|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
35-454 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 746.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 115 KNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFSS 194
Cdd:pfam00709 81 ELEERGI-DVPDRLFISDRAHLILPYHKALDGLRE---EARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFRE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 195 RFKNLAHQHQSMFPTL---EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFVT 271
Cdd:pfam00709 156 KLEALLELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEG-KKILFEGAQGTLLDIDHGTYPYVT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAH 351
Cdd:pfam00709 235 SSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 352 MVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIR 431
Cdd:pfam00709 315 RINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVE 394
|
410 420
....*....|....*....|...
gi 22748717 432 FVENHVGVAVKWVGVGKSRESMI 454
Cdd:pfam00709 395 FIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
33-454 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 673.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 113 AEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDglqevqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEF 192
Cdd:smart00788 81 IEELEAKGV-DVKDRLFISDRAHLILPYHIALD-------KAREKARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEEVL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 193 SSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYP 268
Cdd:smart00788 152 REKLEELLDYKNFLLKKLygaePVDVEEILEELLEYAERLRPYVTDVSELLNEALKAG-KKVLFEGAQGTLLDIDHGTYP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 269 FVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILR 348
Cdd:smart00788 231 YVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 349 YAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQN 428
Cdd:smart00788 311 YAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKK 390
|
410 420
....*....|....*....|....*.
gi 22748717 429 YIRFVENHVGVAVKWVGVGKSRESMI 454
Cdd:smart00788 391 YIERIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
30-454 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 635.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 30 GSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL 109
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 110 FEEAEKNEKKGlKDWEKRLIISDRAHLVFDFHQAVDGLQEvQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDF 189
Cdd:PTZ00350 91 LEEIEQLTKKG-INLLGRLYISDRAHLVFDLHQAIDGIQE-SEKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-NF 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 190 DEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYPF 269
Cdd:PTZ00350 168 ETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIK-EGKRVLVEGANATMLDIDFGTYPY 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 270 VTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRY 349
Cdd:PTZ00350 247 VTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 350 AHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGK--RIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 427
Cdd:PTZ00350 327 VQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQ 406
|
410 420
....*....|....*....|....*..
gi 22748717 428 NYIRFVENHVGVAVKWVGVGKSRESMI 454
Cdd:PTZ00350 407 KYVLFIEELLGVPIVWIGVGPNRENMI 433
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
33-456 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 627.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 113 AEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEF 192
Cdd:COG0104 81 IDGLEARGV-DVRSRLRISERAHLILPYHRALDKARE---EARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEVL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 193 SSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALH-GppKKILVEGANAALLDIDFGTY 267
Cdd:COG0104 156 REKLEELLEYKNFLLEKLygaePLDFEELLEEYLEYAERLKPYVADTSELLNEALKaG--KKVLFEGAQGTLLDIDHGTY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 268 PFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMIL 347
Cdd:COG0104 234 PYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVAL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 348 RYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 427
Cdd:COG0104 314 RYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENAR 393
|
410 420
....*....|....*....|....*....
gi 22748717 428 NYIRFVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:COG0104 394 AYVERIEELLGVPISIVSVGPDREQTIVR 422
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
32-454 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 529.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 32 RVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFE 111
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 112 EAEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQaqeGKNIGTTKKGIGPTYSSKAARTGLRICDllsdfde 191
Cdd:cd03108 81 EIEELEKKGI-DVKGRLLISDRAHLVFPYHQELDGLEEKERG---GKKIGTTKRGIGPAYADKAARTGIRVGD------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 192 fssrfknlahqhqsmfptleidiegqlkrlkgfaerirPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYPFVT 271
Cdd:cd03108 150 --------------------------------------PYVVDTVELLNEALK-AGKKVLFEGAQGTLLDIDFGTYPYVT 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAH 351
Cdd:cd03108 191 SSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAV 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 352 MVNGFTALALTKLDIldvlgevkvgvsyklngkripyfpanqemlqkveveyetlpgwkadttgarrwedlppQAQNYIR 431
Cdd:cd03108 271 RINGLTELALTKLDV----------------------------------------------------------NAQKYIE 292
|
410 420
....*....|....*....|...
