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Conserved domains on  [gi|15233237|ref|NP_188215|]
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UDP-Glycosyltransferase superfamily protein [Arabidopsis thaliana]

Protein Classification

glycosyltransferase( domain architecture ID 13876812)

glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  16037492|12691742|10521532
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_trans_4_5 pfam16994
Glycosyl-transferase family 4;
234-404 6.13e-91

Glycosyl-transferase family 4;


:

Pssm-ID: 465332  Cd Length: 172  Bit Score: 280.55  E-value: 6.13e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   234 WSRRFVLLFHELSMTGAPISMMELASELLSCGATVYAVVLSRRGGLLQELTRRRIKVVEDKGELSFKTAMKADLVIAGSA 313
Cdd:pfam16994   1 KSKRVVLISHELSMTGAPLALMELATELRSCGATVVVVVLSKGGGLEQELLRRGIKVLPDKGRLSFRTALKADLVIANTA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   314 VCASWIDQYMDHHPAG-GSQIAWWVMENRREYFDRAKPVLDRVKLLIFLSEVQSKQWLTWCEEDHVKLRSQPVIVPLSVN 392
Cdd:pfam16994  81 VCASWIDQYLKEHVAGvLPKVLWWIHENRRHYFDRAKSMLDYVKHLPFLSHSQAEQWLTWTEEELIILMPQTYVVHLSNN 160

                         170
                  ....*....|..
gi 15233237   393 DELAFVAGVSSS 404
Cdd:pfam16994 161 DELYFVAEISVS 172
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 237-691 6.88e-33

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


:

Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 130.35  E-value: 6.88e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 237 RFVLLFHELS--MTGAPISMMELASELLSCGATVYAVVLSRRGGLLQELTRRRIKVVEDKGELSFKT------------A 302
Cdd:cd03801   1 KILLLSPELPppVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRArrllrelrpllrL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 303 MKADLVIAGSAVCASWIDQY---------MDHHPAGGsQIAWWVMENRREYFDRAKPVLDRVKLLIFLSEVQSKqwltWC 373
Cdd:cd03801  81 RKFDVVHAHGLLAALLAALLalllgaplvVTLHGAEP-GRLLLLLAAERRLLARAEALLRRADAVIAVSEALRD----EL 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 374 EEDHVKLRSQPVIVPLSVNDElafvagvssslntptltqetmkekrqKLRESVRTEFGLTDKDMLVMSLSSINPGKGQLL 453
Cdd:cd03801 156 RALGGIPPEKIVVIPNGVDLE--------------------------RFSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDL 209

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 454 LLESVALALEREQtqeqvakrnqskiiknlngirkekislsarhrlrgssrkmkitspavdnhpsvlsatgrrklllsgn 533
Cdd:cd03801 210 LLEALAKLLRRGP------------------------------------------------------------------- 222

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 534 vtqkqDLKLLLgsVGSKSNKVAYVKEMLSflsnngNLSNSVLWTPA--TTRVASLYSAADVYVTNSqgVGETFGRVTIEA 611
Cdd:cd03801 223 -----DVRLVI--VGGDGPLRAELEELEL------GLGDRVRFLGFvpDEELPALYAAADVFVLPS--RYEGFGLVVLEA 287

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 612 MAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNkvLAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVDVL 691
Cdd:cd03801 288 MAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDVEA--LADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
 
Name Accession Description Interval E-value
Glyco_trans_4_5 pfam16994
Glycosyl-transferase family 4;
234-404 6.13e-91

Glycosyl-transferase family 4;


Pssm-ID: 465332  Cd Length: 172  Bit Score: 280.55  E-value: 6.13e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   234 WSRRFVLLFHELSMTGAPISMMELASELLSCGATVYAVVLSRRGGLLQELTRRRIKVVEDKGELSFKTAMKADLVIAGSA 313
Cdd:pfam16994   1 KSKRVVLISHELSMTGAPLALMELATELRSCGATVVVVVLSKGGGLEQELLRRGIKVLPDKGRLSFRTALKADLVIANTA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   314 VCASWIDQYMDHHPAG-GSQIAWWVMENRREYFDRAKPVLDRVKLLIFLSEVQSKQWLTWCEEDHVKLRSQPVIVPLSVN 392
Cdd:pfam16994  81 VCASWIDQYLKEHVAGvLPKVLWWIHENRRHYFDRAKSMLDYVKHLPFLSHSQAEQWLTWTEEELIILMPQTYVVHLSNN 160

                         170
                  ....*....|..
gi 15233237   393 DELAFVAGVSSS 404
Cdd:pfam16994 161 DELYFVAEISVS 172
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 237-691 6.88e-33

