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Conserved domains on  [gi|18254456|ref|NP_543136|]
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radial spoke head 1 homolog isoform 1 [Homo sapiens]

Protein Classification

MORN repeat-containing protein( domain architecture ID 11468649)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
15-176 2.48e-36

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 131.23  E-value: 2.48e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW 94
Cdd:COG4642  98 FGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEF 177

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  95 ANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPVGPGK 173
Cdd:COG4642 178 KNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADgDRYEGEFKNGKRHGQGT 256


                ...
gi 18254456 174 YVF 176
Cdd:COG4642 257 MTY 259
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
15-176 2.48e-36

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 131.23  E-value: 2.48e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW 94
Cdd:COG4642  98 FGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEF 177

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  95 ANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPVGPGK 173
Cdd:COG4642 178 KNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADgDRYEGEFKNGKRHGQGT 256


                ...
gi 18254456 174 YVF 176
Cdd:COG4642 257 MTY 259
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 20-148 1.05e-24

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 104.14  E-value: 1.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456   20 YEGGRNEaGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLR 99
Cdd:PLN03185  34 YEGEWRR-GMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQ 112

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 18254456  100 HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEG 148
Cdd:PLN03185 113 EGPGKYTWANGNVYLGDMKGGKMSGKGTLTWV-SGDSYEGQWLDGMMHG 160
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
88-109 9.78e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.86  E-value: 9.78e-05
                           10        20
                   ....*....|....*....|..
gi 18254456     88 SRYEGEWANDLRHGHGVYYYIN 109
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 90-112 3.67e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.00  E-value: 3.67e-04
                          10        20
                  ....*....|....*....|...
gi 18254456    90 YEGEWANDLRHGHGVYYYINNDT 112
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
15-176 2.48e-36

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 131.23  E-value: 2.48e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW 94
Cdd:COG4642  98 FGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEF 177

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  95 ANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPVGPGK 173
Cdd:COG4642 178 KNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADgDRYEGEFKNGKRHGQGT 256


                ...
gi 18254456 174 YVF 176
Cdd:COG4642 257 MTY 259
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
18-165 1.98e-35

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 128.92  E-value: 1.98e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:COG4642 124 GGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNG 203

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18254456  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLN 165
Cdd:COG4642 204 QRHGQGTYTYADGDRYEGEFKNGKRHGQGTLTYAD-GDRYEGEFKNGKRHGQGTMTYADgSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
16-143 3.85e-35

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 128.15  E-value: 3.85e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  16 DIGEYEGGRnEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWA 95
Cdd:COG4642 146 NGDVYEGEF-KNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYADGDRYEGEFK 224

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 18254456  96 NDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVN 143
Cdd:COG4642 225 NGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA-DGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
18-187 2.95e-26

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 104.65  E-value: 2.95e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:COG4642  78 GGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNG 157

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPVGPGKYVF 176
Cdd:COG4642 158 KPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYA-NGDVYEGEFKNGQRHGQGTYTYADgDRYEGEFKNGKRHGQGTLTY 236

                       170
                ....*....|.
gi 18254456 177 DVGCEQHGEYR 187
Cdd:COG4642 237 ADGDRYEGEFK 247
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 20-148 1.05e-24

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 104.14  E-value: 1.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456   20 YEGGRNEaGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLR 99
Cdd:PLN03185  34 YEGEWRR-GMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQ 112

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 18254456  100 HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEG 148
Cdd:PLN03185 113 EGPGKYTWANGNVYLGDMKGGKMSGKGTLTWV-SGDSYEGQWLDGMMHG 160
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 34-187 1.11e-23

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 101.06  E-value: 1.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456   34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTY 113
Cdd:PLN03185   1 GELVLSNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTY 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18254456  114 TGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEgtaelihlnhryqgkflnknpvGPGKYVFDVGCEQHGEYR 187
Cdd:PLN03185  81 KGRWRLNLKHGLGYQRYP-NGDVFEGSWIQGLQE----------------------GPGKYTWANGNVYLGDMK 131
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 18-180 1.54e-22

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 97.98  E-value: 1.54e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456   18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:PLN03185   8 GDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456   98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPVGPGKYVF 176
Cdd:PLN03185  88 LKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWA-NGNVYLGDMKGGKMSGKGTLTWVSgDSYEGQWLDGMMHGFGVYTW 166


                 ....*
gi 18254456  177 -DVGC 180
Cdd:PLN03185 167 sDGGC 171
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 23-128 1.40e-19

