|
Name |
Accession |
Description |
Interval |
E-value |
| PEP_TPR_lipo |
TIGR02917 |
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ... |
110-781 |
6.46e-25 |
|
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.
Pssm-ID: 274350 [Multi-domain] Cd Length: 899 Bit Score: 112.48 E-value: 6.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 110 ITQATLLYTMADKIIMYDQNHLLGRACFcLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKA 189
Cdd:TIGR02917 209 IELALAAYRKAIALRPNNIAVLLALATI-LIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDA 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 190 LRTNPGCPAEVRLGmGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNgvqLLSRAYTIDPSNP 269
Cdd:TIGR02917 288 LKSAPEYLPALLLA-GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIA---TLSPALGLDPDDP 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 270 MVLNHLANHFFFKKDYSK-VQHLAlhafHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFAS----SSFVLPF 344
Cdd:TIGR02917 364 AALSLLGEAYLALGDFEKaAEYLA----KATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPelgrADLLLIL 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 345 FGL-----------------------------GQMYIYRGDKENASQCFEKVLKAYPNNYetmKILGSLYAASEDQEKRD 395
Cdd:TIGR02917 440 SYLrsgqfdkalaaakklekkqpdnaslhnllGAIYLGKGDLAKAREAFEKALSIEPDFF---PAAANLARIDIQEGNPD 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 396 IAKGHLKKVTEQYPDDVEA-------------------WIELAQILEQTDIQGA--LSAY-------GTATRILQEKVQ- 446
Cdd:TIGR02917 517 DAIQRFEKVLTIDPKNLRAilalaglylrtgneeeavaWLEKAAELNPQEIEPAlaLAQYylgkgqlKKALAILNEAADa 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 447 ADVPPEILNNVGALHFRLGNLGEAKKYF--LASLDRAKAEAEhdehyynaisvttsYNLARLYEAMCEFHEAEKLYKNIL 524
Cdd:TIGR02917 597 APDSPEAWLMLGRAQLAAGDLNKAVSSFkkLLALQPDSALAL--------------LLLADAYAVMKNYAKAITSLKRAL 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 525 REHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILK-QPSTQSDTYs 603
Cdd:TIGR02917 663 ELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKrAPSSQNAIK- 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 604 mlaLGNVWLQTLHQPtrdrekekrhqdRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDV 683
Cdd:TIGR02917 742 ---LHRALLASGNTA------------EAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVV 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 684 WLNLAHIYVEQKQyISAVQMYENCLRKfyKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLqr 763
Cdd:TIGR02917 807 LNNLAWLYLELKD-PRALEYAERALKL--APNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALAL-- 881
|
730
....*....|....*...
gi 7661950 764 LATSVLKDEKSNLKEVLN 781
Cdd:TIGR02917 882 LATGRKAEARKELDKLLN 899
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
340-710 |
3.02e-23 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 100.96 E-value: 3.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 340 FVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELA 419
Cdd:COG2956 7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR---AIRIHQKLLERDPDRAEALLELA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 420 QIleqtdiqgalsaygtatrilqekvqadvppeilnnvgalHFRLGNLGEAKKYFLASLDRakaeaehDEHYYNAIsvtt 499
Cdd:COG2956 84 QD---------------------------------------YLKAGLLDRAEELLEKLLEL-------DPDDAEAL---- 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 500 sYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQ 579
Cdd:COG2956 114 -RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 580 EWgpgqkkferilkqpstqsdtysmlalgnvwlqtlhqptrdrekekrhqDRALAIYKQVLRNDAKNLYAANGIGAVLAH 659
Cdd:COG2956 193 DY------------------------------------------------EEAIAALERALEQDPDYLPALPRLAELYEK 224
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 7661950 660 KGYFREARDVFAQVREATADiSDVWLNLAHIYVEQKQYISAVQMYENCLRK 710
Cdd:COG2956 225 LGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRR 274
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.73e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 71.86 E-value: 1.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSDNESVQ 1108
Cdd:NF033609 704 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDS 782
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 1109 SGRSHSGvSENDSRPASPSaESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 783 DSDSDSD-SDSDSDSDSDS-DSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 845
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
2.36e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 71.48 E-value: 2.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
Cdd:NF033609 706 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 785
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1109 SGRSHSGVSENDSRPASPS-AESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGSEHGSD---DSD 1173
Cdd:NF033609 786 SDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsdsDSD 855
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
4.46e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 70.71 E-value: 4.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ---SDNE 1105
Cdd:NF033609 694 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdSDSD 773
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1106 SVQSGRSHSGvSENDSRPASPSaESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 774 SDSDSDSDSD-SDSDSDSDSDS-DSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 841
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
5.10e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 70.32 E-value: 5.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSD 1103
Cdd:NF033609 627 DSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SD 705
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 1104 NESVQSGRSHSGvSENDSRPASPS-AESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 706 SDSDSDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 777
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
1.19e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 69.17 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-S 1102
Cdd:NF033609 683 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdS 762
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 1103 DNESVQSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 763 DSDSDSDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 833
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.57e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.78 E-value: 1.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
Cdd:NF033609 608 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 687
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 1109 SGRSHSGVSENDSRPASPSaESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 688 SDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 751
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.80e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.78 E-value: 1.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSDNESVQ 1108
Cdd:NF033609 638 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDS 716
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1109 SGRSHSGvSENDSRPASPS-AESDHESERGSDNEG---SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 717 DSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSDSdsdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 785
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.83e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.78 E-value: 1.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
Cdd:NF033609 676 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 755
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7661950 1109 SGRSHSGVSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 756 SDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 821
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
2.26e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.40 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-SDNESV 1107
Cdd:NF033609 620 SDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSD 699
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 700 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 765
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
3.04e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.01 E-value: 3.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-S 1102
Cdd:NF033609 653 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdS 732
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 1103 DNESVQSGRSHSGvSENDSRPASPS-AESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 733 DSDSDSDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 805
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
3.34e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.01 E-value: 3.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSD 1103
Cdd:NF033609 675 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 754
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 1104 NESVQSGRSHSGVSENDSRPASPS---AESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 755 DSDSDSDSDSDSDSDSDSDSDSDSdsdSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 829
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
3.51e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 67.63 E-value: 3.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-SDNESV 1107
Cdd:NF033609 720 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSD 799
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 800 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSESDSNsDSE 865
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
3.73e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 67.63 E-value: 3.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSD 1103
Cdd:NF033609 645 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SD 723
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 1104 NESVQSGRSHSGV-SENDSRPASPS-AESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 724 SDSDSDSDSDSDSdSDSDSDSDSDSdSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 797
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
3.96e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 67.63 E-value: 3.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-SDNESV 1107
Cdd:NF033609 588 SDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSdSDSDSD 667
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 668 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 733
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
5.90e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 66.86 E-value: 5.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSE-QSDNESV 1107
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 791
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 792 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSE 857
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1165 |
1.00e-10 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 66.47 E-value: 1.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSDNESVQ 1108
Cdd:NF033609 732 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDS 810
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1109 SGRSHSGVSENDSRPASPSAESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGS 1165
Cdd:NF033609 811 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSESDSNSDSESGS 868
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.53e-10 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 65.70 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSE---QSDNE 1105
Cdd:NF033609 580 SDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDsdsDSDSD 659
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7661950 1106 SVQSGRSHSGV-SENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 660 SDSDSDSDSDSdSDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 729
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1172 |
5.90e-10 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 63.77 E-value: 5.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ---SDNE 1105
Cdd:NF033609 750 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdSDSD 829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1106 SVQSGRSHSGvSENDSRPASPSA-ESDHESERGSDNEG-------------SGQGSGNESEPEGSNNEASDRGSEHGSDD 1171
Cdd:NF033609 830 SDSDSDSDSD-SDSDSDSDSDSDsDSDSESDSNSDSESgsnnnvvppnspkNGTNASNKNEAKDSKEPLPDTGSEDEANT 908
|
.
gi 7661950 1172 S 1172
Cdd:NF033609 909 S 909
|
|
| TPR_12 |
pfam13424 |
Tetratricopeptide repeat; |
453-521 |
2.21e-06 |
|
Tetratricopeptide repeat;
Pssm-ID: 315987 [Multi-domain] Cd Length: 77 Bit Score: 46.61 E-value: 2.21e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7661950 453 ILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDehyyNAISVTTSYNLARLYEAMCEFHEAEKLYK 521
Cdd:pfam13424 5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPD----HPLTATTLLNLGRLYLELGRYEEALELLE 69
|
|
| DMP1 |
pfam07263 |
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix ... |
1040-1166 |
9.43e-06 |
|
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth specific protein initially identified from mineralized dentin. DMP1 is primarily localized in the nuclear compartment of undifferentiated osteoblasts. In the nucleus, DMP1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the early phase of osteoblast maturation, Ca(2+) surges into the nucleus from the cytoplasm, triggering the phosphorylation of DMP1 by a nuclear isoform of casein kinase II. This phosphorylated DMP1 is then exported out into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP1 is a unique molecule that initiates osteoblast differentiation by transcription in the nucleus and orchestrates mineralized matrix formation extracellularly, at later stages of osteoblast maturation. The DMP1 gene has been found to be ectopically expressed in lung cancer although the reason for this is unknown.
Pssm-ID: 462128 [Multi-domain] Cd Length: 519 Bit Score: 49.54 E-value: 9.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1040 NSDSDEDEQRKKCASSESDSDENQnksgseagsprrprrqrsdQDSDSDQPSRKRRPSG-SEQSDNESVQSGR-SHSGVS 1117
Cdd:pfam07263 379 DSDSSEEDSLSTFSSSESESREEQ-------------------ADSESNESLRSSEESPeSSEDENSSSQEGLqSHSAST 439
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 7661950 1118 ENDSRPASPSAESDHESERGSDNEGSGQGSgnesepEGSNNEASDRGSE 1166
Cdd:pfam07263 440 ESQSEESQSEQDSQSEEDDESDSQDSSRSK------EDSNSTESTSSSE 482
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
1029-1168 |
1.54e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 45.73 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHpRNSNSNSDSDEDEQRkkcASSESDSDENQNKSGSEAGsprrprrqrsdqDSDSDQPSRKRRPSGS----EQSDN 1104
Cdd:PHA03169 62 AEQGH-RQTESDTETAEESRH---GEKEERGQGGPSGSGSESV------------GSPTPSPSGSAEELASglspENTSG 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1105 ESVQSGRSHSGVSENDSRP--ASPSAESDHESERGSDNEGSGQGSGNES--EPEGSNNEASDRGSEHG 1168
Cdd:PHA03169 126 SSPESPASHSPPPSPPSHPgpHEPAPPESHNPSPNQQPSSFLQPSHEDSpeEPEPPTSEPEPDSPGPP 193
|
|
| dermokine |
cd21118 |
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
1032-1169 |
2.33e-03 |
|
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.
Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 41.91 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1032 GHPRNSNSNSD------SDEDEqrkkcASSESDSDENqnkSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNe 1105
Cdd:cd21118 191 GTVRGNNQNSGctnpppSGSHE-----SFSNSGGSSS---SGSSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSGN- 261
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 1106 svqSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEgSNNEASDRGSEHGS 1169
Cdd:cd21118 262 ---SGGSNGGSSGNSGSGSGGSSSGGSNGWGGSSSSGGSGGSGGGNKPE-CNNPGNDVRMAGGG 321
|
|
| ACL4-like |
cd24142 |
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ... |
349-447 |
4.92e-03 |
|
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.
Pssm-ID: 467942 [Multi-domain] Cd Length: 306 Bit Score: 40.30 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 349 QMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDD-VEAWIELAQILEQTDi 427
Cdd:cd24142 8 EELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEE---AREVLLRAIELDPDGgYEKYLYLGQLSGGEE- 83
|
90 100
....*....|....*....|
gi 7661950 428 qgALSAYGTATRILQEKVQA 447
Cdd:cd24142 84 --ALQYYEKGIEILEEELQA 101
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PEP_TPR_lipo |
TIGR02917 |
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ... |
110-781 |
6.46e-25 |
|
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.
Pssm-ID: 274350 [Multi-domain] Cd Length: 899 Bit Score: 112.48 E-value: 6.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 110 ITQATLLYTMADKIIMYDQNHLLGRACFcLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKA 189
Cdd:TIGR02917 209 IELALAAYRKAIALRPNNIAVLLALATI-LIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDA 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 190 LRTNPGCPAEVRLGmGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNgvqLLSRAYTIDPSNP 269
Cdd:TIGR02917 288 LKSAPEYLPALLLA-GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIA---TLSPALGLDPDDP 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 270 MVLNHLANHFFFKKDYSK-VQHLAlhafHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFAS----SSFVLPF 344
Cdd:TIGR02917 364 AALSLLGEAYLALGDFEKaAEYLA----KATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPelgrADLLLIL 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 345 FGL-----------------------------GQMYIYRGDKENASQCFEKVLKAYPNNYetmKILGSLYAASEDQEKRD 395
Cdd:TIGR02917 440 SYLrsgqfdkalaaakklekkqpdnaslhnllGAIYLGKGDLAKAREAFEKALSIEPDFF---PAAANLARIDIQEGNPD 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 396 IAKGHLKKVTEQYPDDVEA-------------------WIELAQILEQTDIQGA--LSAY-------GTATRILQEKVQ- 446
Cdd:TIGR02917 517 DAIQRFEKVLTIDPKNLRAilalaglylrtgneeeavaWLEKAAELNPQEIEPAlaLAQYylgkgqlKKALAILNEAADa 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 447 ADVPPEILNNVGALHFRLGNLGEAKKYF--LASLDRAKAEAEhdehyynaisvttsYNLARLYEAMCEFHEAEKLYKNIL 524
Cdd:TIGR02917 597 APDSPEAWLMLGRAQLAAGDLNKAVSSFkkLLALQPDSALAL--------------LLLADAYAVMKNYAKAITSLKRAL 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 525 REHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILK-QPSTQSDTYs 603
Cdd:TIGR02917 663 ELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKrAPSSQNAIK- 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 604 mlaLGNVWLQTLHQPtrdrekekrhqdRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDV 683
Cdd:TIGR02917 742 ---LHRALLASGNTA------------EAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVV 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 684 WLNLAHIYVEQKQyISAVQMYENCLRKfyKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLqr 763
Cdd:TIGR02917 807 LNNLAWLYLELKD-PRALEYAERALKL--APNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALAL-- 881
|
730
....*....|....*...
gi 7661950 764 LATSVLKDEKSNLKEVLN 781
Cdd:TIGR02917 882 LATGRKAEARKELDKLLN 899
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
340-710 |
3.02e-23 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 100.96 E-value: 3.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 340 FVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELA 419
Cdd:COG2956 7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR---AIRIHQKLLERDPDRAEALLELA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 420 QIleqtdiqgalsaygtatrilqekvqadvppeilnnvgalHFRLGNLGEAKKYFLASLDRakaeaehDEHYYNAIsvtt 499
Cdd:COG2956 84 QD---------------------------------------YLKAGLLDRAEELLEKLLEL-------DPDDAEAL---- 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 500 sYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQ 579
Cdd:COG2956 114 -RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 580 EWgpgqkkferilkqpstqsdtysmlalgnvwlqtlhqptrdrekekrhqDRALAIYKQVLRNDAKNLYAANGIGAVLAH 659
Cdd:COG2956 193 DY------------------------------------------------EEAIAALERALEQDPDYLPALPRLAELYEK 224
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 7661950 660 KGYFREARDVFAQVREATADiSDVWLNLAHIYVEQKQYISAVQMYENCLRK 710
Cdd:COG2956 225 LGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRR 274
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
205-480 |
1.11e-22 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 99.42 E-value: 1.11e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 205 GHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSiknGVQLLSRAYTIDPSNPMVLNHLANHFFFKKD 284
Cdd:COG2956 15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR---AIRIHQKLLERDPDRAEALLELAQDYLKAGL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 285 YSKVQHLALHAFhntEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLpFFGLGQMYIYRGDKENASQCF 364
Cdd:COG2956 92 LDRAEELLEKLL---ELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHA-YCELAELYLEQGDYDEAIEAL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 365 EKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQtdiqgaLSAYGTATRILQEK 444
Cdd:COG2956 168 EKALKLDPDCARALLLLAELYLEQGDYEE---AIAALERALEQDPDYLPALPRLAELYEK------LGDPEEALELLRKA 238
|
250 260 270
....*....|....*....|....*....|....*.
gi 7661950 445 VQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR 480
Cdd:COG2956 239 LELDPSDDLLLALADLLERKEGLEAALALLERQLRR 274
|
|
| PEP_TPR_lipo |
TIGR02917 |
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ... |
156-761 |
4.99e-21 |
|
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.
Pssm-ID: 274350 [Multi-domain] Cd Length: 899 Bit Score: 99.77 E-value: 4.99e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 156 LNQSPNNIPALLGKACISFNKkdYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGAL 235
Cdd:TIGR02917 85 LGYPKNQVLPLLARAYLLQGK--FQQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 236 VGLAVLELNNKEadsIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKV-----QHLALHAFHNT----------- 299
Cdd:TIGR02917 163 LGLAQLALAENR---FDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELAlaayrKAIALRPNNIAvllalatilie 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 300 ----EVEAMQAESCYQLARSfHVQEDYDQAfQYYYQATQFASS------------SFVLPFFGLGQMYIYRGDKENASQC 363
Cdd:TIGR02917 240 agefEEAEKHADALLKKAPN-SPLAHYLKA-LVDFQKKNYEDAretlqdalksapEYLPALLLAGASEYQLGNLEQAYQY 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 364 FEKVLKAYPNNYETMKILGSLYAASEDQ-----------------------------EKRDIAKGH--LKKVTEQYPDDV 412
Cdd:TIGR02917 318 LNQILKYAPNSHQARRLLASIQLRLGRVdeaiatlspalgldpddpaalsllgeaylALGDFEKAAeyLAKATELDPENA 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 413 EAWIELAQI-LEQTDIQGALSAYGTATRILQEKVQADV----------------------------PPEILNNVGALHFR 463
Cdd:TIGR02917 398 AARTQLGISkLSQGDPSEAIADLETAAQLDPELGRADLllilsylrsgqfdkalaaakklekkqpdNASLHNLLGAIYLG 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 464 LGNLGEAKKYFLASLdrakaeaEHDEHYYNAISvttsyNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARD 543
Cdd:TIGR02917 478 KGDLAKAREAFEKAL-------SIEPDFFPAAA-----NLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLR 545
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 544 KGNFYEASDWFKEALQIN----------------------------------QDHPDAWSLIGNLHLAKQEWGPGQKKFE 589
Cdd:TIGR02917 546 TGNEEEAVAWLEKAAELNpqeiepalalaqyylgkgqlkkalailneaadaaPDSPEAWLMLGRAQLAAGDLNKAVSSFK 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 590 RILKQPSTQSDTYSMLAlgnvwlqtlhqptrDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDV 669
Cdd:TIGR02917 626 KLLALQPDSALALLLLA--------------DAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKI 691
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 670 FAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNtevVLYLARALFKCGKLQECKQTLLKARHVAPS 749
Cdd:TIGR02917 692 AKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQN---AIKLHRALLASGNTAEAVKTLEAWLKTHPN 768
|
730
....*....|..
gi 7661950 750 DTVLMFNVALVL 761
Cdd:TIGR02917 769 DAVLRTALAELY 780
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
232-527 |
1.53e-18 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 87.09 E-value: 1.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 232 VGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKvqhlALHAFHNT-EVEAMQAESCY 310
Cdd:COG2956 5 VAAALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR----AIRIHQKLlERDPDRAEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 311 QLARSFHVQEDYDQAFQYYYQATQFASSSfVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASED 390
Cdd:COG2956 81 ELAQDYLKAGLLDRAEELLEKLLELDPDD-AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 391 QEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQT-DIQGALSAYgtaTRILQekvQADVPPEILNNVGALHFRLGNLGE 469
Cdd:COG2956 160 YDE---AIEALEKALKLDPDCARALLLLAELYLEQgDYEEAIAAL---ERALE---QDPDYLPALPRLAELYEKLGDPEE 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 470 AKKYFLASLDRAKAEAEHdehyynaisvttsYNLARLYEAMCEFHEAEKLYKNILREH 527
Cdd:COG2956 231 ALELLRKALELDPSDDLL-------------LALADLLERKEGLEAALALLERQLRRH 275
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
139-444 |
5.88e-18 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 85.55 E-value: 5.88e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 139 LLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGcPAEVRLGMGHCFVKLNKLEKAR 218
Cdd:COG2956 18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD-RAEALLELAQDYLKAGLLDRAE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 219 LAFSRALELNSKCVGALVGLAVLELNNKEADsikNGVQLLSRAYTIDPSNpmvlnhlanhfffkkdyskvqhlalhafhn 298
Cdd:COG2956 97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWE---KAIEVLERLLKLGPEN------------------------------ 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 299 teveamqAESCYQLARSFHVQEDYDQAFQYYYQATQfASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETM 378
Cdd:COG2956 144 -------AHAYCELAELYLEQGDYDEAIEALEKALK-LDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 379 KILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDvEAWIELAQILEQTdiQGALSAYGTATRILQEK 444
Cdd:COG2956 216 PRLAELYEKLGDPEE---ALELLRKALELDPSD-DLLLALADLLERK--EGLEAALALLERQLRRH 275
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
406-666 |
3.37e-16 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 79.67 E-value: 3.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 406 EQYPDDVEAWIELAQILEQT-DIQGALSAYGTATRILQEKVQAdvppeiLNNVGALHFRLGNLGEAKKYFLASLdrakae 484
Cdd:COG0457 2 ELDPDDAEAYNNLGLAYRRLgRYEEAIEDYEKALELDPDDAEA------LYNLGLAYLRLGRYEEALADYEQAL------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 485 aEHDEHYYNAIsvttsYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDH 564
Cdd:COG0457 70 -ELDPDDAEAL-----NNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDD 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 565 PDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDA 644
Cdd:COG0457 144 ADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELL 223
|
250 260
....*....|....*....|..
gi 7661950 645 KNLYAANGIGAVLAHKGYFREA 666
Cdd:COG0457 224 LLALALLLALRLAALALYQYRA 245
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
524-744 |
5.30e-16 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 78.90 E-value: 5.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 524 LREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYS 603
Cdd:COG0457 1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 604 MLALgnvWLQTLHQPtrdrekekrhqDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDV 683
Cdd:COG0457 81 NLGL---ALQALGRY-----------EEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7661950 684 WLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCGKLQECKQTLLKAR 744
Cdd:COG0457 147 LYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
160-336 |
3.77e-15 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 76.58 E-value: 3.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 160 PNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCpAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLA 239
Cdd:COG0457 5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDD-AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 240 VLELNNKEADSiknGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKvqhlALHAFHNT-EVEAMQAESCYQLARSFHV 318
Cdd:COG0457 84 LALQALGRYEE---ALEDYDKALELDPDDAEALYNLGLALLELGRYDE----AIEAYERAlELDPDDADALYNLGIALEK 156
|
170
....*....|....*...
gi 7661950 319 QEDYDQAFQYYYQATQFA 336
Cdd:COG0457 157 LGRYEEALELLEKLEAAA 174
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
450-724 |
5.01e-15 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 80.04 E-value: 5.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 450 PPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPN 529
Cdd:COG3914 31 ELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPD 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 530 YVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLhlakqewgpgqkkferilkqpstqsdtysmlalgn 609
Cdd:COG3914 111 NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEA----------------------------------- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 610 vwLQTLHQPtrdrekekrhqDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAH 689
Cdd:COG3914 156 --LRRLGRL-----------EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLF 222
|
250 260 270
....*....|....*....|....*....|....*
gi 7661950 690 IYVEQKQyISAVQMYENCLRKFYKHQNTEVVLYLA 724
Cdd:COG3914 223 ALRQACD-WEVYDRFEELLAALARGPSELSPFALL 256
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
451-700 |
6.03e-15 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 75.81 E-value: 6.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 451 PEILNNVGALHFRLGNLGEAKKYFLASLdrakaeaEHDEHYYNAIsvttsYNLARLYEAMCEFHEAEKLYKNILREHPNY 530
Cdd:COG0457 8 AEAYNNLGLAYRRLGRYEEAIEDYEKAL-------ELDPDDAEAL-----YNLGLAYLRLGRYEEALADYEQALELDPDD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 531 VDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSMLALgnv 610
Cdd:COG0457 76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGI--- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 611 wlqTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHI 690
Cdd:COG0457 153 ---ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
|
250
....*....|
gi 7661950 691 YVEQKQYISA 700
Cdd:COG0457 230 LLALRLAALA 239
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
380-605 |
2.94e-14 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 77.34 E-value: 2.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 380 ILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEIlnnvgA 459
Cdd:COG3914 12 LAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA-----L 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 460 LHFRLGNLGEAkkyfLASLDRAkaeAEHDEHYYNAIsvttsYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGA 539
Cdd:COG3914 87 LLQALGRYEEA----LALYRRA---LALNPDNAEAL-----FNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 540 MARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSML 605
Cdd:COG3914 155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
|
|
| PEP_TPR_lipo |
TIGR02917 |
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ... |
175-886 |
3.08e-14 |
|
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.
Pssm-ID: 274350 [Multi-domain] Cd Length: 899 Bit Score: 77.82 E-value: 3.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 175 NKKDYRGALAYYKKALRTNPGcPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSIkng 254
Cdd:TIGR02917 34 QKNKYKAAIIQLKNALQKDPN-DAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQV--- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 255 VQLLSRAYTID-PSNPMVLNHLANHFFFKKDYSKVQHLALHAFhntEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQAT 333
Cdd:TIGR02917 110 LDELPGKTLLDdEGAAELLALRGLAYLGLGQLELAQKSYEQAL---AIDPRSLYAKLGLAQLALAENRFDEARALIDEVL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 334 QfASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGS-LYAASEDQEkrdiAKGHLKKVTEQYPDDV 412
Cdd:TIGR02917 187 T-ADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATiLIEAGEFEE----AEKHADALLKKAPNSP 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 413 EAWIELAQI-LEQTDIQGALSAygtatriLQEKVQADvpPEILNNV---GALHFRLGNLGEAKKYFLASLDRAKaeaehD 488
Cdd:TIGR02917 262 LAHYLKALVdFQKKNYEDARET-------LQDALKSA--PEYLPALllaGASEYQLGNLEQAYQYLNQILKYAP-----N 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 489 EHYYNAISVTTSYNLARLYEAMCEFHEAEKLyknilrehpNYVDCYLR--LGAMARDKGNFYEASDWFKEALQINQDHPD 566
Cdd:TIGR02917 328 SHQARRLLASIQLRLGRVDEAIATLSPALGL---------DPDDPAALslLGEAYLALGDFEKAAEYLAKATELDPENAA 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 567 AWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSMLALGNVwlqtlhqptrdrekeKRHQ-DRALAIYKQVLRNDAK 645
Cdd:TIGR02917 399 ARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYL---------------RSGQfDKALAAAKKLEKKQPD 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 646 NLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHqnTEVVLYLAR 725
Cdd:TIGR02917 464 NASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKN--LRAILALAG 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 726 ALFKCGKLQECKQTLLKARHVAPSDTVLmfnvalvlqRLATSVLKDEKSNLKEVLNAVKELELAHR-YFSYLSKVGD--K 802
Cdd:TIGR02917 542 LYLRTGNEEEAVAWLEKAAELNPQEIEP---------ALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRaqL 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 803 MRFDLALAATEARQCSDLLSQ---AQYHVA----RARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLl 875
Cdd:TIGR02917 613 AAGDLNKAVSSFKKLLALQPDsalALLLLAdayaVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKI- 691
|
730
....*....|.
