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Conserved domains on  [gi|29725607|ref|NP_061141|]
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protein unc-45 homolog A isoform 2 [Homo sapiens]

Protein Classification

UNC45-central domain-containing protein( domain architecture ID 10569479)

UNC45-central domain-containing protein similar to Homo sapiens SWI5-dependent HO expression protein 4 (SHE4) required for mother cell-specific ho expression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UNC45-central pfam11701
Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C. ...
 363-505 2.50e-31

Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C.elegans is expressed in two forms from different genomic positions in mammals, as a general tissue protein UNC-45a and a specific form Unc-45b expressed only in striated and skeletal muscle. All members carry up to three amino-terminal tetratricopeptide repeat (TPR) domains towards their N-terminal, a UCS domain at the C-terminal that contains a number of Arm repeats pfam00514 and this central region of approximately 400 residues. Both the general form and the muscle form of UNC-45 function in myotube formation through cell fusion. Myofibril formation requires both GC and SM UNC-45, consistent with the fact that the cytoskeleton is necessary for the development and maintenance of organized myofibrils. The S. pombe Rng3p, is crucial for cell shape, normal actin cytoskeleton, and contractile ring assembly, and is essential for assembly of the myosin II-containing progenitors of the contractile ring. Widespread defects in the cytoskeleton are found in null mutants of all three fungal proteins. Mammalian Unc45 is found to act as a specific chaperone during the folding of myosin and the assembly of striated muscle by forming a stable complex with the general chaperone Hsp90. The exact function of this central region is not known.


:

Pssm-ID: 432011  Cd Length: 151  Bit Score: 119.95  E-value: 2.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607   363 VTANSRMSASILLSKLfddlkCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESV 442
Cdd:pfam11701  14 LPESVRSLALLILSKL-----LEAAKEEFEEKFSEFITSLLADGTNDDLIIAFSALAALFPVPPDVASALFLSEGFLESL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29725607   443 IALCAS-EQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKcSEKDSIRIRALVGLCKL 505
Cdd:pfam11701  89 LPLVESkKSRKVELAALELLSAACIDKACREAISKNYVDWLEELLK-SSDDEIKALAAVVLAKL 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
28-125 1.12e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.96  E-value: 1.12e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDP---DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90
                ....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKN 125
Cdd:COG4785 157 YELAIADLEKALELDPND 174
 
Name Accession Description Interval E-value
UNC45-central pfam11701
Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C. ...
 363-505 2.50e-31

Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C.elegans is expressed in two forms from different genomic positions in mammals, as a general tissue protein UNC-45a and a specific form Unc-45b expressed only in striated and skeletal muscle. All members carry up to three amino-terminal tetratricopeptide repeat (TPR) domains towards their N-terminal, a UCS domain at the C-terminal that contains a number of Arm repeats pfam00514 and this central region of approximately 400 residues. Both the general form and the muscle form of UNC-45 function in myotube formation through cell fusion. Myofibril formation requires both GC and SM UNC-45, consistent with the fact that the cytoskeleton is necessary for the development and maintenance of organized myofibrils. The S. pombe Rng3p, is crucial for cell shape, normal actin cytoskeleton, and contractile ring assembly, and is essential for assembly of the myosin II-containing progenitors of the contractile ring. Widespread defects in the cytoskeleton are found in null mutants of all three fungal proteins. Mammalian Unc45 is found to act as a specific chaperone during the folding of myosin and the assembly of striated muscle by forming a stable complex with the general chaperone Hsp90. The exact function of this central region is not known.


Pssm-ID: 432011  Cd Length: 151  Bit Score: 119.95  E-value: 2.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607   363 VTANSRMSASILLSKLfddlkCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESV 442
Cdd:pfam11701  14 LPESVRSLALLILSKL-----LEAAKEEFEEKFSEFITSLLADGTNDDLIIAFSALAALFPVPPDVASALFLSEGFLESL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29725607   443 IALCAS-EQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKcSEKDSIRIRALVGLCKL 505
Cdd:pfam11701  89 LPLVESkKSRKVELAALELLSAACIDKACREAISKNYVDWLEELLK-SSDDEIKALAAVVLAKL 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
28-125 1.12e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.96  E-value: 1.12e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDP---DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90
                ....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKN 125
Cdd:COG4785 157 YELAIADLEKALELDPND 174
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 23-144 3.20e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 67.32  E-value: 3.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607    23 QLRKEGNELFKCGDYGGALAAYTQALGLDATPqdqaVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQAL 102
Cdd:TIGR00990 129 KLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP----VYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAY 204

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 29725607   103 EKLGRLDQAVLDLQ-RCVSLEPKNKVFQEAL-RNIGGQIQEKVR 144
Cdd:TIGR00990 205 DGLGKYADALLDLTaSCIIDGFRNEQSAQAVeRLLKKFAESKAK 248
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 24-166 5.07e-10

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 62.11  E-value: 5.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607   24 LRKEGNELFKCGDYGGALAAYTQALGLDATpqdQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALE 103
Cdd:PLN03088   5 LEDKAKEAFVDDDFALAVDLYTQAIDLDPN---NAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 29725607  104 KLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK----------VRYMSSTDAKVEQMFQILLDPEEK 166
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEekdlvqpvpsDLPSSVTAPPVEEADATPVVPPSK 154
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 26-91 1.23e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 1.23e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 29725607    26 KEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGD 91
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 92-125 6.36e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 6.36e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 29725607     92 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN 125
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
UNC45-central pfam11701
Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C. ...
 363-505 2.50e-31

Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C.elegans is expressed in two forms from different genomic positions in mammals, as a general tissue protein UNC-45a and a specific form Unc-45b expressed only in striated and skeletal muscle. All members carry up to three amino-terminal tetratricopeptide repeat (TPR) domains towards their N-terminal, a UCS domain at the C-terminal that contains a number of Arm repeats pfam00514 and this central region of approximately 400 residues. Both the general form and the muscle form of UNC-45 function in myotube formation through cell fusion. Myofibril formation requires both GC and SM UNC-45, consistent with the fact that the cytoskeleton is necessary for the development and maintenance of organized myofibrils. The S. pombe Rng3p, is crucial for cell shape, normal actin cytoskeleton, and contractile ring assembly, and is essential for assembly of the myosin II-containing progenitors of the contractile ring. Widespread defects in the cytoskeleton are found in null mutants of all three fungal proteins. Mammalian Unc45 is found to act as a specific chaperone during the folding of myosin and the assembly of striated muscle by forming a stable complex with the general chaperone Hsp90. The exact function of this central region is not known.


Pssm-ID: 432011  Cd Length: 151  Bit Score: 119.95  E-value: 2.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607   363 VTANSRMSASILLSKLfddlkCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESV 442
Cdd:pfam11701  14 LPESVRSLALLILSKL-----LEAAKEEFEEKFSEFITSLLADGTNDDLIIAFSALAALFPVPPDVASALFLSEGFLESL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29725607   443 IALCAS-EQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKcSEKDSIRIRALVGLCKL 505
Cdd:pfam11701  89 LPLVESkKSRKVELAALELLSAACIDKACREAISKNYVDWLEELLK-SSDDEIKALAAVVLAKL 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
28-125 1.12e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.96  E-value: 1.12e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDP---DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90
                ....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKN 125
Cdd:COG4785 157 YELAIADLEKALELDPND 174
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
28-136 1.49e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 77.35  E-value: 1.49e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG0457  15 GLAYRRLGRYEEAIEDYEKALELD---PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGR 91

                        90       100
                ....*....|....*....|....*....
gi 29725607 108 LDQAVLDLQRCVSLEPKNkvfQEALRNIG 136
Cdd:COG0457  92 YEEALEDYDKALELDPDD---AEALYNLG 117
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 14-141 6.14e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 79.27  E-value: 6.14e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  14 ATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVK 93
Cdd:COG3914  71 AAALLLLAALLELAALLLQALGRYEEALALYRRALALNP---DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE 147

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 29725607  94 ALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNIG------GQIQE 141
Cdd:COG3914 148 AYLNLGEALRRLGRLEEAIAALRRALELDPDN---AEALNNLGnalqdlGRLEE 198
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
28-216 1.31e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 1.31e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG0457  49 GLAYLRLGRYEEALADYEQALELDP---DDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGR 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607 108 LDQAVLDLQRCVSLEPKNkvfQEALRNIG------GQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVL 181
Cdd:COG0457 126 YDEAIEAYERALELDPDD---ADALYNLGialeklGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202

                       170       180       190
                ....*....|....*....|....*....|....*
gi 29725607 182 AREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAAL 216
Cdd:COG0457 203 LEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 28-193 8.64e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.33  E-value: 8.64e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG3914 119 GNLLLALGRLEEALAALRRALALNP---DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGR 195

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607 108 LDQAVLDLQRCVSLEPKN-KVFQEALRNiggqiqekvrYMSSTDAKVEQMFQILLdpeeKGTEKKQKASQNLVVLAREDA 186
Cdd:COG3914 196 LEEAIAAYRRALELDPDNaDAHSNLLFA----------LRQACDWEVYDRFEELL----AALARGPSELSPFALLYLPDD 261


                ....*..
gi 29725607 187 GAEKIFR 193
Cdd:COG3914 262 DPAELLA 268
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
28-192 3.15e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 3.15e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG0457  83 GLALQALGRYEEALEDYDKALELDP---DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGR 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607 108 LDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAG 187
Cdd:COG0457 160 YEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239


                ....*
gi 29725607 188 AEKIF 192
Cdd:COG0457 240 LYQYR 244
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
35-124 8.08e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.11  E-value: 8.08e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  35 GDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAEtEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLD 114
Cdd:COG3063   6 GDLEEAEEYYEKALELDP---DNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                        90
                ....*....|
gi 29725607 115 LQRCVSLEPK 124
Cdd:COG3063  82 LERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 31-123 2.38e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.06  E-value: 2.38e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  31 LFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQ 110
Cdd:COG5010  64 YNKLGDFEESLALLEQALQLDP---NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE 140

                        90
                ....*....|...
gi 29725607 111 AVLDLQRCVSLEP 123
Cdd:COG5010 141 AKAALQRALGTSP 153
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 23-144 3.20e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 67.32  E-value: 3.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607    23 QLRKEGNELFKCGDYGGALAAYTQALGLDATPqdqaVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQAL 102
Cdd:TIGR00990 129 KLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP----VYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAY 204

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 29725607   103 EKLGRLDQAVLDLQ-RCVSLEPKNKVFQEAL-RNIGGQIQEKVR 144
Cdd:TIGR00990 205 DGLGKYADALLDLTaSCIIDGFRNEQSAQAVeRLLKKFAESKAK 248
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 28-135 5.72e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.79  E-value: 5.72e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRLDP---DNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGD 100

                        90       100
                ....*....|....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKNKVFQEALRNI 135
Cdd:COG4235 101 YAEAIAAWQKLLALLPADAPARLLEASI 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 18-125 1.29e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.21  E-value: 1.29e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  18 ASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYR 97
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDP---DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLN 77

                        90       100
                ....*....|....*....|....*...
gi 29725607  98 RSQALEKLGRLDQAVLDLQRCVSLEPKN 125
Cdd:COG4783  78 LGLALLKAGDYDEALALLEKALKLDPEH 105
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 28-125 4.01e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 4.01e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG4783  45 GEILLQLGDLDEAIVLLHEALELD---PDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGR 121

                        90
                ....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKN 125
Cdd:COG4783 122 PDEAIAALEKALELDPDD 139
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 24-166 5.07e-10

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 62.11  E-value: 5.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607   24 LRKEGNELFKCGDYGGALAAYTQALGLDATpqdQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALE 103
Cdd:PLN03088   5 LEDKAKEAFVDDDFALAVDLYTQAIDLDPN---NAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 29725607  104 KLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK----------VRYMSSTDAKVEQMFQILLDPEEK 166
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEekdlvqpvpsDLPSSVTAPPVEEADATPVVPPSK 154
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
56-136 9.42e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 9.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  56 DQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNI 135
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD---AEALNNL 82


                .
gi 29725607 136 G 136
Cdd:COG0457  83 G 83
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
36-136 5.46e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.54  E-value: 5.46e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  36 DYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDL 115
Cdd:COG4785  51 AALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDF 130

                        90       100
                ....*....|....*....|.
gi 29725607 116 QRCVSLEPKNkvfQEALRNIG 136
Cdd:COG4785 131 DRALELDPDY---AYAYLNRG 148
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 28-125 6.11e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 6.11e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG2956 151 AELYLEQGDYDEAIEALEKALKLD---PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGD 227

                        90
                ....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKN 125
Cdd:COG2956 228 PEEALELLRKALELDPSD 245
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 35-135 7.00e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.74  E-value: 7.00e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  35 GDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLD 114
Cdd:COG2956 124 GDWEKAIEVLERLLKLG---PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAA 200

                        90       100
                ....*....|....*....|.
gi 29725607 115 LQRCVSLEPKNKVFQEALRNI 135
Cdd:COG2956 201 LERALEQDPDYLPALPRLAEL 221
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 30-131 8.13e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 51.53  E-value: 8.13e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  30 ELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVK---ALYRRSQALEKLG 106
Cdd:COG1729   2 ALLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELG 81

                        90       100
                ....*....|....*....|....*
gi 29725607 107 RLDQAVLDLQRCVSLEPKNKVFQEA 131
Cdd:COG1729  82 DYDKARATLEELIKKYPDSEAAKEA 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 28-129 1.37e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 1.37e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG2956  49 GNLYRRRGEYDRAIRIHQKLLERD---PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                        90       100
                ....*....|....*....|..
gi 29725607 108 LDQAVLDLQRCVSLEPKNKVFQ 129
Cdd:COG2956 126 WEKAIEVLERLLKLGPENAHAY 147
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 57-136 1.56e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.35  E-value: 1.56e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  57 QAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNIG 136
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE---PEARLNLG 79
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 40-136 7.42e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.23  E-value: 7.42e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  40 ALAAYTQALGLDatPQDqAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCV 119
Cdd:COG4235   2 AIARLRQALAAN--PND-AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78

                        90
                ....*....|....*..
gi 29725607 120 SLEPKNkvfQEALRNIG 136
Cdd:COG4235  79 ALDPDN---PEALYLLG 92
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 27-135 1.14e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 1.14e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  27 EGNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLG 106
Cdd:COG2956  14 KGLNYLLNGQPDKAIDLLEEALELD---PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                        90       100
                ....*....|....*....|....*....
gi 29725607 107 RLDQAVLDLQRCVSLEPKNKVFQEALRNI 135
Cdd:COG2956  91 LLDRAEELLEKLLELDPDDAEALRLLAEI 119
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 28-125 3.05e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.73  E-value: 3.05e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDatPQDQAVLhRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG2956  83 AQDYLKAGLLDRAEELLEKLLELD--PDDAEAL-RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                        90
                ....*....|....*...
gi 29725607 108 LDQAVLDLQRCVSLEPKN 125
Cdd:COG2956 160 YDEAIEALEKALKLDPDC 177
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
67-136 3.33e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.32  E-value: 3.33e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  67 CHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAvLDLQRCVSLEPKNkvfQEALRNIG 136
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNN---AEALLNLA 66
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
28-117 4.74e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.76  E-value: 4.74e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGLDatPQDQAVlHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 107
Cdd:COG4785 114 GLAYLLLGDYDAALEDFDRALELD--PDYAYA-YLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDP 190

                        90
                ....*....|
gi 29725607 108 lDQAVLDLQR 117
Cdd:COG4785 191 -EKALALLLE 199
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 40-136 5.25e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 5.25e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  40 ALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCV 119
Cdd:COG5010  36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115

                        90
                ....*....|....*..
gi 29725607 120 SLEPKNkvfQEALRNIG 136
Cdd:COG5010 116 ALSPDN---PNAYSNLA 129
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 32-125 1.41e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.83  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607    32 FKC--GDYGGALAAYTQALGLDATPQDQAVlhrNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLD 109
Cdd:TIGR00990 340 FKClkGKHLEALADLSKSIELDPRVTQSYI---KRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFA 416

                          90
                  ....*....|....*.
gi 29725607   110 QAVLDLQRCVSLEPKN 125
Cdd:TIGR00990 417 QAGKDYQKSIDLDPDF 432
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 40-145 9.70e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.14  E-value: 9.70e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  40 ALAAYTQALGLDATPQDQAVLHRNRAACHlKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCV 119
Cdd:COG3914  61 ALAAGEAAAAAAALLLLAALLELAALLLQ-ALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRAL 139

                        90       100
                ....*....|....*....|....*.
gi 29725607 120 SLEPKnkvFQEALRNIGGQIQEKVRY 145
Cdd:COG3914 140 ALNPD---FAEAYLNLGEALRRLGRL 162
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 26-91 1.23e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 1.23e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 29725607    26 KEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGD 91
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
28-111 1.34e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 44.49  E-value: 1.34e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  28 GNELFKCGDYGGALAAYTQALGlDATPQDQAVLHRnRAACHLKLEDYDKAETEASKAIEKD----GGDVKALYRRsqALE 103
Cdd:COG4700  96 ADALLELGRYDEAIELYEEALT-GIFADDPHILLG-LAQALFELGRYAEALETLEKLIAKNpdfkSSDAHLLYAR--ALE 171


                ....*...
gi 29725607 104 KLGRLDQA 111
Cdd:COG4700 172 ALGDLEAA 179
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 68-142 4.43e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 4.43e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 29725607  68 HLKLEDYDKAETEASKAIEKDGGDV---KALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIgGQIQEK 142
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKL-GLSYLE 79
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 76-165 7.45e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.37  E-value: 7.45e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  76 KAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNIGGqiqekVRYMSSTDAKVEQ 155
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAE-----ALLAAGDTEEAEE 72

                        90
                ....*....|..
gi 29725607 156 MFQ--ILLDPEE 165
Cdd:COG4235  73 LLEraLALDPDN 84
TPR_1 pfam00515
Tetratricopeptide repeat;
92-125 1.09e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 1.09e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 29725607    92 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN 125
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_11 pfam13414
TPR repeat;
28-71 1.80e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.07  E-value: 1.80e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 29725607    28 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKL 71
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLD---PDNPEAYYNLGLAYYKL 41
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 35-111 4.64e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 38.88  E-value: 4.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607   35 GDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKAL--------YRRSQALEKlG 106
Cdd:PRK02603  49 GEYAEALENYEEALKLEEDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALnniaviyhKRGEKAEEA-G 127


                 ....*
gi 29725607  107 RLDQA 111
Cdd:PRK02603 128 DQDEA 132
TPR_8 pfam13181
Tetratricopeptide repeat;
92-124 5.68e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.07  E-value: 5.68e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 29725607    92 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK 124
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 92-125 6.36e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 6.36e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 29725607     92 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN 125
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
40-136 6.48e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.13  E-value: 6.48e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29725607  40 ALAAYTQALGLDATPQDQAVLHRNRA-ACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRC 118
Cdd:COG4785  20 SKAAILLAALLFAAVLALAIALADLAlALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQA 99

                        90
                ....*....|....*...
gi 29725607 119 VSLEPKNKvfqEALRNIG 136
Cdd:COG4785 100 LELDPDLA---EAYNNRG 114
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 92-124 9.03e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.81  E-value: 9.03e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 29725607    92 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK 124
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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