NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|258679484|ref|NP_113550|]
View 

opioid growth factor receptor [Mus musculus]

Protein Classification

OGFr_N and KLF9_13_N-like domain-containing protein( domain architecture ID 12056876)

OGFr_N and KLF9_13_N-like domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 76-283 8.57e-152

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


:

Pssm-ID: 461383  Cd Length: 208  Bit Score: 435.99  E-value: 8.57e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   76 DCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRE 155
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  156 RLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHK 235
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 258679484  236 LPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLR 283
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 435-633 8.17e-14

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 75.11  E-value: 8.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 435 AEGDGVASNTQVQASALSPTPSE--CPESQKDGNGPEDPksqvGP--EDPKSQVgPEDPKSQVGPEDPKSqvgPEDPKgq 510
Cdd:PTZ00449 523 APGDKEGEEGEHEDSKESDEPKEggKPGETKEGEVGKKP----GPakEHKPSKI-PTLSKKPEFPKDPKH---PKDPE-- 592

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 511 vEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 590
Cdd:PTZ00449 593 -EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 258679484 591 QVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 633
Cdd:PTZ00449 672 KEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
PHA03169 super family cl27451
hypothetical protein; Provisional
 284-548 9.96e-04

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA03169:

Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.88  E-value: 9.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 284 RFRPQTISRPLMGLGQADKDEGPgdPSQEAGTQGRtcgsgRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPK 363
Cdd:PHA03169  34 GRRRGTAARAAKPAPPAPTTSGP--QVRAVAEQGH-----RQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPS 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 364 ESKKRKLEGNrqeqvpgEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASN 443
Cdd:PHA03169 107 PSGSAEELAS-------GLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP-------------PESHNPSPNQQPSSF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 444 TQVQASAlSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEdPKSQVGPEDPKGQVEPEDPKGQVGPE 523
Cdd:PHA03169 167 LQPSHED-SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPT-PQQAPSPNTQQAVEHEDEPTEPEREG 244

                        250       260
                 ....*....|....*....|....*
gi 258679484 524 DPkgQVGPEDPKGQVGPEDPKSQVG 548
Cdd:PHA03169 245 PP--FPGHRSHSYTVVGWKPSTRPG 267
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 76-283 8.57e-152

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 435.99  E-value: 8.57e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   76 DCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRE 155
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  156 RLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHK 235
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 258679484  236 LPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLR 283
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 435-633 8.17e-14

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 75.11  E-value: 8.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 435 AEGDGVASNTQVQASALSPTPSE--CPESQKDGNGPEDPksqvGP--EDPKSQVgPEDPKSQVGPEDPKSqvgPEDPKgq 510
Cdd:PTZ00449 523 APGDKEGEEGEHEDSKESDEPKEggKPGETKEGEVGKKP----GPakEHKPSKI-PTLSKKPEFPKDPKH---PKDPE-- 592

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 511 vEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 590
Cdd:PTZ00449 593 -EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 258679484 591 QVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 633
Cdd:PTZ00449 672 KEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 445-609 1.70e-12

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 70.18  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 445 QVQASALSPTPSECPESQKDG----NGPEDPKSQVGP--EDPKSQVG--PEDPKSQVGP--EDPKSQVG--PEDPKGQV- 511
Cdd:NF033839 309 EVKPEPETPKPEVKPQLEKPKpevkPQPEKPKPEVKPqlETPKPEVKpqPEKPKPEVKPqpEKPKPEVKpqPETPKPEVk 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 512 -EPEDPKGQVGP--EDPKGQVGP--EDPKGQVGP--EDPKSQVGPE----DPKSQVEPEDPKSQVEPedpksQVEPEDPK 580
Cdd:NF033839 389 pQPEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPQpekpKPEVKPQPEKPKPEVKP-----QPETPKPE 463

                        170       180
                 ....*....|....*....|....*....
gi 258679484 581 SQVGPEDPQSQVGPEQAASKSLGEDPDSD 609
Cdd:NF033839 464 VKPQPEKPKPEVKPQPEKPKPDNSKPQAD 492
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 491-607 7.76e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 58.38  E-value: 7.76e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 491 SQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSqvePEDPKSQVEPEDP 570
Cdd:NF038329 111 QQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQG---PAGKDGEAGAKGP 187

