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Conserved domains on  [gi|24308245|ref|NP_689521|]
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recQ-mediated genome instability protein 2 [Homo sapiens]

Protein Classification

RMI2 domain-containing protein( domain architecture ID 11240914)

RMI2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RMI2 pfam16100
RecQ-mediated genome instability protein 2; RMI2 is a eukaryotic family of an OB3, ...
 21-143 1.11e-60

RecQ-mediated genome instability protein 2; RMI2 is a eukaryotic family of an OB3, oligo-nucleotide-binding proteins. It is an essential component of the RMI complex that plays a vital role in the processing of homologous recombination intermediates in order to limit DNA-crossover-formation in cells.


:

Pssm-ID: 465022  Cd Length: 128  Bit Score: 183.31  E-value: 1.11e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24308245    21 PPLKVLAEQLR---RDAEGGPGAWRLSRAAAGRGpLDLAAVWMQGRVVMADRGE---ARLRDPSGDFSVRGLERVPRGRP 94
Cdd:pfam16100   1 PALKLFCSQLRtaaDAGSGGAATLRVVRLSIGGG-LLFQRVWLQGTVVEVDNSGddsFLLDDGTGVFTVTGLNELPLGRP 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 24308245    95 CLVPGKYVMVMGVVQACSPEPCLQAVKMTDLSDNPIHESMWELEVEDLH 143
Cdd:pfam16100  80 CLKEGMYVMVVGVIQACSPEPVLRAVKMTDLSDNPDREAMWYLEVEELQ 128
 
Name Accession Description Interval E-value
RMI2 pfam16100
RecQ-mediated genome instability protein 2; RMI2 is a eukaryotic family of an OB3, ...
 21-143 1.11e-60

RecQ-mediated genome instability protein 2; RMI2 is a eukaryotic family of an OB3, oligo-nucleotide-binding proteins. It is an essential component of the RMI complex that plays a vital role in the processing of homologous recombination intermediates in order to limit DNA-crossover-formation in cells.


Pssm-ID: 465022  Cd Length: 128  Bit Score: 183.31  E-value: 1.11e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24308245    21 PPLKVLAEQLR---RDAEGGPGAWRLSRAAAGRGpLDLAAVWMQGRVVMADRGE---ARLRDPSGDFSVRGLERVPRGRP 94
Cdd:pfam16100   1 PALKLFCSQLRtaaDAGSGGAATLRVVRLSIGGG-LLFQRVWLQGTVVEVDNSGddsFLLDDGTGVFTVTGLNELPLGRP 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 24308245    95 CLVPGKYVMVMGVVQACSPEPCLQAVKMTDLSDNPIHESMWELEVEDLH 143
Cdd:pfam16100  80 CLKEGMYVMVVGVIQACSPEPVLRAVKMTDLSDNPDREAMWYLEVEELQ 128
 
Name Accession Description Interval E-value
RMI2 pfam16100
RecQ-mediated genome instability protein 2; RMI2 is a eukaryotic family of an OB3, ...
 21-143 1.11e-60

RecQ-mediated genome instability protein 2; RMI2 is a eukaryotic family of an OB3, oligo-nucleotide-binding proteins. It is an essential component of the RMI complex that plays a vital role in the processing of homologous recombination intermediates in order to limit DNA-crossover-formation in cells.


Pssm-ID: 465022  Cd Length: 128  Bit Score: 183.31  E-value: 1.11e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24308245    21 PPLKVLAEQLR---RDAEGGPGAWRLSRAAAGRGpLDLAAVWMQGRVVMADRGE---ARLRDPSGDFSVRGLERVPRGRP 94
Cdd:pfam16100   1 PALKLFCSQLRtaaDAGSGGAATLRVVRLSIGGG-LLFQRVWLQGTVVEVDNSGddsFLLDDGTGVFTVTGLNELPLGRP 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 24308245    95 CLVPGKYVMVMGVVQACSPEPCLQAVKMTDLSDNPIHESMWELEVEDLH 143
Cdd:pfam16100  80 CLKEGMYVMVVGVIQACSPEPVLRAVKMTDLSDNPDREAMWYLEVEELQ 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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