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Conserved domains on  [gi|117956393|ref|NP_079145|]
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protein FAM110D [Homo sapiens]

Protein Classification

FAM110_N and FAM110_C domain-containing protein( domain architecture ID 10342682)

FAM110_N and FAM110_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM110_C pfam14160
Centrosome-associated C terminus; This is the C-terminus of a family of proteins that ...
 141-262 8.03e-37

Centrosome-associated C terminus; This is the C-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


:

Pssm-ID: 464094  Cd Length: 113  Bit Score: 126.37  E-value: 8.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117956393  141 DAPEAAGKRALCPTCSLPLSEKERFFNYCGLERALVEVLGAERFSPQSWGADASPQAGTSPPPGSGDASDWTSSDRGvds 220
Cdd:pfam14160   1 RPSLHRSKSDLSSRYSLALSELERFFNYCGLDPEVVEPLGRENFTSAGASSDSSRFRSVSGSSSESGFSRRSGDSSD--- 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 117956393  221 pggaggGGGSEAAGSARDRRPPVSVVERNARVIQWLYGCQRA 262
Cdd:pfam14160  78 ------GTGLDEEELAERVPSGVSVIERNARVIKWLYGCKKA 113
FAM110_N super family cl16669
Centrosome-associated N terminus; This is the N-terminus of a family of proteins that ...
 13-80 1.23e-07

Centrosome-associated N terminus; This is the N-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


The actual alignment was detected with superfamily member pfam14161:

Pssm-ID: 464095  Cd Length: 107  Bit Score: 49.03  E-value: 1.23e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117956393   13 RTPSAVERLEADKAKYVKTHQVIARRQEPAlrgspgpltpHPCNELGPPASPRTPRPVRRGSGRRLPR 80
Cdd:pfam14161  34 KKLSAVERLEADKAKYVKSQEVANTRQEPV----------KPPLLAKPLVSPGLKRGPGLTPGRRGPP 91
 
Name Accession Description Interval E-value
FAM110_C pfam14160
Centrosome-associated C terminus; This is the C-terminus of a family of proteins that ...
 141-262 8.03e-37

Centrosome-associated C terminus; This is the C-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464094  Cd Length: 113  Bit Score: 126.37  E-value: 8.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117956393  141 DAPEAAGKRALCPTCSLPLSEKERFFNYCGLERALVEVLGAERFSPQSWGADASPQAGTSPPPGSGDASDWTSSDRGvds 220
Cdd:pfam14160   1 RPSLHRSKSDLSSRYSLALSELERFFNYCGLDPEVVEPLGRENFTSAGASSDSSRFRSVSGSSSESGFSRRSGDSSD--- 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 117956393  221 pggaggGGGSEAAGSARDRRPPVSVVERNARVIQWLYGCQRA 262
Cdd:pfam14160  78 ------GTGLDEEELAERVPSGVSVIERNARVIKWLYGCKKA 113
FAM110_N pfam14161
Centrosome-associated N terminus; This is the N-terminus of a family of proteins that ...
 13-80 1.23e-07

Centrosome-associated N terminus; This is the N-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464095  Cd Length: 107  Bit Score: 49.03  E-value: 1.23e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117956393   13 RTPSAVERLEADKAKYVKTHQVIARRQEPAlrgspgpltpHPCNELGPPASPRTPRPVRRGSGRRLPR 80
Cdd:pfam14161  34 KKLSAVERLEADKAKYVKSQEVANTRQEPV----------KPPLLAKPLVSPGLKRGPGLTPGRRGPP 91
 
Name Accession Description Interval E-value
FAM110_C pfam14160
Centrosome-associated C terminus; This is the C-terminus of a family of proteins that ...
 141-262 8.03e-37

Centrosome-associated C terminus; This is the C-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464094  Cd Length: 113  Bit Score: 126.37  E-value: 8.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117956393  141 DAPEAAGKRALCPTCSLPLSEKERFFNYCGLERALVEVLGAERFSPQSWGADASPQAGTSPPPGSGDASDWTSSDRGvds 220
Cdd:pfam14160   1 RPSLHRSKSDLSSRYSLALSELERFFNYCGLDPEVVEPLGRENFTSAGASSDSSRFRSVSGSSSESGFSRRSGDSSD--- 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 117956393  221 pggaggGGGSEAAGSARDRRPPVSVVERNARVIQWLYGCQRA 262
Cdd:pfam14160  78 ------GTGLDEEELAERVPSGVSVIERNARVIKWLYGCKKA 113
FAM110_N pfam14161
Centrosome-associated N terminus; This is the N-terminus of a family of proteins that ...
 13-80 1.23e-07

Centrosome-associated N terminus; This is the N-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464095  Cd Length: 107  Bit Score: 49.03  E-value: 1.23e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117956393   13 RTPSAVERLEADKAKYVKTHQVIARRQEPAlrgspgpltpHPCNELGPPASPRTPRPVRRGSGRRLPR 80
Cdd:pfam14161  34 KKLSAVERLEADKAKYVKSQEVANTRQEPV----------KPPLLAKPLVSPGLKRGPGLTPGRRGPP 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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