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Conserved domains on  [gi|49355721|ref|NP_055182|]
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protein FAM162A [Homo sapiens]

Protein Classification

FAM162A family protein( domain architecture ID 10533950)

FAM162A (family with sequence similarity 162 member A) family protein; FAM162A also known as human growth and transformation-dependent protein (HGTD-P), is a hypoxia-inducible factor-1a (HIF-1a)-responsive protein which promotes intrinsic (mitochondrial mediated) apoptosis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1075 pfam06388
Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of ...
 16-133 1.09e-66

Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of unknown function.


:

Pssm-ID: 461893  Cd Length: 124  Bit Score: 198.33  E-value: 1.09e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49355721    16 RLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGAPS------RTYNRVPLHKPTDWQKKILIWSGRFKKEDEIPETVSL 89
Cdd:pfam06388   1 RLCERGASSTLRLTRNTDLKRIRGLCTKPQESSGAPPsstvavRPVHRVPGHKPTDFDKKILLWSGRFKKEEDIPETVSF 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 49355721    90 EMLDAAKNKMRVKISYLMIALTVVGCIFMVIEGKKAAQRHETLT 133
Cdd:pfam06388  81 EMIDAAKNKARVKACYIMIALTIVGCIAMVISGKRAVKRHESLT 124
 
Name Accession Description Interval E-value
DUF1075 pfam06388
Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of ...
 16-133 1.09e-66

Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of unknown function.


Pssm-ID: 461893  Cd Length: 124  Bit Score: 198.33  E-value: 1.09e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49355721    16 RLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGAPS------RTYNRVPLHKPTDWQKKILIWSGRFKKEDEIPETVSL 89
Cdd:pfam06388   1 RLCERGASSTLRLTRNTDLKRIRGLCTKPQESSGAPPsstvavRPVHRVPGHKPTDFDKKILLWSGRFKKEEDIPETVSF 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 49355721    90 EMLDAAKNKMRVKISYLMIALTVVGCIFMVIEGKKAAQRHETLT 133
Cdd:pfam06388  81 EMIDAAKNKARVKACYIMIALTIVGCIAMVISGKRAVKRHESLT 124
 
Name Accession Description Interval E-value
DUF1075 pfam06388
Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of ...
 16-133 1.09e-66

Protein of unknown function (DUF1075); This family consists of several eukaryotic proteins of unknown function.


Pssm-ID: 461893  Cd Length: 124  Bit Score: 198.33  E-value: 1.09e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49355721    16 RLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGAPS------RTYNRVPLHKPTDWQKKILIWSGRFKKEDEIPETVSL 89
Cdd:pfam06388   1 RLCERGASSTLRLTRNTDLKRIRGLCTKPQESSGAPPsstvavRPVHRVPGHKPTDFDKKILLWSGRFKKEEDIPETVSF 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 49355721    90 EMLDAAKNKMRVKISYLMIALTVVGCIFMVIEGKKAAQRHETLT 133
Cdd:pfam06388  81 EMIDAAKNKARVKACYIMIALTIVGCIAMVISGKRAVKRHESLT 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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