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Conserved domains on  [gi|50083293|ref|NP_116205|]
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centrosomal protein of 89 kDa [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 421-767 1.21e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 1.21e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 421 EEWRQLQTQAKLV-LEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQE 499
Cdd:COG1196 213 ERYRELKEELKELeAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 500 LKTHsdgKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRK 579
Cdd:COG1196 293 LLAE---LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 580 SQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGyKK 659
Cdd:COG1196 370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE-AA 448

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 660 QAALKLGDISHRLLEQQEDFAGKTAQYRQEMRHLHQVLKDKQEVLDQALQQNREMEGELEVIWEStfRENRRIRELLQDT 739
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA--LLLAGLRGLAGAV 526

                       330       340
                ....*....|....*....|....*...
gi 50083293 740 LTRTGVQDNPRALVAPSLNGVSQADLLD 767
Cdd:COG1196 527 AVLIGVEAAYEAALEAALAAALQNIVVE 554
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 260-496 2.69e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 2.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 260 ELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAApellyLRKQAQELVDENDGLKMTVHRLNVELSRYQTKFRHL 339
Cdd:COG4942  28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA-----LARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 340 SKEESLNIEGLPSKGPIPPWLLdikylsplLLAYEDMmkekdelnatlkEEMRMFRMRVQEVVKENEELHQELNKssavT 419
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLAL--------LLSPEDF------------LDAVRRLQYLKYLAPARREQAEELRA----D 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50083293 420 SEEWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAkthgQEKELAENREQLEILRAK 496
Cdd:COG4942 159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA----ELAELQQEAEELEALIAR 231
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 421-767 1.21e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 1.21e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 421 EEWRQLQTQAKLV-LEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQE 499
Cdd:COG1196 213 ERYRELKEELKELeAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 500 LKTHsdgKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRK 579
Cdd:COG1196 293 LLAE---LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 580 SQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGyKK 659
Cdd:COG1196 370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE-AA 448

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 660 QAALKLGDISHRLLEQQEDFAGKTAQYRQEMRHLHQVLKDKQEVLDQALQQNREMEGELEVIWEStfRENRRIRELLQDT 739
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA--LLLAGLRGLAGAV 526

                       330       340
                ....*....|....*....|....*...
gi 50083293 740 LTRTGVQDNPRALVAPSLNGVSQADLLD 767
Cdd:COG1196 527 AVLIGVEAAYEAALEAALAAALQNIVVE 554
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 238-714 4.24e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.57  E-value: 4.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   238 EKFEALKEEN----MDLNNMNQSLTLELNTMK----QAMKELQLKLKgmeKEKRKLKEAEKASSQEVAAPEllylrKQAQ 309
Cdd:pfam05483 172 KKYEYEREETrqvyMDLNNNIEKMILAFEELRvqaeNARLEMHFKLK---EDHEKIQHLEEEYKKEINDKE-----KQVS 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   310 ELVDENDGLKMTVHRLNVELSRYQTKFRHLSKEESLNIEGLPS----KGPIPPWLLDIKYlsplllayedMMKEKDELNA 385
Cdd:pfam05483 244 LLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKEliekKDHLTKELEDIKM----------SLQRSMSTQK 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   386 TLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQLQT------------QAKLVLEENKLLLEQLEIQQR---- 449
Cdd:pfam05483 314 ALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEAttcsleellrteQQRLEKNEDQLKIITMELQKKssel 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   450 ----KAKDSHQERLQEVSKL--TKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHsDGKIAVEVHKSI------- 516
Cdd:pfam05483 394 eemtKFKNNKEVELEELKKIlaEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIH-DLEIQLTAIKTSeehylke 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   517 VNELKSQLQKEEEkeraemeelmeKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMG 596
Cdd:pfam05483 473 VEDLKTELEKEKL-----------KNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   597 NEMsahQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQAALKLGDISHrlLEQQ 676
Cdd:pfam05483 542 KEM---NLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE--LHQE 616

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 50083293   677 EDFAGKTAQYRQEMRHLHQVLKDKQEV-LDQALQQNREM 714
Cdd:pfam05483 617 NKALKKKGSAENKQLNAYEIKVNKLELeLASAKQKFEEI 655
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 449-740 4.69e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 4.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    449 RKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRakcQELKTHSDGKIAVEVHKSIVNELKSQLQKEE 528
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE---EELEQLRKELEELSRQISALRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    529 EKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANL 608
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    609 VGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKgyKKQAALKLgdISHRLLEQQEDFAGKTAQYRQ 688
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEA--LLNERASLEEALALLRSELEE 898

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 50083293    689 EMRHLHQVLKDKQEvLDQALQQNREMEGELEVIWEST-FRENR---RIRELLQDTL 740
Cdd:TIGR02168  899 LSEELRELESKRSE-LRRELEELREKLAQLELRLEGLeVRIDNlqeRLSEEYSLTL 953
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
238-721 2.68e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 2.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  238 EKFEALKEENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASsqevaaPELLYLRKQAQELVDENDG 317
Cdd:PRK03918 231 KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL------KELKEKAEEYIKLSEFYEE 304

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  318 LKMTVHRLNVELSRYQTKF----RHLSKEESLNIEGLPSKGPIPPWLLDIKYLSPLLLAYEDMMKEKDELNATLKE---- 389
Cdd:PRK03918 305 YLDELREIEKRLSRLEEEIngieERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltgl 384

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  390 EMRMFRMRVQEVVKENEELHQELNKSSAVTSEeWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERL-----QEVSK 464
Cdd:PRK03918 385 TPEKLEKELEELEKAKEEIEEEISKITARIGE-LKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELleeytAELKR 463

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  465 LTKQLMLLEAKthgqEKELAENREQLEILRAKCQELKTHsdgKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTV 544
Cdd:PRK03918 464 IEKELKEIEEK----ERKLRKELRELEKVLKKESELIKL---KELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK 536

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  545 LQAQKKSLLLEKNSLTEQNKALEaELERaqKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGL------AENITQE 618
Cdd:PRK03918 537 LKGEIKSLKKELEKLEELKKKLA-ELEK--KLDELEEELAELLKELEELGFESVEELEERLKELEPFyneyleLKDAEKE 613

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  619 RDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQ-AALKLGDISHRLLEQQEDFAGKTAQYRQEMRHLHQVL 697
Cdd:PRK03918 614 LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRAELEELEKRREEIK 693

                        490       500
                 ....*....|....*....|....
gi 50083293  698 KDKQEvLDQALQQNREMEGELEVI 721
Cdd:PRK03918 694 KTLEK-LKEELEEREKAKKELEKL 716
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 260-496 2.69e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 2.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 260 ELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAApellyLRKQAQELVDENDGLKMTVHRLNVELSRYQTKFRHL 339
Cdd:COG4942  28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA-----LARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 340 SKEESLNIEGLPSKGPIPPWLLdikylsplLLAYEDMmkekdelnatlkEEMRMFRMRVQEVVKENEELHQELNKssavT 419
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLAL--------LLSPEDF------------LDAVRRLQYLKYLAPARREQAEELRA----D 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50083293 420 SEEWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAkthgQEKELAENREQLEILRAK 496
Cdd:COG4942 159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA----ELAELQQEAEELEALIAR 231
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 243-593 1.14e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   243 LKEENMDLNNMNQSLTL---ELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEvaapeLLYLRKQAQELVDENDGLK 319
Cdd:TIGR04523  91 LKKNKDKINKLNSDLSKinsEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTE-----IKKKEKELEKLNNKYNDLK 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   320 MTVHRLNVELsryqtkfrHLSKEESLNIEGLPSKgpiPPWLLDIKYLSPLLLayedmmKEKDELNATLKEEMRMFRMRVQ 399
Cdd:TIGR04523 166 KQKEELENEL--------NLLEKEKLNIQKNIDK---IKNKLLKLELLLSNL------KKKIQKNKSLESQISELKKQNN 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   400 EVVKENEELHQELNKSSAVTSEEWRQL-QTQAKLVLEENKLLLEQLEIQQRKAKdshqerlqeVSKLTKQLMLLEAKTHG 478
Cdd:TIGR04523 229 QLKDNIEKKQQEINEKTTEISNTQTQLnQLKDEQNKIKKQLSEKQKELEQNNKK---------IKELEKQLNQLKSEISD 299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   479 QEKELAEN-----REQLEILRAKCQELKTH-SDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEK---LTVLQAQK 549
Cdd:TIGR04523 300 LNNQKEQDwnkelKSELKNQEKKLEEIQNQiSQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKqneIEKLKKEN 379

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 50083293   550 KSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEV--------------LKKQVEK 593
Cdd:TIGR04523 380 QSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKlqqekellekeierLKETIIK 437
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 221-314 2.98e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  221 SPDITGRARQRYTEitrekfealkeENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEaEKASSQEVAAPE 300
Cdd:PRK00409 500 PENIIEEAKKLIGE-----------DKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEE-KKEKLQEEEDKL 567

                         90
                 ....*....|....
gi 50083293  301 LLYLRKQAQELVDE 314
Cdd:PRK00409 568 LEEAEKEAQQAIKE 581
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 421-767 1.21e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 1.21e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 421 EEWRQLQTQAKLV-LEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQE 499
Cdd:COG1196 213 ERYRELKEELKELeAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 500 LKTHsdgKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRK 579
Cdd:COG1196 293 LLAE---LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 580 SQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGyKK 659
Cdd:COG1196 370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE-AA 448

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 660 QAALKLGDISHRLLEQQEDFAGKTAQYRQEMRHLHQVLKDKQEVLDQALQQNREMEGELEVIWEStfRENRRIRELLQDT 739
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA--LLLAGLRGLAGAV 526

