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Conserved domains on  [gi|258547140|ref|NP_066996|]
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DNA polymerase delta subunit 4 isoform 1 [Homo sapiens]

Protein Classification

DNA polymerase delta subunit 4 family protein( domain architecture ID 5222)

DNA polymerase delta subunit 4 (POLD4) is a small subunit of DNA polymerase delta which has roles in nuclear structure and genomic stability

Gene Ontology:  GO:0000731|GO:0006261|GO:0043625
PubMed:  25501165|32236653

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DNA_pol_delta_4 super family cl04388
DNA polymerase delta, subunit 4;
50-94 8.67e-15

DNA polymerase delta, subunit 4;


The actual alignment was detected with superfamily member pfam04081:

Pssm-ID: 367800  Cd Length: 131  Bit Score: 65.17  E-value: 8.67e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 258547140   50 RQFDLAWQYGPCTGITRLQRWCRAKQMGLEPPPEVWQVLKTHPGD 94
Cdd:pfam04081  80 RYFDMSSKYGPCIGMTRLERWKRAERLGLNPPIEVLAVLLKEEGE 124
 
Name Accession Description Interval E-value
DNA_pol_delta_4 pfam04081
DNA polymerase delta, subunit 4;
50-94 8.67e-15

DNA polymerase delta, subunit 4;


Pssm-ID: 367800  Cd Length: 131  Bit Score: 65.17  E-value: 8.67e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 258547140   50 RQFDLAWQYGPCTGITRLQRWCRAKQMGLEPPPEVWQVLKTHPGD 94
Cdd:pfam04081  80 RYFDMSSKYGPCIGMTRLERWKRAERLGLNPPIEVLAVLLKEEGE 124
 
Name Accession Description Interval E-value
DNA_pol_delta_4 pfam04081
DNA polymerase delta, subunit 4;
50-94 8.67e-15

DNA polymerase delta, subunit 4;


Pssm-ID: 367800  Cd Length: 131  Bit Score: 65.17  E-value: 8.67e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 258547140   50 RQFDLAWQYGPCTGITRLQRWCRAKQMGLEPPPEVWQVLKTHPGD 94
Cdd:pfam04081  80 RYFDMSSKYGPCIGMTRLERWKRAERLGLNPPIEVLAVLLKEEGE 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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