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Conserved domains on  [gi|89276787|ref|NP_059516|]
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beta-adducin isoform b [Homo sapiens]

Protein Classification

class II aldolase/adducin head domain-containing protein; class II aldolase/adducin family protein( domain architecture ID 10087020)

class II aldolase/adducin head domain-containing protein involved in catalyzing central steps of carbohydrate metabolism; it promotes carbon-carbon bond cleavage and stabilizes enolate intermediates using divalent cations; class II aldolase/adducin family protein similar to 3-oxo-tetronate 4-phosphate decarboxylase, which catalyzes decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 130-340 2.68e-73

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


:

Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 232.64  E-value: 2.68e-73
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 130 ERLMRcKISSVYRLLDLYGWaqlsDTYVTLRVSKEQD---HFLISPKGVSCSEVTASSLIKVNILGEVVE--KGSSCFPv 204
Cdd:cd00398   1 EKLKR-KIIAACLLLDLYGW----VTGTGGNVSARDRdrgYFLITPSGVDYEEMTASDLVVVDAQGKVVEgkKPSSETP- 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 205 dttgfcLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV---GDMAYYDFNGEMeQEADRINLQKCLG-P 280
Cdd:cd00398  75 ------LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfP 147

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 89276787 281 TCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSAGGV--ENLILLEQEKHRPH 340
Cdd:cd00398 148 NSKAVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLppISLELLNKEYLRKH 209
 
Name Accession Description Interval E-value
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 130-340 2.68e-73

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 232.64  E-value: 2.68e-73
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 130 ERLMRcKISSVYRLLDLYGWaqlsDTYVTLRVSKEQD---HFLISPKGVSCSEVTASSLIKVNILGEVVE--KGSSCFPv 204
Cdd:cd00398   1 EKLKR-KIIAACLLLDLYGW----VTGTGGNVSARDRdrgYFLITPSGVDYEEMTASDLVVVDAQGKVVEgkKPSSETP- 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 205 dttgfcLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV---GDMAYYDFNGEMeQEADRINLQKCLG-P 280
Cdd:cd00398  75 ------LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfP 147

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 89276787 281 TCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSAGGV--ENLILLEQEKHRPH 340
Cdd:cd00398 148 NSKAVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLppISLELLNKEYLRKH 209
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 130-379 6.89e-73

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 232.82  E-value: 6.89e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  130 ERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVekGSSCFPVDTTGF 209
Cdd:PRK07044  14 EWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVV--DDSPYPVNPAGF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  210 CLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV-GDMAYYDFNGEMEQEADRINLQKCLGPtCKILVLR 288
Cdd:PRK07044  92 TIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGD-KPAMLLR 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  289 NHGVVALGDTVEEAFYKIFHLQAACEIQVSALSsaGGVENLILleqekhrPHEVGSVQWAGSTFGPMQKSrlGEHEFEAL 368
Cdd:PRK07044 171 NHGLLTVGRTVAEAFLLMYTLERACEIQVAAQA--GGGELVLP-------PPEVAERTARQSLFDPGAGA--GELAWPAL 239

                        250
                 ....*....|...
gi 89276787  369 MRMLD--NLGYRT 379
Cdd:PRK07044 240 LRKLDriDPGYRD 252
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 135-317 2.83e-52

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 176.20  E-value: 2.83e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787   135 CKISSVYRLLDLYGWAQLSDTYVTLRVskEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKG---SSCFPvdttgfcL 211
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRL--PGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGGlkpSSETP-------L 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787   212 HSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNA--LLVGDMAYYDfNGEMEQEADRINLQKCLGPTCKILVLRN 289
Cdd:pfam00596  72 HLAIYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAadFLGGDIPIIP-YYTPGTEELGERIAEALGGDRKAVLLRN 150

                         170       180
                  ....*....|....*....|....*...
gi 89276787   290 HGVVALGDTVEEAFYKIFHLQAACEIQV 317
Cdd:pfam00596 151 HGLLVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 137-317 4.20e-48

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 165.50  E-value: 4.20e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787    137 ISSVYRLLDLYGWAQLSDTYVTLRVsKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSscFPVDTTGFCLHSAIY 216
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARV-GEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGG--GPKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787    217 AARPDVRCIIHLHTPATAAVSAMKW--GLLPVSHNALLVG-DMAYYDFNGEMEQEADRI-NLQKCLGPT---CKILVLRN 289
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALGKplPLLPTEQAAAFLGgEIPYAPYAGPGTELAEEGaELAEALAEAlpdRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 89276787    290 HGVVALGDTVEEAFYKIFHLQAACEIQV 317
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 130-338 3.05e-47

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 163.85  E-value: 3.05e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 130 ERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVskEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSscfpVDTTGF 209
Cdd:COG0235   3 EEELREELAAAGRRLARRGLVDGTAGNISVRL--DDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDL----KPSSET 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 210 CLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHN--ALLVGDMAYYDFNG-EMEQEADRInlQKCLGpTCKILV 286
Cdd:COG0235  77 PLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEQTeaAAFLGDVPVVPYAGpGTEELAEAI--AEALG-DRPAVL 153

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 89276787 287 LRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALsSAGGVENLILLEQEKHR 338
Cdd:COG0235 154 LRNHGVVVWGKDLAEAFDRAEVLEEAARIQLLAL-ALGGPLVLSDEEIDKLA 204
 
Name Accession Description Interval E-value
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 130-340 2.68e-73

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 232.64  E-value: 2.68e-73
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 130 ERLMRcKISSVYRLLDLYGWaqlsDTYVTLRVSKEQD---HFLISPKGVSCSEVTASSLIKVNILGEVVE--KGSSCFPv 204
Cdd:cd00398   1 EKLKR-KIIAACLLLDLYGW----VTGTGGNVSARDRdrgYFLITPSGVDYEEMTASDLVVVDAQGKVVEgkKPSSETP- 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 205 dttgfcLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV---GDMAYYDFNGEMeQEADRINLQKCLG-P 280
Cdd:cd00398  75 ------LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfP 147

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 89276787 281 TCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSAGGV--ENLILLEQEKHRPH 340
Cdd:cd00398 148 NSKAVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLppISLELLNKEYLRKH 209
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 130-379 6.89e-73

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 232.82  E-value: 6.89e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  130 ERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVekGSSCFPVDTTGF 209
Cdd:PRK07044  14 EWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVV--DDSPYPVNPAGF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  210 CLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV-GDMAYYDFNGEMEQEADRINLQKCLGPtCKILVLR 288
Cdd:PRK07044  92 TIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGD-KPAMLLR 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  289 NHGVVALGDTVEEAFYKIFHLQAACEIQVSALSsaGGVENLILleqekhrPHEVGSVQWAGSTFGPMQKSrlGEHEFEAL 368
Cdd:PRK07044 171 NHGLLTVGRTVAEAFLLMYTLERACEIQVAAQA--GGGELVLP-------PPEVAERTARQSLFDPGAGA--GELAWPAL 239

                        250
                 ....*....|...
gi 89276787  369 MRMLD--NLGYRT 379
Cdd:PRK07044 240 LRKLDriDPGYRD 252
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 135-317 2.83e-52

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 176.20  E-value: 2.83e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787   135 CKISSVYRLLDLYGWAQLSDTYVTLRVskEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKG---SSCFPvdttgfcL 211
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRL--PGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGGlkpSSETP-------L 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787   212 HSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNA--LLVGDMAYYDfNGEMEQEADRINLQKCLGPTCKILVLRN 289
Cdd:pfam00596  72 HLAIYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAadFLGGDIPIIP-YYTPGTEELGERIAEALGGDRKAVLLRN 150

                         170       180
                  ....*....|....*....|....*...
gi 89276787   290 HGVVALGDTVEEAFYKIFHLQAACEIQV 317
Cdd:pfam00596 151 HGLLVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 137-317 4.20e-48

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 165.50  E-value: 4.20e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787    137 ISSVYRLLDLYGWAQLSDTYVTLRVsKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSscFPVDTTGFCLHSAIY 216
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARV-GEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGG--GPKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787    217 AARPDVRCIIHLHTPATAAVSAMKW--GLLPVSHNALLVG-DMAYYDFNGEMEQEADRI-NLQKCLGPT---CKILVLRN 289
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALGKplPLLPTEQAAAFLGgEIPYAPYAGPGTELAEEGaELAEALAEAlpdRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 89276787    290 HGVVALGDTVEEAFYKIFHLQAACEIQV 317
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 130-338 3.05e-47

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 163.85  E-value: 3.05e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 130 ERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVskEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSscfpVDTTGF 209
Cdd:COG0235   3 EEELREELAAAGRRLARRGLVDGTAGNISVRL--DDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGDL----KPSSET 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787 210 CLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHN--ALLVGDMAYYDFNG-EMEQEADRInlQKCLGpTCKILV 286
Cdd:COG0235  77 PLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEQTeaAAFLGDVPVVPYAGpGTEELAEAI--AEALG-DRPAVL 153

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 89276787 287 LRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALsSAGGVENLILLEQEKHR 338
Cdd:COG0235 154 LRNHGVVVWGKDLAEAFDRAEVLEEAARIQLLAL-ALGGPLVLSDEEIDKLA 204
PRK06661 PRK06661
hypothetical protein; Provisional
 141-374 1.23e-36

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 136.11  E-value: 1.23e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  141 YRLLDLYGWAQLSDTYVTLRvSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSscFPVDTTGFCLHSAIYAARP 220
Cdd:PRK06661  11 YRIMAYLSLDDHTYTHLSAR-PKNADFYYIYPFGLRFEEVTTENLLKVSLDGQILEGEE--YQYNKTGYFIHGSIYKTRP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  221 DVRCIIHLHTPATAAVSAMKWGLLPVSHNAL-LVGDMAYYDFNG---EMEQEADRinLQKCLGPTcKILVLRNHGVVALG 296
Cdd:PRK06661  88 DISAIFHYHTPASIAVSALKCGLLPISQWALhFYDRISYHNYNSlalDADKQSSR--LVNDLKQN-YVMLLRNHGAITCG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  297 DTVEEAFYKIFHLQAACEIQVSALSSAggvenlillEQEKHRPhevgSVQWAGSTFGPMQ--KSRLGEHEFEALMRMLDN 374
Cdd:PRK06661 165 KTIHEAMFYTYHLEQACKTQCLLNSTK---------KQELIIP----SVEICKKTVKDLLsfEEDLGKRDWAAWLRLIKM 231
PRK06208 PRK06208
class II aldolase/adducin family protein;
130-354 2.20e-27

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 111.62  E-value: 2.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  130 ERLMR-CKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEkGSscFPVDTTG 208
Cdd:PRK06208  39 ERLHRkQRLAAAFRLFARFGFDEGLAGHITARDPELPDHFWVNPLGVHFSQIKVSDLLLVDHDGEVVE-GD--RPLNRAA 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  209 FCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNAL-LVGDMAYYD-FNGEM--EQEADRInlQKCLGPTcKI 284
Cdd:PRK06208 116 FAIHSAIHEARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACaFYEDHALFDdFTGVVvdTSEGRRI--AAALGTH-KA 192

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  285 LVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVsaLSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGP 354
Cdd:PRK06208 193 VILQNHGLLTVGPSVDAAAWWFIALERACQTQL--LAEAAGPPQPIDHETARHTRSQVGSEYGGWFNFQP 260
PRK07490 PRK07490
hypothetical protein; Provisional
 130-322 1.00e-23

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 100.18  E-value: 1.00e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  130 ERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNilgevvEKGSSCFP----VD 205
Cdd:PRK07490   8 EEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKQFLLNPKWKHFSRIRASDLLLLD------ADDPSTAErpdvPD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  206 TTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWG-LLPVSHNALLVGDMAYYDFN-GEMEQEADRINLQKCLGpTCK 283
Cdd:PRK07490  82 ATAWAIHGQIHRRLPHARCVMHVHSVYATALACLADPtLPPIDQNTARFFNRVAVDTLyGGMALEEEGERLAGLLG-DKR 160

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 89276787  284 ILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSS 322
Cdd:PRK07490 161 RLLMGNHGVLVTGDTVAEAFDDLYYFERACQTYITALST 199
PRK06486 PRK06486
aldolase;
165-373 6.00e-23

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 98.25  E-value: 6.00e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  165 QDHFLISPKGVSCSEVTASSLIKVNILGEVVEkGSScfPVDTTGFCLHSAIYAARPDVRCIIHLHTP-ATAAVSAMKWGL 243
Cdd:PRK06486  59 DDLFLVNPYGYAFSEITASDLLICDFDGNVLA-GRG--EPEATAFFIHARIHRAIPRAKAAFHTHMPyATALSLTEGRPL 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  244 LPVSHNAllvgdMAYY-------DFNGEM--EQEADRInlQKCLGpTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACE 314
Cdd:PRK06486 136 TTLGQTA-----LKFYgrtavdeDYNGLAldAAEGDRI--ARAMG-DADIVFLKNHGVMVCGPRIAEAWDDLYYLERACE 207

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 89276787  315 IQVSALSSAGGVenlilleqeKHRPHEVgsvqwAGSTFGPMqksRLGEHE-----FEALMRMLD 373
Cdd:PRK06486 208 VQVLAMSTGRPL---------VPVDPAI-----AAAVARQM---REGDREsarlhLEALRRTLD 254
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 150-338 1.31e-14

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 73.90  E-value: 1.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  150 AQLSDTYVTLRVskeqdhflispkGVSCSEVTASSLIKVNILGEVVEkGSScFPVDTTGFclHSAIYAARPDVRCIIHLH 229
Cdd:PRK07090  59 AEAPGTYYTQRL------------GLGFDEITASNLLLVDEDLNVLD-GEG-MPNPANRF--HSWIYRARPDVNCIIHTH 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  230 TPATAAVSAMKWGLLpVSH--NALLVGDMAYY---------DFNGEMEQEAdrinlqkcLGPTCKILvLRNHGVVALGDT 298
Cdd:PRK07090 123 PPHVAALSMLEVPLV-VSHmdTCPLYDDCAFLkdwpgvpvgNEEGEIISAA--------LGDKRAIL-LSHHGQLVAGKS 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 89276787  299 VEEAFYKIFHLQAACEIQVSAlSSAGGVENLI-LLEQEKHR 338
Cdd:PRK07090 193 IEEACVLALLIERAARLQLLA-MAAGPIKPIPpELAREAHD 232
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 157-302 4.29e-10

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 60.02  E-value: 4.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  157 VTLRVsKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEkGSSCFPVDTTGfclHSAIYAARPDVRCIIHLHTP-ATA- 234
Cdd:PRK06557  35 VSARD-PGTDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVE-GDLKPSSDTAS---HLYVYRHMPDVGGVVHTHSTyATAw 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  235 ---------AVSAMK---WGLLPVSHNAlLVGDmayydfngemeqeaDRIN---LQKCLGPTCKILVLRNHGVVALGDTV 299
Cdd:PRK06557 110 aargepipcVLTAMAdefGGPIPVGPFA-LIGD--------------EAIGkgiVETLKGGRSPAVLMQNHGVFTIGKDA 174


                 ...
gi 89276787  300 EEA 302
Cdd:PRK06557 175 EDA 177
PRK08130 PRK08130
putative aldolase; Validated
 167-304 1.62e-09

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 57.96  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  167 HFLISPKGVSCSEVTASSLIKVNILGEVVE--KGSSCFPvdttgfcLHSAIYAARPDVRCIIHLHTPATAAVSamkwgLL 244
Cdd:PRK08130  38 GWLVTPTGSCLGRLDPARLSKVDADGNWLSgdKPSKEVP-------LHRAIYRNNPECGAVVHLHSTHLTALS-----CL 105

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 89276787  245 PV--SHNAL---------LVGDMA---YY---DfngemEQEADRInlqKCLGPTCKILVLRNHGVVALGDTVEEAFY 304
Cdd:PRK08130 106 GGldPTNVLppftpyyvmRVGHVPlipYYrpgD-----PAIAEAL---AGLAARYRAVLLANHGPVVWGSSLEAAVN 174
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
163-315 5.56e-09

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 56.30  E-value: 5.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  163 KEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEkGSScfpVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWG 242
Cdd:PRK06833  35 REQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVE-GER---KPSSELDMHLIFYRNREDINAIVHTHSPYATTLACLGWE 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  243 LLPVSHNALLVGD---MAYYDFNG--EMEQEA-----DRinlqkclgptcKILVLRNHGVVALGDTVEEAFYKIFHLQAA 312
Cdd:PRK06833 111 LPAVHYLIAVAGPnvrCAEYATFGtkELAENAfeameDR-----------RAVLLANHGLLAGANNLKNAFNIAEEIEFC 179


                 ...
gi 89276787  313 CEI 315
Cdd:PRK06833 180 AEI 182
PRK08333 PRK08333
aldolase;
166-305 1.03e-08

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 55.21  E-value: 1.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  166 DHFLISPKGVSCSEVTASSLIKVNILGEVVekgSSCFPvdTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLP 245
Cdd:PRK08333  34 NLVFIKATGSVMDELTREQVAVIDLNGNQL---SSVRP--SSEYRLHLAVYRNRPDVRAIAHLHPPYSIVASTLLEEELP 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 89276787  246 V--SHNALLVGDMAYYDFngemeQEADRINLQKCLGPTCK---ILVLRNHGVVALGDTVEEAFYK 305
Cdd:PRK08333 109 IitPEAELYLKKIPILPF-----RPAGSVELAEQVAEAMKeydAVIMERHGIVTVGRSLREAFYK 168
PRK08660 PRK08660
aldolase;
165-315 2.62e-08

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 53.81  E-value: 2.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  165 QDHFLISPKGVSCSEVTASSLIKVNIL--GEVVEKGSSCFPVdttgfclHSAIYAaRPDVRCIIHLHTPATAAVSAMKWG 242
Cdd:PRK08660  30 GDGLLITRTGSMLDEITEGDVIEVGIDddGSVDPLASSETPV-------HRAIYR-RTSAKAIVHAHPPYAVALSLLEDE 101

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 89276787  243 LLPV-SHNALLVGDMAYYDFNGEMEQEADriNLQKCLGPTcKILVLRNHGVVALGDTVEEAFYKIFHLQAACEI 315
Cdd:PRK08660 102 IVPLdSEGLYFLGTIPVVGGDIGSGELAE--NVARALSEH-KGVVVRGHGTFAIGKTLEEAYIYTSQLEHSCKV 172
PRK05874 PRK05874
L-fuculose-phosphate aldolase; Validated
 167-314 4.30e-05

L-fuculose-phosphate aldolase; Validated


Pssm-ID: 102036 [Multi-domain]  Cd Length: 217  Bit Score: 45.02  E-value: 4.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  167 HFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPvdTTGFCLHSAIYAARPDVRCIIHLHtPATAAVSAMKWGLLPV 246
Cdd:PRK05874  39 NVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKDGRSP--STELNLHLACYRAFDDIGSVIHSH-PVWATMFAVAHEPIPA 115

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 89276787  247 SHNALLV---GDMAYYDFNGEMEQEADRINLQKCLGPTCKILVlrNHGVVALGDTVEeafyKIFHLQAACE 314
Cdd:PRK05874 116 CIDEFAIycgGDVRCTEYAASGTPEVGRNAVRALEGRAAALIA--NHGLVAVGPRPD----QVLRVTALVE 180
araD PRK13145
L-ribulose-5-phosphate 4-epimerase; Provisional
 161-304 4.74e-05

L-ribulose-5-phosphate 4-epimerase; Provisional


Pssm-ID: 183870 [Multi-domain]  Cd Length: 234  Bit Score: 44.82  E-value: 4.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  161 VSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVE---KGSSCFPVdttgfclHSAIYAARPDVRCIIHLHTpaTAAVS 237
Cdd:PRK13145  33 VCRELGRIVIKPSGVDYDELTPENMVVTDLDGNVVEgdlNPSSDLPT-------HVELYKAWPEVGGIVHTHS--TEAVG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  238 AMKWGL-LP---VSHNALLVGD------MAYYDFNGEMEQEADRINLQ----KCLGP-TCKILVLRNHGVVALGDTVEEA 302
Cdd:PRK13145 104 WAQAGRdIPfygTTHADYFYGPipcarsLTKDEVNGAYEKETGSVIIEefekRGLDPmAVPGIVVRNHGPFTWGKNPEQA 183


                 ..
gi 89276787  303 FY 304
Cdd:PRK13145 184 VY 185
araD PRK08193
L-ribulose-5-phosphate 4-epimerase AraD;
161-234 1.09e-04

L-ribulose-5-phosphate 4-epimerase AraD;


Pssm-ID: 236181  Cd Length: 231  Bit Score: 43.67  E-value: 1.09e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 89276787  161 VSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVE---KGSScfpvDT-TgfclHSAIYAARPDVRCIIHLHTP-ATA 234
Cdd:PRK08193  32 IDRERGLFVIKPSGVDYDKMTAEDMVVVDLEGNVVEgklKPSS----DTpT----HLVLYKAFPEIGGIVHTHSRhATA 102
sgaE PRK12348
L-ribulose-5-phosphate 4-epimerase; Reviewed
 141-304 1.69e-04

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183460  Cd Length: 228  Bit Score: 43.25  E-value: 1.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  141 YRLLdLYGWAQLSDtyvtlrVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVE---KGSScfpvDTTgfcLHSAIYA 217
Cdd:PRK12348  18 YGLV-TFTWGNVSA------IDRERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEgeyRPSS----DTA---THLELYR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  218 ARPDVRCIIHLHTP-ATA-AVSAMKWGLLPVSHNALLVGD------MAYYDFNGEMEQEADRINLQKcLGPTCKI----L 285
Cdd:PRK12348  84 RYPSLGGIVHTHSThATAwAQAGLAIPALGTTHADYFFGDipctrgLSEEEVQGEYELNTGKVIIET-LGNAEPLhtpgI 162

                        170
                 ....*....|....*....
gi 89276787  286 VLRNHGVVALGDTVEEAFY 304
Cdd:PRK12348 163 VVYQHGPFAWGKDAHDAVH 181
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
165-319 3.93e-04

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 42.03  E-value: 3.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  165 QDHFLISPKGVSCSEVTASSLIKVNILGEVvEKGSscFPVDTTGFclHSAIYAARPDVRCIIHLHTPATAAVSAMKWGlL 244
Cdd:PRK08087  35 QDGMLITPTGIPYEKLTESHIVFVDGNGKH-EEGK--LPSSEWRF--HMAAYQTRPDANAVVHNHAVHCTAVSILNRP-I 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89276787  245 PVSHNALLV--GD----MAYYDFNGEMEQEADRINLQKclgptCKILVLRNHGVVALGDTVEEAfykifhLQAACEIQVS 318
Cdd:PRK08087 109 PAIHYMIAAagGNsipcAPYATFGTRELSEHVALALKN-----RKATLLQHHGLIACEVNLEKA------LWLAHEVEVL 177


                 .
gi 89276787  319 A 319
Cdd:PRK08087 178 A 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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