|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
128-648 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 711.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 128 NPTNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLkVNPGLEG---YALPRKCNTEQagrpkcpl 204
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPE-IQSGRETeptVCPPRECQSPT-------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 205 dPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRD-GREKAVV 283
Cdd:smart00350 72 -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVkGLPVFAT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 284 GVRAPYMRVVGITVDSEGAGAIsrYSNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLP 363
Cdd:smart00350 151 YIEANHVRKLDYKRSFEDSSFS--VQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLP 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 364 DGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDE 443
Cdd:smart00350 229 DGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 444 FDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHD 522
Cdd:smart00350 309 FDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVD 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 523 ESRDITLAKHIINVHLSSnKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRsgagQQEKASDKR 602
Cdd:smart00350 389 EERDRELAKHVVDLHRYS-HPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLR----KEDSQTESR 463
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 24645774 603 LSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTL 648
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
331-646 |
0e+00 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 653.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAG 410
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 411 LTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFG 490
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 491 RWDDTKGE-ENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCRTHC 569
Cdd:cd17756 161 RYDDLKTPgDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQENEGEIPISKLKRYIAYCRAKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 570 GPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
28-720 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 591.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 28 QAVKKKYKEFIRTfneenffYKYRDTLKR--NYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEI 105
Cdd:COG1241 3 SDLVDKFEEFLRR-------YKYRDEILElaQEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 106 TAprpeheEHMHDIQILLSSNANPTNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIpnlKVNPGLEG 185
Cdd:COG1241 76 YD------VSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTET---YVPQTGEK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 186 YALPRKCntEQAGRPKcpldPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYS 265
Cdd:COG1241 147 LQEPHEC--PGCGRQG----PFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILR 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 266 IRKvgkpsRRDGREKAvvGVRAPYMRVVGITVDSEGAGAIsrysNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRD 345
Cdd:COG1241 221 IEQ-----RTSGRGKS--TIFDLYLEANSIEVEEKEFEEI----EITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEE 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 346 IKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKD-PQTRNF 424
Cdd:COG1241 290 IKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGRW 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 425 VMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDF 503
Cdd:COG1241 370 TLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPiAEQIDL 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 504 MPTILSRFDMIFIVKDIHDESRDITLAKHIINVH-----LSSNKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAG 578
Cdd:COG1241 450 PPTLLSRFDLIFVLRDKPDEERDRELARHILKVHragelLEQEIEEETEEVKPEIDPDLLRKYIAYARRNVFPVLTEEAK 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 579 EKLKSRYVLMRSgagqqeKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDAAM---TGS 655
Cdd:COG1241 530 DLIEDFYVDMRK------KGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVdpeTGK 603
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 656 L-AGA-EGFTTEEDQETLNRIE---KQLKRRFaiGSQVSEQNILQDFLRQKYEERTVMKVIHTMIRRGEL 720
Cdd:COG1241 604 FdIDViETGTSKSQRDKMKLIKdiiKELEEES--SGGAPIEDVIEEAEEEGIDREKAEELIEKLKRKGEI 671
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
30-720 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 576.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 30 VKKKYKEFIRTFNEENFFYKYRDTLKRNYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEITAPR 109
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 110 PEHEEHMHdIQILLSSNANPtnIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLKV-NPGLEGYAL 188
Cdd:NF040949 81 AEEVAKFH-VRFRNLPRTVP--LRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEeEESYEIVEP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 189 PRKCnteqagrPKCP-LDPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIR 267
Cdd:NF040949 158 PTVC-------PVCGkPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 268 KVGKPsRRDGRekavvGVRAPYMRVVGITVDSEgagaISRYSNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIK 347
Cdd:NF040949 231 PDSSL-KKGSR-----PIFKNYIEANHIEVSQK----ELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIK 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 348 KAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVME 427
Cdd:NF040949 301 EAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLE 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 428 GGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPT 506
Cdd:NF040949 381 AGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSvAENIDLPPT 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 507 ILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPsepaegEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYV 586
Cdd:NF040949 461 ILSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEKVKP------EIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYV 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 587 LMRSGAGQQEKASDkrlSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQ---------VST----LDAAMT 653
Cdd:NF040949 535 EMRKSSKSSEDPDS---PIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLaflesvgidVETgkidIDTIMT 611
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 654 GslagaegfTTEEDQETLNRIEKQLKRRFAIGSQVSEQNILQDFLRQKYEERTVMKVIHTMIRRGEL 720
Cdd:NF040949 612 G--------KPKSKREKMSKIVEIIKELEEEEECVKIKELIKEAEKKGIDEEKVEELISDLKRSGEI 670
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
315-537 |
4.31e-145 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 423.09 E-value: 4.31e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 315 EEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKV 394
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 395 APIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTT 474
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24645774 475 LNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVH 537
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSiAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
132-719 |
7.81e-89 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 298.45 E-value: 7.81e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 132 IRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVipnlkvnpGLEGYalpRKCNTEQ-----AGRPKCPL-- 204
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKI--------GLNDY---QPCTCEHyeyviQGEVNEPLlc 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 205 ------DPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIP--------------------RHLQLFCDRSLCERVVPGNRV 258
Cdd:PTZ00111 287 necnskYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRV 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 259 LIQGIYSIrkvgKPSRRDGREKAVVGVRAPYMRVVGITV--------DSEGAGAISRYSNITSDEEEHFRRMAASGDIYE 330
Cdd:PTZ00111 367 TVVGILKV----TPIRTSTTRRTLKSLYTYFVNVIHVKVinstnanqPEKGLKYLGNENDFSDLQVYKILELSRNPMIYR 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSR-----KRLPDGLCR----RGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYT 401
Cdd:PTZ00111 443 ILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYT 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 402 SGKGSSAAGLTASV-MKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 480
Cdd:PTZ00111 523 SGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETA 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 481 VLAAANSIFGRWDDTKGE-ENIDFMPTILSRFDMIFIVKDIHDESRD----ITLAKHIINVHL--SSNKSAP-------- 545
Cdd:PTZ00111 603 ILASCNPINSRYNKNKAViENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMtgSGNDEDTydrsntmh 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 546 -------SEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQ----------QEKASDKRL----- 603
Cdd:PTZ00111 683 vedeslrSEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQtsnldelehaQEDDDDDLYyqssg 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 604 --SIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDaAMTGSLAGA-------EGFTTEEDQEtLNRI 674
Cdd:PTZ00111 763 trMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQ-SLVDPTTGKidfdqlhQGITTNKMQQ-LNQM 840
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 675 EKQLKRRFAIGS-QVSEQNI-LQDFLRQKYEE-------------RTVMKVIHTMIRRGE 719
Cdd:PTZ00111 841 YEQVLSVLTRSSnQDSNKSLdLNEVLSLCHKTfkdnrdhkdgeiyKLISEVLNKMVQEGT 900
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
31-125 |
8.76e-23 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 93.13 E-value: 8.76e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 31 KKKYKEFIRTF-NEENFFYKYRDTLKRNYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEItAPR 109
Cdd:pfam14551 1 KRKFKDFLEEFrEDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKEL-SED 79
|
90
....*....|....*.
gi 24645774 110 PEHEEHMHDIQILLSS 125
Cdd:pfam14551 80 PDYAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
128-648 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 711.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 128 NPTNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLkVNPGLEG---YALPRKCNTEQagrpkcpl 204
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPE-IQSGRETeptVCPPRECQSPT-------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 205 dPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRD-GREKAVV 283
Cdd:smart00350 72 -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVkGLPVFAT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 284 GVRAPYMRVVGITVDSEGAGAIsrYSNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLP 363
Cdd:smart00350 151 YIEANHVRKLDYKRSFEDSSFS--VQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLP 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 364 DGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDE 443
Cdd:smart00350 229 DGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 444 FDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHD 522
Cdd:smart00350 309 FDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVD 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 523 ESRDITLAKHIINVHLSSnKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRsgagQQEKASDKR 602
Cdd:smart00350 389 EERDRELAKHVVDLHRYS-HPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLR----KEDSQTESR 463
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 24645774 603 LSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTL 648
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
331-646 |
0e+00 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 653.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAG 410
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 411 LTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFG 490
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 491 RWDDTKGE-ENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCRTHC 569
Cdd:cd17756 161 RYDDLKTPgDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQENEGEIPISKLKRYIAYCRAKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 570 GPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
28-720 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 591.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 28 QAVKKKYKEFIRTfneenffYKYRDTLKR--NYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEI 105
Cdd:COG1241 3 SDLVDKFEEFLRR-------YKYRDEILElaQEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 106 TAprpeheEHMHDIQILLSSNANPTNIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIpnlKVNPGLEG 185
Cdd:COG1241 76 YD------VSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTET---YVPQTGEK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 186 YALPRKCntEQAGRPKcpldPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYS 265
Cdd:COG1241 147 LQEPHEC--PGCGRQG----PFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILR 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 266 IRKvgkpsRRDGREKAvvGVRAPYMRVVGITVDSEGAGAIsrysNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRD 345
