NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|240254150|ref|NP_173858|]
View 

OxaA/YidC-like membrane insertion protein [Arabidopsis thaliana]

Protein Classification

YidC/Oxa1 family membrane protein insertase( domain architecture ID 10489205)

YidC/Oxa1 family membrane protein insertase functions as a membrane protein chaperone and as an independent insertase for membrane proteins

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
60KD_IMP pfam02096
60Kd inner membrane protein;
124-338 1.57e-70

60Kd inner membrane protein;


:

Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 222.73  E-value: 1.57e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  124 YGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPVW 203
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  204 IGLYRALSNVADEGlLTEGFFWIPSLAGPTTVAarqngSGISWLFPFIeghpplgwpdtlaylvlpllLVFSQYLSIQIM 283
Cdd:pfam02096  81 IALYRVLRNSIELR-HAPFFLWIADLSAPDPIS-----ILHYYILPIL--------------------MGVTMFLQQKLT 134

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 240254150  284 QSSQSNDPAMKssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQK 338
Cdd:pfam02096 135 PAPQDQPPQMK--MMMLYFMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
PTZ00121 super family cl31754
MAEBL; Provisional
 355-482 6.58e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 6.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  355 KEDKTQQIEKSFSEPLVQKSVSELKIPREKggEKVTPECPKPGERFRLLKEQEAKRRREkEERQKAEAALSNQNtDKAHE 434
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAE--EKKKAEELKKAEEENKIKAEEAKKEAE-EDKKKAEEAKKDEE-EKKKI 1759

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 240254150  435 QDEKSDTAIVAEDDKKTELSAVDETSDGTvavNGKPSIQKDETTNGTF 482
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEE---DEKRRMEVDKKIKDIF 1804
 
Name Accession Description Interval E-value
60KD_IMP pfam02096
60Kd inner membrane protein;
124-338 1.57e-70

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 222.73  E-value: 1.57e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  124 YGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPVW 203
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  204 IGLYRALSNVADEGlLTEGFFWIPSLAGPTTVAarqngSGISWLFPFIeghpplgwpdtlaylvlpllLVFSQYLSIQIM 283
Cdd:pfam02096  81 IALYRVLRNSIELR-HAPFFLWIADLSAPDPIS-----ILHYYILPIL--------------------MGVTMFLQQKLT 134

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 240254150  284 QSSQSNDPAMKssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQK 338
Cdd:pfam02096 135 PAPQDQPPQMK--MMMLYFMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
96-343 6.78e-70

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 221.92  E-value: 6.78e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  96 WFSGIANYMETILKVLKDGLStvhvpySYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQ 175
Cdd:COG0706    5 WFGFIAKPLFWLLNFLHSLVG------NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKLQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 176 LETARLYKLAGINPLAGCLPTLATIPVWIGLYRALSNVADegLLTEGFFWIPSLAGPttvaarqngSGISWLFPFIEGhp 255
Cdd:COG0706   79 QEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIE--LRHAPFLGIPDLSAP---------DPYYIFLPILMG-- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 256 plgwpdtlaylvlplllvFSQYLSiQIMQSSQSNDPAMKssqAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVW 335
Cdd:COG0706  146 ------------------VTMFLQ-QKLNPAPAQDPQQK---KMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLI 203


                 ....*...
gi 240254150 336 LQKYGGAK 343
Cdd:COG0706  204 INRRLDKK 211
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
 125-338 1.14e-64

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 207.23  E-value: 1.14e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 125 GFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPVWI 204
Cdd:cd20070    1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 205 GLYRALSNVADegLLTEGFFW-IPSLAGPTTVaarqngsgisWLFPFIeghpplgwpdtlaylvlpllLVFSQYLSIQIM 283
Cdd:cd20070   81 ALYQVLRNSIE--LRGAPFLWwILDLSAPDPY----------YILPIL--------------------MGVTMFLQQKLT 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 240254150 284 QssQSNDPAMKSSQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQK 338
Cdd:cd20070  129 P--TPTDDQAPQQKMMMYFMPVMFTFIFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
 123-336 1.21e-62

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 201.94  E-value: 1.21e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  123 SYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPV 202
Cdd:TIGR03592   1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  203 WIGLYRALSNVADegLLTEGFFWIPSLAGPttvaarqngsGISWLFPFIEGhpplgwpdtlaylvlplllvFSQYLSiQI 282
Cdd:TIGR03592  81 FIALYQVLLRSIE--LRHAPFLWIIDLSSP----------DPYYILPILMG--------------------VTMFLQ-QK 127

