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Conserved domains on  [gi|15147221|ref|NP_150240|]
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galanin peptides preproprotein [Rattus norvegicus]

Protein Classification

Galanin domain-containing protein( domain architecture ID 12188513)

Galanin domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Galanin smart00071
Galanin; Galanin is a neuropeptide that controls various biological activities: it regulates ...
 21-124 7.39e-64

Galanin; Galanin is a neuropeptide that controls various biological activities: it regulates the release growth hormone, inhibits the release of insulin and somatostatin, contracts smooth muscle of the gastrointestinal and genitourinary tract and may be involved in the control of adrenal secretion


:

Pssm-ID: 128385 [Multi-domain]  Cd Length: 103  Bit Score: 189.32  E-value: 7.39e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15147221     21 TLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVeEGRLGSVAVPLPESNIVRTIMEFLSFLHL 100
Cdd:smart00071   1 TLGLGSPVKEKRGWTLNSAGYLLGPHAIDNHRSFHDKHGLTGKRELEPED-EARPGSFDRPLSESNIVRTIIEFLTFLHL 79

                           90       100
                   ....*....|....*....|....
gi 15147221    101 KEAGALDSLPGIPLATSSEDLEQS 124
Cdd:smart00071  80 KEAGALDRLPDLPSAASSEDAEQS 103
 
Name Accession Description Interval E-value
Galanin smart00071
Galanin; Galanin is a neuropeptide that controls various biological activities: it regulates ...
 21-124 7.39e-64

Galanin; Galanin is a neuropeptide that controls various biological activities: it regulates the release growth hormone, inhibits the release of insulin and somatostatin, contracts smooth muscle of the gastrointestinal and genitourinary tract and may be involved in the control of adrenal secretion


Pssm-ID: 128385 [Multi-domain]  Cd Length: 103  Bit Score: 189.32  E-value: 7.39e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15147221     21 TLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVeEGRLGSVAVPLPESNIVRTIMEFLSFLHL 100
Cdd:smart00071   1 TLGLGSPVKEKRGWTLNSAGYLLGPHAIDNHRSFHDKHGLTGKRELEPED-EARPGSFDRPLSESNIVRTIIEFLTFLHL 79

                           90       100
                   ....*....|....*....|....
gi 15147221    101 KEAGALDSLPGIPLATSSEDLEQS 124
Cdd:smart00071  80 KEAGALDRLPDLPSAASSEDAEQS 103
GMAP pfam06540
Galanin message associated peptide (GMAP); This family consists of several galanin message ...
 62-123 9.57e-32

Galanin message associated peptide (GMAP); This family consists of several galanin message associated peptides. In rat preprogalanin, galanin is C-terminally flanked by a 60 amino acid long peptide: galanin message-associated peptide (GMAP). GMAP sequences in different species show high degree of homology, but the biological function of this family is unknown.


Pssm-ID: 461941  Cd Length: 61  Bit Score: 106.76  E-value: 9.57e-32
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15147221    62 GKRELPLEvEEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQ 123
Cdd:pfam06540   1 GKRELQPE-DEAKPGSFDRPLPENNIVRTIIEFLTFLHLKEAGALDNLPDLPPAVSSEDTEQ 61
 
Name Accession Description Interval E-value
Galanin smart00071
Galanin; Galanin is a neuropeptide that controls various biological activities: it regulates ...
 21-124 7.39e-64

Galanin; Galanin is a neuropeptide that controls various biological activities: it regulates the release growth hormone, inhibits the release of insulin and somatostatin, contracts smooth muscle of the gastrointestinal and genitourinary tract and may be involved in the control of adrenal secretion


Pssm-ID: 128385 [Multi-domain]  Cd Length: 103  Bit Score: 189.32  E-value: 7.39e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15147221     21 TLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVeEGRLGSVAVPLPESNIVRTIMEFLSFLHL 100
Cdd:smart00071   1 TLGLGSPVKEKRGWTLNSAGYLLGPHAIDNHRSFHDKHGLTGKRELEPED-EARPGSFDRPLSESNIVRTIIEFLTFLHL 79

                           90       100
                   ....*....|....*....|....
gi 15147221    101 KEAGALDSLPGIPLATSSEDLEQS 124
Cdd:smart00071  80 KEAGALDRLPDLPSAASSEDAEQS 103
GMAP pfam06540
Galanin message associated peptide (GMAP); This family consists of several galanin message ...
 62-123 9.57e-32

Galanin message associated peptide (GMAP); This family consists of several galanin message associated peptides. In rat preprogalanin, galanin is C-terminally flanked by a 60 amino acid long peptide: galanin message-associated peptide (GMAP). GMAP sequences in different species show high degree of homology, but the biological function of this family is unknown.


Pssm-ID: 461941  Cd Length: 61  Bit Score: 106.76  E-value: 9.57e-32
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15147221    62 GKRELPLEvEEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQ 123
Cdd:pfam06540   1 GKRELQPE-DEAKPGSFDRPLPENNIVRTIIEFLTFLHLKEAGALDNLPDLPPAVSSEDTEQ 61
Galanin pfam01296
Galanin;
33-60 1.83e-13

Galanin;


Pssm-ID: 366564  Cd Length: 29  Bit Score: 59.56  E-value: 1.83e-13
                          10        20
                  ....*....|....*....|....*...
gi 15147221    33 GWTLNSAGYLLGPHAIDNHRSFSDKHGL 60
Cdd:pfam01296   1 GWTLNSAGYLLGPHAIDGHRSFGDKHGL 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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