gi 22748717 432 FVENHVGVAVKWVGVGKSRESMI 454
Cdd:cd03108 293 RIEELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
35-456 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 512.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 115 KNEKkGLKDWEKRLIISDRAHLVFDFHQAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD---FDE 191
Cdd:TIGR00184 81 YLEK-RGISVRDRLFVSYRCHLILPYHKKLDKARE---KSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDeafAEK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 192 FSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFVT 271
Cdd:TIGR00184 157 AKNILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEG-EKVLFEGAQGTMLDIDYGTYPYVT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAH 351
Cdd:TIGR00184 236 SSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYAC 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 352 MVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIR 431
Cdd:TIGR00184 316 RLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIE 395
|
410 420
....*....|....*....|....*
gi 22748717 432 FVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:TIGR00184 396 RIEELTGVPVTIISTGPEREQTIDL 420
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
33-355 |
5.19e-27 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 109.77 E-value: 5.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQ-GGNNAGHTVVVD-GKEYDFHLLPSGI-INTKAVSFIGNGVVIHLPGL 109
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDeGRKFVHRMLPNGIvSPPLKQVLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 110 FEEAEKNEKKGLkDWEKRLIISDRAHLvfdfhqaVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTglricdllsdf 189
Cdd:NF038379 81 REEIEELEDAGH-DVGKRLLIHEQATV-------IELHKHVEEEAGPMTKIGSTKKGIGAARAAKIRRN----------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 190 defssrfknlahqhqsmfPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPF 269
Cdd:NF038379 142 ------------------PSTLGDAEGDFGEGAVRDQPWEIAERVVDNALYDFALQAAERIQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 270 VTSSNCTVGGVCTGLGIPPQNI--GDVYGVVKAYTTRVGIGAFPT---------EQIneigGLLQtrghEWGVTTGRKRR 338
Cdd:NF038379 204 CTSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGWSGNSypdqgettwEEL----GLPE----ELTTVTKKVRR 275
|
330
....*....|....*..
gi 22748717 339 CGWLDLMILRYAHMVNG 355
Cdd:NF038379 276 VGTFSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
35-454 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 746.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 115 KNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFSS 194
Cdd:pfam00709 81 ELEERGI-DVPDRLFISDRAHLILPYHKALDGLRE---EARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFRE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 195 RFKNLAHQHQSMFPTL---EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFVT 271
Cdd:pfam00709 156 KLEALLELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEG-KKILFEGAQGTLLDIDHGTYPYVT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAH 351
Cdd:pfam00709 235 SSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 352 MVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIR 431
Cdd:pfam00709 315 RINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVE 394
|
410 420
....*....|....*....|...
gi 22748717 432 FVENHVGVAVKWVGVGKSRESMI 454
Cdd:pfam00709 395 FIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
33-454 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 673.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 113 AEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDglqevqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEF 192
Cdd:smart00788 81 IEELEAKGV-DVKDRLFISDRAHLILPYHIALD-------KAREKARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEEVL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 193 SSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYP 268
Cdd:smart00788 152 REKLEELLDYKNFLLKKLygaePVDVEEILEELLEYAERLRPYVTDVSELLNEALKAG-KKVLFEGAQGTLLDIDHGTYP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 269 FVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILR 348
Cdd:smart00788 231 YVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 349 YAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQN 428
Cdd:smart00788 311 YAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKK 390
|
410 420
....*....|....*....|....*.
gi 22748717 429 YIRFVENHVGVAVKWVGVGKSRESMI 454
Cdd:smart00788 391 YIERIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
30-454 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 635.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 30 GSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL 109
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 110 FEEAEKNEKKGlKDWEKRLIISDRAHLVFDFHQAVDGLQEvQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDF 189
Cdd:PTZ00350 91 LEEIEQLTKKG-INLLGRLYISDRAHLVFDLHQAIDGIQE-SEKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-NF 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 190 DEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYPF 269
Cdd:PTZ00350 168 ETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIK-EGKRVLVEGANATMLDIDFGTYPY 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 270 VTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRY 349
Cdd:PTZ00350 247 VTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 350 AHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGK--RIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 427
Cdd:PTZ00350 327 VQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQ 406
|
410 420
....*....|....*....|....*..