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 240254150  283 MQSSQSNDPAMKssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWL 336
Cdd:TIGR03592 128 LSPKGPPDPAQQ--KMMMYFMPLMFLFFFLSFPAGLVLYWVVSNLFTIIQQLII 179
PRK01318 PRK01318
membrane protein insertase; Provisional
 123-348 2.73e-48

membrane protein insertase; Provisional


Pssm-ID: 234942 [Multi-domain]  Cd Length: 521  Bit Score: 174.29  E-value: 2.73e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 123 SYGFAIILLTVLVKAATFPLTKKQVESaMA-MKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIP 201
Cdd:PRK01318 322 NWGWAIILLTIIVKLLLFPLTYKSYVS-MAkMKVLQPKMQELKEKYKDDPQKMQQEMMELYKKEKVNPLGGCLPILIQIP 400

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 202 VWIGLYRALsNVADEgLLTEGFF-WIP--SLAGPTTVAArqngsgISwLFPFIEGhpplgwpdtlaylvlplllvFSQYL 278
Cdd:PRK01318 401 IFFALYKVL-LVSIE-LRHAPFIgWIHdlSAPDPYFILH------IG-LLPILMG--------------------ITMFL 451

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 279 siQIMQSSQSNDPAMkssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQKYGGAKNPVEK 348
Cdd:PRK01318 452 --QQKLNPTPTDPMQ---AKIMKFMPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLINRRLEKKKLLAA 516
PTZ00121 PTZ00121
MAEBL; Provisional
 355-482 6.58e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 6.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  355 KEDKTQQIEKSFSEPLVQKSVSELKIPREKggEKVTPECPKPGERFRLLKEQEAKRRREkEERQKAEAALSNQNtDKAHE 434
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAE--EKKKAEELKKAEEENKIKAEEAKKEAE-EDKKKAEEAKKDEE-EKKKI 1759

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 240254150  435 QDEKSDTAIVAEDDKKTELSAVDETSDGTvavNGKPSIQKDETTNGTF 482
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEE---DEKRRMEVDKKIKDIF 1804
 
Name Accession Description Interval E-value
60KD_IMP pfam02096
60Kd inner membrane protein;
124-338 1.57e-70

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 222.73  E-value: 1.57e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  124 YGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPVW 203
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  204 IGLYRALSNVADEGlLTEGFFWIPSLAGPTTVAarqngSGISWLFPFIeghpplgwpdtlaylvlpllLVFSQYLSIQIM 283
Cdd:pfam02096  81 IALYRVLRNSIELR-HAPFFLWIADLSAPDPIS-----ILHYYILPIL--------------------MGVTMFLQQKLT 134

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 240254150  284 QSSQSNDPAMKssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQK 338
Cdd:pfam02096 135 PAPQDQPPQMK--MMMLYFMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
96-343 6.78e-70

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 221.92  E-value: 6.78e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  96 WFSGIANYMETILKVLKDGLStvhvpySYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQ 175
Cdd:COG0706    5 WFGFIAKPLFWLLNFLHSLVG------NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKLQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 176 LETARLYKLAGINPLAGCLPTLATIPVWIGLYRALSNVADegLLTEGFFWIPSLAGPttvaarqngSGISWLFPFIEGhp 255
Cdd:COG0706   79 QEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIE--LRHAPFLGIPDLSAP---------DPYYIFLPILMG-- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 256 plgwpdtlaylvlplllvFSQYLSiQIMQSSQSNDPAMKssqAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVW 335
Cdd:COG0706  146 ------------------VTMFLQ-QKLNPAPAQDPQQK---KMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLI 203


                 ....*...
gi 240254150 336 LQKYGGAK 343
Cdd:COG0706  204 INRRLDKK 211
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
 125-338 1.14e-64

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 207.23  E-value: 1.14e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 125 GFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPVWI 204
Cdd:cd20070    1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 205 GLYRALSNVADegLLTEGFFW-IPSLAGPTTVaarqngsgisWLFPFIeghpplgwpdtlaylvlpllLVFSQYLSIQIM 283
Cdd:cd20070   81 ALYQVLRNSIE--LRGAPFLWwILDLSAPDPY----------YILPIL--------------------MGVTMFLQQKLT 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 240254150 284 QssQSNDPAMKSSQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQK 338
Cdd:cd20070  129 P--TPTDDQAPQQKMMMYFMPVMFTFIFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
 123-336 1.21e-62

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 201.94  E-value: 1.21e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  123 SYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPV 202
Cdd:TIGR03592   1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  203 WIGLYRALSNVADegLLTEGFFWIPSLAGPttvaarqngsGISWLFPFIEGhpplgwpdtlaylvlplllvFSQYLSiQI 282
Cdd:TIGR03592  81 FIALYQVLLRSIE--LRHAPFLWIIDLSSP----------DPYYILPILMG--------------------VTMFLQ-QK 127

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 240254150  283 MQSSQSNDPAMKssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWL 336
Cdd:TIGR03592 128 LSPKGPPDPAQQ--KMMMYFMPLMFLFFFLSFPAGLVLYWVVSNLFTIIQQLII 179
PRK01318 PRK01318
membrane protein insertase; Provisional
 123-348 2.73e-48

membrane protein insertase; Provisional


Pssm-ID: 234942 [Multi-domain]  Cd Length: 521  Bit Score: 174.29  E-value: 2.73e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 123 SYGFAIILLTVLVKAATFPLTKKQVESaMA-MKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIP 201
Cdd:PRK01318 322 NWGWAIILLTIIVKLLLFPLTYKSYVS-MAkMKVLQPKMQELKEKYKDDPQKMQQEMMELYKKEKVNPLGGCLPILIQIP 400

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 202 VWIGLYRALsNVADEgLLTEGFF-WIP--SLAGPTTVAArqngsgISwLFPFIEGhpplgwpdtlaylvlplllvFSQYL 278
Cdd:PRK01318 401 IFFALYKVL-LVSIE-LRHAPFIgWIHdlSAPDPYFILH------IG-LLPILMG--------------------ITMFL 451

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 279 siQIMQSSQSNDPAMkssQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQKYGGAKNPVEK 348
Cdd:PRK01318 452 --QQKLNPTPTDPMQ---AKIMKFMPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLINRRLEKKKLLAA 516
PRK00145 PRK00145
putative inner membrane protein translocase component YidC; Provisional
 97-348 2.03e-39

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234665 [Multi-domain]  Cd Length: 223  Bit Score: 142.57  E-value: 2.03e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  97 FSGIANYMETILKVLKDGLSTV--HVPYSYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKI 174
Cdd:PRK00145   2 MRYLNNAFVQFFKFIHGFVSSVisNPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKNDPQKL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 175 QLETARLYKLAGINPLAGCLPTLATIPVWIGLYRALSNVadEGLLTEGFFWIPSLAGPTtvaarqngsgISWLFPFIEGh 254
Cdd:PRK00145  82 QQEMMKLYKEKGVNPLGGCLPLLIQWPILIALYYVFNNL--TGINGVSFLWIKDLAKPD----------ITWILPILSG- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 255 pplgwpdtlaylvlplllvFSQYLSIQIMQSSQSNDPamKSSQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQV 334
Cdd:PRK00145 149 -------------------ATTYLSGYLMTKADSSQA--GQMKTMNIGMSIFMGVMSWKFKSALVLYWVIGNLIQIIQTY 207

                        250
                 ....*....|....
gi 240254150 335 WLQKYGGAKNPVEK 348
Cdd:PRK00145 208 FIKKLELKKKVEAK 221
PRK01622 PRK01622
membrane protein insertase YidC;
119-338 5.90e-32

membrane protein insertase YidC;


Pssm-ID: 179310  Cd Length: 256  Bit Score: 123.32  E-value: 5.90e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 119 HVPYSYGFAIILLTVLVKAATFPLT----KKQVESAMAMKSLTPQIKAIQERY--AGDQEK---IQLETARLYKLAGINP 189
Cdd:PRK01622  55 HIGGSYGIAIIIVTLIIRSLMIPLAvsqyKSQRGMQEKMAVMKPELDKIQAKLkvTKDLEKqkeYQKEMMELYKSGNINP 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 190 LA-GCLPTLATIPVWIGLYRALSNVadEGLLTEGFFWIpSLAGPttvaarqngsgiSWLFPFIEGhpplgwpdtlaylvl 268
Cdd:PRK01622 135 LAmGCLPLLIQMPILSAFYYAIRRT--EEIASHSFLWF-NLGHA------------DHILPIIAG--------------- 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 269 plllvFSQYLSIQIMQSSQSNDPAMKSSQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWLQK 338
Cdd:PRK01622 185 -----LTYFIQMKVSQSNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITGGLFLMGQTIVLRK 249
5TM_YidC_Oxa1_Alb3 cd19751
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ...
 125-333 1.23e-30

Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410992 [Multi-domain]  Cd Length: 189  Bit Score: 117.65  E-value: 1.23e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 125 GFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGD------QEKIQLETARLYKLAGINPLAGCLPTLA 198
Cdd:cd19751    1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKaskdkvQQEMQKEMLGLYKKHGVNPMAGCLPLFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 199 TIPVWIGLYRALSNVadEGLLTEGFFWIPSLAGPTTVaarqngsgisWLFPFIEGhpplgwpdtlaylvlpLLLVFSQYL 278
Cdd:cd19751   81 QLPIFMAFYFAIMRT--EEIRYHTFLWFFDLGQPDYL----------YILPFVAG----------------ITTYFQFKM 132

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 240254150 279 SIQIMQSSQSNDPAMKSsqaVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQ 333
Cdd:cd19751  133 TMSHQQQMQMMQMQMKV---MLYVMPVMIIIAGLSFPSALSLYWIISNLFMIIQT 184
PRK01315 PRK01315
putative inner membrane protein translocase component YidC; Provisional
 123-333 4.26e-29

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234941  Cd Length: 329  Bit Score: 117.15  E-value: 4.26e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 123 SYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPV 202
Cdd:PRK01315  41 TWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGDRERMSQEMMKLYKETGTNPLSSCLPLLLQMPI 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 203 WIGLYRALSNVADE----GLLTEG---------FFWIPsLAGpTTVAARQNGSGISWLFPFIeghpplgwpdtlAYLVLP 269
Cdd:PRK01315 121 FFALYRVLDSAASRgdgiGPINPPllesfrhahIFGAP-LAA-TFLQALNAGNTAVQVVAAV------------LIILMS 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240254150 270 LLLVFSQylsIQIMQSSQSND----PAMKSSQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQ 333
Cdd:PRK01315 187 ASQFITQ---LQLMTKNMPPEaktgPMAQQQKMLLYLFPLMFLVSGIAFPVGVLFYWLTSNVWTMGQQ 251
5TM_Oxa1-like cd20069
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ...
 127-336 6.36e-29

Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410993 [Multi-domain]  Cd Length: 201  Bit Score: 113.00  E-value: 6.36e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 127 AIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQE-----RYAGDQE---KIQLETARLYKLAGINPLAGCLPTLA 198
Cdd:cd20069    7 TIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEklkeaRASGDQLeaaEARKELKELMKKHNVNPLKSLLLPLV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 199 TIPVWIGLY---RALSNVADEGLLTEGFFWIPSL--AGPTtvaarqngsgisWLFPFIEGhpplgwpdtlaylvlplllv 273
Cdd:cd20069   87 QAPVFISFFfalRKMANLPVPSFKTGGLLWFTDLtvPDPY------------YILPILTS-------------------- 134

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 240254150 274 FSQYLSIQI----MQSSQSNDPAMKSsqaVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWL 336
Cdd:cd20069  135 LTFLATIELgaetGTSGSPQSKTMKN---VFRGLPVLMIPFTANFPSAVFLYWITSNLFSLAQNLLL 198
PRK02944 PRK02944
YidC family membrane integrase SpoIIIJ;
123-343 5.50e-28

YidC family membrane integrase SpoIIIJ;


Pssm-ID: 179508  Cd Length: 255  Bit Score: 112.17  E-value: 5.50e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 123 SYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERY----AGDQEKIQLETARLYKLAGINPLAGCLPTLA 198
Cdd:PRK02944  58 NYGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYsskdQATQQKLQQEMMQLFQKNGVNPLAGCLPIFI 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 199 TIPVWIGLYRAL---SNVADEGLL------TEGFFWIPSLAGPTTvaarqngsgiswlfpFIEghpplgwpdtlaylvlp 269
Cdd:PRK02944 138 QMPILIAFYHAImrtSEISKHSFLwfdlgqADPYYILPIVAGITT---------------FIQ----------------- 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 270 lllvfsQYLsiqIMQSSQSNDPAMKssqAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQ-------QVWLQKYGGA 342
Cdd:PRK02944 186 ------QKL---MMAGTAGQNPQMA---MMLWLMPIMILIFAINFPAALSLYWVVGNIFMIAQtylikgpEIKASKAGGS 253


                 .
gi 240254150 343 K 343
Cdd:PRK02944 254 K 254
PRK01001 PRK01001
putative inner membrane protein translocase component YidC; Provisional
 96-338 9.97e-24

