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Conserved domains on  [gi|19922142|ref|NP_610830|]
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uncharacterized protein Dmel_CG44250, isoform B [Drosophila melanogaster]

Protein Classification

DUF3421 domain-containing protein( domain architecture ID 12112277)

DUF3421 domain-containing protein similar to Ceratitis capitata farnesoic acid O-methyltransferase (FAMeT), which has a measurable role on the fertility of both medfly sexes; also contains a DM9 domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 25-135 5.74e-56

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


:

Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 176.20  E-value: 5.74e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142    25 SDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEHTKTHYEVLVG---QGFAWVPSSSGGVPPNAVRSGTTRTGEPL 101
Cdd:pfam11901   1 SDGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLVAndpSSYEWVPSSDGFVPPGAVSGGRTEDGEPL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922142   102 YVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVRI 135
Cdd:pfam11901  81 YIGRARHDGSLTPGKVHPSHGCCYIPYGGLEVRV 114
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 168-277 2.21e-43

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


:

Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 143.84  E-value: 2.21e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142   168 SDRTPIYAGRAMHEGEMLPAKVVPSKGTAYVCFGGYEFQKPSYEVLTG---YGYVWMNCGH-SIPPNAVTTGRARNGELL 243
Cdd:pfam11901   1 SDGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLVAndpSSYEWVPSSDgFVPPGAVSGGRTEDGEPL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922142   244 YYGRGHYQGSLTPGLISASQRCLYIPYGGREIRI 277
Cdd:pfam11901  81 YIGRARHDGSLTPGKVHPSHGCCYIPYGGLEVRV 114
 
Name Accession Description Interval E-value
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 25-135 5.74e-56

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 176.20  E-value: 5.74e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142    25 SDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEHTKTHYEVLVG---QGFAWVPSSSGGVPPNAVRSGTTRTGEPL 101
Cdd:pfam11901   1 SDGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLVAndpSSYEWVPSSDGFVPPGAVSGGRTEDGEPL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922142   102 YVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVRI 135
Cdd:pfam11901  81 YIGRARHDGSLTPGKVHPSHGCCYIPYGGLEVRV 114
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 168-277 2.21e-43

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 143.84  E-value: 2.21e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142   168 SDRTPIYAGRAMHEGEMLPAKVVPSKGTAYVCFGGYEFQKPSYEVLTG---YGYVWMNCGH-SIPPNAVTTGRARNGELL 243
Cdd:pfam11901   1 SDGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLVAndpSSYEWVPSSDgFVPPGAVSGGRTEDGEPL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922142   244 YYGRGHYQGSLTPGLISASQRCLYIPYGGREIRI 277
Cdd:pfam11901  81 YIGRARHDGSLTPGKVHPSHGCCYIPYGGLEVRV 114
DM9 smart00696
Repeats found in Drosophila proteins;
74-144 2.57e-32

Repeats found in Drosophila proteins;


Pssm-ID: 128937  Cd Length: 71  Bit Score: 113.90  E-value: 2.57e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19922142     74 GFAWVPSSSGGVPPNAVRSGTTRTGEPLYVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVRINTYEVLIKQ 144
Cdd:smart00696   1 GYVWVPSSDGNIPPNAVVGGTDSDGEPLYVGRAYYEGSLLPGKVVPSHGCAYIPYGGQEVRLDSYEVLVGE 71
DM9 smart00696
Repeats found in Drosophila proteins;
146-216 1.04e-28

Repeats found in Drosophila proteins;


Pssm-ID: 128937  Cd Length: 71  Bit Score: 104.65  E-value: 1.04e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19922142    146 HDVWVPASPSYTPPGAVIAGHDSDRTPIYAGRAMHEGEMLPAKVVPSKGTAYVCFGGYEFQKPSYEVLTGY 216
Cdd:smart00696   1 GYVWVPSSDGNIPPNAVVGGTDSDGEPLYVGRAYYEGSLLPGKVVPSHGCAYIPYGGQEVRLDSYEVLVGE 71
 
Name Accession Description Interval E-value
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 25-135 5.74e-56

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 176.20  E-value: 5.74e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142    25 SDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEHTKTHYEVLVG---QGFAWVPSSSGGVPPNAVRSGTTRTGEPL 101
Cdd:pfam11901   1 SDGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLVAndpSSYEWVPSSDGFVPPGAVSGGRTEDGEPL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922142   102 YVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVRI 135
Cdd:pfam11901  81 YIGRARHDGSLTPGKVHPSHGCCYIPYGGLEVRV 114
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 168-277 2.21e-43

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 143.84  E-value: 2.21e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142   168 SDRTPIYAGRAMHEGEMLPAKVVPSKGTAYVCFGGYEFQKPSYEVLTG---YGYVWMNCGH-SIPPNAVTTGRARNGELL 243
Cdd:pfam11901   1 SDGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLVAndpSSYEWVPSSDgFVPPGAVSGGRTEDGEPL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 19922142   244 YYGRGHYQGSLTPGLISASQRCLYIPYGGREIRI 277
Cdd:pfam11901  81 YIGRARHDGSLTPGKVHPSHGCCYIPYGGLEVRV 114
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 98-204 9.48e-34

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 118.80  E-value: 9.48e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19922142    98 GEPLYVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVRINTYEVL-IKQQHD-VWVPASPSYTPPGAVIAGHDSDRTPIYA 175
Cdd:pfam11901   3 GSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLvANDPSSyEWVPSSDGFVPPGAVSGGRTEDGEPLYI 82

                          90       100
                  ....*....|....*....|....*....
gi 19922142   176 GRAMHEGEMLPAKVVPSKGTAYVCFGGYE 204
Cdd:pfam11901  83 GRARHDGSLTPGKVHPSHGCCYIPYGGLE 111
DM9 smart00696
Repeats found in Drosophila proteins;
74-144 2.57e-32

Repeats found in Drosophila proteins;


Pssm-ID: 128937  Cd Length: 71  Bit Score: 113.90  E-value: 2.57e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19922142     74 GFAWVPSSSGGVPPNAVRSGTTRTGEPLYVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVRINTYEVLIKQ 144
Cdd:smart00696   1 GYVWVPSSDGNIPPNAVVGGTDSDGEPLYVGRAYYEGSLLPGKVVPSHGCAYIPYGGQEVRLDSYEVLVGE 71
DM9 smart00696
Repeats found in Drosophila proteins;
146-216 1.04e-28

Repeats found in Drosophila proteins;


Pssm-ID: 128937  Cd Length: 71  Bit Score: 104.65  E-value: 1.04e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19922142    146 HDVWVPASPSYTPPGAVIAGHDSDRTPIYAGRAMHEGEMLPAKVVPSKGTAYVCFGGYEFQKPSYEVLTGY 216
Cdd:smart00696   1 GYVWVPSSDGNIPPNAVVGGTDSDGEPLYVGRAYYEGSLLPGKVVPSHGCAYIPYGGQEVRLDSYEVLVGE 71
DM9 smart00696
Repeats found in Drosophila proteins;
2-73 4.14e-28

Repeats found in Drosophila proteins;


Pssm-ID: 128937  Cd Length: 71  Bit Score: 103.11  E-value: 4.14e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19922142      2 DNTWVHSSPYSpLPPYAVIGGHDSDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEHTKTHYEVLVGQ 73
Cdd:smart00696   1 GYVWVPSSDGN-IPPNAVVGGTDSDGEPLYVGRAYYEGSLLPGKVVPSHGCAYIPYGGQEVRLDSYEVLVGE 71
DM9 smart00696
Repeats found in Drosophila proteins;
217-286 5.20e-27

Repeats found in Drosophila proteins;


Pssm-ID: 128937  Cd Length: 71  Bit Score: 100.03  E-value: 5.20e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19922142    217 GYVWMNCGH-SIPPNAVTTGRARNGELLYYGRGHYQGSLTPGLISASQRCLYIPYGGREIRINSYEILCRQ 286
Cdd:smart00696   1 GYVWVPSSDgNIPPNAVVGGTDSDGEPLYVGRAYYEGSLLPGKVVPSHGCAYIPYGGQEVRLDSYEVLVGE 71
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 5-62 1.12e-12

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 63.34  E-value: 1.12e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 19922142     5 WVHSSpYSPLPPYAVIGGHDSDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEH 62
Cdd:pfam11901  56 WVPSS-DGFVPPGAVSGGRTEDGEPLYIGRARHDGSLTPGKVHPSHGCCYIPYGGLEV 112
DUF3421 pfam11901
Protein of unknown function (DUF3421); This family of proteins are functionally ...
 239-284 1.91e-09

Protein of unknown function (DUF3421); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 119 to 296 amino acids in length.


Pssm-ID: 463390 [Multi-domain]  Cd Length: 114  Bit Score: 54.09  E-value: 1.91e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 19922142   239 NGELLYYGRGHYQGSLTPGLISASQRCLYIPYGGREIRINSYEILC 284
Cdd:pfam11901   2 DGSPIYVGRAKHEGDLLPGKVVPSKGAAYVPYGGKEHSKSDYEVLV 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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