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Conserved domains on  [gi|9507107|ref|NP_062102|]
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solute carrier family 12 member 4 [Rattus norvegicus]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
42-1085 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1354.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107      42 NHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGT 120
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     121 LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGA 200
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     201 VGLCFYLGTTFAAAMYILGAIEILLTyiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 280
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     281 LACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 360
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     361 nvtEIPGIPGAAAGvlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNR 440
Cdd:TIGR00930  271 ---FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANI 302
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     441 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTL 499
Cdd:TIGR00930  303 SGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSL 382
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     500 AWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVA 578
Cdd:TIGR00930  383 VSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIA 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     579 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAE 658
Cdd:TIGR00930  463 PIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPD 542
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     659 KEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 738
Cdd:TIGR00930  543 VNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLEC 618
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     739 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCT 818
Cdd:TIGR00930  619 VKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDA 697
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     819 TAAHLALLVPKNIAFYPSNH--------------------------------------ERYLEGHIDVWWIVHDGGMLML 860
Cdd:TIGR00930  698 FDAHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLL 777
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     861 LPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMR 940
Cdd:TIGR00930  778 LPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFR 852
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     941 LTKTERDREAqlvKDRHsalrleslysdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfRELvhikpdQSNVRRMH 1020
Cdd:TIGR00930  853 LHKTEKDREA---KDPK------------------------MTWTKPWKITD-----------AEL------QSNVRKSY 888
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 9507107    1021 TAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1085
Cdd:TIGR00930  889 RQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
42-1085 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1354.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107      42 NHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGT 120
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     121 LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGA 200
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     201 VGLCFYLGTTFAAAMYILGAIEILLTyiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 280
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     281 LACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 360
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     361 nvtEIPGIPGAAAGvlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNR 440
Cdd:TIGR00930  271 ---FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANI 302
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     441 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTL 499
Cdd:TIGR00930  303 SGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSL 382
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     500 AWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVA 578
Cdd:TIGR00930  383 VSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIA 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     579 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAE 658
Cdd:TIGR00930  463 PIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPD 542
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     659 KEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 738
Cdd:TIGR00930  543 VNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLEC 618
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     739 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCT 818
Cdd:TIGR00930  619 VKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDA 697
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     819 TAAHLALLVPKNIAFYPSNH--------------------------------------ERYLEGHIDVWWIVHDGGMLML 860
Cdd:TIGR00930  698 FDAHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLL 777
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     861 LPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMR 940
Cdd:TIGR00930  778 LPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFR 852
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     941 LTKTERDREAqlvKDRHsalrleslysdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfRELvhikpdQSNVRRMH 1020
Cdd:TIGR00930  853 LHKTEKDREA---KDPK------------------------MTWTKPWKITD-----------AEL------QSNVRKSY 888
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 9507107    1021 TAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1085
Cdd:TIGR00930  889 RQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
123-695 5.11e-51

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 187.53  E-value: 5.11e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     123 GVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVpAGGSYFMISRSLGPEFGGAVG 202
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     203 L--CFYLGTTFAAAmyiLGAIEILLTYIAPPAAIFYPSGThdmssatlnnmrvyGTIFLTFMTLVVFVGVKYVNKFASLF 280
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDIPYLWVW--------------GAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     281 LACVIISILSIYVGGIKSAFDPpvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 360
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIILLSGG---------------------------------------------------------- 164
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     361 nvteipgipGAAAGVLQENLWSAYLEKgevvekhglpstdtlglkeslslYVVADIATSFTVLVGIFFPSVTGIMAGSNR 440
Cdd:pfam00324  165 ---------NPNDGAIFRYLGDNGGKN-----------------------NFPPGFGKGFISVFVIAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     441 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVV------GTLAWPSpwVIVVGSFFS 514
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTA 290
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     515 TCGAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHGKANGEPTWALLLTALIAELGILIASLdmVAPILSMFFLMCYLFVNL 594
Cdd:pfam00324  291 ALSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGL 366
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     595 ACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR 674
Cdd:pfam00324  367 IVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVL 446
                          570       580
                   ....*....|....*....|.
gi 9507107     675 YALLRLEEGPPHTKNWRPQLL 695
Cdd:pfam00324  447 LFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
131-655 2.50e-34

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 137.34  E-value: 2.50e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   131 NIFGVILFLRLTWMVGTAGvLQALLIVLICCCCTLLTAISMSAIATNgvVP-AGGSYFMISRSLGPEFGGAVGLCFYLGT 209
Cdd:COG0531   25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLLSY 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   210 TFAAAMYILGAIEILltyiappaAIFYPSGTHDmssatlnnmrVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISIL 289
Cdd:COG0531  102 VLAVAAVAVAFGGYL--------SSLFPAGGSV----------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   290 SIYVGGIksafdppvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdPYFLLNNVTEIPGIP 369
Cdd:COG0531  164 LFIVVGL----------------------------------------------------------FAFDPANFTPFLPAG 185
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   370 GAAAGVlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFpSVTGIMAGSNRSGDLRDAQK 449
Cdd:COG0531  186 GGLSGV--------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   450 SIPVGTILAIVTTSLVYFSSVILFGacieGVVLRDKYGDGVSRNLVVGTLAWPSP--WVIVVGSFFSTCGAGLQSLTGAP 527
Cdd:COG0531  221 NIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   528 RLLQAIAKDNIIPflRVFGH-GKANGEPTWALLLTALIAELGILI--ASLDMVAPILSMFFLMCYLFVNLACAVQtLLRT 604
Cdd:COG0531  297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-RRRR 373
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....
gi 9507107   605 PNWRPRFKYYHWALSFLGMSLCLALMFVS---SWYYALVAMVIAGMIYKYIEYQ 655
Cdd:COG0531  374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
42-1085 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1354.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107      42 NHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRA-AKAPSMGT 120
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     121 LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGA 200
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     201 VGLCFYLGTTFAAAMYILGAIEILLTyiappaaIFYPSGtHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 280
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLRENG-SKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     281 LACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 360
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     361 nvtEIPGIPGAAAGvlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFPSVTGIMAGSNR 440
Cdd:TIGR00930  271 ---FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANI 302
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     441 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVS---------------------RNLVVGTL 499
Cdd:TIGR00930  303 SGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSL 382
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     500 AWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKA-NGEPTWALLLTALIAELGILIASLDMVA 578
Cdd:TIGR00930  383 VSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIA 462
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     579 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAE 658
Cdd:TIGR00930  463 PIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPD 542
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     659 KEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDedlhVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLES 738
Cdd:TIGR00930  543 VNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLEC 618
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     739 YGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEdPRAWKTFIDTVRCT 818
Cdd:TIGR00930  619 VKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDA 697
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     819 TAAHLALLVPKNIAFYPSNH--------------------------------------ERYLEGHIDVWWIVHDGGMLML 860
Cdd:TIGR00930  698 FDAHLAVVVVRNSEGLPISVlqvqeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLL 777
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     861 LPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMhnsDISAytYERTLMMEQRSQMLRQMR 940
Cdd:TIGR00930  778 LPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFR 852
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     941 LTKTERDREAqlvKDRHsalrleslysdeedesvtgadkiqMTWTRDKYMAEpwdpshapdnfRELvhikpdQSNVRRMH 1020
Cdd:TIGR00930  853 LHKTEKDREA---KDPK------------------------MTWTKPWKITD-----------AEL------QSNVRKSY 888
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 9507107    1021 TAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1085
Cdd:TIGR00930  889 RQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
123-695 5.11e-51

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 187.53  E-value: 5.11e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     123 GVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVpAGGSYFMISRSLGPEFGGAVG 202
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     203 L--CFYLGTTFAAAmyiLGAIEILLTYIAPPAAIFYPSGThdmssatlnnmrvyGTIFLTFMTLVVFVGVKYVNKFASLF 280
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDIPYLWVW--------------GAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     281 LACVIISILSIYVGGIKSAFDPpvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdpyflln 360
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIILLSGG---------------------------------------------------------- 164
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     361 nvteipgipGAAAGVLQENLWSAYLEKgevvekhglpstdtlglkeslslYVVADIATSFTVLVGIFFPSVTGIMAGSNR 440
Cdd:pfam00324  165 ---------NPNDGAIFRYLGDNGGKN-----------------------NFPPGFGKGFISVFVIAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     441 SGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVV------GTLAWPSpwVIVVGSFFS 514
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTA 290
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     515 TCGAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHGKANGEPTWALLLTALIAELGILIASLdmVAPILSMFFLMCYLFVNL 594
Cdd:pfam00324  291 ALSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGL 366
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     595 ACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR 674
Cdd:pfam00324  367 IVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVL 446
                          570       580
                   ....*....|....*....|.
gi 9507107     675 YALLRLEEGPPHTKNWRPQLL 695
Cdd:pfam00324  447 LFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
131-655 2.50e-34

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 137.34  E-value: 2.50e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   131 NIFGVILFLRLTWMVGTAGvLQALLIVLICCCCTLLTAISMSAIATNgvVP-AGGSYFMISRSLGPEFGGAVGLCFYLGT 209
Cdd:COG0531   25 AIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLLSY 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   210 TFAAAMYILGAIEILltyiappaAIFYPSGTHDmssatlnnmrVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISIL 289
Cdd:COG0531  102 VLAVAAVAVAFGGYL--------SSLFPAGGSV----------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   290 SIYVGGIksafdppvfpvcmlgnrtlsrdqfdicaktvvvdnetvatrlwtffchspnltadscdPYFLLNNVTEIPGIP 369
Cdd:COG0531  164 LFIVVGL----------------------------------------------------------FAFDPANFTPFLPAG 185
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   370 GAAAGVlqenlwsaylekgevvekhglpstdtlglkeslslyvvadiatsFTVLVGIFFpSVTGIMAGSNRSGDLRDAQK 449
Cdd:COG0531  186 GGLSGV--------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   450 SIPVGTILAIVTTSLVYFSSVILFGacieGVVLRDKYGDGVSRNLVVGTLAWPSP--WVIVVGSFFSTCGAGLQSLTGAP 527
Cdd:COG0531  221 NIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107   528 RLLQAIAKDNIIPflRVFGH-GKANGEPTWALLLTALIAELGILI--ASLDMVAPILSMFFLMCYLFVNLACAVQtLLRT 604
Cdd:COG0531  297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-RRRR 373
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....
gi 9507107   605 PNWRPRFKYYHWALSFLGMSLCLALMFVS---SWYYALVAMVIAGMIYKYIEYQ 655
Cdd:COG0531  374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
709-1085 5.46e-24

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 106.16  E-value: 5.46e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     709 PRLLTFASQLKAGKGLTIVGSVIQGSFleSYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRH 788
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGRL--SQKLRSELQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKP 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     789 NSVVLGWPYGWRQSE----------------------------------------------------------------- 803
Cdd:pfam03522   80 NILLMGYKSDWRTCDkeeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     804 DPRAWKTFIDTVRCTTAAHLALLV--------------------PKNIAFYPSNHERYLE-----------GHIDVWWIV 852
Cdd:pfam03522  160 NSKQDDDKSKLSKKDSNLSLSPDKstknpsgkdssksdklkkksPSIILRTASNEKEILNnitqfqkkqkkGTIDVWWLY 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     853 HDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLE-AEVEVVemhnSDISAYTYERTLMMEQ 931
Cdd:pfam03522  240 DDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDELEEEQRNMASLLSKFRIDySDLTVI----PDITKKPKKETKKFFD 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     932 rsQMLRQMRLTKTErdreaqlvKDRHSALRLeslySDEEDESVtgadkiqmtwtRDKymaepwdpshapdNFRELvhikp 1011
Cdd:pfam03522  316 --ELIEPFRLHEDD--------KEEESAEKI----TDSELEAL-----------KEK-------------TNRQL----- 352
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9507107    1012 dqsnvrrmhtavKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1085
Cdd:pfam03522  353 ------------RLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease_2 pfam13520
Amino acid permease;
411-652 9.03e-14

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 74.65  E-value: 9.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     411 YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRdaQKSIPVGTILAIVTTSLVYFSSVILFGACI--EGVVLRDKYGD 488
Cdd:pfam13520  181 TFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYILVNIAFFGVVpdDEIALSSGLGQ 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     489 GVS---RNLVVGTLAWpspwVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTALIA 565
Cdd:pfam13520  259 VAAllfQAVGGKWGAI----IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILS 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9507107     566 ELGILIASLDMVAPI----LSMFFLMCYLFVNLACAVqtLLRTPNWRPRFKYYHWALSFLGMsLCLALMFVSSWYYALVA 641
Cdd:pfam13520  335 LILLLLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGI-LFSLFLIVALFFPPVGP 411
                          250
                   ....*....|.
gi 9507107     642 MVIAGMIYKYI 652
Cdd:pfam13520  412 ATGSSLNYAII 422
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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