NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15600150|ref|NP_253644|]
View 

phosphatidylserine decarboxylase [Pseudomonas aeruginosa PAO1]

Protein Classification

phosphatidylserine decarboxylase( domain architecture ID 10011131)

phosphatidylserine decarboxylase catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)

EC:  4.1.1.65
Gene Ontology:  GO:0006646|GO:0004609
PubMed:  1495415|32402247|33707636
SCOP:  4007787

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 3-288 0e+00

phosphatidylserine decarboxylase; Reviewed


:

Pssm-ID: 234591  Cd Length: 288  Bit Score: 564.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    3 FKDRLFICSQYLLPHHLLSRLIGFAADCRATWFKDRLIAWFARRYQVDMREAQVEDLQAFEHFNAFFTRALKDGARPLAQ 82
Cdd:PRK00044   1 MLDRLKILLQYLLPKHLLTRLAGWLASSRAGWLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   83 EPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYV 162
Cdd:PRK00044  81 DPNALVSPADGAISQLGPIEDGQIFQAKGHSYSLEALLGGDAALADPFRNGSFATIYLSPRDYHRVHMPCDGTLREMIYV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  163 PGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKR-ELKTFRYDEAARAPIRL 241
Cdd:PRK00044 161 PGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIETVWAGTVTPPREgIIKRWDYPEAGDGAITL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 15600150  242 EKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLALPKQ 288
Cdd:PRK00044 241 KKGAEMGRFKLGSTVINLFPPGKVQLAEQLQAGSVVRMGQPLAHITE 287
 
Name Accession Description Interval E-value
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 3-288 0e+00

phosphatidylserine decarboxylase; Reviewed


Pssm-ID: 234591  Cd Length: 288  Bit Score: 564.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    3 FKDRLFICSQYLLPHHLLSRLIGFAADCRATWFKDRLIAWFARRYQVDMREAQVEDLQAFEHFNAFFTRALKDGARPLAQ 82
Cdd:PRK00044   1 MLDRLKILLQYLLPKHLLTRLAGWLASSRAGWLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   83 EPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYV 162
Cdd:PRK00044  81 DPNALVSPADGAISQLGPIEDGQIFQAKGHSYSLEALLGGDAALADPFRNGSFATIYLSPRDYHRVHMPCDGTLREMIYV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  163 PGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKR-ELKTFRYDEAARAPIRL 241
Cdd:PRK00044 161 PGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIETVWAGTVTPPREgIIKRWDYPEAGDGAITL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 15600150  242 EKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLALPKQ 288
Cdd:PRK00044 241 KKGAEMGRFKLGSTVINLFPPGKVQLAEQLQAGSVVRMGQPLAHITE 287
Psd COG0688
Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine ...
 16-281 4.17e-113

Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine decarboxylase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440452 [Multi-domain]  Cd Length: 243  Bit Score: 326.04  E-value: 4.17e-113
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  16 PHHLLSRLIGFAADCRaTWFKDRLIAWFARRYQVDMREAQVEDlqaFEHFNAFFTRALKDGARPLAQEPGAVLCPADGAI 95
Cdd:COG0688   1 PKHLLSRLMGPIAREG-WPFIALLIRTFIKRYGIDLSEALPSS---YTSFNDFFFRDLKPGARPIPDDPDAVVSPADGKV 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  96 SQLGPIEHGRIFQAKGHSYSLAELLgGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAE 175
Cdd:COG0688  77 SQIGEIEEDRLLQAKGHPYSLEELL-GDSELAEKFEGGTFVSIFLSPFDYHRNHMPVDGTVVEVKYIPGKFLSVNPLALR 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150 176 nvPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAglvtppkrelktfrydeaarAPIRLEKGAELGRFKLGST 255
Cdd:COG0688 156 --PKLFARNERVVIVIETEFGPVAVVQVGALIVRRIVTYVK--------------------EGDTLKKGEEMGLFKFGST 213

                       250       260
                ....*....|....*....|....*.
gi 15600150 256 AIVLFGPQQVAFNdgLGAASPVRMGE 281
Cdd:COG0688 214 VDLLLPKGAVEIL--VKPGQKVRAGE 237
PS_decarb TIGR00163
phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as ...
 51-284 1.64e-99

phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 272936 [Multi-domain]  Cd Length: 238  Bit Score: 291.35  E-value: 1.64e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    51 MREAQVEDLQAFEHFNAFFTRALKDGARPLAQEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPF 130
Cdd:TIGR00163   1 LDEAEKPDLADYRSLNEFFIRPLKLERRPVDKEPNALVSPADGVISEVGIINPNQILQVKGMDYSLEELLGEKNPLSPYF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   131 M-GGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVA 209
Cdd:TIGR00163  81 RnGGFFVVTYLSPRDYHRFHSPCDCRLRKMRYFPGDLFSVNPLGLQNVPNLFVRNERVILVFDTEFGNMLMIPVGATNVG 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600150   210 SIETVWAGLVTPPKRELKTFRYDEAARAPIRLEKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLA 284
Cdd:TIGR00163 161 SIRTNFDGNIQTNPRHEFTQTWTYNALGPVKLLKGEEMGYFELGSTVILLFEADAFQLSAHLAVGQEVKIGELLA 235
PS_Dcarbxylase pfam02666
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 65-281 1.10e-79

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


Pssm-ID: 396989 [Multi-domain]  Cd Length: 198  Bit Score: 239.49  E-value: 1.10e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    65 FNAFFTRALKDGARPLAQEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAelAAPFMGGDFATVYLSPRD 144
Cdd:pfam02666   1 LNAFFTRFLRDPARPIPAGPGAVVSPADGKISEIGEIEDDSVIQVKGVTYSLRELLGDDK--LDKFKGGTFIVIYLSPFD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   145 YHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVwaglvtppkr 224
Cdd:pfam02666  79 YHRNHAPVDGTVKEVRYIPGKLLPVNPAALKEIPNLFALNERVVLVIETTDGKVAVVQVGALNVGSIVLT---------- 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15600150   225 elktfrydeaARAPIRLEKGAELGRFKLGSTAIVLFgPQQVAFNDGLGAASPVRMGE 281
Cdd:pfam02666 149 ----------VKPGDEVKKGEELGYFKFGSTVVLLF-PKGKFFEDLVEPGQKVKAGE 194
 
Name Accession Description Interval E-value
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 3-288 0e+00

phosphatidylserine decarboxylase; Reviewed


Pssm-ID: 234591  Cd Length: 288  Bit Score: 564.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    3 FKDRLFICSQYLLPHHLLSRLIGFAADCRATWFKDRLIAWFARRYQVDMREAQVEDLQAFEHFNAFFTRALKDGARPLAQ 82
Cdd:PRK00044   1 MLDRLKILLQYLLPKHLLTRLAGWLASSRAGWLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   83 EPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYV 162
Cdd:PRK00044  81 DPNALVSPADGAISQLGPIEDGQIFQAKGHSYSLEALLGGDAALADPFRNGSFATIYLSPRDYHRVHMPCDGTLREMIYV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  163 PGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKR-ELKTFRYDEAARAPIRL 241
Cdd:PRK00044 161 PGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIETVWAGTVTPPREgIIKRWDYPEAGDGAITL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 15600150  242 EKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLALPKQ 288
Cdd:PRK00044 241 KKGAEMGRFKLGSTVINLFPPGKVQLAEQLQAGSVVRMGQPLAHITE 287
PRK09629 PRK09629
bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional
 2-289 3.00e-175

bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional


Pssm-ID: 104071 [Multi-domain]  Cd Length: 610  Bit Score: 497.33  E-value: 3.00e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    2 SFKDRLFICSQYLLPHHLLSRLIGFAADCRATWFKDRLIAWFARRYQVDMREAQVEDLQAFEHFNAFFTRALKDGARPLA 81
Cdd:PRK09629 323 SMKDRLFIISQYLLPHHLLSRLAGCVAECRVRWFKNAFTAWFARRYQVDMSQALVEDLTSYEHFNAFFTRALKADARPLD 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   82 QEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVY 161
Cdd:PRK09629 403 TTPGAILSPADGAISQLGPIDHGRIFQAKGHSFSVLELLGGDPKLSAPFMGGEFATVYLSPKDYHRVHMPLAGTLREMVY 482

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  162 VPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGLVTPPKRELKTFRYDEAARAPIRL 241
Cdd:PRK09629 483 VPGRIFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASVETVWAGLVTPPKRELKTFSYDEAARAPIHL 562

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 15600150  242 EKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLALPKQS 289
Cdd:PRK09629 563 EKGAEMGRFKLGSTAIVLFGPNQVKWAEQLTAGSKVQMGQALAVPAQA 610
Psd COG0688
Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine ...
 16-281 4.17e-113

Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine decarboxylase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440452 [Multi-domain]  Cd Length: 243  Bit Score: 326.04  E-value: 4.17e-113
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  16 PHHLLSRLIGFAADCRaTWFKDRLIAWFARRYQVDMREAQVEDlqaFEHFNAFFTRALKDGARPLAQEPGAVLCPADGAI 95
Cdd:COG0688   1 PKHLLSRLMGPIAREG-WPFIALLIRTFIKRYGIDLSEALPSS---YTSFNDFFFRDLKPGARPIPDDPDAVVSPADGKV 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  96 SQLGPIEHGRIFQAKGHSYSLAELLgGDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAE 175
Cdd:COG0688  77 SQIGEIEEDRLLQAKGHPYSLEELL-GDSELAEKFEGGTFVSIFLSPFDYHRNHMPVDGTVVEVKYIPGKFLSVNPLALR 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150 176 nvPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAglvtppkrelktfrydeaarAPIRLEKGAELGRFKLGST 255
Cdd:COG0688 156 --PKLFARNERVVIVIETEFGPVAVVQVGALIVRRIVTYVK--------------------EGDTLKKGEEMGLFKFGST 213

                       250       260
                ....*....|....*....|....*.
gi 15600150 256 AIVLFGPQQVAFNdgLGAASPVRMGE 281
Cdd:COG0688 214 VDLLLPKGAVEIL--VKPGQKVRAGE 237
PS_decarb TIGR00163
phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as ...
 51-284 1.64e-99

phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 272936 [Multi-domain]  Cd Length: 238  Bit Score: 291.35  E-value: 1.64e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    51 MREAQVEDLQAFEHFNAFFTRALKDGARPLAQEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAELAAPF 130
Cdd:TIGR00163   1 LDEAEKPDLADYRSLNEFFIRPLKLERRPVDKEPNALVSPADGVISEVGIINPNQILQVKGMDYSLEELLGEKNPLSPYF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   131 M-GGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVA 209
Cdd:TIGR00163  81 RnGGFFVVTYLSPRDYHRFHSPCDCRLRKMRYFPGDLFSVNPLGLQNVPNLFVRNERVILVFDTEFGNMLMIPVGATNVG 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600150   210 SIETVWAGLVTPPKRELKTFRYDEAARAPIRLEKGAELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLA 284
Cdd:TIGR00163 161 SIRTNFDGNIQTNPRHEFTQTWTYNALGPVKLLKGEEMGYFELGSTVILLFEADAFQLSAHLAVGQEVKIGELLA 235
PS_Dcarbxylase pfam02666
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 65-281 1.10e-79

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


Pssm-ID: 396989 [Multi-domain]  Cd Length: 198  Bit Score: 239.49  E-value: 1.10e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    65 FNAFFTRALKDGARPLAQEPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAelAAPFMGGDFATVYLSPRD 144
Cdd:pfam02666   1 LNAFFTRFLRDPARPIPAGPGAVVSPADGKISEIGEIEDDSVIQVKGVTYSLRELLGDDK--LDKFKGGTFIVIYLSPFD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   145 YHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVwaglvtppkr 224
Cdd:pfam02666  79 YHRNHAPVDGTVKEVRYIPGKLLPVNPAALKEIPNLFALNERVVLVIETTDGKVAVVQVGALNVGSIVLT---------- 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15600150   225 elktfrydeaARAPIRLEKGAELGRFKLGSTAIVLFgPQQVAFNDGLGAASPVRMGE 281
Cdd:pfam02666 149 ----------VKPGDEVKKGEELGYFKFGSTVVLLF-PKGKFFEDLVEPGQKVKAGE 194
PRK03140 PRK03140
phosphatidylserine decarboxylase; Provisional
 6-284 1.71e-55

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 179544 [Multi-domain]  Cd Length: 259  Bit Score: 179.80  E-value: 1.71e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150    6 RLFIcsqYLLPHHLLSRLIgfAADCRATWFKdRLIAWFARRYQVDMREAQvEDLQAFEHFNAFFTRALKDGARPLAQEPG 85
Cdd:PRK03140   7 RLLI---ELTNGRFTSYLL--RKFAQSRLSS-ILIPSYAKVYQINQDEME-KGLKEYRTLHELFTRKLKEGKRPIDTDAS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   86 AVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDaELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGR 165
Cdd:PRK03140  80 SIVSPVDGVFADVGPIEDDKTFDVKGKRYSIAEMLGNE-ERAQRYAGGTYMVLYLSPSHYHRIHSPISGTVTEQFVLGRK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  166 LFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIETVWAGlvtppkrelktfrydeaarapIRLEKGA 245
Cdd:PRK03140 159 SYPVNALGLEYGKRPLSKNYRSVTEVNSDGEHMALVKVGAMFVNSIELTHER---------------------DTVQKGE 217

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 15600150  246 ELGRFKLGSTAIVLFGPQQVAFNDGLGAASPVRMGECLA 284
Cdd:PRK03140 218 EMAYFSFGSTVVLLFEKDMIEPDQELKSGQEVRLGEKIG 256
PRK03934 PRK03934
phosphatidylserine decarboxylase; Provisional
 19-284 1.67e-50

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 235177 [Multi-domain]  Cd Length: 265  Bit Score: 167.43  E-value: 1.67e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   19 LLSRLIG-FAADCRATWFKDRLIAWFARRYQVDMREaqVEDLQAFEHFNAFFTRALKDgARPLAQEPGAVLCPADGAISQ 97
Cdd:PRK03934   6 ALSRIFGkFAGYKFPKFIQKFINASYVKIFKIDMSE--FKPPENYKSLNALFTRSLKK-PREFDEDPNIFISPCDSLITE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   98 LGPIEHGRIFQAKGHSYSLAELLG-GDAELAApfmGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAEN 176
Cdd:PRK03934  83 CGSLEEDKALQIKGMEYSIEELLGeSNSELVN---GFDYINFYLSPKDYHRYHAPCDLEILEARYIPGKLYPVNLPSLEK 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  177 VPELFARNERVVCLFDTERGPMAV-VLVGAMIVASIETVWAGLV-TPPK-RELKTFRYDeaaraPIRLEKGAELGRFKLG 253
Cdd:PRK03934 160 NKNLFVKNERVVLKCKDKKGKRLYfVFVGALNVGKMRFNFDERIqTNAKaRFIQTYEYE-----NLKLKKGEELGNFEMG 234

                        250       260       270
                 ....*....|....*....|....*....|.
gi 15600150  254 STAIVLFGPQQVAFNDGLGAAspVRMGECLA 284
Cdd:PRK03934 235 STIVLFSQKGSLEFNLKAGKS--VKFGESIG 263
PRK00723 PRK00723
phosphatidylserine decarboxylase; Provisional
 19-281 9.39e-50

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 179097 [Multi-domain]  Cd Length: 297  Bit Score: 166.25  E-value: 9.39e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   19 LLSRLIGFAADCRATWFKdrlIAWFARRYQVDMREA--QVEDlqaFEHFNAFFTRALKDGARPLAQEPGAVLCPADGAIS 96
Cdd:PRK00723  44 IFSKIYGWYCDSRLSRKK---IKPFVNDFNIDMSESekPLSD---FKSFNDFFTRKLKPEARPIDQGENILISPGDGRLL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   97 QLGPIEHGRIFQAKGHSYSLAELLGgDAELAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAEN 176
Cdd:PRK00723 118 AYENIDLNSLFQVKGKTYSLKELLG-DPELAKKYAGGTCLILRLCPTDYHRFHFPDSGICEETRKIKGHYYSVNPIALKK 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  177 VPELFARNERVVCLFDTER-GPMAVVLVGAMIVASIetvwaglvtppkreLKTFRYDEaarapiRLEKGAELGRFKL-GS 254
Cdd:PRK00723 197 IFELFCENKREWSIFKSENfGDILYVEVGATCVGSI--------------IQTYKPNK------KVKKGDEKGYFKFgGS 256

                        250       260       270
                 ....*....|....*....|....*....|...
gi 15600150  255 TAIVLFGPQQVAF------NDGLGAASPVRMGE 281
Cdd:PRK00723 257 TVILFFEKNKIKIdadileQSKLGYETKVLMGE 289
PLN02938 PLN02938
phosphatidylserine decarboxylase
 14-283 6.57e-34

phosphatidylserine decarboxylase


Pssm-ID: 178526  Cd Length: 428  Bit Score: 127.63  E-value: 6.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   14 LLPHHLLSRLIG-FAADCRATWFKDRLIAWFARRYQVDMREAQVEdLQAFEHFNAFFTRALKDGARPLAQEPGAVLCPAD 92
Cdd:PLN02938  93 LLPLRSISRLWGsLTSVELPVWMRPYVYKAWARAFHSNLEEAALP-LEEYASLREFFVRSLKEGARPIDPDPNCLVSPVD 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   93 GAISQLGPIEH--GRIFQAKGHSYSLAELLGGDAEL--------------------------------------AAPFMG 132
Cdd:PLN02938 172 GIVLRFGELKGpgTMIEQVKGFSYSVSALLGANSLLpmtaegkeekeeetlkdksskswlrvslaspklrdpvsASPMKG 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  133 GDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASIE 212
Cdd:PLN02938 252 LFYCVIYLGPGDYHRIHSPSDWNIEVRRHFSGRLFPVNERATRTIRNLYVENERVVLEGEWQEGFMAMAAVGATNIGSIE 331

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  213 -TVWAGLVT--PPKRELKTFRYDEAARAP----IRLEKGAELGRFKLGSTAIVLF------GPQQVAFNDGLG------- 272
Cdd:PLN02938 332 lFIEPELRTnrPKKKIFNSEPPEERVYEPegcgLCLKKGDEVAVFNLGSTVVLVFeapvevEPLFKVLDQSSSdfrfcvr 411

                        330
                 ....*....|.
gi 15600150  273 AASPVRMGECL 283
Cdd:PLN02938 412 KGDRIRVGQAL 422
PLN02964 PLN02964
phosphatidylserine decarboxylase
 48-275 2.09e-30

phosphatidylserine decarboxylase


Pssm-ID: 215520 [Multi-domain]  Cd Length: 644  Bit Score: 119.96  E-value: 2.09e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   48 QVDMREAQvEDLQAFEHFNAFFTRALKDGARPLAQEPGA--VLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAe 125
Cdd:PLN02964 400 QINMDEVK-YPLEHFKTFNEFFIRELKPGARPIACMDNDdvAVCAADCRLMAFQSVDDSTRFWIKGRKFSIKGLLGKKV- 477

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  126 LAAPFMGGDFATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNqTTAENVP--ELFARNERVVCLFDT-ERGPMAVVL 202
Cdd:PLN02964 478 HSDAFLDGSLVIFRLAPQDYHRFHVPVSGVIEKFVDVPGSLYTVN-PIAVNSKycNVFTENKRAVCIISTaEFGKVAFVA 556

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15600150  203 VGAMIVASIetvwaglvtppkrelkTFRYDEAArapiRLEKGAELGRFKLG-STAIVLFGPQQVAFNDGLGAAS 275
Cdd:PLN02964 557 IGATMVGSI----------------TFVKKEGD----HVKKGDELGYFSFGgSTVICVFEKDAIDIDEDLLANS 610
PTZ00403 PTZ00403
phosphatidylserine decarboxylase; Provisional
 59-278 1.39e-17

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 173594  Cd Length: 353  Bit Score: 81.44  E-value: 1.39e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   59 LQAFEHFNAFFTRALKDGARPLAQ-EPGAVLCPADGAISQLGPIEHGRIFQAKGHSYSLAELLGGDAelaaPFMGGD--- 134
Cdd:PTZ00403 104 IESYKSIGDFFSRYIREETRPIGDvSDYSIVSPCDSELTDYGELSSEYLENVKGVKFNVNTFLGSDM----QKKYNDgst 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  135 ---FATVYLSPRDYHRVHMPLAGTLREMVYVPGRLFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASI 211
Cdd:PTZ00403 180 kffYAIFYLSPKKYHHFHAPFNFKYKIRRHISGELFPVFQGMFKIINNLFNINERVILSGEWKGGNVYYAAISAYNVGNI 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150  212 ETVW-AGLVTPPKR----------ELKTF-RYDEaarapirLEKGAELGRFKLGSTAIVLFGP-----------QQVAFN 268
Cdd:PTZ00403 260 KIINdEELVTNNLRtqlsymggdiNTKIYdSYKS-------VEVGDEVGEFRMGSSIVVIFENkknfswnvkpnQTVSVG 332

                        250
                 ....*....|
gi 15600150  269 DGLGAASPVR 278
Cdd:PTZ00403 333 QRLGGVGEPV 342
PRK05305 PRK05305
phosphatidylserine decarboxylase family protein;
65-208 5.66e-07

phosphatidylserine decarboxylase family protein;


Pssm-ID: 235400 [Multi-domain]  Cd Length: 206  Bit Score: 49.02  E-value: 5.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600150   65 FNAFFTRalkDGARPLAQEPGAVLCPADGAISQLGPIEHgrifqakghsyslaELLGGDAELAAPFMggdfatvylSPRD 144
Cdd:PRK05305  37 FCLYFFR---DPERVIPTDDGLVVSPADGKVVVIEEVVP--------------PYGDEPRLRISIFM---------SVFN 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600150  145 YHRVHMPLAGTLREMVYVPGRLFSVNQTTAEnvpelfARNERVVCLFDTERG-PMAVVLV-GAM---IV 208
Cdd:PRK05305  91 VHVNRAPVSGTVTKVEYRPGKFLNAFLDKAS------EENERNAVVIETADGgEIGVVQIaGLIarrIV 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH