|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
27-815 |
1.06e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 1.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 27 LEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNETQLLEK 106
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 107 EMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKL--TME 184
Cdd:TIGR02168 324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnnEIE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 185 YNEKRK-LLDSELTETLSAQLELDKAAQ--DFRKIHLERQELIQQWENTIEQ---MQRRDQEIDNCALALSRIKQEAREK 258
Cdd:TIGR02168 404 RLEARLeRLEDRRERLQQEIEELLKKLEeaELKELQAELEELEEELEELQEElerLEEALEELREELEEAEQALDAAERE 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 259 EGVVKEKIKFLENEVENNieyeRKISVAERKVSKcrmdyqrhegNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKD 338
Cdd:TIGR02168 484 LAQLQARLDSLERLQENL----EGFSEGVKALLK----------NQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQA 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 339 IFDETLRLQKLkhhneVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDvLFKKVQELQNEIAKEKA 418
Cdd:TIGR02168 550 VVVENLNAAKK-----AIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD-LVKFDPKLRKALSYLLG 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 419 LVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRL--KGEI--NSEEKQALEAKILELKKTMDEK 494
Cdd:TIGR02168 624 GVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIeeLEEKIEELEEKIAELEKALAEL 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 495 KSTLSLLESQIKKLhndlyfikksngknNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRAREL 574
Cdd:TIGR02168 704 RKELEELEEELEQL--------------RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 575 LYSKAEEVLSLEKRKQQLGKDMEERAEEIKVhkamLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEiLTVVMLPPEG 654
Cdd:TIGR02168 770 LEEAEEELAEAEAEIEELEAQIEQLKEELKA----LREALDELRAELTLLNEEAANLRERLESLERRIA-ATERRLEDLE 844
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 655 EEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLNScnsnykqsfkkvtpssdeyaLKIQLEEQKR 734
Cdd:TIGR02168 845 EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS--------------------ELEELSEELR 904
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 735 TADERYRCKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRitkqcgRLRREIRILK 814
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE------EARRRLKRLE 978
|
.
gi 21312922 815 Q 815
Cdd:TIGR02168 979 N 979
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
27-646 |
2.00e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 61.57 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 27 LEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNETQLLEK 106
Cdd:TIGR04523 73 SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 107 EMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQqddnKIRALTLQLEKLTMEYN 186
Cdd:TIGR04523 153 ELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQ----KNKSLESQISELKKQNN 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 187 EKRKLLDSEltetlsaQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREkegvVKEKI 266
Cdd:TIGR04523 229 QLKDNIEKK-------QQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQ----LKSEI 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 267 KFLENEVENNIEYERK--ISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDIfdetl 344
Cdd:TIGR04523 298 SDLNNQKEQDWNKELKseLKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEI----- 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 345 rlQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQlgivKDVLFKKVQELQNEIAKEKALVSEIE 424
Cdd:TIGR04523 373 --EKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE----KELLEKEIERLKETIIKNNSEIKDLT 446
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 425 GTRSSLKHLNKQLhkldfetlkqqeimysqDFYIQQVERRMSRLKGEINSeEKQALEAKilelKKTMDEKKSTLSLLESQ 504
Cdd:TIGR04523 447 NQDSVKELIIKNL-----------------DNTRESLETQLKVLSRSINK-IKQNLEQK----QKELKSKEKELKKLNEE 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 505 IKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKraRELLYSKAEEVLS 584
Cdd:TIGR04523 505 KKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKE--IEELKQTQKSLKK 582
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21312922 585 LEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILT 646
Cdd:TIGR04523 583 KQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
29-611 |
2.86e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.77 E-value: 2.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 29 DQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQS-LYKARESEIESEEHFKAIAERELgrvknETQLLEKE 107
Cdd:PRK03918 179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREeLEKLEKEVKELEELKEEIEELEK-----ELESLEGS 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 108 MAIIRERKSQMENNIFKTTQKLDDLKCQmnwdqqalEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTMEYNE 187
Cdd:PRK03918 254 KRKLEEKIRELEERIEELKKEIEELEEK--------VKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEING 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 188 KRKLLD------SELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRD----QEIDNCALALSRIKQEARE 257
Cdd:PRK03918 326 IEERIKeleekeERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTgltpEKLEKELEELEKAKEEIEE 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 258 KEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNR--SQLKDELDTLKTTLNRTSSDLQALRKNISKV 335
Cdd:PRK03918 406 EISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKEllEEYTAELKRIEKELKEIEEKERKLRKELREL 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 336 KKDIFDET--LRLQKLKHHNEVVKHKLKMITEKTLsiEEKATNMEDMLKEeekgLKEVEVQLGIVKDVLfKKVQELQNEI 413
Cdd:PRK03918 486 EKVLKKESelIKLKELAEQLKELEEKLKKYNLEEL--EKKAEEYEKLKEK----LIKLKGEIKSLKKEL-EKLEELKKKL 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 414 AkekALVSEIEGTRSSLKHLNKQLHKLDFETLKQ--QEIMYSQDFYIQQVERRMSRlkgeinsEEKQALEAKILELKKTM 491
Cdd:PRK03918 559 A---ELEKKLDELEEELAELLKELEELGFESVEEleERLKELEPFYNEYLELKDAE-------KELEREEKELKKLEEEL 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 492 DEKKSTLSLLESQIKKLHNDLYFIKKSngKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDmmIEDNLLKLqvKRA 571
Cdd:PRK03918 629 DKAFEELAETEKRLEELRKELEELEKK--YSEEEYEELREEYLELSRELAGLRAELEELEKRREE--IKKTLEKL--KEE 702
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 21312922 572 RELLYSKAEEVLSLEKRKqqlgKDMEERAEEIKVHKAMLT 611
Cdd:PRK03918 703 LEEREKAKKELEKLEKAL----ERVEELREKVKKYKALLK 738
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
286-840 |
4.75e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 4.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 286 AERKVSKCRMDYQRHEGNRSQLKDELDTLKTTlNRTSSDLQALRKNISKVKKDIFdeTLRLQKLKHHNEVVKHKLKMITE 365
Cdd:TIGR02168 177 TERKLERTRENLDRLEDILNELERQLKSLERQ-AEKAERYKELKAELRELELALL--VLRLEELREELEELQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 366 KTLSIEEKATNMEDMLKEEEKGLKEVEVQLgivkDVLFKKVQELQNEIAKekaLVSEIEGTRSSLKHLNKQLHKLD--FE 443
Cdd:TIGR02168 254 ELEELTAELQELEEKLEELRLEVSELEEEI----EELQKELYALANEISR---LEQQKQILRERLANLERQLEELEaqLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 444 TLKQQEIMYSQDFyiQQVERRMSRLKGEINS---------EEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYF 514
Cdd:TIGR02168 327 ELESKLDELAEEL--AELEEKLEELKEELESleaeleeleAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 515 IKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDnlLKLQVKRARELLYSKAEEVLSLEKRKQQLGK 594
Cdd:TIGR02168 405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE--LQEELERLEEALEELREELEEAEQALDAAER 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 595 DMEERAEEIKVHKAMLTSQ------IRCVEQQRKTMSSeFHERLSKIDKLKNRYEILTVVMLPPEGEE---EKTQSYYVI 665
Cdd:TIGR02168 483 ELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSG-ILGVLSELISVDEGYEAAIEAALGGRLQAvvvENLNAAKKA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 666 KAAQEKEELQR-----EGDSLDAKINKAEKEIYALQN-TLQVLNSCNSNYKQSFKKVTPSSDEYA----LKIQLEEQKRT 735
Cdd:TIGR02168 562 IAFLKQNELGRvtflpLDSIKGTEIQGNDREILKNIEgFLGVAKDLVKFDPKLRKALSYLLGGVLvvddLDNALELAKKL 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 736 aDERYR---------------------------CKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKE 788
Cdd:TIGR02168 642 -RPGYRivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 21312922 789 TEEQKPKLQRITKQCGRLRREIRILKQTDNETLEEQDIQLREIIQFHKDIDQ 840
Cdd:TIGR02168 721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
21-815 |
5.47e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.05 E-value: 5.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 21 NQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTShlknvnqeflftqslykARESEIESEEHfkaiaerelgrVKNE 100
Cdd:pfam15921 95 NESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMAD-----------------IRRRESQSQED-----------LRNQ 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 101 TQLLEKEMAIIRERKSQMENNifkTTQKLDDLKCQMNWDQQAL-EAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLE 179
Cdd:pfam15921 147 LQNTVHELEAAKCLKEDMLED---SNTQIEQLRKMMLSHEGVLqEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAIS 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 180 KLTMEYNEKRKLLDSELTeTLSAQLELDKAAQDfRKIHLerqeLIQQWENTIEQMQrRDQEIDncALALSRIKQEAREKE 259
Cdd:pfam15921 224 KILRELDTEISYLKGRIF-PVEDQLEALKSESQ-NKIEL----LLQQHQDRIEQLI-SEHEVE--ITGLTEKASSARSQA 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 260 GVVKEKIKFLENEVEN-NIEYERKISVAERKVSKCRMDYQrhEGNRSqLKDELDTLKTTLNRTSSDLQALRKNISKVKKD 338
Cdd:pfam15921 295 NSIQSQLEIIQEQARNqNSMYMRQLSDLESTVSQLRSELR--EAKRM-YEDKIEELEKQLVLANSELTEARTERDQFSQE 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 339 IFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKA 418
Cdd:pfam15921 372 SGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMA 451
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 419 LVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEINSEEK--QALEAKILELKKTMDEKKS 496
Cdd:pfam15921 452 AIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERaiEATNAEITKLRSRVDLKLQ 531
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 497 TLSLLESQIKKLHNdlyfikksngknndekeslmnkiselnlfiDRSEKELSKAKAVKEDMMIEdnLLKLQVKRARELLY 576
Cdd:pfam15921 532 ELQHLKNEGDHLRN------------------------------VQTECEALKLQMAEKDKVIE--ILRQQIENMTQLVG 579
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 577 SKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAM----------LTSQIRCVEQQRKTMSSEFHERLSKIDKLKN-RYEIL 645
Cdd:pfam15921 580 QHGRTAGAMQVEKAQLEKEINDRRLELQEFKILkdkkdakireLEARVSDLELEKVKLVNAGSERLRAVKDIKQeRDQLL 659
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 646 TVVMLPPEGEEEKTQSYYVIKA--AQEKEELQREGDSLDAKINKAEKEIYALQNTLqvlnscnsnykqsfkKVTPSSDEY 723
Cdd:pfam15921 660 NEVKTSRNELNSLSEDYEVLKRnfRNKSEEMETTTNKLKMQLKSAQSELEQTRNTL---------------KSMEGSDGH 724
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 724 ALKIQLEEQKRTAderyrCKQRQIRELQEDIQSMENTFEVighlANNAKEKLTEKQTlafQLRKETEEQKPKLQRITKQC 803
Cdd:pfam15921 725 AMKVAMGMQKQIT-----AKRGQIDALQSKIQFLEEAMTN----ANKEKHFLKEEKN---KLSQELSTVATEKNKMAGEL 792
|
810
....*....|..
gi 21312922 804 GRLRREIRILKQ 815
Cdd:pfam15921 793 EVLRSQERRLKE 804
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
14-258 |
6.81e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 6.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 14 GFAIPVANQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIeseehfkAIAERE 93
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 94 LGRVKNETQLLEKEMAIIRERKSQMENNIFKTTQklddlkcqmnwdQQALEAWL--EESAHKDSDSLTLQKYSQQDDNKI 171
Cdd:COG4942 85 LAELEKEIAELRAELEAQKEELAELLRALYRLGR------------QPPLALLLspEDFLDAVRRLQYLKYLAPARREQA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 172 RALTLQLEKLT---MEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALAL 248
Cdd:COG4942 153 EELRADLAELAalrAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
|
250
....*....|
gi 21312922 249 SRIKQEAREK 258
Cdd:COG4942 233 EAEAAAAAER 242
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
140-829 |
1.37e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.92 E-value: 1.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 140 QQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKlTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLE 219
Cdd:PTZ00121 1122 KKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED-ARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDAR 1200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 220 RQELIQQWENTIEQMQRRDQEIDNCALALSRIkQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVS-KCRMDYQ 298
Cdd:PTZ00121 1201 KAEAARKAEEERKAEEARKAEDAKKAEAVKKA-EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAiKAEEARK 1279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 299 RHEGNRSQLKDELDTLKTTLNRtssdlqalrKNISKVKKDIfDETLRLQKLKHHNEVVKHKLKMITEKTlsiEEKATNME 378
Cdd:PTZ00121 1280 ADELKKAEEKKKADEAKKAEEK---------KKADEAKKKA-EEAKKADEAKKKAEEAKKKADAAKKKA---EEAKKAAE 1346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 379 DMLKEEEKGLKEVEvqlgivKDVLFKKVQELQNEIAKEKAlvseiegtrSSLKHLNKQLHKLDFETLKQQEIMYSQDFYI 458
Cdd:PTZ00121 1347 AAKAEAEAAADEAE------AAEEKAEAAEKKKEEAKKKA---------DAAKKKAEEKKKADEAKKKAEEDKKKADELK 1411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 459 QQVERRMSRLKGEINSEEKQALEakilELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDE---KESLMNKISE 535
Cdd:PTZ00121 1412 KAAAAKKKADEAKKKAEEKKKAD----EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEakkKAEEAKKADE 1487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 536 LNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEE--RAEEIKVHKAMLTSQ 613
Cdd:PTZ00121 1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADElkKAEELKKAEEKKKAE 1567
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 614 IRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPP-------EGEEEKTQSYYVIKAAQEKEELQREGDSLDAKIN 686
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKmkaeeakKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK 1647
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 687 KAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSSDEYALKIQLEEQ-KRTADERYRCKQRQIRELQE--DIQSMENTFEV 763
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAlKKEAEEAKKAEELKKKEAEEkkKAEELKKAEEE 1727
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21312922 764 IGHLANNAKEKLTEKQTLAFQLRKETEEQKpKLQRITKQCGRLRREIRILKQT-DNETLEEQDIQLR 829
Cdd:PTZ00121 1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKK-KIAHLKKEEEKKAEEIRKEKEAvIEEELDEEDEKRR 1793
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
257-814 |
2.04e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.07 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 257 EKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRmdyqrheGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVK 336
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREEL-------EKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 337 KDIFDETLRLQKLKHHNEVVKHKLKMITEktlsIEEKATN---MEDMLKEEEKGLKEVEVQLGIVKdvlfKKVQELQNEI 413
Cdd:PRK03918 259 EKIRELEERIEELKKEIEELEEKVKELKE----LKEKAEEyikLSEFYEEYLDELREIEKRLSRLE----EEINGIEERI 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 414 AKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMysqdfyiqQVERRMSRLKGEINSEEKQALEAKILELKKT--- 490
Cdd:PRK03918 331 KELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK--------AKKEELERLKKRLTGLTPEKLEKELEELEKAkee 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 491 ----MDEKKSTLSLLESQIKKLHNDLYFIKKSNGK--------NNDEKESLMNKISelnLFIDRSEKELSKAKAVKEDMM 558
Cdd:PRK03918 403 ieeeISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYT---AELKRIEKELKEIEEKERKLR 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 559 IEDNLLKLQVKRAREL--LYSKAEEVLSLEKRKQQLGKDMEERA----EEIKVHKAMLTSQIRCV----------EQQRK 622
Cdd:PRK03918 480 KELRELEKVLKKESELikLKELAEQLKELEEKLKKYNLEELEKKaeeyEKLKEKLIKLKGEIKSLkkelekleelKKKLA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 623 TMSSEFHERLSKIDKLKNRYEILTVVMLPP-EGEEEKTQSYY-----VIKAAQEKEELQREGDSLDAKINKAEKEIYALQ 696
Cdd:PRK03918 560 ELEKKLDELEEELAELLKELEELGFESVEElEERLKELEPFYneyleLKDAEKELEREEKELKKLEEELDKAFEELAETE 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 697 NTLQVLNSCNSNYKQSFKkvtpssdeyalkiqlEEQKRTADERYRCKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLT 776
Cdd:PRK03918 640 KRLEELRKELEELEKKYS---------------EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
|
570 580 590
....*....|....*....|....*....|....*...
gi 21312922 777 EkqtlafqlRKETEEQKPKLQRITKQCGRLRREIRILK 814
Cdd:PRK03918 705 E--------REKAKKELEKLEKALERVEELREKVKKYK 734
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
25-741 |
4.12e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 4.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 25 KILEDQLAKLREEKsnlqDQLHDYEErinsmtshLKNVNQEFLFTQSL--YKARESEIESEEHFKAIAERELGRVKNETQ 102
Cdd:TIGR02169 194 DEKRQQLERLRRER----EKAERYQA--------LLKEKREYEGYELLkeKEALERQKEAIERQLASLEEELEKLTEEIS 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 103 LLEKEMAIIRERKSQM--------ENNIFKTTQKLDDLKCQMNWDQQALEAWL-------EESAHKDSDSLTLQKYSQQD 167
Cdd:TIGR02169 262 ELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEKIGELEAEIASLERSIAEKEreledaeERLAKLEAEIDKLLAEIEEL 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 168 DNKIRALTLQLEKLTMEYNEKRKLLD-------SELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQE 240
Cdd:TIGR02169 342 EREIEEERKRRDKLTEEYAELKEELEdlraeleEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 241 IDNCALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLnR 320
Cdd:TIGR02169 422 LADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-R 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 321 TSSDLQALRKNISKVKKDIFDETL-----------------------RLQKLKHHNEVV-KHKLKMITEKTLSieeKAT- 375
Cdd:TIGR02169 501 ASEERVRGGRAVEEVLKASIQGVHgtvaqlgsvgeryataievaagnRLNNVVVEDDAVaKEAIELLKRRKAG---RATf 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 376 ----NMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLkhLNKQLHKLDFETLKQQEIM 451
Cdd:TIGR02169 578 lplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLM--GKYRMVTLEGELFEKSGAM 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 452 --------YSQDFYIQQVER--RMSRLKGEINsEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGK 521
Cdd:TIGR02169 656 tggsraprGGILFSRSEPAElqRLRERLEGLK-RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 522 NNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMM------------IEDNLLKLQVKRARELLYSKAEEVLSLEKRK 589
Cdd:TIGR02169 735 LKERLEELEEDLSSLEQEIENVKSELKELEARIEELEedlhkleealndLEARLSHSRIPEIQAELSKLEEEVSRIEARL 814
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 590 QQLGKDMEERAEEIKV---HKAMLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSyYVIK 666
Cdd:TIGR02169 815 REIEQKLNRLTLEKEYlekEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK-ERDE 893
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21312922 667 AAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSSDEYALKIQLEEQKRTADERYR 741
Cdd:TIGR02169 894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIR 968
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
388-755 |
4.30e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.92 E-value: 4.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 388 LKEVEVQLGIVKDVLFKKVQELQN-EIAKEKALvseiegtrsSLKHLNKQLHKLDF-ETLKQQEIMYSQdfyIQQVERRM 465
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERlRREREKAE---------RYQALLKEKREYEGyELLKEKEALERQ---KEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 466 SRLKgeinsEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYF-IKKSNGKNNDEKESLMNKISELNLFIDRSE 544
Cdd:TIGR02169 247 ASLE-----EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERSIAEKERELEDAE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 545 KELSKAKAvkedmmiednllklQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVhkamLTSQIRCVEQQRKTM 624
Cdd:TIGR02169 322 ERLAKLEA--------------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELED----LRAELEEVDKEFAET 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 625 SSEFHERLSKIDKLKN-RYEILTVVMLPPEGEEEKTQSYYVIKAA-----QEKEELQREGDSLDAKINKAEKEIYALQNT 698
Cdd:TIGR02169 384 RDELKDYREKLEKLKReINELKRELDRLQEELQRLSEELADLNAAiagieAKINELEEEKEDKALEIKKQEWKLEQLAAD 463
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 21312922 699 LQVLNSCNSNYKQSFKKVTPSSDEYALKI-QLEEQKRTADERYRCKQRQIRELQEDIQ 755
Cdd:TIGR02169 464 LSKYEQELYDLKEEYDRVEKELSKLQRELaEAEAQARASEERVRGGRAVEEVLKASIQ 521
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
16-691 |
4.57e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.92 E-value: 4.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 16 AIPVANQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELG 95
Cdd:TIGR02169 309 SIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 96 RVKNETQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQM---NWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIR 172
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIagiEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 173 ALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIdncALAL---- 248
Cdd:TIGR02169 469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERY---ATAIevaa 545
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 249 -SRIKQEAREKEGVVKEKIKFLEnevennieyERKISVAERkVSKCRMDYQRHEGNRSQLKDELDTLkttlnrtsSDLQA 327
Cdd:TIGR02169 546 gNRLNNVVVEDDAVAKEAIELLK---------RRKAGRATF-LPLNKMRDERRDLSILSEDGVIGFA--------VDLVE 607
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 328 LRKNISKVKKDIFDETLRLQKLKHHNEVVKhKLKMIT------EKTLSI------EEKATNMEDMLKEEEKGLKEVEVQL 395
Cdd:TIGR02169 608 FDPKYEPAFKYVFGDTLVVEDIEAARRLMG-KYRMVTlegelfEKSGAMtggsraPRGGILFSRSEPAELQRLRERLEGL 686
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 396 GIVKDVLFKKVQELQNEIAKEKALVSEIEGtrsSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEI--N 473
Cdd:TIGR02169 687 KRELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELkeL 763
