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Conserved domains on  [gi|42569479|ref|NP_180624|]
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ATP-dependent caseinolytic (Clp) protease/crotonase family protein [Arabidopsis thaliana]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
1-375 0e+00

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02988:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 381  Bit Score: 653.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKW 80
Cdd:PLN02988   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIEQGNW 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFF 160
Cdd:PLN02988  85 RLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFF 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  161 GEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSK 240
Cdd:PLN02988 165 GEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAYHRLDVIDRCFSR 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  241 RTMEEIISALERETTQELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGDLSKDLVEGCR 320
Cdd:PLN02988 245 RTVEEIISALEREATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFVEGCR 324
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 42569479  321 AILIDKDRNPKWEPRRLEDMKDSMVDQFFERVEEEERWEDLKLSPRNNLHALRIA 375
Cdd:PLN02988 325 AILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEEWDDLKLPPRNNLPALAIA 379
 
Name Accession Description Interval E-value
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-375 0e+00

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 653.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKW 80
Cdd:PLN02988   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIEQGNW 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFF 160
Cdd:PLN02988  85 RLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFF 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  161 GEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSK 240
Cdd:PLN02988 165 GEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAYHRLDVIDRCFSR 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  241 RTMEEIISALERETTQELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGDLSKDLVEGCR 320
Cdd:PLN02988 245 RTVEEIISALEREATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFVEGCR 324
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 42569479  321 AILIDKDRNPKWEPRRLEDMKDSMVDQFFERVEEEERWEDLKLSPRNNLHALRIA 375
Cdd:PLN02988 325 AILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEEWDDLKLPPRNNLPALAIA 379
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
15-349 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 512.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    15 VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQNMVQGKWRLGADFFRDQYTL 93
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGeRAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    94 NYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFGEYVGLTGARLDG 173
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   174 AELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSKRTMEEIISALERE 253
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   254 TtqELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGdlsKDLVEGCRAILIDKDRNPKWE 333
Cdd:pfam16113 241 A--DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRR---PDFVEGVRALLIDKDRNPKWS 315
                         330
                  ....*....|....*.
gi 42569479   334 PRRLEDMKDSMVDQFF 349
Cdd:pfam16113 316 PATLEEVTDEMVDAYF 331
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
7-200 1.23e-57

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 186.23  E-value: 1.23e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGkwRLGADF 86
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAG--EEARAF 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  87 FRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF-FGEYVG 165
Cdd:cd06558  79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPaRARELL 158
                       170       180       190
                ....*....|....*....|....*....|....*
gi 42569479 166 LTGARLDGAELLACGLATHFVPSTRLTALETDLCK 200
Cdd:cd06558 159 LTGRRISAEEALELGLVDEVVPDEELLAAALELAR 193
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-195 1.18e-47

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 162.26  E-value: 1.18e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVppvvqNMVQGKWRL--GA 84
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADL-----KELAAAADPeeAR 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  85 DFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF-FGEY 163
Cdd:COG1024  76 AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLaRAKE 155
                       170       180       190
                ....*....|....*....|....*....|....
gi 42569479 164 VGLTGARLDGAELLACGLATHFVPSTRL--TALE 195
Cdd:COG1024 156 LLLTGRRIDAEEALELGLVNRVVPDDELlaAALA 189
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
18-200 2.37e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.50  E-value: 2.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    18 LTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDvppvvqNMVQGKWrlGADFFRDQYTLNY- 95
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGdKAFCSGGD------QKVRGDY--GYIDDSGVHRLNVl 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    96 ----VMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG-FFGEYVGLTGAR 170
Cdd:TIGR01929  88 dvqrQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGqKKAREIWFLCRQ 167
                         170       180       190
                  ....*....|....*....|....*....|
gi 42569479   171 LDGAELLACGLATHFVPSTRLTALETDLCK 200
Cdd:TIGR01929 168 YDAKQALDMGLVNTVVPLADLEKETVRWCR 197
 
Name Accession Description Interval E-value
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-375 0e+00

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 653.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKW 80
Cdd:PLN02988   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIEQGNW 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFF 160
Cdd:PLN02988  85 RLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFF 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  161 GEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSK 240
Cdd:PLN02988 165 GEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAYHRLDVIDRCFSR 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  241 RTMEEIISALERETTQELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGDLSKDLVEGCR 320
Cdd:PLN02988 245 RTVEEIISALEREATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFVEGCR 324
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 42569479  321 AILIDKDRNPKWEPRRLEDMKDSMVDQFFERVEEEERWEDLKLSPRNNLHALRIA 375
Cdd:PLN02988 325 AILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEEWDDLKLPPRNNLPALAIA 379
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
15-349 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 512.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    15 VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQNMVQGKWRLGADFFRDQYTL 93
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGeRAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    94 NYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFGEYVGLTGARLDG 173
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   174 AELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSKRTMEEIISALERE 253
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   254 TtqELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGdlsKDLVEGCRAILIDKDRNPKWE 333
Cdd:pfam16113 241 A--DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRR---PDFVEGVRALLIDKDRNPKWS 315
                         330
                  ....*....|....*.
gi 42569479   334 PRRLEDMKDSMVDQFF 349
Cdd:pfam16113 316 PATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
3-349 3.03e-137

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 394.57  E-value: 3.03e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    3 SQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQNMVQGKWR 81
Cdd:PRK05617   1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGeRGFCAGGDIRALYEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   82 LGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFG 161
Cdd:PRK05617  81 AADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  162 EYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPS-FVSTILDAYTQHPhlKQKSAYHRLDVIDRCFSK 240
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPA--PASELAAQRAWIDECFAG 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  241 RTMEEIISALERETtqelDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGDlskDLVEGCR 320
Cdd:PRK05617 239 DTVEDIIAALEADG----GEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSP---DFVEGVR 311
                        330       340
                 ....*....|....*....|....*....
gi 42569479  321 AILIDKDRNPKWEPRRLEDMKDSMVDQFF 349
Cdd:PRK05617 312 AVLIDKDRNPKWSPATLEDVTPEDVEAFF 340
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
1-349 1.81e-134

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 389.16  E-value: 1.81e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQ------VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVppvvqN 74
Cdd:PLN02874   1 MAQQVQnpaeevVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDL-----K 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   75 MVQGKwRLGADFFRD----QYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGAS 150
Cdd:PLN02874  76 MFYDG-RESDDSCLEvvyrMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFS 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  151 YFLSRLPGFFGEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHR 230
Cdd:PLN02874 155 YILSRLPGHLGEYLALTGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFSKDVQADEDSILNK 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  231 LDVIDRCFSKRTMEEIISALERETTQELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGD 310
Cdd:PLN02874 235 QSWINECFSKDTVEEIIKAFESEASKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNILRST 314
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 42569479  311 LSKDLVEGCRAILIDKDRNPKWEPRRLEDMKDSMVDQFF 349
Cdd:PLN02874 315 VSDDVYEGIRALVIDKDNAPKWNPSTLDEVTDEKVDLVF 353
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
4-349 1.71e-129

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 377.40  E-value: 1.71e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    4 QSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLG 83
Cdd:PLN02851  41 QDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGRAFCSGADVVSLYHLINEGNVEEC 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   84 ADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFGEY 163
Cdd:PLN02851 121 KLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGYLGEY 200
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  164 VGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSKRTM 243
Cdd:PLN02851 201 LALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQYGDLVYPDKSSVLHKIETIDKCFGHDTV 280
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  244 EEIISALERETTQELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRM-VCHVMKGdLSKDLVEGCRAI 322
Cdd:PLN02851 281 EEIIEALENEAASSYDEWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLAREYRIsLCGVSKW-VSGDFCEGVRAR 359
                        330       340
                 ....*....|....*....|....*..
gi 42569479  323 LIDKDRNPKWEPRRLEDMKDSMVDQFF 349
Cdd:PLN02851 360 LVDKDFAPKWDPPSLGEVSKDMVDCYF 386
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
6-369 4.13e-119

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 350.91  E-value: 4.13e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    6 QVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLGAD 85
Cdd:PLN02157  38 QVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIRE 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   86 FFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFGEYVG 165
Cdd:PLN02157 118 FFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLG 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  166 LTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSKRTMEE 245
Cdd:PLN02157 198 LTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESCLEKCAEVAHPEKTGVIRRIDLLEKCFSHDTVEE 277
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  246 IISALERETTQELDDWSLTTIRALKKSSPSSLKISLRSIREGRLQGVGHCLTREYRMVCHVMKGDLSKDLVEGCRAILID 325
Cdd:PLN02157 278 IIDSLEIEAGRRKDTWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLIGPMSGNFCEGVRARLID 357
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 42569479  326 KDRNPKWEPRRLEDMKDSMVDQFFERVEEEERWEDLKLSPRNNL 369
Cdd:PLN02157 358 KDEAPKWDPPSLEKVSEDMVDDYFCALTPTEPDLDLPVKLRESI 401
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
7-200 1.23e-57

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 186.23  E-value: 1.23e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGkwRLGADF 86
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAG--EEARAF 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  87 FRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF-FGEYVG 165
Cdd:cd06558  79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPaRARELL 158
                       170       180       190
                ....*....|....*....|....*....|....*
gi 42569479 166 LTGARLDGAELLACGLATHFVPSTRLTALETDLCK 200
Cdd:cd06558 159 LTGRRISAEEALELGLVDEVVPDEELLAAALELAR 193
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-195 1.18e-47

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 162.26  E-value: 1.18e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVppvvqNMVQGKWRL--GA 84
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADL-----KELAAAADPeeAR 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  85 DFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF-FGEY 163
Cdd:COG1024  76 AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLaRAKE 155
                       170       180       190
                ....*....|....*....|....*....|....
gi 42569479 164 VGLTGARLDGAELLACGLATHFVPSTRL--TALE 195
Cdd:COG1024 156 LLLTGRRIDAEEALELGLVNRVVPDDELlaAALA 189
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-193 1.09e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 123.05  E-value: 1.09e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQgkw 80
Cdd:PRK06688   1 MTMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPK--- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 rlGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLpgff 160
Cdd:PRK06688  78 --PPDELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRL---- 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 42569479  161 geyVG--------LTGARLDGAELLACGLATHFVPSTRLTA 193
Cdd:PRK06688 152 ---IGraraaemlLLGEPLSAEEALRIGLVNRVVPAAELDA 189
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
10-187 2.58e-31

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 119.00  E-value: 2.58e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    10 EEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDvppvVQNMVQGKWRLGADF--- 86
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGAD----LKEMYGEGPAHQALYren 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    87 FRDQYTLNYvmaTYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF-FGEYVG 165
Cdd:pfam00378  77 VLDLWTLLY---TCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEML 153
                         170       180
                  ....*....|....*....|..
gi 42569479   166 LTGARLDGAELLACGLATHFVP 187
Cdd:pfam00378 154 LLGRRISAQEALKWGLVDKVVP 175
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
7-218 1.46e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 114.86  E-value: 1.46e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQNMVQGKWRLGAD 85
Cdd:PRK05980   5 VLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGdRAFSAGADIHEFSASVAAGADVALRD 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   86 FFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF-FGEYV 164
Cdd:PRK05980  85 FVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRkRALEL 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 42569479  165 GLTGARLDGAELLACGLATHFVPSTRLTALETDLCK-VGSSDPSFVSTILDAYTQ 218
Cdd:PRK05980 165 LLTGDAFSAERALEIGLVNAVVPHEELLPAARALARrIIRHSPVAVAAILTAVTR 219
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
7-218 2.06e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 106.21  E-value: 2.06e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQgkwrLGADf 86
Cdd:PRK06190   6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGDGSA----YGAQ- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTLNYVmATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASyflSRLPGFFGEY--- 163
Cdd:PRK06190  81 DALPNPSPAW-PAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLS---VRLPQKVGIGrar 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479  164 -VGLTGARLDGAELLACGLATHFVPSTRL--TALE--TDlckVGSSDPSFVSTILDAYTQ 218
Cdd:PRK06190 157 rMSLTGDFLDAADALRAGLVTEVVPHDELlpRARRlaAS---IAGNNPAAVRALKASYDD 213
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
7-158 3.75e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 102.55  E-value: 3.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNmvqgkwrLGADF 86
Cdd:PRK06072   2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPD-------FAIDL 74
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42569479   87 FRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG 158
Cdd:PRK06072  75 RETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG 146
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
13-191 1.81e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 97.88  E-value: 1.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   13 SSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVqNMVQGKWRLGADFFRDqy 91
Cdd:PRK07657  12 PHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGeKAFCAGADLKERA-GMNEEQVRHAVSLIRT-- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   92 TLNYVmATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRL--PGFFGEYVgLTGA 169
Cdd:PRK07657  89 TMEMV-EQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLigVGRAKELI-YTGR 166
                        170       180
                 ....*....|....*....|..
gi 42569479  170 RLDGAELLACGLATHFVPSTRL 191
Cdd:PRK07657 167 RISAQEAKEIGLVEFVVPAHLL 188
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
7-200 6.36e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 96.53  E-value: 6.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDvppvVQNMvqgkwRLGADF 86
Cdd:PRK05995   6 LEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGAD----LNWM-----KKMAGY 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQytlNYVMA-----------TYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSR 155
Cdd:PRK05995  77 SDDE---NRADArrladmlraiyRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRA 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 42569479  156 LP-GFFGEYVgLTGARLDGAELLACGLATHFVPSTRLTALETDLCK 200
Cdd:PRK05995 154 MGeRAARRYF-LTAERFDAAEALRLGLVHEVVPAEALDAKVDELLA 198
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
1-199 7.01e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 96.70  E-value: 7.01e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPpvvQNMVQGK 79
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGeKAFVSGADIS---QFEESRS 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   80 WRLGADFFRDQYTLNY-VMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRL-- 156
Cdd:PRK06127  84 DAEAVAAYEQAVEAAQaALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLvg 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 42569479  157 PGFFGEYVgLTGARLDGAELLACGLATHFVPSTRLTALETDLC 199
Cdd:PRK06127 164 PSAAKDLF-YTARRFDAAEALRIGLVHRVTAADDLETALADYA 205
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
7-195 1.13e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 95.81  E-value: 1.13e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFN-MISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDvppvVQNMV--QGKWRLG 83
Cdd:PRK09245   5 LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAGTAFSSGGN----VKDMRarVGAFGGS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   84 ADFFRDQYTLN---YVMATYS--KPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG 158
Cdd:PRK09245  81 PADIRQGYRHGiqrIPLALYNleVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIG 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 42569479  159 FFGEY-VGLTGARLDGAELLACGLATHFVPSTRL--TALE 195
Cdd:PRK09245 161 MARAAeMAFTGDAIDAATALEWGLVSRVVPADQLlpAARA 200
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
7-191 6.66e-21

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 90.96  E-value: 6.66e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQ-NMVQGK--WRL 82
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGeKAFVAGADISEMKDlNEEEGRkfGLL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   83 GADFFRDQYTLnyvmatySKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRL--PGFF 160
Cdd:PRK05809  86 GNKVFRKLENL-------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIvgPGKA 158
                        170       180       190
                 ....*....|....*....|....*....|.
gi 42569479  161 GEYVgLTGARLDGAELLACGLATHFVPSTRL 191
Cdd:PRK05809 159 KELI-YTGDMINAEEALRIGLVNKVVEPEKL 188
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
15-213 9.00e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 91.22  E-value: 9.00e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   15 VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPP--------VVQNMVQGKWRLGADF 86
Cdd:PRK08260  14 IATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSAggntfdldAPRTPVEADEEDRADP 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQY-------TLnyvmATYS--KPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLp 157
Cdd:PRK08260  94 SDDGVrdgggrvTL----RIFDslKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRL- 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42569479  158 gffgeyVGL--------TGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSFVSTIL 213
Cdd:PRK08260 169 ------VGLqtalewvySGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSPVSVAL 226
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
7-195 1.16e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 90.17  E-value: 1.16e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPpvvqNMVQGKWRLGADF 86
Cdd:PRK05870   5 VLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLT----ALGAAPGRPAEDG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGffGEYVG- 165
Cdd:PRK05870  81 LRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVG--PQVARa 158
                        170       180       190
                 ....*....|....*....|....*....|..
gi 42569479  166 --LTGARLDGAELLACGLATHFVPSTRLTALE 195
Cdd:PRK05870 159 alLFGMRFDAEAAVRHGLALMVADDPVAAALE 190
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
5-181 1.21e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 90.06  E-value: 1.21e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    5 SQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVppvvqNMVQGKWRLGA 84
Cdd:PRK07511   3 AELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNL-----NRLLENRAKPP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   85 DFFRDQY-TLNYVMA---TYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSR-LPGF 159
Cdd:PRK07511  78 SVQAASIdGLHDWIRairAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLPRQ 157
                        170       180
                 ....*....|....*....|..
gi 42569479  160 FGEYVGLTGARLDGAELLACGL 181
Cdd:PRK07511 158 LATELLLEGKPISAERLHALGV 179
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
7-191 1.29e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 90.10  E-value: 1.29e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDvppvVQNMvqgkwrlgADF 86
Cdd:PRK05862   6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGAD----IKEM--------ADL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 -FRDQYTLNYV-----MATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASyflSRLPGFF 160
Cdd:PRK05862  74 sFMDVYKGDYItnwekVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGS---QRLTRAV 150
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 42569479  161 GEY----VGLTGARLDGAELLACGLATHFVPSTRL 191
Cdd:PRK05862 151 GKAkamdLCLTGRMMDAAEAERAGLVSRVVPADKL 185
PLN02888 PLN02888
enoyl-CoA hydratase
7-195 2.49e-20

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 89.43  E-value: 2.49e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVpPVVQNMVQGKwrlgadf 86
Cdd:PLN02888  12 LVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDL-TAAEEVFKGD------- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTLNYV-MATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFF-GEYV 164
Cdd:PLN02888  84 VKDVETDPVAqMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANrAREV 163
                        170       180       190
                 ....*....|....*....|....*....|...
gi 42569479  165 GLTGARLDGAELLACGLATHFVPSTRL--TALE 195
Cdd:PLN02888 164 SLTAMPLTAETAERWGLVNHVVEESELlkKARE 196
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
7-200 4.22e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 88.56  E-value: 4.22e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVppvvqnmvqgKWRL-GA 84
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGdKAFSAGNDL----------KEQAaGG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   85 DFFRDQYTLNYVMATY--SKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGAsyfLSRLPGFFGE 162
Cdd:PRK06494  76 KRGWPESGFGGLTSRFdlDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGG---LHRLPRQIGL 152
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 42569479  163 YVG----LTGARLDGAELLACGLATHFVPSTRL----TALETDLCK 200
Cdd:PRK06494 153 KRAmgmiLTGRRVTAREGLELGFVNEVVPAGELlaaaERWADDILA 198
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
15-208 1.38e-19

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 87.71  E-value: 1.38e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   15 VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLGADFFRDQYTLN 94
Cdd:PRK08258  27 VATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHEIIGPLTKMDMPELLAFTRMTGDLV 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   95 YVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLF-PDVGASYFLSRLpgffgeyVGL------- 166
Cdd:PRK08258 107 KAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRI-------IGQgrasell 179
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 42569479  167 -TGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPSF 208
Cdd:PRK08258 180 yTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGPTF 222
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
9-191 2.41e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 86.61  E-value: 2.41e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    9 VEEKSSVRILTLNRPKQlNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLGADffR 88
Cdd:PRK07658   6 VRVEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQ--L 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   89 DQYTLNYVmATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASyflSRLPgffgEYVG--- 165
Cdd:PRK07658  83 GQVTFERV-EKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGT---QRLP----RYVGkak 154
                        170       180       190
                 ....*....|....*....|....*....|.
gi 42569479  166 -----LTGARLDGAELLACGLATHFVPSTRL 191
Cdd:PRK07658 155 alemmLTSEPITGAEALKWGLVNGVFPEETL 185
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
1-193 3.41e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 86.30  E-value: 3.41e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVE-EKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDvppvvqnMVQGK 79
Cdd:PRK06210   1 DMAYDAVLYEvADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGAD-------MGELQ 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   80 WRLGADFFRDQYTLNYVM---ATYS----------KPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPD 146
Cdd:PRK06210  74 TIDPSDGRRDTDVRPFVGnrrPDYQtryhfltalrKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAE 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 42569479  147 VGASYFLSRLPGFFGEY-VGLTGARLDGAELLACGLATHFVPSTRLTA 193
Cdd:PRK06210 154 HGISWILPRLVGHANALdLLLSARTFYAEEALRLGLVNRVVPPDELME 201
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
1-195 3.46e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 86.26  E-value: 3.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKS--SVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQ----N 74
Cdd:PRK08138   2 MSTATDVVLLERPadGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATagaiE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   75 MVQgkwrlgadffRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLS 154
Cdd:PRK08138  82 MYL----------RHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLV 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 42569479  155 RLPG-FFGEYVGLTGARLDGAELLACGLATHFVP--STRLTALE 195
Cdd:PRK08138 152 RAVGkFKAMRMALTGCMVPAPEALAIGLVSEVVEdeQTLPRALE 195
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
15-193 5.23e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 85.50  E-value: 5.23e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   15 VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNM-------VQGKWRLgADFF 87
Cdd:PRK07468  15 VATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRAQMtadratrIEEARRL-AMML 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   88 RdqyTLNyvmaTYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFGEYVGLT 167
Cdd:PRK07468  94 K---ALN----DLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMS 166
                        170       180
                 ....*....|....*....|....*.
gi 42569479  168 GARLDGAELLACGLATHFVPSTRLTA 193
Cdd:PRK07468 167 ARLFDAEEAVRLGLLSRVVPAERLDA 192
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
7-193 8.62e-19

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 84.99  E-value: 8.62e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDvppvVQNMVQGKwrlGADF 86
Cdd:PRK08139  13 LLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHD----LKEMRAAR---GLAY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTL-NYVMATYS---KPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLF---PDVGASYFLSRLPGF 159
Cdd:PRK08139  86 FRALFARcSRVMQAIValpQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRNVPRKQAM 165
                        170       180       190
                 ....*....|....*....|....*....|....
gi 42569479  160 fgEYVgLTGARLDGAELLACGLATHFVPSTRLTA 193
Cdd:PRK08139 166 --EML-LTGEFIDAATAREWGLVNRVVPADALDA 196
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
4-158 1.17e-18

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 84.43  E-value: 1.17e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    4 QSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKwrlg 83
Cdd:PRK09674   1 MSELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMAEKDLAAT---- 76
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42569479   84 ADFFRDQYTLNyvMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG 158
Cdd:PRK09674  77 LNDPRPQLWQR--LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVG 149
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
5-228 1.85e-18

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 83.98  E-value: 1.85e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    5 SQVLVEEKSSVRILTLNRPKqLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDV---PPVVQnmvqgkwR 81
Cdd:PRK06495   4 SQLKLEVSDHVAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLkgrPDVIK-------G 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   82 LGADFFRDQYT--LNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLfpdVGASYFLSRL-PG 158
Cdd:PRK06495  76 PGDLRAHNRRTreCFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLfGH 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42569479  159 FFGEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCK-VGSSDPSFVSTILDAYTQHPHLKQKSAY 228
Cdd:PRK06495 153 SLTRRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAReIASKSPLATRLAKDALNTIENMSLRDGY 223
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
1-181 1.28e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 81.94  E-value: 1.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQ-GK 79
Cdd:PRK06142   2 MTTYESFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQlGK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   80 WRLG--ADFFRD-----QYTLNYVmATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGAsyf 152
Cdd:PRK06142  82 DGLArpRTDLRReilrlQAAINAV-ADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGS--- 157
                        170       180       190
                 ....*....|....*....|....*....|...
gi 42569479  153 LSRLPGFFGEYV----GLTGARLDGAELLACGL 181
Cdd:PRK06142 158 LQRLPRIIGDGHlrelALTGRDIDAAEAEKIGL 190
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
7-195 1.91e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 81.08  E-value: 1.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDV-----PPVVQNMVQGKWR 81
Cdd:PRK07509   5 VSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVksvasSPGNAVKLLFKRL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   82 LG-ADFFRdqytlnYVMATYSK---PQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLp 157
Cdd:PRK07509  85 PGnANLAQ------RVSLGWRRlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGL- 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 42569479  158 gffgeyVG--------LTGARLDGAELLACGLATHFVPSTRLTALE 195
Cdd:PRK07509 158 ------VRkdvareltYTARVFSAEEALELGLVTHVSDDPLAAALA 197
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
18-231 3.40e-17

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 80.51  E-value: 3.40e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   18 LTLNRPKQlnalcfNMI----SRLL-QLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQ-NMVQGKWRLGAdF---- 86
Cdd:PRK03580  16 ITLDRPKA------NAIdaktSFAMgEVFLNFRDDPELRVAIITGAGeKFFSAGWDLKAAAEgEAPDADFGPGG-Faglt 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 -FRDqytLNyvmatysKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFL-SRLPGFFGEYV 164
Cdd:PRK03580  89 eIFD---LD-------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLpKRLPPAIANEM 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42569479  165 GLTGARLDGAELLACGLATHFVPSTRLTALETDLCK-VGSSDPSFVSTILDAYTQHPHLKQKSAYHRL 231
Cdd:PRK03580 159 VMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQqLVNSAPLAIAALKEIYRETSEMPVEEAYRYI 226
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
7-155 4.27e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 80.08  E-value: 4.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSvKLVILKGQGRAFCAGGDVPPVVQNMVQGKwrlgadF 86
Cdd:PRK07659   8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSA-HIVVLRGNGRGFSAGGDIKMMLSSNDESK------F 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42569479   87 FRDQYTLN-YVMATYSKPQVSIlnGIVMGAGAG----VSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSR 155
Cdd:PRK07659  81 DGVMNTISeIVVTLYTMPKLTI--SAIHGPAAGlglsIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK 152
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-198 1.87e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 78.22  E-value: 1.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVppvvQNMVQGKw 80
Cdd:PRK07799   1 MEGGPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDL----KAATKKP- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 rlGADFFRD-QYTLNYVMATY-----SKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLS 154
Cdd:PRK07799  76 --PGDSFKDgSYDPSRIDALLkgrrlTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLV 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 42569479  155 R-LPGFFGEYVGLTGARLDGAELLACGLATHFVPSTrlTALETDL 198
Cdd:PRK07799 154 RqIPYTVACDLLLTGRHITAAEAKEIGLIGHVVPDG--QALDKAL 196
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
7-199 2.26e-16

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 78.51  E-value: 2.26e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDV----------PPVVQNMV 76
Cdd:PRK09120  10 VKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLkeyfretdaqPEILQERI 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   77 QgkwrlgadffRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRL 156
Cdd:PRK09120  90 R----------REAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADT 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 42569479  157 PGFFGE-YVGLTGARLDGAELLACGLATHFVPSTRLTALETDLC 199
Cdd:PRK09120 160 VGHRDAlYYIMTGETFTGRKAAEMGLVNESVPLAQLRARTRELA 203
PLN02600 PLN02600
enoyl-CoA hydratase
13-195 2.50e-16

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 77.92  E-value: 2.50e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   13 SSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQ-GRAFCAGGDVPpVVQNMVQGKWRLGADFFRDQY 91
Cdd:PLN02600   3 SGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSvPGVFCAGADLK-ERRKMSPSEVQKFVNSLRSTF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   92 TLnyvMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASyflSRLPGFFGEYVG----LT 167
Cdd:PLN02600  82 SS---LEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGT---QRLPRLVGRSRAkeliFT 155
                        170       180       190
                 ....*....|....*....|....*....|
gi 42569479  168 GARLDGAELLACGLATHFVPS--TRLTALE 195
Cdd:PLN02600 156 GRRIGAREAASMGLVNYCVPAgeAYEKALE 185
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
12-183 3.58e-16

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 77.63  E-value: 3.58e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   12 KSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPV----VQNMVQGKWRLGADFF 87
Cdd:PLN02664  15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLnsisEQSSSGDRGRSGERLR 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   88 RDQYTLNYVMATYS---KPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGAsyfLSRLPGFFG--- 161
Cdd:PLN02664  95 RKIKFLQDAITAIEqcrKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGygn 171
                        170       180
                 ....*....|....*....|...
gi 42569479  162 -EYVGLTGARLDGAELLACGLAT 183
Cdd:PLN02664 172 aMELALTGRRFSGSEAKELGLVS 194
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
7-191 4.87e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 77.09  E-value: 4.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVP----PVVQNMVQGKWRL 82
Cdd:PRK07260   4 IIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVemkrAVDEDDVQSLVKI 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   83 gADFFRDqytLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFF-G 161
Cdd:PRK07260  84 -AELVNE---ISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNrA 159
                        170       180       190
                 ....*....|....*....|....*....|
gi 42569479  162 EYVGLTGARLDGAELLACGLATHFVPSTRL 191
Cdd:PRK07260 160 THLAMTGEALTAEKALEYGFVYRVAESEKL 189
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
7-193 7.06e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 77.30  E-value: 7.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQN-----MVQGKWR 81
Cdd:PRK12478   7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGGGFQHwgeamMTDGRWD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   82 LGADFF----RDQYTLNYVMATY--SKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSL-GLFPdvgASYFLS 154
Cdd:PRK12478  87 PGKDFAmvtaRETGPTQKFMAIWraSKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYL---TGMWLY 163
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 42569479  155 RLPGFFGEYVGLTGARLDGAELLACGLATHFVPSTRLTA 193
Cdd:PRK12478 164 RLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEA 202
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-159 1.03e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 76.11  E-value: 1.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSqVLVEEKSSVRILTLNRPKQLNALCFNMiSRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKW 80
Cdd:PRK08140   1 MMYET-ILLAIEAGVATLTLNRPDKLNSFTREM-HRELREALDQVEDDGARALLLTGAGRGFCAGQDLADRDVTPGGAMP 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 42569479   81 RLGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF 159
Cdd:PRK08140  79 DLGESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGM 157
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
1-206 1.65e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 75.80  E-value: 1.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVPPVVQnmvqgk 79
Cdd:PRK06144   4 TTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGdKAFVAGTDIAQFRA------ 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   80 WRLGADFFRDQYTLNYVMA---TYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMP-ETSLGlfpDVGASYFLSR 155
Cdd:PRK06144  78 FSTAEDAVAYERRIDRVLGaleQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPiARTLG---NCLSMSNLAR 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 42569479  156 LPGFFG----EYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLC-KVGSSDP 206
Cdd:PRK06144 155 LVALLGaarvKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAeLLAAHAP 210
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
7-196 1.34e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 73.33  E-value: 1.34e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEE-KSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGD-----VPPVVQNMVQGKW 80
Cdd:PRK05864  11 VLVDHpRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADhksagVVPHVEGLTRPTY 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLgadffRDQYTLNYVMATYSK---PQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLF-PDVGASYFLSRL 156
Cdd:PRK05864  91 AL-----RSMELLDDVILALRRlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLSYLLPRA 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 42569479  157 PGFFGEY-VGLTGARLDGAELLACGLATHFVPSTRLtaLET 196
Cdd:PRK05864 166 IGSSRAFeIMLTGRDVDAEEAERIGLVSRQVPDEQL--LDT 204
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
7-187 3.85e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 71.59  E-value: 3.85e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDpsVKLVILKGQGRAFCAGGDvppvvqnMVQGKWRLGADF 86
Cdd:PRK08150   4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDHFCAGLD-------LSELRERDAGEG 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTLNYV---MATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF--FG 161
Cdd:PRK08150  75 MHHSRRWHRVfdkIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVarMT 154
                        170       180
                 ....*....|....*....|....*.
gi 42569479  162 EYVgLTGARLDGAELLACGLATHFVP 187
Cdd:PRK08150 155 DMM-LTGRVYDAQEGERLGLAQYLVP 179
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
5-207 1.23e-13

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 70.15  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    5 SQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPS-VKLVILKGQGRAFCAGGDVP--PVVQNMVQGKWR 81
Cdd:PRK05981   4 KKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAGRGFCTGANLQgrGSGGRESDSGGD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   82 LGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG-FF 160
Cdd:PRK05981  84 AGAALETAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGkAR 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 42569479  161 GEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDLCKVGSSDPS 207
Cdd:PRK05981 164 AMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPT 210
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
18-124 1.33e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 70.05  E-value: 1.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   18 LTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVpPVVQNMVqGKWRLGADFFRDQYTLNYVM 97
Cdd:PRK07327  25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDL-ALVEEMA-DDFEVRARVWREARDLVYNV 102
                         90       100       110
                 ....*....|....*....|....*....|...
gi 42569479   98 ATYSKPQVSILNGIVMGAG------AGVSIHGR 124
Cdd:PRK07327 103 INCDKPIVSAIHGPAVGAGlvaallADISIAAK 135
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
18-200 2.37e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.50  E-value: 2.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    18 LTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDvppvvqNMVQGKWrlGADFFRDQYTLNY- 95
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGdKAFCSGGD------QKVRGDY--GYIDDSGVHRLNVl 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    96 ----VMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG-FFGEYVGLTGAR 170
Cdd:TIGR01929  88 dvqrQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGqKKAREIWFLCRQ 167
                         170       180       190
                  ....*....|....*....|....*....|
gi 42569479   171 LDGAELLACGLATHFVPSTRLTALETDLCK 200
Cdd:TIGR01929 168 YDAKQALDMGLVNTVVPLADLEKETVRWCR 197
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
7-183 4.64e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 68.56  E-value: 4.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDV------PPVVQNMVQGKW 80
Cdd:PRK07827   8 VRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLseagggGGDPYDAAVARA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLGADFFRDQYTLnyvmatySKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRL-PGF 159
Cdd:PRK07827  88 REMTALLRAIVEL-------PKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLsPRA 160
                        170       180
                 ....*....|....*....|....
gi 42569479  160 FGEYVgLTGARLDGAELLACGLAT 183
Cdd:PRK07827 161 AARYY-LTGEKFGAAEAARIGLVT 183
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
18-193 6.10e-13

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 68.30  E-value: 6.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   18 LTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVpPVVQNMVQGKWRLGADFFRDQYTLNYVM 97
Cdd:PRK05674  19 LWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADL-AWMQQSADLDYNTNLDDARELAELMYNL 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   98 ATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAELL 177
Cdd:PRK05674  98 YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRRAR 177
                        170
                 ....*....|....*.
gi 42569479  178 ACGLATHFVPSTRLTA 193
Cdd:PRK05674 178 ELGLLAESYPAAELEA 193
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
7-158 7.09e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 67.89  E-value: 7.09e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSS---VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLG 83
Cdd:PRK06023   5 ILVERPGAhpgVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDFLAAAMGGTSFGS 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42569479   84 A--DFFrdqytlnYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG 158
Cdd:PRK06023  85 EilDFL-------IALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMG 154
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
7-188 2.67e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 66.14  E-value: 2.67e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLGADf 86
Cdd:PRK06563   1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVAPKLAAGGFPFPEG- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTLnyVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGfFGE---Y 163
Cdd:PRK06563  80 GIDPWGT--VGRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAG-WGNamrY 156
                        170       180
                 ....*....|....*....|....*
gi 42569479  164 VgLTGARLDGAELLACGLATHFVPS 188
Cdd:PRK06563 157 L-LTGDEFDAQEALRLGLVQEVVPP 180
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
3-194 6.76e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 65.06  E-value: 6.76e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    3 SQSQVLVEEKSSVRiLTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDVppvvQNMVQGKwR 81
Cdd:PRK06143   6 AHAGVTRDDRGVAT-LTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGeKAFIGGADI----KEMATLD-Q 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   82 LGADFF----RDqytLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLfPDVGASYFLSRLP 157
Cdd:PRK06143  80 ASAEAFisrlRD---LCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLI 155
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 42569479  158 GFF-GEYVGLTGARLDGAELLACGLATHFVPSTRLTAL 194
Cdd:PRK06143 156 GWArTRWLLLTGETIDAAQALAWGLVDRVVPLAELDAA 193
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
7-198 6.84e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 61.93  E-value: 6.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQN---MVQGKWRLG 83
Cdd:PRK08252   5 VLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFARGerpSIPGRGFGG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   84 adffrdqytlnYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFL-SRLPGFFGE 162
Cdd:PRK08252  85 -----------LTERPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLpRRIPYHIAM 153
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 42569479  163 YVGLTGARLDGAELLACGLATHFVPSTrlTALETDL 198
Cdd:PRK08252 154 ELALTGDMLTAERAHELGLVNRLTEPG--QALDAAL 187
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
15-182 9.16e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 61.58  E-value: 9.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   15 VRILTLNRPKQLNALCFNMISRLLQLFRAYEEDpSVKLVILKGQGRAFCAGGDvppvvqnmvqgkwrLGADFFRDQYT-- 92
Cdd:PRK07854  10 VLTIELQRPERRNALNAELCEELREAVRKAVDE-SARAIVLTGQGTVFCAGAD--------------LSGDVYADDFPda 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   93 ---LNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDvgaSYFLSRLpgffGEYVG---- 165
Cdd:PRK07854  75 lieMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRL----SSLVGggra 147
                        170       180
                 ....*....|....*....|.
gi 42569479  166 ----LTGARLDGAELLACGLA 182
Cdd:PRK07854 148 ramlLGAEKLTAEQALATGMA 168
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
6-193 3.26e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 60.36  E-value: 3.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    6 QVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGD---------VPPVVQNMV 76
Cdd:PRK08290   5 YVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDlgsgtpgrdRDPGPDQHP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   77 QGKW----RLGADFFRDQ---YTLNYVMATY--SKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLfpdV 147
Cdd:PRK08290  85 TLWWdgatKPGVEQRYAReweVYLGMCRRWRdlPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI---P 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 42569479  148 GASYFLSrlPGFFG-----EYVgLTGARLDGAELLACGLATHFVPSTRLTA 193
Cdd:PRK08290 162 GVEYFAH--PWELGprkakELL-FTGDRLTADEAHRLGMVNRVVPRDELEA 209
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
9-210 5.94e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 59.16  E-value: 5.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    9 VEEKSSVRILTLNRPKQlNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAF-CAGGDV-------PPVVQNMVQgkw 80
Cdd:PRK09076   7 LEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLnlfadgdKAVAREMAR--- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLGADF-----FRDqytlnyvmatyskpqVSI--LNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFL 153
Cdd:PRK09076  83 RFGEAFealsaFRG---------------VSIaaINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNL 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42569479  154 SRLpgffgeyVG--------LTGARLDGAELLACGLATHFVPstRLTALETDLC---KVGSSDPSFVS 210
Cdd:PRK09076 148 PWL-------VGegwakrmiLCGERVDAATALRIGLVEEVVE--KGEAREAALAlaqKVANQSPSAVA 206
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
15-195 1.45e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 58.06  E-value: 1.45e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   15 VRILTLNRPKqLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVP-----PVVQNMVqGKWRLGADFFRd 89
Cdd:PRK07938  12 IAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKelqatPGFTALI-DANRGCFAAFR- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   90 qytlnyvmATY--SKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLfpdVGASYFLSRL-PGFFGEYVGL 166
Cdd:PRK07938  89 --------AVYecAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGA---LGAATHLQRLvPQHLMRALFF 157
                        170       180       190
                 ....*....|....*....|....*....|.
gi 42569479  167 TGARLDGAELLACGLATHFVPSTRL--TALE 195
Cdd:PRK07938 158 TAATITAAELHHFGSVEEVVPRDQLdeAALE 188
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
3-198 3.31e-08

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 53.88  E-value: 3.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    3 SQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEdPSVKLVILkgqgRAFcAGGDVppvvqnmvqgkWRL 82
Cdd:PRK11423   2 SMQYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVIL----RAP-SGSKV-----------WSA 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   83 GADFF------RDqyTLNY---------VMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGL-FPD 146
Cdd:PRK11423  65 GHDIHelpsggRD--PLSYddplrqilrMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVpYNL 142
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 42569479  147 VGASYFLSRLPGFFGEYVGLTGARLDGAELLACGLATHFVPSTRLTALETDL 198
Cdd:PRK11423 143 SGILNFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQM 194
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-90 3.62e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 54.28  E-value: 3.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKW 80
Cdd:PRK08272   6 LDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSAYAEGSSSGGG 85
                         90
                 ....*....|
gi 42569479   81 RLGADFFRDQ 90
Cdd:PRK08272  86 GGAYPGKRQA 95
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
3-158 4.54e-08

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 54.84  E-value: 4.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479     3 SQSQVLVEEKSSVRILTLNRPK-QLNALCFNMISRLLQLFRAYEEDPSVK-LVILKGQGRAFCAGGDVPPV--------V 72
Cdd:TIGR02441  11 ARTHRHYEVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKsAVLISGKPGSFVAGADIQMIaacktaqeV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    73 QNMVQGKWRLgadFFRdqytlnyvMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATEN--TVFAMPETSLGLFPDVGAS 150
Cdd:TIGR02441  91 TQLSQEGQEM---FER--------IEKSQKPIVAAISGSCLGGGLELALACHYRIATKDrkTLLGLPEVMLGLLPGAGGT 159

                  ....*...
gi 42569479   151 YFLSRLPG 158
Cdd:TIGR02441 160 QRLPKLTG 167
PLN02921 PLN02921
naphthoate synthase
18-200 4.76e-08

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 54.02  E-value: 4.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   18 LTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDvppvvqNMVQGK-WRLGADFFRDQYTLNY 95
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGtKAFCSGGD------QAVRGKdGYVGPDDAGRLNVLDL 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   96 VMAT--YSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFpDVG-ASYFLSRLpgffgeyVGLTGAR-- 170
Cdd:PLN02921 154 QIQIrrLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARL-------VGQKKARem 225
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 42569479  171 ------LDGAELLACGLATHFVPstrLTALETDLCK 200
Cdd:PLN02921 226 wflarfYTASEALKMGLVNTVVP---LDELEGETVK 258
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
1-187 6.76e-08

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 53.05  E-value: 6.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    1 MASQSQVLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGdVPPVVQNMVQGKW 80
Cdd:PRK07110   1 MMMKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGG-TQEGLLSLQTGKG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 RLGADFFrdqYTLnyvMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPGF- 159
Cdd:PRK07110  80 TFTEANL---YSL---ALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLa 153
                        170       180
                 ....*....|....*....|....*...
gi 42569479  160 FGEYVGLTGARLDGAELLACGLATHFVP 187
Cdd:PRK07110 154 LGQEMLLTARYYRGAELKKRGVPFPVLP 181
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
7-189 1.14e-07

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 52.38  E-value: 1.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDpsVKLVILKGQGRAFCAGGDVPPVVQNMVQGKwrlgADF 86
Cdd:PRK07112   6 IRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGLPEVFCFGADFSAIAEKPDAGR----ADL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   87 FRDQYTLNYVMATYSKPQVSI--LNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPdvgASY--FLSRLPGFF-G 161
Cdd:PRK07112  80 IDAEPLYDLWHRLATGPYVTIahVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP---ACVlpFLIRRIGTQkA 156
                        170       180
                 ....*....|....*....|....*...
gi 42569479  162 EYVGLTGARLDGAELLACGLATHFVPST 189
Cdd:PRK07112 157 HYMTLMTQPVTAQQAFSWGLVDAYGANS 184
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
18-196 1.32e-07

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 52.20  E-value: 1.32e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   18 LTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG-RAFCAGGDvppvvQNM--------VQGKWRLGA-DFF 87
Cdd:PRK07396  26 ITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGdKAFCSGGD-----QKVrgyggyvdDDGVPRLNVlDLQ 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   88 RDqytlnyvMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFpD--VGASYfLSRLpgffgeyVG 165
Cdd:PRK07396 101 RL-------IRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSF-DggYGASY-LARI-------VG 164
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 42569479  166 LTGAR--------LDGAELLACGLATHFVPSTRLTAlET 196
Cdd:PRK07396 165 QKKAReiwflcrqYDAQEALDMGLVNTVVPLADLEK-ET 202
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
7-67 1.59e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 51.82  E-value: 1.59e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42569479    7 VLVEEKSSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGD 67
Cdd:PRK08259   5 VRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGAD 65
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
17-191 1.32e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 46.41  E-value: 1.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   17 ILTLNRpKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGR--AFCAGGDVPPVvqNMVQGKWRLGADFFRDQYTln 94
Cdd:PLN03214  24 VVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRrdVFTAGNDIAEL--YAPKTSAARYAEFWLTQTT-- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   95 YVMATYSKPQVSI--LNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGL-FPDVGASYFLSRLPG-FFGEYVGLTGAR 170
Cdd:PLN03214  99 FLVRLLRSRLATVcaIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDrKVAESLLLRGRL 178
                        170       180
                 ....*....|....*....|.
gi 42569479  171 LDGAELLACGLATHFVPSTRL 191
Cdd:PLN03214 179 VRPAEAKQLGLIDEVVPAAAL 199
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
43-158 1.58e-05

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 46.78  E-value: 1.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   43 AYEEDPSVKLVILKGQGRAFCAGGDVPPVVQNMVQGKWRLgadffrDQYtLNYVMATYSK------PQVSILNGIVMGAG 116
Cdd:PRK11730  45 ALEAQSDLKGLLLTSAKDAFIVGADITEFLSLFAAPEEEL------SQW-LHFANSIFNRledlpvPTVAAINGYALGGG 117
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 42569479  117 AGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG 158
Cdd:PRK11730 118 CECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
10-186 2.57e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 44.83  E-value: 2.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   10 EEKSSVRILTLNRPKQlNALCFNMISRLLQLFRAYEEDPSVKLVILKGQGRAFCAGGDVPPVvqNMVQGKWRLGADFFRD 89
Cdd:PRK05869  13 SQDAGLATLLLSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPEL--RTLSAQEADTAARVRQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   90 QYTlnYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATENTVFAMPETSLGLFPDVGASYFLSRLPG--------FFG 161
Cdd:PRK05869  90 QAV--DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGpsrakelvFSG 167
                        170       180
                 ....*....|....*....|....*
gi 42569479  162 EYVgltgarlDGAELLACGLATHFV 186
Cdd:PRK05869 168 RFF-------DAEEALALGLIDEMV 185
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
7-196 3.08e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 44.96  E-value: 3.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479    7 VLVEEKSSVRILTLNRPKqLNALCFNMISRLLQLFRAYEEDpsVKLVILKGQGRAFCAGGDVPPVVQ------NMVQGkw 80
Cdd:PRK06213   5 VSYTLEDGVATITLDDGK-VNALSPAMIDALNAALDQAEDD--RAVVVITGQPGIFSGGFDLKVMTSgaqaaiALLTA-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   81 rlGAdffrdqyTLNYVMATYSKPQVSILNG--IVMGA------GAGVSIHGRFRIatentvfAMPETSLGL-FPDVGASY 151
Cdd:PRK06213  80 --GS-------TLARRLLSHPKPVIVACTGhaIAKGAflllsaDYRIGVHGPFKI-------GLNEVAIGMtMPHAAIEL 143
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 42569479  152 FLSRL-PGFFGEYVGLtGARLDGAELLACGLATHFVPSTRL--TALET 196
Cdd:PRK06213 144 ARDRLtPSAFQRAVIN-AEMFDPEEAVAAGFLDEVVPPEQLlaRAQAA 190
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
15-195 4.50e-05

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 45.27  E-value: 4.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   15 VRILTLNRP-KQLNALCFNMISRLLQLFRAYEEDPSVK-LVILKGQGRAFCAGGDVppvvqNMVQG---------KWRLG 83
Cdd:PRK11154  16 IAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKgVVFISGKPDNFIAGADI-----NMLAAcktaqeaeaLARQG 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569479   84 ADFFRDqytlnyvMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATEN--TVFAMPETSLGLFPDVGASYFLSRLpgffg 161
Cdd:PRK11154  91 QQLFAE-------IEALPIPVVAAIHGACLGGGLELALACHYRVCTDDpkTVLGLPEVQLGLLPGSGGTQRLPRL----- 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 42569479  162 eyVG--------LTGARLDGAELLACGLATHFVPSTRL--TALE 195
Cdd:PRK11154 159 --IGvstaldmiLTGKQLRAKQALKLGLVDDVVPHSILleVAVE 200
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
15-67 5.28e-05

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 44.42  E-value: 5.28e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 42569479  15 VRIlTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQG------RAFCAGGD 67
Cdd:COG0447  29 ARI-AINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGpskdggWAFCSGGD 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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