gi 22748717 428 NYIRFVENHVGVAVKWVGVGKSRESMI 454
Cdd:PTZ00350 407 KYVLFIEELLGVPIVWIGVGPNRENMI 433
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
33-456 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 627.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 113 AEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEF 192
Cdd:COG0104 81 IDGLEARGV-DVRSRLRISERAHLILPYHRALDKARE---EARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEVL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 193 SSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALH-GppKKILVEGANAALLDIDFGTY 267
Cdd:COG0104 156 REKLEELLEYKNFLLEKLygaePLDFEELLEEYLEYAERLKPYVADTSELLNEALKaG--KKVLFEGAQGTLLDIDHGTY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 268 PFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMIL 347
Cdd:COG0104 234 PYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVAL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 348 RYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 427
Cdd:COG0104 314 RYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENAR 393
|
410 420
....*....|....*....|....*....
gi 22748717 428 NYIRFVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:COG0104 394 AYVERIEELLGVPISIVSVGPDREQTIVR 422
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
32-456 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 612.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 32 RVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFE 111
Cdd:PRK01117 2 KNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 112 EAEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEVQRqaqeGKN-IGTTKKGIGPTYSSKAARTGLRICDLLsDFD 190
Cdd:PRK01117 82 EIDELEARGV-DVRERLRISERAHLILPYHRALDKAREKAR----GKKkIGTTGRGIGPAYEDKVARRGIRVGDLL-DPE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 191 EFSSRFKNLAHQH----QSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALH-GppKKILVEGANAALLDIDFG 265
Cdd:PRK01117 156 TFAEKLEENLEYKnfllTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKaG--KRVLFEGAQGTLLDIDHG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 266 TYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLM 345
Cdd:PRK01117 234 TYPFVTSSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 346 ILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQ 425
Cdd:PRK01117 314 ALRYAVRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPEN 393
|
410 420 430
....*....|....*....|....*....|.
gi 22748717 426 AQNYIRFVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:PRK01117 394 ARKYIKRIEELTGVPISIISTGPDRDQTIIL 424
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
31-454 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 597.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 31 SRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVV-VDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL 109
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 110 FEEAEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEVQRqaqEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDF 189
Cdd:PLN02513 82 FEEIDGLESNGV-SCEGRLLVSDRAHLLFDFHQEVDGLREAEL---AGSKIGTTKRGIGPAYSSKATRNGLRVGDLR-HM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 190 DEFSSRFKNLAHQHQSMFPTLEID---IEGQLKRLKGFAERIRPMVRDGVYFMYEAlHGPPKKILVEGANAALLDIDFGT 266
Cdd:PLN02513 157 DTFAEKLRELLADAAARFEGFEYDasmVEEEVEAYKKFAERLEPFITDTVHYLNEA-IQAGKKILVEGAQATMLDIDFGT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 267 YPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMI 346
Cdd:PLN02513 236 YPFVTSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 347 LRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKL-NGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQ 425
Cdd:PLN02513 316 LKYSCQINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAA 395
|
410 420
....*....|....*....|....*....
gi 22748717 426 AQNYIRFVENHVGVAVKWVGVGKSRESMI 454
Cdd:PLN02513 396 AQAYVERIEELVGVPVHYIGVGPGRDALI 424
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
32-454 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 529.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 32 RVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFE 111
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 112 EAEKNEKKGLkDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQaqeGKNIGTTKKGIGPTYSSKAARTGLRICDllsdfde 191
Cdd:cd03108 81 EIEELEKKGI-DVKGRLLISDRAHLVFPYHQELDGLEEKERG---GKKIGTTKRGIGPAYADKAARTGIRVGD------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 192 fssrfknlahqhqsmfptleidiegqlkrlkgfaerirPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYPFVT 271
Cdd:cd03108 150 --------------------------------------PYVVDTVELLNEALK-AGKKVLFEGAQGTLLDIDFGTYPYVT 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAH 351
Cdd:cd03108 191 SSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAV 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 352 MVNGFTALALTKLDIldvlgevkvgvsyklngkripyfpanqemlqkveveyetlpgwkadttgarrwedlppQAQNYIR 431
Cdd:cd03108 271 RINGLTELALTKLDV----------------------------------------------------------NAQKYIE 292
|
410 420
....*....|....*....|...
gi 22748717 432 FVENHVGVAVKWVGVGKSRESMI 454
Cdd:cd03108 293 RIEELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
35-456 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 512.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 115 KNEKkGLKDWEKRLIISDRAHLVFDFHQAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD---FDE 191
Cdd:TIGR00184 81 YLEK-RGISVRDRLFVSYRCHLILPYHKKLDKARE---KSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDeafAEK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 192 FSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFVT 271
Cdd:TIGR00184 157 AKNILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEG-EKVLFEGAQGTMLDIDYGTYPYVT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAH 351
Cdd:TIGR00184 236 SSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYAC 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 352 MVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIR 431
Cdd:TIGR00184 316 RLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIE 395
|
410 420
....*....|....*....|....*
gi 22748717 432 FVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:TIGR00184 396 RIEELTGVPVTIISTGPEREQTIDL 420
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
34-456 |
4.37e-128 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 377.76 E-value: 4.37e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 34 TVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEA 113
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEEC 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 114 EKNEKKGLKDWEKrLIISDRAHLVFDFHQAVDGLQEVQrQAQEGKnIGTTKKGIGPTYSSKAARTGLRICDLLSDfdEFS 193
Cdd:PRK13787 84 DRLQKEGFPVKDK-LLLSDACHLLFPYHSQIDSARETT-SSQEHK-IGTTKKGIGICYADKMMRTGLRVGDLLDK--SYK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 194 SRFKNLAH-------QHQSMFPTLEIDIEgqlKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGT 266
Cdd:PRK13787 159 RRLKHLVDeknreldKLYGMPPVSYNDIN---DGLKFFLSKVGKNIINTAYYLDTELK-KGKRVLLEGAQGTGLDVDFGT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 267 YPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMI 346
Cdd:PRK13787 235 YPYVTSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEM 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 347 LRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPAnqEMLQKVEVEYETLPGWKADTTGARRWEDLPPQA 426
Cdd:PRK13787 315 LKHSVRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPS--QGLEKVEPLYEEFPGWKDDISGINEFQKLPEKC 392
|
410 420 430
....*....|....*....|....*....|
gi 22748717 427 QNYIRFVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:PRK13787 393 KNYISALEKWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
34-455 |
3.01e-120 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 357.57 E-value: 3.01e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 34 TVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVsFIGNGVVIHLPGLFEEA 113
Cdd:PRK13786 3 TIITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 114 EKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQegknIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFS 193
Cdd:PRK13786 82 DMLEKHGVKVDAEKLGIDAKTSIIMPYHIELDGLRESARTEK----IGTTKRGIGFAYIDKIARDEVRMSDLV-DKERLM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 194 SRFKNLAHQHQSMFPTLEIDI-----EGQLKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYP 268
Cdd:PRK13786 157 RRLEELAPQKEKEIKELGGDPsivrdEALIDKYLELGRQLAPYITDVSYEINKALD-EGKSVLAEGAQGTHLDVIHGTQK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 269 FVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILR 348
Cdd:PRK13786 236 FVTSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 349 YAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQN 428
Cdd:PRK13786 316 KAIYLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARN 395
|
410 420
....*....|....*....|....*..
gi 22748717 429 YIRFVENHVGVAVKWVGVGKSRESMIQ 455
Cdd:PRK13786 396 YVERLEELMGVPIKYISVGPGREQTFK 422
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
35-456 |
3.12e-119 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 354.41 E-value: 3.12e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 115 KNEKKGlKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRqaqeGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDfDEFSS 194
Cdd:PRK13783 84 ELKEKF-PDYSGRIFISELAHVVLPVHKELDEIIESVR----KNAIGTTKRGIGPAYADKVMRVGVRLADLFDE-EKLRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 195 RFKNLAHQHQSMFpTLEIDIEGQLKRLKGFAERIRPMVRDGVYfMYEALHGppKKILVEGANAALLDIDFGTYPFVTSSN 274
Cdd:PRK13783 158 FLEKILSLYKKLY-GIEFDVEKMMEDLLTFYEKIKDLVVSPVE-IKRILEE--KSVLFEGTQGVLLDLDVGTYPYVTSSN 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 275 CTVGGVCTGLGIPPQnIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVN 354
Cdd:PRK13783 234 CSTTGVSAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVS 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 355 GFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYfPANQEMLQKVEVEYETLPGWKadTTGARRWEDlppqaqnYIRFVE 434
Cdd:PRK13783 313 GVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWK--SLEDKNFLK-------FVDFIE 382
|
410 420
....*....|....*....|..