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 474 SEEKQALEAKILELKKTMDEKKStlSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLfidrSEKELSKAKAV 553
Cdd:TIGR02169 764 EARIEELEEDLHKLEEALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL----EKEYLEKEIQE 837
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 554 KEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSEFHERLS 633
Cdd:TIGR02169 838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRK 917
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 21312922 634 KIDKLKNRYEIL-----TVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKE 691
Cdd:TIGR02169 918 RLSELKAKLEALeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQE 980
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
22-314 |
1.43e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 22 QENKILEDQLAKLREEKSNLQDQLHDYEERINSMtshlknvNQEFLFTQSLYKARESEIESEEHFKAIAERELGRvknet 101
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELEEL-------SRQISALRKDLARLEAEVEQLEERIAQLSKELTE----- 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 102 qlLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKL 181
Cdd:TIGR02168 759 --LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 182 TMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRD----------QEIDNCALALSRI 251
Cdd:TIGR02168 837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRseleelseelRELESKRSELRRE 916
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21312922 252 KQEAREKEGVVKEKIKFLENEVENNIE-----YERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTL 314
Cdd:TIGR02168 917 LEELREKLAQLELRLEGLEVRIDNLQErlseeYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
382-704 |
1.76e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.98 E-value: 1.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 382 KEEEKGLKEVEVQLGIVKDVLF---KKVQ--ELQNEIAKE-KALVSEIEGTRSSL-----KHLNKQLHKLDFETLKQQEI 450
Cdd:TIGR02168 175 KETERKLERTRENLDRLEDILNeleRQLKslERQAEKAERyKELKAELRELELALlvlrlEELREELEELQEELKEAEEE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 451 MYSQDFYIQQVERRMSRLKGEINSeekqaLEAKILELKKTMDEKKSTLSLLESQIKKLhndlyfikksngknNDEKESLM 530
Cdd:TIGR02168 255 LEELTAELQELEEKLEELRLEVSE-----LEEEIEELQKELYALANEISRLEQQKQIL--------------RERLANLE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 531 NKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIkvhkAML 610
Cdd:TIGR02168 316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQL 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 611 TSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVI----KAAQEKEELQREGDSLDAKIN 686
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEeeleELQEELERLEEALEELREELE 471
|
330
....*....|....*...
gi 21312922 687 KAEKEIYALQNTLQVLNS 704
Cdd:TIGR02168 472 EAEQALDAAERELAQLQA 489
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
170-433 |
3.11e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 3.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 170 KIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALS 249
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 250 RIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALR 329
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 330 KNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQEL 409
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
250 260
....*....|....*....|....
gi 21312922 410 QNEIAKEKALVSEIEGTRSSLKHL 433
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLL 496
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
95-508 |
6.14e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.44 E-value: 6.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 95 GRVKNETQLLE--KEMAIIRERKSQMENNIFKTTQKLDDLKcqmnwdqqaleawleesahkdsdsltlqkysqqddNKIR 172
Cdd:TIGR02168 664 GSAKTNSSILErrREIEELEEKIEELEEKIAELEKALAELR-----------------------------------KELE 708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 173 ALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIdncalalsrik 252
Cdd:TIGR02168 709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL----------- 777
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 253 QEAREKEGVVKEKIKFLENEVENNieyERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNI 332
Cdd:TIGR02168 778 AEAEAEIEELEAQIEQLKEELKAL---REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI 854
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 333 SKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLgivkdvlfkkvQELQNE 412
Cdd:TIGR02168 855 ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL-----------EELREK 923
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 413 IAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEImySQDFYIQQVERRMSRLKGEINS---------EEKQALEAK 483
Cdd:TIGR02168 924 LAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALEN--KIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKER 1001
|
410 420
....*....|....*....|....*
gi 21312922 484 ILELKKTMDEKKSTLSLLESQIKKL 508
Cdd:TIGR02168 1002 YDFLTAQKEDLTEAKETLEEAIEEI 1026
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
21-566 |
2.31e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.09 E-value: 2.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 21 NQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSlykareseieseehfkaiaerELGRVKNE 100
Cdd:TIGR04523 210 IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKD---------------------EQNKIKKQ 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 101 TQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNwdQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEK 180
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 181 LTMEYNEKRklldselTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEG 260
Cdd:TIGR04523 347 LKKELTNSE-------SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 261 VVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDIF 340
Cdd:TIGR04523 420 EKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 341 DETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGivKDVLFKKVQELQNEIAKEKALV 420
Cdd:TIGR04523 500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK--KENLEKEIDEKNKEIEELKQTQ 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 421 SEIEGTRSSLKHLNKQLHKLDFETLKQQEIMysqdfyiqqvERRMSRLKGEINSEEKQalEAKILELKKTMDEKKSTlsl 500
Cdd:TIGR04523 578 KSLKKKQEEKQELIDQKEKEKKDLIKEIEEK----------EKKISSLEKELEKAKKE--NEKLSSIIKNIKSKKNK--- 642
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21312922 501 LESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKL 566
Cdd:TIGR04523 643 LKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPK 708
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-608 |
2.82e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 2.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 252 KQEAREKEGVVKEKIKFLE---NEVENNIEYERKISVAERKVSKCRMDYQRHEGnrSQLKDELDTLKTTLNRTSSDLQAL 328
Cdd:TIGR02169 172 KEKALEELEEVEENIERLDliiDEKRQQLERLRREREKAERYQALLKEKREYEG--YELLKEKEALERQKEAIERQLASL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 329 RKNISKVKKDIFDETLRL----QKLKHHNEVVKHK----LKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEvqlgivkd 400
Cdd:TIGR02169 250 EEELEKLTEEISELEKRLeeieQLLEELNKKIKDLgeeeQLRVKEKIGELEAEIASLERSIAEKERELEDAE-------- 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 401 vlfKKVQELQNEIAKEKalvSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEINS--EEKQ 478
Cdd:TIGR02169 322 ---ERLAKLEAEIDKLL---AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDyrEKLE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 479 ALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISElnlfidrSEKELSKAKAVKEDMM 558
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK-------QEWKLEQLAADLSKYE 468
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 21312922 559 IEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVHKA 608
Cdd:TIGR02169 469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKA 518
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
143-692 |
4.33e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.62 E-value: 4.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 143 LEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQE 222
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 223 LIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEG 302
Cdd:COG1196 307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 303 NRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLK 382
Cdd:COG1196 387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 383 EEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEimysqDFYIQQVE 462
Cdd:COG1196 467 ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE-----AAYEAALE 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 463 RRMSRLKGEINSEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLyfikKSNGKNNDEKESLMNKISELNLFIDR 542
Cdd:COG1196 542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA----LARGAIGAAVDLVASDLREADARYYV 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 543 SEKELSKAKAVKEDMMIEDNLLKLQVKRARELLY----------SKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAMLTS 612
Cdd:COG1196 618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLegeggsaggsLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 613 QIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREgDSLDAKINKAEKEI 692
Cdd:COG1196 698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-EELERELERLEREI 776
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
23-829 |
5.06e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.37 E-value: 5.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 23 ENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIA-ERELGRVKNET 101
Cdd:TIGR02169 224 EGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEI 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 102 QLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAhkdsdsltlqkysqqddnkirALTLQLEKL 181
Cdd:TIGR02169 304 ASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD---------------------KLTEEYAEL 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 182 TMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGV 261
Cdd:TIGR02169 363 KEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEE 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 262 VKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLnRTSSDLQALRKNISKVKKDIFD 341
Cdd:TIGR02169 443 KEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-RASEERVRGGRAVEEVLKASIQ 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 342 ETL-----------------------RLQKLKHHNEVV-KHKLKMITEKTLSieeKAT-----NMEDMLKEEEKGLKEVE 392
Cdd:TIGR02169 522 GVHgtvaqlgsvgeryataievaagnRLNNVVVEDDAVaKEAIELLKRRKAG---RATflplnKMRDERRDLSILSEDGV 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 393 VQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLkhLNKQLHKLDFETLKQQEIM--------YSQDFYIQQVER- 463
Cdd:TIGR02169 599 IGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLM--GKYRMVTLEGELFEKSGAMtggsraprGGILFSRSEPAEl 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 464 -RMSRLKGEINsEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDR 542
Cdd:TIGR02169 677 qRLRERLEGLK-RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 543 SEKELSKAKAVKEDMmiEDNLLKLQvkrarellyskaEEVLSLEKRkqqlgkDMEERAEEIkvhkamlTSQIRCVEQQRK 622
Cdd:TIGR02169 756 VKSELKELEARIEEL--EEDLHKLE------------EALNDLEAR------LSHSRIPEI-------QAELSKLEEEVS 808
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 623 TMSSEFHERLSKIDKLKNRYEILTvvmlppegeeektqsyyvikaaQEKEELQREGDSLDAKINKAEKEIYALQNTLQVL 702
Cdd:TIGR02169 809 RIEARLREIEQKLNRLTLEKEYLE----------------------KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 703 NSCNSNYKqsfkkvtpsSDEYALKIQLEEQKRTADERyrckQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLA 782
Cdd:TIGR02169 867 EEELEELE---------AALRDLESRLGDLKKERDEL----EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 21312922 783 FQLRKETEEQK------PKLQRITKQCGRLRREIRILKQTDNETLEEQDIQLR 829
Cdd:TIGR02169 934 SEIEDPKGEDEeipeeeLSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLK 986
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
30-292 |
6.14e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.85 E-value: 6.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 30 QLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEflftqsLYKARESEIESEEHFKAIAERELgRVKNETQLLEKEMA 109
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAE------LEELRLELEELELELEEAQAEEY-ELLAELARLEQDIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 110 IIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTMEYNEKR 189
Cdd:COG1196 306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 190 KLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGVVKEKIKFL 269
Cdd:COG1196 386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
|
250 260
....*....|....*....|...
gi 21312922 270 ENEVENNIEYERKISVAERKVSK 292
Cdd:COG1196 466 AELLEEAALLEAALAELLEELAE 488
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
473-692 |
7.44e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 7.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 473 NSEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKA 552
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 553 VKEDMMIEdnlLKLQVKRARELLYSKAEEVLSLEKRK---QQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSEFH 629
Cdd:COG4942 105 ELAELLRA---LYRLGRQPPLALLLSPEDFLDAVRRLqylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 21312922 630 ERLSKIDKLKNRYEILTVVMLPPEGEEEKTQsyyvikaaQEKEELQREGDSLDAKINKAEKEI 692
Cdd:COG4942 182 ELEEERAALEALKAERQKLLARLEKELAELA--------AELAELQQEAEELEALIARLEAEA 236
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
21-565 |
1.46e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.78 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 21 NQENKILEDQLAKLREEKSNLQdqlhdyeerinsmtSHLKNVNQEFLFTQSLYKARESEIEseehfkaiaerelgrvknE 100
Cdd:TIGR04523 165 KKQKEELENELNLLEKEKLNIQ--------------KNIDKIKNKLLKLELLLSNLKKKIQ------------------K 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 101 TQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEK 180
Cdd:TIGR04523 213 NKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQ 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 181 LTMEYNEKRKLLDSELTETLSAQLE-LDKAAQDFRKIHLERQELIQQWENTIEQMQRrdqEIDNCALALSRIKQEAREKE 259
Cdd:TIGR04523 293 LKSEISDLNNQKEQDWNKELKSELKnQEKKLEEIQNQISQNNKIISQLNEQISQLKK---ELTNSESENSEKQRELEEKQ 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 260 GVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDI 339
Cdd:TIGR04523 370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 340 FDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKAL 419
Cdd:TIGR04523 450 SVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 420 VSEIEGTRSSLKHLNKQLHKLDFETLKQQeimysQDFYIQQVERRMSRLKGEINSEEKQALEAKIL--ELKKTMDEKKST 497
Cdd:TIGR04523 530 ESEKKEKESKISDLEDELNKDDFELKKEN-----LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELidQKEKEKKDLIKE 604
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21312922 498 LSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLK 565
Cdd:TIGR04523 605 IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESK 672
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
97-627 |
1.72e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 45.81 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 97 VKNETQLLEKEMAIIRERKSQMENNIfkttqklDDLKCQMNwdqqaleawleeSAHKDSDSLTLQKYSQQDDNKIRALTL 176
Cdd:TIGR01612 1120 IKNLDQKIDHHIKALEEIKKKSENYI-------DEIKAQIN------------DLEDVADKAISNDDPEEIEKKIENIVT 1180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 177 QLEKLTMEYNEKRKLLdSELTETLSAQLELDKA-------AQDFRKIHLER-QELIQQWENTIEQMQRRDQEIDNcalal 248
Cdd:TIGR01612 1181 KIDKKKNIYDEIKKLL-NEIAEIEKDKTSLEEVkginlsyGKNLGKLFLEKiDEEKKKSEHMIKAMEAYIEDLDE----- 1254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 249 srikqearekegvVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDY---QRHEGNRSQLKDELDTLKTTLNRTSsdl 325
Cdd:TIGR01612 1255 -------------IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHiisKKHDENISDIREKSLKIIEDFSEES--- 1318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 326 qalrkNISKVKKDIFDETLRLQKlkhHNEVVKHKLKMITektlsieekatNMEDMLKeeekglkevevqLGIVKDVLfKK 405
Cdd:TIGR01612 1319 -----DINDIKKELQKNLLDAQK---HNSDINLYLNEIA-----------NIYNILK------------LNKIKKII-DE 1366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 406 VQELQNEIAK-EKALVSEIEGTRSSLKHLNKQLhklDFETLKQQEIMYSQDFYIQQVERRMSRLKGEINSEEkqaleAKI 484
Cdd:TIGR01612 1367 VKEYTKEIEEnNKNIKDELDKSEKLIKKIKDDI---NLEECKSKIESTLDDKDIDECIKKIKELKNHILSEE-----SNI 1438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 485 LELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKsNGKNNDEKESLMNkISELNLFIDRSEKelSKAKAVKEDMMIEDN-L 563
Cdd:TIGR01612 1439 DTYFKNADENNENVLLLFKNIEMADNKSQHILK-IKKDNATNDHDFN-INELKEHIDKSKG--CKDEADKNAKAIEKNkE 1514
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21312922 564 LKLQVKRARELLYSKAEEVlSLEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSE 627
Cdd:TIGR01612 1515 LFEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKE 1577
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
20-757 |
1.92e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 20 ANQENKILEDQLAKLREEKSNLQDQLHDYEERI--------NSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAE 91
Cdd:pfam02463 248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEkklqeeelKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 92 RELGRVKNETQLLEKEMAIIRERKSQMENNIFKTTQKLDDL-------------KCQMNWDQQALEAWLEESAHKDSDSL 158
Cdd:pfam02463 328 KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqleeellakkklESERLSSAAKLKEEELELKSEEEKEA 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 159 TLQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRD 238
Cdd:pfam02463 408 QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 239 QEIDNCALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTL 318
Cdd:pfam02463 488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLV 567
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 319 NRTSSDLQALRKNI-----------SKVKKDIFDETLRLQKLKHHNEVVKH-KLKMITEKTLSIEEKATNMEDMLKEEEK 386
Cdd:pfam02463 568 RALTELPLGARKLRllipklklplkSIAVLEIDPILNLAQLDKATLEADEDdKRAKVVEGILKDTELTKLKESAKAKESG 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 387 GLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMS 466
Cdd:pfam02463 648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 467 RLKGEINSEEKQALEAKILELKktMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKE 546
Cdd:pfam02463 728 QEAQDKINEELKLLKQKIDEEE--EEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRA 805
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 547 LSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEER-AEEIKVHKAMLTSQIRCVEQQRKTMS 625
Cdd:pfam02463 806 LEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERlEEEITKEELLQELLLKEEELEEQKLK 885
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 626 SEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLNSC 705
Cdd:pfam02463 886 DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRL 965
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 21312922 706 NSNYKQSFKKVTPSSDEYALKIQLEEQKRTADERYRCKQRQIRELQEDIQSM 757
Cdd:pfam02463 966 LLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
22-343 |
2.43e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 2.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 22 QENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNvnQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNET 101
Cdd:TIGR02169 751 QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 102 QLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKL 181
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 182 TMEYNEKRKLLdSELTETLSAQLELDKaaqdfrkihlerqeliqqwenTIEQMQRRDQEIDNCALALSRIKQEAREKEgv 261
Cdd:TIGR02169 909 EAQIEKKRKRL-SELKAKLEALEEELS---------------------EIEDPKGEDEEIPEEELSLEDVQAELQRVE-- 964
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 262 vkEKIKFLENEVENNIEyerkisvaerkvskcrmDYQRHEGNRSQLKDELDTLKttlnRTSSDLQALRKNISKVKKDIFD 341
Cdd:TIGR02169 965 --EEIRALEPVNMLAIQ-----------------EYEEVLKRLDELKEKRAKLE----EERKAILERIEEYEKKKREVFM 1021
|
..
gi 21312922 342 ET 343
Cdd:TIGR02169 1022 EA 1023
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
28-257 |
2.60e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 28 EDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIA----------------- 90
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAeleaelerldassddla 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 91 --ERELGRVKNETQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMN--------WDQQALEAWLEE---SAHKDSDS 157
Cdd:COG4913 689 alEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEaaedlarlELRALLEERFAAalgDAVERELR 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 158 LTLQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSaqleldkAAQDFRKIH--LERQELI---QQWENtie 232
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLE-------SLPEYLALLdrLEEDGLPeyeERFKE--- 838
|
250 260
....*....|....*....|....*
gi 21312922 233 qmQRRDQEIDNCALALSRIKQEARE 257
Cdd:COG4913 839 --LLNENSIEFVADLLSKLRRAIRE 861
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
458-602 |
2.84e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.85 E-value: 2.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 458 IQQVERRMSRLKGEInseekQALEAKILELKKTMDEKKSTLSLLESQIKKLhndlyfikKSNGKNNDEKEslmNKISELN 537
Cdd:COG2433 408 LTEEEEEIRRLEEQV-----ERLEAEVEELEAELEEKDERIERLERELSEA--------RSEERREIRKD---REISRLD 471
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21312922 538 LFIDRSEKELSkakavKEDMMIEDnlLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEE 602
Cdd:COG2433 472 REIERLERELE-----EERERIEE--LKRKLERLKELWKLEHSGELVPVKVVEKFTKEAIRRLEE 529
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
405-663 |
3.08e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.53 E-value: 3.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 405 KVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQqeimySQDFYIQQVERRMSRLKGEINS--EEKQALEA 482
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIK-----DVEEELEKIEKEIKELEEEISEleNEIKELEQ 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 483 KILELKKtmdekkstLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKE--------LSKAKAVK 554
Cdd:PRK05771 122 EIERLEP--------WGNFDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvvLKELSDEV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 555 EDMMIEDNLLKLQV---KRARELLYSKAEEVLSLEKRKQQLGKDMEE----RAEEIKVHKAMLTSqircvEQQRKTMSSE 627
Cdd:PRK05771 194 EEELKKLGFERLELeeeGTPSELIREIKEELEEIEKERESLLEELKElakkYLEELLALYEYLEI-----ELERAEALSK 268
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 21312922 628 FHERL-----------SKIDKLKNRYEILT-----VVMLPPEGEEEKTQSYY 663
Cdd:PRK05771 269 FLKTDktfaiegwvpeDRVKKLKELIDKATggsayVEFVEPDEEEEEVPTKL 320
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
322-552 |
3.41e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 3.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 322 SSDLQALRKNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEvqlgivkdv 401
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE--------- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 402 lfKKVQELQNEIAKEKALVSEI------EGTRSSLKHLnkqLHKLDFETLKQQEIMYSQdfYIQQVERRMSRLKGEIN-- 473
Cdd:COG4942 90 --KEIAELRAELEAQKEELAELlralyrLGRQPPLALL---LSPEDFLDAVRRLQYLKY--LAPARREQAEELRADLAel 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 21312922 474 SEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKA 552
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
104-607 |
3.70e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 44.33 E-value: 3.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 104 LEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMnwdQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTM 183
Cdd:pfam05483 192 IEKMILAFEELRVQAENARLEMHFKLKEDHEKI---QHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRD 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 184 EYN---EKRKLLDSELTETLSAQLELDKAAQDFrKIHLERQELIQQwenTIEQmqrrdqeidNCALALSRIKQEAREKEG 260
Cdd:pfam05483 269 KANqleEKTKLQDENLKELIEKKDHLTKELEDI-KMSLQRSMSTQK---ALEE---------DLQIATKTICQLTEEKEA 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 261 VVKEKIKFLENEVENNIEYERKISVAERKVskcRMDYQRHEGNRSQLKdeldTLKTTLNRTSSDLQALrkniSKVKKDIF 340
Cdd:pfam05483 336 QMEELNKAKAAHSFVVTEFEATTCSLEELL---RTEQQRLEKNEDQLK----IITMELQKKSSELEEM----TKFKNNKE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 341 DETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVK---DVLFKKVQELQNEIAKEK 417
Cdd:pfam05483 405 VELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKtseEHYLKEVEDLKTELEKEK 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 418 ALVSEIEGTRSSLKHLNKQL-------------HKLDF-ETLKQQEIMYSQDFYIQQVERRMS----------------- 466
Cdd:pfam05483 485 LKNIELTAHCDKLLLENKELtqeasdmtlelkkHQEDIiNCKKQEERMLKQIENLEEKEMNLRdelesvreefiqkgdev 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 467 RLKGEINSEEKQALEAKILELKKTMDEKKSTLSLLESQ-------IKKLHNDLYFIKKSNGKNNDEKESLMNKISELNL- 538
Cdd:pfam05483 565 KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQienknknIEELHQENKALKKKGSAENKQLNAYEIKVNKLELe 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 539 ----------FIDRSEKELSKAKAVKEDMMIE--------DNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERA 600
Cdd:pfam05483 645 lasakqkfeeIIDNYQKEIEDKKISEEKLLEEvekakaiaDEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERD 724
|
....*..
gi 21312922 601 EEIKVHK 607
Cdd:pfam05483 725 SELGLYK 731
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
75-802 |
9.71e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 9.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 75 ARESEIESEEHFKAIAERELGRVKNETQLLEKEMAIIRErksqMENNIfkttQKLDDLKCQMNWDQQALEAWLEESAHKD 154
Cdd:TIGR00606 228 SKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMK----LDNEI----KALKSRKKQMEKDNSELELKMEKVFQGT 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 155 SDSLT-LQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETL----SAQLELDKAAQDFRKIHLERQELIQQWE- 228
Cdd:TIGR00606 300 DEQLNdLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLveqgRLQLQADRHQEHIRARDSLIQSLATRLEl 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 229 NTIEQMQRRDQEIDNC-ALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQL 307
Cdd:TIGR00606 380 DGFERGPFSERQIKNFhTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFV 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 308 KDELDTLKTTLNRTSSDLQALRK---NISKVKKDIFDETLR----------------LQKLKHHNEVVKHKLKMITEKTL 368
Cdd:TIGR00606 460 IKELQQLEGSSDRILELDQELRKaerELSKAEKNSLTETLKkevkslqnekadldrkLRKLDQEMEQLNHHTTTRTQMEM 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 369 SIEEKATNMEDMLKEEEKGLKEVEVQLG------IVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDF 442
Cdd:TIGR00606 540 LTKDKMDKDEQIRKIKSRHSDELTSLLGyfpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEE 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 443 ETLKQQEIMYsQDFYIQQVERRMSRLKGEINSEEKQaleAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFikKSNGKN 522
Cdd:TIGR00606 620 QLSSYEDKLF-DVCGSQDEESDLERLKEEIEKSSKQ---RAMLAGATAVYSQFITQLTDENQSCCPVCQRVF--QTEAEL 693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 523 NDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEE 602
Cdd:TIGR00606 694 QEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETL 773
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 603 IKVHKAMLTSQIRCveQQRKTMSSEFHERLSKIDKlknRYEILTVVMLPPEGEEEKTQsyyvikAAQEKEELQREGDSLD 682
Cdd:TIGR00606 774 LGTIMPEEESAKVC--LTDVTIMERFQMELKDVER---KIAQQAAKLQGSDLDRTVQQ------VNQEKQEKQHELDTVV 842
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 683 AKINKAEKEIYALQNTLQVLNSCNSNYKQSfkkvtpssdeyalKIQLEEQKRTADERYRCKQRQIRELQEDIQSMENTFE 762
Cdd:TIGR00606 843 SKIELNRKLIQDQQEQIQHLKSKTNELKSE-------------KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKE 909
|
730 740 750 760
....*....|....*....|....*....|....*....|
gi 21312922 763 VIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRITKQ 802
Cdd:TIGR00606 910 QDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK 949
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
594-832 |
1.26e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 594 KDMEERAEEIK--------VHKAMLTsqircVEQQRKTMS--SEFHERLSKIDKLKNRYEILtVVMLPPEGEEEKTQSyy 663
Cdd:COG4913 221 PDTFEAADALVehfddlerAHEALED-----AREQIELLEpiRELAERYAAARERLAELEYL-RAALRLWFAQRRLEL-- 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 664 vikAAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLnscnsnykqsfkKVTPSSDEYALKIQLEEQKRTADERYRCK 743
Cdd:COG4913 293 ---LEAELEELRAELARLEAELERLEARLDALREELDEL------------EAQIRGNGGDRLEQLEREIERLERELEER 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 744 QRQIRELQEDIQSME----NTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRITKQCGRLRREIRILKQTDNe 819
Cdd:COG4913 358 ERRRARLEALLAALGlplpASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS- 436
|
250
....*....|...
gi 21312922 820 TLEEQDIQLREII 832
Cdd:COG4913 437 NIPARLLALRDAL 449
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
22-130 |
2.49e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 22 QENKILEDQLAKLREEKSNLQDQLHDYEERInsmtshlknvnqeflftqSLYKARESEIESEEHFKAIAERELGRVKNET 101
Cdd:COG2433 413 EEIRRLEEQVERLEAEVEELEAELEEKDERI------------------ERLERELSEARSEERREIRKDREISRLDREI 474
|
90 100 110
....*....|....*....|....*....|.