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 89.12  E-value: 1.40e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456   23 GRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGH 102
Cdd:PLN03185  82 GRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGF 161

                         90       100
                 ....*....|....*....|....*.
gi 18254456  103 GVYYYINNDTYTGEWFAHQRHGQGTY 128
Cdd:PLN03185 162 GVYTWSDGGCYVGTWTRGLKDGKGVF 187
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
16-187 2.64e-18

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 82.70  E-value: 2.64e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  16 DIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV------------RNKKHGQGTFI 83
Cdd:COG4642  41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGfgggggggggkkGGGGGGGGVLE 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  84 YPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGK 162
Cdd:COG4642 121 GDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYAD-GDRYEGEFKNGKRHGQGTLTYANgDVYEGE 199

                       170       180
                ....*....|....*....|....*
gi 18254456 163 FLNKNPVGPGKYVFDVGCEQHGEYR 187
Cdd:COG4642 200 FKNGQRHGQGTYTYADGDRYEGEFK 224
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
16-187 2.10e-11

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 63.05  E-value: 2.10e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  16 DIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWA 95
Cdd:COG4642  18 LGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGG 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  96 NDLRH------------GHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGK 162
Cdd:COG4642  98 FGGGGgggggkkgggggGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPN-GDVYEGEFKNGKPHGQGTLTYADgDRYEGE 176

                       170       180
                ....*....|....*....|....*
gi 18254456 163 FLNKNPVGPGKYVFDVGCEQHGEYR 187
Cdd:COG4642 177 FKNGKRHGQGTLTYANGDVYEGEFK 201
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
15-109 7.82e-07

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 48.14  E-value: 7.82e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  15 NDIGEYEGGRNEAGERHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGA-RYIGEYVRNKKHGQGTFIYPDGS-RYE 91
Cdd:COG2849  51 IKKKLGKGLGKYKKGKLGEWKTYYPNGQlKSEGTYKNGKLEGEWKEYYENGKlKSEGNYKNGKLHGEWKEYYENGKlKEE 130

                        90
                ....*....|....*...
gi 18254456  92 GEWANDLRHGHGVYYYIN 109
Cdd:COG2849 131 GNYKNGKKDGVWKYYDEN 148
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
88-109 9.78e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.86  E-value: 9.78e-05
                           10        20
                   ....*....|....*....|..
gi 18254456     88 SRYEGEWANDLRHGHGVYYYIN 109
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
28-149 1.63e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 41.59  E-value: 1.63e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18254456  28 GERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGS-RYEGEWANDLRHGHGVYY 106
Cdd:COG2849  18 LKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGQlKSEGTYKNGKLEGEWKEY 97

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 18254456 107 YIN-NDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGT 149
Cdd:COG2849  98 YENgKLKSEGNYKNGKLHGEWKEYYENGKLKEEGNYKNGKKDGV 141
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 90-112 3.67e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.00  E-value: 3.67e-04
                          10        20
                  ....*....|....*....|...
gi 18254456    90 YEGEWANDLRHGHGVYYYINNDT 112
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 67-89 4.69e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 36.62  E-value: 4.69e-04
                          10        20
                  ....*....|....*....|...
gi 18254456    67 YIGEYVRNKKHGQGTFIYPDGSR 89
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
65-86 6.42e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 36.55  E-value: 6.42e-04
                           10        20
                   ....*....|....*....|..
gi 18254456     65 ARYIGEYVRNKKHGQGTFIYPD 86
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
111-131 1.48e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.39  E-value: 1.48e-03
                           10        20
                   ....*....|....*....|.
gi 18254456    111 DTYTGEWFAHQRHGQGTYLYA 131
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYA 21
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
28-100 2.01e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 38.13  E-value: 2.01e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18254456  28 GERHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGA-RYIGEYVRNKKHGQGTFIYPDGSR-YEGEWANDLRH 100
Cdd:COG2849  88 GKLEGEWKEYYENGKlKSEGNYKNGKLHGEWKEYYENGKlKEEGNYKNGKKDGVWKYYDENGKLvKEEEYKNGKKV 163
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
42-63 4.60e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 33.85  E-value: 4.60e-03
                           10        20
                   ....*....|....*....|..
gi 18254456     42 DTYEGSYEFGKRHGQGIYKFKN 63
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 44-66 8.46e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 33.15  E-value: 8.46e-03
                          10        20
                  ....*....|....*....|...
gi 18254456    44 YEGSYEFGKRHGQGIYKFKNGAR 66
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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