gi 22748717 435 NHVGVAVKWVGVGKSRESMIQL 456
Cdd:PRK13783 383 RETGRKIAYISTGPKIEEIVEV 404
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
36-451 |
9.12e-117 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 347.95 E-value: 9.12e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 36 VLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEK 115
Cdd:PRK13788 6 IIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAEEREN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 116 NEKKGLkdwEKRLIISDRAHLVFDFHQAVDGlqevqrqaqeGKN-IGTTKKGIGPTYSSKAARTGLRICDLLSD--FDEF 192
Cdd:PRK13788 86 LRAGGL---NPKLLISERAHLVLPHHKYVDG----------RKNfVGTTGRGIGPAYSDRARRVGIRFGDLLDEavLRER 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 193 SSRFknLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEAL-HGppKKILVEGANAALLDIDFGTYPFVT 271
Cdd:PRK13788 153 VERL--LEAKPNSTREAGWDTVEKALADLAPMREILLPFIADTGSLLREAIrEG--KRVLFEGAQATLLDLNYGTYPYVT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 272 SSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRG----HEWGVTTGRKRRCGWLDLMIL 347
Cdd:PRK13788 229 SSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 348 RYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKripyfpanqemlqkveVEYETLPGWkADTTGARRWEDLPPQAQ 427
Cdd:PRK13788 309 KYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDGQ----------------PVYKELPGW-GDLDGVKSREALPKEAQ 371
|
410 420
....*....|....*....|....
gi 22748717 428 NYIRFVENHVGVAVKWVGVGKSRE 451
Cdd:PRK13788 372 AYLELIEETTGVPVVMFSTSPRRE 395
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
33-456 |
9.59e-109 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 329.03 E-value: 9.59e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVlGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKaVSFIGNGVVIHLPGLFEE 112
Cdd:PRK13785 3 VTIV-GSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGK-IGVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 113 AEKNEKKGLkDWEKRliISDRAHLVFDFHQAVDGLQEvQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEF 192
Cdd:PRK13785 81 IDALRERGL-DPDVR--VAERAHVILPYHRVLDGIEE-EAKSDSDLEVGTTGRGIGPTYEDKAGRRGVRVGDLL-DPDVL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 193 SSRFKNLAHQHQSMFPTL----------EIDIEGQLKRLKGFAERIRP--MVRDGVYFMYEALHGPpKKILVEGANAALL 260
Cdd:PRK13785 156 RDRLEYVVPQKRALAEDVygldasetpeAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDG-DNVMLEGAQGTSI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 261 DIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGD--VYGVVKAYTTRVGIGAFPTE---------------QINEIGGLLQ 323
Cdd:PRK13785 235 DIDHGNYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTElggvegdtpdeggrpDEEELATYIR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 324 TRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEY 403
Cdd:PRK13785 315 EEGGEYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNF 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 22748717 404 ETLPGWKA---DTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:PRK13785 395 RSFDGWPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVL 450
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
35-454 |
1.03e-93 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 289.61 E-value: 1.03e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEEIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 115 KNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLqevqRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFSS 194
Cdd:PRK13784 85 RLQAKGIAISAENLFVSESCTIITSYHKLLDAV----RESNTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLF-DKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 195 RFKNLAHQHQSMF--------PTLEIDIEgqlkRLKGFAERIRPMVRDGVYFMYEALhGPPKKILVEGANAALLDIDFGT 266
Cdd:PRK13784 160 RLAISLAEKETLFrdlykveyPTLEQEFD----KLFALGQKLKQYAADTFSIIDQAI-AAGKNVVYEGAQGVLLDVDYGT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 267 YPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMI 346
Cdd:PRK13784 235 YPFVTSSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPL 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 347 LRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIpYFPANQEMLQKVEVEYETLPGWKADTTGARrwEDLPPQA 426
Cdd:PRK13784 315 LKYSAKCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEI-YCAYPGIDLYKVEPILVEMEPFSIDETVTK--DNMPAAL 391
|
410 420
....*....|....*....|....*...