                       330       340
                ....*....|....*....|....*...
gi 50083293 740 LTRTGVQDNPRALVAPSLNGVSQADLLD 767
Cdd:COG1196 527 AVLIGVEAAYEAALEAALAAALQNIVVE 554
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 238-714 4.24e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.57  E-value: 4.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   238 EKFEALKEEN----MDLNNMNQSLTLELNTMK----QAMKELQLKLKgmeKEKRKLKEAEKASSQEVAAPEllylrKQAQ 309
Cdd:pfam05483 172 KKYEYEREETrqvyMDLNNNIEKMILAFEELRvqaeNARLEMHFKLK---EDHEKIQHLEEEYKKEINDKE-----KQVS 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   310 ELVDENDGLKMTVHRLNVELSRYQTKFRHLSKEESLNIEGLPS----KGPIPPWLLDIKYlsplllayedMMKEKDELNA 385
Cdd:pfam05483 244 LLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKEliekKDHLTKELEDIKM----------SLQRSMSTQK 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   386 TLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQLQT------------QAKLVLEENKLLLEQLEIQQR---- 449
Cdd:pfam05483 314 ALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEAttcsleellrteQQRLEKNEDQLKIITMELQKKssel 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   450 ----KAKDSHQERLQEVSKL--TKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHsDGKIAVEVHKSI------- 516
Cdd:pfam05483 394 eemtKFKNNKEVELEELKKIlaEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIH-DLEIQLTAIKTSeehylke 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   517 VNELKSQLQKEEEkeraemeelmeKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMG 596
Cdd:pfam05483 473 VEDLKTELEKEKL-----------KNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   597 NEMsahQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQAALKLGDISHrlLEQQ 676
Cdd:pfam05483 542 KEM---NLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE--LHQE 616

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 50083293   677 EDFAGKTAQYRQEMRHLHQVLKDKQEV-LDQALQQNREM 714
Cdd:pfam05483 617 NKALKKKGSAENKQLNAYEIKVNKLELeLASAKQKFEEI 655
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 449-740 4.69e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 4.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    449 RKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRakcQELKTHSDGKIAVEVHKSIVNELKSQLQKEE 528
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE---EELEQLRKELEELSRQISALRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    529 EKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANL 608
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    609 VGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKgyKKQAALKLgdISHRLLEQQEDFAGKTAQYRQ 688
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEA--LLNERASLEEALALLRSELEE 898

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 50083293    689 EMRHLHQVLKDKQEvLDQALQQNREMEGELEVIWEST-FRENR---RIRELLQDTL 740
Cdd:TIGR02168  899 LSEELRELESKRSE-LRRELEELREKLAQLELRLEGLeVRIDNlqeRLSEEYSLTL 953
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 370-622 1.07e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    370 LLAYEDMMKEKDELNATLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQLQ-TQAKLVLEENKllLEQLEIQQ 448
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQiLRERLANLERQ--LEELEAQL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    449 RKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGKiavevhKSIVNELKSQLQKee 528
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL------RSKVAQLELQIAS-- 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    529 ekeraemeeLMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKinRKSQKKIEVLKKQVEKAMGNEMSAHQYLANL 608
Cdd:TIGR02168  398 ---------LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEEL 466

                          250
                   ....*....|....
gi 50083293    609 VGLAENITQERDSL 622
Cdd:TIGR02168  467 REELEEAEQALDAA 480
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 399-608 1.90e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 1.90e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 399 QEVVKENEELHQELNKSSAVTSEEWRQLQTQAKLVLEEnkllLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHG 478
Cdd:COG4942  19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ----LAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 479 QEKELAENREQL-EILRAKCQ-------ELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKK 550
Cdd:COG4942  95 LRAELEAQKEELaELLRALYRlgrqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 50083293 551 SLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANL 608
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
238-721 2.68e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 2.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  238 EKFEALKEENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASsqevaaPELLYLRKQAQELVDENDG 317
Cdd:PRK03918 231 KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL------KELKEKAEEYIKLSEFYEE 304

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  318 LKMTVHRLNVELSRYQTKF----RHLSKEESLNIEGLPSKGPIPPWLLDIKYLSPLLLAYEDMMKEKDELNATLKE---- 389
Cdd:PRK03918 305 YLDELREIEKRLSRLEEEIngieERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltgl 384

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  390 EMRMFRMRVQEVVKENEELHQELNKSSAVTSEeWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERL-----QEVSK 464
Cdd:PRK03918 385 TPEKLEKELEELEKAKEEIEEEISKITARIGE-LKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELleeytAELKR 463

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  465 LTKQLMLLEAKthgqEKELAENREQLEILRAKCQELKTHsdgKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTV 544
Cdd:PRK03918 464 IEKELKEIEEK----ERKLRKELRELEKVLKKESELIKL---KELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK 536

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  545 LQAQKKSLLLEKNSLTEQNKALEaELERaqKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGL------AENITQE 618
Cdd:PRK03918 537 LKGEIKSLKKELEKLEELKKKLA-ELEK--KLDELEEELAELLKELEELGFESVEELEERLKELEPFyneyleLKDAEKE 613

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  619 RDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQ-AALKLGDISHRLLEQQEDFAGKTAQYRQEMRHLHQVL 697
Cdd:PRK03918 614 LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRAELEELEKRREEIK 693

                        490       500
                 ....*....|....*....|....
gi 50083293  698 KDKQEvLDQALQQNREMEGELEVI 721
Cdd:PRK03918 694 KTLEK-LKEELEEREKAKKELEKL 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 265-613 2.94e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 2.94e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 265 KQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAAPELLYLRKQAQELVDENDGLKMTVHRLNVELSRYQTKFRHLSKEEs 344
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL- 297

