|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
94-566 |
2.11e-86 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 273.18 E-value: 2.11e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 94 LSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdps 173
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 174 qeseentaavrrnglhtvptemqflasteakdhpgetevpldlpadsrkEDEYRRNIWKGFLISIPYSASIGGTATLTGT 253
Cdd:COG0471 70 -------------------------------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGT 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 254 APNLILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwRKNKSEIrtnaeDRARAVIREEYQ 333
Cdd:COG0471 101 PPNLIAAGLLEEATGI--PISFFEWMLVGLPVALVGLLLLWLVLYRLL--------PPEIKEV-----PGSKEVIREELA 165
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 334 NLGPIKFAEQAVFILFCMFAILLFTRDPKFIPgwaslfnpgflsDAVTGVAIVTILFFFPsqrpslkwwfdfkapntete 413
Cdd:COG0471 166 ELGPLSRREKIALAIFALTVLLWITGSLHGIP------------IAVVALLGAVLLLLTG-------------------- 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 414 pLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFL 492
Cdd:COG0471 214 -VLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALlPLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLL 292
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 31377715 493 PVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 566
Cdd:COG0471 293 PIAISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
42-558 |
1.14e-69 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 230.16 E-value: 1.14e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 42 LFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVG 121
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 122 VQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqeseentaavrrnglhtvPTEMQFLast 201
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKL-----------------------------DISPSRL--- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 202 eakdhpgetevpldlpadsrkedeyrrniwkgfLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdvvnfGSWFIF 281
Cdd:cd01115 129 ---------------------------------LMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQ------GFSFFE 169
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 282 AFPLMLLFLLAGWLWISFLYGglsfrgwrknkseirtnaedraravireeyqnlgpikfaeqavfILFCMFAILLFTrdp 361
Cdd:cd01115 170 FTPIGLPLLIIGLLYLWFIFR--------------------------------------------LAVLIITIVLLA--- 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 362 kfipgwASLFNPGFLSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAK 441
Cdd:cd01115 203 ------ALAAITGLLPVSVAIAIGAIVLVFGG---------------------VLLTKEDYKSIDWGIIFLFAGGIPLGK 255
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 442 GCEESGLSVWIGGQLHP-LENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFA 520
Cdd:cd01115 256 ALESSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCA 335
|
490 500 510
....*....|....*....|....*....|....*...
gi 31377715 521 FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLL 558
Cdd:cd01115 336 FMLPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVV 373
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
9-566 |
1.12e-68 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 230.34 E-value: 1.12e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 9 KKVWSARRLLVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQ---- 84
Cdd:pfam00939 1 LTLWWKLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKALSWalsg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 85 YFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQParLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL-- 162
Cdd:pfam00939 81 FSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLpp 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 163 -FGqkevrkdpsqeseentaavrrnglhtvptemqflasteakdhpgetevpldlpadSRKEDEYRRNIWKGFLISIPYS 241
Cdd:pfam00939 159 aFG-------------------------------------------------------SDPEKGSERRIGAYLMWTVYQS 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 242 ASIGGTATLTGTAPNLILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGwrknkseirtnae 321
Cdd:pfam00939 184 TSITSAMFLTAMAPNLLLLGLMNSILGV--TITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSV------------- 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 322 DRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIpgwaslfnpgflSDAVTGVAIVTILFFFPsqrpslkw 401
Cdd:pfam00939 249 PDAKAIAKTELKELGPMTFREKALLGLFVLLLLLWIFGGSLNI------------DATTVAIIGLALMLLLR-------- 308
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 402 wfdfkapntetepLLTWKK-AQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPL--ENVPPALAVLLITVVIAFF 478
Cdd:pfam00939 309 -------------ILDWKDiVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSH 375
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 479 TEFASNTATIIIFLPVLAELAIRLRVHP-LYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGV 556
Cdd:pfam00939 376 YLFASATAHTAAMLPIFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGL 455
|
570
....*....|
gi 31377715 557 LLLSLAMNTW 566
Cdd:pfam00939 456 LILLLLGNWW 465
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
29-567 |
7.05e-55 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 192.56 E-value: 7.05e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 29 PVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPI-VLFPFMGIL--PSNKVCPQYFLD-TNFLFLSGLIMASAIE 104
Cdd:TIGR00785 1 PVPDGLNSGAWLLLAIFVAAIVGWILEPLPLPVTALLAIpIIAVLLGVLsaFKFKNALSGFADpTIWLFFGAFILATALV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 105 EWNLHRRIALKILMLVGVQPARL-ILGMMVTTSFLSMWLSNTA-STAMMLPIANAILkslfgqkevrkdpsqeseentaa 182
Cdd:TIGR00785 81 KTGLGKRIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLL----------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 183 vrrnglhtvptemqflasteakdhpgetevpldlPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQ 262
Cdd:TIGR00785 138 ----------------------------------PLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGI 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 263 LKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwrknKSEIRTNaeDRARAVIREEYQNLGPIKFAE 342
Cdd:TIGR00785 184 LSKILGI--QISWGDWFLAGLPLGIILLLLVPLLLYVLF-----------PPELKLK--DEVDLWAKEELEEMGPMSFRE 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 343 QAVFILFcMFAILLFtrdpkfipgwasLFNPGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapntetepLLTWKKAQ 422
Cdd:TIGR00785 249 KALLGIF-LLALLLW------------IFGGSLGINASVVALLAVVLMLFLG--------------------IVTWKDIQ 295
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 423 E-TVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFF-TEFASNTATIIIFLPVLAELA 499
Cdd:TIGR00785 296 KnKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLvGILDGLSPTIAVLVLVVLFYIIlYFFASNTAHTAALVPIFFSVA 375
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 31377715 500 IRLRVHPLYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWA 567
Cdd:TIGR00785 376 SAQGIPLELLALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLWW 444
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
11-162 |
5.61e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 45.77 E-value: 5.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 11 VWSARRLLVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTN 90
Cdd:pfam03600 178 LLIFRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTL 257
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31377715 91 FLFLSGLIMASAIEEWNLHRRIALkiLMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL 162
Cdd:pfam03600 258 LFFAGLFILVGALEKTGLADALAD--ALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAA 327
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
17-162 |
7.97e-05 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 45.27 E-value: 7.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 17 LLVLLFTPLALLPVVFalppkegrclfvILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSG 96
Cdd:cd01115 183 LYLWFIFRLAVLIITI------------VLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGG 250
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31377715 97 LIMASAIEEWNLHRRIALKILMLVGVQPARLILGMM-VTTSFLSMWLSNTASTAMMLPIANAILKSL 162
Cdd:cd01115 251 IPLGKALESSGAAALIAEALISLLGGLPPFAILLLLcLLTLVLTNFISNTATAVLLAPIALSIALSL 317
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
94-566 |
2.11e-86 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 273.18 E-value: 2.11e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 94 LSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdps 173
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 174 qeseentaavrrnglhtvptemqflasteakdhpgetevpldlpadsrkEDEYRRNIWKGFLISIPYSASIGGTATLTGT 253
Cdd:COG0471 70 -------------------------------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGT 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 254 APNLILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwRKNKSEIrtnaeDRARAVIREEYQ 333
Cdd:COG0471 101 PPNLIAAGLLEEATGI--PISFFEWMLVGLPVALVGLLLLWLVLYRLL--------PPEIKEV-----PGSKEVIREELA 165
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 334 NLGPIKFAEQAVFILFCMFAILLFTRDPKFIPgwaslfnpgflsDAVTGVAIVTILFFFPsqrpslkwwfdfkapntete 413
Cdd:COG0471 166 ELGPLSRREKIALAIFALTVLLWITGSLHGIP------------IAVVALLGAVLLLLTG-------------------- 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 414 pLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFL 492
Cdd:COG0471 214 -VLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALlPLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLL 292
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 31377715 493 PVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 566
Cdd:COG0471 293 PIAISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
42-558 |
1.14e-69 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 230.16 E-value: 1.14e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 42 LFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVG 121
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 122 VQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqeseentaavrrnglhtvPTEMQFLast 201
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKL-----------------------------DISPSRL--- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 202 eakdhpgetevpldlpadsrkedeyrrniwkgfLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdvvnfGSWFIF 281
Cdd:cd01115 129 ---------------------------------LMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQ------GFSFFE 169
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 282 AFPLMLLFLLAGWLWISFLYGglsfrgwrknkseirtnaedraravireeyqnlgpikfaeqavfILFCMFAILLFTrdp 361
Cdd:cd01115 170 FTPIGLPLLIIGLLYLWFIFR--------------------------------------------LAVLIITIVLLA--- 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 362 kfipgwASLFNPGFLSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAK 441
Cdd:cd01115 203 ------ALAAITGLLPVSVAIAIGAIVLVFGG---------------------VLLTKEDYKSIDWGIIFLFAGGIPLGK 255
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 442 GCEESGLSVWIGGQLHP-LENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFA 520
Cdd:cd01115 256 ALESSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCA 335
|
490 500 510
....*....|....*....|....*....|....*...
gi 31377715 521 FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLL 558
Cdd:cd01115 336 FMLPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVV 373
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
9-566 |
1.12e-68 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 230.34 E-value: 1.12e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 9 KKVWSARRLLVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQ---- 84
Cdd:pfam00939 1 LTLWWKLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKALSWalsg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 85 YFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQParLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL-- 162
Cdd:pfam00939 81 FSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLpp 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 163 -FGqkevrkdpsqeseentaavrrnglhtvptemqflasteakdhpgetevpldlpadSRKEDEYRRNIWKGFLISIPYS 241
Cdd:pfam00939 159 aFG-------------------------------------------------------SDPEKGSERRIGAYLMWTVYQS 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 242 ASIGGTATLTGTAPNLILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGwrknkseirtnae 321
Cdd:pfam00939 184 TSITSAMFLTAMAPNLLLLGLMNSILGV--TITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSV------------- 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 322 DRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIpgwaslfnpgflSDAVTGVAIVTILFFFPsqrpslkw 401
Cdd:pfam00939 249 PDAKAIAKTELKELGPMTFREKALLGLFVLLLLLWIFGGSLNI------------DATTVAIIGLALMLLLR-------- 308
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 402 wfdfkapntetepLLTWKK-AQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPL--ENVPPALAVLLITVVIAFF 478
Cdd:pfam00939 309 -------------ILDWKDiVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSH 375
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 479 TEFASNTATIIIFLPVLAELAIRLRVHP-LYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGV 556
Cdd:pfam00939 376 YLFASATAHTAAMLPIFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGL 455
|
570
....*....|
gi 31377715 557 LLLSLAMNTW 566
Cdd:pfam00939 456 LILLLLGNWW 465
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
29-567 |
7.05e-55 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 192.56 E-value: 7.05e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 29 PVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPI-VLFPFMGIL--PSNKVCPQYFLD-TNFLFLSGLIMASAIE 104
Cdd:TIGR00785 1 PVPDGLNSGAWLLLAIFVAAIVGWILEPLPLPVTALLAIpIIAVLLGVLsaFKFKNALSGFADpTIWLFFGAFILATALV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 105 EWNLHRRIALKILMLVGVQPARL-ILGMMVTTSFLSMWLSNTA-STAMMLPIANAILkslfgqkevrkdpsqeseentaa 182
Cdd:TIGR00785 81 KTGLGKRIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLL----------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 183 vrrnglhtvptemqflasteakdhpgetevpldlPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQ 262
Cdd:TIGR00785 138 ----------------------------------PLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGI 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 263 LKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwrknKSEIRTNaeDRARAVIREEYQNLGPIKFAE 342
Cdd:TIGR00785 184 LSKILGI--QISWGDWFLAGLPLGIILLLLVPLLLYVLF-----------PPELKLK--DEVDLWAKEELEEMGPMSFRE 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 343 QAVFILFcMFAILLFtrdpkfipgwasLFNPGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapntetepLLTWKKAQ 422
Cdd:TIGR00785 249 KALLGIF-LLALLLW------------IFGGSLGINASVVALLAVVLMLFLG--------------------IVTWKDIQ 295
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 423 E-TVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFF-TEFASNTATIIIFLPVLAELA 499
Cdd:TIGR00785 296 KnKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLvGILDGLSPTIAVLVLVVLFYIIlYFFASNTAHTAALVPIFFSVA 375
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 31377715 500 IRLRVHPLYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWA 567
Cdd:TIGR00785 376 SAQGIPLELLALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLWW 444
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
49-563 |
9.08e-41 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 152.79 E-value: 9.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 49 AVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKIlMLVGVQPARLI 128
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKL-ARASKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 129 LGMMVTTSFLSMWLSNTASTAMMLPIANAILKslfgqkevrkdpsqeseentaavRRNGLHTVPtemqflasteakdhpg 208
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLR-----------------------KLGLSPPVP---------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 209 etevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLILLGQLKsffpqcdvVNFGSWFIFAFPLMLL 288
Cdd:cd00625 121 -------------------------LLLALAFAANIGGAATPIGNPPNLIIASLSG--------LGFLDFLAFMAPPALG 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 289 FLLAGWLWISFLYGGlsfrgwrknksEIRTNAEDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIpgwa 368
Cdd:cd00625 168 LLLLLLGLLYLLFRK-----------KLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLI---- 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 369 slfnpgflsdAVTGVAIVTILFFFpsqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGL 448
Cdd:cd00625 233 ----------ALLGALLLLLLLVR----------------------GLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGL 280
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 449 SVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL-----AIRLRVHPLYLMIPGTVGCSFAFML 523
Cdd:cd00625 281 LEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLappepAWLALALGSTLGGNLTLIGSLANLI 360
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 31377715 524 PVSTPPNSIAfasgHLLVKDMVRTGLLMNLMgVLLLSLAM 563
Cdd:cd00625 361 PLGAAENAGV----GISFGEFLKVGLPLTLL-SLVVSLLY 395
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
49-499 |
1.12e-30 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 122.81 E-value: 1.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 49 AVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLI 128
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 129 LGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslfgqkevrkdpsqeseentaaVRRNGLHTVPtemqflasteakdhpg 208
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLAL------------------------ARRLGLPPSP---------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 209 etevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLILLGQLKsffpqcdvVNFGSWFIFAFPLMLL 288
Cdd:pfam03600 121 -------------------------LLIALAFAANIGGTATPIGDPPNIIIASALG--------LSFGDFGFFMFPPVGV 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 289 FLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIreeyqnlgpikfaeqAVFILFCMFAILLFtrdpkfipgwa 368
Cdd:pfam03600 168 ALLLVGLLPLLLIFRKLLPVRKEEEAELEELRKRAIKDKL---------------LLAISALVLALVIL----------- 221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 369 slfnpGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapnteteplLTWKKAQETVPWNIILLLGGGFAMAKGCEESGL 448
Cdd:pfam03600 222 -----GFLLLSVLALAGALLLLLTGV---------------------LDPEEALKAVDWSTLLFFAGLFILVGALEKTGL 275
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 31377715 449 SVWIGGQLHPLenVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELA 499
Cdd:pfam03600 276 ADALADALGGL--SGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMA 324
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
42-511 |
1.23e-11 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 66.69 E-value: 1.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 42 LFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVG 121
Cdd:COG1055 8 IFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 122 VQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslfgqkevrkdpsqeseentaaVRRNGLHTVPtemqflast 201
Cdd:COG1055 88 GSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAI------------------------ARRLGLNPVP--------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 202 eakdhpgetevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLILLGQLKsffpqcdvVNFGSWFIF 281
Cdd:COG1055 135 --------------------------------FLIAIVFAANIGGAATPIGNPTNIMIASAGG--------LSFLDFLAN 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 282 AFPLMLLFLLAGWLWISFLYGGlSFRGWRKNKSEIRTNAEDRARAVIreeyqnlgpikfaeqAVFILFCMFAILLFTRDP 361
Cdd:COG1055 175 LFPPSLVSLLVTLLVLYLLFRK-ELPAAPDLEDDPKEAIKDRRLLRI---------------SLLVLALLLVGFVLHSFL 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 362 KFIPGWASLFnpgflsdavtgVAIVTILFffpsqrpslkwwfdfkapnTETEPLLTWKKaqetVPWNIILLLGGGFAMAK 441
Cdd:COG1055 239 GLPPALIALL-----------GAAVLLLL-------------------ARVDVREVLKK----VDWSTLLFFIGLFVVVG 284
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 442 GCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMI 511
Cdd:COG1055 285 GLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPEPLWLAL 354
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
414-563 |
5.45e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 61.17 E-value: 5.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 414 PLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLP 493
Cdd:pfam03600 26 GVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIMIP 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31377715 494 VLAELAIRLRVHPLYLMIPGTVGCSFAFML-PVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAM 563
Cdd:pfam03600 106 IVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP 176
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
28-162 |
5.63e-08 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 55.16 E-value: 5.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 28 LPVVFALPPKEGRCLFVILLMAVYWCTEA---LPLSVTALLPIVLFPFMGILPSNKVcpQYFLDTNFLFL--SGLIMASA 102
Cdd:COG0471 164 LAELGPLSRREKIALAIFALTVLLWITGSlhgIPIAVVALLGAVLLLLTGVLTWKDA--YKSIPWGVLLLfgGGLALGAA 241
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31377715 103 IEEWNLHRRIALKIL-MLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL 162
Cdd:COG0471 242 LEKTGLAAWLADALLpLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQAL 302
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
415-539 |
7.40e-08 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 55.13 E-value: 7.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 415 LLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPV 494
Cdd:COG1055 41 VVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPV 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 31377715 495 LAELAIRLRVHPLYLMIpgtvGCSFA-----FMLPVSTPPNSIAFASGHL 539
Cdd:COG1055 121 VLAIARRLGLNPVPFLI----AIVFAaniggAATPIGNPTNIMIASAGGL 166
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
84-520 |
1.87e-07 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 53.79 E-value: 1.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 84 QYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslf 163
Cdd:cd01116 44 WVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRL----- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 164 gqkevrkdpsqeseentaaVRRNGLHTVPtemqflasteakdhpgetevpldlpadsrkedeyrrniwkgFLISIPYSAS 243
Cdd:cd01116 119 -------------------CEVLGLNPVP-----------------------------------------VLISEVIAAN 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 244 IGGTATLTGTAPNLILlgqlksffPQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGglsfRGWRKNKSEIRTNAEDR 323
Cdd:cd01116 139 IGGAATLIGDPPNIMI--------GSAAGLTFNDFLLHMLPSVVLALVVTFILLYFLYR----NILKAREEDVLALAELE 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 324 ARAVIREeyqnlgpIKFAEQAVFILFCMFAILLFTRDPKFIPGWaslfnpgflsdaVTGVAIVTILFFFPsqrpslkwwf 403
Cdd:cd01116 207 PKYPIKD-------KVLLLKSLTILTLVIIGFVLHSPLGVSLGW------------IALLGALLLLLLAD---------- 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 404 dfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFAS 483
Cdd:cd01116 258 -----------KLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILWISALLSAFID 326
|
410 420 430
....*....|....*....|....*....|....*..
gi 31377715 484 NTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFA 520
Cdd:cd01116 327 NIPVTATMIPIVKDLASQLGIPLLPLWWALALGACLG 363
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
11-162 |
5.61e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 45.77 E-value: 5.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 11 VWSARRLLVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTN 90
Cdd:pfam03600 178 LLIFRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTL 257
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31377715 91 FLFLSGLIMASAIEEWNLHRRIALkiLMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL 162
Cdd:pfam03600 258 LFFAGLFILVGALEKTGLADALAD--ALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAA 327
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
17-162 |
7.97e-05 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 45.27 E-value: 7.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 17 LLVLLFTPLALLPVVFalppkegrclfvILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSG 96
Cdd:cd01115 183 LYLWFIFRLAVLIITI------------VLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGG 250
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31377715 97 LIMASAIEEWNLHRRIALKILMLVGVQPARLILGMM-VTTSFLSMWLSNTASTAMMLPIANAILKSL 162
Cdd:cd01115 251 IPLGKALESSGAAALIAEALISLLGGLPPFAILLLLcLLTLVLTNFISNTATAVLLAPIALSIALSL 317
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
240-301 |
3.12e-04 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 43.58 E-value: 3.12e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31377715 240 YSASIGGTATLTGTAPNLILLGQLKSffpQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLY 301
Cdd:COG1055 356 LGATLGGNLTPIGSAANVIVLGIAEK---KGIKISFGEFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
427-539 |
3.56e-03 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 39.94 E-value: 3.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 427 WNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHP 506
Cdd:cd01118 52 WDVTLTLIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKK 131
|
90 100 110
....*....|....*....|....*....|....*..
gi 31377715 507 L----YLMIPGTVGCSFAFMLPVSTPPNSIAFASGHL 539
Cdd:cd01118 132 NrtlpFLYACAFIADAASLPLPISNLVNIVTAGYFGI 168
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
24-155 |
7.46e-03 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 39.15 E-value: 7.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377715 24 PLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYF-LDTNFLFLSGLIMASA 102
Cdd:cd00625 195 LAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVdWGTLLFFAGLFVLVGA 274
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 31377715 103 IEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIA 155
Cdd:cd00625 275 LESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIA 327
|
|
| |
