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Conserved domains on  [gi|223278379|ref|NP_055994|]
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RRP12-like protein isoform 1 [Homo sapiens]

Protein Classification

RRP12 family protein( domain architecture ID 10548263)

RRP12 family protein similar to Saccharomyces cerevisiae ribosomal RNA-processing protein 12 (RRP12) that is required for nuclear export of both pre-40S and pre-60S ribosomal subunits

Gene Ontology:  GO:0003723|GO:0006364

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NUC173 pfam08161
NUC173 domain; This is the central domain of of novel family of hypothetical nucleolar ...
471-671 4.03e-94

NUC173 domain; This is the central domain of of novel family of hypothetical nucleolar proteins.


:

Pssm-ID: 462386  Cd Length: 202  Bit Score: 300.59  E-value: 4.03e-94
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223278379   471 MFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQA 550
Cdd:pfam08161    1 IAKALESLLSYKYQHAWKEVLNVLSALFEKLGKRSNPLLLPILKTLGDLRTSESFEFKKEADEVIGAAIRAMGPEVVLSI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223278379   551 VPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFC 630
Cdd:pfam08161   81 LPLNLDGPAGDIQPGRAWLLPLLRDNIRNTSLSFFKSEFLPLAEALFQKAKELEEAGKSVEAKIFETLVDQIWSLLPGFC 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 223278379   631 TRPTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITK 671
Cdd:pfam08161  161 NLPTDLKESFKSFAKLLGNLLYEQPELRPTICQALRTLVES 201
 
Name Accession Description Interval E-value
NUC173 pfam08161
NUC173 domain; This is the central domain of of novel family of hypothetical nucleolar ...
471-671 4.03e-94

NUC173 domain; This is the central domain of of novel family of hypothetical nucleolar proteins.


Pssm-ID: 462386  Cd Length: 202  Bit Score: 300.59  E-value: 4.03e-94
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223278379   471 MFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQA 550
Cdd:pfam08161    1 IAKALESLLSYKYQHAWKEVLNVLSALFEKLGKRSNPLLLPILKTLGDLRTSESFEFKKEADEVIGAAIRAMGPEVVLSI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223278379   551 VPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFC 630
Cdd:pfam08161   81 LPLNLDGPAGDIQPGRAWLLPLLRDNIRNTSLSFFKSEFLPLAEALFQKAKELEEAGKSVEAKIFETLVDQIWSLLPGFC 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 223278379   631 TRPTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITK 671
Cdd:pfam08161  161 NLPTDLKESFKSFAKLLGNLLYEQPELRPTICQALRTLVES 201
 
Name Accession Description Interval E-value
NUC173 pfam08161
NUC173 domain; This is the central domain of of novel family of hypothetical nucleolar ...
471-671 4.03e-94

NUC173 domain; This is the central domain of of novel family of hypothetical nucleolar proteins.


Pssm-ID: 462386  Cd Length: 202  Bit Score: 300.59  E-value: 4.03e-94
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223278379   471 MFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQA 550
Cdd:pfam08161    1 IAKALESLLSYKYQHAWKEVLNVLSALFEKLGKRSNPLLLPILKTLGDLRTSESFEFKKEADEVIGAAIRAMGPEVVLSI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223278379   551 VPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFC 630
Cdd:pfam08161   81 LPLNLDGPAGDIQPGRAWLLPLLRDNIRNTSLSFFKSEFLPLAEALFQKAKELEEAGKSVEAKIFETLVDQIWSLLPGFC 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 223278379   631 TRPTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITK 671
Cdd:pfam08161  161 NLPTDLKESFKSFAKLLGNLLYEQPELRPTICQALRTLVES 201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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