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Conserved domains on  [gi|61563742|ref|NP_060382|]
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probable E3 ubiquitin-protein ligase HERC6 isoform 1 [Homo sapiens]

Protein Classification

E3 ubiquitin-protein ligase HERC family protein( domain architecture ID 18804227)

E3 ubiquitin-protein ligase HERC (HECT and RCC1 domain) family protein similar to human E3 ISG15--protein ligase HERC5, the major E3 ligase for ISG15 conjugation, that functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 672-1014 8.78e-135

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


:

Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 410.03  E-value: 8.78e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  672 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG-SCMWFPAK 750
Cdd:cd00078    1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  751 PKP---EKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirF 827
Cdd:cd00078   81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGDEDDLELT--F 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  828 SIH-----WDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG 902
Cdd:cd00078  159 TIEldssfGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  903 NTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET-FSERDHPT 981
Cdd:cd00078  239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVgSPDDRLPT 318

                        330       340       350
                 ....*....|....*....|....*....|...
gi 61563742  982 SITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:cd00078  319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 3.85e-68

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 231.79  E-value: 3.85e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742   27 QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETlIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:COG5184    2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN-VVA-VAAGGDHTCALKADGTVWCWGNNSYGQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  107 LGIGEfKEISFTPKKIMTLNDIKiiQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGkEFPSQASPQRVR-SLEGIplAQ 185
Cdd:COG5184   80 LGDGT-TTDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDG-TTTNRLTPVQVDaGLSGV--VA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  186 VAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALKnlGVVYISCGDAHTAVLTQDGKVFTFGDNRS 265
Cdd:COG5184  154 IAAGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSS 228

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 61563742  266 GQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFG 313
Cdd:COG5184  229 GQLGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWG 274
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 672-1014 8.78e-135

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 410.03  E-value: 8.78e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  672 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG-SCMWFPAK 750
Cdd:cd00078    1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  751 PKP---EKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirF 827
Cdd:cd00078   81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGDEDDLELT--F 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  828 SIH-----WDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG 902
Cdd:cd00078  159 TIEldssfGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  903 NTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET-FSERDHPT 981
Cdd:cd00078  239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVgSPDDRLPT 318

                        330       340       350
                 ....*....|....*....|....*....|...
gi 61563742  982 SITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:cd00078  319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 726-1014 9.66e-78

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 256.77  E-value: 9.66e-78
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    726 EEMTKPEYGMFMYPEMGSC-MWF----PAKPKPEKKRYF-LFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKE 799
Cdd:pfam00632    5 KELFDPNYGLFEYETEDDRtYWFnpssSESPDLELLDYFkFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLEDLES 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    800 LSPRLGKSLQEvLDDAADDIGDALCIRFSI--HWDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQR 877
Cdd:pfam00632   85 IDPELYKSLKS-LLNMDNDDDEDLGLTFTIpvFGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQLEAFRK 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    878 GFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLH 957
Cdd:pfam00632  164 GFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVTGSSRLP 243

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 61563742    958 ARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:pfam00632  244 VGGFKSLPKFTIVRKGGDDDDRlPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGF 301
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 699-1014 2.97e-74

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 248.30  E-value: 2.97e-74
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     699 KVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYF-LFGMLCGLSLFNLNV 774
Cdd:smart00119    5 RVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSgfaNEEHLSYFrFIGRVLGKALYDNRL 84

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     775 ANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirFSIHwDQND------VDLIPNGISIPVD 848
Cdd:smart00119   85 LDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLLLNNDTSEELDLT--FSIV-LTSEfgqvkvVELKPGGSNIPVT 161

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     849 QTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTI 928
Cdd:smart00119  162 EENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQTI 241

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     929 QLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVA 1007
Cdd:smart00119  242 KWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALSPKFTIRKAGSDDERlPTAHTCFNRLKLPPYSSKEILREKLLLA 321


                    ....*..
gi 61563742    1008 INNNRGF 1014
Cdd:smart00119  322 INEGKGF 328
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 3.85e-68

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 231.79  E-value: 3.85e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742   27 QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETlIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:COG5184    2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN-VVA-VAAGGDHTCALKADGTVWCWGNNSYGQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  107 LGIGEfKEISFTPKKIMTLNDIKiiQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGkEFPSQASPQRVR-SLEGIplAQ 185
Cdd:COG5184   80 LGDGT-TTDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDG-TTTNRLTPVQVDaGLSGV--VA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  186 VAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALKnlGVVYISCGDAHTAVLTQDGKVFTFGDNRS 265
Cdd:COG5184  154 IAAGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSS 228

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 61563742  266 GQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFG 313
Cdd:COG5184  229 GQLGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWG 274
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
578-1014 1.71e-64

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 235.05  E-value: 1.71e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  578 RLPENTFNINELSNLLNFYID-RGRQLFRDNHLIPAETPSPVIFsDFPFIFNSLSKIKLLQA---DSHIKMQMSEKK--- 650
Cdd:COG5021  400 GQFLFSDFLTSSSTYEDLRREqLGRESDESFYVASNVQQQRASR-EGPLLSGWKTRLNNLYRfyfVEHRKKTLTKNDsrl 478

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  651 --AYMLMHETILQKKDEF-------------PPSPRFILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGG 715
Cdd:COG5021  479 gsFISLNKLDIRRIKEDKrrklfyslkqkakIFDPYLHIKVRRDRVFEDSYREIMDESGDDLKKTLEIEFVGEEGIDAGG 558

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  716 VSSEFFHCMFEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYFLF-GMLCGLSLFNLNVANLPFPLALYKKLLDQK 791
Cdd:COG5021  559 LTREWLFLLSKEMFNPDYGLFEYITEDLYTLPINPLssiNPEHLSYFKFlGRVIGKAIYDSRILDVQFSKAFYKKLLGKP 638

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  792 PSLEDLKELSPRLGKSLQEVLDDAADDIGdaLCIRFSI-HWDQND---VDLIPNGISIPVDQTNKRDYVSKYIDYIFNVS 867
Cdd:COG5021  639 VSLVDLESLDPELYRSLVWLLNNDIDETI--LDLTFTVeDDSFGEsrtVELIPNGRNISVTNENKKEYVKKVVDYKLNKR 716

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  868 VKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG-NTDYDWKQFEQNSKYeQGYQKSHPTIQLFWKAFHKLTLDEKKKF 946
Cdd:COG5021  717 VEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAY-HGYTEDSPIIVWFWEIISEFDFEERAKL 795

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 61563742  947 LFFLTGRDRLHARGIQ----KMEIVFRCPETFSERDH--PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:COG5021  796 LQFVTGTSRIPINGFKdlqgSDGVRKFTIEKGGTDDDrlPSAHTCFNRLKLPEYSSKEKLRSKLLTAINEGAGF 869
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
93-143 1.46e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 74.48  E-value: 1.46e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 61563742     93 KGRVFAWGAGSEGQLGIGEFKEiSFTPKKIMTLNDIKIIQVSCGHYHSLAL 143
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTEN-VLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 672-1014 8.78e-135

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 410.03  E-value: 8.78e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  672 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG-SCMWFPAK 750
Cdd:cd00078    1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  751 PKP---EKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirF 827
Cdd:cd00078   81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGDEDDLELT--F 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  828 SIH-----WDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG 902
Cdd:cd00078  159 TIEldssfGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  903 NTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET-FSERDHPT 981
Cdd:cd00078  239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVgSPDDRLPT 318

                        330       340       350
                 ....*....|....*....|....*....|...
gi 61563742  982 SITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:cd00078  319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 726-1014 9.66e-78

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 256.77  E-value: 9.66e-78
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    726 EEMTKPEYGMFMYPEMGSC-MWF----PAKPKPEKKRYF-LFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKE 799
Cdd:pfam00632    5 KELFDPNYGLFEYETEDDRtYWFnpssSESPDLELLDYFkFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLEDLES 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    800 LSPRLGKSLQEvLDDAADDIGDALCIRFSI--HWDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQR 877
Cdd:pfam00632   85 IDPELYKSLKS-LLNMDNDDDEDLGLTFTIpvFGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQLEAFRK 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    878 GFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLH 957
Cdd:pfam00632  164 GFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVTGSSRLP 243

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 61563742    958 ARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:pfam00632  244 VGGFKSLPKFTIVRKGGDDDDRlPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGF 301
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 699-1014 2.97e-74

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 248.30  E-value: 2.97e-74
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     699 KVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYF-LFGMLCGLSLFNLNV 774
Cdd:smart00119    5 RVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSgfaNEEHLSYFrFIGRVLGKALYDNRL 84

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     775 ANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirFSIHwDQND------VDLIPNGISIPVD 848
Cdd:smart00119   85 LDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLLLNNDTSEELDLT--FSIV-LTSEfgqvkvVELKPGGSNIPVT 161

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     849 QTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTI 928
Cdd:smart00119  162 EENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQTI 241

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742     929 QLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVA 1007
Cdd:smart00119  242 KWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALSPKFTIRKAGSDDERlPTAHTCFNRLKLPPYSSKEILREKLLLA 321


                    ....*..
gi 61563742    1008 INNNRGF 1014
Cdd:smart00119  322 INEGKGF 328
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 3.85e-68

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 231.79  E-value: 3.85e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742   27 QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETlIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:COG5184    2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN-VVA-VAAGGDHTCALKADGTVWCWGNNSYGQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  107 LGIGEfKEISFTPKKIMTLNDIKiiQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGkEFPSQASPQRVR-SLEGIplAQ 185
Cdd:COG5184   80 LGDGT-TTDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDG-TTTNRLTPVQVDaGLSGV--VA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  186 VAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALKnlGVVYISCGDAHTAVLTQDGKVFTFGDNRS 265
Cdd:COG5184  154 IAAGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSS 228

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 61563742  266 GQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFG 313
Cdd:COG5184  229 GQLGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWG 274
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-315 1.08e-66

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 227.94  E-value: 1.08e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    3 FCWGADSR-ELQRRRTAGSPGAELL-------QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALET 74
Cdd:COG5184   20 WCWGDNSYgQLGDGTTTDRSTPVRVpglsnvvAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRTTPVKVPGLTG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742   75 liVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEiSFTPKKImTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Cdd:COG5184  100 --VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTN-RLTPVQV-DAGLSGVVAIAAGGYHTCALKSDGTVWCWGA 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  155 NSHGQLGLGkEFPSQASPQRVRSLEGIplAQVAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALK 234
Cdd:COG5184  176 NSYGQLGDG-TTTDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQL---GDGTTTDRATPVQVAGLT 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  235 NlgVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFGH 314
Cdd:COG5184  250 G--VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG-VVAVAAGSSHTCA-LLTDGTVWCWGD 325


                 .
gi 61563742  315 G 315
Cdd:COG5184  326 N 326
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
578-1014 1.71e-64

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 235.05  E-value: 1.71e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  578 RLPENTFNINELSNLLNFYID-RGRQLFRDNHLIPAETPSPVIFsDFPFIFNSLSKIKLLQA---DSHIKMQMSEKK--- 650
Cdd:COG5021  400 GQFLFSDFLTSSSTYEDLRREqLGRESDESFYVASNVQQQRASR-EGPLLSGWKTRLNNLYRfyfVEHRKKTLTKNDsrl 478

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  651 --AYMLMHETILQKKDEF-------------PPSPRFILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGG 715
Cdd:COG5021  479 gsFISLNKLDIRRIKEDKrrklfyslkqkakIFDPYLHIKVRRDRVFEDSYREIMDESGDDLKKTLEIEFVGEEGIDAGG 558

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  716 VSSEFFHCMFEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYFLF-GMLCGLSLFNLNVANLPFPLALYKKLLDQK 791
Cdd:COG5021  559 LTREWLFLLSKEMFNPDYGLFEYITEDLYTLPINPLssiNPEHLSYFKFlGRVIGKAIYDSRILDVQFSKAFYKKLLGKP 638

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  792 PSLEDLKELSPRLGKSLQEVLDDAADDIGdaLCIRFSI-HWDQND---VDLIPNGISIPVDQTNKRDYVSKYIDYIFNVS 867
Cdd:COG5021  639 VSLVDLESLDPELYRSLVWLLNNDIDETI--LDLTFTVeDDSFGEsrtVELIPNGRNISVTNENKKEYVKKVVDYKLNKR 716

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  868 VKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG-NTDYDWKQFEQNSKYeQGYQKSHPTIQLFWKAFHKLTLDEKKKF 946
Cdd:COG5021  717 VEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAY-HGYTEDSPIIVWFWEIISEFDFEERAKL 795

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 61563742  947 LFFLTGRDRLHARGIQ----KMEIVFRCPETFSERDH--PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
Cdd:COG5021  796 LQFVTGTSRIPINGFKdlqgSDGVRKFTIEKGGTDDDrlPSAHTCFNRLKLPEYSSKEKLRSKLLTAINEGAGF 869
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-280 3.46e-59

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 206.75  E-value: 3.46e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742    3 FCWGADSR------ELQRRRT----AGSPGAEllQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQAL 72
Cdd:COG5184   70 WCWGNNSYgqlgdgTTTDRTTpvkvPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAG 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742   73 ETLIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISfTPKKIMTLNDIkiIQVSCGHYHSLALSKDSQVFSW 152
Cdd:COG5184  148 LSGVVA-IAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRP-TPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCW 223

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  153 GKNSHGQLGLGkEFPSQASPQRVRSLEGIplAQVAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGA 232
Cdd:COG5184  224 GSNSSGQLGDG-TTTDRATPVQVAGLTGV--VAIAAGGSHTCALKSDGTVWCWGDNSYGQL---GDGTTTDRSTPVKVPG 297

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 61563742  233 LKNlgVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQ 280
Cdd:COG5184  298 LSG--VVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 131-317 5.51e-42

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 157.45  E-value: 5.51e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  131 IQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSqASPQRVRSLEGIplAQVAAGGAHSFALSLCGTSFGWGSNSA 210
Cdd:COG5184    1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDR-STPVRVPGLSNV--VAVAAGGDHTCALKADGTVWCWGNNSY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61563742  211 GQLalsGRNVPVQSNKPLSVGALKNlgVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVS 290
Cdd:COG5184   78 GQL---GDGTTTDRTTPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGLSGVV 152

                        170       180
                 ....*....|....*....|....*..
gi 61563742  291 QIDCGSYHTLAyVHTTGQVVSFGHGPS 317
Cdd:COG5184  153 AIAAGGYHTCA-LKSDGTVWCWGANSY 178
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
93-143 1.46e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 74.48  E-value: 1.46e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 61563742     93 KGRVFAWGAGSEGQLGIGEFKEiSFTPKKIMTLNDIKIIQVSCGHYHSLAL 143
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTEN-VLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
146-196 3.25e-14

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 67.54  E-value: 3.25e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 61563742    146 DSQVFSWGKNSHGQLGLGKEFpSQASPQRVRSLEGIPLAQVAAGGAHSFAL 196
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTE-NVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
254-301 2.99e-10

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 56.37  E-value: 2.99e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 61563742    254 DGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGSYHTLA 301
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNkVVQVACGGDHTVA 49
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
130-159 1.38e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 53.97  E-value: 1.38e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 61563742    130 IIQVSCGHYHSLALSKDSQVFSWGKNSHGQ 159
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
238-267 7.58e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 52.04  E-value: 7.58e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 61563742    238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQ 267
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
203-251 5.14e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 50.21  E-value: 5.14e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 61563742    203 FGWGSNSAGQLalsGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251
Cdd:pfam00415    5 YTWGRNDYGQL---GLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
41-90 6.51e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 47.13  E-value: 6.51e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 61563742     41 NHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAV 90
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
27-54 2.54e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.03  E-value: 2.54e-05
                           10        20
                   ....*....|....*....|....*...
gi 61563742     27 QAASGERHSLLLLTNHRVLSCGDNSRGQ 54
Cdd:pfam13540    3 SVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
77-106 1.02e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 40.10  E-value: 1.02e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 61563742     77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
184-212 1.52e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 39.71  E-value: 1.52e-04
                           10        20
                   ....*....|....*....|....*....
gi 61563742    184 AQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Cdd:pfam13540    2 VSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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