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 345 lnieglpskgpippwlldikylsplllayedmmkekdelnATLKEEMRMFRMRVQEVVKENEELHQELnkssavtsEEWR 424
Cdd:COG1196 298 ----------------------------------------ARLEQDIARLEERRRELEERLEELEEEL--------AELE 329

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 425 QLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHS 504
Cdd:COG1196 330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 505 DGKiavevhksivNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKI 584
Cdd:COG1196 410 EAL----------LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                       330       340
                ....*....|....*....|....*....
gi 50083293 585 EVLKKQVEKAMGNEMSAHQYLANLVGLAE 613
Cdd:COG1196 480 AELLEELAEAAARLLLLLEAEADYEGFLE 508
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 378-721 5.39e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.36  E-value: 5.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    378 KEKDELNATLKEEMRMFRMRVQEVVKENEELHQELnKSSAVTSEEWRQLQTQAK--------LVLEENKLLLEQLEIQQR 449
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQEL-KLKEQAKKALEYYQLKEKleleeeylLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    450 KAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEE 529
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    530 KERAEMEELMEKLTVLQAQKKslllEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANlv 609
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELK----ELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    610 gLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQAALKLGDISHRLLEQQEDF---AGKTAQY 686
Cdd:pfam02463  399 -LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELkksEDLLKET 477

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 50083293    687 RQEMRHLHQVLKDKQEVLDQALQQNREMEGELEVI 721
Cdd:pfam02463  478 QLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL 512
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
374-622 9.71e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 9.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  374 EDMMKEKDELNATLKEeMRMFRMRVQEVVKENEELH---------QELNKSSAV-TSEEWRQLQTQAKLVLEENKLLLEQ 443
Cdd:PRK02224 415 EELREERDELREREAE-LEATLRTARERVEEAEALLeagkcpecgQPVEGSPHVeTIEEDRERVEELEAELEDLEEEVEE 493

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  444 LEIQQRKAKDShQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGK--------IAVEVHKS 515
Cdd:PRK02224 494 VEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKreaaaeaeEEAEEARE 572

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  516 IVNELKSQLQKEEEKERAemeelMEKLTVLQAQKKSLLLEKNSLTEQNKAL-EAELER----AQKINRKSQKKIEVLKKQ 590
Cdd:PRK02224 573 EVAELNSKLAELKERIES-----LERIRTLLAAIADAEDEIERLREKREALaELNDERrerlAEKRERKRELEAEFDEAR 647

                        250       260       270
                 ....*....|....*....|....*....|..
gi 50083293  591 VEKAMGNEMSAHQYLANLVGLAENITQERDSL 622
Cdd:PRK02224 648 IEEAREDKERAEEYLEQVEEKLDELREERDDL 679
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 361-594 4.78e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 4.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    361 LDIKYLSPLLLAYEDMMKEKDELNATLKEEMRMFRMRVQEVVKENEELHQELNKSSAvtseEWRQLQTQAklvlEENKLL 440
Cdd:TIGR02169  667 LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEK----EIEQLEQEE----EKLKER 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    441 LEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAE-----NREQLEILRAKCQELKthsdgkiavEVHKS 515
Cdd:TIGR02169  739 LEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlSHSRIPEIQAELSKLE---------EEVSR 809

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    516 I---VNELKSQLQKEEEKER---AEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKK 589
Cdd:TIGR02169  810 IearLREIEQKLNRLTLEKEyleKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK 889


                   ....*
gi 50083293    590 QVEKA 594
Cdd:TIGR02169  890 ERDEL 894
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
403-622 9.86e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 9.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  403 KENEELHQELNkssavtseewrQLQTQAKLVLEEnkllLEQLEIQQRKAK----------DSHQERLQEVSKLTKQLMLL 472
Cdd:PRK02224 199 KEEKDLHERLN-----------GLESELAELDEE----IERYEEQREQARetrdeadevlEEHEERREELETLEAEIEDL 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  473 EAKTHGQEKELAENREQLEILRAKCQELKTHSDGKIA-----------VEVHKSIVNELKSQLQKEEEKERAEMEELMEK 541
Cdd:PRK02224 264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAeaglddadaeaVEARREELEDRDEELRDRLEECRVAAQAHNEE 343

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  542 LTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDS 621
Cdd:PRK02224 344 AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDE 423


                 .
gi 50083293  622 L 622
Cdd:PRK02224 424 L 424
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 370-655 2.12e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 2.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    370 LLAYEDMMKEKDELNATLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQL---QTQAKLVLEENKLLLEQLEI 446
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    447 QQRKAKDSHQERLQEVSKLTK----------QLMLLEAKTHGQEKELAENREQLEILRAKCQELKT-----------HSD 505
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEaeeelaeaeaEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerlesLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    506 GKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIE 585
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 50083293    586 VLKKQVEKAMGNEMSAHQYLANL-VGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVK 655
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLeVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 260-496 2.69e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 2.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 260 ELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAApellyLRKQAQELVDENDGLKMTVHRLNVELSRYQTKFRHL 339
Cdd:COG4942  28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA-----LARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 340 SKEESLNIEGLPSKGPIPPWLLdikylsplLLAYEDMmkekdelnatlkEEMRMFRMRVQEVVKENEELHQELNKssavT 419
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLAL--------LLSPEDF------------LDAVRRLQYLKYLAPARREQAEELRA----D 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 50083293 420 SEEWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAkthgQEKELAENREQLEILRAK 496
Cdd:COG4942 159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA----ELAELQQEAEELEALIAR 231
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 255-573 2.94e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 2.94e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 255 QSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAAPELLYLRKQAQELVdendgLKMTVHRLNVELSRYQT 334
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE-----LLAELARLEQDIARLEE 309

