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Conserved domains on  [gi|15232969|ref|NP_191645|]
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SEC7-like guanine nucleotide exchange family protein [Arabidopsis thaliana]

Protein Classification

ARF family guanine-nucleotide exchange factor( domain architecture ID 11477399)

ARF family guanine-nucleotide exchange factor activates ARF proteins by exchanging bound GDP for free GTP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03076 PLN03076
ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
 1-1793 0e+00

ARF guanine nucleotide exchange factor (ARF-GEF); Provisional


:

Pssm-ID: 215560 [Multi-domain]  Cd Length: 1780  Bit Score: 3429.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     1 MASSEADSRLSRVVTPALEKIVKNASWRKHSKLANECKAVIERLNSLQKSPPPSSSAATDSESESSVPGPLNDGGSIEYS 80
Cdd:PLN03076    1 MASSEADSRLGKVVSPALEKIIKNASWRKHSKLAHECKAVIERLNSPEKNPPSTSSAAADSASASSLPGPLHDGGSIEYS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    81 LADSELIFSPLINACGTGLAKIIEPAIDCIQKLIAHGYIRGESDPSGGAESLLLFKLIDSVCKCHDLGDESIELPVLKTL 160
Cdd:PLN03076   81 LAESELILSPLINACGTGSAKIVDPALDCIQKLIAHGYLRGEADPSGGPEALLLAKLIESVCKCHDLGDEGIELLVLKTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   161 LSAINSISLRIHGKCLLLVVRTCYDIYLGSKNVVNQTTAKASLIQILVIVFRRMEADSSTVPIQPIVVAELMEPLEKSDA 240
Cdd:PLN03076  161 LSAVTSTSLRIHGDCLLQAVRTCYDIYLGSKNVVNQTTAKASLIQMLVIVFRRMEADSSTVPIQPIVVAELMEPAEKSDS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   241 DGTMTQFVQGFITKIMQDIDGVLNPTMSGSGSGSGSggQDGAYGTTTVETTNP-TDLLDSTDKDMLDAKYWEISMYKSAL 319
Cdd:PLN03076  241 DTSMTQFVQGFITKIMQDIDGVLNPATAGKSSGSGA--HDGAFETTATVETTNpADLLDSTDKDMLDAKYWEISMYKSAL 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   320 EGRKGELTDGDAERDDDLEVQIENKLRRDACLVFRALCKLSMKAPPKESSADPQSMRGKILALELLKILLENAGAVFRTS 399
Cdd:PLN03076  319 EGRKGELADGEVEKDDDLEVQIGNKLRRDAFLVFRALCKLSMKTPPKEALADPQLMRGKILALELLKILLENAGAVFRTS 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   400 EKFSADIKQFLCLSLLKNSASTLMIIFQLSCSIFISLVARFRAGLKAEIGVFFPMIVLRVVENVAQPNFQQKMIVLRFLD 479
Cdd:PLN03076  399 DRFLGAIKQYLCLSLLKNSASSLMIIFQLSCSIFISLVSRFRAGLKAEIGVFFPMIVLRVLENVAQPNFQQKMIVLRFLD 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   480 KLCLDSQILVDIFLNYDCDVNSSNIFERMVNGLLKTAQGVPPGTATTLMPPQEAAMKLEAMKCLVAILKSMGDWLNKQLR 559
Cdd:PLN03076  479 KLCVDSQILVDIFINYDCDVNSSNIFERMVNGLLKTAQGVPPGVETTLLPPQEAAMKLEAMKCLVAILRSMGDWMNKQLR 558

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   560 LPVSNSLNKSDVIEIDLGPGSPQLANGNADESADGSDTYSESSGGTSDALAIEQRRAYKLELQEGISLFNRKPTKGIEFL 639
Cdd:PLN03076  559 LPDPASLKKLDAVENNLEPGSLPVANGNGDENGEGSDSHSELSSETSDAATIEQRRAYKLELQEGISLFNRKPKKGIEFL 638

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   640 INAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGMEFDEAIRTFLEGFRLPGEAQKIDRI 719
Cdd:PLN03076  639 INANKVGESPEEIAAFLKDASGLNKTLIGDYLGEREDLSLKVMHAYVDSFDFQGMEFDEAIRAFLQGFRLPGEAQKIDRI 718

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   720 MEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPADYMRSLYERITKHEI 799
Cdd:PLN03076  719 MEKFAERYCKCNPKAFSSADTAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPEEFMRSLYERISKNEI 798

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   800 KMKEDDLRLQQKQYANSNRMLGLDGILNIVIRKQWGDSYAETSDDLMKHMQEQFKEKARKSESTYYAATDVVILRFMIEA 879
Cdd:PLN03076  799 KMKEDDLVPQQKQSANSNRILGLDSILNIVIRKRGEDSYMETSDDLIKHMQEQFKEKARKSESVYYAATDVVILRFMVEV 878

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   880 CWAPMLAAFSVPLDQSDDLIVINICLEGFHHAIHATSLMSMKTHRDAFVTSLAKFTSLHSPADIKQRNIEAIKAILRLAD 959
Cdd:PLN03076  879 CWAPMLAAFSVPLDQSDDEVVTFQCLEGFRHAIHVTAVMSMKTHRDAFVTSLAKFTSLHSPADIKQKNIDAIKAIVSIAD 958