gi 21312922 102 QLLEKEMAIIRERKSQMENNI--FKTTQKLD 130
Cdd:COG2433 475 ERLERELEEERERIEELKRKLerLKELWKLE 505
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
330-830 |
2.89e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 41.67 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 330 KNISKVKKDIfDETLRLQKLKHHNEVVKHKLKMITEktLSIEEKATNMEDMLKEEE-KGLKEVEVQLGIVKDVLFKKVQE 408
Cdd:PTZ00121 1230 KKAEEAKKDA-EEAKKAEEERNNEEIRKFEEARMAH--FARRQAAIKAEEARKADElKKAEEKKKADEAKKAEEKKKADE 1306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 409 LQNEiAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDfYIQQVERRMSRLKGEINSEEKQALEAKILELK 488
Cdd:PTZ00121 1307 AKKK-AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA-EAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 489 KTMDEKKSTLSLLE--SQIKKLHNDLYFIKKSNGKNNDEKESL--MNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLL 564
Cdd:PTZ00121 1385 KKAEEKKKADEAKKkaEEDKKKADELKKAAAAKKKADEAKKKAeeKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 565 KLQVKRARELLYSKAEEVLSLEKRKQQlGKDMEERAEEIK--VHKAMLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRY 642
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKK-AEEAKKKADEAKkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAE 1543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 643 EILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKEiyalqntlQVLNSCNSNYKQSFKKVTPSSDE 722
Cdd:PTZ00121 1544 EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA--------RIEEVMKLYEEEKKMKAEEAKKA 1615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 723 YALKIQLEEQKRTADERYRCKQRQIRELQE--DIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRIT 800
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEkkKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695
|
490 500 510
....*....|....*....|....*....|
gi 21312922 801 KQCGRLRREIRILKQTDNETLEEQDIQLRE 830
Cdd:PTZ00121 1696 KEAEEAKKAEELKKKEAEEKKKAEELKKAE 1725
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
175-711 |
3.62e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.58 E-value: 3.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 175 TLQLEKLTMEyNEKRKLLDS--ELTETLSAQL--ELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIdncalalSR 250
Cdd:TIGR01612 719 TVELHLSNIE-NKKNELLDIivEIKKHIHGEInkDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKI-------SE 790
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 251 IKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLN-RTSSDLQALR 329
Cdd:TIGR01612 791 IKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKeKIDSEHEQFA 870
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 330 KNISKVKKDIFDEtlrlqKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEE---------KGLKEVEVQLGIVKD 400
Cdd:TIGR01612 871 ELTNKIKAEISDD-----KLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEyikicentkESIEKFHNKQNILKE 945
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 401 VLFKKVQELQNEIAKEKALVSEIEGT----RSSLKHLNKQLHKLDFETLKQQEIMYSQDFY------------------- 457
Cdd:TIGR01612 946 ILNKNIDTIKESNLIEKSYKDKFDNTlidkINELDKAFKDASLNDYEAKNNELIKYFNDLKanlgknkenmlyhqfdeke 1025
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 458 ---------IQQVERRMSRLKGEIN------SEEKQALEAKILELKKTMDEKKSTLSLLE-SQIK---KLHNDLYFIKKS 518
Cdd:TIGR01612 1026 katndieqkIEDANKNIPNIEIAIHtsiyniIDEIEKEIGKNIELLNKEILEEAEINITNfNEIKeklKHYNFDDFGKEE 1105
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 519 NGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEdnlLKLQVKRARELLYSKA--EEVLSLEKRKQQLGKDM 596
Cdd:TIGR01612 1106 NIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDE---IKAQINDLEDVADKAIsnDDPEEIEKKIENIVTKI 1182
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 597 EERaEEIKVHKAMLTSQIRCVEQQRKTmssefherLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQR 676
Cdd:TIGR01612 1183 DKK-KNIYDEIKKLLNEIAEIEKDKTS--------LEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLD 1253
|
570 580 590
....*....|....*....|....*....|....*
gi 21312922 677 EGDSLDAKINKAEKEIYALQNTLQVLNSCNSNYKQ 711
Cdd:TIGR01612 1254 EIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKD 1288
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
72-838 |
5.33e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.80 E-value: 5.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 72 LYKARESEIESEEHFKAIAERELGRVKNETQLLEKEMA--IIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAwLEE 149
Cdd:TIGR00606 306 LYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTelLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDG-FER 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 150 SAHKD---SDSLTLQKYSQQDDNKIRALTLQ--LEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELi 224
Cdd:TIGR00606 385 GPFSErqiKNFHTLVIERQEDEAKTAAQLCAdlQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKEL- 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 225 QQWENTIEQMQRRDQEIDNCALALSRIKQEA-------------REKEGVVKEKIKFLENEVENNIEYE---RKISVAER 288
Cdd:TIGR00606 464 QQLEGSSDRILELDQELRKAERELSKAEKNSltetlkkevkslqNEKADLDRKLRKLDQEMEQLNHHTTtrtQMEMLTKD 543
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 289 KVSKcrmdYQRHEGNRSQLKDELDTLKTTLNRT---SSDLQALRKNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITE 365
Cdd:TIGR00606 544 KMDK----DEQIRKIKSRHSDELTSLLGYFPNKkqlEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEE 619
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 366 KTLSIEEK------ATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHK 439
Cdd:TIGR00606 620 QLSSYEDKlfdvcgSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISD 699
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 440 LDFETLKQQEIMYSQDFYIQQVERRMSRLKGeinseeKQALEAKILELK-KTMDEKKSTLSLLESQIKKLHNDLYFIKKS 518
Cdd:TIGR00606 700 LQSKLRLAPDKLKSTESELKKKEKRRDEMLG------LAPGRQSIIDLKeKEIPELRNKLQKVNRDIQRLKNDIEEQETL 773
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 519 NGKNNDEKESLMNKISEL----NLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARE-------LLYSKAEEVLSLEK 587
Cdd:TIGR00606 774 LGTIMPEEESAKVCLTDVtimeRFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQekqheldTVVSKIELNRKLIQ 853
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 588 RKQQLGKDMEERAEEIKVHKAMLTS---QIRCVEQQRKTMSSEFHERLSKIDKLKNRyeiltvvMLPPEGEEEKTQsyyv 664
Cdd:TIGR00606 854 DQQEQIQHLKSKTNELKSEKLQIGTnlqRRQQFEEQLVELSTEVQSLIREIKDAKEQ-------DSPLETFLEKDQ---- 922
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 665 ikaaQEKEELqregdsLDAKINKAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSSDEYalKIQLEEQKRTADERYRCKQ 744
Cdd:TIGR00606 923 ----QEKEEL------ISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDY--LKQKETELNTVNAQLEECE 990
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 745 RQIRELQEDIQSMENTFEvighlANNAKEKLTEKQTLAFQLRKETEEQKPKLQRITKQCG------------RLRREIRI 812
Cdd:TIGR00606 991 KHQEKINEDMRLMRQDID-----TQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGqmqvlqmkqehqKLEENIDL 1065
|
810 820
....*....|....*....|....*.
gi 21312922 813 LKQTDNETLEEQDIQLREIIQFHKDI 838
Cdd:TIGR00606 1066 IKRNHVLALGRQKGYEKEIKHFKKEL 1091
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
245-456 |
6.75e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 39.75 E-value: 6.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 245 ALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKIS----VAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNR 320
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLkqlaALERRIAALARRIRALEQELAALEAELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21312922 321 TSSDLQALRKNISKV------------------KKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLK 382
Cdd:COG4942 95 LRAELEAQKEELAELlralyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21312922 383 EEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDF 456
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248
|
|
| |