gi 22748717 427 QNYIRFVENHVGVAVKWVGVGKSRESMI 454
Cdd:PRK13784 392 KTYLKTIENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
33-456 |
5.11e-64 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 209.74 E-value: 5.11e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLA-TD-ADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLF 110
Cdd:PRK04293 3 CTIVVGGFFGDEGKGKIIAYLAlKDkPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 111 EEAEKNEKKGlkdwekRLIISDRAHLVFDFHQAVDglqevQRQAQEGKNIGTTKKGIGPTYSSKAARTGlricDLLSDFD 190
Cdd:PRK04293 83 KEVEELNVGG------RVFVDYRCGIIEEKHVEED-----RSDEHLSKKIGSTGTGCGPANADRVLRRL----KLAKDVE 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 191 EfssrfknlahqhqsmfptleidiegqlkrlkgfaerIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFV 270
Cdd:PRK04293 148 E------------------------------------LEKYLTDVPEEVNEALDRG-ENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 271 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGgllQTRG-HEWGVTTGRKRRCGWLDLMILRY 349
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEA---EKLGlVEYGTVTGRRRRVGPFDFELARR 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 350 AHMVNGFTALALTKLDILDvlgevkvgvsyklngkripyfpanqemlqkveveyetlpgwkADTTGARRWEDLPPQAQNY 429
Cdd:PRK04293 268 AARINGATQIAITKLDKLD------------------------------------------KEAYGVTEYDKLPPEAKKF 305
|
410 420
....*....|....*....|....*..
gi 22748717 430 IRFVENHVGVAVKWVGVGKSRESMIQL 456
Cdd:PRK04293 306 IEEIEEELGVPVTLISTGPELEDTIDL 332
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
33-355 |
5.19e-27 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 109.77 E-value: 5.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQ-GGNNAGHTVVVD-GKEYDFHLLPSGI-INTKAVSFIGNGVVIHLPGL 109
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDeGRKFVHRMLPNGIvSPPLKQVLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 110 FEEAEKNEKKGLkDWEKRLIISDRAHLvfdfhqaVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTglricdllsdf 189
Cdd:NF038379 81 REEIEELEDAGH-DVGKRLLIHEQATV-------IELHKHVEEEAGPMTKIGSTKKGIGAARAAKIRRN----------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 190 defssrfknlahqhqsmfPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYPF 269
Cdd:NF038379 142 ------------------PSTLGDAEGDFGEGAVRDQPWEIAERVVDNALYDFALQAAERIQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 270 VTSSNCTVGGVCTGLGIPPQNI--GDVYGVVKAYTTRVGIGAFPT---------EQIneigGLLQtrghEWGVTTGRKRR 338
Cdd:NF038379 204 CTSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGWSGNSypdqgettwEEL----GLPE----ELTTVTKKVRR 275
|
330
....*....|....*..
gi 22748717 339 CGWLDLMILRYAHMVNG 355
Cdd:NF038379 276 VGTFSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
33-197 |
8.57e-13 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 70.47 E-value: 8.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 33 VTVVLGAQWGDEGKGKVVDLLATD--ADIISRCQGGNNAGHTVVVD-GKEYDFHLLPSGIINTKAVSFIGNGVVIHlPGL 109
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMD-PVS 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748717 110 FEEAEKNE--KKGLkDWEKRLIISDRAhLVFDFHQAVDGLQEVQRQaqegknigTTKKGIGPTYSSKAARTGLRICDLLS 187
Cdd:PTZ00351 250 FMEKEIIQliDAGI-DYRDRLFIGNVC-IVTPYHKLLDLLGSAANS--------STLKGMAPVHGSKVMKRGIRLDHIFN 319
|
170
....*....|
gi 22748717 188 DFDEFSSRFK 197
Cdd:PTZ00351 320 DDETLRKRLE 329
|
|
| |