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 258679484 571 KSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPD 607
Cdd:NF038329 188 AGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGED 224
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 445-599 2.23e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 54.00  E-value: 2.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 445 QVQASALSPTPSECPEsqkdgngPEDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKGQV--EPE 514
Cdd:NF033839 364 EVKPQPEKPKPEVKPQ-------PETPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVkpQPE 436

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 515 DPKGQVGP--EDPKGQVGPedpkgQVGPEDPKSQVGPEDPKSQVEPEDPKsqvePEDPKSQVEPEDPKSQVGPEDPQSQV 592
Cdd:NF033839 437 KPKPEVKPqpEKPKPEVKP-----QPETPKPEVKPQPEKPKPEVKPQPEK----PKPDNSKPQADDKKPSTPNNLSKDKQ 507


                 ....*..
gi 258679484 593 GPEQAAS 599
Cdd:NF033839 508 PSNQAST 514
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
432-633 2.71e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 46.99  E-value: 2.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  432 EEGAEGDGVASNTQVQASALSPTP------SECPESQKDGNGPEDPkSQVGPEDPKSQVGPEDPKSQVGPEDPKS----- 500
Cdd:pfam03546  31 ESDSEEETPAAKTPLQAKPSGKTPqvraasAPAKESPRKGAPPVPP-GKTGPAAAQAQAGKPEEDSESSSEESDSdgetp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  501 ----------QVGPEDPKGQVEP-----EDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQV 565
Cdd:pfam03546 110 aaatlttspaQVKPLGKNSQVRPastvgKGPSGKGANPAPPGKAGSAAPLVQVGKKEEDSESSSEESDSEGEAPPAATQA 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 258679484  566 EPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSmSESEELARIEASVEPPKP 633
Cdd:pfam03546 190 KPSGKILQVRPASGPAKGAAPAPPQKAGPVATQVKAERSKEDSESSEES-SDSEEEAPAAATPAQAKP 256
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 469-633 3.83e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 46.69  E-value: 3.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 469 EDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPkGQVEPEDPKGQVGPEDPkgqvgPEDPKGQVGPEDPKSQVG 548
Cdd:NF033839 249 DNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEP-GNKKPSAPKPGMQPSPQ-----PEKKEVKPEPETPKPEVK 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 549 PEDPKSQVEPEDpksqvEPEDPKSQV-------------EPEDPKSQVGP--EDPQSQVGPEQAASKSlGEDPDSDTTGT 613
Cdd:NF033839 323 PQLEKPKPEVKP-----QPEKPKPEVkpqletpkpevkpQPEKPKPEVKPqpEKPKPEVKPQPETPKP-EVKPQPEKPKP 396

                        170       180
                 ....*....|....*....|
gi 258679484 614 SMSESEELARIEASVEPPKP 633
Cdd:NF033839 397 EVKPQPEKPKPEVKPQPEKP 416
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 275-591 1.04e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 45.76  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   275 VWGPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPS-QEAGTQGRTCGSGRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQ 353
Cdd:TIGR00927  610 LWVKEQLSRRPVAKVMALGDLSKGDVAEAEHTGERTgEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAER 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   354 RHEAKSPSPKESKKRKLEGnrqEQVPGEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEqpclvarvaNEVRKRRKVEe 433
Cdd:TIGR00927  690 KGEQEGEGEIEAKEADHKG---ETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGE---------GEAEGKHEVE- 756

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   434 gAEGDGVASNTQVQASALSPTPSECPESQKDGNGpeDPKSQVGPEDPKSQVGPEDPKSQV-GPEDPKSQVGPEDPKGQVE 512
Cdd:TIGR00927  757 -TEGDRKETEHEGETEAEGKEDEDEGEIQAGEDG--EMKGDEGAEGKVEHEGETEAGEKDeHEGQSETQADDTEVKDETG 833

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258679484   513 PEDPKGQVGPEDPKGQVGPEDPKGQVGPEDpksqvgpEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQ 591
Cdd:TIGR00927  834 EQELNAENQGEAKQDEKGVDGGGGSDGGDS-------EEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 387-517 2.30e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 44.23  E-value: 2.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 387 VSEVEKIALNLEGCALSPTSQEPREAEqpclVARVANEVRKRRKVEEGAEGDGVASNTQVQASALSPTPSECPESQKDGN 466
Cdd:NF033838 358 VKEEAKEPRNEEKIKQAKAKVESKKAE----ATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAP 433

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 258679484 467 GPEDPKSQVGPEDPKSQVGPEDpKSQVGPEDPK--SQVGPEDPKGQVEPEDPK 517
Cdd:NF033838 434 KPEKPAEQPKAEKPADQQAEED-YARRSEEEYNrlTQQQPPKTEKPAQPSTPK 485
PHA03169 PHA03169
hypothetical protein; Provisional
 284-548 9.96e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.88  E-value: 9.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 284 RFRPQTISRPLMGLGQADKDEGPgdPSQEAGTQGRtcgsgRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPK 363
Cdd:PHA03169  34 GRRRGTAARAAKPAPPAPTTSGP--QVRAVAEQGH-----RQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPS 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 364 ESKKRKLEGNrqeqvpgEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASN 443
Cdd:PHA03169 107 PSGSAEELAS-------GLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP-------------PESHNPSPNQQPSSF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 444 TQVQASAlSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEdPKSQVGPEDPKGQVEPEDPKGQVGPE 523
Cdd:PHA03169 167 LQPSHED-SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPT-PQQAPSPNTQQAVEHEDEPTEPEREG 244

                        250       260
                 ....*....|....*....|....*
gi 258679484 524 DPkgQVGPEDPKGQVGPEDPKSQVG 548
Cdd:PHA03169 245 PP--FPGHRSHSYTVVGWKPSTRPG 267
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 76-283 8.57e-152

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 435.99  E-value: 8.57e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   76 DCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRE 155
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  156 RLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHK 235
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 258679484  236 LPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLR 283
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 435-633 8.17e-14

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 75.11  E-value: 8.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 435 AEGDGVASNTQVQASALSPTPSE--CPESQKDGNGPEDPksqvGP--EDPKSQVgPEDPKSQVGPEDPKSqvgPEDPKgq 510
Cdd:PTZ00449 523 APGDKEGEEGEHEDSKESDEPKEggKPGETKEGEVGKKP----GPakEHKPSKI-PTLSKKPEFPKDPKH---PKDPE-- 592

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 511 vEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 590
Cdd:PTZ00449 593 -EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 258679484 591 QVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 633
Cdd:PTZ00449 672 KEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 445-609 1.70e-12

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 70.18  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 445 QVQASALSPTPSECPESQKDG----NGPEDPKSQVGP--EDPKSQVG--PEDPKSQVGP--EDPKSQVG--PEDPKGQV- 511
Cdd:NF033839 309 EVKPEPETPKPEVKPQLEKPKpevkPQPEKPKPEVKPqlETPKPEVKpqPEKPKPEVKPqpEKPKPEVKpqPETPKPEVk 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 512 -EPEDPKGQVGP--EDPKGQVGP--EDPKGQVGP--EDPKSQVGPE----DPKSQVEPEDPKSQVEPedpksQVEPEDPK 580
Cdd:NF033839 389 pQPEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPQpekpKPEVKPQPEKPKPEVKP-----QPETPKPE 463

                        170       180
                 ....*....|....*....|....*....
gi 258679484 581 SQVGPEDPQSQVGPEQAASKSLGEDPDSD 609
Cdd:NF033839 464 VKPQPEKPKPEVKPQPEKPKPDNSKPQAD 492
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 403-632 1.06e-11

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 68.18  E-value: 1.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 403 SPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASNTQVQASALsPTPSECPESQKDGNGPEDPKSqvgPEDPKS 482
Cdd:PTZ00449 537 SKESDEPKEGGKP-------------GETKEGEVGKKPGPAKEHKPSKI-PTLSKKPEFPKDPKHPKDPEE---PKKPKR 599

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 483 QVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPK--------- 553
Cdd:PTZ00449 600 PRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKfkekfyddy 679

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 554 ------------------------SQVEPEDPKSQ---------VEPEDPKSQVEP-EDPKSQvGPEDPQSQVGPEQAAS 599
Cdd:PTZ00449 680 ldaaaksketkttvvldesfesilKETLPETPGTPfttprplppKLPRDEEFPFEPiGDPDAE-QPDDIEFFTPPEEERT 758

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 258679484 600 ---KSLGEDPDSDTTGTSMSESEELARIEASVEPPK 632
Cdd:PTZ00449 759 ffhETPADTPLPDILAEEFKEEDIHAETGEPDEAMK 794
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 491-607 7.76e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 58.38  E-value: 7.76e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 491 SQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSqvePEDPKSQVEPEDP 570
Cdd:NF038329 111 QQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQG---PAGKDGEAGAKGP 187

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 258679484 571 KSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPD 607
Cdd:NF038329 188 AGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGED 224
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 445-599 2.23e-07

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 54.00  E-value: 2.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 445 QVQASALSPTPSECPEsqkdgngPEDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKGQV--EPE 514
Cdd:NF033839 364 EVKPQPEKPKPEVKPQ-------PETPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVkpQPE 436

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 515 DPKGQVGP--EDPKGQVGPedpkgQVGPEDPKSQVGPEDPKSQVEPEDPKsqvePEDPKSQVEPEDPKSQVGPEDPQSQV 592
Cdd:NF033839 437 KPKPEVKPqpEKPKPEVKP-----QPETPKPEVKPQPEKPKPEVKPQPEK----PKPDNSKPQADDKKPSTPNNLSKDKQ 507


                 ....*..
gi 258679484 593 GPEQAAS 599
Cdd:NF033839 508 PSNQAST 514
PHA03169 PHA03169
hypothetical protein; Provisional
 426-633 2.72e-06

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 49.97  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 426 RKRRKVEEGAEGDGVASNTQVQASALS---PTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQV 502
Cdd:PHA03169  38 GTAARAAKPAPPAPTTSGPQVRAVAEQghrQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASG 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 503 GPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDP-----KGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQvEPE 577
Cdd:PHA03169 118 LSPENTSGSSPESPASHSPPPSPPSHPGPHEPappesHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPP-QSE 196

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 258679484 578 DPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEAsvEPPKP 633
Cdd:PHA03169 197 TPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGP--PFPGH 250
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
432-633 2.71e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 46.99  E-value: 2.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  432 EEGAEGDGVASNTQVQASALSPTP------SECPESQKDGNGPEDPkSQVGPEDPKSQVGPEDPKSQVGPEDPKS----- 500
Cdd:pfam03546  31 ESDSEEETPAAKTPLQAKPSGKTPqvraasAPAKESPRKGAPPVPP-GKTGPAAAQAQAGKPEEDSESSSEESDSdgetp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  501 ----------QVGPEDPKGQVEP-----EDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQV 565
Cdd:pfam03546 110 aaatlttspaQVKPLGKNSQVRPastvgKGPSGKGANPAPPGKAGSAAPLVQVGKKEEDSESSSEESDSEGEAPPAATQA 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 258679484  566 EPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSmSESEELARIEASVEPPKP 633
Cdd:pfam03546 190 KPSGKILQVRPASGPAKGAAPAPPQKAGPVATQVKAERSKEDSESSEES-SDSEEEAPAAATPAQAKP 256
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 469-633 3.83e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 46.69  E-value: 3.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 469 EDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPkGQVEPEDPKGQVGPEDPkgqvgPEDPKGQVGPEDPKSQVG 548
Cdd:NF033839 249 DNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEP-GNKKPSAPKPGMQPSPQ-----PEKKEVKPEPETPKPEVK 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 549 PEDPKSQVEPEDpksqvEPEDPKSQV-------------EPEDPKSQVGP--EDPQSQVGPEQAASKSlGEDPDSDTTGT 613
Cdd:NF033839 323 PQLEKPKPEVKP-----QPEKPKPEVkpqletpkpevkpQPEKPKPEVKPqpEKPKPEVKPQPETPKP-EVKPQPEKPKP 396

                        170       180
                 ....*....|....*....|
gi 258679484 614 SMSESEELARIEASVEPPKP 633
Cdd:NF033839 397 EVKPQPEKPKPEVKPQPEKP 416
PHA03169 PHA03169
hypothetical protein; Provisional
 432-612 4.21e-05

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 46.50  E-value: 4.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 432 EEGAEGDGVASNTQVQASALSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPksqvGPEDPKSQVGPEDPKGQV 511
Cdd:PHA03169  92 PSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEP----APPESHNPSPNQQPSSFL 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 512 EPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQvEPEDPKSQVEPEDPKSQVGPEDPQS- 590
Cdd:PHA03169 168 QPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQ-QAPSPNTQQAVEHEDEPTEPEREGPp 246

                        170       180
                 ....*....|....*....|..
gi 258679484 591 QVGPEQAASKSLGEDPDSDTTG 612
Cdd:PHA03169 247 FPGHRSHSYTVVGWKPSTRPGG 268
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 468-594 6.39e-05

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 44.05  E-value: 6.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  468 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQV 547
Cdd:pfam15140  49 PLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEMKPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETI 128

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 258679484  548 GPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGP 594
Cdd:pfam15140 129 PKENESPEIHPLEGSQEIEPLEPVQLIEPLGEVEQIQPLETVPKENP 175
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 468-600 9.48e-05

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 43.66  E-value: 9.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  468 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQV 547
Cdd:pfam15140  40 DLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEMKPLGTAENILPLEAAREIHPLEAVGKI 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 258679484  548 GPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASK 600
Cdd:pfam15140 120 EPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQLIEPLGEVEQIQPLETVPK 172
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 275-591 1.04e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 45.76  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   275 VWGPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPS-QEAGTQGRTCGSGRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQ 353
Cdd:TIGR00927  610 LWVKEQLSRRPVAKVMALGDLSKGDVAEAEHTGERTgEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAER 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   354 RHEAKSPSPKESKKRKLEGnrqEQVPGEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEqpclvarvaNEVRKRRKVEe 433
Cdd:TIGR00927  690 KGEQEGEGEIEAKEADHKG---ETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGE---------GEAEGKHEVE- 756

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484   434 gAEGDGVASNTQVQASALSPTPSECPESQKDGNGpeDPKSQVGPEDPKSQVGPEDPKSQV-GPEDPKSQVGPEDPKGQVE 512
Cdd:TIGR00927  757 -TEGDRKETEHEGETEAEGKEDEDEGEIQAGEDG--EMKGDEGAEGKVEHEGETEAGEKDeHEGQSETQADDTEVKDETG 833

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258679484   513 PEDPKGQVGPEDPKGQVGPEDPKGQVGPEDpksqvgpEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQ 591
Cdd:TIGR00927  834 EQELNAENQGEAKQDEKGVDGGGGSDGGDS-------EEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 400-623 1.96e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 400 CALSPTSQEPREAEQPCLVARVANEVRKRRKVEEGAEGD-----GVASNTQVQASALSPTPSECPESQKDGNGPEDPKSQ 474
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPaapapAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 475 VGPEDPKsqVGPEDPKSQVGPEDPKSQVGPEDPKGQvePEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKS 554
Cdd:PRK07764 666 GDGWPAK--AGGAAPAAPPPAPAPAAPAAPAGAAPA--QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPL 741

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258679484 555 QVEPEDPKsqvEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTgTSMSESEELAR 623
Cdd:PRK07764 742 PPEPDDPP---DPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDD-EDRRDAEEVAM 806
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 387-517 2.30e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 44.23  E-value: 2.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 387 VSEVEKIALNLEGCALSPTSQEPREAEqpclVARVANEVRKRRKVEEGAEGDGVASNTQVQASALSPTPSECPESQKDGN 466
Cdd:NF033838 358 VKEEAKEPRNEEKIKQAKAKVESKKAE----ATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAP 433

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 258679484 467 GPEDPKSQVGPEDPKSQVGPEDpKSQVGPEDPK--SQVGPEDPKGQVEPEDPK 517
Cdd:NF033838 434 KPEKPAEQPKAEKPADQQAEED-YARRSEEEYNrlTQQQPPKTEKPAQPSTPK 485
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 477-633 2.87e-04

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 42.12  E-value: 2.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  477 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQV 556
Cdd:pfam15140   4 PSRPTSEIQPLKGVREIEPPQPGGKDDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEI 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 258679484  557 EPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 633
Cdd:pfam15140  84 EPPQAASEMKPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQLIEPLGE 160
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 455-601 6.98e-04

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 40.96  E-value: 6.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  455 PSECPESQKDGN-GPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPED 533
Cdd:pfam15140  17 VREIEPPQPGGKdDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEMKPLG 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 258679484  534 PKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKS 601
Cdd:pfam15140  97 TAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQLIEPLGEVEQI 164
PHA03169 PHA03169
hypothetical protein; Provisional
 284-548 9.96e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.88  E-value: 9.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 284 RFRPQTISRPLMGLGQADKDEGPgdPSQEAGTQGRtcgsgRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPK 363
Cdd:PHA03169  34 GRRRGTAARAAKPAPPAPTTSGP--QVRAVAEQGH-----RQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPS 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 364 ESKKRKLEGNrqeqvpgEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASN 443
Cdd:PHA03169 107 PSGSAEELAS-------GLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP-------------PESHNPSPNQQPSSF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 444 TQVQASAlSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEdPKSQVGPEDPKGQVEPEDPKGQVGPE 523
Cdd:PHA03169 167 LQPSHED-SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPT-PQQAPSPNTQQAVEHEDEPTEPEREG 244

                        250       260
                 ....*....|....*....|....*
gi 258679484 524 DPkgQVGPEDPKGQVGPEDPKSQVG 548
Cdd:PHA03169 245 PP--FPGHRSHSYTVVGWKPSTRPG 267
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 467-595 1.06e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.38  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  467 GPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQ 546
Cdd:PRK10263  365 GPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAG 444

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 258679484  547 vGPEDPKSQVEPEDPKSQVEPEDPKSQ-VEPEDPKSQVGPEDPQSQVGPE 595
Cdd:PRK10263  445 -NAWQAEEQQSTFAPQSTYQTEQTYQQpAAQEPLYQQPQPVEQQPVVEPE 493
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 431-613 3.46e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 40.35  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 431 VEEGAEGDGVASNTQVQASALSPTPsecPESQKDGNGPEDPKSQVGPEDPK-SQVGPEDPKSQVGPEDPKSQVGPEDPKg 509
Cdd:PRK13108 292 VDEALEREPAELAAAAVASAASAVG---PVGPGEPNQPDDVAEAVKAEVAEvTDEVAAESVVQVADRDGESTPAVEETS- 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484 510 qvEPEDPKGQvgPEDPKGQvGPEDPKgqvgPEDPKSQVGPEDPKSQvEPEDPkSQVEPEDPksqvEPEDPKSQVGPEDPQ 589
Cdd:PRK13108 368 --EADIEREQ--PGDLAGQ-APAAHQ----VDAEAASAAPEEPAAL-ASEAH-DETEPEVP----EKAAPIPDPAKPDEL 432

                        170       180
                 ....*....|....*....|....
gi 258679484 590 SQVGPEQAASKSLGEDPDSDTTGT 613
Cdd:PRK13108 433 AVAGPGDDPAEPDGIRRQDDFSSR 456
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 468-599 3.51e-03

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 39.04  E-value: 3.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  468 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQV 547
Cdd:pfam15140  13 PLKGVREIEPPQPGGKDDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEM 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 258679484  548 GPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAAS 599
Cdd:pfam15140  93 KPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQ 144
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 459-599 4.95e-03

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 38.27  E-value: 4.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  459 PESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQV 538
Cdd:pfam15140  13 PLKGVREIEPPQPGGKDDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEM 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 258679484  539 GPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAAS 599
Cdd:pfam15140  93 KPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQ 153
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 453-633 6.44e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.77  E-value: 6.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  453 PTPSECPESQKDGNGPEDPKS--QVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPK--GQVGPEDPKGQ 528
Cdd:PHA03307   73 PGPGTEAPANESRSTPTWSLStlAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRpvGSPGPPPAASP 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  529 VGPEDPKGQVgPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDS 608
Cdd:PHA03307  153 PAAGASPAAV-ASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADD 231

                         170       180
                  ....*....|....*....|....*
gi 258679484  609 DTTGTSMSESEELARIEASVEPPKP 633
Cdd:PHA03307  232 AGASSSDSSSSESSGCGWGPENECP 256
FAM47 pfam14642
FAM47 family; The function of this Chordate family of proteins is not known.
 486-583 8.37e-03

FAM47 family; The function of this Chordate family of proteins is not known.


Pssm-ID: 405345 [Multi-domain]  Cd Length: 257  Bit Score: 38.70  E-value: 8.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679484  486 PEDPKSQVgpEDPKSQVGPEdpKGQVEPEDPK----GQVGPEDPKGQVG--PEDPkgqvgPEDPKSQVGPEDPK---SQV 556
Cdd:pfam14642 152 PLDPERKL--EDAGSCEGQE--KTTDEPTEPGkypcGEFSPRPPETRVSclPPEP-----PKTPVSSLRPEPPEtgvSHL 222

                          90       100       110
                  ....*....|....*....|....*....|...
gi 258679484  557 EPEDPKSQVE------PEDPKSQVEPEDPKSQV 583
Cdd:pfam14642 223 RPQPPKTQVSslhlepPETGVSHLRPEPPKTQV 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH