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Conserved domains on  [gi|117414143|ref|NP_060103|]
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terminal nucleotidyltransferase 5A [Homo sapiens]

Protein Classification

terminal nucleotidyltransferase( domain architecture ID 10546801)

terminal nucleotidyltransferase may act as a non-canonical poly(A) RNA polymerase

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NTP_transf_7 pfam07984
Nucleotidyltransferase; This family contains many hypothetical proteins. It also includes four ...
66-383 0e+00

Nucleotidyltransferase; This family contains many hypothetical proteins. It also includes four nematode prion-like proteins. This domain has been identified as part of the nucleotidyltransferase superfamily.


:

Pssm-ID: 462329  Cd Length: 320  Bit Score: 649.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143   66 LNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFC 145
Cdd:pfam07984   1 LTYEQVRRLDQVLNEVVPIHGRGNFPTLEVKLKDLIQVVRDRLEEKGIHVRDVRLNGSAASYVLAGDNGLSYNDLDLIFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  146 ADLRGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQ 225
Cdd:pfam07984  81 VDLSSERDFQVIKEAVLDCLLDFLPEGVNKEKITSCTLKEAYVQKMVKVSNDGDRWSLISLSNNNGKNVELKFVDSMRRQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  226 FEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR 305
Cdd:pfam07984 161 FEFSVDSFQIILDSLLSFYDCSSVPMSENFYPTVVAESVYGDFEEALDHLHNRLIATRNPEEIRGGGLLKYCNLLVRGYK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  306 PAS-DEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDR-KYEYLMTLHGVVNESTVCLMGHERRQTLNLITM 383
Cdd:pfam07984 241 PADpEEIKALERYMCSRFFIDFPDVEEQQRKLESYLDNHFVGEEEQlKYDYLMTLRRVVDESTVCLMGHERRQTLNLIDK 320
 
Name Accession Description Interval E-value
NTP_transf_7 pfam07984
Nucleotidyltransferase; This family contains many hypothetical proteins. It also includes four ...
66-383 0e+00

Nucleotidyltransferase; This family contains many hypothetical proteins. It also includes four nematode prion-like proteins. This domain has been identified as part of the nucleotidyltransferase superfamily.


Pssm-ID: 462329  Cd Length: 320  Bit Score: 649.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143   66 LNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFC 145
Cdd:pfam07984   1 LTYEQVRRLDQVLNEVVPIHGRGNFPTLEVKLKDLIQVVRDRLEEKGIHVRDVRLNGSAASYVLAGDNGLSYNDLDLIFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  146 ADLRGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQ 225
Cdd:pfam07984  81 VDLSSERDFQVIKEAVLDCLLDFLPEGVNKEKITSCTLKEAYVQKMVKVSNDGDRWSLISLSNNNGKNVELKFVDSMRRQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  226 FEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR 305
Cdd:pfam07984 161 FEFSVDSFQIILDSLLSFYDCSSVPMSENFYPTVVAESVYGDFEEALDHLHNRLIATRNPEEIRGGGLLKYCNLLVRGYK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  306 PAS-DEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDR-KYEYLMTLHGVVNESTVCLMGHERRQTLNLITM 383
Cdd:pfam07984 241 PADpEEIKALERYMCSRFFIDFPDVEEQQRKLESYLDNHFVGEEEQlKYDYLMTLRRVVDESTVCLMGHERRQTLNLIDK 320
 
Name Accession Description Interval E-value
NTP_transf_7 pfam07984
Nucleotidyltransferase; This family contains many hypothetical proteins. It also includes four ...
66-383 0e+00

Nucleotidyltransferase; This family contains many hypothetical proteins. It also includes four nematode prion-like proteins. This domain has been identified as part of the nucleotidyltransferase superfamily.


Pssm-ID: 462329  Cd Length: 320  Bit Score: 649.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143   66 LNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFC 145
Cdd:pfam07984   1 LTYEQVRRLDQVLNEVVPIHGRGNFPTLEVKLKDLIQVVRDRLEEKGIHVRDVRLNGSAASYVLAGDNGLSYNDLDLIFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  146 ADLRGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQ 225
Cdd:pfam07984  81 VDLSSERDFQVIKEAVLDCLLDFLPEGVNKEKITSCTLKEAYVQKMVKVSNDGDRWSLISLSNNNGKNVELKFVDSMRRQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  226 FEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR 305
Cdd:pfam07984 161 FEFSVDSFQIILDSLLSFYDCSSVPMSENFYPTVVAESVYGDFEEALDHLHNRLIATRNPEEIRGGGLLKYCNLLVRGYK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117414143  306 PAS-DEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDR-KYEYLMTLHGVVNESTVCLMGHERRQTLNLITM 383
Cdd:pfam07984 241 PADpEEIKALERYMCSRFFIDFPDVEEQQRKLESYLDNHFVGEEEQlKYDYLMTLRRVVDESTVCLMGHERRQTLNLIDK 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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