inactive serine/threonine-protein kinase 19 isoform 2 [Homo sapiens]
Protein Classification
Stk19 family serine/threonine-protein kinase( domain architecture ID 10564673)
Stk19 family serine/threonine-protein kinase, similar to Homo sapiens serine/threonine-protein kinase 19 that acts as a key regulator of NRAS signaling by mediating phosphorylation of NRAS at 'Ser-89', thereby enhancing NRAS-binding to its downstream effectors
List of domain hits
| Name | Accession | Description | Interval | E-value | |||||
| Stk19 | pfam10494 | Serine-threonine protein kinase 19; This serine-threonine protein kinase number 19 is ... |
162-365 | 2.39e-35 | |||||
Serine-threonine protein kinase 19; This serine-threonine protein kinase number 19 is expressed from the MHC and predominantly in the nucleus. Protein kinases are involved in signal transduction pathways and play fundamental roles in the regulation of cell functions. This is a novel Ser/Thr protein kinase, that has Mn2+-dependent protein kinase activity that phosphorylates alpha -casein at Ser/Thr residues and histone at Ser residues. It can be covalently modified by the reactive ATP analogue 5'-p-fluorosulfonylbenzoyladenosine in the absence of ATP, and this modification is prevented in the presence of 1 mM ATP, indicating that the kinase domain of is capable of binding ATP. : Pssm-ID: 431315 Cd Length: 262 Bit Score: 130.11 E-value: 2.39e-35
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| Name | Accession | Description | Interval | E-value | |||||
| Stk19 | pfam10494 | Serine-threonine protein kinase 19; This serine-threonine protein kinase number 19 is ... |
162-365 | 2.39e-35 | |||||
Serine-threonine protein kinase 19; This serine-threonine protein kinase number 19 is expressed from the MHC and predominantly in the nucleus. Protein kinases are involved in signal transduction pathways and play fundamental roles in the regulation of cell functions. This is a novel Ser/Thr protein kinase, that has Mn2+-dependent protein kinase activity that phosphorylates alpha -casein at Ser/Thr residues and histone at Ser residues. It can be covalently modified by the reactive ATP analogue 5'-p-fluorosulfonylbenzoyladenosine in the absence of ATP, and this modification is prevented in the presence of 1 mM ATP, indicating that the kinase domain of is capable of binding ATP. Pssm-ID: 431315 Cd Length: 262 Bit Score: 130.11 E-value: 2.39e-35
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| Name | Accession | Description | Interval | E-value | |||||
| Stk19 | pfam10494 | Serine-threonine protein kinase 19; This serine-threonine protein kinase number 19 is ... |
162-365 | 2.39e-35 | |||||
Serine-threonine protein kinase 19; This serine-threonine protein kinase number 19 is expressed from the MHC and predominantly in the nucleus. Protein kinases are involved in signal transduction pathways and play fundamental roles in the regulation of cell functions. This is a novel Ser/Thr protein kinase, that has Mn2+-dependent protein kinase activity that phosphorylates alpha -casein at Ser/Thr residues and histone at Ser residues. It can be covalently modified by the reactive ATP analogue 5'-p-fluorosulfonylbenzoyladenosine in the absence of ATP, and this modification is prevented in the presence of 1 mM ATP, indicating that the kinase domain of is capable of binding ATP. Pssm-ID: 431315 Cd Length: 262 Bit Score: 130.11 E-value: 2.39e-35
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