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 130.35  E-value: 6.88e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 237 RFVLLFHELS--MTGAPISMMELASELLSCGATVYAVVLSRRGGLLQELTRRRIKVVEDKGELSFKT------------A 302
Cdd:cd03801   1 KILLLSPELPppVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRArrllrelrpllrL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 303 MKADLVIAGSAVCASWIDQY---------MDHHPAGGsQIAWWVMENRREYFDRAKPVLDRVKLLIFLSEVQSKqwltWC 373
Cdd:cd03801  81 RKFDVVHAHGLLAALLAALLalllgaplvVTLHGAEP-GRLLLLLAAERRLLARAEALLRRADAVIAVSEALRD----EL 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 374 EEDHVKLRSQPVIVPLSVNDElafvagvssslntptltqetmkekrqKLRESVRTEFGLTDKDMLVMSLSSINPGKGQLL 453
Cdd:cd03801 156 RALGGIPPEKIVVIPNGVDLE--------------------------RFSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDL 209

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 454 LLESVALALEREQtqeqvakrnqskiiknlngirkekislsarhrlrgssrkmkitspavdnhpsvlsatgrrklllsgn 533
Cdd:cd03801 210 LLEALAKLLRRGP------------------------------------------------------------------- 222

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 534 vtqkqDLKLLLgsVGSKSNKVAYVKEMLSflsnngNLSNSVLWTPA--TTRVASLYSAADVYVTNSqgVGETFGRVTIEA 611
Cdd:cd03801 223 -----DVRLVI--VGGDGPLRAELEELEL------GLGDRVRFLGFvpDEELPALYAAADVFVLPS--RYEGFGLVVLEA 287

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 612 MAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNkvLAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVDVL 691
Cdd:cd03801 288 MAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDVEA--LADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 583-691 8.35e-24

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 96.98  E-value: 8.35e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 583 VASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNkvLAQNLLFLLRNPST 662
Cdd:COG0438  14 LEALLAAADVFVLPS--RSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEA--LAEAILRLLEDPEL 89

                        90       100
                ....*....|....*....|....*....
gi 15233237 663 RLQLGSQGREIVEKMYMKQHMYKRFVDVL 691
Cdd:COG0438  90 RRRLGEAARERAEERFSWEAIAERLLALY 118
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 536-672 8.71e-21

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 89.64  E-value: 8.71e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   536 QKQDLKLLLgsVGSKSNKvayvkEMLSFLSNNGNLSNSVLWTPATTR--VASLYSAADVYVTNSQGvgETFGRVTIEAMA 613
Cdd:pfam00534  30 KNPNLKLVI--AGDGEEE-----KRLKKLAEKLGLGDNVIFLGFVSDedLPELLKIADVFVLPSRY--EGFGIVLLEAMA 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 15233237   614 YGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQNLLFLLRNPSTRLQLGSQGRE 672
Cdd:pfam00534 101 CGLPVIASDVGGPPEVVKDGETGFLVKPNNA--EALAEAIDKLLEDEELRERLGENARK 157
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 574-690 2.14e-13

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 72.45  E-value: 2.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   574 VLWTPAT-TRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQN 652
Cdd:TIGR03088 256 LVWLPGErDDVPALMQALDLFVLPS--LAEGISNTILEAMASGLPVIATAVGGNPELVQHGVTGALVPPGDA--VALARA 331

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 15233237   653 LLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVDV 690
Cdd:TIGR03088 332 LQPYVSDPAARRAHGAAGRARAEQQFSINAMVAAYAGL 369
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 584-676 4.67e-11

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 65.50  E-value: 4.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237  584 ASLYSAADVYVTNSQGvgETFGRVTIEAMAYGLPVLGTDAGGTKEIV---EHNVTGLLHPVG---RAGNKVLAqnllfLL 657
Cdd:PLN02871 326 SQAYASGDVFVMPSES--ETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGdvdDCVEKLET-----LL 398

                         90
                 ....*....|....*....
gi 15233237  658 RNPSTRLQLGSQGREIVEK 676
Cdd:PLN02871 399 ADPELRERMGAAAREEVEK 417
 
Name Accession Description Interval E-value
Glyco_trans_4_5 pfam16994
Glycosyl-transferase family 4;
234-404 6.13e-91

Glycosyl-transferase family 4;


Pssm-ID: 465332  Cd Length: 172  Bit Score: 280.55  E-value: 6.13e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   234 WSRRFVLLFHELSMTGAPISMMELASELLSCGATVYAVVLSRRGGLLQELTRRRIKVVEDKGELSFKTAMKADLVIAGSA 313
Cdd:pfam16994   1 KSKRVVLISHELSMTGAPLALMELATELRSCGATVVVVVLSKGGGLEQELLRRGIKVLPDKGRLSFRTALKADLVIANTA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   314 VCASWIDQYMDHHPAG-GSQIAWWVMENRREYFDRAKPVLDRVKLLIFLSEVQSKQWLTWCEEDHVKLRSQPVIVPLSVN 392
Cdd:pfam16994  81 VCASWIDQYLKEHVAGvLPKVLWWIHENRRHYFDRAKSMLDYVKHLPFLSHSQAEQWLTWTEEELIILMPQTYVVHLSNN 160

                         170
                  ....*....|..
gi 15233237   393 DELAFVAGVSSS 404
Cdd:pfam16994 161 DELYFVAEISVS 172
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 237-691 6.88e-33

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 130.35  E-value: 6.88e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 237 RFVLLFHELS--MTGAPISMMELASELLSCGATVYAVVLSRRGGLLQELTRRRIKVVEDKGELSFKT------------A 302
Cdd:cd03801   1 KILLLSPELPppVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRArrllrelrpllrL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 303 MKADLVIAGSAVCASWIDQY---------MDHHPAGGsQIAWWVMENRREYFDRAKPVLDRVKLLIFLSEVQSKqwltWC 373
Cdd:cd03801  81 RKFDVVHAHGLLAALLAALLalllgaplvVTLHGAEP-GRLLLLLAAERRLLARAEALLRRADAVIAVSEALRD----EL 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 374 EEDHVKLRSQPVIVPLSVNDElafvagvssslntptltqetmkekrqKLRESVRTEFGLTDKDMLVMSLSSINPGKGQLL 453
Cdd:cd03801 156 RALGGIPPEKIVVIPNGVDLE--------------------------RFSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDL 209

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 454 LLESVALALEREQtqeqvakrnqskiiknlngirkekislsarhrlrgssrkmkitspavdnhpsvlsatgrrklllsgn 533
Cdd:cd03801 210 LLEALAKLLRRGP------------------------------------------------------------------- 222

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 534 vtqkqDLKLLLgsVGSKSNKVAYVKEMLSflsnngNLSNSVLWTPA--TTRVASLYSAADVYVTNSqgVGETFGRVTIEA 611
Cdd:cd03801 223 -----DVRLVI--VGGDGPLRAELEELEL------GLGDRVRFLGFvpDEELPALYAAADVFVLPS--RYEGFGLVVLEA 287

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 612 MAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNkvLAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVDVL 691
Cdd:cd03801 288 MAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDVEA--LADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 583-691 8.35e-24

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 96.98  E-value: 8.35e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 583 VASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNkvLAQNLLFLLRNPST 662
Cdd:COG0438  14 LEALLAAADVFVLPS--RSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEA--LAEAILRLLEDPEL 89

                        90       100
                ....*....|....*....|....*....
gi 15233237 663 RLQLGSQGREIVEKMYMKQHMYKRFVDVL 691
Cdd:COG0438  90 RRRLGEAARERAEERFSWEAIAERLLALY 118
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 566-686 3.90e-21

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 95.74  E-value: 3.90e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 566 NNGNLSNSVLWTPATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAg 645
Cdd:cd03808 240 EKLGLEGRIEFLGFRSDVPELLAESDVFVLPS--YREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGVNGFLVPPGDV- 316

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 15233237 646 nKVLAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKR 686
Cdd:cd03808 317 -EALADAIEKLIEDPELRKEMGEAARKRVEEKFDEEKVVNK 356
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 536-672 8.71e-21

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 89.64  E-value: 8.71e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   536 QKQDLKLLLgsVGSKSNKvayvkEMLSFLSNNGNLSNSVLWTPATTR--VASLYSAADVYVTNSQGvgETFGRVTIEAMA 613
Cdd:pfam00534  30 KNPNLKLVI--AGDGEEE-----KRLKKLAEKLGLGDNVIFLGFVSDedLPELLKIADVFVLPSRY--EGFGIVLLEAMA 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 15233237   614 YGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQNLLFLLRNPSTRLQLGSQGRE 672
Cdd:pfam00534 101 CGLPVIASDVGGPPEVVKDGETGFLVKPNNA--EALAEAIDKLLEDEELRERLGENARK 157
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 576-690 9.01e-20

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 91.62  E-value: 9.01e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 576 WTPATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNkvLAQNLLF 655
Cdd:cd03825 250 YIDDDEQLVDIYSAADLFVHPS--LADNLPNTLLEAMACGTPVVAFDTGGSPEIVQHGVTGYLVPPGDVQA--LAEAIEW 325

                        90       100       110
                ....*....|....*....|....*....|....*
gi 15233237 656 LLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVDV 690
Cdd:cd03825 326 LLANPKERESLGERARALAENHFDQRVQAQRYLEL 360
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
536-659 2.42e-18

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 81.79  E-value: 2.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   536 QKQDLKLLLgsVGSksNKVAYVKEMLSflsnngNLSNSVLWTPATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYG 615
Cdd:pfam13692  30 RDNDVRLVI--VGD--GPEEELEELAA------GLEDRVIFTGFVEDLAELLAAADVFVLPS--LYEGFGLKLLEAMAAG 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 15233237   616 LPVLGTDAGGTKEIVeHNVTGLLHPVGRAGNkvLAQNLLFLLRN 659
Cdd:pfam13692  98 LPVVATDVGGIPELV-DGENGLLVPPGDPEA--LAEAILRLLED 138
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 558-689 4.96e-18

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 86.14  E-value: 4.96e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 558 KEMLSFLSNNGNLSNSVLWTPATTRVASLYSAADVYVTNSQGvgETFGRVTIEAMAYGLPVLGTDA-GGTKEIVEHNVTG 636
Cdd:cd03820 224 REELEKLIDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSSRY--EGFPMVLLEAMAYGLPIISFDCpTGPSEIIEDGENG 301

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 15233237 637 LLHPVGRAgnKVLAQNLLFLLRNPSTRLQLGSQGREIVEKmYMKQHMYKRFVD 689
Cdd:cd03820 302 LLVPNGDV--DALAEALLRLMEDEELRKKMGKNARKNAER-FSIEKIIKQWEE 351
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 574-692 1.28e-16

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 81.96  E-value: 1.28e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 574 VLWTPATTR--VASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQ 651
Cdd:cd03814 250 VIFTGFLTGeeLARAYASADVFVFPS--RTETFGLVVLEAMASGLPVVAADAGGPRDIVRPGGTGALVEPGDA--AAFAA 325

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 15233237 652 NLLFLLRNPSTRLQLGSQGREivekmYMKQHMYKRFVDVLV 692
Cdd:cd03814 326 ALRALLEDPELRRRMAARARA-----EAERYSWEAFLDNLL 361
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 582-678 3.33e-15

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 78.05  E-value: 3.33e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 582 RVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLL----HPvgragnKVLAQNLLFLL 657
Cdd:cd03800 295 DLPELYRAADVFVVPS--LYEPFGLTAIEAMACGTPVVATAVGGLQDIVRDGRTGLLvdphDP------EALAAALRRLL 366

                        90       100
                ....*....|....*....|.
gi 15233237 658 RNPSTRLQLGSQGREIVEKMY 678
Cdd:cd03800 367 DDPALWQRLSRAGLERARAHY 387
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 558-642 6.52e-14

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 73.55  E-value: 6.52e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 558 KEMLSFLSNNGNLSNSVLWTPATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGL 637
Cdd:cd03811 231 REELEKLAKELGLAERVIFLGFQSNPYPYLKKADLFVLSS--RYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGENGL 308


                ....*
gi 15233237 638 LHPVG 642
Cdd:cd03811 309 LVPDG 313
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 569-678 6.67e-14

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 73.93  E-value: 6.67e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 569 NLSNSVLWTPATTRVASLYSAADVYVTNSQGvgETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKV 648
Cdd:cd04962 249 GVEDRVLFLGKQDDVEELLSIADLFLLPSEK--ESFGLAALEAMACGVPVVSSNAGGIPEVVKHGETGFLSDVGDV--DA 324

                        90       100       110
                ....*....|....*....|....*....|
gi 15233237 649 LAQNLLFLLRNPSTRLQLGSQGREIVEKMY 678
Cdd:cd04962 325 MAKSALSILEDDELYNRMGRAARKRAAERF 354
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 547-687 2.04e-13

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 73.14  E-value: 2.04e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 547 VGSKSNKVAYVKEMLSfLSNNGNLSNSVLWTpATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGT 626
Cdd:cd03813 330 IGPEDEDPEYAQECKR-LVASLGLENKVKFL-GFQNIKEYYPKLGLLVLTS--ISEGQPLVILEAMASGVPVVATDVGSC 405

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15233237 627 KEIVEhnvtGLLHPVGRAGNKV-------LAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRF 687
Cdd:cd03813 406 RELIY----GADDALGQAGLVVppadpeaLAEALIKLLRDPELRQAFGEAGRKRVEKYYTLEGMIDSY 469
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 574-690 2.14e-13

