probable N-acetyltransferase CML1 [Mus musculus]
GNAT family N-acetyltransferase( domain architecture ID 10006981)
GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate
List of domain hits
Name | Accession | Description | Interval | E-value | |||
yhbS | COG3153 | Predicted N-acetyltransferase YhbS [General function prediction only]; |
107-199 | 9.52e-17 | |||
Predicted N-acetyltransferase YhbS [General function prediction only]; : Pssm-ID: 442387 [Multi-domain] Cd Length: 142 Bit Score: 73.97 E-value: 9.52e-17
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Name | Accession | Description | Interval | E-value | |||
yhbS | COG3153 | Predicted N-acetyltransferase YhbS [General function prediction only]; |
107-199 | 9.52e-17 | |||
Predicted N-acetyltransferase YhbS [General function prediction only]; Pssm-ID: 442387 [Multi-domain] Cd Length: 142 Bit Score: 73.97 E-value: 9.52e-17
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Acetyltransf_1 | pfam00583 | Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ... |
91-193 | 4.46e-14 | |||
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 395465 [Multi-domain] Cd Length: 116 Bit Score: 66.00 E-value: 4.46e-14
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NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
109-176 | 1.10e-10 | |||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 55.36 E-value: 1.10e-10
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Name | Accession | Description | Interval | E-value | |||
yhbS | COG3153 | Predicted N-acetyltransferase YhbS [General function prediction only]; |
107-199 | 9.52e-17 | |||
Predicted N-acetyltransferase YhbS [General function prediction only]; Pssm-ID: 442387 [Multi-domain] Cd Length: 142 Bit Score: 73.97 E-value: 9.52e-17
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ArgA | COG1246 | N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ... |
97-198 | 5.28e-16 | |||
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis Pssm-ID: 440859 [Multi-domain] Cd Length: 132 Bit Score: 71.56 E-value: 5.28e-16
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PhnO | COG0454 | N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ... |
78-199 | 7.15e-16 | |||
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only]; Pssm-ID: 440222 [Multi-domain] Cd Length: 136 Bit Score: 71.24 E-value: 7.15e-16
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MnaT | COG1247 | L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism]; |
105-199 | 9.71e-16 | |||
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism]; Pssm-ID: 440860 [Multi-domain] Cd Length: 163 Bit Score: 71.56 E-value: 9.71e-16
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Acetyltransf_1 | pfam00583 | Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ... |
91-193 | 4.46e-14 | |||
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 395465 [Multi-domain] Cd Length: 116 Bit Score: 66.00 E-value: 4.46e-14
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Acetyltransf_7 | pfam13508 | Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. |
106-195 | 2.54e-12 | |||
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. Pssm-ID: 463905 [Multi-domain] Cd Length: 84 Bit Score: 60.55 E-value: 2.54e-12
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RimI | COG0456 | Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ... |
120-198 | 5.11e-12 | |||
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]; Pssm-ID: 440224 [Multi-domain] Cd Length: 92 Bit Score: 60.05 E-value: 5.11e-12
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NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
109-176 | 1.10e-10 | |||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 55.36 E-value: 1.10e-10
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ElaA | COG2153 | Predicted N-acyltransferase, GNAT family [General function prediction only]; |
111-210 | 1.10e-09 | |||
Predicted N-acyltransferase, GNAT family [General function prediction only]; Pssm-ID: 441756 [Multi-domain] Cd Length: 134 Bit Score: 54.81 E-value: 1.10e-09
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Acetyltransf_10 | pfam13673 | Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ... |
109-197 | 3.39e-09 | |||
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 463953 [Multi-domain] Cd Length: 128 Bit Score: 53.04 E-value: 3.39e-09
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COG3393 | COG3393 | Predicted acetyltransferase, GNAT family [General function prediction only]; |
138-204 | 1.91e-08 | |||
Predicted acetyltransferase, GNAT family [General function prediction only]; Pssm-ID: 442620 [Multi-domain] Cd Length: 86 Bit Score: 49.91 E-value: 1.91e-08
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RimL | COG1670 | Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ... |
105-197 | 1.30e-05 | |||
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 441276 [Multi-domain] Cd Length: 173 Bit Score: 44.22 E-value: 1.30e-05
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Acetyltransf_CG | pfam14542 | GCN5-related N-acetyl-transferase; This family of GCN5-related N-acetyl-transferases bind both ... |
144-170 | 3.03e-04 | |||
GCN5-related N-acetyl-transferase; This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule. Pssm-ID: 434030 [Multi-domain] Cd Length: 79 Bit Score: 38.27 E-value: 3.03e-04
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YidJ | COG2388 | Predicted acetyltransferase, GNAT superfamily [General function prediction only]; |
144-170 | 3.52e-04 | |||
Predicted acetyltransferase, GNAT superfamily [General function prediction only]; Pssm-ID: 441953 [Multi-domain] Cd Length: 88 Bit Score: 38.21 E-value: 3.52e-04
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Blast search parameters | ||||
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