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 335 KFRHLSKEESLNIEglpskgpippwllDIKYLSPLLLAYEDMMKEKDELNATLKEEMRMFRMRVQEVVKENEELHQELNK 414
Cdd:COG1196 310 RRRELEERLEELEE-------------ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 415 SSAVTSEEWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILR 494
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 50083293 495 AKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERA 573
Cdd:COG1196 457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 369-622 3.10e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 3.10e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 369 LLLAYEDMMKEKDELNATLKEEMRMFRMRVQEVVKENEELhQELNKSSAVTSEEWRQLQTQAKLVLEENKLLLEQLEIQQ 448
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAEL-EELRLELEELELELEEAQAEEYELLAELARLEQDIARLE 308

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 449 RKAKDShQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGKIAVEVHKSI-VNELKSQLQKE 527
Cdd:COG1196 309 ERRREL-EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAeAEEELEELAEE 387

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 528 EEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLAN 607
Cdd:COG1196 388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                       250
                ....*....|....*
gi 50083293 608 LVGLAENITQERDSL 622
Cdd:COG1196 468 LLEEAALLEAALAEL 482
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 378-738 5.57e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 5.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    378 KEKDELnATLKEEMRMFRMRVQEVVKENEELHQELNKSsavtsEEWRQLQTqaKLVLEENKLLLEQLEI--QQRKAKDSH 455
Cdd:TIGR02169  174 KALEEL-EEVEENIERLDLIIDEKRQQLERLRREREKA-----ERYQALLK--EKREYEGYELLKEKEAleRQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    456 QERLQ-EVSKLTKQLMLLEAKTHGQEKELAENREQL------EILRAKCQELKTHSD---GKIAVEVHKSIVNELKSQLQ 525
Cdd:TIGR02169  246 LASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgeeEQLRVKEKIGELEAEiasLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    526 KEEEK---ERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAmGNEMSAH 602
Cdd:TIGR02169  326 KLEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL-KREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    603 QylanlvglaenitQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKvkgyKKQAALKLGDISHRLLEQQEDFAGK 682
Cdd:TIGR02169  405 K-------------RELDRLQEELQRLSEELADLNAAIAGIEAKINELEEE----KEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 50083293    683 TAQY---RQEMRHLHQVLKDKQEVLDQALQQNRemegelevIWESTFRENRRIRELLQD 738
Cdd:TIGR02169  468 EQELydlKEEYDRVEKELSKLQRELAEAEAQAR--------ASEERVRGGRAVEEVLKA 518
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 382-675 6.95e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 6.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    382 ELNATLKE-EMRMFRMRVQEVVKENEELHQELNKSSavtsEEWRQLQTQAKLV---LEENKLLLEQLEIQQRKAKDSHQE 457
Cdd:TIGR02168  217 ELKAELRElELALLVLRLEELREELEELQEELKEAE----EELEELTAELQELeekLEELRLEVSELEEEIEELQKELYA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    458 RLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDgkiAVEVHKSIVNELKSQLQKEEEKERAEMEE 537
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA---ELEEKLEELKEELESLEAELEELEAELEE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293    538 LMEKLTVLQAQ-------KKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAH-----QYL 605
Cdd:TIGR02168  370 LESRLEELEEQletlrskVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEleeleEEL 449

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 50083293    606 ANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLE---EKVKGYK------KQAALKLGDISHRLLEQ 675
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlqENLEGFSegvkalLKNQSGLSGILGVLSEL 528
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 521-725 8.45e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 8.45e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 521 KSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEK---AMGN 597
Cdd:COG3883  18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErarALYR 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 598 EMSAHQYLANLVGlAENITQERDSLMCLAKCLESEKDgVLNKVIKSNIRLGKLEEKVKGYKKQAALKLGDishrLLEQQE 677
Cdd:COG3883  98 SGGSVSYLDVLLG-SESFSDFLDRLSALSKIADADAD-LLEELKADKAELEAKKAELEAKLAELEALKAE----LEAAKA 171

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 50083293 678 DFAGKTAQYRQEMRHLHQVLKDKQEVLDQALQQNREMEGELEVIWEST 725
Cdd:COG3883 172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 243-593 1.14e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   243 LKEENMDLNNMNQSLTL---ELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEvaapeLLYLRKQAQELVDENDGLK 319
Cdd:TIGR04523  91 LKKNKDKINKLNSDLSKinsEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTE-----IKKKEKELEKLNNKYNDLK 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   320 MTVHRLNVELsryqtkfrHLSKEESLNIEGLPSKgpiPPWLLDIKYLSPLLLayedmmKEKDELNATLKEEMRMFRMRVQ 399
Cdd:TIGR04523 166 KQKEELENEL--------NLLEKEKLNIQKNIDK---IKNKLLKLELLLSNL------KKKIQKNKSLESQISELKKQNN 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   400 EVVKENEELHQELNKSSAVTSEEWRQL-QTQAKLVLEENKLLLEQLEIQQRKAKdshqerlqeVSKLTKQLMLLEAKTHG 478
Cdd:TIGR04523 229 QLKDNIEKKQQEINEKTTEISNTQTQLnQLKDEQNKIKKQLSEKQKELEQNNKK---------IKELEKQLNQLKSEISD 299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   479 QEKELAEN-----REQLEILRAKCQELKTH-SDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEK---LTVLQAQK 549
Cdd:TIGR04523 300 LNNQKEQDwnkelKSELKNQEKKLEEIQNQiSQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKqneIEKLKKEN 379

