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Conserved domains on  [gi|61743938|ref|NP_079324|]
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adhesion G-protein coupled receptor F1 isoform 2 precursor [Homo sapiens]

Protein Classification

SEA domain-containing protein( domain architecture ID 10475853)

SEA (found in Sea urchin sperm protein, Enterokinase, Agrin) domain-containing protein similar to vertebrate interphotoreceptor matrix proteoglycan 1 and human membrane mucins (mucin-12, -16 and -17)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEA super family cl02507
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 154-204 1.36e-04

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


The actual alignment was detected with superfamily member pfam01390:

Pssm-ID: 470595  Cd Length: 100  Bit Score: 39.91  E-value: 1.36e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 61743938   154 GTFKI-NERFTNDLLNSSSAIYSKYANGIEIQLKKAYERI---QGFESVQVTQFR 204
Cdd:pfam01390   5 GSFKItNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNSslrKQYIKSHVLRLR 59
 
Name Accession Description Interval E-value
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 154-204 1.36e-04

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 39.91  E-value: 1.36e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 61743938   154 GTFKI-NERFTNDLLNSSSAIYSKYANGIEIQLKKAYERI---QGFESVQVTQFR 204
Cdd:pfam01390   5 GSFKItNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNSslrKQYIKSHVLRLR 59
 
Name Accession Description Interval E-value
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 154-204 1.36e-04

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 39.91  E-value: 1.36e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 61743938   154 GTFKI-NERFTNDLLNSSSAIYSKYANGIEIQLKKAYERI---QGFESVQVTQFR 204
Cdd:pfam01390   5 GSFKItNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNSslrKQYIKSHVLRLR 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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