEKVELERKLESATKSKLhyKQQWGRALK 853
Cdd:COG4717 367 ELEQEIAALLAEAGvEDEEELRAALEQAEEYQELKEELEELEEQ-----LEELLGELEELLEALDEEEL--EEELEELEE 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 854 ELARLkQREQESQMARLKKQQEELEQMrlrylaaEEKDTVKTERQELLDIRNELNRLRQQ 913
Cdd:COG4717 440 ELEEL-EEELEELREELAELEAELEQL-------EEDGELAELLQELEELKAELRELAEE 491
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
685-790 |
4.67e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.50 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 685 EEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLAsvesELQREKKELQSERQRnLQELQDSIRRAKEDciH 764
Cdd:pfam13851 36 AELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLE----NYEKDKQSLKNLKAR-LKVLEKELKDLKWE--H 108
|
90 100
....*....|....*....|....*.
gi 96975038 765 QVELERLkiKQLEEDKHRLQQQLNDA 790
Cdd:pfam13851 109 EVLEQRF--EKVERERDELYDKFEAA 132
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
668-986 |
4.92e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 40.86 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 668 FENQLKQKE-LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVEselqrEKKELQSERQR 746
Cdd:pfam05483 211 LEMHFKLKEdHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLE-----EKTKLQDENLK 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 747 NLQELQDSIRRAKEDCIHQVELERLKIKQLEED---------------------------KHRL---------------- 783
Cdd:pfam05483 286 ELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDlqiatkticqlteekeaqmeelnkakaAHSFvvtefeattcsleell 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 784 ---QQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV-------------------------------- 828
Cdd:pfam05483 366 rteQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIlaedeklldekkqfekiaeelkgkeqelifll 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 829 --------ELERKLESATKSKLHYKQQWGRALKEL--ARLKQREQESQMARLKKQQEELEQ----MRLRyLAAEEKDTVK 894
Cdd:pfam05483 446 qarekeihDLEIQLTAIKTSEEHYLKEVEDLKTELekEKLKNIELTAHCDKLLLENKELTQeasdMTLE-LKKHQEDIIN 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 895 TERQE-------------LLDIRNELNRLRqQEQKQYQDSTEIASGKKDGPHGSVLEEGL-DDYLTRLIEERDTLMRTGV 960
Cdd:pfam05483 525 CKKQEermlkqienleekEMNLRDELESVR-EEFIQKGDEVKCKLDKSEENARSIEYEVLkKEKQMKILENKCNNLKKQI 603
|
410 420
....*....|....*....|....*.
gi 96975038 961 YNhEDRIISELDRQIREILAKSNASN 986
Cdd:pfam05483 604 EN-KNKNIEELHQENKALKKKGSAEN 628
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
661-933 |
5.18e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 40.83 E-value: 5.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 661 KEMQEDIFENQLKQKELAHMQALAEEWK-KRDRERESLVKKKVAEYtilegKLQKTLIDLEKreqqlasveSELQREKKE 739
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREKKLRETEEvEFSLKAEVLIQKFGRSL-----KAKKRFSLLKK---------ETIYLQSAQ 875
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 740 LQSERQRNLQELQDSIRRAKEDCIHQVELERLKI---KQLEEDkhrLQQQLNDAENKYKILEK-------EFQQFKDQQN 809
Cdd:COG5022 876 RVELAERQLQELKIDVKSISSLKLVNLELESEIIelkKSLSSD---LIENLEFKTELIARLKKllnnidlEEGPSIEYVK 952
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 810 NKPEIRLQSEINLLTLEKVELERKLESATKSKLHYK------QQWGRALKELARLKQREQESqmarlKKQQEELEQMRLR 883
Cdd:COG5022 953 LPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNkanselKNFKKELAELSKQYGALQES-----TKQLKELPVEVAE 1027
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 96975038 884 YLAAEEKD-TVKTERQELLDIRnELNRLRQQEQKQYQDSTEIASGKKDGPH 933
Cdd:COG5022 1028 LQSASKIIsSESTELSILKPLQ-KLKGLLLLENNQLQARYKALKLRRENSL 1077
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
639-919 |
5.45e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.26 E-value: 5.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEwKKRDRERESLVKKKVAEYTILEGKLQKtlid 718
Cdd:pfam07888 80 SRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAH-EARIRELEEDIKTLTQRVLERETELER---- 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 719 LEKREQQLASVESELQREKKELQS------------------------ERQRNLQELQDSIRR--AKEDCIHQVELErlk 772
Cdd:pfam07888 155 MKERAKKAGAQRKEEEAERKQLQAklqqteeelrslskefqelrnslaQRDTQVLQLQDTITTltQKLTTAHRKEAE--- 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 773 IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGR-- 850
Cdd:pfam07888 232 NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRD-----RTQAELHQARLQAAQLTLQLADASLALREGRARWAQer 306
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 96975038 851 ------ALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDT----VKTERQELLDIRNELnRLRQQEQKQYQ 919
Cdd:pfam07888 307 etlqqsAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKDCnrvqLSESRRELQELKASL-RVAQKEKEQLQ 384
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
678-899 |
5.49e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 678 AHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESE---LQREKKELQSERQRNLQELQDS 754
Cdd:COG3883 12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEidkLQAEIAEAEAEIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 755 IRRAKEDCIHQVELER-LKIKQLEEDKHRLQ--QQLNDAENkyKILEkEFQQFKDQQNNKpEIRLQSEINLLTLEKVELE 831
Cdd:COG3883 92 ARALYRSGGSVSYLDVlLGSESFSDFLDRLSalSKIADADA--DLLE-ELKADKAELEAK-KAELEAKLAELEALKAELE 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 96975038 832 RKLESATKSKlhyKQQwgRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQE 899
Cdd:COG3883 168 AAKAELEAQQ---AEQ--EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| COG5644 |
COG5644 |
U3 small nucleolar RNA-associated protein 14 [Function unknown]; |
628-943 |
5.50e-03 |
|
U3 small nucleolar RNA-associated protein 14 [Function unknown];
Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 40.84 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 628 KPSSLPPAPCPSEIQTEPRETLEYKaaleleMWKEMQEDIFENQ---LKQKELAHMQALAEEWKKRDRE---------RE 695
Cdd:COG5644 315 ETARPVPSNNGLASSFEPRTESERK------MHQALLDAGLENEsalKKQEELALNKLSVEEVAERTRQlrfmrelmfRE 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 696 SLVKKKVAEytILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihqvELERLkiKQ 775
Cdd:COG5644 389 ERKAKRVAK--IKSKTYRKIRKNRKEKEMALIPKSEDLENEKSEEARALERMTQRHKNTSSWTRK------MLERA--SH 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 776 LEEDKHRLQQQLNDAEN-KYKILEKEFQQFKDqqnnkpeIRLQSEINLLTLEKVELERKlesATKSKLHYKQQWGRALKE 854
Cdd:COG5644 459 GEGTREAVNEQIRKGDElMQRIHGKEIMDGED-------VSEFSDSDYDTNEQVSTAFE---KIRNEEELKGVLGMKFMR 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 855 LARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTV--KTERQELLDIRNELNRL--RQQEQKQYQDST-------E 923
Cdd:COG5644 529 DASNRQMAASKISVADLVKVENGDDIDVGELDEVGGDAIyaNAGRREVFPVVEQRRKLapRKRKEDFVTPSTsleksmdR 608
|
330 340
....*....|....*....|
gi 96975038 924 IASGKKDGPHGSVLEEGLDD 943
Cdd:COG5644 609 ILHGQKKRAEGAVVFEKPLE 628
|
|
| F-BAR_PACSIN |
cd07655 |
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein ... |
739-917 |
5.70e-03 |
|
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons (PACSIN) proteins; F-BAR domains are dimerization modules that bind and bend membranes and are found in proteins involved in membrane dynamics and actin reorganization. Protein kinase C and Casein kinase Substrate in Neurons (PACSIN) proteins, also called Synaptic dynamin-associated proteins (Syndapins), act as regulators of cytoskeletal and membrane dynamics. They bind both dynamin and Wiskott-Aldrich syndrome protein (WASP), and may provide direct links between the actin cytoskeletal machinery through WASP and dynamin-dependent endocytosis. Vetebrates harbor three isoforms with distinct expression patterns and specific functions. PACSINs contain an N-terminal F-BAR domain and a C-terminal SH3 domain. F-BAR domains form banana-shaped dimers with a positively-charged concave surface that binds to negatively-charged lipid membranes. They can induce membrane deformation in the form of long tubules.
Pssm-ID: 153339 [Multi-domain] Cd Length: 258 Bit Score: 39.60 E-value: 5.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 739 ELQSERQRNLQ-ELQDSIRRAKEDCIHQVELERLK-IKQLEEDKHRLQQQ-------LNDAENKYKILEKEFQQFKDQQN 809
Cdd:cd07655 78 ELHLSIRDKLLnDVVEEVKTWQKENYHKSMMGGFKeTKEAEDGFAKAQKPwakllkkVEKAKKAYHAACKAEKSAQKQEN 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 810 NKpeirlQSEINLLTlEKV-ELERKLESATKSKLHYKQQWGRALKELARLKQREQESqMARLKKQQEELEQMRLRYLaae 888
Cdd:cd07655 158 NA-----KSDTSLSP-DQVkKLQDKVEKCKQEVSKTKDKYEKALEDLNKYNPRYMED-MEQVFDKCQEFEEKRLDFF--- 227
|
170 180
....*....|....*....|....*....
gi 96975038 889 ekdtvkteRQELLDIRNELNRLRQQEQKQ 917
Cdd:cd07655 228 --------KEILLSYHRHLDLSTNPSFKA 248
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
680-832 |
6.34e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 39.79 E-value: 6.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 680 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAK 759
Cdd:pfam15905 154 MSSLSMELMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSC 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 760 EdcIHQVELERLKIKQLEED------------------KHRLQQQLNDAENKYKILEKEFQQfKDQQNNKPEIRLQSEIN 821
Cdd:pfam15905 234 V--SEQVEKYKLDIAQLEELlkekndeieslkqsleekEQELSKQIKDLNEKCKLLESEKEE-LLREYEEKEQTLNAELE 310
|
170
....*....|.
gi 96975038 822 LLTlEKVELER 832
Cdd:pfam15905 311 ELK-EKLTLEE 320
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
732-913 |
7.06e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 39.51 E-value: 7.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 732 ELQREKKELQSERQRNLQELQDSIRRAKEdcihqvelERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNk 811
Cdd:COG1340 12 ELEEKIEELREEIEELKEKRDELNEELKE--------LAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 812 peirLQSEINLLTLEKVELERKLESATKSKLHYKQqwgrALKELARLKQREQES------------QMARLKKQQEELEQ 879
Cdd:COG1340 83 ----LNEKLNELREELDELRKELAELNKAGGSIDK----LRKEIERLEWRQQTEvlspeeekelveKIKELEKELEKAKK 154
|
170 180 190
....*....|....*....|....*....|....
gi 96975038 880 MRlrylaaEEKDTVKTERQELLDIRNELNRLRQQ 913
Cdd:COG1340 155 AL------EKNEKLKELRAELKELRKEAEEIHKK 182
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
733-978 |
7.56e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 39.52 E-value: 7.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 733 LQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAenkyKILEKEFQQ-FKDQQNNK 811
Cdd:pfam00038 23 LEQQNKLLETKISELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTVERARLQLELDNL----RLAAEDFRQkYEDELNLR 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 812 PEirLQSEINLL-------TLEKVELERKLESATKS-----KLH-----------------------YKQQWGRALKELa 856
Cdd:pfam00038 99 TS--AENDLVGLrkdldeaTLARVDLEAKIESLKEElaflkKNHeeevrelqaqvsdtqvnvemdaaRKLDLTSALAEI- 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 857 rlkqREQ-ESQMARLKKQQEELEQMRLRYL---AAEEKDTVKTERQELLDIRNELNRLrqqeqkqyqdSTEIASGKKdgp 932
Cdd:pfam00038 176 ----RAQyEEIAAKNREEAEEWYQSKLEELqqaAARNGDALRSAKEEITELRRTIQSL----------EIELQSLKK--- 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 96975038 933 hgsvLEEGLDDYLTRLiEERDTLMRTGVynheDRIISELDRQIREI 978
Cdd:pfam00038 239 ----QKASLERQLAET-EERYELQLADY----QELISELEAELQET 275
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
653-882 |
8.49e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 40.32 E-value: 8.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 653 AALELEMWKEMQEDIFENQLkqkELAHMQALAEEWKKRDRERESLVKKKVAEYTILEG-----KLQKTLIDLEKREQQLA 727
Cdd:COG3096 439 AEDYLAAFRAKEQQATEEVL---ELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAwqtarELLRRYRSQQALAQRLQ 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 728 SVESELQREKKELqsERQRNLQELQDSI-RRAKEDCIHQVELERLKiKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD 806
Cdd:COG3096 516 QLRAQLAELEQRL--RQQQNAERLLEEFcQRIGQQLDAAEELEELL-AELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 96975038 807 QQNnkpEIRLQSEINLLTLEKVElerKLESATKSKLHYKQQWGRALKELA-RLKQREQESQMARLKKQQEELEQMRL 882
Cdd:COG3096 593 RIK---ELAARAPAWLAAQDALE---RLREQSGEALADSQEVTAAMQQLLeREREATVERDELAARKQALESQIERL 663
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
702-913 |
8.77e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 39.88 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 702 VAEYTILEGKLQKTLIDLEKREQQLA---SVESELQREKKELQSERQ-------------RNLQELQDSIRRAKEDC--- 762
Cdd:PRK01156 182 ISNIDYLEEKLKSSNLELENIKKQIAddeKSHSITLKEIERLSIEYNnamddynnlksalNELSSLEDMKNRYESEIkta 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 763 ---IHQVELERLKIKQLEEdkhRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEI--RLQSEINlltlEKVELERKLESA 837
Cdd:PRK01156 262 esdLSMELEKNNYYKELEE---RHMKIINDPVYKNRNYINDYFKYKNDIENKKQIlsNIDAEIN----KYHAIIKKLSVL 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 838 TKSKLHY---KQQWGRALKELARLKQREQESQMA-------RLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNEL 907
Cdd:PRK01156 335 QKDYNDYikkKSRYDDLNNQILELEGYEMDYNSYlksieslKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEI 414
|
....*.
gi 96975038 908 NRLRQQ 913
Cdd:PRK01156 415 NVKLQD 420
|
|
| OmpH |
pfam03938 |
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ... |
680-758 |
8.86e-03 |
|
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.
Pssm-ID: 461098 [Multi-domain] Cd Length: 140 Bit Score: 37.56 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 96975038 680 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREK----KELQSERQRNLQELQDSI 755
Cdd:pfam03938 21 QAQLEKKFKKRQAELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLQqkaqQELQKKQQELLQPIQDKI 100
|
...
gi 96975038 756 RRA 758
Cdd:pfam03938 101 NKA 103
|
|
| |
