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Conserved domains on  [gi|33457348|ref|NP_061980|]
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myeloid-derived growth factor precursor [Homo sapiens]

Protein Classification

myeloid-derived growth factor( domain architecture ID 10566016)

myeloid-derived growth factor (MYDGF) is a bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UPF0556 pfam10572
UPF0556 domain; This putative domain has no known function. It is found in a variety of ...
 40-171 8.54e-72

UPF0556 domain; This putative domain has no known function. It is found in a variety of eukaryotic species often as a single domain protein but also found at the C-terminus of a few other protein contains other domains.


:

Pssm-ID: 463151  Cd Length: 125  Bit Score: 212.18  E-value: 8.54e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33457348    40 FDVRPGGVVHSFSHNvgpGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEY 119
Cdd:pfam10572   1 FDVKPGGVVHSVSEE---LDGFTCTFTYACQGGTNEEWQMTLGLSEDDGLYSCSVWRPQGKSYLFFTQFKLEVKGAKIEY 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 33457348   120 AMAYSkaafERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRT 171
Cdd:pfam10572  78 AEAYQ----GGDSDVPLKPEEYEVDKTEVSHVAGKFKSELSKLTVSARTGRD 125
 
Name Accession Description Interval E-value
UPF0556 pfam10572
UPF0556 domain; This putative domain has no known function. It is found in a variety of ...
 40-171 8.54e-72

UPF0556 domain; This putative domain has no known function. It is found in a variety of eukaryotic species often as a single domain protein but also found at the C-terminus of a few other protein contains other domains.


Pssm-ID: 463151  Cd Length: 125  Bit Score: 212.18  E-value: 8.54e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33457348    40 FDVRPGGVVHSFSHNvgpGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEY 119
Cdd:pfam10572   1 FDVKPGGVVHSVSEE---LDGFTCTFTYACQGGTNEEWQMTLGLSEDDGLYSCSVWRPQGKSYLFFTQFKLEVKGAKIEY 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 33457348   120 AMAYSkaafERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRT 171
Cdd:pfam10572  78 AEAYQ----GGDSDVPLKPEEYEVDKTEVSHVAGKFKSELSKLTVSARTGRD 125
 
Name Accession Description Interval E-value
UPF0556 pfam10572
UPF0556 domain; This putative domain has no known function. It is found in a variety of ...
 40-171 8.54e-72

UPF0556 domain; This putative domain has no known function. It is found in a variety of eukaryotic species often as a single domain protein but also found at the C-terminus of a few other protein contains other domains.


Pssm-ID: 463151  Cd Length: 125  Bit Score: 212.18  E-value: 8.54e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33457348    40 FDVRPGGVVHSFSHNvgpGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEY 119
Cdd:pfam10572   1 FDVKPGGVVHSVSEE---LDGFTCTFTYACQGGTNEEWQMTLGLSEDDGLYSCSVWRPQGKSYLFFTQFKLEVKGAKIEY 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 33457348   120 AMAYSkaafERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRT 171
Cdd:pfam10572  78 AEAYQ----GGDSDVPLKPEEYEVDKTEVSHVAGKFKSELSKLTVSARTGRD 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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