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Conserved domains on  [gi|255767797|ref|NP_391669|]
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putative dTDP glycosyl/glycerophosphate transferase or transport [Bacillus subtilis subsp. subtilis str. 168]

Protein Classification

CDP-glycerol glycerophosphotransferase family protein( domain architecture ID 10004838)

CDP-glycerol glycerophosphotransferase family protein similar to Bacillus subtilis spore coat polysaccharide biosynthesis protein SpsB and CDP-glycerol poly(glycerophosphate) glycerophosphotransferase, which is responsible for the polymerization of the main chain of the major teichoic acid

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyphos_transf super family cl42225
CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Wall-associated teichoic acids ...
 178-448 8.32e-15

CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.


The actual alignment was detected with superfamily member COG1887:

Pssm-ID: 478041  Cd Length: 369  Bit Score: 75.80  E-value: 8.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 178 FIEAIDTVDALFEQEKISAVIVGTAEDIY----SRVL---------ALMCQRKGAVSICLQHGA---LMGDEAFIPVFTT 241
Cdd:COG1887   54 VVWVVDDDSKRLPKEGVKVVKRGSLKYLYalarAKYLvsnhyfpfpSYFRKRKGQKYVQLWHGTplkKIGLDDPPRYLKR 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 242 YQAVFGAY--------EAEWFIRK--GCKPEQILVTGHPRFDQIFNRTPM-DMSIFYRKLAFQPTKKIVLIAtqP-FSED 309
Cdd:COG1887  134 VLREYRNWdyllssseESTEIFRRafGYPEGEVLETGYPRNDVLFDADREeLREELRERLGIPEDKKVILYA--PtWRDD 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 310 FYSGVLQGLSDQKQL--------QIIIKPHPWEIGKNKLDLYHEAakkhqacRVIKKELELYDLLPYVDAAVTQTSTVGL 381
Cdd:COG1887  212 EDNFDDYLDLDLERLaellgddyVLLVRLHPFVKDSLDEKYSDRI-------IDVSDYPDINDLLLASDVLITDYSSVMF 284

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255767797 382 EAMLFQKPVLIgkssgnrsYPY----YESLGDFMFDQPDEL----AHT---LVEVLRSPD-VHQKAEEARLAFIAANYP 448
Cdd:COG1887  285 DFALLDRPIIF--------YAYdleeYRDERGFYFDYEEDApgpvVTTfeeLIDAIEDILeNGDEYAEKYKAFRERFFP 355
 
Name Accession Description Interval E-value
TagB COG1887
CDP-glycerol glycerophosphotransferase, TagB/SpsB family [Cell wall/membrane/envelope ...
 178-448 8.32e-15

CDP-glycerol glycerophosphotransferase, TagB/SpsB family [Cell wall/membrane/envelope biogenesis, Lipid transport and metabolism];


Pssm-ID: 441491  Cd Length: 369  Bit Score: 75.80  E-value: 8.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 178 FIEAIDTVDALFEQEKISAVIVGTAEDIY----SRVL---------ALMCQRKGAVSICLQHGA---LMGDEAFIPVFTT 241
Cdd:COG1887   54 VVWVVDDDSKRLPKEGVKVVKRGSLKYLYalarAKYLvsnhyfpfpSYFRKRKGQKYVQLWHGTplkKIGLDDPPRYLKR 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 242 YQAVFGAY--------EAEWFIRK--GCKPEQILVTGHPRFDQIFNRTPM-DMSIFYRKLAFQPTKKIVLIAtqP-FSED 309
Cdd:COG1887  134 VLREYRNWdyllssseESTEIFRRafGYPEGEVLETGYPRNDVLFDADREeLREELRERLGIPEDKKVILYA--PtWRDD 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 310 FYSGVLQGLSDQKQL--------QIIIKPHPWEIGKNKLDLYHEAakkhqacRVIKKELELYDLLPYVDAAVTQTSTVGL 381
Cdd:COG1887  212 EDNFDDYLDLDLERLaellgddyVLLVRLHPFVKDSLDEKYSDRI-------IDVSDYPDINDLLLASDVLITDYSSVMF 284