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 50083293   550 KSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEV--------------LKKQVEK 593
Cdd:TIGR04523 380 QSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKlqqekellekeierLKETIIK 437
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 380-595 1.14e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   380 KDELNATLKEE--MRMFRMRVQEVV-----KENEELHQELNKSSAVT-SEEWRQLQTQAKLVlEENKLLLEQLEIQQRKA 451
Cdd:pfam17380 359 KRELERIRQEEiaMEISRMRELERLqmerqQKNERVRQELEAARKVKiLEEERQRKIQQQKV-EMEQIRAEQEEARQREV 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   452 KDSHQERLQEVSKLTKQLMlleakthgqekelaENREQLEILRAKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKE 531
Cdd:pfam17380 438 RRLEEERAREMERVRLEEQ--------------ERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE 503

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 50083293   532 raemeelmEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAM 595
Cdd:pfam17380 504 --------RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559
PTZ00121 PTZ00121
MAEBL; Provisional
 388-594 1.19e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   388 KEEMRMFRMRVQEVVKENEELHQELNKSSA----VTSEEWRQLQtQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVS 463
Cdd:PTZ00121 1275 EEARKADELKKAEEKKKADEAKKAEEKKKAdeakKKAEEAKKAD-EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAE 1353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   464 KLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGKIAVEVHKSIVNELKSQlQKEEEKERAEMEELMEKLT 543
Cdd:PTZ00121 1354 AAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA-AAAKKKADEAKKKAEEKKK 1432

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 50083293   544 VLQAQKKSlllEKNSLTEQNKALEAELERAQKINRKSQ--KKIEVLKKQVEKA 594
Cdd:PTZ00121 1433 ADEAKKKA---EEAKKADEAKKKAEEAKKAEEAKKKAEeaKKADEAKKKAEEA 1482
PRK11281 PRK11281
mechanosensitive channel MscK;
282-588 1.99e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   282 KRKLKEAEKASSQEVAAPELLYLrKQAQELVDENDGLKMTVHRLNVELSRYQTKFRHLSKE---------ESLNIEGLPS 352
Cdd:PRK11281   50 KQKLLEAEDKLVQQDLEQTLALL-DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDndeetretlSTLSLRQLES 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   353 KgpippwlldikyLSPLLLAYEDMMKEKDELNA------TLKEemrmfrmRVQEVVKENEELHQELNKSSAVTSEEWRQL 426
Cdd:PRK11281  129 R------------LAQTLDQLQNAQNDLAEYNSqlvslqTQPE-------RAQAALYANSQRLQQIRNLLKGGKVGGKAL 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   427 Q-TQAKLVLEENKLLLEQLEIQQRKAKDSHQerLQEVskLTKQLMLLEAKTHGQEKELAE-----NREQLEILRAKCQEL 500
Cdd:PRK11281  190 RpSQRVLLQAEQALLNAQNDLQRKSLEGNTQ--LQDL--LQKQRDYLTARIQRLEHQLQLlqeaiNSKRLTLSEKTVQEA 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   501 KThSDGKIAVEVHKSIVNELKSQLQkeeekeraemeeLMEKLtvLQAQKKSlllekNSLTEQNKALEAELERAQKINRKS 580
Cdd:PRK11281  266 QS-QDEAARIQANPLVAQELEINLQ------------LSQRL--LKATEKL-----NTLTQQNLRVKNWLDRLTQSERNI 325


                  ....*...
gi 50083293   581 QKKIEVLK 588
Cdd:PRK11281  326 KEQISVLK 333
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 441-610 2.19e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 2.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  441 LEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKElaENREQLEILRAKCQELKTHSDgkiAVEVHKSIVNEL 520
Cdd:COG3096  855 HRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETLADRLE--ELREELDAAQEAQAFIQQHGK---ALAQLEPLVAVL 929

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  521 KS------QLQKEEEKERAEMEEL----------MEKLTVLQAQKKSLLLEKNSltEQNKALEAELERAQKINRKSQKKI 584
Cdd:COG3096  930 QSdpeqfeQLQADYLQAKEQQRRLkqqifalsevVQRRPHFSYEDAVGLLGENS--DLNEKLRARLEQAEEARREAREQL 1007

                        170       180
                 ....*....|....*....|....*.
gi 50083293  585 EVLKKQVEkamgnemSAHQYLANLVG 610
Cdd:COG3096 1008 RQAQAQYS-------QYNQVLASLKS 1026
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 221-314 2.98e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  221 SPDITGRARQRYTEitrekfealkeENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEaEKASSQEVAAPE 300
Cdd:PRK00409 500 PENIIEEAKKLIGE-----------DKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEE-KKEKLQEEEDKL 567

                         90
                 ....*....|....
gi 50083293  301 LLYLRKQAQELVDE 314
Cdd:PRK00409 568 LEEAEKEAQQAIKE 581
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
473-589 3.29e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.00  E-value: 3.29e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 473 EAKTHGQEKELAENREQLEILRAKCQELKTHsdgkiaVEVHKSIVNELKSQLQKeeekeraemeeLMEKLTVLQAQKKSL 552
Cdd:COG2433 398 EREKEHEERELTEEEEEIRRLEEQVERLEAE------VEELEAELEEKDERIER-----------LERELSEARSEERRE 460

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 50083293 553 LL---EKNSLTEQNKALEAELERAQKINRKSQKKIEVLKK 589
Cdd:COG2433 461 IRkdrEISRLDREIERLERELEEERERIEELKRKLERLKE 500
PLN02939 PLN02939
transferase, transferring glycosyl groups
 282-633 3.82e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 40.66  E-value: 3.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  282 KRKLKEAEKASSQEVAAPELLYLRKQAQELVDENDGLKMTVHRLNVELSRYQTKF-RHLSKEESLNIEGLPSKGP-IPPW 359
Cdd:PLN02939  39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSdDDHNRASMQRDEAIAAIDNeQQTN 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  360 LLDIKYLSPLLLayEDM--MKEKDELNATLKEEMRMFRM-RVQEVVKENEELHQELNKSSAVTSE--EWRQLQTQAKLVL 434
Cdd:PLN02939 119 SKDGEQLSDFQL--EDLvgMIQNAEKNILLLNQARLQALeDLEKILTEKEALQGKINILEMRLSEtdARIKLAAQEKIHV 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  435 EENKLLLEQL--EIQQRKAKDSHQERL--QEVSKLTKQLMLLEAKTHGQEKEL---AENREQLEILRAKCQELK-THSDG 506
Cdd:PLN02939 197 EILEEQLEKLrnELLIRGATEGLCVHSlsKELDVLKEENMLLKDDIQFLKAELievAETEERVFKLEKERSLLDaSLREL 276

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293  507 KIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVlQAQKKSLLLEKN-SLTEQNKALEAELERAqKINRKSQKKIE 585
Cdd:PLN02939 277 ESKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATN-QVEKAALVLDQNqDLRDKVDKLEASLKEA-NVSKFSSYKVE 354

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 50083293  586 VLKKQVEKAMGNEMSAHQYLANLVGLAENITQE-RDSLMCLAKclESEK 633
Cdd:PLN02939 355 LLQQKLKLLEERLQASDHEIHSYIQLYQESIKEfQDTLSKLKE--ESKK 401
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
396-594 4.43e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 4.43e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 396 MRVQEVVKENEELHQELNKSSAVTSEEWRQLQTQAKLVLEENKLL------LEQLEIQQRKAKDSHQERLQEVSKLTKQL 469
Cdd:COG4717  46 MLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYaelqeeLEELEEELEELEAELEELREELEKLEKLL 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 470 MLLEAkthgqEKELAENREQLEILRAKCQELKTHsdgkiaVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQK 549
Cdd:COG4717 126 QLLPL-----YQELEALEAELAELPERLEELEER------LEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 50083293 550 KSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKA 594
Cdd:COG4717 195 QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
238-602 4.51e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 4.51e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 238 EKFEALKEENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEV------AAPELLYLRKQAQEL 311
Cdd:COG4717 132 QELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeeelqdLAEELEELQQRLAEL 211

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 312 VDENDGLKMTVHRLNVELSRYQTKFRHLSKEESLNIEGLPSKgpIPPWLLDIKYLSPLLLAYEDMMKEKDELNATLKEEM 391
Cdd:COG4717 212 EEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLL--IAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 392 RMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQLQTQAKLVLEENKLLLEQLEIQQRKAkdshQERLQEVSKLTKQLML 471
Cdd:COG4717 290 FLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL----QELLREAEELEEELQL 365

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 472 LEAKTHGQ----------EKELAENREQLEILRAKCQELKTHSD--GKIAVEVHKSIVNELKSQLQKEEEKERAEMEELM 539
Cdd:COG4717 366 EELEQEIAallaeagvedEEELRAALEQAEEYQELKEELEELEEqlEELLGELEELLEALDEEELEEELEELEEELEELE 445

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 50083293 540 EKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAH 602
Cdd:COG4717 446 EELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 233-710 4.57e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 4.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   233 TEITREKFEA--LKEENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKE-----AEKASSQEVAAPELLYLR 305
Cdd:TIGR04523 145 TEIKKKEKELekLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELllsnlKKKIQKNKSLESQISELK 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   306 KQAQELVDENDGLKMTVHRLNVELSRYQTKFRHLSKEESLNIEGLpskgpippwlldikylsplllayEDMMKEKDELNA 385
Cdd:TIGR04523 225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL-----------------------SEKQKELEQNNK 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   386 TLKEEMRMFRMRVQEVVKENEELHQELNKssavtseewrqlqtQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKL 465
Cdd:TIGR04523 282 KIKELEKQLNQLKSEISDLNNQKEQDWNK--------------ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQL 347

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   466 TKQLMLLEAKTHGQEKELAENREQLEILR----AKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEK 541
Cdd:TIGR04523 348 KKELTNSESENSEKQRELEEKQNEIEKLKkenqSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   542 LTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDS 621
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   622 LMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQAALKLGDISHRLLEQQEDfagktaQYRQEMRHLHQ---VLK 698
Cdd:TIGR04523 508 LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEID------EKNKEIEELKQtqkSLK 581

                         490
                  ....*....|..
gi 50083293   699 DKQEVLDQALQQ 710
Cdd:TIGR04523 582 KKQEEKQELIDQ 593
PTZ00121 PTZ00121
MAEBL; Provisional
 260-583 5.24e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 5.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   260 ELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVA-----APEllylRKQAQELVDENDGLKMTVHRLNVELSRYQT 334
Cdd:PTZ00121 1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdeakkAEE----AKKADEAKKAEEKKKADELKKAEELKKAEE 1562

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   335 KFRHLSKEESLNIEGLPSKGPIPPWLLDIKYLSPLLLAYEDMMKEKDELNATLKEEmrmfRMRVQEVVKEnEELHQELNK 414
Cdd:PTZ00121 1563 KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA----KIKAEELKKA-EEEKKKVEQ 1637

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   415 SSAVTSEEWRQLQtQAKLVLEENKLLLEQL----EIQQRKAKDSHQERLQEvskltkqlmllEAKTHGQEKELAENREQL 490
Cdd:PTZ00121 1638 LKKKEAEEKKKAE-ELKKAEEENKIKAAEEakkaEEDKKKAEEAKKAEEDE-----------KKAAEALKKEAEEAKKAE 1705

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   491 EILRAKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAEL 570
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785

                         330
                  ....*....|...
gi 50083293   571 ERAQKINRKSQKK 583
Cdd:PTZ00121 1786 DEEDEKRRMEVDK 1798
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
385-512 5.26e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 40.23  E-value: 5.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293 385 ATLKEEMRMFRMRVQEVVKENEELHQELNkssavtseewRQLQTQAKLvleENKLLLEQLEIQQRKAKDshqerlQEVSK 464
Cdd:COG2433 409 TEEEEEIRRLEEQVERLEAEVEELEAELE----------EKDERIERL---ERELSEARSEERREIRKD------REISR 469

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 50083293 465 LTKQLMLLEakthgqeKELAENREQLEILRAKCQELKT-----HSDGKIAVEV 512
Cdd:COG2433 470 LDREIERLE-------RELEEERERIEELKRKLERLKElwkleHSGELVPVKV 515
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 230-660 7.49e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 39.62  E-value: 7.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   230 QRYTEITREKFEaLKEENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEV--AAPELLYLRKQ 307
Cdd:TIGR04523 211 QKNKSLESQISE-LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELeqNNKKIKELEKQ 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   308 AQELVDENDGLKM-----TVHRLNVELSRYQTKFRHLSKEESLNIeglpskgpippwlldiKYLSPLLLAYEDMMKEKDE 382
Cdd:TIGR04523 290 LNQLKSEISDLNNqkeqdWNKELKSELKNQEKKLEEIQNQISQNN----------------KIISQLNEQISQLKKELTN 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   383 L---NATLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQLQTQAKLvleeNKLLLEQLEIQQrkakdshqerl 459
Cdd:TIGR04523 354 SeseNSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKL----NQQKDEQIKKLQ----------- 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   460 QEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELK-THSDGKIAVEVHKSIVNELKS---QLQKEEEKERAEM 535
Cdd:TIGR04523 419 QEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDnTRESLETQLKVLSRSINKIKQnleQKQKELKSKEKEL 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   536 EELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAEleRAQKINRKSQKKIEVLKKQVEKAMGN-EMSAHQYLANLVGLAEN 614
Cdd:TIGR04523 499 KKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE--KKEKESKISDLEDELNKDDFELKKENlEKEIDEKNKEIEELKQT 576

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 50083293   615 IT---QERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQ 660
Cdd:TIGR04523 577 QKslkKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 369-574 9.50e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 38.97  E-value: 9.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   369 LLLAYEDMMKEKDELnatlKEEMRMFRMRVQEVVKEneelHQELNKSSAVTSEEWRQLQTQAKlvleenklllEQLEIQQ 448
Cdd:pfam09787  45 LTLELEELRQERDLL----REEIQKLRGQIQQLRTE----LQELEAQQQEEAESSREQLQELE----------EQLATER 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50083293   449 RKakdsHQERLQEVSKLTKQLMLLEAKthgQEKELAENREQLEILRAKCQELKTHSDGKiavEVHKSIVNELKSQLQKee 528
Cdd:pfam09787 107 SA----RREAEAELERLQEELRYLEEE---LRRSKATLQSRIKDREAEIEKLRNQLTSK---SQSSSSQSELENRLHQ-- 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 50083293   529 ekeraemeeLMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQ 574
Cdd:pfam09787 175 ---------LTETLIQKQTMLEALSTEKNSLVLQLERMEQQIKELQ 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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