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234887 [Multi-domain]  Cd Length: 795  Bit Score: 105.27  E-value: 9.97e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  96 WFSGI----ANYMETILKVLKdglstvHVPYSYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQ 171
Cdd:PRK01001 550 FFSFItepfAALLFIIMKFFK------FLTGSWGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKYKKEP 623

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 172 EKIQLETARLYKLAGINPLAGCLPTLATIPVWIGLYRALSNvadEGLLTEGFF---WIPSLAGPTTVaarqngsgISWLF 248
Cdd:PRK01001 624 KRAQMEIMALYKTNKVNPITGCLPLLIQLPFLIAMFDLLKS---SFLLRGASFipgWIDNLTAPDVL--------FSWET 692

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 249 P--FI--EGH--PPLgwpdtlaylvlPLLLVFSQylsiQIMQSSQSNDPA---MKSSQAVTKLLPLMIGYFALSVPSGLS 319
Cdd:PRK01001 693 PiwFIgnEFHllPIL-----------LGVVMFAQ----QKISSLKRKGPVtdqQRQQEAMGTMMALLFTFMFYNFPSGLN 757

                        250
                 ....*....|....*....
gi 240254150 320 LYWLTNNILSTAQQVWLQK 338
Cdd:PRK01001 758 IYWLSSMLLGVIQQWVTNK 776
PRK03449 PRK03449
putative inner membrane protein translocase component YidC; Provisional
 127-336 1.25e-23

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 179580  Cd Length: 304  Bit Score: 100.91  E-value: 1.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 127 AIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGDQEKIQLETARLYKLAGINPLAGCLPTLATIPVWIGL 206
Cdd:PRK03449  35 SVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGNDRQKMALEMQKLQKEHGFNPILGCLPMLAQIPVFLGL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 207 YRAL-------SNVADEGLLTEGFFWIPS-LAGPTTVA----ARQNGSGISwlfPFIEgHPPLGWPDTLAYLVLPLLLV- 273
Cdd:PRK03449 115 FHVLrsfnrtgTGFGQLGMSVEENRNTPNyVFSAEDVQsfldARLFGAPLS---AYIT-MPRSGLDAFVDFTRTNIILVg 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 240254150 274 ------------FSQYLSIQIMQSSQSNDP--AMKSSQAVTkLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVWL 336
Cdd:PRK03449 191 vplmiiagvathFNSRASVARQSAEAAANPqtAMMNKLALW-VFPLGVLVGGPFLPLAILLYWVSNNIWTFGQQHYV 266
PRK02654 PRK02654
putative inner membrane protein translocase component YidC; Provisional
 120-210 1.54e-19

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 235058  Cd Length: 375  Bit Score: 90.04  E-value: 1.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 120 VPySYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKA----IQERYAGDQEKIQLETARLYKLAGiNPLAGCLP 195
Cdd:PRK02654  24 VP-SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYKNDPQKQQEEMGKLMKEFG-NPLAGCLP 101

                         90
                 ....*....|....*
gi 240254150 196 TLATIPVWIGLYRAL 210
Cdd:PRK02654 102 LLVQMPILFALFATL 116
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
 123-480 5.57e-17

putative inner membrane protein translocase component YidC; Validated


Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 82.98  E-value: 5.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 123 SYGFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAG--DQEKIQLETAR---LYKLAGINPLAGCLPTL 197
Cdd:PRK00247  31 AWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGktDEASIRELQQKqkdLNKEYGYNPLAGCVPAL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 198 ATIPVWIGLYRALSNVA--DEGL-------------------LTEGFFWIPsLAGPTTVAARQ---NGSGISWLFPFIEg 253
Cdd:PRK00247 111 IQIPVFLGLYQVLLRMArpEGGLenpvhqpigfltseevesfLQGRVFNVP-LPAYVSMPAEQlayLGTTQATVLAFVL- 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 254 hpPLgwpdtlaylvLPLLLVFSQY-LSIQIMQSSQSNDPAMKSSQAVTKLL----------PLMIGYFAlSVPSGLSLYW 322
Cdd:PRK00247 189 --PL----------FIAAAVFTAInMAMSTYRSFQTNDHDSGFAVGMLKFLivmailapifPLSLGLTG-PFPTAIALYW 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 323 LTNNILSTAQQVWLQKYGGAKNPvekftnlVTKEDKTQQIEK--SFSEPLVQKSVSELKIPREKGGEKVTP--------- 391
Cdd:PRK00247 256 VANNLWTLIQNIIMYLILERKYP-------LTDEFKEHHAEQraQYREKQKEKKAFLWTLRRNRLRMIITPwrapelhae 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 392 --ECPKpgERFRLLKEQEAKRRREKEERQKAEAALSNQNTDKAHEQDEKSDTAIVAEDDKKTELSAVDETSDGTVAV--- 466
Cdd:PRK00247 329 naEIKK--TRTAEKNEAKARKKEIAQKRRAAEREINREARQERAAAMARARARRAAVKAKKKGLIDASPNEDTPSENees 406