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255767797 382 EAMLFQKPVLIgkssgnrsYPY----YESLGDFMFDQPDEL----AHT---LVEVLRSPD-VHQKAEEARLAFIAANYP 448
Cdd:COG1887  285 DFALLDRPIIF--------YAYdleeYRDERGFYFDYEEDApgpvVTTfeeLIDAIEDILeNGDEYAEKYKAFRERFFP 355
Glyphos_transf pfam04464
CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Wall-associated teichoic acids ...
 258-442 1.45e-09

CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.


Pssm-ID: 398259  Cd Length: 360  Bit Score: 59.67  E-value: 1.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797  258 GCKPEQILVTGHPRFDQIFNRTPMDMSIFYRKLAFQPTKKIVLIA-----TQPFSEDFYSgvLQGLSDQKQLQ------- 325
Cdd:pfam04464 145 NIDKERILETGYPRNDVLFNANNEDVQRIRERLGIPLGKKVILYAptwrdDERGSIGSYR--FELLIDLERLAfalgndy 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797  326 -IIIKPHPWEigKNKLDLYHeaakKHQACRVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPVLI-----GKSSGNR 399
Cdd:pfam04464 223 vILLKMHPLI--QNNIDIFE----SSGYVVDVSDYEDVEDLLLASDILITDYSSVMFDYAVLDRPIIFyaydlETYSATR 296

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 255767797  400 SYpYYeslgDFMFDQPDELAHT---LVEVLRSPDVH-QKAEEARLAF 442
Cdd:pfam04464 297 GF-YL----DYESEAPGPVVETfdeLIDALKSGDWDdDYYARKRRAF 338
beta_Kdo_transferase_KpsS_like cd16438
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsS like; KpsS is a ...
 308-391 1.36e-06

beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsS like; KpsS is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. It is part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria.


Pssm-ID: 319746  Cd Length: 254  Bit Score: 49.52  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 308 EDFYSgVLQGLSDQ--KQLQIIIKPHPWEIGKNKldlYHEAAKKHQacRVI-KKELELYDLLPYVDAAVTQTSTVGLEAM 384
Cdd:cd16438  117 EQLYE-VLVEAADRlnPDLKIVFKEHPSDPKSYD---YKELYKKHP--RVIfANGNDTQELIEGAEAVITINSTVGIEAL 190


                 ....*..
gi 255767797 385 LFQKPVL 391
Cdd:cd16438  191 LLGKPVI 197
PRK13609 PRK13609
diacylglycerol glucosyltransferase; Provisional
 258-438 9.01e-04

diacylglycerol glucosyltransferase; Provisional


Pssm-ID: 237445 [Multi-domain]  Cd Length: 380  Bit Score: 41.63  E-value: 9.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 258 GCKPEQILVTGHPRFDQIfnRTPMDMSIFYRKLAFQPTKKIVLIATQPFsedfysGVLQG-------LSDQKQLQIIIKp 330
Cdd:PRK13609 166 GVPPEQVVETGIPIRSSF--ELKINPDIIYNKYQLCPNKKILLIMAGAH------GVLGNvkelcqsLMSVPDLQVVVV- 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 331 hpweIGKN---KLDLYHEAAKKHQACRVIKKELELYDLLPYVDAAVTQTSTVGL-EAMLFQKPVLI-----GKSSGNRSy 401
Cdd:PRK13609 237 ----CGKNealKQSLEDLQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLsEAAALGVPVILykpvpGQEKENAM- 311

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 255767797 402 pYYESLGDFM-FDQPDELAHTLVEVLRSPDVHQKAEEA 438
Cdd:PRK13609 312 -YFERKGAAVvIRDDEEVFAKTEALLQDDMKLLQMKEA 348
 
Name Accession Description Interval E-value
TagB COG1887
CDP-glycerol glycerophosphotransferase, TagB/SpsB family [Cell wall/membrane/envelope ...
 178-448 8.32e-15

CDP-glycerol glycerophosphotransferase, TagB/SpsB family [Cell wall/membrane/envelope biogenesis, Lipid transport and metabolism];


Pssm-ID: 441491  Cd Length: 369  Bit Score: 75.80  E-value: 8.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 178 FIEAIDTVDALFEQEKISAVIVGTAEDIY----SRVL---------ALMCQRKGAVSICLQHGA---LMGDEAFIPVFTT 241
Cdd:COG1887   54 VVWVVDDDSKRLPKEGVKVVKRGSLKYLYalarAKYLvsnhyfpfpSYFRKRKGQKYVQLWHGTplkKIGLDDPPRYLKR 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 242 YQAVFGAY--------EAEWFIRK--GCKPEQILVTGHPRFDQIFNRTPM-DMSIFYRKLAFQPTKKIVLIAtqP-FSED 309
Cdd:COG1887  134 VLREYRNWdyllssseESTEIFRRafGYPEGEVLETGYPRNDVLFDADREeLREELRERLGIPEDKKVILYA--PtWRDD 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 310 FYSGVLQGLSDQKQL--------QIIIKPHPWEIGKNKLDLYHEAakkhqacRVIKKELELYDLLPYVDAAVTQTSTVGL 381
Cdd:COG1887  212 EDNFDDYLDLDLERLaellgddyVLLVRLHPFVKDSLDEKYSDRI-------IDVSDYPDINDLLLASDVLITDYSSVMF 284

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255767797 382 EAMLFQKPVLIgkssgnrsYPY----YESLGDFMFDQPDEL----AHT---LVEVLRSPD-VHQKAEEARLAFIAANYP 448
Cdd:COG1887  285 DFALLDRPIIF--------YAYdleeYRDERGFYFDYEEDApgpvVTTfeeLIDAIEDILeNGDEYAEKYKAFRERFFP 355
Glyphos_transf pfam04464
CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Wall-associated teichoic acids ...
 258-442 1.45e-09

CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.


Pssm-ID: 398259  Cd Length: 360  Bit Score: 59.67  E-value: 1.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797  258 GCKPEQILVTGHPRFDQIFNRTPMDMSIFYRKLAFQPTKKIVLIA-----TQPFSEDFYSgvLQGLSDQKQLQ------- 325
Cdd:pfam04464 145 NIDKERILETGYPRNDVLFNANNEDVQRIRERLGIPLGKKVILYAptwrdDERGSIGSYR--FELLIDLERLAfalgndy 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797  326 -IIIKPHPWEigKNKLDLYHeaakKHQACRVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPVLI-----GKSSGNR 399
Cdd:pfam04464 223 vILLKMHPLI--QNNIDIFE----SSGYVVDVSDYEDVEDLLLASDILITDYSSVMFDYAVLDRPIIFyaydlETYSATR 296

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 255767797  400 SYpYYeslgDFMFDQPDELAHT---LVEVLRSPDVH-QKAEEARLAF 442
Cdd:pfam04464 297 GF-YL----DYESEAPGPVVETfdeLIDALKSGDWDdDYYARKRRAF 338
beta_Kdo_transferase_KpsS_like cd16438
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsS like; KpsS is a ...
 308-391 1.36e-06

beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsS like; KpsS is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. It is part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria.


Pssm-ID: 319746  Cd Length: 254  Bit Score: 49.52  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 308 EDFYSgVLQGLSDQ--KQLQIIIKPHPWEIGKNKldlYHEAAKKHQacRVI-KKELELYDLLPYVDAAVTQTSTVGLEAM 384
Cdd:cd16438  117 EQLYE-VLVEAADRlnPDLKIVFKEHPSDPKSYD---YKELYKKHP--RVIfANGNDTQELIEGAEAVITINSTVGIEAL 190


                 ....*..
gi 255767797 385 LFQKPVL 391
Cdd:cd16438  191 LLGKPVI 197
beta_Kdo_transferase_KpsC cd16437
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC; KpsC is a ...
 296-390 4.83e-05

beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC; KpsC is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. It is part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides, that are important virulence factors for many pathogenic bacteria. KpsC contains a domain duplication.


Pssm-ID: 319745  Cd Length: 256  Bit Score: 44.80  E-value: 4.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 296 KKIVLIATQPFSE----------DFYSGVLQG-LSDQKQLQIIIKPHPWEIGKNKLDlYHEAAKKHQACRVIKKELELYD 364
Cdd:cd16437  109 RDIILVPGQVENDasittgnasiHSNAALLRAvREENPDAEIWYKVHPDVLEGKRTG-YFLALRATQLVDLIAEDVDIQS 187

                         90       100
                 ....*....|....*....|....*.
gi 255767797 365 LLPYVDAAVTQTSTVGLEAMLFQKPV 390
Cdd:cd16437  188 LLRRVDRVHTMTSLYGFEALLAGKQV 213
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 251-434 1.28e-04

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 44.23  E-value: 1.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 251 AEWFIRKGCKPEQILVTG---HPRFDQIFNRTPMdmsifYRKLAFQPTKKIVLI-ATQPFSEDFYSGVlQGLSDQkqlqi 326
Cdd:cd17507  154 KRELVERGVTPSQIKVTGipvRPSFAEVRDKDEA-----RNELNLSPDKPTVLLmGGGGGMGPVKETV-EALLDS----- 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 327 iikPHPWEI----GKNKlDLYHE---AAKKHQACRVIKKELELYDLLPYVDAAVT----QTSTvglEAMLFQKPVLI--- 392
Cdd:cd17507  223 ---LRAGQVlvvcGKNK-KLYEKlsgLEEDYINVRVLGYVDDMNELMAASDLVITkpggLTIS---EALARGLPVIIydp 295

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 255767797 393 --GKSSGNrsYPYYESLGDFMFDQPDELAHTLVEVLRSPDVHQK 434
Cdd:cd17507  296 ipGQEEEN--ADFLENNGAGIIARDPEELLEIVARLIDPPSLLR 337
beta_Kdo_transferase_KpsC_1 cd16440
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC, repeat1; KpsC is a ...
 290-390 4.46e-04

beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC, repeat1; KpsC is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. It is part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria. KpsC contains a domain duplication.


Pssm-ID: 319748  Cd Length: 262  Bit Score: 42.09  E-value: 4.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 290 LAFQPTKKIVLIATQPF-----------SEDFYSGVLQGLSDQKQLQIIIKPHPWEIGKNKLDLYHEAAKKHQaCRVIKK 358
Cdd:cd16440  106 LLGPPPRPRVLVVDQTAgdasiayggasAASFRRMLEAALEENPDAEILVKTHPDVLAGKKKGYLLELAADPR-VTLLAE 184

                         90       100       110
                 ....*....|....*....|....*....|..
gi 255767797 359 ELELYDLLPYVDAAVTQTSTVGLEAMLFQKPV 390
Cdd:cd16440  185 DVNPISLLEHADAVYTVTSQMGFEALLAGKPV 216
PRK13609 PRK13609
diacylglycerol glucosyltransferase; Provisional
 258-438 9.01e-04

diacylglycerol glucosyltransferase; Provisional


Pssm-ID: 237445 [Multi-domain]  Cd Length: 380  Bit Score: 41.63  E-value: 9.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 258 GCKPEQILVTGHPRFDQIfnRTPMDMSIFYRKLAFQPTKKIVLIATQPFsedfysGVLQG-------LSDQKQLQIIIKp 330
Cdd:PRK13609 166 GVPPEQVVETGIPIRSSF--ELKINPDIIYNKYQLCPNKKILLIMAGAH------GVLGNvkelcqsLMSVPDLQVVVV- 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 331 hpweIGKN---KLDLYHEAAKKHQACRVIKKELELYDLLPYVDAAVTQTSTVGL-EAMLFQKPVLI-----GKSSGNRSy 401
Cdd:PRK13609 237 ----CGKNealKQSLEDLQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLsEAAALGVPVILykpvpGQEKENAM- 311

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 255767797 402 pYYESLGDFM-FDQPDELAHTLVEVLRSPDVHQKAEEA 438
Cdd:PRK13609 312 -YFERKGAAVvIRDDEEVFAKTEALLQDDMKLLQMKEA 348
beta_Kdo_transferase cd16436
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase; KpsC and KpsS are retaining ...
 288-408 1.38e-03

beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase; KpsC and KpsS are retaining beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferases. They are part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria.


Pssm-ID: 319744  Cd Length: 222  Bit Score: 40.22  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 288 RKLAFQPTKKIVLIATQPFSEdfySGVLQGLSDQKQLQ--------------IIIKPHPWEIGKNKLDLYHEAAKKHQAC 353
Cdd:cd16436   62 SRLEMLLKDKAFLVPLQVSGD---VQVRLGGAVASSFLhvlasflehnpdtpIIIKHHPDVRGGKDYGYLIDETLSLERR 138

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 255767797 354 RVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPVligKSSGNrsyPYYESLG 408
Cdd:cd16436  139 VLLVHDVSLPSLLKRAGGVVTVNSTSGFEALLHGKPV---KVLGL---PWYAGWG 187
beta_Kdo_transferase_KpsC_2 cd16439
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC, repeat 2; KpsC is a ...
 325-390 1.46e-03

beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC, repeat 2; KpsC is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. It is part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria. KpsC contains a domain duplication.


Pssm-ID: 319747  Cd Length: 259  Bit Score: 40.50  E-value: 1.46e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 255767797 325 QIIIKPHP-WEIGKNKLDLYHEAAKKHqaCRVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPV 390
Cdd:cd16439  152 FIIYKPHPdVLAGLRKGAVPEAEALKL--ADEVVTDASIADLLEQVDEVHTMTSLTGFEALLRGKKV 216
KpsC COG3563
Capsule polysaccharide export protein KpsC/LpsZ [Cell wall/membrane/envelope biogenesis];
325-390 2.50e-03

Capsule polysaccharide export protein KpsC/LpsZ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442784 [Multi-domain]  Cd Length: 675  Bit Score: 40.23  E-value: 2.50e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 255767797 325 QIIIKPHPwEIGKNKLDLYHEAAKKHQACRVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPV 390
Cdd:COG3563  189 RILVKTHP-DVLAGKKQGYLTAADADDRVRLLTEDVSPWSLLEGADAVYTVTSQMGFEALLAGKPV 253
Capsule_synth pfam05159
Capsule polysaccharide biosynthesis protein; This family includes export proteins involved in ...
 323-391 3.36e-03

Capsule polysaccharide biosynthesis protein; This family includes export proteins involved in capsule polysaccharide biosynthesis, such as KpsS and LipB.


Pssm-ID: 282949  Cd Length: 310  Bit Score: 39.45  E-value: 3.36e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 255767797  323 QLQIIIKPHP--------WEIGKNKLDLYHEAAKKHqacrVIKKELELYDLLPYVDAAVTQTSTVGLEAMLFQKPVL 391
Cdd:pfam05159 187 DSNIIIKTHPddrggikyRRIIKGYATQLPGFKRRV----LYIDDGNLPSLLDHVDGVVTVNSTAGFEALLHGKPVV 259
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 376-460 4.66e-03

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 37.28  E-value: 4.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255767797 376 TSTVGLEAMLFQKPVLIGKSSGNRsypyyESLGD----FMFDQ--PDELAHTLVEVLRSPDVHQKAEEARLAFIAANYP- 448
Cdd:COG0438   33 FGLVLLEAMAAGLPVIATDVGGLP-----EVIEDgetgLLVPPgdPEALAEAILRLLEDPELRRRLGEAARERAEERFSw 107

                         90
                 ....*....|....
gi 255767797 449 --VAESTNALFAEL 460
Cdd:COG0438  108 eaIAERLLALYEEL 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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