Cdd:COG1241 221 IEQ-----RTSGRGKS--TIFDLYLEANSIEVEEKEFEEI----EITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEE 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 346 IKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKD-PQTRNF 424
Cdd:COG1241 290 IKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGRW 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 425 VMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDF 503
Cdd:COG1241 370 TLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPiAEQIDL 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 504 MPTILSRFDMIFIVKDIHDESRDITLAKHIINVH-----LSSNKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAG 578
Cdd:COG1241 450 PPTLLSRFDLIFVLRDKPDEERDRELARHILKVHragelLEQEIEEETEEVKPEIDPDLLRKYIAYARRNVFPVLTEEAK 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 579 EKLKSRYVLMRSgagqqeKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDAAM---TGS 655
Cdd:COG1241 530 DLIEDFYVDMRK------KGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVdpeTGK 603
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 656 L-AGA-EGFTTEEDQETLNRIE---KQLKRRFaiGSQVSEQNILQDFLRQKYEERTVMKVIHTMIRRGEL 720
Cdd:COG1241 604 FdIDViETGTSKSQRDKMKLIKdiiKELEEES--SGGAPIEDVIEEAEEEGIDREKAEELIEKLKRKGEI 671
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
30-720 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 576.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 30 VKKKYKEFIRTFNEENFFYKYRDTLKRNYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEITAPR 109
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 110 PEHEEHMHdIQILLSSNANPtnIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLKV-NPGLEGYAL 188
Cdd:NF040949 81 AEEVAKFH-VRFRNLPRTVP--LRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEeEESYEIVEP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 189 PRKCnteqagrPKCP-LDPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSIR 267
Cdd:NF040949 158 PTVC-------PVCGkPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 268 KVGKPsRRDGRekavvGVRAPYMRVVGITVDSEgagaISRYSNITSDEEEHFRRMAASGDIYERLSQSLAPSIFGSRDIK 347
Cdd:NF040949 231 PDSSL-KKGSR-----PIFKNYIEANHIEVSQK----ELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIK 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 348 KAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVME 427
Cdd:NF040949 301 EAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLE 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 428 GGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPT 506
Cdd:NF040949 381 AGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSvAENIDLPPT 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 507 ILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPsepaegEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYV 586
Cdd:NF040949 461 ILSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEKVKP------EIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYV 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 587 LMRSGAGQQEKASDkrlSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQ---------VST----LDAAMT 653
Cdd:NF040949 535 EMRKSSKSSEDPDS---PIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLaflesvgidVETgkidIDTIMT 611
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 654 GslagaegfTTEEDQETLNRIEKQLKRRFAIGSQVSEQNILQDFLRQKYEERTVMKVIHTMIRRGEL 720
Cdd:NF040949 612 G--------KPKSKREKMSKIVEIIKELEEEEECVKIKELIKEAEKKGIDEEKVEELISDLKRSGEI 670
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
331-646 |
1.50e-145 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 427.53 E-value: 1.50e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAG 410
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 411 LTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFG 490
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 491 RWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEG--EISLSTFKKYIHYCRt 567
Cdd:cd17706 161 RYNPKLSpIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQVKPEEDgiPIDIELLRKYILYAR- 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24645774 568 HCGPRLSEAAGEKLKSRYVLMRsgagqqeKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17706 240 QIHPKISEEAREKLVRWYVELR-------KESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
315-537 |
4.31e-145 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 423.09 E-value: 4.31e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 315 EEEHFRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKV 394
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 395 APIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTT 474
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24645774 475 LNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVH 537
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSiAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
330-644 |
2.02e-129 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 386.42 E-value: 2.02e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 330 ERLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAA 409
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 410 GLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIF 489
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 490 GRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHlsSNKSApsEPAEGEISLSTFKKYIHYCRTH 568
Cdd:cd17761 161 GRFDSYRPvAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTH--SGGEM--REIKPEIDPDLLRKYIAYARKN 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24645774 569 CGPRLSEAAGEKLKSRYVLMRSgagqqeKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQ 644
Cdd:cd17761 237 VRPVLTEEAKQLIKDFYVEMRK------SGQETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
331-642 |
9.21e-126 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 377.56 E-value: 9.21e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRlPDGLCR-RGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAA 409
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKN-PGGKHRiRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 410 GLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIF 489
Cdd:cd17753 80 GLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 490 GRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSA---------------PSEPAEGEI 553
Cdd:cd17753 160 GRYNPTLTfAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENdedregeeeknqrqrPKETKVEPI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 554 SLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRsgagqqeKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATD 633
Cdd:cd17753 240 PQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLR-------KESMATGSLPITVRHLESIIRISEAHAKMHLREYVSE 312
|
....*....
gi 24645774 634 EHVNEALRL 642
Cdd:cd17753 313 EDVDMAIRV 321
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
331-646 |
9.65e-126 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 376.71 E-value: 9.65e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAG 410
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 411 LTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFG 490
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 491 RWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSapsepAEGEISLSTFKKYIHYCRTHC 569
Cdd:cd17757 161 RYDRSKSlKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEA-----IEPPFTAEQLKRYIAYARTFK 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 570 gPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRlsipITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17757 236 -PKLTKEAKDELVEQYKELRQDDASGSTRSSYR----ITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
331-646 |
2.66e-125 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 375.62 E-value: 2.66e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCR-RGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAA 409
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKTGGKyRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 410 GLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIF 489
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 490 GRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSsnkSAPSEPAEGEISLSTFKKYIHYCRTH 568
Cdd:cd17755 161 SRYNPKLTvVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLE---DTPEHIQDEVLDVEVLTDYISYAREH 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24645774 569 CGPRLSEAAGEKLKSRYVLMRSGagqqekASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17755 238 IHPKLSEEAAQELVQAYVDMRKM------GSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
331-646 |
1.40e-121 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 365.96 E-value: 1.40e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRlPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAG 410
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 411 LTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFG 490
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 491 RWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLsSNKSAPSEPAegEISLSTFKKYIHYCRTHc 569
Cdd:cd17758 160 RYNPRRSpEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQ-HNKQPDSDFE--PLDPKLLRAYIALAKRK- 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 570 GPRLSEAAGEKLKSRYVLMRsgagqQEKASDKRLSIpITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17758 236 RPTVPPALADYIVQAYVEMR-----QEAKRSKDFTF-TTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
332-644 |
2.86e-109 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 334.05 E-value: 2.86e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 332 LSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGL 411
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 412 TASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGR 491
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 492 WDDTKGE-ENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNksapsepaegeislsTFKKYIHYCRTHCG 570
Cdd:cd17754 162 YDVYKTPmENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRYIK---------------FLRKYIHYAKERIK 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24645774 571 PRLSEAAGEKLKSRYVLMRSgagQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQ 644
Cdd:cd17754 227 PKLTQEAAEYIAEEYADLRN---DDNTKTDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
132-719 |
7.81e-89 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 298.45 E-value: 7.81e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 132 IRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVipnlkvnpGLEGYalpRKCNTEQ-----AGRPKCPL-- 204
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKI--------GLNDY---QPCTCEHyeyviQGEVNEPLlc 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 205 ------DPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIP--------------------RHLQLFCDRSLCERVVPGNRV 258
Cdd:PTZ00111 287 necnskYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRV 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 259 LIQGIYSIrkvgKPSRRDGREKAVVGVRAPYMRVVGITV--------DSEGAGAISRYSNITSDEEEHFRRMAASGDIYE 330
Cdd:PTZ00111 367 TVVGILKV----TPIRTSTTRRTLKSLYTYFVNVIHVKVinstnanqPEKGLKYLGNENDFSDLQVYKILELSRNPMIYR 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSR-----KRLPDGLCR----RGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYT 401
Cdd:PTZ00111 443 ILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYT 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 402 SGKGSSAAGLTASV-MKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 480
Cdd:PTZ00111 523 SGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETA 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 481 VLAAANSIFGRWDDTKGE-ENIDFMPTILSRFDMIFIVKDIHDESRD----ITLAKHIINVHL--SSNKSAP-------- 545
Cdd:PTZ00111 603 ILASCNPINSRYNKNKAViENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMtgSGNDEDTydrsntmh 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 546 -------SEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQ----------QEKASDKRL----- 603
Cdd:PTZ00111 683 vedeslrSEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQtsnldelehaQEDDDDDLYyqssg 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 604 --SIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDaAMTGSLAGA-------EGFTTEEDQEtLNRI 674
Cdd:PTZ00111 763 trMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQ-SLVDPTTGKidfdqlhQGITTNKMQQ-LNQM 840
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 675 EKQLKRRFAIGS-QVSEQNI-LQDFLRQKYEE-------------RTVMKVIHTMIRRGE 719
Cdd:PTZ00111 841 YEQVLSVLTRSSnQDSNKSLdLNEVLSLCHKTfkdnrdhkdgeiyKLISEVLNKMVQEGT 900
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
331-646 |
7.35e-77 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 248.99 E-value: 7.35e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 331 RLSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDG--LCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSA 408
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 409 AGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMrEDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSI 488
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKM-GSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 489 FGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVhlssnksapsepaegeislstfKKYIHYCRT 567
Cdd:cd17759 160 GGHYNKGKTvSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEHHQLL----------------------RKYISYARQ 217
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24645774 568 HCGPRLSEAAGEKLKSRYVLMRsgagqqeKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17759 218 YVNPVLSKDASEALQEFYLELR-------KQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
335-646 |
2.01e-68 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 227.04 E-value: 2.01e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 335 SLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTAS 414
Cdd:cd17760 5 SLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGLTVT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 415 VMKDpqTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIfGRWDD 494
Cdd:cd17760 85 AVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQYDP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 495 TKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIInvhlsSNKSAPSEpAEGEISLSTFKKYIHYCRTHcGPRL 573
Cdd:cd17760 162 NESiSVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL-----ENKGEPSK-SSKLWSMEKMRTYFCLIKNL-RPVL 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24645774 574 SEAAGEKLKSRYvlmrsgagQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVS 646
Cdd:cd17760 235 SDEANAILLRYY--------QLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
131-266 |
1.42e-44 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 155.72 E-value: 1.42e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 131 NIRQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPnLKVNPglegyalPRKCNteqagRPKCP-LDPFFI 209
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVG-VKITE-------PTKCP-----NPECGnKDPFKL 67
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 24645774 210 MPDKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQGIYSI 266
Cdd:pfam17207 68 VHEKSKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRV 124
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
556-647 |
2.76e-34 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 125.35 E-value: 2.76e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 556 STFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAgqqekaSDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEH 635
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKES------TGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEED 74
|
90
....*....|..
gi 24645774 636 VNEALRLFQVST 647
Cdd:pfam17855 75 VEEAIRLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
31-125 |
8.76e-23 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 93.13 E-value: 8.76e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 31 KKKYKEFIRTF-NEENFFYKYRDTLKRNYLNGRYFLEIEMEDLVGFDETLADKLNKQPTEHLEIFEEAAREVADEItAPR 109
Cdd:pfam14551 1 KRKFKDFLEEFrEDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKEL-SED 79
|
90
....*....|....*.
gi 24645774 110 PEHEEHMHDIQILLSS 125
Cdd:pfam14551 80 PDYAEEEKEFQVRFYN 95
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
366-517 |
2.90e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 41.75 E-value: 2.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645774 366 LCRRGDINVLLLGDPGTAKSQLLKFV------EKVAPIAVYTSGKGSSAAGLtasvmKDPQTRNFVMEGGAMVLADGGVV 439
Cdd:cd00009 14 LELPPPKNLLLYGPPGTGKTTLARAIanelfrPGAPFLYLNASDLLEGLVVA-----ELFGHFLVRLLFELAEKAKPGVL 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24645774 440 CIDEFDKMREDDRVAIHEAMEQQTisiakagITTTLNSRCSVLAAANSIfgrwddtkgeENIDFMPTILSRFDMIFIV 517
Cdd:cd00009 89 FIDEIDSLSRGAQNALLRVLETLN-------DLRIDRENVRVIGATNRP----------LLGDLDRALYDRLDIRIVI 149
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
373-446 |
5.88e-04 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 40.74 E-value: 5.88e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24645774 373 NVLLLGDPGTAKSQLLKFVEKV---APIAVYTSGKGSSAAGLTASVmkDPQTRNFVMEGGAMVLA--DGGVVCIDEFDK 446
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAAlsnRPVFYVQLTRDTTEEDLFGRR--NIDPGGASWVDGPLVRAarEGEIAVLDEINR 77
|
|
| |
