|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
46-983 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 874.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRDRhGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGHHNDLEDVGRDL 125
Cdd:PLN02900 20 FLSFFESK-GHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDLDDVGKDT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKagLDPDLETRDIWLSLgVPASRVLSFGP 205
Cdd:PLN02900 99 YHHTFFEMLGNWSFG-DYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEERVLPFGC 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 206 QENFWEMGDTGPCGPCTEIHYDLAGGVGAPQLV--------ELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVL 277
Cdd:PLN02900 175 KDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVnnddprfiEIWNLVFIQFNREADGSLKPLPAKHVDTGMGLERLASIL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 278 QGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRA 357
Cdd:PLN02900 255 QNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVLRRLLRRA 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 358 VRFSMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGPSDmfpaeva 437
Cdd:PLN02900 335 VRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAAKANG------- 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 438 wSLSLCGD--------LGLPLDMVELMLEEKGVQLDSAGLERlAQEEAQHRARQAE-PVQKQGLWLDVHALGELQRQGVP 508
Cdd:PLN02900 408 -GPVLSGKdafllydtYGFPVDLTELMAEERGVTVDMEGFEA-AMEEARERSRAAHlKAGGGAIELAAEATSWLQKQGVA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 509 PTDDSPKYNySLRPSgsyefgtcEAQVLQLYTEDGtAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVraGQEDVLF 588
Cdd:PLN02900 486 ATDDFLKYD-WLSDH--------EAVVKAILTGGG-FVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLE--GSGGAVV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 589 PVARAQVCGGFILHE-AVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVT 667
Cdd:PLN02900 554 EVSDVQKAGGFVLHIgTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFS 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 668 TQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSL-DEVYPDPVRVVSVGVPVahaldpasqaalqtSV 746
Cdd:PLN02900 634 HGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVfGEKYPDPVRVVSVGGVY--------------SM 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 747 ELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAAterlslgsrDVAEALRLSKDIGR 826
Cdd:PLN02900 700 ELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSA---------LKVEGSDLEKKVAS 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 827 LIEAVETAVMPQWQRRELLATVKMLQRRANTAIRK---LQMGQAAKKTQELLERH-SKGPLIV-----DTVSAESLSvlv 897
Cdd:PLN02900 771 LKSRVDAAVIPAAKKEEIRARVSALQKELRAAQKEaaaLRAKLAVAKATELASKAlSAGKSVLvarldVGVDAAALK--- 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 898 KVVRQLCEQAPSTSVLLLSPQPM-GKVLCACQVAQGAMPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTGS-TTDLEAAL 974
Cdd:PLN02900 848 EAAEKVIAKLGDPAAVVLSSDEEkGKVSLVAAVPPGVVKKgLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRdAEKLDAAL 927
|
....*....
gi 1519312576 975 SIAQTYALS 983
Cdd:PLN02900 928 EKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
46-985 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 775.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRdRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPrsemaGFRRVANSQKCVRAGGHHNDLEDVGRDL 125
Cdd:COG0013 11 FLDFFE-SKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHNDLENVGYTA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDpkagldpDlETRDIWLSL-GVPASRVLSFG 204
Cdd:COG0013 85 RHHTFFEMLGNFSFG-DYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDD-------D-EAYDIWKKEiGVPEERIIRLG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 205 PQENFWEMGDTGPCGPCTEIHYDL--------AGGVGA--PQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLV 274
Cdd:COG0013 156 KKDNFWEMGDTGPCGPCSEIFYDRgpeygggpPGSPGEdgDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLERIA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 275 AVLQGKHSTYDTDLFSPLLNAIQQ--GCRappYlgrvgvADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRR 352
Cdd:COG0013 236 AVLQGVHSNYETDLFRPLIEAAAEltGVK---Y------GADEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRR 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 353 ILRRAVRFSMEI-LKAPpgFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTL--GPS 429
Cdd:COG0013 307 ILRRAVRHGRLLgIKEP--FLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLkaAGG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 430 DMFPAEVAWSLSlcgD-LGLPLDMVELMLEEKGVQLDSAGLERlAQEEAQHRARQA----EPVQKQGLWLDVHALGElqr 504
Cdd:COG0013 385 KVLSGEDAFKLY---DtYGFPLDLTEEIARERGLTVDEEGFEA-AMEEQRERARAAakfsGDAAVDGVWRELLEEGG--- 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 505 qgvpptddspkynyslrPS---GsYEFGTCEAQVLQLYtEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVRA 581
Cdd:COG0013 458 -----------------PTefvG-YDTLEAEAKVLALV-KDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGD 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 582 GqedVLFPVARAQ-VCGGFILHEA-VAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNP 659
Cdd:COG0013 519 G---GVFEVTDTQkPPGGLIVHIGkVEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAP 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 660 EQLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLAlTAQVPGLRSL-DEVYPDpvrvvsvgvpvahaldpas 738
Cdd:COG0013 596 DRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLD-EAKALGAMALfGEKYGD------------------- 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 739 qaalqT---------SVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQA----QQARELGQSLAQEVKAATE 805
Cdd:COG0013 656 -----EvrvvsigdfSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAAleylREQEALLKELAELLKAPPE 730
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 806 rlslgsrdvaealrlskdigRLIEAVEtavmpqwqrrELLATVKMLQRRantaIRKLQMGQAAKKTQELLE--RHSKG-P 882
Cdd:COG0013 731 --------------------ELPERVE----------ALLEELKELEKE----LEQLKAKLASAAADDLLAqaEEIGGvK 776
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 883 LIVDTVSAESLSVLVKVVRQLCEQAPSTSVLLLSPQPmGKVLCACQVAQGAMP-TFTAEAWALAVCSHMGGKAWGSRVVA 961
Cdd:COG0013 777 VLAARVEGVDAKDLRDLADDLKDKLGSGVVVLASVAD-GKVSLVAGVTKDLVKkGLKAGDLVKEVAKIVGGGGGGRPDMA 855
|
970 980
....*....|....*....|....*
gi 1519312576 962 QGTGSTTD-LEAALSIAQTYALSQL 985
Cdd:COG0013 856 QAGGKDPSkLDEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
46-965 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 649.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRDRhGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVANSQKCVRAgghhNDLEDVGRDL 125
Cdd:TIGR00344 6 FLDFFKEK-GHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLENVGRTA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKAGLdpdletrdIWLSLGVPASRVLSFGP 205
Cdd:TIGR00344 76 RHHTLFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYK--------IWEKIGIPADRIIKCDA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 206 QENFWEMGDtGPCGPCTEIHYDLAGG-VGAP-----QLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVLQG 279
Cdd:TIGR00344 147 KDNFWDMGD-GPCGPCTEIYYDFVGGkPGEPleendRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAVLQG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 280 KHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGR--TDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRA 357
Cdd:TIGR00344 226 VPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRveDLRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLIRRA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 358 VRFsMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGpSDMFPAEVA 437
Cdd:TIGR00344 306 LRH-GKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTG-KKELDGEDA 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 438 WSLSlcGDLGLPLDMVELMLEEKGVQLDSAGLERLAQEEaQHRARQAEPVQKQGlwldvhalGELQRqgVPPTDDSPKYN 517
Cdd:TIGR00344 384 FKLY--DTYGFPVELTKEIAEERGLTVDMPGFEALMAEQ-RERSKQNSQFQEQE--------IALVN--VYPATEFLGYD 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 518 YSlrpsgsyefgTCEAQVLQLYtEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVragQEDVLFPVARAQVCG 597
Cdd:TIGR00344 451 DL----------EFEAKVIGLF-DDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLI---ANDGKFRVVDVQKPN 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 598 GFILHEA-VAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQ 676
Cdd:TIGR00344 517 GVVFHFGeVEGGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREE 596
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 677 LRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSLDEVYPDPVRVVSVGVPVAhaldpasqaalqtSVELCCGTHLLR 756
Cdd:TIGR00344 597 LEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFALFGEKYVPGEKVRVVSVGDF-------------SVELCGGTHVRN 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 757 TGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAaterlslgsrdvaealRLSKDIGRLIEAVEtavm 836
Cdd:TIGR00344 664 TGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQEDKLKELAD----------------ILKVTPNELPKKVE---- 723
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 837 pqwqrrELLATVKMLQRRantaIRKLQMGQAAKKTQELLERHSK---GPLIVDTVSAESLSVLVKVVRQLCEQAPSTSVL 913
Cdd:TIGR00344 724 ------RFFEEWKALQKE----LESLKLKIADQKIDELKDKAETingVKVLVEVVDAKDMKSLKTMADRLKSKLGSAIYV 793
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|...
gi 1519312576 914 LLSpQPMGKVLCACQVAQGAMPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTG 965
Cdd:TIGR00344 794 LAS-FAEGKVKLVCGVSNDVLTKkIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
46-624 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 636.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRdRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagFRRVANSQKCVRAGghhnDLEDVGRDL 125
Cdd:pfam01411 6 FLDFFE-KKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAKPP----YNRATNSQKCIRAG----DLENVGRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPkagldpdlETRDIWLSL-GVPASRVLSFG 204
Cdd:pfam01411 77 RHHTFFEMLGNFSFG-DYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERILRFG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 205 PQENFWEMGDTGPCGPCTEIHYD--LAGGVGAPQ---------LVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERL 273
Cdd:pfam01411 148 DKDNFWEMGDTGPCGPCSEIDYDrgEEIGGWDSGgtptadddrFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 274 VAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYlgrvgvaDEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRI 353
Cdd:pfam01411 228 VAVLQDVRSNYDTDVFIPVIELIEEISGARYY-------TVDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 354 LRRAVRFsMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLG-PSDMF 432
Cdd:pfam01411 301 LRRAVRH-AKKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKkGKKTL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 433 PAEVAWSLSlcgD-LGLPLDMVELMLEEKGVQLDSAGLERlAQEEAQHRARQAepVQKQGLWLDVHALGELqrqgvPPTD 511
Cdd:pfam01411 380 PGEDAFKLY---DtYGFPVDLTKEIAEERGLKVDMPGFEY-AMVEQRERSKQA--VKEKGEKLDVSALKEL-----PATT 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 512 DSPKYNYSLrpsgsyefgtCEAQVLQLYTeDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVragQEDVLFPVA 591
Cdd:pfam01411 449 EFLGYDDLE----------SEAKILALPK-DGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYII---GDGGEFRVT 514
|
570 580 590
....*....|....*....|....*....|....
gi 1519312576 592 RAQVCGGFILHEAVAPE-CLRLGDQVQLHVDEAW 624
Cdd:pfam01411 515 DVQKYGGVVVHKGKLESgKLKVGDKVIAVIDEDR 548
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
46-280 |
7.51e-113 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 347.04 E-value: 7.51e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRdRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVANSQKCVRAGGHHNdledVGRDL 125
Cdd:cd00673 8 FLSFFE-KKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN----VGKTG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDpkagldpDLETRDIWLSLGVPASRVLSFGP 205
Cdd:cd00673 78 RHHTFFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRIERIGF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 206 QENFWEMGDTGPCGPCTEIHYDLAGGVGA--------PQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVL 277
Cdd:cd00673 150 KDNFWEMGGNGPCGPCSEIFYDRGEERDAaslpneddDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLVWVL 229
|
...
gi 1519312576 278 QGK 280
Cdd:cd00673 230 QGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
745-778 |
4.62e-06 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 44.30 E-value: 4.62e-06
10 20 30
....*....|....*....|....*....|....
gi 1519312576 745 SVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRL 778
Cdd:smart00863 10 SVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
46-983 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 874.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRDRhGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGHHNDLEDVGRDL 125
Cdd:PLN02900 20 FLSFFESK-GHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDLDDVGKDT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKagLDPDLETRDIWLSLgVPASRVLSFGP 205
Cdd:PLN02900 99 YHHTFFEMLGNWSFG-DYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEERVLPFGC 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 206 QENFWEMGDTGPCGPCTEIHYDLAGGVGAPQLV--------ELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVL 277
Cdd:PLN02900 175 KDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVnnddprfiEIWNLVFIQFNREADGSLKPLPAKHVDTGMGLERLASIL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 278 QGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRA 357
Cdd:PLN02900 255 QNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVLRRLLRRA 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 358 VRFSMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGPSDmfpaeva 437
Cdd:PLN02900 335 VRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAAKANG------- 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 438 wSLSLCGD--------LGLPLDMVELMLEEKGVQLDSAGLERlAQEEAQHRARQAE-PVQKQGLWLDVHALGELQRQGVP 508
Cdd:PLN02900 408 -GPVLSGKdafllydtYGFPVDLTELMAEERGVTVDMEGFEA-AMEEARERSRAAHlKAGGGAIELAAEATSWLQKQGVA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 509 PTDDSPKYNySLRPSgsyefgtcEAQVLQLYTEDGtAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVraGQEDVLF 588
Cdd:PLN02900 486 ATDDFLKYD-WLSDH--------EAVVKAILTGGG-FVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLE--GSGGAVV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 589 PVARAQVCGGFILHE-AVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVT 667
Cdd:PLN02900 554 EVSDVQKAGGFVLHIgTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFS 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 668 TQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSL-DEVYPDPVRVVSVGVPVahaldpasqaalqtSV 746
Cdd:PLN02900 634 HGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVfGEKYPDPVRVVSVGGVY--------------SM 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 747 ELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAAterlslgsrDVAEALRLSKDIGR 826
Cdd:PLN02900 700 ELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSA---------LKVEGSDLEKKVAS 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 827 LIEAVETAVMPQWQRRELLATVKMLQRRANTAIRK---LQMGQAAKKTQELLERH-SKGPLIV-----DTVSAESLSvlv 897
Cdd:PLN02900 771 LKSRVDAAVIPAAKKEEIRARVSALQKELRAAQKEaaaLRAKLAVAKATELASKAlSAGKSVLvarldVGVDAAALK--- 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 898 KVVRQLCEQAPSTSVLLLSPQPM-GKVLCACQVAQGAMPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTGS-TTDLEAAL 974
Cdd:PLN02900 848 EAAEKVIAKLGDPAAVVLSSDEEkGKVSLVAAVPPGVVKKgLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRdAEKLDAAL 927
|
....*....
gi 1519312576 975 SIAQTYALS 983
Cdd:PLN02900 928 EKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
46-985 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 775.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRdRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPrsemaGFRRVANSQKCVRAGGHHNDLEDVGRDL 125
Cdd:COG0013 11 FLDFFE-SKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHNDLENVGYTA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDpkagldpDlETRDIWLSL-GVPASRVLSFG 204
Cdd:COG0013 85 RHHTFFEMLGNFSFG-DYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDD-------D-EAYDIWKKEiGVPEERIIRLG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 205 PQENFWEMGDTGPCGPCTEIHYDL--------AGGVGA--PQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLV 274
Cdd:COG0013 156 KKDNFWEMGDTGPCGPCSEIFYDRgpeygggpPGSPGEdgDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLERIA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 275 AVLQGKHSTYDTDLFSPLLNAIQQ--GCRappYlgrvgvADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRR 352
Cdd:COG0013 236 AVLQGVHSNYETDLFRPLIEAAAEltGVK---Y------GADEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRR 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 353 ILRRAVRFSMEI-LKAPpgFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTL--GPS 429
Cdd:COG0013 307 ILRRAVRHGRLLgIKEP--FLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLkaAGG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 430 DMFPAEVAWSLSlcgD-LGLPLDMVELMLEEKGVQLDSAGLERlAQEEAQHRARQA----EPVQKQGLWLDVHALGElqr 504
Cdd:COG0013 385 KVLSGEDAFKLY---DtYGFPLDLTEEIARERGLTVDEEGFEA-AMEEQRERARAAakfsGDAAVDGVWRELLEEGG--- 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 505 qgvpptddspkynyslrPS---GsYEFGTCEAQVLQLYtEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVRA 581
Cdd:COG0013 458 -----------------PTefvG-YDTLEAEAKVLALV-KDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGD 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 582 GqedVLFPVARAQ-VCGGFILHEA-VAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNP 659
Cdd:COG0013 519 G---GVFEVTDTQkPPGGLIVHIGkVEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAP 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 660 EQLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLAlTAQVPGLRSL-DEVYPDpvrvvsvgvpvahaldpas 738
Cdd:COG0013 596 DRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLD-EAKALGAMALfGEKYGD------------------- 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 739 qaalqT---------SVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQA----QQARELGQSLAQEVKAATE 805
Cdd:COG0013 656 -----EvrvvsigdfSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAAleylREQEALLKELAELLKAPPE 730
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 806 rlslgsrdvaealrlskdigRLIEAVEtavmpqwqrrELLATVKMLQRRantaIRKLQMGQAAKKTQELLE--RHSKG-P 882
Cdd:COG0013 731 --------------------ELPERVE----------ALLEELKELEKE----LEQLKAKLASAAADDLLAqaEEIGGvK 776
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 883 LIVDTVSAESLSVLVKVVRQLCEQAPSTSVLLLSPQPmGKVLCACQVAQGAMP-TFTAEAWALAVCSHMGGKAWGSRVVA 961
Cdd:COG0013 777 VLAARVEGVDAKDLRDLADDLKDKLGSGVVVLASVAD-GKVSLVAGVTKDLVKkGLKAGDLVKEVAKIVGGGGGGRPDMA 855
|
970 980
....*....|....*....|....*
gi 1519312576 962 QGTGSTTD-LEAALSIAQTYALSQL 985
Cdd:COG0013 856 QAGGKDPSkLDEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
46-965 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 649.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRDRhGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVANSQKCVRAgghhNDLEDVGRDL 125
Cdd:TIGR00344 6 FLDFFKEK-GHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLENVGRTA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKAGLdpdletrdIWLSLGVPASRVLSFGP 205
Cdd:TIGR00344 76 RHHTLFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYK--------IWEKIGIPADRIIKCDA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 206 QENFWEMGDtGPCGPCTEIHYDLAGG-VGAP-----QLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVLQG 279
Cdd:TIGR00344 147 KDNFWDMGD-GPCGPCTEIYYDFVGGkPGEPleendRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAVLQG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 280 KHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGR--TDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRA 357
Cdd:TIGR00344 226 VPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRveDLRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLIRRA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 358 VRFsMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGpSDMFPAEVA 437
Cdd:TIGR00344 306 LRH-GKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTG-KKELDGEDA 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 438 WSLSlcGDLGLPLDMVELMLEEKGVQLDSAGLERLAQEEaQHRARQAEPVQKQGlwldvhalGELQRqgVPPTDDSPKYN 517
Cdd:TIGR00344 384 FKLY--DTYGFPVELTKEIAEERGLTVDMPGFEALMAEQ-RERSKQNSQFQEQE--------IALVN--VYPATEFLGYD 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 518 YSlrpsgsyefgTCEAQVLQLYtEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVragQEDVLFPVARAQVCG 597
Cdd:TIGR00344 451 DL----------EFEAKVIGLF-DDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLI---ANDGKFRVVDVQKPN 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 598 GFILHEA-VAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQ 676
Cdd:TIGR00344 517 GVVFHFGeVEGGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREE 596
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 677 LRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSLDEVYPDPVRVVSVGVPVAhaldpasqaalqtSVELCCGTHLLR 756
Cdd:TIGR00344 597 LEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFALFGEKYVPGEKVRVVSVGDF-------------SVELCGGTHVRN 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 757 TGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAaterlslgsrdvaealRLSKDIGRLIEAVEtavm 836
Cdd:TIGR00344 664 TGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQEDKLKELAD----------------ILKVTPNELPKKVE---- 723
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 837 pqwqrrELLATVKMLQRRantaIRKLQMGQAAKKTQELLERHSK---GPLIVDTVSAESLSVLVKVVRQLCEQAPSTSVL 913
Cdd:TIGR00344 724 ------RFFEEWKALQKE----LESLKLKIADQKIDELKDKAETingVKVLVEVVDAKDMKSLKTMADRLKSKLGSAIYV 793
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|...
gi 1519312576 914 LLSpQPMGKVLCACQVAQGAMPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTG 965
Cdd:TIGR00344 794 LAS-FAEGKVKLVCGVSNDVLTKkIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
46-624 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 636.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRdRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagFRRVANSQKCVRAGghhnDLEDVGRDL 125
Cdd:pfam01411 6 FLDFFE-KKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAKPP----YNRATNSQKCIRAG----DLENVGRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPkagldpdlETRDIWLSL-GVPASRVLSFG 204
Cdd:pfam01411 77 RHHTFFEMLGNFSFG-DYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERILRFG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 205 PQENFWEMGDTGPCGPCTEIHYD--LAGGVGAPQ---------LVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERL 273
Cdd:pfam01411 148 DKDNFWEMGDTGPCGPCSEIDYDrgEEIGGWDSGgtptadddrFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 274 VAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYlgrvgvaDEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRI 353
Cdd:pfam01411 228 VAVLQDVRSNYDTDVFIPVIELIEEISGARYY-------TVDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 354 LRRAVRFsMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLG-PSDMF 432
Cdd:pfam01411 301 LRRAVRH-AKKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKkGKKTL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 433 PAEVAWSLSlcgD-LGLPLDMVELMLEEKGVQLDSAGLERlAQEEAQHRARQAepVQKQGLWLDVHALGELqrqgvPPTD 511
Cdd:pfam01411 380 PGEDAFKLY---DtYGFPVDLTKEIAEERGLKVDMPGFEY-AMVEQRERSKQA--VKEKGEKLDVSALKEL-----PATT 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 512 DSPKYNYSLrpsgsyefgtCEAQVLQLYTeDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVragQEDVLFPVA 591
Cdd:pfam01411 449 EFLGYDDLE----------SEAKILALPK-DGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYII---GDGGEFRVT 514
|
570 580 590
....*....|....*....|....*....|....
gi 1519312576 592 RAQVCGGFILHEAVAPE-CLRLGDQVQLHVDEAW 624
Cdd:pfam01411 515 DVQKYGGVVVHKGKLESgKLKVGDKVIAVIDEDR 548
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
46-280 |
7.51e-113 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 347.04 E-value: 7.51e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRdRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVANSQKCVRAGGHHNdledVGRDL 125
Cdd:cd00673 8 FLSFFE-KKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN----VGKTG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDpkagldpDLETRDIWLSLGVPASRVLSFGP 205
Cdd:cd00673 78 RHHTFFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRIERIGF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 206 QENFWEMGDTGPCGPCTEIHYDLAGGVGA--------PQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVL 277
Cdd:cd00673 150 KDNFWEMGGNGPCGPCSEIFYDRGEERDAaslpneddDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERLVWVL 229
|
...
gi 1519312576 278 QGK 280
Cdd:cd00673 230 QGV 232
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
46-784 |
2.20e-108 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 348.69 E-value: 2.20e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 46 FLNFFRDRhGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPrsemAGFRRVaNSQKCVRAGghhnDLEDVGrDL 125
Cdd:PRK01584 10 YIDFFKSK-GHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHP----SGTRLV-DVQKCLRTG----DIDEVG-DL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 126 SHHTFFEMLGNWAFGgEYFKEEACNMAWELLT--QVYGIPEERLWISYFDGDPKAgldP-DLETRDIWLSLGVPASRVLS 202
Cdd:PRK01584 79 SHLTFFEMLGNWSLG-AYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEEI---PrDEETASVWESLGIPKDRIFY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 203 FGPQENFW-EMGDTGPCGPCTEIHYDLAG---------GVGAPQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLER 272
Cdd:PRK01584 155 LSREHNWWgPVGETGPCGPDTEIFVDTGKpkcsvncrpTCSCGKYFEIWNNVFMQYNKDEDGNYEELKRKCVDTGMGIER 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 273 LVAVLQGKHSTYDTDLFSPLLNAIQQGCrappylGRVgVADEGRTDTAYRVVADHIRTLSVCISD--GIFPGMSGPPLVL 350
Cdd:PRK01584 235 TIAFLQGKSSVYDTEAFTPIIKRIEKIS------GKI-YGQNEEDDRSIRIIADHIRAACFILGDpfVVLPSNVGQGYVL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 351 RRILRRAVRFSMEiLKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGPSD 430
Cdd:PRK01584 308 RRLIRRSIRHAKK-LGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLGSSK 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 431 MFPAEVAWSLSlcGDLGLPLDMVELMLEEKGVQLDSAGLErlaQEEAQHRarqaepvqkqglwldvhalgELQRQGvppt 510
Cdd:PRK01584 387 IIPGDIAFKLY--DTYGFPYEITEELASEYGFTVDREGFD---EHFKKHQ--------------------KVSKKG---- 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 511 ddspkynyslrpsgsyefgtceaqvlqlytedgtavasvgkgqrcgllldrtnfyaeqggqasdrgylvragqEDVLFPv 590
Cdd:PRK01584 438 -------------------------------------------------------------------------ADKVFK- 443
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 591 araqvcGGfilheavapeclrLGDqvqlHVDEAWRLgcmakHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQT 670
Cdd:PRK01584 444 ------GG-------------LAD----HSYETTKL-----HTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPE 495
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 671 PLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSLDEVYPDpvrvvsvgVPVAHALDpasqaalQTSVELCC 750
Cdd:PRK01584 496 KMTDDEIKKVEDIVNLQIKNDLSVKKEVMSLEEAREKGAMALFGEKYED--------IVKVYEID-------GFSKEVCG 560
|
730 740 750
....*....|....*....|....*....|....
gi 1519312576 751 GTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGE 784
Cdd:PRK01584 561 GPHVENTGELGTFKIQKEQSSSSGVRRIRAILID 594
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
530-778 |
7.31e-30 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 118.76 E-value: 7.31e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 530 TCEAQVLQLyTEDGtavasvgkgqrcGLLLDRTNFYAEQGGQASDRGYLVRAGQEdvlFPVARAQVCGGFILHEAVAPEC 609
Cdd:COG2872 14 EFEATVTAV-TEEG------------GVVLDRTAFYPTGGGQPGDTGTLVWDGKE---IRVVDVRKEDGEIVHVLEGAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 610 LRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEqqGSHLNPEQLRLDVTTQTPlTPEQLRAVENTVQEAVG 689
Cdd:COG2872 78 PEVGDEVTGEIDWERRYRHMRLHTALHLLSAVVYREYGAPVT--GGQIGEDRARIDFDLPEF-DEEDLEEIEAEANELIA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 690 QDEAVYMEEVPLALTAQVPGLRSLDEVYPdpvrvvsvgvpvahaldPASQAALQTsVEL-------CCGTHLLRTGAVGD 762
Cdd:COG2872 155 ADLPVRIYWITREELEAIPGLVRTMSVLP-----------------PPGVGRVRI-VEIggvdlqpCGGTHVANTGEIGR 216
|
250
....*....|....*.
gi 1519312576 763 LVIIGDRQLSKGTTRL 778
Cdd:COG2872 217 IKITKIEKKGKGNRRV 232
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
554-778 |
1.73e-10 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 62.02 E-value: 1.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 554 RCGLLLDRTNFYAEQGGQASDRGYLVRAGQeDVLFPVARAQVCGGFILH----EAVAPEC---LRLGDQVQLHVDEAWRL 626
Cdd:PLN02961 2 RIALVLDRTIFHPQGGGQPSDTGRIVISGG-DTKFSVQDVRRKDGVVYHygvfEGSNPESaspFEAGDEVTVTVDESRRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 627 GCMAKHTATHLLNWALRQT-LGPGTEQQGSHLnPEQLRLDVTTQTPltPEQLRAVENTVQEA----VGQDEAVYMEEVPL 701
Cdd:PLN02961 81 LHSRLHSAGHLLDVCMARVgLGPLEPGKGYHF-PDGPFVEYKGKIP--QGELDSKQDELEAEanelIAEGGKVSAAVLPY 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1519312576 702 ALTAQVPGlRSLDEvYPDPVRVVSVGVPVAHALDPasqaalqtsvelCCGTHLLRTGAVGDLVIIGDRqLSKGTTRL 778
Cdd:PLN02961 158 DEAAELCG-GSLPD-YIAKDSTPRIVKIGDSPGCP------------CGGTHVADVSEITSVKVTQIR-VKKGVTRV 219
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
745-778 |
4.62e-06 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 44.30 E-value: 4.62e-06
10 20 30
....*....|....*....|....*....|....
gi 1519312576 745 SVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRL 778
Cdd:smart00863 10 SVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| class_II_aaRS-like_core |
cd00768 |
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ... |
97-273 |
5.22e-06 |
|
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain] Cd Length: 211 Bit Score: 48.65 E-value: 5.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 97 AGFRRVANSQKCVRAGGHHndledvgRDLSHHTFFEMLGNWAFGGEYFKEEacnmawelltqvygipEERLWISYfdgdp 176
Cdd:cd00768 73 KLPLRLAEIGPAFRNEGGR-------RGLRRVREFTQLEGEVFGEDGEEAS----------------EFEELIEL----- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519312576 177 kagldpdleTRDIWLSLGVPASRVLSFGPQENFWEmgdtGPCGPCTEIHYDLAGGVGapqlVELWNLVFMQHN--READG 254
Cdd:cd00768 125 ---------TEELLRALGIKLDIVFVEKTPGEFSP----GGAGPGFEIEVDHPEGRG----LEIGSGGYRQDEqaRAADL 187
|
170 180
....*....|....*....|....
gi 1519312576 255 SLQPLPQR-----HVDTGMGLERL 273
Cdd:cd00768 188 YFLDEALEyryppTIGFGLGLERL 211
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
745-778 |
2.02e-04 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 39.74 E-value: 2.02e-04
10 20 30
....*....|....*....|....*....|....
gi 1519312576 745 SVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRL 778
Cdd:pfam07973 10 DVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| |