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   960 EEGNYLQDAWEHILTCVSRFEQLHLLGEGAPPDATFFASKQNESEKSKQPKQYILPVLKRKGPGKSQYAATGVLRGSYDS 1039
Cdd:PLN03076  959 EDGNYLQEAWEHILTCVSRFEHLHLLGEGAPPDATFFAAPQNESDKSKQAKSPILPVLKRKGPGKLQYAAAAVRRGSYDS 1038

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1040 MSLGGKGSKNVRQEQMSSIVSNLNLLEQVG--EMNQVFSQSQKLNSEAIIDFVKALCKVSMDELRSPSNPRVFSLTKIVE 1117
Cdd:PLN03076 1039 AGVGGKASGVVTSEQMNNLVSNLNMLEQVGsfEMNRIFTRSQKLNSEAIIDFVKALCKVSMEELRSPSDPRVFSLTKIVE 1118

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1118 IAHYNMNRIRLVWSSIWQVLSGFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMTPFVIVMRRSNDVE 1197
Cdd:PLN03076 1119 IAHYNMNRIRLVWSSIWHVLSDFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMKPFVIVMRKSNAVE 1198

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1198 IRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVFLSFEIIEKIIREYFPYITETETTTFTDCVNCLVAFT 1277
Cdd:PLN03076 1199 IRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVLLAFEIIEKIIREYFPYITETETTTFTDCVNCLIAFT 1278

                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1278 NNRFSKDISLSSIAFLRYCATKLAEGDLNSPSTNKYKGTsgkiPQSSLHSGKSGKQENGEIVN-NNHLYFWFPLLSGLSE 1356
Cdd:PLN03076 1279 NSRFNKDISLNAIAFLRFCATKLAEGDLGSSSRNKDKEA----PPSSPQSGKDGKQESGEFTDkDDHLYFWFPLLAGLSE 1354

                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1357 LSFDPRPEIRKSALQIMFDTLRNHGHLFSLPLWEKVFESVLFPIFDYVRHSIDPSGEDESADQGsSGGEVDELDHDAWLY 1436
Cdd:PLN03076 1355 LSFDPRPEIRKSALQVLFDTLRNHGHLFSLPLWERVFESVLFPIFDYVRHAIDPSGGDEPEGQG-VDGDQGELDQDAWLY 1433

                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1437 ETCTLALQLVVDLFVKFYTTVNPLLEKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSDADGLFSEEKWLEVVSALKEAAKT 1516
Cdd:PLN03076 1434 ETCTLALQLVVDLFVKFYPTVNPLLKKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSNAGHLFSDEKWLEVVLSLKEAANA 1513

                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1517 TCPDFSYFLSEEYVarsqrSALNIQNSNAESAAPTATDGNEESQRTATHLYAAISDAKCRAAVQLLLIQAVMEIYNMYRP 1596
Cdd:PLN03076 1514 TLPDFSYVVSGEYM-----PAENIQDSENAEAASSSTADNDAEAERSRRLYAAISDAKCRAAVQLLLIQAVMEIYNMYRP 1588

                        1610      1620      1630      1640      1650      1660      1670      1680
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1597 QLSAKNTLVLVDALHGVALHAHGINSNTILRSRLQELGPMTQMQDPPLLRLENESYQICLTFLQNLVADKTKKeeeEEEE 1676
Cdd:PLN03076 1589 RLSAKNTLVLFDALHTVASHAHKINSDTALRSKLQELGSMTQMQDPPLLRLENESYQICLTFLQNLILDKPPL---AKEA 1665

                        1690      1700      1710      1720      1730      1740      1750      1760
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1677 EIESLLVNICQEVLNFYIETSSSAKklQSESSRASEYRWRIPLGSGKRRELSARAPLIVATLQAMCTLDEASFEKNLKCL 1756
Cdd:PLN03076 1666 EVESRLVELCEEVLQFYIETSTAGQ--DSEDSSSQQPRWLIPLGSGKRRELAARAPLVVATLQAVCGLGDSSFEKNLVRF 1743

                        1770      1780      1790
                  ....*....|....*....|....*....|....*..
gi 15232969  1757 FPLLANLISCEHGSNEVQTALADMLGLSVGPVLLQWC 1793
Cdd:PLN03076 1744 FPLLAGLISCEHGSNEVQVALSDMLSSWVGPVLLQSC 1780
 
Name Accession Description Interval E-value
PLN03076 PLN03076
ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
 1-1793 0e+00

ARF guanine nucleotide exchange factor (ARF-GEF); Provisional


Pssm-ID: 215560 [Multi-domain]  Cd Length: 1780  Bit Score: 3429.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     1 MASSEADSRLSRVVTPALEKIVKNASWRKHSKLANECKAVIERLNSLQKSPPPSSSAATDSESESSVPGPLNDGGSIEYS 80
Cdd:PLN03076    1 MASSEADSRLGKVVSPALEKIIKNASWRKHSKLAHECKAVIERLNSPEKNPPSTSSAAADSASASSLPGPLHDGGSIEYS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    81 LADSELIFSPLINACGTGLAKIIEPAIDCIQKLIAHGYIRGESDPSGGAESLLLFKLIDSVCKCHDLGDESIELPVLKTL 160
Cdd:PLN03076   81 LAESELILSPLINACGTGSAKIVDPALDCIQKLIAHGYLRGEADPSGGPEALLLAKLIESVCKCHDLGDEGIELLVLKTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   161 LSAINSISLRIHGKCLLLVVRTCYDIYLGSKNVVNQTTAKASLIQILVIVFRRMEADSSTVPIQPIVVAELMEPLEKSDA 240
Cdd:PLN03076  161 LSAVTSTSLRIHGDCLLQAVRTCYDIYLGSKNVVNQTTAKASLIQMLVIVFRRMEADSSTVPIQPIVVAELMEPAEKSDS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   241 DGTMTQFVQGFITKIMQDIDGVLNPTMSGSGSGSGSggQDGAYGTTTVETTNP-TDLLDSTDKDMLDAKYWEISMYKSAL 319
Cdd:PLN03076  241 DTSMTQFVQGFITKIMQDIDGVLNPATAGKSSGSGA--HDGAFETTATVETTNpADLLDSTDKDMLDAKYWEISMYKSAL 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   320 EGRKGELTDGDAERDDDLEVQIENKLRRDACLVFRALCKLSMKAPPKESSADPQSMRGKILALELLKILLENAGAVFRTS 399
Cdd:PLN03076  319 EGRKGELADGEVEKDDDLEVQIGNKLRRDAFLVFRALCKLSMKTPPKEALADPQLMRGKILALELLKILLENAGAVFRTS 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   400 EKFSADIKQFLCLSLLKNSASTLMIIFQLSCSIFISLVARFRAGLKAEIGVFFPMIVLRVVENVAQPNFQQKMIVLRFLD 479
Cdd:PLN03076  399 DRFLGAIKQYLCLSLLKNSASSLMIIFQLSCSIFISLVSRFRAGLKAEIGVFFPMIVLRVLENVAQPNFQQKMIVLRFLD 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   480 KLCLDSQILVDIFLNYDCDVNSSNIFERMVNGLLKTAQGVPPGTATTLMPPQEAAMKLEAMKCLVAILKSMGDWLNKQLR 559
Cdd:PLN03076  479 KLCVDSQILVDIFINYDCDVNSSNIFERMVNGLLKTAQGVPPGVETTLLPPQEAAMKLEAMKCLVAILRSMGDWMNKQLR 558

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   560 LPVSNSLNKSDVIEIDLGPGSPQLANGNADESADGSDTYSESSGGTSDALAIEQRRAYKLELQEGISLFNRKPTKGIEFL 639
Cdd:PLN03076  559 LPDPASLKKLDAVENNLEPGSLPVANGNGDENGEGSDSHSELSSETSDAATIEQRRAYKLELQEGISLFNRKPKKGIEFL 638

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   640 INAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGMEFDEAIRTFLEGFRLPGEAQKIDRI 719
Cdd:PLN03076  639 INANKVGESPEEIAAFLKDASGLNKTLIGDYLGEREDLSLKVMHAYVDSFDFQGMEFDEAIRAFLQGFRLPGEAQKIDRI 718

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   720 MEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPADYMRSLYERITKHEI 799
Cdd:PLN03076  719 MEKFAERYCKCNPKAFSSADTAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPEEFMRSLYERISKNEI 798

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   800 KMKEDDLRLQQKQYANSNRMLGLDGILNIVIRKQWGDSYAETSDDLMKHMQEQFKEKARKSESTYYAATDVVILRFMIEA 879
Cdd:PLN03076  799 KMKEDDLVPQQKQSANSNRILGLDSILNIVIRKRGEDSYMETSDDLIKHMQEQFKEKARKSESVYYAATDVVILRFMVEV 878

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   880 CWAPMLAAFSVPLDQSDDLIVINICLEGFHHAIHATSLMSMKTHRDAFVTSLAKFTSLHSPADIKQRNIEAIKAILRLAD 959
Cdd:PLN03076  879 CWAPMLAAFSVPLDQSDDEVVTFQCLEGFRHAIHVTAVMSMKTHRDAFVTSLAKFTSLHSPADIKQKNIDAIKAIVSIAD 958

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   960 EEGNYLQDAWEHILTCVSRFEQLHLLGEGAPPDATFFASKQNESEKSKQPKQYILPVLKRKGPGKSQYAATGVLRGSYDS 1039
Cdd:PLN03076  959 EDGNYLQEAWEHILTCVSRFEHLHLLGEGAPPDATFFAAPQNESDKSKQAKSPILPVLKRKGPGKLQYAAAAVRRGSYDS 1038

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1040 MSLGGKGSKNVRQEQMSSIVSNLNLLEQVG--EMNQVFSQSQKLNSEAIIDFVKALCKVSMDELRSPSNPRVFSLTKIVE 1117
Cdd:PLN03076 1039 AGVGGKASGVVTSEQMNNLVSNLNMLEQVGsfEMNRIFTRSQKLNSEAIIDFVKALCKVSMEELRSPSDPRVFSLTKIVE 1118

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1118 IAHYNMNRIRLVWSSIWQVLSGFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMTPFVIVMRRSNDVE 1197
Cdd:PLN03076 1119 IAHYNMNRIRLVWSSIWHVLSDFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMKPFVIVMRKSNAVE 1198

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1198 IRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVFLSFEIIEKIIREYFPYITETETTTFTDCVNCLVAFT 1277
Cdd:PLN03076 1199 IRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVLLAFEIIEKIIREYFPYITETETTTFTDCVNCLIAFT 1278

                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1278 NNRFSKDISLSSIAFLRYCATKLAEGDLNSPSTNKYKGTsgkiPQSSLHSGKSGKQENGEIVN-NNHLYFWFPLLSGLSE 1356
Cdd:PLN03076 1279 NSRFNKDISLNAIAFLRFCATKLAEGDLGSSSRNKDKEA----PPSSPQSGKDGKQESGEFTDkDDHLYFWFPLLAGLSE 1354

                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1357 LSFDPRPEIRKSALQIMFDTLRNHGHLFSLPLWEKVFESVLFPIFDYVRHSIDPSGEDESADQGsSGGEVDELDHDAWLY 1436
Cdd:PLN03076 1355 LSFDPRPEIRKSALQVLFDTLRNHGHLFSLPLWERVFESVLFPIFDYVRHAIDPSGGDEPEGQG-VDGDQGELDQDAWLY 1433

                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1437 ETCTLALQLVVDLFVKFYTTVNPLLEKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSDADGLFSEEKWLEVVSALKEAAKT 1516
Cdd:PLN03076 1434 ETCTLALQLVVDLFVKFYPTVNPLLKKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSNAGHLFSDEKWLEVVLSLKEAANA 1513

                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1517 TCPDFSYFLSEEYVarsqrSALNIQNSNAESAAPTATDGNEESQRTATHLYAAISDAKCRAAVQLLLIQAVMEIYNMYRP 1596
Cdd:PLN03076 1514 TLPDFSYVVSGEYM-----PAENIQDSENAEAASSSTADNDAEAERSRRLYAAISDAKCRAAVQLLLIQAVMEIYNMYRP 1588

                        1610      1620      1630      1640      1650      1660      1670      1680
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1597 QLSAKNTLVLVDALHGVALHAHGINSNTILRSRLQELGPMTQMQDPPLLRLENESYQICLTFLQNLVADKTKKeeeEEEE 1676
Cdd:PLN03076 1589 RLSAKNTLVLFDALHTVASHAHKINSDTALRSKLQELGSMTQMQDPPLLRLENESYQICLTFLQNLILDKPPL---AKEA 1665

                        1690      1700      1710      1720      1730      1740      1750      1760
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1677 EIESLLVNICQEVLNFYIETSSSAKklQSESSRASEYRWRIPLGSGKRRELSARAPLIVATLQAMCTLDEASFEKNLKCL 1756
Cdd:PLN03076 1666 EVESRLVELCEEVLQFYIETSTAGQ--DSEDSSSQQPRWLIPLGSGKRRELAARAPLVVATLQAVCGLGDSSFEKNLVRF 1743

                        1770      1780      1790
                  ....*....|....*....|....*....|....*..
gi 15232969  1757 FPLLANLISCEHGSNEVQTALADMLGLSVGPVLLQWC 1793
Cdd:PLN03076 1744 FPLLAGLISCEHGSNEVQVALSDMLSSWVGPVLLQSC 1780
Sec7 pfam01369
Sec7 domain; The Sec7 domain is a guanine-nucleotide-exchange-factor (GEF) for the pfam00025 ...
 618-799 1.05e-100

Sec7 domain; The Sec7 domain is a guanine-nucleotide-exchange-factor (GEF) for the pfam00025 family.


Pssm-ID: 460178  Cd Length: 183  Bit Score: 320.56  E-value: 1.05e-100
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    618 KLELQEGISLFNRKPTKGIEFLINAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGMEFD 697
Cdd:pfam01369    2 KKLLREGIEKFNKKPKKGIEYLIEKGFIEDDPESIAKFLFETPGLDKKAIGEYLGKPDEFNIEVLKAFVDLFDFKGLRID 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    698 EAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGID 777
Cdd:pfam01369   82 EALRLFLESFRLPGEAQKIDRIMEAFAERYYEQNPGVFANADAAYVLAYSIIMLNTDLHNPNVKKKMTLEDFIRNLRGIN 161

                          170       180
                   ....*....|....*....|..
gi 15232969    778 DGKDLPADYMRSLYERITKHEI 799
Cdd:pfam01369  162 DGKDFPDEYLEEIYDSIKKNEI 183
Sec7 cd00171
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the ...
 617-799 2.37e-86

Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor activity.


Pssm-ID: 238100  Cd Length: 185  Bit Score: 279.88  E-value: 2.37e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  617 YKLELQEGISLFNRKPTKGIEFLINAGKV-GESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGME 695
Cdd:cd00171    1 RKTLLSEGRQLFNRKPKKGISFLIEKGFLeDDSPKEIAKFLYETEGLNKKAIGEYLGENNEFNSLVLHEFVDLFDFSGLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  696 FDEAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFT-SADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNR 774
Cdd:cd00171   81 LDEALRKFLQSFRLPGEAQKIDRLLEKFSERYCECNPGIFSsSADAAYTLAYSIIMLNTDLHNPNVKKKMTLEDFIKNLR 160

                        170       180
                 ....*....|....*....|....*
gi 15232969  775 GIDDGKDLPADYMRSLYERITKHEI 799
Cdd:cd00171  161 GINDGEDFPREFLKELYDSIKNNEI 185
Sec7 smart00222
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product, which is required for ...
 615-799 2.22e-76

Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product, which is required for proper protein transport through the Golgi. The domain facilitates guanine nucleotide exchange on the small GTPases, ARFs (ADP ribosylation factors).


Pssm-ID: 214569 [Multi-domain]  Cd Length: 189  Bit Score: 251.44  E-value: 2.22e-76
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     615 RAYKLELQEGISLFNRKPTKGIEFLINAGKVG-ESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRG 693
Cdd:smart00222    2 KGRKKLLSEGIVKFNDKPKKGIQSLQEKGFLAnEDPQDVADFLSKNEGLNKKAIGDYLGEHDEFNRLVLHAFVDLFDFSA 81

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     694 MEFDEAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFT--SADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIR 771
Cdd:smart00222   82 KDLDQALREFLESFRLPGEAQKIDRLLEAFSSRYCECNPGVFSkaNADAAYTLAYSLIMLNTDLHNPNVKKKMTLEDFIK 161

                           170       180
                    ....*....|....*....|....*...
gi 15232969     772 NNRGIDDGKDLPADYMRSLYERITKHEI 799
Cdd:smart00222  162 NVRGSNDGEDLPREFLEELYDSIKNNEI 189
 
Name Accession Description Interval E-value
PLN03076 PLN03076
ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
 1-1793 0e+00

ARF guanine nucleotide exchange factor (ARF-GEF); Provisional


Pssm-ID: 215560 [Multi-domain]  Cd Length: 1780  Bit Score: 3429.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     1 MASSEADSRLSRVVTPALEKIVKNASWRKHSKLANECKAVIERLNSLQKSPPPSSSAATDSESESSVPGPLNDGGSIEYS 80
Cdd:PLN03076    1 MASSEADSRLGKVVSPALEKIIKNASWRKHSKLAHECKAVIERLNSPEKNPPSTSSAAADSASASSLPGPLHDGGSIEYS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    81 LADSELIFSPLINACGTGLAKIIEPAIDCIQKLIAHGYIRGESDPSGGAESLLLFKLIDSVCKCHDLGDESIELPVLKTL 160
Cdd:PLN03076   81 LAESELILSPLINACGTGSAKIVDPALDCIQKLIAHGYLRGEADPSGGPEALLLAKLIESVCKCHDLGDEGIELLVLKTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   161 LSAINSISLRIHGKCLLLVVRTCYDIYLGSKNVVNQTTAKASLIQILVIVFRRMEADSSTVPIQPIVVAELMEPLEKSDA 240
Cdd:PLN03076  161 LSAVTSTSLRIHGDCLLQAVRTCYDIYLGSKNVVNQTTAKASLIQMLVIVFRRMEADSSTVPIQPIVVAELMEPAEKSDS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   241 DGTMTQFVQGFITKIMQDIDGVLNPTMSGSGSGSGSggQDGAYGTTTVETTNP-TDLLDSTDKDMLDAKYWEISMYKSAL 319
Cdd:PLN03076  241 DTSMTQFVQGFITKIMQDIDGVLNPATAGKSSGSGA--HDGAFETTATVETTNpADLLDSTDKDMLDAKYWEISMYKSAL 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   320 EGRKGELTDGDAERDDDLEVQIENKLRRDACLVFRALCKLSMKAPPKESSADPQSMRGKILALELLKILLENAGAVFRTS 399
Cdd:PLN03076  319 EGRKGELADGEVEKDDDLEVQIGNKLRRDAFLVFRALCKLSMKTPPKEALADPQLMRGKILALELLKILLENAGAVFRTS 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   400 EKFSADIKQFLCLSLLKNSASTLMIIFQLSCSIFISLVARFRAGLKAEIGVFFPMIVLRVVENVAQPNFQQKMIVLRFLD 479
Cdd:PLN03076  399 DRFLGAIKQYLCLSLLKNSASSLMIIFQLSCSIFISLVSRFRAGLKAEIGVFFPMIVLRVLENVAQPNFQQKMIVLRFLD 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   480 KLCLDSQILVDIFLNYDCDVNSSNIFERMVNGLLKTAQGVPPGTATTLMPPQEAAMKLEAMKCLVAILKSMGDWLNKQLR 559
Cdd:PLN03076  479 KLCVDSQILVDIFINYDCDVNSSNIFERMVNGLLKTAQGVPPGVETTLLPPQEAAMKLEAMKCLVAILRSMGDWMNKQLR 558

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   560 LPVSNSLNKSDVIEIDLGPGSPQLANGNADESADGSDTYSESSGGTSDALAIEQRRAYKLELQEGISLFNRKPTKGIEFL 639
Cdd:PLN03076  559 LPDPASLKKLDAVENNLEPGSLPVANGNGDENGEGSDSHSELSSETSDAATIEQRRAYKLELQEGISLFNRKPKKGIEFL 638

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   640 INAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGMEFDEAIRTFLEGFRLPGEAQKIDRI 719
Cdd:PLN03076  639 INANKVGESPEEIAAFLKDASGLNKTLIGDYLGEREDLSLKVMHAYVDSFDFQGMEFDEAIRAFLQGFRLPGEAQKIDRI 718

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   720 MEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPADYMRSLYERITKHEI 799
Cdd:PLN03076  719 MEKFAERYCKCNPKAFSSADTAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPEEFMRSLYERISKNEI 798

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   800 KMKEDDLRLQQKQYANSNRMLGLDGILNIVIRKQWGDSYAETSDDLMKHMQEQFKEKARKSESTYYAATDVVILRFMIEA 879
Cdd:PLN03076  799 KMKEDDLVPQQKQSANSNRILGLDSILNIVIRKRGEDSYMETSDDLIKHMQEQFKEKARKSESVYYAATDVVILRFMVEV 878

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   880 CWAPMLAAFSVPLDQSDDLIVINICLEGFHHAIHATSLMSMKTHRDAFVTSLAKFTSLHSPADIKQRNIEAIKAILRLAD 959
Cdd:PLN03076  879 CWAPMLAAFSVPLDQSDDEVVTFQCLEGFRHAIHVTAVMSMKTHRDAFVTSLAKFTSLHSPADIKQKNIDAIKAIVSIAD 958

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   960 EEGNYLQDAWEHILTCVSRFEQLHLLGEGAPPDATFFASKQNESEKSKQPKQYILPVLKRKGPGKSQYAATGVLRGSYDS 1039
Cdd:PLN03076  959 EDGNYLQEAWEHILTCVSRFEHLHLLGEGAPPDATFFAAPQNESDKSKQAKSPILPVLKRKGPGKLQYAAAAVRRGSYDS 1038

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1040 MSLGGKGSKNVRQEQMSSIVSNLNLLEQVG--EMNQVFSQSQKLNSEAIIDFVKALCKVSMDELRSPSNPRVFSLTKIVE 1117
Cdd:PLN03076 1039 AGVGGKASGVVTSEQMNNLVSNLNMLEQVGsfEMNRIFTRSQKLNSEAIIDFVKALCKVSMEELRSPSDPRVFSLTKIVE 1118

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1118 IAHYNMNRIRLVWSSIWQVLSGFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMTPFVIVMRRSNDVE 1197
Cdd:PLN03076 1119 IAHYNMNRIRLVWSSIWHVLSDFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMKPFVIVMRKSNAVE 1198

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1198 IRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVFLSFEIIEKIIREYFPYITETETTTFTDCVNCLVAFT 1277
Cdd:PLN03076 1199 IRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVLLAFEIIEKIIREYFPYITETETTTFTDCVNCLIAFT 1278

                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1278 NNRFSKDISLSSIAFLRYCATKLAEGDLNSPSTNKYKGTsgkiPQSSLHSGKSGKQENGEIVN-NNHLYFWFPLLSGLSE 1356
Cdd:PLN03076 1279 NSRFNKDISLNAIAFLRFCATKLAEGDLGSSSRNKDKEA----PPSSPQSGKDGKQESGEFTDkDDHLYFWFPLLAGLSE 1354

                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1357 LSFDPRPEIRKSALQIMFDTLRNHGHLFSLPLWEKVFESVLFPIFDYVRHSIDPSGEDESADQGsSGGEVDELDHDAWLY 1436
Cdd:PLN03076 1355 LSFDPRPEIRKSALQVLFDTLRNHGHLFSLPLWERVFESVLFPIFDYVRHAIDPSGGDEPEGQG-VDGDQGELDQDAWLY 1433

                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1437 ETCTLALQLVVDLFVKFYTTVNPLLEKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSDADGLFSEEKWLEVVSALKEAAKT 1516
Cdd:PLN03076 1434 ETCTLALQLVVDLFVKFYPTVNPLLKKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSNAGHLFSDEKWLEVVLSLKEAANA 1513

                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1517 TCPDFSYFLSEEYVarsqrSALNIQNSNAESAAPTATDGNEESQRTATHLYAAISDAKCRAAVQLLLIQAVMEIYNMYRP 1596
Cdd:PLN03076 1514 TLPDFSYVVSGEYM-----PAENIQDSENAEAASSSTADNDAEAERSRRLYAAISDAKCRAAVQLLLIQAVMEIYNMYRP 1588

                        1610      1620      1630      1640      1650      1660      1670      1680
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1597 QLSAKNTLVLVDALHGVALHAHGINSNTILRSRLQELGPMTQMQDPPLLRLENESYQICLTFLQNLVADKTKKeeeEEEE 1676
Cdd:PLN03076 1589 RLSAKNTLVLFDALHTVASHAHKINSDTALRSKLQELGSMTQMQDPPLLRLENESYQICLTFLQNLILDKPPL---AKEA 1665

                        1690      1700      1710      1720      1730      1740      1750      1760
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  1677 EIESLLVNICQEVLNFYIETSSSAKklQSESSRASEYRWRIPLGSGKRRELSARAPLIVATLQAMCTLDEASFEKNLKCL 1756
Cdd:PLN03076 1666 EVESRLVELCEEVLQFYIETSTAGQ--DSEDSSSQQPRWLIPLGSGKRRELAARAPLVVATLQAVCGLGDSSFEKNLVRF 1743

                        1770      1780      1790
                  ....*....|....*....|....*....|....*..
gi 15232969  1757 FPLLANLISCEHGSNEVQTALADMLGLSVGPVLLQWC 1793
Cdd:PLN03076 1744 FPLLAGLISCEHGSNEVQVALSDMLSSWVGPVLLQSC 1780
Sec7 pfam01369
Sec7 domain; The Sec7 domain is a guanine-nucleotide-exchange-factor (GEF) for the pfam00025 ...
 618-799 1.05e-100

Sec7 domain; The Sec7 domain is a guanine-nucleotide-exchange-factor (GEF) for the pfam00025 family.


Pssm-ID: 460178  Cd Length: 183  Bit Score: 320.56  E-value: 1.05e-100
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    618 KLELQEGISLFNRKPTKGIEFLINAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGMEFD 697
Cdd:pfam01369    2 KKLLREGIEKFNKKPKKGIEYLIEKGFIEDDPESIAKFLFETPGLDKKAIGEYLGKPDEFNIEVLKAFVDLFDFKGLRID 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    698 EAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGID 777
Cdd:pfam01369   82 EALRLFLESFRLPGEAQKIDRIMEAFAERYYEQNPGVFANADAAYVLAYSIIMLNTDLHNPNVKKKMTLEDFIRNLRGIN 161

                          170       180
                   ....*....|....*....|..
gi 15232969    778 DGKDLPADYMRSLYERITKHEI 799
Cdd:pfam01369  162 DGKDFPDEYLEEIYDSIKKNEI 183
Sec7 cd00171
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the ...
 617-799 2.37e-86

Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor activity.


Pssm-ID: 238100  Cd Length: 185  Bit Score: 279.88  E-value: 2.37e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  617 YKLELQEGISLFNRKPTKGIEFLINAGKV-GESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGME 695
Cdd:cd00171    1 RKTLLSEGRQLFNRKPKKGISFLIEKGFLeDDSPKEIAKFLYETEGLNKKAIGEYLGENNEFNSLVLHEFVDLFDFSGLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969  696 FDEAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFT-SADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNR 774
Cdd:cd00171   81 LDEALRKFLQSFRLPGEAQKIDRLLEKFSERYCECNPGIFSsSADAAYTLAYSIIMLNTDLHNPNVKKKMTLEDFIKNLR 160

                        170       180
                 ....*....|....*....|....*
gi 15232969  775 GIDDGKDLPADYMRSLYERITKHEI 799
Cdd:cd00171  161 GINDGEDFPREFLKELYDSIKNNEI 185
Sec7 smart00222
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product, which is required for ...
 615-799 2.22e-76

Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product, which is required for proper protein transport through the Golgi. The domain facilitates guanine nucleotide exchange on the small GTPases, ARFs (ADP ribosylation factors).


Pssm-ID: 214569 [Multi-domain]  Cd Length: 189  Bit Score: 251.44  E-value: 2.22e-76
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     615 RAYKLELQEGISLFNRKPTKGIEFLINAGKVG-ESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRG 693
Cdd:smart00222    2 KGRKKLLSEGIVKFNDKPKKGIQSLQEKGFLAnEDPQDVADFLSKNEGLNKKAIGDYLGEHDEFNRLVLHAFVDLFDFSA 81

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     694 MEFDEAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFT--SADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIR 771
Cdd:smart00222   82 KDLDQALREFLESFRLPGEAQKIDRLLEAFSSRYCECNPGVFSkaNADAAYTLAYSLIMLNTDLHNPNVKKKMTLEDFIK 161

                           170       180
                    ....*....|....*....|....*...
gi 15232969     772 NNRGIDDGKDLPADYMRSLYERITKHEI 799
Cdd:smart00222  162 NVRGSNDGEDLPREFLEELYDSIKNNEI 189
DCB pfam16213
dimerization and cyclophilin-binding domain of Mon2; DCB is the N-terminal domain of Mon2- and ...
 6-214 1.77e-39

dimerization and cyclophilin-binding domain of Mon2; DCB is the N-terminal domain of Mon2- and GIG1-like proteins from metazoa. Mon2 and BIG1 like proteins play an important role in the cytoplasm-to-vacuole transport pathway and are required for Golgi homeostasis.


Pssm-ID: 465072 [Multi-domain]  Cd Length: 172  Bit Score: 145.09  E-value: 1.77e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969      6 ADSRLSRVVTPALEKIvKNASWRKHSKLANECKAVIERLNSLQKSPPPSSSAatdsesessvpgplndggsieysLADSE 85
Cdd:pfam16213    1 QGSKLLEALQSDLRTL-SSEAKRKYPPVKEASEKGILRLRTVHSSSPLMQNL-----------------------LSASE 56

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969     86 LIFSPLINACGTGLAKIIEPAIDCIQKLIAHGYIRGESDPsggaeslllfKLIDSVCKCHDLGDEsIELPVLKTLLSAIN 165
Cdd:pfam16213   57 DILKPFVLACETKNPKLVQIALGCLQKLISHDAISQSAAP----------YILDTLWMLMELGSE-IELKVLQTVLLLIT 125

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 15232969    166 SISlRIHGKCLLLVVRTCYDIYLgSKNVVNQTTAKASLIQILVIVFRRM 214
Cdd:pfam16213  126 TNS-VIHGDTLAKALVLCFRLHF-SKDPTVQNTASATLRQLVSVVFERV 172
Sec7_N pfam12783
Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 ...
 345-500 7.84e-39

Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 functions proximally in the secretory pathway as a protein binding scaffold for the coat protein complexes COPII-COPI. The COPII-COPI-protein switch is necessary for maturation of the vesicular-tubular cluster, VTC, intermediate compartments for Golgi compartment biogenesis. This N-terminal domain however does not appear to be binding either of the COP or the ARF.


Pssm-ID: 463703  Cd Length: 154  Bit Score: 142.25  E-value: 7.84e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969    345 LRRDACLVFRALCKLSMKAPPKESSADPQSMRGKILALELLKILLENAGAVFRTSEKFSADIKQFLCLSLLKNSASTLMI 424
Cdd:pfam12783    1 AAKDAFLVFRDLCKLSNGKPLSKSDPKSHAERSKLFSLELIESILENHGDVFLKHPELLQLLKQYLCPSLLRNLSSSSFP 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15232969    425 IFQLSCSIFISLVARFRAGLKAEIGVFFPMIVLRVVENVAqpNFQQKMIVLRFLDKLCLDSQILVDIFLNYDCDVN 500
Cdd:pfam12783   81 VFVRSLRIFLLLLRRFRSHLKLEIEVFLSLLILPLLESDS--SLWQKALVLEVLRRLCSDPQLLVEIYLNYDCDLG 154
BIG2_C pfam20252
BIG2 C-terminal domain; This presumed domain is found at the C-terminus of BIG2 the brefeldin ...
 1578-1781 2.94e-38

BIG2 C-terminal domain; This presumed domain is found at the C-terminus of BIG2 the brefeldin A-inhibited guanine nucleotide-exchange protein. The function of this region is unknown.


Pssm-ID: 466403  Cd Length: 178  Bit Score: 141.61  E-value: 2.94e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   1578 AVQLLLIQAVMEIYNMYRPQLSAKNTLVLVDALHGVALHAHGINSNTILRSRLQELGPMTQMqdPPLLRLENESYQICLT 1657
Cdd:pfam20252    1 VVQLLLIQTVNEILDEHYESLPSDHLLRLLDCLEKSYTFARSFNSDLELRTALWRAGFMKQL--PNLLKQETSSLSTYLR 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   1658 FLQNLVADKTKKeeEEEEEEIESLLVNICQEVLNFYIETSSSAKKlqsessraseyrwriplgsgkrRELSARAPLIVAT 1737
Cdd:pfam20252   79 ILFRLYADDEPR--TSQREEVEERLIPLCEDILEYYLSLDEEEKQ----------------------RELAAWTPVVVLI 134

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 15232969   1738 LQAMCTLDEASFEKNLKCLFPLLANLISCEhGSNEVQTALADML 1781
Cdd:pfam20252  135 LQGLLALPDDDFRRHLPEFYPLLCDLILCE-LSPEVRLALREFF 177
DUF1981 pfam09324
Domain of unknown function (DUF1981); Members of this family of functionally uncharacterized ...
 1166-1249 1.72e-35

Domain of unknown function (DUF1981); Members of this family of functionally uncharacterized domains are found in various plant and yeast protein transport proteins.


Pssm-ID: 462756  Cd Length: 84  Bit Score: 129.92  E-value: 1.72e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   1166 KFLEREELANYNFQNEFMTPFVIVMRRSNDVEIRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVFLSFE 1245
Cdd:pfam09324    1 KFLEKEELSNFKFQKDFLKPFEYIMSNNSSVDVKELVLECILQMIQSKGDNIKSGWKTIFGVLTAAAKDSNESLVRLAFQ 80


                   ....
gi 15232969   1246 IIEK 1249
Cdd:pfam09324   81 ILEL 84
Mon2_C pfam16206
C-terminal region of Mon2 protein; Mon2 proteins are found from fungi to plants, to human and ...
 1346-1473 9.88e-12

C-terminal region of Mon2 protein; Mon2 proteins are found from fungi to plants, to human and is a scaffold protein involved in multiple aspects of endo membrane trafficking. This C-terminal region is essential for Mon2 activity.


Pssm-ID: 465066  Cd Length: 827  Bit Score: 70.15  E-value: 9.88e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15232969   1346 FWFPLLSGLSELSFDPRPEIRKSALQIMFDTLRNHGHLFSLPLWEKVFESVLFPIFDYVRHSiDPSGEDESADQGssGGE 1425
Cdd:pfam16206   92 LWLCLYAKLGELCVDLRPAVRKSAGQTLFSTIGAHGSLLNHPTWHALIWKVLFNLLDNVRAL-SSSADKEKIDAG--GGN 168

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 15232969   1426 VdeLDHDA-------WLyETCTLALQLVVDLFVKFYTTVNPL--LEKVLMLLVSFIK 1473
Cdd:pfam16206  169 I--LIHHSrdtaekqWA-ETQVLTLAGVARIFNTKRELLQMLgdFERAWDLILDFIQ 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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