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 72.45  E-value: 2.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237   574 VLWTPAT-TRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQN 652
Cdd:TIGR03088 256 LVWLPGErDDVPALMQALDLFVLPS--LAEGISNTILEAMASGLPVIATAVGGNPELVQHGVTGALVPPGDA--VALARA 331

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 15233237   653 LLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVDV 690
Cdd:TIGR03088 332 LQPYVSDPAARRAHGAAGRARAEQQFSINAMVAAYAGL 369
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 536-639 3.65e-13

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 69.74  E-value: 3.65e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 536 QKQDLKLLLGSVGSKSNKVAYVKEMLSFLSNNGNlsnsVLWTPATTRVASLYSAADVYVTNSQGvgETFGRVTIEAMAYG 615
Cdd:cd01635 138 RLPDLVLVLVGGGGEREEEEALAAALGLLERVVI----IGGLVDDEVLELLLAAADVFVLPSRS--EGFGLVLLEAMAAG 211

                        90       100
                ....*....|....*....|....
gi 15233237 616 LPVLGTDAGGTKEIVEHNVTGLLH 639
Cdd:cd01635 212 KPVIATDVGGIPEFVVDGENGLLV 235
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 455-678 3.86e-13

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 71.32  E-value: 3.86e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 455 LESVALALEREQTQEQVAKR--NQSKIIKNLNGIRKEKISLSARHRLrgssrKMKiTSPAVDNHPSVLSATGR------- 525
Cdd:cd04951 130 LCDITTNVSREALDEFIAKKafSKNKSVPVYNGIDLNKFKKDINVRL-----KIR-NKLNLKNDEFVILNVGRlteakdy 203

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 526 RKLLLSGNVT--QKQDLKLLLGSVGSKSNKvayvkemLSFLSNNGNLSNSVLWTPATTRVASLYSAADVYVTNSQGvgET 603
Cdd:cd04951 204 PNLLLAISELilSKNDFKLLIAGDGPLRNE-------LERLICNLNLVDRVILLGQISNISEYYNAADLFVLSSEW--EG 274

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15233237 604 FGRVTIEAMAYGLPVLGTDAGGTKEIVE-HNVTGLLHPVGRAGNKVLAqnllFLLRNPSTRLQLGSQgREIVEKMY 678
Cdd:cd04951 275 FGLVVAEAMACERPVVATDAGGVAEVVGdHNYVVPVSDPQLLAEKIKE----IFDMSDEERDILGNK-NEYIAKNF 345
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 583-690 5.03e-13

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 71.26  E-value: 5.03e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 583 VASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQNLLFLLRNPST 662
Cdd:cd03798 270 VPAYYRACDVFVLPS--RHEGFGLVLLEAMACGLPVVATDVGGIPEVVGDPETGLLVPPGDA--DALAAALRRALAEPYL 345

                        90       100       110
                ....*....|....*....|....*....|..
gi 15233237 663 RlQLGSQGREIVEKMY----MKQHMYKRFVDV 690
Cdd:cd03798 346 R-ELGEAARARVAERFswvkAADRIAAAYRDV 376
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 539-689 5.36e-13

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 70.81  E-value: 5.36e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 539 DLKLLL-GSVGSKSNKVAYVKEMLsflsnngnLSNSVLWTPATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLP 617
Cdd:cd03807 221 DLRLLLvGRGPERPNLERLLLELG--------LEDRVHLLGERSDVPALLPAMDIFVLSS--RTEGFPNALLEAMACGLP 290

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15233237 618 VLGTDAGGTKEIVEhNVTGLLHPVGRAGNkvLAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFVD 689
Cdd:cd03807 291 VVATDVGGAAELVD-DGTGFLVPAGDPQA--LADAIRALLEDPEKRARLGRAARERIANEFSIDAMVRRYET 359
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 582-673 2.46e-12

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 68.92  E-value: 2.46e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 582 RVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPvgRAGNKVLAQNLLFLLRNPS 661
Cdd:cd03819 248 DVPAALAASDVVVLPS--LHEEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLLVP--PGDAEALADAIRAAKLLPE 323

                        90
                ....*....|..
gi 15233237 662 TRLQLGSQGREI 673
Cdd:cd03819 324 AREKLQAAAALT 335
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 508-688 2.48e-12

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 69.29  E-value: 2.48e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 508 ITSPAVDNHPSVLSATGRRKLLLSGNVTQKQDLKLLLGS--------------VGSKSNKVAYVKEMLSFLSNNGNLSNS 573
Cdd:cd03794 200 FKPPPKDELRKKLGLDDKFVVVYAGNIGKAQGLETLLEAaerlkrrpdirflfVGDGDEKERLKELAKARGLDNVTFLGR 279

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 574 VLWTpattRVASLYSAADV-YVTNSQGVgETFGRV---TIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVL 649
Cdd:cd03794 280 VPKE----EVPELLSAADVgLVPLKDNP-ANRGSSpskLFEYMAAGKPILASDDGGSDLAVEINGCGLVVEPGDP--EAL 352

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 15233237 650 AQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFV 688
Cdd:cd03794 353 ADAILELLDDPELRRAMGENGRELAEEKFSREKLADRLL 391
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 583-683 2.70e-12

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 68.84  E-value: 2.70e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 583 VASLYSAADVYVTNSQGVGETFGRVTIEAMAYGLPVLGTD-AGGTKEIVEHNVTGLLHPVGRAgnKVLAQNLLFLLRNPS 661
Cdd:cd03795 255 KVIYLHLCDVFVFPSVLRSEAFGIVLLEAMMCGKPVISTNiGTGVPYVNNNGETGLVVPPKDP--DALAEAIDKLLSDEE 332

                        90       100
                ....*....|....*....|..
gi 15233237 662 TRLQLGSQGREIVEKMYMKQHM 683
Cdd:cd03795 333 LRESYGENAKKRFEELFTAEKM 354
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 547-687 2.56e-11

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 65.81  E-value: 2.56e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 547 VGSKSNKVAYVKEMLSFLSNNGNLSNSvlwtpattRVASLYSAADVYVTNSQGvGETFGRVTIEAMAYGLPVLGTDAGGT 626
Cdd:cd03823 226 AGHGPLSDERQIEGGRRIAFLGRVPTD--------DIKDFYEKIDVLVVPSIW-PEPFGLVVREAIAAGLPVIASDLGGI 296

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15233237 627 KEIVEHNVTGLLHPVGRAgnKVLAqNLLFLLRNPSTRLQ-LGSQGREIVEKMYMKQHMYKRF 687
Cdd:cd03823 297 AELIQPGVNGLLFAPGDA--EDLA-AAMRRLLTDPALLErLRAGAEPPRSTESQAEEYLKLY 355
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 584-676 4.67e-11

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 65.50  E-value: 4.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237  584 ASLYSAADVYVTNSQGvgETFGRVTIEAMAYGLPVLGTDAGGTKEIV---EHNVTGLLHPVG---RAGNKVLAqnllfLL 657
Cdd:PLN02871 326 SQAYASGDVFVMPSES--ETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGdvdDCVEKLET-----LL 398

                         90
                 ....*....|....*....
gi 15233237  658 RNPSTRLQLGSQGREIVEK 676
Cdd:PLN02871 399 ADPELRERMGAAAREEVEK 417
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 527-676 7.82e-11

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 64.22  E-value: 7.82e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 527 KLLLSGNVTQKQDLKLLLGSVGSKsnkvAYVKEmLSFLSNNgnlsnsvlwtpattRVASLYSAADVYVTNSqgVGETFGR 606
Cdd:cd03817 233 KLVIVGDGPEREELKELARELGLA----DKVIF-TGFVPRE--------------ELPEYYKAADLFVFAS--TTETQGL 291

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 607 VTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVgraGNKVLAQNLLFLLRNPSTRLQLGSQGREIVEK 676
Cdd:cd03817 292 VYLEAMAAGLPVVAAKDPAASELVEDGENGFLFEP---NDETLAEKLLHLRENLELLRKLSKNAEISARE 358
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 594-678 2.75e-10

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 62.47  E-value: 2.75e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 594 VTNSQGVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQNLLFLLRNPSTRLQLGSQGREI 673
Cdd:cd03799 259 VTAADGDQDGPPNTLKEAMAMGLPVISTEHGGIPELVEDGVSGFLVPERDA--EAIAEKLTYLIEHPAIWPEMGKAGRAR 336


                ....*
gi 15233237 674 VEKMY 678
Cdd:cd03799 337 VEEEY 341
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 576-678 1.48e-09

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 60.54  E-value: 1.48e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 576 WTPATtRVASLYSAADVY----VTNSQGVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnKVLAQ 651
Cdd:cd05844 250 ALPHA-EVQDWMRRAEIFclpsVTAASGDSEGLGIVLLEAAACGVPVVSSRHGGIPEAILDGETGFLVPEGDV--DALAD 326

                        90       100
                ....*....|....*....|....*..
gi 15233237 652 NLLFLLRNPSTRLQLGSQGREIVEKMY 678
Cdd:cd05844 327 ALQALLADRALADRMGGAARAFVCEQF 353
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 602-687 1.60e-09

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 60.30  E-value: 1.60e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 602 ETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLhpvgRAGNKV-LAQNLLFLLRNPSTRLQLGSQGREIVEKMYMK 680
Cdd:cd03805 310 EHFGIVPLEAMYAGKPVIACNSGGPLETVVEGVTGFL----CEPTPEaFAEAMLKLANDPDLADRMGAAGRKRVKEKFSR 385


                ....*..
gi 15233237 681 QHMYKRF 687
Cdd:cd03805 386 EAFAERL 392
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 515-676 9.34e-09

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 57.76  E-value: 9.34e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 515 NHPSVLSATGRRKlllsgnvTQKQDLKLLLgsVGSKSNKVAYVKEMLsflsNNGNLSNSVLWT--PATTRVASLYSAADV 592
Cdd:cd03809 206 NHERLLKAFALLK-------KQGGDLKLVI--VGGKGWEDEELLDLV----KKLGLGGRVRFLgyVSDEDLPALYRGARA 272

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 593 YVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIvehnvtgllhpVGRAGNKV-------LAQNLLFLLRNPSTRLQ 665
Cdd:cd03809 273 FVFPS--LYEGFGLPVLEAMACGTPVIASNISVLPEV-----------AGDAALYFdpldpesIADAILRLLEDPSLREE 339

                       170
                ....*....|.
gi 15233237 666 LGSQGREIVEK 676
Cdd:cd03809 340 LIRKGLERAKK 350
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
534-691 1.04e-08

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 57.88  E-value: 1.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237  534 VTQKQDLKLLLgsVG-----SKSNKVAYVKEMLSFLSNNGNLSNsVLWTPATTRVASLYSAADVYVTNSQgVGETFGRVT 608
Cdd:PRK15484 219 ATAHSNLKLVV--VGdptasSKGEKAAYQKKVLEAAKRIGDRCI-MLGGQPPEKMHNYYPLADLVVVPSQ-VEEAFCMVA 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237  609 IEAMAYGLPVLGTDAGGTKEIVEHNVTG--LLHPVgraGNKVLAQNLLFLLRNPStRLQLGSQGREIVEKMYMKQHMYKR 686
Cdd:PRK15484 295 VEAMAAGKPVLASTKGGITEFVLEGITGyhLAEPM---TSDSIISDINRTLADPE-LTQIAEQAKDFVFSKYSWEGVTQR 370


                 ....*
gi 15233237  687 FVDVL 691
Cdd:PRK15484 371 FEEQI 375
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 569-686 1.01e-07

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 54.23  E-value: 1.01e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 569 NLSNSVLWTPATTRVASLYSAADVYVTNSQGvgETFGRVTIEAMAYGLPVLGTDAG-GTKEIVEHNVTGLLHPVGRAGNk 647
Cdd:cd04949 214 HLEDNVFLKGYHSNLDQEYQDAYLSLLTSQM--EGFGLTLMEAIGHGLPVVSYDVKyGPSELIEDGENGYLIEKNNIDA- 290

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 15233237 648 vLAQNLLFLLRNPSTRLQLGSQGREIVEKmYMKQHMYKR 686
Cdd:cd04949 291 -LADKIIELLNDPEKLQQFSEESYKIAEK-YSTENVMEK 327
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 586-674 2.56e-07

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 53.48  E-value: 2.56e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 586 LYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgnkvLAQNLLFLLRNPSTRLQ 665
Cdd:cd03792 276 LQRAATVVLQLS--TREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGFLVNSVEG----AAVRILRLLTDPELRRK 349


                ....*....
gi 15233237 666 LGSQGREIV 674
Cdd:cd03792 350 MGLAAREHV 358
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 602-638 4.10e-07

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 52.68  E-value: 4.10e-07
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 15233237 602 ETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLL 638
Cdd:cd03802 251 EPFGLVMIEAMACGTPVIAYRRGGLPEVIQHGETGFL 287
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 569-674 4.11e-07

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 52.76  E-value: 4.11e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 569 NLSNSVLWTPATT--RVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAgn 646
Cdd:cd03821 259 GLGDRVTFTGPLYgeAKWALYASADLFVLPS--YSENFGNVVAEALACGLPVVITDKCGLSELVEAGCGVVVDPNVSS-- 334

                        90       100
                ....*....|....*....|....*...
gi 15233237 647 kvLAQNLLFLLRNPSTRLQLGSQGREIV 674
Cdd:cd03821 335 --LAEALAEALRDPADRKRLGEMARRAR 360
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 537-688 1.05e-06

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 51.69  E-value: 1.05e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 537 KQDLKLLlgsVGSKSNKVAYvkEMLSFLSNNGnlsnsvlwtpattrVASLY--SAADVYV--TNSQGVgetfgRVTI-EA 611
Cdd:cd04946 269 KERLEKL---AENKLENVKV--NFTGEVSNKE--------------VKQLYkeNDVDVFVnvSESEGI-----PVSImEA 324

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15233237 612 MAYGLPVLGTDAGGTKEIVEHNVTGLLhPVGRAGNKVLAQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFV 688
Cdd:cd04946 325 ISFGIPVIATNVGGTREIVENETNGLL-LDKDPTPNEIVSSIMKFYLDGGDYKTMKISARECWEERFNAEVNYSKFA 400
PLN00142 PLN00142
sucrose synthase
 548-636 3.00e-05

sucrose synthase


Pssm-ID: 215073 [Multi-domain]  Cd Length: 815  Bit Score: 47.28  E-value: 3.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237  548 GSKSN---KVAYVKEMLSFLsNNGNLSNSVLWTPATT---RVASLYSaadvYVTNSQGV------GETFGRVTIEAMAYG 615
Cdd:PLN00142 616 PSKSKdreEIAEIKKMHSLI-EKYNLKGQFRWIAAQTnrvRNGELYR----YIADTKGAfvqpalYEAFGLTVVEAMTCG 690

                         90       100
                 ....*....|....*....|.
gi 15233237  616 LPVLGTDAGGTKEIVEHNVTG 636
Cdd:PLN00142 691 LPTFATCQGGPAEIIVDGVSG 711
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 602-638 6.43e-05

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 45.74  E-value: 6.43e-05
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 15233237 602 ETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLL 638
Cdd:cd03804 275 EDFGIVPVEAQACGTPVIAFGKGGALETVRPGPTGIL 311
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 570-688 2.14e-04

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 44.64  E-value: 2.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237  570 LSNSVLWTPATTRVASLYSAADVYVTNSQGvgETFGRVTIEAMAYGLPVLGTDAGGTKEIVEHNVTGLLHPVGRAGNKVL 649
Cdd:PRK15179 572 MGERILFTGLSRRVGYWLTQFNAFLLLSRF--EGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEGVTGLTLPADTVTAPDV 649

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 15233237  650 AQNLLFLLRNPSTRLQLGSQGREIVEKMYMKQHMYKRFV 688
Cdd:PRK15179 650 AEALARIHDMCAADPGIARKAADWASARFSLNQMIASTV 688
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 610-678 4.37e-04

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 43.12  E-value: 4.37e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15233237 610 EAMAYGLPVLGTDAGGTKEIVEHNVTGLLhpVGRAGNKVLAQNLLFLLRNPSTRLQLGSQGREIVEKMY 678
Cdd:cd03818 319 EAMACGCPVIGSDTAPVREVIRDGRNGLL--VDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSD 385
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 539-637 1.42e-03

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 41.51  E-value: 1.42e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 539 DLKLLLGSVGSKSNKV-AYVKEMlsflsnngNLSNSVLWTPATTRVASLYSAADVYVTNSqgVGETFGRVTIEAMAYGLP 617
Cdd:cd03812 222 NVKLVLVGEGELKEKIkEKVKEL--------GLEDKVIFLGFRNDVSEILSAMDVFLFPS--LYEGLPLVAVEAQASGLP 291

                        90       100
                ....*....|....*....|
gi 15233237 618 VLGTDAGGTKEIVEHNVTGL 637
Cdd:cd03812 292 CLLSDTITKECDITNNVEFL 311
KdtA COG1519
3-deoxy-D-manno-octulosonic-acid transferase [Cell wall/membrane/envelope biogenesis]; ...
 584-677 2.48e-03

3-deoxy-D-manno-octulosonic-acid transferase [Cell wall/membrane/envelope biogenesis]; 3-deoxy-D-manno-octulosonic-acid transferase is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441128 [Multi-domain]  Cd Length: 424  Bit Score: 40.89  E-value: 2.48e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15233237 584 ASLYSAADV-YVtnsqgvGETFGRV----TIEAMAYGLPVL-G-------------TDAGGTKEIvehnvtgllhpvgrA 644
Cdd:COG1519 314 GLLYALADVaFV------GGSLVPRgghnPLEPAALGKPVLfGphtfnfaeaaellIAAGAAIQV--------------A 373

                        90       100       110
                ....*....|....*....|....*....|...
gi 15233237 645 GNKVLAQNLLFLLRNPSTRLQLGSQGREIVEKM 677
Cdd:COG1519 374 DAEELAAAVLALLADPELRAAMGAAARAVVEAN 406
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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