gi 7661950 876 eqrAQYVEKTK 886
Cdd:TIGR02917 692 ---AKSLQKQH 699
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
303-443 |
6.16e-14 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 70.22 E-value: 6.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 303 AMQAESCYQLARSFHVQEDYDQAFQYYYQATQfASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILG 382
Cdd:COG4783 1 AACAEALYALAQALLLAGDYDEAEALLEKALE-LDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 7661950 383 SLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQT-DIQGALSAYGTATRILQE 443
Cdd:COG4783 80 LALLKAGDYDE---ALALLEKALKLDPEHPEAYLRLARAYRALgRPDEAIAALEKALELDPD 138
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
345-579 |
3.07e-13 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 70.81 E-value: 3.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 345 FGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQ 424
Cdd:COG0457 12 NNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEE---ALADYEQALELDPDDAEALNNLGLALQA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 425 T-DIQGALSAYGTATRILQEKvqadvpPEILNNVGALHFRLGNLGEAKKYFLASLdrakaeaEHDEHYYNAIsvttsYNL 503
Cdd:COG0457 89 LgRYEEALEDYDKALELDPDD------AEALYNLGLALLELGRYDEAIEAYERAL-------ELDPDDADAL-----YNL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 504 ARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQ 579
Cdd:COG0457 151 GIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLA 226
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
137-332 |
4.59e-13 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 70.42 E-value: 4.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 137 FCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCpAEVRLGMGHCFVKLNKLEK 216
Cdd:COG0457 16 LAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-AEALNNLGLALQALGRYEE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 217 ARLAFSRALELNSKCVGALVGLAVLELNNKEADsikNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAF 296
Cdd:COG0457 95 ALEDYDKALELDPDDAEALYNLGLALLELGRYD---EAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLE 171
|
170 180 190
....*....|....*....|....*....|....*.
gi 7661950 297 HNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQA 332
Cdd:COG0457 172 AAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
630-857 |
1.19e-12 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 69.27 E-value: 1.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 630 DRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLR 709
Cdd:COG0457 25 EEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 710 kfYKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATsvLKDEKSNLKEVLNAVKELELA 789
Cdd:COG0457 105 --LDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGR--YEEALELLEKLEAAALAALLA 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 790 HRYFSYLSKVGDKMRFDLALAATEARQcsdLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLL 857
Cdd:COG0457 181 AALGEAALALAAAEVLLALLLALEQAL---RKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.73e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 71.86 E-value: 1.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSDNESVQ 1108
Cdd:NF033609 704 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDS 782
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 1109 SGRSHSGvSENDSRPASPSaESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 783 DSDSDSD-SDSDSDSDSDS-DSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 845
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
2.36e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 71.48 E-value: 2.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
Cdd:NF033609 706 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 785
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1109 SGRSHSGVSENDSRPASPS-AESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGSEHGSD---DSD 1173
Cdd:NF033609 786 SDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsdsDSD 855
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
289-514 |
2.85e-12 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 71.18 E-value: 2.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 289 QHLALHAFHNTEVEAMQAESC---YQLARSFHVQEDYDQAFQYYYQATQFASSSFVLpFFGLGQMYIYRGDKENASQCFE 365
Cdd:COG3914 58 ALLALAAGEAAAAAAALLLLAallELAALLLQALGRYEEALALYRRALALNPDNAEA-LFNLGNLLLALGRLEEALAALR 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 366 KVLKAYPNNYETMKILGSLYaasEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQT-DIQGALSAYGTATRILQEK 444
Cdd:COG3914 137 RALALNPDFAEAYLNLGEAL---RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLgRLEEAIAAYRRALELDPDN 213
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 445 VQAdvppeilnNVGALHFRLGNLG-EAKKYFLASLDRAKAEAEHDE----HYYNAISVTTSYNLARLYEAMCEFH 514
Cdd:COG3914 214 ADA--------HSNLLFALRQACDwEVYDRFEELLAALARGPSELSpfalLYLPDDDPAELLALARAWAQLVAAA 280
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
28-332 |
2.99e-12 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 68.60 E-value: 2.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 28 DEVISILKQEHTQLHIWIALALEYYKQGKTEEFVKLLEaaridgNLDYRDHEKDQMtcLDTLAAYYVQQARkeknkdnkk 107
Cdd:COG2956 29 DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQ------KLLERDPDRAEA--LLELAQDYLKAGL--------- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 108 dlitqatllytmadkiimydqnhllgracfcllegdkMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYK 187
Cdd:COG2956 92 -------------------------------------LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLE 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 188 KALRTNPGCpAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADsikNGVQLLSRAYTIDPS 267
Cdd:COG2956 135 RLLKLGPEN-AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYE---EAIAALERALEQDPD 210
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 268 NPMVLNHLANHFFFKKDYSKvqhlALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQA 332
Cdd:COG2956 211 YLPALPRLAELYEKLGDPEE----ALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQ 271
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
4.46e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 70.71 E-value: 4.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ---SDNE 1105
Cdd:NF033609 694 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdSDSD 773
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1106 SVQSGRSHSGvSENDSRPASPSaESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 774 SDSDSDSDSD-SDSDSDSDSDS-DSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 841
|
|
| PEP_TPR_lipo |
TIGR02917 |
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ... |
46-524 |
4.87e-12 |
|
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.
Pssm-ID: 274350 [Multi-domain] Cd Length: 899 Bit Score: 70.50 E-value: 4.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 46 ALALEYYKQGKTEEFVKLLEAAridgnldYRDHEKDQMTCLdTLAAYYVQQARkeknkdNKKDLITQATLLYTMADKIIM 125
Cdd:TIGR02917 538 ALAGLYLRTGNEEEAVAWLEKA-------AELNPQEIEPAL-ALAQYYLGKGQ------LKKALAILNEAADAAPDSPEA 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 126 YDqnhLLGRAcfcLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKkalrtnpgcpaevrlgmg 205
Cdd:TIGR02917 604 WL---MLGRA---QLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLK------------------ 659
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 206 hcfvklnklekarlafsRALELNSKCVGALVGLAVLELNNKEADSIKNGVQLLsraytidpsnpmvlnhlanhfffkkdy 285
Cdd:TIGR02917 660 -----------------RALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSL--------------------------- 695
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 286 sKVQHLALHAFHNteveamqaescyQLARSFHVQEDYDQAFQYYYQATQFASSSFVLpfFGLGQMYIYRGDKENASQCFE 365
Cdd:TIGR02917 696 -QKQHPKAALGFE------------LEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA--IKLHRALLASGNTAEAVKTLE 760
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 366 KVLKAYPNNYETMKILGSLYaasEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALsayGTATRILQekv 445
Cdd:TIGR02917 761 AWLKTHPNDAVLRTALAELY---LAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRAL---EYAERALK--- 831
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7661950 446 QADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAehdehyynaisvTTSYNLARLYEAMCEFHEAEKLYKNIL 524
Cdd:TIGR02917 832 LAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAA------------AIRYHLALALLATGRKAEARKELDKLL 898
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
5.10e-12 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 70.32 E-value: 5.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSD 1103
Cdd:NF033609 627 DSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SD 705
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 1104 NESVQSGRSHSGvSENDSRPASPS-AESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 706 SDSDSDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 777
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
1.19e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 69.17 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-S 1102
Cdd:NF033609 683 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdS 762
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 1103 DNESVQSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 763 DSDSDSDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 833
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.57e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.78 E-value: 1.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
Cdd:NF033609 608 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 687
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 1109 SGRSHSGVSENDSRPASPSaESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 688 SDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 751
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.80e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.78 E-value: 1.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSDNESVQ 1108
Cdd:NF033609 638 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDS 716
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1109 SGRSHSGvSENDSRPASPS-AESDHESERGSDNEG---SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 717 DSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSDSdsdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 785
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.83e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.78 E-value: 1.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
Cdd:NF033609 676 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 755
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7661950 1109 SGRSHSGVSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 756 SDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 821
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
2.26e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.40 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-SDNESV 1107
Cdd:NF033609 620 SDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSD 699
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 700 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 765
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
3.04e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.01 E-value: 3.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-S 1102
Cdd:NF033609 653 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdS 732
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 1103 DNESVQSGRSHSGvSENDSRPASPS-AESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 733 DSDSDSDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 805
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
3.34e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 68.01 E-value: 3.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSD 1103
Cdd:NF033609 675 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 754
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 1104 NESVQSGRSHSGVSENDSRPASPS---AESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 755 DSDSDSDSDSDSDSDSDSDSDSDSdsdSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 829
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
3.51e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 67.63 E-value: 3.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-SDNESV 1107
Cdd:NF033609 720 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSD 799
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 800 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSESDSNsDSE 865
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1024-1173 |
3.73e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 67.63 E-value: 3.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1024 DKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSD 1103
Cdd:NF033609 645 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SD 723
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 1104 NESVQSGRSHSGV-SENDSRPASPS-AESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 724 SDSDSDSDSDSDSdSDSDSDSDSDSdSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 797
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
3.96e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 67.63 E-value: 3.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-SDNESV 1107
Cdd:NF033609 588 SDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSdSDSDSD 667
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 668 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 733
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
630-750 |
5.50e-11 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 61.75 E-value: 5.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 630 DRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLR 709
Cdd:COG4783 21 DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALK 100
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 7661950 710 KFYKHqnTEVVLYLARALFKCGKLQECKQTLLKARHVAPSD 750
Cdd:COG4783 101 LDPEH--PEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
5.90e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 66.86 E-value: 5.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSE-QSDNESV 1107
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSD 791
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1108 QSGRSHSGvSENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 792 SDSDSDSD-SDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSE 857
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
306-424 |
7.08e-11 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 61.18 E-value: 7.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 306 AESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLpFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLY 385
Cdd:COG4235 17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADA-LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAA 95
|
90 100 110
....*....|....*....|....*....|....*....
gi 7661950 386 AASEDQEKrdiAKGHLKKVTEQYPDDVEaWIELAQILEQ 424
Cdd:COG4235 96 FQQGDYAE---AIAAWQKLLALLPADAP-ARLLEASIAE 130
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1165 |
1.00e-10 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 66.47 E-value: 1.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEqSDNESVQ 1108
Cdd:NF033609 732 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDS 810
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1109 SGRSHSGVSENDSRPASPSAESDHESERGSDNE-GSGQGSGNESEPEGSNNEASDRGS 1165
Cdd:NF033609 811 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSESDSNSDSESGS 868
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
501-594 |
1.30e-10 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 60.40 E-value: 1.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 501 YNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQE 580
Cdd:COG4235 21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGD 100
|
90
....*....|....
gi 7661950 581 WGPGQKKFERILKQ 594
Cdd:COG4235 101 YAEAIAAWQKLLAL 114
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
131-268 |
1.42e-10 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 60.59 E-value: 1.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 131 LLGRACFCLLEGDkMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPaEVRLGMGHCFVK 210
Cdd:COG4783 7 LYALAQALLLAGD-YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP-EARLNLGLALLK 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 211 LNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADsikNGVQLLSRAYTIDPSN 268
Cdd:COG4783 85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPD---EAIAALEKALELDPDD 139
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1173 |
1.53e-10 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 65.70 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSE---QSDNE 1105
Cdd:NF033609 580 SDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDsdsDSDSD 659
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7661950 1106 SVQSGRSHSGV-SENDSRPASPS-AESDHESERGSDNEgSGQGSGNESEPEGSNNEASDRGSEHGSD-DSD 1173
Cdd:NF033609 660 SDSDSDSDSDSdSDSDSDSDSDSdSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSD 729
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
501-646 |
2.41e-10 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 59.82 E-value: 2.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 501 YNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQE 580
Cdd:COG4783 8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGD 87
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 581 WGPGQKKFERILKQPSTQSDTYSMLAlgnvwlqtlhqptrDREKEKRHQDRALAIYKQVLRNDAKN 646
Cdd:COG4783 88 YDEALALLEKALKLDPEHPEAYLRLA--------------RAYRALGRPDEAIAALEKALELDPDD 139
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
625-764 |
4.22e-10 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 62.05 E-value: 4.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 625 EKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMY 704
Cdd:COG2956 20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 705 ENCLRKfyKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRL 764
Cdd:COG2956 100 EKLLEL--DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ 157
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
1029-1172 |
5.90e-10 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 63.77 E-value: 5.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ---SDNE 1105
Cdd:NF033609 750 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdSDSD 829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1106 SVQSGRSHSGvSENDSRPASPSA-ESDHESERGSDNEG-------------SGQGSGNESEPEGSNNEASDRGSEHGSDD 1171
Cdd:NF033609 830 SDSDSDSDSD-SDSDSDSDSDSDsDSDSESDSNSDSESgsnnnvvppnspkNGTNASNKNEAKDSKEPLPDTGSEDEANT 908
|
.
gi 7661950 1172 S 1172
Cdd:NF033609 909 S 909
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
225-476 |
1.93e-09 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 59.64 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 225 LELNSKCVGALVGLAVLELNNKEADsikNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKvqhlALHAFHNT-EVEA 303
Cdd:COG0457 1 LELDPDDAEAYNNLGLAYRRLGRYE---EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEE----ALADYEQAlELDP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 304 MQAESCYQLARSFHVQEDYDQAFQYYYQATQfASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGS 383
Cdd:COG0457 74 DDAEALNNLGLALQALGRYEEALEDYDKALE-LDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 384 LYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFR 463
Cdd:COG0457 153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232
|
250
....*....|...
gi 7661950 464 LGNLGEAKKYFLA 476
Cdd:COG0457 233 LRLAALALYQYRA 245
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
515-646 |
2.54e-09 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 56.55 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 515 EAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQ 594
Cdd:COG4235 1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 7661950 595 PSTQSDTYSMLALgnvwlqtlhqptrDREKEKRHqDRALAIYKQVLRNDAKN 646
Cdd:COG4235 81 DPDNPEALYLLGL-------------AAFQQGDY-AEAIAAWQKLLALLPAD 118
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
347-434 |
2.66e-09 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 56.55 E-value: 2.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 347 LGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQT- 425
Cdd:COG4235 23 LGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEE---AEELLERALALDPDNPEALYLLGLAAFQQg 99
|
....*....
gi 7661950 426 DIQGALSAY 434
Cdd:COG4235 100 DYAEAIAAW 108
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
32-260 |
3.34e-09 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 59.36 E-value: 3.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 32 SILKQEHTQLHIWIALALEYYKQGKTEEFVKLLEAARidgnldyrDHEKDQMTCLDTLAAYYVQQARKEknkdnkkdlit 111
Cdd:COG2956 67 KLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL--------ELDPDDAEALRLLAEIYEQEGDWE----------- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 112 QATLLYTMADKIIMYDQNHLLGRACFCLLEGDKmDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALR 191
Cdd:COG2956 128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDY-DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7661950 192 TNPGcPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNGVQLLSR 260
Cdd:COG2956 207 QDPD-YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRR 274
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
345-530 |
5.28e-09 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 55.97 E-value: 5.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 345 FGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILeq 424
Cdd:COG4783 8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDE---AIVLLHEALELDPDEPEARLNLGLAL-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 425 tdiqgalsaygtatrilqekvqadvppeilnnvgalhFRLGNLGEAKKYFLASLdraKAEAEHDEHYynaisvttsYNLA 504
Cdd:COG4783 83 -------------------------------------LKAGDYDEALALLEKAL---KLDPEHPEAY---------LRLA 113
|
170 180
....*....|....*....|....*.
gi 7661950 505 RLYEAMCEFHEAEKLYKNILREHPNY 530
Cdd:COG4783 114 RAYRALGRPDEAIAALEKALELDPDD 139
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
506-593 |
8.37e-09 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 54.02 E-value: 8.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 506 LYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDwFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQ 585
Cdd:COG3063 1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79
|
....*...
gi 7661950 586 KKFERILK 593
Cdd:COG3063 80 AYLERALE 87
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
164-277 |
3.60e-08 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 53.66 E-value: 3.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 164 PALLGKACISFNKKDYRGALAYYKKALRTNPGcPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLEL 243
Cdd:COG4783 5 EALYALAQALLLAGDYDEAEALLEKALELDPD-NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83
|
90 100 110
....*....|....*....|....*....|....
gi 7661950 244 NNKEADsikNGVQLLSRAYTIDPSNPMVLNHLAN 277
Cdd:COG4783 84 KAGDYD---EALALLEKALKLDPEHPEAYLRLAR 114
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
156-269 |
3.66e-08 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 53.09 E-value: 3.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 156 LNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGcPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGAL 235
Cdd:COG4235 10 LAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPD-NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL 88
|
90 100 110
....*....|....*....|....*....|....
gi 7661950 236 VGLAVLELNNKEADsikNGVQLLSRAYTIDPSNP 269
Cdd:COG4235 89 YLLGLAAFQQGDYA---EAIAAWQKLLALLPADA 119
|
|
| COG4700 |
COG4700 |
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown]; |
664-849 |
4.09e-08 |
|
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
Pssm-ID: 443735 [Multi-domain] Cd Length: 249 Bit Score: 55.66 E-value: 4.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 664 REARDvfAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHqNTEVVLYLARALFKCGKLQECKQTLLKA 743
Cdd:COG4700 74 RELRE--LEKALEFADTVQNRVRLADALLELGRYDEAIELYEEALTGIFAD-DPHILLGLAQALFELGRYAEALETLEKL 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 744 RHVAP----SDTVLMFnvALVLQRLAtsvlkdeksnlkEVLNAVKELELAHRYFSY----------LSKVGDKmrfdlal 809
Cdd:COG4700 151 IAKNPdfksSDAHLLY--ARALEALG------------DLEAAEAELEALARRYSGpearyryakfLARQGRT------- 209
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 7661950 810 aaTEAR-QCSDLLSQAQYHVARARKQDEEERElRAKQEQEK 849
Cdd:COG4700 210 --AEAKeLLEEILDEAKHMPKHYRRLNREWIR-EAKKLLKS 247
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
401-542 |
6.22e-08 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 52.70 E-value: 6.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 401 LKKVTEQYPDDVEAWIELAQILEQT-DIQGALSAYGTATRILQEKvqadvpPEILNNVGALHFRLGNLGEAKKYFLASLD 479
Cdd:COG4235 6 LRQALAANPNDAEGWLLLGRAYLRLgRYDEALAAYEKALRLDPDN------ADALLDLAEALLAAGDTEEAEELLERALA 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 480 RAKAEAEhdehyynaisvtTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMAR 542
Cdd:COG4235 80 LDPDNPE------------ALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
208-415 |
7.98e-08 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 56.54 E-value: 7.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 208 FVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSiknGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSK 287
Cdd:COG3914 88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE---ALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 288 VQHLALHAFhntEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFvlPFFGLGQMYIYRGDKENASQCFEKV 367
Cdd:COG3914 165 AIAALRRAL---ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA--DAHSNLLFALRQACDWEVYDRFEEL 239
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 7661950 368 LKAYPNNYETMKILGSLYAASED-QEKRDIAKGHLKKVTEQYPDDVEAW 415
Cdd:COG3914 240 LAALARGPSELSPFALLYLPDDDpAELLALARAWAQLVAAAAAPELPPP 288
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
138-228 |
8.76e-08 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 56.54 E-value: 8.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 138 CLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCpAEVRLGMGHCFVKLNKLEKA 217
Cdd:COG3914 121 LLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDN-AEALNNLGNALQDLGRLEEA 199
|
90
....*....|.
gi 7661950 218 RLAFSRALELN 228
Cdd:COG3914 200 IAAYRRALELD 210
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
362-486 |
1.04e-07 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 51.93 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 362 QCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQTDiqgalsAYGTATRIL 441
Cdd:COG4235 4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDE---ALAAYEKALRLDPDNADALLDLAEALLAAG------DTEEAEELL 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 7661950 442 QEKVQADvP--PEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAE 486
Cdd:COG4235 75 ERALALD-PdnPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
534-710 |
1.20e-07 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 52.12 E-value: 1.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 534 YLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWgpgqkkferilkqpstqsdtysmlalgnvwlq 613
Cdd:COG4783 7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL-------------------------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 614 tlhqptrdrekekrhqDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVE 693
Cdd:COG4783 55 ----------------DEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRA 118
|
170
....*....|....*..
gi 7661950 694 QKQYISAVQMYENCLRK 710
Cdd:COG4783 119 LGRPDEAIAALEKALEL 135
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
319-414 |
2.65e-07 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 50.38 E-value: 2.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 319 QEDYDQAFQYYYQATQFASSSFVLP--FFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDI 396
Cdd:COG1729 6 AGDYDEAIAAFKAFLKRYPNSPLAPdaLYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDK 85
|
90
....*....|....*...
gi 7661950 397 AKGHLKKVTEQYPDDVEA 414
Cdd:COG1729 86 ARATLEELIKKYPDSEAA 103
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
86-228 |
3.65e-07 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 51.11 E-value: 3.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 86 LDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPA 165
Cdd:COG5010 11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 166 LLGKACISFNKKDYRGALAYYKKALRTNPGCPaEVRLGMGHCFVKLNKLEKARLAFSRALELN 228
Cdd:COG5010 91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNP-NAYSNLAALLLSLGQDDEAKAALQRALGTS 152
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
629-748 |
9.41e-07 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 49.96 E-value: 9.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 629 QDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCL 708
Cdd:COG5010 36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 7661950 709 RkfYKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAP 748
Cdd:COG5010 116 A--LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
436-641 |
1.17e-06 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 50.68 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 436 TATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHE 515
Cdd:COG4785 12 LALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 516 AEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQp 595
Cdd:COG4785 92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALEL- 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 7661950 596 sTQSDTYSMLALGNVWLQTLHQPTRDREKE---KRHQ-----DRALAIYKQVLR 641
Cdd:COG4785 171 -DPNDPERALWLYLAERKLDPEKALALLLEdwaTAYLlqgdtEEARELFKLALA 223
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
631-750 |
1.22e-06 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 48.85 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 631 RALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRK 710
Cdd:COG4235 1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 7661950 711 fyKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSD 750
Cdd:COG4235 81 --DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
303-376 |
1.41e-06 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 48.06 E-value: 1.41e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 303 AMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLP--FFGLGQMYIYRGDKENASQCFEKVLKAYPNNYE 376
Cdd:COG1729 27 PLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPdaLLKLGLSYLELGDYDKARATLEELIKKYPDSEA 102
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
460-568 |
1.43e-06 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 47.47 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 460 LHFRLGNLGEAKKYFLASLdrakaeaEHDEHYYNAIsvttsYNLARLYEAMCEFHEAEKlYKNILREHPNYVDCYLRLGA 539
Cdd:COG3063 1 LYLKLGDLEEAEEYYEKAL-------ELDPDNADAL-----NNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAE 67
|
90 100
....*....|....*....|....*....
gi 7661950 540 MARDKGNFYEASDWFKEALQINqdhPDAW 568
Cdd:COG3063 68 LLLELGDYDEALAYLERALELD---PSAL 93
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
644-765 |
1.46e-06 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 49.03 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 644 AKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFykHQNTEVVLYL 723
Cdd:COG4783 1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD--PDEPEARLNL 78
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 7661950 724 ARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLA 765
Cdd:COG4783 79 GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
459-593 |
1.62e-06 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 49.19 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 459 ALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLG 538
Cdd:COG5010 16 LLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLA 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 539 AMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILK 593
Cdd:COG5010 96 LLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
|
|
| TPR_12 |
pfam13424 |
Tetratricopeptide repeat; |
453-521 |
2.21e-06 |
|
Tetratricopeptide repeat;
Pssm-ID: 315987 [Multi-domain] Cd Length: 77 Bit Score: 46.61 E-value: 2.21e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7661950 453 ILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDehyyNAISVTTSYNLARLYEAMCEFHEAEKLYK 521
Cdd:pfam13424 5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPD----HPLTATTLLNLGRLYLELGRYEEALELLE 69
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
138-230 |
2.40e-06 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 47.09 E-value: 2.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 138 CLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAyYKKALRTNPGCPaEVRLGMGHCFVKLNKLEKA 217
Cdd:COG3063 1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNA-EALLNLAELLLELGDYDEA 78
|
90
....*....|...
gi 7661950 218 RLAFSRALELNSK 230
Cdd:COG3063 79 LAYLERALELDPS 91
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
137-226 |
2.64e-06 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 47.29 E-value: 2.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 137 FCLLEGDKMDQADAQFHFVLNQSPNNI---PALLGKACISFNKKDYRGALAYYKKALRTNPGCP--AEVRLGMGHCFVKL 211
Cdd:COG1729 1 KALLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkaPDALLKLGLSYLEL 80
|
90
....*....|....*
gi 7661950 212 NKLEKARLAFSRALE 226
Cdd:COG1729 81 GDYDKARATLEELIK 95
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
630-710 |
3.03e-06 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 46.70 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 630 DRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDvFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLR 709
Cdd:COG3063 9 EEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALE 87
|
.
gi 7661950 710 K 710
Cdd:COG3063 88 L 88
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
630-709 |
5.85e-06 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 46.92 E-value: 5.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 630 DRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLR 709
Cdd:COG4235 34 DEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA 113
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
229-374 |
6.49e-06 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 47.11 E-value: 6.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 229 SKCVGALVGLAVLELNNKEADSiknGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKvqhlALHAFHN-TEVEAMQAE 307
Cdd:COG4783 1 AACAEALYALAQALLLAGDYDE---AEALLEKALELDPDNPEAFALLGEILLQLGDLDE----AIVLLHEaLELDPDEPE 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7661950 308 SCYQLARSFHVQEDYDQAFQYYYQATQfASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNN 374
Cdd:COG4783 74 ARLNLGLALLKAGDYDEALALLEKALK-LDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
|
|
| DMP1 |
pfam07263 |
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix ... |
1040-1166 |
9.43e-06 |
|
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth specific protein initially identified from mineralized dentin. DMP1 is primarily localized in the nuclear compartment of undifferentiated osteoblasts. In the nucleus, DMP1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the early phase of osteoblast maturation, Ca(2+) surges into the nucleus from the cytoplasm, triggering the phosphorylation of DMP1 by a nuclear isoform of casein kinase II. This phosphorylated DMP1 is then exported out into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP1 is a unique molecule that initiates osteoblast differentiation by transcription in the nucleus and orchestrates mineralized matrix formation extracellularly, at later stages of osteoblast maturation. The DMP1 gene has been found to be ectopically expressed in lung cancer although the reason for this is unknown.
Pssm-ID: 462128 [Multi-domain] Cd Length: 519 Bit Score: 49.54 E-value: 9.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1040 NSDSDEDEQRKKCASSESDSDENQnksgseagsprrprrqrsdQDSDSDQPSRKRRPSG-SEQSDNESVQSGR-SHSGVS 1117
Cdd:pfam07263 379 DSDSSEEDSLSTFSSSESESREEQ-------------------ADSESNESLRSSEESPeSSEDENSSSQEGLqSHSAST 439
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 7661950 1118 ENDSRPASPSAESDHESERGSDNEGSGQGSgnesepEGSNNEASDRGSE 1166
Cdd:pfam07263 440 ESQSEESQSEQDSQSEEDDESDSQDSSRSK------EDSNSTESTSSSE 482
|
|
| TPR_12 |
pfam13424 |
Tetratricopeptide repeat; |
498-563 |
9.99e-06 |
|
Tetratricopeptide repeat;
Pssm-ID: 315987 [Multi-domain] Cd Length: 77 Bit Score: 44.69 E-value: 9.99e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 498 TTSYNLARLYEAMCEFHEAEKLYKNILR--------EHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQD 563
Cdd:pfam13424 4 TALNNLAAVLRRLGRYDEALELLEKALEiarrllgpDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
310-437 |
1.27e-05 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 46.49 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 310 YQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASE 389
Cdd:COG5010 23 LVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSG 102
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 7661950 390 DQEKrdiAKGHLKKVTEQYPDDVEAWIELAQILEQT-DIQGALSAYGTA 437
Cdd:COG5010 103 DKDE---AKEYYEKALALSPDNPNAYSNLAALLLSLgQDDEAKAALQRA 148
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
160-269 |
2.18e-05 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 47.22 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 160 PNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCpAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALV--G 237
Cdd:COG4785 70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDL-AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLnrG 148
|
90 100 110
....*....|....*....|....*....|..
gi 7661950 238 LAVLELNNKEAdsiknGVQLLSRAYTIDPSNP 269
Cdd:COG4785 149 IALYYLGRYEL-----AIADLEKALELDPNDP 175
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
416-561 |
3.91e-05 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 45.34 E-value: 3.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 416 IELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFlaslDRAKAEAEHDEHYYNai 495
Cdd:COG5010 19 KLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALL----EQALQLDPNNPELYY-- 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 496 svttsyNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQIN 561
Cdd:COG5010 93 ------NLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
|
|
| SEEEED |
pfam14797 |
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly ... |
1041-1154 |
5.21e-05 |
|
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly serine-rich region lies on clathrin-adaptor complex 3 beta-1 subunit proteins, between family Adaptin_N, pfam01602 and a C-terminal domain, AP3B1_C,pfam14796.
Pssm-ID: 434218 [Multi-domain] Cd Length: 111 Bit Score: 43.76 E-value: 5.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1041 SDSDEDEqrkkcASSESDSDeNQNKSGSEAGSPRRPRRQRSdqDSDSDQPSRKRRPSGSEqSDNESVQSgRSHSGVSEND 1120
Cdd:pfam14797 7 SESEEEE-----DSSDSSSD-SESESGSESEEEGKEGSSSE--DSSEDSSSEQESESGSE-SEKKRTAK-RNSKAKGKSD 76
|
90 100 110
....*....|....*....|....*....|....
gi 7661950 1121 SRPASPSAESDHESERGSDNEGSGQGSGNESEPE 1154
Cdd:pfam14797 77 SEDGEKKNEKSKTSDSSDTESSSSEESSSDSESE 110
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
34-249 |
5.38e-05 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 46.15 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 34 LKQEHTQLHIWIALALEYYKQGKTEEFVKLLEAA-RIDGNLdyrdhekdqmtcldtlaayyvqqarkeknkdnkkdlitq 112
Cdd:COG0457 1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKAlELDPDD--------------------------------------- 41
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 113 ATLLYTMADkiimydqnhllgracfCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRT 192
Cdd:COG0457 42 AEALYNLGL----------------AYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL 105
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 7661950 193 NPGCpAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEAD 249
Cdd:COG0457 106 DPDD-AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
144-248 |
5.42e-05 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 45.68 E-value: 5.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 144 KMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGcPAEVRLGMGHCFVKLNKLEKARLAFSR 223
Cdd:COG4785 88 DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD-YAYAYLNRGIALYYLGRYELAIADLEK 166
|
90 100
....*....|....*....|....*..
gi 7661950 224 ALELNSKCVGALV--GLAVLELNNKEA 248
Cdd:COG4785 167 ALELDPNDPERALwlYLAERKLDPEKA 193
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
131-228 |
5.96e-05 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 43.84 E-value: 5.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 131 LLGRAcfcLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPaEVRLGMGHCFVK 210
Cdd:COG4235 22 LLGRA---YLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP-EALYLLGLAAFQ 97
|
90
....*....|....*...
gi 7661950 211 LNKLEKARLAFSRALELN 228
Cdd:COG4235 98 QGDYAEAIAAWQKLLALL 115
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
112-266 |
7.12e-05 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 44.57 E-value: 7.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 112 QATLLYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALR 191
Cdd:COG5010 3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 192 TNPGCPaEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSIKngvQLLSRAYTIDP 266
Cdd:COG5010 83 LDPNNP-ELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAK---AALQRALGTSP 153
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
627-793 |
8.11e-05 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 45.29 E-value: 8.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 627 RHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYEN 706
Cdd:COG4785 53 LAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDR 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 707 CLRKfyKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLA-TSVLKDEKSNLKEVLNAVKE 785
Cdd:COG4785 133 ALEL--DPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDpEKALALLLEDWATAYLLQGD 210
|
....*...
gi 7661950 786 LELAHRYF 793
Cdd:COG4785 211 TEEARELF 218
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
656-749 |
1.21e-04 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 42.08 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 656 VLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQmYENCLRkfYKHQNTEVVLYLARALFKCGKLQE 735
Cdd:COG3063 1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALK--LDPNNAEALLNLAELLLELGDYDE 77
|
90
....*....|....
gi 7661950 736 CKQTLLKARHVAPS 749
Cdd:COG3063 78 ALAYLERALELDPS 91
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
301-409 |
1.46e-04 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 43.41 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 301 VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLpFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKI 380
Cdd:COG5010 49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL-YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSN 127
|
90 100
....*....|....*....|....*....
gi 7661950 381 LGSLYAASEDQEKrdiAKGHLKKVTEQYP 409
Cdd:COG5010 128 LAALLLSLGQDDE---AKAALQRALGTSP 153
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
1029-1168 |
1.54e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 45.73 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1029 ADEGHpRNSNSNSDSDEDEQRkkcASSESDSDENQNKSGSEAGsprrprrqrsdqDSDSDQPSRKRRPSGS----EQSDN 1104
Cdd:PHA03169 62 AEQGH-RQTESDTETAEESRH---GEKEERGQGGPSGSGSESV------------GSPTPSPSGSAEELASglspENTSG 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 1105 ESVQSGRSHSGVSENDSRP--ASPSAESDHESERGSDNEGSGQGSGNES--EPEGSNNEASDRGSEHG 1168
Cdd:PHA03169 126 SSPESPASHSPPPSPPSHPgpHEPAPPESHNPSPNQQPSSFLQPSHEDSpeEPEPPTSEPEPDSPGPP 193
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
145-295 |
2.04e-04 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 43.03 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 145 MDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRA 224
Cdd:COG5010 1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7661950 225 LELNSKCVGALVGLAVLELNNKEADSiknGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHA 295
Cdd:COG5010 81 LQLDPNNPELYYNLALLYSRSGDKDE---AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRA 148
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
625-727 |
2.35e-04 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 41.90 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 625 EKRHQDRALAIYKQVLRNDAKNLYAAN---GIGAVLAHKGYFREARDVFAQVREATAD---ISDVWLNLAHIYVEQKQYI 698
Cdd:COG1729 5 KAGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYD 84
|
90 100
....*....|....*....|....*....
gi 7661950 699 SAVQMYENCLRKFYKHQNTEVVLYLARAL 727
Cdd:COG1729 85 KARATLEELIKKYPDSEAAKEARARLARL 113
|
|
| SEEEED |
pfam14797 |
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly ... |
1037-1138 |
3.23e-04 |
|
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly serine-rich region lies on clathrin-adaptor complex 3 beta-1 subunit proteins, between family Adaptin_N, pfam01602 and a C-terminal domain, AP3B1_C,pfam14796.
Pssm-ID: 434218 [Multi-domain] Cd Length: 111 Bit Score: 41.45 E-value: 3.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1037 SNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGsprrprrqrsdqdSDS-DQPSRKRRPSGSEQSDNESVQSGRSHSG 1115
Cdd:pfam14797 22 SESESGSESEEEGKEGSSSEDSSEDSSSEQESESG-------------SESeKKRTAKRNSKAKGKSDSEDGEKKNEKSK 88
|
90 100
....*....|....*....|...
gi 7661950 1116 VSENDSRPASPSAESDHESERGS 1138
Cdd:pfam14797 89 TSDSSDTESSSSEESSSDSESES 111
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
351-440 |
3.95e-04 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 40.54 E-value: 3.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 351 YIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAAsedQEKRDIAKGhLKKVTEQYPDDVEAWIELAQILEQT-DIQG 429
Cdd:COG3063 2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLE---QGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELgDYDE 77
|
90
....*....|.
gi 7661950 430 ALSAYGTATRI 440
Cdd:COG3063 78 ALAYLERALEL 88
|
|
| tol_pal_ybgF |
TIGR02795 |
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ... |
310-420 |
4.21e-04 |
|
tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.
Pssm-ID: 188247 [Multi-domain] Cd Length: 117 Bit Score: 41.11 E-value: 4.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 310 YQLARSFHVQEDYDQA---FQYYyqATQFASSSFV-LPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNY---ETMKILG 382
Cdd:TIGR02795 4 YDAALLVLKAGDYADAiqaFQAF--LKKYPKSTYApNAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSPkapDALLKLG 81
|
90 100 110
....*....|....*....|....*....|....*...
gi 7661950 383 SLYAASEDQEKrdiAKGHLKKVTEQYPDDVEAwiELAQ 420
Cdd:TIGR02795 82 MSLQELGDKEK---AKATLQQVIKRYPGSSAA--KLAQ 114
|
|
| TPR_16 |
pfam13432 |
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ... |
501-565 |
5.26e-04 |
|
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.
Pssm-ID: 433202 [Multi-domain] Cd Length: 68 Bit Score: 39.63 E-value: 5.26e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7661950 501 YNLARLYEAMCEFHEAEKLYKNILR---EHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHP 565
Cdd:pfam13432 1 LALARAALRAGDYDDAAAALEAALArfpESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
512-594 |
5.63e-04 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 40.75 E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 512 EFHEAEKLYKNILREHPN---YVDCYLRLGAMARDKGNFYEASDWFKEALQINQDH---PDAWSLIGNLHLAKQEWGPGQ 585
Cdd:COG1729 8 DYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDYDKAR 87
|
....*....
gi 7661950 586 KKFERILKQ 594
Cdd:COG1729 88 ATLEELIKK 96
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
422-528 |
5.79e-04 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 41.87 E-value: 5.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 422 LEQTDIQGALSAYGTATRILQEKvqadvpPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEhdehyynaisvtTSY 501
Cdd:COG5010 65 NKLGDFEESLALLEQALQLDPNN------PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN------------AYS 126
|
90 100
....*....|....*....|....*..
gi 7661950 502 NLARLYEAMCEFHEAEKLYKNILREHP 528
Cdd:COG5010 127 NLAALLLSLGQDDEAKAALQRALGTSP 153
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
198-332 |
7.66e-04 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 40.95 E-value: 7.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 198 AEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSiknGVQLLSRAYTIDPSNPMVLNHLAN 277
Cdd:COG4783 4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDE---AIVLLHEALELDPDEPEARLNLGL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 7661950 278 HFFFKKDYSKVQHLALHAFhntEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQA 332
Cdd:COG4783 81 ALLKAGDYDEALALLEKAL---KLDPEHPEAYLRLARAYRALGRPDEAIAALEKA 132
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
182-387 |
7.91e-04 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 40.76 E-value: 7.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 182 ALAYYKKALRTNPGCpAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADsikNGVQLLSRA 261
Cdd:COG4235 2 AIARLRQALAANPND-AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTE---EAEELLERA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 262 YTIDPSNPMVLnhlanhfffkkdyskvqhlalhafhnteveamqaescYQLARSFHVQEDYDQAFQYYyqatqfasssfv 341
Cdd:COG4235 78 LALDPDNPEAL-------------------------------------YLLGLAAFQQGDYAEAIAAW------------ 108
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 7661950 342 lpffglgqmyiyrgdkenasqcfEKVLKAYPNNYETMKILGSLYAA 387
Cdd:COG4235 109 -----------------------QKLLALLPADAPARLLEASIAEA 131
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
207-287 |
8.96e-04 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 39.77 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 207 CFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSikngVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYS 286
Cdd:COG3063 1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE----AIALEKALKLDPNNAEALLNLAELLLELGDYD 76
|
.
gi 7661950 287 K 287
Cdd:COG3063 77 E 77
|
|
| COG4700 |
COG4700 |
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown]; |
311-443 |
1.28e-03 |
|
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
Pssm-ID: 443735 [Multi-domain] Cd Length: 249 Bit Score: 41.79 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 311 QLARSFHVQEDYDQAFQYYYQATQ--FASSSFVLpfFGLGQMYIYRGDKENASQCFEKVLKAYP--NNYETMKILGSLYA 386
Cdd:COG4700 94 RLADALLELGRYDEAIELYEEALTgiFADDPHIL--LGLAQALFELGRYAEALETLEKLIAKNPdfKSSDAHLLYARALE 171
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 7661950 387 ASEDQEKrdiAKGHLKKVTEQYPdDVEAWIELAQILEQTDIQGAlsaygtATRILQE 443
Cdd:COG4700 172 ALGDLEA---AEAELEALARRYS-GPEARYRYAKFLARQGRTAE------AKELLEE 218
|
|
| HemYx |
COG3071 |
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ... |
390-645 |
1.47e-03 |
|
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];
Pssm-ID: 442305 [Multi-domain] Cd Length: 323 Bit Score: 42.20 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 390 DQEKRDiakGHLKKVTEQYPDDVEAwIELAQI---LEQTDIQGALSA-------YGTATRILQEKVQADV----PPEILN 455
Cdd:COG3071 65 DYERRD---EYLAQALELAPEAELA-VLLTRAellLDQGQAEQALATlealragAPRHPQVLRLLLQAYRqlgdWEELLE 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 456 NVGALHfRLGNLGEA------KKYFLASLDRAKAEAEHDEHYYNAISVTTSYN------LARLYEAMCEFHEAEKLYKNI 523
Cdd:COG3071 141 LLPALR-KHKALSAEeaqaleRRAYLGLLRQAARDAEALKALWKALPRAERRDpelaaaYARALIALGDHDEAERLLREA 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 524 LREHPN--YVDCYLRLGAMARDKgnfyeASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQpstQSDT 601
Cdd:COG3071 220 LKRQWDprLVRLYGRLQGGDPAK-----QLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALAL---RPSA 291
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 7661950 602 YSMLALGNVWLQTlhqptrdrekekRHQDRALAIYKQVLRNDAK 645
Cdd:COG3071 292 EAYAELARLLEQL------------GDPEEAAEHYRKALALALG 323
|
|
| TPR_19 |
pfam14559 |
Tetratricopeptide repeat; |
177-228 |
1.60e-03 |
|
Tetratricopeptide repeat;
Pssm-ID: 434038 [Multi-domain] Cd Length: 65 Bit Score: 37.95 E-value: 1.60e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 7661950 177 KDYRGALAYYKKALRTNPGCPaEVRLGMGHCFVKLNKLEKARLAFSRALELN 228
Cdd:pfam14559 2 GDYAEALELLEQALAEDPDNA-EARLGLAEALLALGRLDEAEALLAALPAAD 52
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
657-740 |
1.63e-03 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 39.59 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 657 LAHKGYFREARDVFAQVREATAD---ISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNT-EVVLYLARALFKCGK 732
Cdd:COG1729 3 LLKAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApDALLKLGLSYLELGD 82
|
....*...
gi 7661950 733 LQECKQTL 740
Cdd:COG1729 83 YDKARATL 90
|
|
| DMP1 |
pfam07263 |
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix ... |
1032-1169 |
2.14e-03 |
|
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth specific protein initially identified from mineralized dentin. DMP1 is primarily localized in the nuclear compartment of undifferentiated osteoblasts. In the nucleus, DMP1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the early phase of osteoblast maturation, Ca(2+) surges into the nucleus from the cytoplasm, triggering the phosphorylation of DMP1 by a nuclear isoform of casein kinase II. This phosphorylated DMP1 is then exported out into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP1 is a unique molecule that initiates osteoblast differentiation by transcription in the nucleus and orchestrates mineralized matrix formation extracellularly, at later stages of osteoblast maturation. The DMP1 gene has been found to be ectopically expressed in lung cancer although the reason for this is unknown.
Pssm-ID: 462128 [Multi-domain] Cd Length: 519 Bit Score: 42.22 E-value: 2.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1032 GHPRNSNSNSDSDEDEQRKKCASSESDSDenqNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGR 1111
Cdd:pfam07263 89 GLSRSGGKEGDDKDDDEDDSGDDTFGDED---NGPGPEERQEGGNSRLGSDEDSADTTQSREDSASQGEDSAQDTTSESR 165
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 1112 SHSGVSENDSRPASPSAESDHESE---RGSDNEG-SGQGSGNESEPEGSNNEASDR-GSEHGS 1169
Cdd:pfam07263 166 DLDNEDEVSSRPESGDSTQDSESEehwVGGGSEGdSSHGDGSEFDDEGMQSDDPDSiRSERGN 228
|
|
| HemYx |
COG3071 |
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ... |
280-581 |
2.24e-03 |
|
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];
Pssm-ID: 442305 [Multi-domain] Cd Length: 323 Bit Score: 41.43 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 280 FFKKDYSKVQHLALHAFHNTEVEAMqaesCYQL-ARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKE 358
Cdd:COG3071 27 LAEGRYARAEKLLSKAAEHSEAPLL----AYLLaARAAQALGDYERRDEYLAQALELAPEAELAVLLTRAELLLDQGQAE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 359 NASQCFEKVLKAYPNNYETMKILGSLYAASED-QEKRDIAKgHLKKVTEQYPDDVEAWIELAqileqtdIQGALSAYGTA 437
Cdd:COG3071 103 QALATLEALRAGAPRHPQVLRLLLQAYRQLGDwEELLELLP-ALRKHKALSAEEAQALERRA-------YLGLLRQAARD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 438 TRILQEkVQADVPPEILNNVG-ALHF-----RLGNLGEAKKYFLASLDRakaeaEHDEHyynaisvttsynLARLYEAmC 511
Cdd:COG3071 175 AEALKA-LWKALPRAERRDPElAAAYaraliALGDHDEAERLLREALKR-----QWDPR------------LVRLYGR-L 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 512 EFHEAEKLYKNI---LREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDhPDAWSLIGNLHLAKQEW 581
Cdd:COG3071 236 QGGDPAKQLKRAekwLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDP 307
|
|
| dermokine |
cd21118 |
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
1032-1169 |
2.33e-03 |
|
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.
Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 41.91 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 1032 GHPRNSNSNSD------SDEDEqrkkcASSESDSDENqnkSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNe 1105
Cdd:cd21118 191 GTVRGNNQNSGctnpppSGSHE-----SFSNSGGSSS---SGSSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSGN- 261
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7661950 1106 svqSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEgSNNEASDRGSEHGS 1169
Cdd:cd21118 262 ---SGGSNGGSSGNSGSGSGGSSSGGSNGWGGSSSSGGSGGSGGGNKPE-CNNPGNDVRMAGGG 321
|
|
| TPR_19 |
pfam14559 |
Tetratricopeptide repeat; |
512-574 |
2.39e-03 |
|
Tetratricopeptide repeat;
Pssm-ID: 434038 [Multi-domain] Cd Length: 65 Bit Score: 37.56 E-value: 2.39e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7661950 512 EFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNL 574
Cdd:pfam14559 3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
629-764 |
2.58e-03 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 39.94 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 629 QDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCL 708
Cdd:COG5010 2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 7661950 709 RKFYKhqNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRL 764
Cdd:COG5010 82 QLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSL 135
|
|
| ACL4-like |
cd24142 |
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ... |
349-447 |
4.92e-03 |
|
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.
Pssm-ID: 467942 [Multi-domain] Cd Length: 306 Bit Score: 40.30 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 349 QMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKrdiAKGHLKKVTEQYPDD-VEAWIELAQILEQTDi 427
Cdd:cd24142 8 EELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEE---AREVLLRAIELDPDGgYEKYLYLGQLSGGEE- 83
|
90 100
....*....|....*....|
gi 7661950 428 qgALSAYGTATRILQEKVQA 447
Cdd:cd24142 84 --ALQYYEKGIEILEEELQA 101
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
176-369 |
4.93e-03 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 39.90 E-value: 4.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 176 KKDYRGALAYYKKALRTNPGCPAEVRLGMghCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSiknGV 255
Cdd:COG4785 53 LAAAALAAERIDRALALPDLAQLYYERGV--AYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA---AL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7661950 256 QLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARsfhvQEDYDQAFQYYYQATQF 335
Cdd:COG4785 128 EDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAER----KLDPEKALALLLEDWAT 203
|
170 180 190
....*....|....*....|....*....|....
gi 7661950 336 AsssfvlpffglgqmYIYRGDKENASQCFEKVLK 369
Cdd:COG4785 204 A--------------YLLQGDTEEARELFKLALA 223
|
|
| |
