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Conserved domains on  [gi|118572613|ref|NP_057417|]
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serine/arginine repetitive matrix protein 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
 39-102 1.21e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


:

Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 118.97  E-value: 1.21e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118572613   39 EEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375     1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
2195-2452 2.21e-07

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 56.78  E-value: 2.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2195 PPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAI---PTAVNLADSRTPAAAAAMNLA 2271
Cdd:PRK07003  360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAaaaAATRAEAPPAAPAPPATADRG 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN 2351
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2352 iagSRTAAALAPASLTS-----ARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
Cdd:PRK07003  520 ---DAPAAAAPPAPEARpptpaAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQV 596

                         250       260       270
                  ....*....|....*....|....*....|..
gi 118572613 2427 PSSRMGQAPSQSLL------PPAQDQPRSPVP 2452
Cdd:PRK07003  597 PTPRARAATGDAPPngaaraEQAAESRGAPPP 628
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
313-411 6.02e-06

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14971:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 614  Bit Score: 51.70  E-value: 6.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  313 PGTTSTQRPSSPetATKQPSSPYEDKdkdkkekSATRPSPSPERSSTGPEPPAPTPllAERHGGSPQPLATTPLSQEPVN 392
Cdd:PRK14971  370 SGGRGPKQHIKP--VFTQPAAAPQPS-------AAAAASPSPSQSSAAAQPSAPQS--ATQPAGTPPTVSVDPPAAVPVN 438

                          90
                  ....*....|....*....
gi 118572613  393 PPSEASPTRDRSPPKSPEK 411
Cdd:PRK14971  439 PPSTAPQAVRPAQFKEEKK 457
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 293-600 2.61e-05

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 2.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSS----PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
Cdd:PHA03307   81 ANESRSTPTWSLSTLAPASPAREGSPTPPGPsspdPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPA 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPeklpqssssessppsPQPTKVSRHASSSPESPKPAPAPG 448
Cdd:PHA03307  161 AVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAA---------------ASPRPPRRSSPISASASSPAPAPG 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  449 SHREISSSPTSKNRSHGRAKRDKSH--------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSaq 520
Cdd:PHA03307  226 RSAADDAGASSSDSSSSESSGCGWGpenecplpRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP-- 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600
Cdd:PHA03307  304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAG 383
 
Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
 39-102 1.21e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 118.97  E-value: 1.21e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118572613   39 EEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375     1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
cwf21 pfam08312
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ...
 58-101 1.54e-07

cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices.


Pssm-ID: 462421 [Multi-domain]  Cd Length: 44  Bit Score: 49.73  E-value: 1.54e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 118572613    58 LDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEK 101
Cdd:pfam08312    1 LEHERKREIEVKVLELRDELEEQGLSEEEIEEKVDELRKKLLAE 44
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2195-2452 2.21e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 56.78  E-value: 2.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2195 PPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAI---PTAVNLADSRTPAAAAAMNLA 2271
Cdd:PRK07003  360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAaaaAATRAEAPPAAPAPPATADRG 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN 2351
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2352 iagSRTAAALAPASLTS-----ARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
Cdd:PRK07003  520 ---DAPAAAAPPAPEARpptpaAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQV 596

                         250       260       270
                  ....*....|....*....|....*....|..
gi 118572613 2427 PSSRMGQAPSQSLL------PPAQDQPRSPVP 2452
Cdd:PRK07003  597 PTPRARAATGDAPPngaaraEQAAESRGAPPP 628
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
313-411 6.02e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 51.70  E-value: 6.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  313 PGTTSTQRPSSPetATKQPSSPYEDKdkdkkekSATRPSPSPERSSTGPEPPAPTPllAERHGGSPQPLATTPLSQEPVN 392
Cdd:PRK14971  370 SGGRGPKQHIKP--VFTQPAAAPQPS-------AAAAASPSPSQSSAAAQPSAPQS--ATQPAGTPPTVSVDPPAAVPVN 438

                          90
                  ....*....|....*....
gi 118572613  393 PPSEASPTRDRSPPKSPEK 411
Cdd:PRK14971  439 PPSTAPQAVRPAQFKEEKK 457
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 293-600 2.61e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 2.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSS----PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
Cdd:PHA03307   81 ANESRSTPTWSLSTLAPASPAREGSPTPPGPsspdPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPA 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPeklpqssssessppsPQPTKVSRHASSSPESPKPAPAPG 448
Cdd:PHA03307  161 AVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAA---------------ASPRPPRRSSPISASASSPAPAPG 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  449 SHREISSSPTSKNRSHGRAKRDKSH--------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSaq 520
Cdd:PHA03307  226 RSAADDAGASSSDSSSSESSGCGWGpenecplpRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP-- 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600
Cdd:PHA03307  304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAG 383
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 2271-2527 2.91e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 46.11  E-value: 2.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  2271 ASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAnlvgPRSAHATAPV 2350
Cdd:pfam17823  129 SLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSA----PTTAASSAPA 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  2351 NIAGSRTAAALAPASLT-SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSS 2429
Cdd:pfam17823  205 TLTPARGISTAATATGHpAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAK 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  2430 RM-GQAPSQSLLPPAQDQPRSPVPSAFSDQ-----------SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497
Cdd:pfam17823  285 HMpSDTMARNPAAPMGAQAQGPIIQVSTDQpvhntageptpSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVP 364

                          250       260       270
                   ....*....|....*....|....*....|
gi 118572613  2498 APgvPHSDVGEPPASTGAQQPSALAALQPA 2527
Cdd:pfam17823  365 VL--HTSMIPEVEATSPTTQPSPLLPTQGA 392
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 314-527 5.61e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.21  E-value: 5.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613   314 GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP---SPERSSTGPEPPAPTPLLAER-----------HGGSPQ 379
Cdd:pfam05109  480 GTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPnatSPTPAVTTPTPNATSPTLGKTsptsavttptpNATSPT 559

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613   380 PLATTPLSQEPVNPPSEASPTRDRSPP----KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455
Cdd:pfam05109  560 PAVTTPTPNATIPTLGKTSPTSAVTTPtpnaTSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSS 639

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 118572613   456 S-------PTSKNRSHGRAKRDKSHSHTPsrrMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527
Cdd:pfam05109  640 StssmslrPSSISETLSPSTSDNSTSHMP---LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNS 715
 
Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
 39-102 1.21e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 118.97  E-value: 1.21e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118572613   39 EEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375     1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
cwf21_SRRM3 cd21376
cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins; Serine ...
 37-102 1.36e-23

cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins; Serine/arginine repetitive matrix protein 3 (SRRM3) may play a role in regulating breast cancer cell invasiveness. It may also be involved in RYBP-mediated breast cancer progression. SRRM3 contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410602 [Multi-domain]  Cd Length: 68  Bit Score: 96.35  E-value: 1.36e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118572613   37 KGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21376     1 KSEEEIKKLDAALVKKPNREILDHERKRKVELKCMEMQELMEEQGYTEEEIRQKVSTFRQMLMEKE 66
cwf21_SRRM2-like cd21373
cwf21 domain found in serine/arginine repetitive matrix proteins, SRRM2, SRRM3 and similar ...
 53-102 6.29e-17

cwf21 domain found in serine/arginine repetitive matrix proteins, SRRM2, SRRM3 and similar proteins; This subfamily includes SRRM2 and SRRM3, both of which contain a cwf21 domain at the N-terminus. SRRM2, also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803), is required for pre-mRNA splicing as component of the spliceosome. SRRM3 may play a role in regulating breast cancer cell invasiveness. It may be involved in RYBP-mediated breast cancer progression. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410600 [Multi-domain]  Cd Length: 50  Bit Score: 76.46  E-value: 6.29e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 118572613   53 PNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21373     1 PNKEILDHERKRKIEVKCLELEDLLEEQGYTEEEIQAKVDEYRALLLEKD 50
cwf21 cd21369
cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the ...
 55-101 4.44e-10

cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevents its binding to Prp8. The domain is composed of two alpha helices. Proteins containing the cwf21 domain include complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. This domain family also includes U2-associated protein SR140 from Eumetazoa, protein RRC1, and similar proteins from plants.


Pssm-ID: 410596 [Multi-domain]  Cd Length: 48  Bit Score: 57.09  E-value: 4.44e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 118572613   55 PDILDHERKRRVELRCLELEEMMEEQG-YEEQQIQEKVATFRLMLLEK 101
Cdd:cd21369     1 MDEEKRAKKREIELKVMELRDELEEQGrKPEQQIQEKVEHYRDKLLQR 48
cwf21_CWC21-like cd21372
cwf21 domain found in fungal complexed with CEF1 protein 21 (CWC21) and similar proteins; This ...
 54-102 4.56e-10

cwf21 domain found in fungal complexed with CEF1 protein 21 (CWC21) and similar proteins; This subfamily includes complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. Both CWC21 and CWF21 are pre-mRNA-splicing factors that may function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome, together with ISY1. SRRM2 is required for pre-mRNA splicing as a component of the spliceosome. SRRM3 may play a role in regulating breast cancer cell invasiveness. It may be involved in RYBP-mediated breast cancer progression. Members of this family contain a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410599 [Multi-domain]  Cd Length: 49  Bit Score: 57.10  E-value: 4.56e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 118572613   54 NPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21372     1 DKEILEHERKRQIELKCLELRDELEDEGLSEEEIEEKVDELREKLLKEL 49
cwf21 pfam08312
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ...
 58-101 1.54e-07

cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices.


Pssm-ID: 462421 [Multi-domain]  Cd Length: 44  Bit Score: 49.73  E-value: 1.54e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 118572613    58 LDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEK 101
Cdd:pfam08312    1 LEHERKREIEVKVLELRDELEEQGLSEEEIEEKVDELRKKLLAE 44
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2195-2452 2.21e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 56.78  E-value: 2.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2195 PPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAI---PTAVNLADSRTPAAAAAMNLA 2271
Cdd:PRK07003  360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAaaaAATRAEAPPAAPAPPATADRG 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN 2351
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2352 iagSRTAAALAPASLTS-----ARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
Cdd:PRK07003  520 ---DAPAAAAPPAPEARpptpaAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQV 596

                         250       260       270
                  ....*....|....*....|....*....|..
gi 118572613 2427 PSSRMGQAPSQSLL------PPAQDQPRSPVP 2452
Cdd:PRK07003  597 PTPRARAATGDAPPngaaraEQAAESRGAPPP 628
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2189-2605 3.19e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.49  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2189 SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSR-TPAAAAA 2267
Cdd:PHA03247 2567 SVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPdPHPPPTV 2646

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2268 MNLASPRTAVAPSAVNL----ADPRTPTAPAVNLAGARTPAALAAL-SLTGSGTPPTAANYPSSSRTPQAPASANLVGPR 2342
Cdd:PHA03247 2647 PPPERPRDDPAPGRVSRprraRRLGRAAQASSPPQRPRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPA 2726

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2343 SAHATAPVNIAGSRT----AAALAPASLTSARMAPALSGANL-TSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
Cdd:PHA03247 2727 AARQASPALPAAPAPpavpAGPATPGGPARPARPPTTAGPPApAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD 2806

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2418 RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP-VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496
Cdd:PHA03247 2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPpPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRL 2886

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2497 PAPGVPHSdvgeppastgaQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDsegsslPVQPEVAL 2576
Cdd:PHA03247 2887 ARPAVSRS-----------TESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP------PLAPTTDP 2949

                         410       420
                  ....*....|....*....|....*....
gi 118572613 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
Cdd:PHA03247 2950 AGAGEPSGAVPQPWLGALVPGRVAVPRFR 2978
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2030-2502 5.83e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 5.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2030 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPrtargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2110 nSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSrtpmsvlqqagGSMMDGPGPRIPDHQRTsvpenhaqsrialalTAIS 2189
Cdd:PHA03247 2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2190 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTPAIPTAvnladsrTPAAAAAMN 2269
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2270 LASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAP 2349
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGD 2861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2350 VniagSRTAAALAPASLTSARMAPALSganltspRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSqsrmtseraPSPSS 2429
Cdd:PHA03247 2862 V----RRRPPSRSPAAKPAAPARPPVR-------RLARPAVSRSTESFALPPDQPERPPQPQAPPP---------PQPQP 2921

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 118572613 2430 RMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Cdd:PHA03247 2922 QPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTP 2994
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
313-411 6.02e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 51.70  E-value: 6.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  313 PGTTSTQRPSSPetATKQPSSPYEDKdkdkkekSATRPSPSPERSSTGPEPPAPTPllAERHGGSPQPLATTPLSQEPVN 392
Cdd:PRK14971  370 SGGRGPKQHIKP--VFTQPAAAPQPS-------AAAAASPSPSQSSAAAQPSAPQS--ATQPAGTPPTVSVDPPAAVPVN 438

                          90
                  ....*....|....*....
gi 118572613  393 PPSEASPTRDRSPPKSPEK 411
Cdd:PRK14971  439 PPSTAPQAVRPAQFKEEKK 457
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2251-2460 1.08e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 51.03  E-value: 1.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2251 PTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSltgsgtpptAANYPSSSRTP 2330
Cdd:PRK12323  375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALA---------AARQASARGPG 445

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2331 QAPASANLVGPRSAHATAPVnIAGSRTAAALAPASltSARMAPALSGAnlTSPRVPLSAYERVSGRTSPPLLDRARSRTP 2410
Cdd:PRK12323  446 GAPAPAPAPAAAPAAAARPA-AAGPRPVAAAAAAA--PARAAPAAAPA--PADDDPPPWEELPPEFASPAPAQPDAAPAG 520

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 118572613 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460
Cdd:PRK12323  521 WVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASA 570
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 293-600 2.61e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 2.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSS----PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
Cdd:PHA03307   81 ANESRSTPTWSLSTLAPASPAREGSPTPPGPsspdPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPA 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPeklpqssssessppsPQPTKVSRHASSSPESPKPAPAPG 448
Cdd:PHA03307  161 AVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAA---------------ASPRPPRRSSPISASASSPAPAPG 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  449 SHREISSSPTSKNRSHGRAKRDKSH--------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSaq 520
Cdd:PHA03307  226 RSAADDAGASSSDSSSSESSGCGWGpenecplpRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP-- 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600
Cdd:PHA03307  304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAG 383
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 231-540 9.55e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 48.24  E-value: 9.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAkthTTALAGRSPSPASGRRGEGDAPF 310
Cdd:PHA03307  125 SPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSS---PEETARAPSSPPAEPPPSTPPAA 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  311 SEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPErSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP 390
Cdd:PHA03307  202 ASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSG-CGWGPENECPLPRPAPITLPTRIWEASGWNGPSS 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  391 VNPP-SEASPTRDRSPPKSPEKlpqssssESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREiSSSPTSKNRSHGRakr 469
Cdd:PHA03307  281 RPGPaSSSSSPRERSPSPSPSS-------PGSGPAPSSPRASSSSSSSRESSSSSTSSSSESS-RGAAVSPGPSPSR--- 349

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118572613  470 dkshSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
Cdd:PHA03307  350 ----SPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSP 416
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2159-2449 2.13e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.77  E-value: 2.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2159 GPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAA 2238
Cdd:PRK07003  367 APGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGD 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2239 AMNLASARTPAIPTAVNLADSRTPAAAAAMNlASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP 2318
Cdd:PRK07003  447 APVPAKANARASADSRCDERDAQPPADSGSA-SAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAA 525

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2319 TAanyPSSSRTPQAPASANLVGpRSAHATAPVNI---AGSRTaaalapaSLTSARMAPALSGANLTSPRVPLSAYERVSG 2395
Cdd:PRK07003  526 AP---PAPEARPPTPAAAAPAA-RAGGAAAALDVlrnAGMRV-------SSDRGARAAAAAKPAAAPAAAPKPAAPRVAV 594

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 118572613 2396 RTSPPlldrarsRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRS 2449
Cdd:PRK07003  595 QVPTP-------RARAATGDAPPNGAARAEQAAESRGAPPPWEDIPPDDYVPLS 641
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 2271-2527 2.91e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 46.11  E-value: 2.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  2271 ASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAnlvgPRSAHATAPV 2350
Cdd:pfam17823  129 SLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSA----PTTAASSAPA 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  2351 NIAGSRTAAALAPASLT-SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSS 2429
Cdd:pfam17823  205 TLTPARGISTAATATGHpAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAK 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  2430 RM-GQAPSQSLLPPAQDQPRSPVPSAFSDQ-----------SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497
Cdd:pfam17823  285 HMpSDTMARNPAAPMGAQAQGPIIQVSTDQpvhntageptpSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVP 364

                          250       260       270
                   ....*....|....*....|....*....|
gi 118572613  2498 APgvPHSDVGEPPASTGAQQPSALAALQPA 2527
Cdd:pfam17823  365 VL--HTSMIPEVEATSPTTQPSPLLPTQGA 392
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2191-2411 4.36e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 4.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2191 GTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNL 2270
Cdd:PRK12323  370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2271 ASPRTAVAPSAVN---LADPRTPTAPAVNLAGARTPAALAAlsltgsgtpPTAANYPSSSRTPQAPASANLVGPRSAHAT 2347
Cdd:PRK12323  450 PAPAPAAAPAAAArpaAAGPRPVAAAAAAAPARAAPAAAPA---------PADDDPPPWEELPPEFASPAPAQPDAAPAG 520

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118572613 2348 APVNiAGSRTAAALAPASLTSARMAPALSGAnltsPRVPLSAYERVSGRtsPPllDRARSRTPP 2411
Cdd:PRK12323  521 WVAE-SIPDPATADPDDAFETLAPAPAAAPA----PRAAAATEPVVAPR--PP--RASASGLPD 575
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2193-2601 4.38e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 4.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2193 ARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASriPAASAAAMNLASARTPAIPTAVNLADSRTPAaaaamnlas 2272
Cdd:PRK07764  395 AAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPA--PAPAPAPAPPSPAGNAPAGGAPSPPPAAAPS--------- 463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2273 prtavapsavnlADPRTPTAPAVNLAGARTPAALAAlsltgsGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNI 2352
Cdd:PRK07764  464 ------------AQPAPAPAAAPEPTAAPAPAPPAA------PAPAAAPAAPAAPAAPAGADDAATLRERWPEILAAVPK 525

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2353 AGSRTAAALAPA-------------SLTSARMAPALSGANltSPRVPLSAYERVSGRTSPPlldRARSRTPPSAPSQSRm 2419
Cdd:PRK07764  526 RSRKTWAILLPEatvlgvrgdtlvlGFSTGGLARRFASPG--NAEVLVTALAEELGGDWQV---EAVVGPAPGAAGGEG- 599

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQP-RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498
Cdd:PRK07764  600 PPAPASSGPPEEAARPAAPAAPAAPAAPaPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPA 679

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2499 PGVPHSDVGEPPASTGAQQPSALAAlqPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Cdd:PRK07764  680 APPPAPAPAAPAAPAGAAPAQPAPA--PAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQ 757

                         410       420
                  ....*....|....*....|...
gi 118572613 2579 VPSPTPAPKEAVREGRPPEPTPA 2601
Cdd:PRK07764  758 PPPPPAPAPAAAPAAAPPPSPPS 780
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2313-2523 4.71e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 4.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2313 GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVniAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYER 2392
Cdd:PRK12323  370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPA--AAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2393 VSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSrcliaqttPVAGS 2472
Cdd:PRK12323  448 PAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQP--------DAAPA 519

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 118572613 2473 QSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Cdd:PRK12323  520 GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASA 570
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2198-2601 6.41e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.36  E-value: 6.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2198 SMSAAGLAARMSQVPAPVPLM-----SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272
Cdd:PRK07764  368 SDDERGLLARLERLERRLGVAggagaPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGN 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2273 PRTAVAPSAVNLADPRTPTAPAVnlAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNI 2352
Cdd:PRK07764  448 APAGGAPSPPPAAAPSAQPAPAP--AAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPEILAAVPK 525

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2353 AGSRTAAALAPA-------------SLTSARMAPALSGANltSPRVPLSAYERVSGRTSPPlldRARSRTPPSAPSQSRm 2419
Cdd:PRK07764  526 RSRKTWAILLPEatvlgvrgdtlvlGFSTGGLARRFASPG--NAEVLVTALAEELGGDWQV---EAVVGPAPGAAGGEG- 599

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQP-RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498
Cdd:PRK07764  600 PPAPASSGPPEEAARPAAPAAPAAPAAPaPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPA 679

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2499 PGVPHSDVGEPPASTGAQQPSALAAlqPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Cdd:PRK07764  680 APPPAPAPAAPAAPAGAAPAQPAPA--PAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQ 757

                         410       420
                  ....*....|....*....|....*...
gi 118572613 2579 VPSPTPAPKEAV-----REGRPPEPTPA 2601
Cdd:PRK07764  758 PPPPPAPAPAAApaaapPPSPPSEEEEM 785
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 287-581 8.52e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 8.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  287 HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
Cdd:PHA03307   49 ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPP 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  367 TP----LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPP-----------KSPEKLPQSSSSESSPPSPQPTKVS 431
Cdd:PHA03307  129 SPapdlSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalplsspeetaRAPSSPPAEPPPSTPPAAASPRPPR 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  432 RHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSH--------SHTPSRRMGRSRSPATAKRGRSRSRTPTKR 503
Cdd:PHA03307  209 RSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGpenecplpRPAPITLPTRIWEASGWNGPSSRPGPASSS 288

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 118572613  504 GHSRSRSPQWRRSRSaqRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARR 581
Cdd:PHA03307  289 SSPRERSPSPSPSSP--GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSS 364
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2151-2377 9.76e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.87  E-value: 9.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2151 QAGGSMMDGPGPRIPDHQRT--SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSqvPAPVPLMSLRTAPAANL 2228
Cdd:PRK12323  367 QSGGGAGPATAAAAPVAQPApaAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRS--PAPEALAAARQASARGP 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2229 ASRIPAASAAAMnlasarTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAA 2308
Cdd:PRK12323  445 GGAPAPAPAPAA------APAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAP 518

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 118572613 2309 LSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVniagsrtaAALAPASLTSARMAPALSG 2377
Cdd:PRK12323  519 AGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPV--------VAPRPPRASASGLPDMFDG 579
PHA03247 PHA03247
large tegument protein UL36; Provisional
 162-540 1.01e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKkkkhrseseskkrkhRSPTPKSKRKSK 241
Cdd:PHA03247 2572 RPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAP---------------DPPPPSPSPAAN 2636

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  242 DKKRKRSRSTTPAPKSRRAhrstsadsasssdtSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDD--------------PAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPP 2702

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTR 401
Cdd:PHA03247 2703 PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRR 2782

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA---PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPS 478
Cdd:PHA03247 2783 LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAgplPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDV 2862

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118572613  479 RRMGRSRSPAT--AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
Cdd:PHA03247 2863 RRRPPSRSPAAkpAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPP 2926
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2178-2443 2.37e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 43.30  E-value: 2.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2178 QSRIALALTAISLGTARPPPSMSAAGlAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLA 2257
Cdd:PRK07003  413 KAAAAAAATRAEAPPAAPAPPATADR-GDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFE 491

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2258 DSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP-----TAANYPSSSRTPQA 2332
Cdd:PRK07003  492 PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAAldvlrNAGMRVSSDRGARA 571

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2333 -----PASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP---------RVPLSAYERVSGRTS 2398
Cdd:PRK07003  572 aaaakPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPpwedippddYVPLSADEGFGGPDD 651

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 118572613 2399 P--PLLDrarsrtppSAPSQSRMTSERAPSPSSRMGQAPsqslLPPA 2443
Cdd:PRK07003  652 GfvPVFD--------SGPDDVRVAPKPADAPAPPVDTRP----LPPA 686
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2312-2523 2.79e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 43.30  E-value: 2.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2312 TGSGTPPTAANYPSSSRTPQAPASAnlvGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYE 2391
Cdd:PRK07003  362 VTGGGAPGGGVPARVAGAVPAPGAR---AAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2392 RVSGRTSP-PLLDRARSRTPPSAPSQSRmtsERAPSPSSRMGQAPSQSLLPPAQDQPRSPVpsafsdqsrcliaqttpVA 2470
Cdd:PRK07003  439 GDDAADGDaPVPAKANARASADSRCDER---DAQPPADSGSASAPASDAPPDAAFEPAPRA-----------------AA 498

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 118572613 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Cdd:PRK07003  499 PSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAA 551
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 295-687 3.19e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 3.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  295 SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPyedkDKDKKEKSATRPSPSPERSSTGPEPPAPTPllaerh 374
Cdd:PHA03307   39 SQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTE----APANESRSTPTWSLSTLAPASPAREGSPTP------ 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  375 gGSPQPLATTPLSQEPVNPPSEASPTRdRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Cdd:PHA03307  109 -PGPSSPDPPPPTPPPASPPPSPAPDL-SEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAP 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  455 SSPTSKNRShgrakrdkshSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Cdd:PHA03307  187 SSPPAEPPP----------STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECP 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613  535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614
Cdd:PHA03307  257 LPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESS 336

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 118572613  615 SRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSrtpARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
Cdd:PHA03307  337 RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRP---SRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2183-2446 3.23e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2183 LALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASaaamnlasarTPAIPTAVNLADSRTP 2262
Cdd:PRK12323  361 LAFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAA----------AARAVAAAPARRSPAP 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2263 AAAAAMNLASPRTAVAPSAVnladprTPTAPAVNLAGARTPAAlaalsltGSGTPPTAANYPSSSRTPQAPASANLVGPR 2342
Cdd:PRK12323  431 EALAAARQASARGPGGAPAP------APAPAAAPAAAARPAAA-------GPRPVAAAAAAAPARAAPAAAPAPADDDPP 497

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2343 SAHATAPvniagsrtaaalAPASLTSARMAPALSGANLTSPRVPlsayervsgRTSPPLLDRARSRTPPSAPSQSRMTSE 2422
Cdd:PRK12323  498 PWEELPP------------EFASPAPAQPDAAPAGWVAESIPDP---------ATADPDDAFETLAPAPAAAPAPRAAAA 556

                         250       260
                  ....*....|....*....|....
gi 118572613 2423 RAPSPSSRMGQApSQSLLPPAQDQ 2446
Cdd:PRK12323  557 TEPVVAPRPPRA-SASGLPDMFDG 579
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 2333-2454 3.58e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2333 PASANLVGPRSAHATApvnIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYeRVSGRTSPPLLDRARSrTPPS 2412
Cdd:PRK14951  366 PAAAAEAAAPAEKKTP---ARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA-APPAPVAAPAAAAPAA-APAA 440

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 118572613 2413 APSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSA 2454
Cdd:PRK14951  441 APAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAA 482
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 314-527 5.61e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.21  E-value: 5.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613   314 GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP---SPERSSTGPEPPAPTPLLAER-----------HGGSPQ 379
Cdd:pfam05109  480 GTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPnatSPTPAVTTPTPNATSPTLGKTsptsavttptpNATSPT 559

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613   380 PLATTPLSQEPVNPPSEASPTRDRSPP----KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455
Cdd:pfam05109  560 PAVTTPTPNATIPTLGKTSPTSAVTTPtpnaTSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSS 639

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 118572613   456 S-------PTSKNRSHGRAKRDKSHSHTPsrrMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527
Cdd:pfam05109  640 StssmslrPSSISETLSPSTSDNSTSHMP---LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNS 715
PLN02321 PLN02321
2-isopropylmalate synthase
 2375-2486 9.19e-03

2-isopropylmalate synthase


Pssm-ID: 215182 [Multi-domain]  Cd Length: 632  Bit Score: 41.49  E-value: 9.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118572613 2375 LSGANLTSPRVPLSAYERVSGRTSPPlldRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP--VP 2452
Cdd:PLN02321    2 LRSPNLSSATAASPAKSLSAFTPAPT---RSSASSARFPAFLARPAAARSPSLASRASSALAASPSRPQVARRPRPeyIP 78

                          90       100       110
                  ....*....|....*....|....*....|....
gi 118572613 2453 SAFSDQSRCLIAQTTPVAGSQSLSsgavATTTSS 2486
Cdd:PLN02321   79 NRIDDPNYVRIFDTTLRDGEQSPG----ATLTSK 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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