                        410
                 ....*....|....
gi 240254150 467 NGKPSIQKDETTNG 480
Cdd:PRK00247 407 KGSPPQVEATTTAE 420
PRK02463 PRK02463
OxaA-like protein precursor; Provisional
 124-418 2.04e-16

OxaA-like protein precursor; Provisional


Pssm-ID: 235040  Cd Length: 307  Bit Score: 79.77  E-value: 2.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 124 YGFAIILLTVLVKAATFPLTKKQVESAM----AMKSLTPQIKAIQERY--AGDQ-EKIQLETARL--YKLAGINPLA--G 192
Cdd:PRK02463  60 FGLAIIIVTIIVRLIILPLGLYQSWKATyqseKMAYLKPVFEPINERLknATTQeEKMAAQTELMaaQRENGISMLGgiG 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 193 CLPTLATIPVWIGLYRALSNVadEGLLTEGFFWIpslagpttvaarqngsgiswlfpfieghpPLGWPDTLAYLVLPLLL 272
Cdd:PRK02463 140 CLPLLIQMPFFSALYFAAQYT--KGVSTSTFLGI-----------------------------DLGSPSLVLTAIIGVLY 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 273 VFSQYLSIQIMQSSQSndpamKSSQAVTKLLPLMIGYFALSVPSGLSLYWLTNNILSTAQQVwlqkyggaknpvekFTNL 352
Cdd:PRK02463 189 FFQSWLSMMGVPEEQR-----EQMKAMMYMMPIMMVVFSFSSPAGVGLYWLVGGFFSIIQQL--------------ITTY 249

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240254150 353 VTKEDKTQQIEKSFSE--PLVQKSVSELKiprekggeKVTPEcpKPGERFRLLKEQEAKRRREKEERQ 418
Cdd:PRK02463 250 ILKPRLRKQIAEEFAKnpPKAYKSPSGRK--------DVTPS--QNQAIASLPKKKKKNRNAGKQRKR 307
PRK02201 PRK02201
putative inner membrane protein translocase component YidC; Provisional
 100-348 2.79e-11

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 235012  Cd Length: 357  Bit Score: 65.03  E-value: 2.79e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 100 IANYMETILKVLKDGLSTVhvpysygFAIILLTVLVKAATFPLTKKQVESAMAMKSLTPQIKAIQERYAGD------QEK 173
Cdd:PRK02201 116 ILSIMASQSLSELYGWSTI-------LAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDYkkdkqmKQR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 174 IQLETARLYKLAGINPLAGCLPTLATIPVWIGLYRALSNvadeglltegffwIPSLagpttvaarqngSGISWL-FPFIE 252
Cdd:PRK02201 189 KQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQS-------------LPSI------------KVTTWLgIDLSA 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150 253 GhpPL------GWPDTLAYLVLPLLLVFSQYLSiQIMQS--------SQSNDPAMKSSQAVTKLLPLMIGYFALSVPSGL 318
Cdd:PRK02201 244 T--SWqeifagNWIYLPILIIVVPVQALSQLLP-QILNKkknkertlNVKEKEALKKQNKTQNIISIVFIFFGVIFAAGV 320

                        250       260       270
                 ....*....|....*....|....*....|
gi 240254150 319 SLYWLTNNILSTAQQVWLQKYGGAKNPVEK 348
Cdd:PRK02201 321 QIYWIIGGIWTILQTLGIHYFKKRKFYKQK 350
PTZ00121 PTZ00121
MAEBL; Provisional
 355-482 6.58e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 6.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240254150  355 KEDKTQQIEKSFSEPLVQKSVSELKIPREKggEKVTPECPKPGERFRLLKEQEAKRRREkEERQKAEAALSNQNtDKAHE 434
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAE--EKKKAEELKKAEEENKIKAEEAKKEAE-EDKKKAEEAKKDEE-EKKKI 1759

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 240254150  435 QDEKSDTAIVAEDDKKTELSAVDETSDGTvavNGKPSIQKDETTNGTF 482
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEE---DEKRRMEVDKKIKDIF 1804
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH