NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1869903519|ref|NP_055654|]
View 

phospholipid phosphatase-related protein type 4 isoform 1 [Homo sapiens]

Protein Classification

PAP2 phosphatase family protein( domain architecture ID 10130187)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to phospholipid phosphatase that catalyzes the conversion of phosphatidic acid to diacylglycerol

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 126-275 1.73e-68

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


:

Pssm-ID: 239479  Cd Length: 150  Bit Score: 221.35  E-value: 1.73e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 126 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKEnSYIVEDICSGSDLTVINSGRKSFPSQHA 205
Cdd:cd03384     1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDH-QYIADCTCCTGDPDLIREARLSFPSGHA 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869903519 206 TLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 275
Cdd:cd03384    80 SLSMYAAVFLALYLQARLKLrGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
 
Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 126-275 1.73e-68

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 221.35  E-value: 1.73e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 126 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKEnSYIVEDICSGSDLTVINSGRKSFPSQHA 205
Cdd:cd03384     1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDH-QYIADCTCCTGDPDLIREARLSFPSGHA 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869903519 206 TLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 275
Cdd:cd03384    80 SLSMYAAVFLALYLQARLKLrGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 135-274 4.22e-14

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 69.37  E-value: 4.22e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 135 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTslnvsckensyivedicsgsDLTVINSGRKSFPSQHATLAAFAAVY 214
Cdd:pfam01569   3 LLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVP--------------------APSTLPGLGYSFPSGHSATAFALALL 62

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 215 VSMYFNSTLtdssKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:pfam01569  63 LALLLRRLR----KIVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLV 118
acidPPc smart00014
Acid phosphatase homologues;
135-274 3.64e-13

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 66.60  E-value: 3.64e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519  135 VFGLCSTALITDIIQLSTGYQAPYFLtvckpnytslnvsckensyIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVY 214
Cdd:smart00014   1 ALLAVVSQLFNGVIKNYFGRPRPFFL-------------------SIGDACCTPNFLLTLEAGYSFPSGHTAFAFAFALF 61

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519  215 VSMYFNSTLTdsskllKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:smart00014  62 LLLYLPARAG------RKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVL 115
PLN02715 PLN02715
lipid phosphate phosphatase
 135-318 1.01e-08

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 57.37  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 135 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSckensyIVEDICSGSDLTViNSGRKSFPSQHATLAAFAAVY 214
Cdd:PLN02715  129 LFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKELYDA------LGGVICHGKAAEV-KEGHKSFPSGHTSWSFAGLTF 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 215 VSMYFNSTL---TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL--------------GLY 277
Cdd:PLN02715  202 LSLYLSGKIkafNGEGHVAKLCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCyrqfypnpyheegwGPY 281

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1869903519 278 AVgnFLPSDE-----SMFQHRDALRSLTdLNQDPNRLLSAKNGSSS 318
Cdd:PLN02715  282 AY--FKAAQErgvpvASSQNGDALRAMS-LQMDSTSLENMESGTST 324
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 199-274 1.12e-04

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 43.88  E-value: 1.12e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869903519 199 SFPSQHATLAAFAAVYVSMYFNSTLtdsskLLKPLLVFTFIIcgiicGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:COG0671   118 SFPSGHAAAAFALALVLALLLPRRW-----LAALLLALALLV-----GLSRVYLGVHYPSDVLAGALLGLAIALLL 183
 
Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 126-275 1.73e-68

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 221.35  E-value: 1.73e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 126 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKEnSYIVEDICSGSDLTVINSGRKSFPSQHA 205
Cdd:cd03384     1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDH-QYIADCTCCTGDPDLIREARLSFPSGHA 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869903519 206 TLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 275
Cdd:cd03384    80 SLSMYAAVFLALYLQARLKLrGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 59-273 3.84e-23

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 97.29  E-value: 3.84e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519  59 SLSMPYIEptQEAIPFLMLLSLAFAGPAITImvgegILYCCLSKRRNGVGlepninaggcnFNSFLrravrfvgVHVFGL 138
Cdd:cd03390     2 SISYPFAE--SETVPTWLLVIISVGIPLLVI-----ILISLFFRRSLWDL-----------HTSLL--------GLLLSV 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 139 CSTALITDIIQLSTGYQAPYFLTVCKPNYTSlnvscKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMY 218
Cdd:cd03390    56 SLNGVITNVLKNYAGRPRPDFLARCFPDGGT-----PSDTLVGIDICCTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLY 130

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1869903519 219 FNSTLT---DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALY 273
Cdd:cd03390   131 LAGKLHifdPRGSSWRLLLALLPLLLAILVAVSRTRDYRHHFSDVIAGSLIGLIIAYL 188
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 127-274 1.27e-18

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 82.12  E-value: 1.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 127 AVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYtslnvsckensyivedicsgsDLTVINSGRKSFPSQHAT 206
Cdd:cd01610     1 RRLLALLLLLALLAGLLLTGVLKYLFGRPRPYFLLRCGPDG---------------------DPLLLTEGGYSFPSGHAA 59

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869903519 207 LAAFAAVYVSMYFNStltdssKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:cd01610    60 FAFALALFLALLLPR------RLLRLLLGLLLLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALLV 121
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 135-274 4.22e-14

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 69.37  E-value: 4.22e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 135 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTslnvsckensyivedicsgsDLTVINSGRKSFPSQHATLAAFAAVY 214
Cdd:pfam01569   3 LLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVP--------------------APSTLPGLGYSFPSGHSATAFALALL 62

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 215 VSMYFNSTLtdssKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:pfam01569  63 LALLLRRLR----KIVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLV 118
acidPPc smart00014
Acid phosphatase homologues;
135-274 3.64e-13

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 66.60  E-value: 3.64e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519  135 VFGLCSTALITDIIQLSTGYQAPYFLtvckpnytslnvsckensyIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVY 214
Cdd:smart00014   1 ALLAVVSQLFNGVIKNYFGRPRPFFL-------------------SIGDACCTPNFLLTLEAGYSFPSGHTAFAFAFALF 61

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519  215 VSMYFNSTLTdsskllKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:smart00014  62 LLLYLPARAG------RKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVL 115
PLN02715 PLN02715
lipid phosphate phosphatase
 135-318 1.01e-08

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 57.37  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 135 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSckensyIVEDICSGSDLTViNSGRKSFPSQHATLAAFAAVY 214
Cdd:PLN02715  129 LFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKELYDA------LGGVICHGKAAEV-KEGHKSFPSGHTSWSFAGLTF 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 215 VSMYFNSTL---TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL--------------GLY 277
Cdd:PLN02715  202 LSLYLSGKIkafNGEGHVAKLCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCyrqfypnpyheegwGPY 281

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1869903519 278 AVgnFLPSDE-----SMFQHRDALRSLTdLNQDPNRLLSAKNGSSS 318
Cdd:PLN02715  282 AY--FKAAQErgvpvASSQNGDALRAMS-LQMDSTSLENMESGTST 324
PLN02731 PLN02731
Putative lipid phosphate phosphatase
 120-267 4.44e-08

Putative lipid phosphate phosphatase


Pssm-ID: 178332  Cd Length: 333  Bit Score: 55.42  E-value: 4.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 120 FNSFLRRAVRFVGVHVFGLC----STALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSckensyIVEDICSGsDLTVINS 195
Cdd:PLN02731  104 FIYFRRRDVYDLHHAVLGLLysvlVTAVLTDAIKNAVGRPRPDFFWRCFPDGKALYDS------LGDVICHG-DKSVIRE 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869903519 196 GRKSFPSQHATLAAFAAVYVSMYFNSTLT---DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIG 267
Cdd:PLN02731  177 GHKSFPSGHTSWSFSGLGFLSLYLSGKIQafdGKGHVAKLCIVILPLLFAALVGISRVDDYWHHWQDVFAGGLLG 251
PLN02250 PLN02250
lipid phosphate phosphatase
 135-273 5.41e-08

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 55.32  E-value: 5.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 135 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSyivedICSGsDLTVINSGRKSFPSQHATLAAFAAVY 214
Cdd:PLN02250  104 LFSVLITGVITDAIKDAVGRPRPDFFWRCFPDGKGVFHPVTTDV-----LCTG-AKSVIKEGHKSFPSGHTSWSFAGLGF 177

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869903519 215 VSMYFNSTL---TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALY 273
Cdd:PLN02250  178 LSLYLSGKIrvfDRRGHVAKLCIVFLPLLVAALVGVSRVDDYWHHWQDVFAGALIGLTVASF 239
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 199-277 1.40e-05

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 46.16  E-value: 1.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 199 SFPSQHAT--LAAFAAVYvsmyfnstltdsskLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGL 276
Cdd:cd03389   119 SFPSGHSAtaGAAAAALA--------------LLFPRYRWAFILLALLIAFSRVIVGAHYPSDVIAGSLLGAVTALALYQ 184


                  .
gi 1869903519 277 Y 277
Cdd:cd03389   185 R 185
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 199-267 1.06e-04

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 43.08  E-value: 1.06e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869903519 199 SFPSQHATLAAFaaVYVSMYFNSTLTDSskLLKPLLVFTFIIcgiicGLTRITQYKNHPVDVYCGFLIG 267
Cdd:cd03391    92 SFPSGHASRAAF--VARFLLNHLVLAVP--LRVLLVLWATVV-----GISRVLLGRHHVLDVLAGAFLG 151
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 199-274 1.12e-04

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 43.88  E-value: 1.12e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869903519 199 SFPSQHATLAAFAAVYVSMYFNSTLtdsskLLKPLLVFTFIIcgiicGLTRITQYKNHPVDVYCGFLIGGGIALYL 274
Cdd:COG0671   118 SFPSGHAAAAFALALVLALLLPRRW-----LAALLLALALLV-----GLSRVYLGVHYPSDVLAGALLGLAIALLL 183
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 189-276 5.14e-04

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 41.48  E-value: 5.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869903519 189 DLTVINSGRK-SFPSQHATLAAFAAVYVSMYFNStltdsskllKPLLVFTFIICgIICGLTRITQYKNHPVDVYCGFLIG 267
Cdd:cd03395    94 LVVLGDQGGSySFASSHAANSFALALFIWLFFRR---------GLFSPVLLLWA-LLVGYSRVYVGVHYPGDVIAGALIG 163


                  ....*....
gi 1869903519 268 GGIALYLGL 276
Cdd:cd03395   164 IISGLLFYL 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH