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Conserved domains on  [gi|37594471|ref|NP_055177|]
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3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform 1 precursor [Homo sapiens]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-376 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 557.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV-FFREEYML 124
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFILEEHMDKINSCFSANTVEEIIENL 284
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   285 QQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 362
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 37594471   363 DLKEVTEEDLNNHF 376
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-376 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 557.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV-FFREEYML 124
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFILEEHMDKINSCFSANTVEEIIENL 284
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   285 QQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 362
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 37594471   363 DLKEVTEEDLNNHF 376
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
34-378 4.07e-159

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 450.43  E-value: 4.07e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKI 113
Cdd:PRK05617   1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 192
Cdd:PRK05617  81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  193 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfiLEEHMDKINSC 271
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  272 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLI 351
Cdd:PRK05617 236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLI 315
                        330       340
                 ....*....|....*....|....*..
gi 37594471  352 DKDQSPKWKPADLKEVTEEDLNNHFKS 378
Cdd:PRK05617 316 DKDRNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-222 6.53e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 194.70  E-value: 6.53e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIApVF 117
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:cd06558  79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                       170       180
                ....*....|....*....|....*.
gi 37594471 197 LTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:cd06558 159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
38-350 1.49e-51

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 172.66  E-value: 1.49e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQkiAPVF 117
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEE--ARAF 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:COG1024  78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 197 LTGFRLKGRDVYRAGIATHFVDSEKLamLEEdllalkspskeniasvlenyhteskidrdksfileehmdkinscfsant 276
Cdd:COG1024 158 LTGRRIDAEEALELGLVNRVVPDDEL--LAA------------------------------------------------- 186
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 37594471 277 veeiienlqqdgssfALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 350
Cdd:COG1024 187 ---------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
26-222 1.39e-14

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 72.96  E-value: 1.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    26 LRMSKHTDAAEEvllekkgctgvITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 105
Cdd:TIGR01929   4 IRYEKSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRGD 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   106 AEKAKQKIAPVFFREEymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP 185
Cdd:TIGR01929  73 YGYIDDSGVHRLNVLD--VQRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMA 150
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 37594471   186 RLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:TIGR01929 151 RIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-376 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 557.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV-FFREEYML 124
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFILEEHMDKINSCFSANTVEEIIENL 284
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   285 QQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 362
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 37594471   363 DLKEVTEEDLNNHF 376
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
34-378 4.07e-159

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 450.43  E-value: 4.07e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKI 113
Cdd:PRK05617   1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 192
Cdd:PRK05617  81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  193 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfiLEEHMDKINSC 271
Cdd:PRK05617 161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  272 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLI 351
Cdd:PRK05617 236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLI 315
                        330       340
                 ....*....|....*....|....*..
gi 37594471  352 DKDQSPKWKPADLKEVTEEDLNNHFKS 378
Cdd:PRK05617 316 DKDRNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
34-377 1.14e-112

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 334.08  E-value: 1.14e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKI 113
Cdd:PLN02874   9 AEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGRESDDSC 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 APVFFREeYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGY 193
Cdd:PLN02874  88 LEVVYRM-YWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  194 FLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKsfILEEhMDKINSCFS 273
Cdd:PLN02874 167 YLALTGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFSKDVQADEDS--ILNK-QSWINECFS 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  274 ANTVEEIIENLQ----QDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRG---HDFHEGV 346
Cdd:PLN02874 244 KDTVEEIIKAFEseasKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNILRStvsDDVYEGI 323
                        330       340       350
                 ....*....|....*....|....*....|.
gi 37594471  347 RAVLIDKDQSPKWKPADLKEVTEEDLNNHFK 377
Cdd:PLN02874 324 RALVIDKDNAPKWNPSTLDEVTDEKVDLVFQ 354
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
28-379 4.01e-92

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 281.61  E-value: 4.01e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDIR-VISEA 106
Cdd:PLN02988   1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKG-HGRAFCAGGDVAaVVRDI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  107 EKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 186
Cdd:PLN02988  80 EQGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  187 LQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFileEHMD 266
Cdd:PLN02988 160 LPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAY---HRLD 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  267 KINSCFSANTVEEIIENLQ----QDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGH-- 340
Cdd:PLN02988 237 VIDRCFSRRTVEEIISALEreatQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEis 316
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 37594471  341 -DFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSL 379
Cdd:PLN02988 317 kDFVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERV 356
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
18-383 8.44e-88

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 271.47  E-value: 8.44e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   18 RTNTILHHLRMS------KHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGg 91
Cdd:PLN02851  18 RFGSVSYGRSFSalpnyaANDDLQDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   92 KAFCAGGDIRVISEA-EKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPET 170
Cdd:PLN02851  97 RAFCSGADVVSLYHLiNEGNVEECKLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEV 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  171 AIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHte 250
Cdd:PLN02851 177 QMGFHPDAGASYYLSRLPGYLGEYLALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQYG-- 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  251 SKIDRDKSFILEEhMDKINSCFSANTVEEIIENLQQDGSS----FALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVL 326
Cdd:PLN02851 255 DLVYPDKSSVLHK-IETIDKCFGHDTVEEIIEALENEAASsydeWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCL 333
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  327 TMEYRLSQACMR---GHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSD 383
Cdd:PLN02851 334 AREYRISLCGVSkwvSGDFCEGVRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPLDESE 393
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
5-383 5.75e-82

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 256.15  E-value: 5.75e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    5 EMWRLmsrfnAFKRTntiLHHLRMSKHtDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84
Cdd:PLN02157  15 KLWRF-----GYRRS---FCSLKLTPE-DLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   85 IIKGAGgKAFCAGGDIRVISEAE-KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKC 163
Cdd:PLN02157  86 MMKGSG-RAFCAGGDIVSLYHLRkRGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRT 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  164 LFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASV 243
Cdd:PLN02157 165 IFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESC 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  244 LENYhteSKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGS----SFALEQLKVINKMSPTSLKITLRQLMEGSS 319
Cdd:PLN02157 245 LEKC---AEVAHPEKTGVIRRIDLLEKCFSHDTVEEIIDSLEIEAGrrkdTWCITTLRRLKESSPLSLKVALRSIREGRL 321
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 37594471  320 KTLQEVLTMEYRLSQACMRG---HDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSD 383
Cdd:PLN02157 322 QTLDQCLIREYRMSLQGLIGpmsGNFCEGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALTPTE 388
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-222 6.53e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 194.70  E-value: 6.53e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIApVF 117
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:cd06558  79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                       170       180
                ....*....|....*....|....*.
gi 37594471 197 LTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:cd06558 159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
38-350 1.49e-51

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 172.66  E-value: 1.49e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQkiAPVF 117
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEE--ARAF 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:COG1024  78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 197 LTGFRLKGRDVYRAGIATHFVDSEKLamLEEdllalkspskeniasvlenyhteskidrdksfileehmdkinscfsant 276
Cdd:COG1024 158 LTGRRIDAEEALELGLVNRVVPDDEL--LAA------------------------------------------------- 186
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 37594471 277 veeiienlqqdgssfALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 350
Cdd:COG1024 187 ---------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
37-350 1.83e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 130.76  E-value: 1.83e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIrviSEAEKAKQKIAPV 116
Cdd:PRK06688   6 DLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGR-AFSAGGDI---KDFPKAPPKPPDE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  117 FfREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLqgkLGYF-- 194
Cdd:PRK06688  82 L-APVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRL---IGRAra 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  195 --LALTGFRLKGRDVYRAGIATHFVDSEKLAmleedllalkspskeniasvlenyhteskidrdksfileehmdkinscf 272
Cdd:PRK06688 158 aeMLLLGEPLSAEEALRIGLVNRVVPAAELD------------------------------------------------- 188
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 37594471  273 santveeiienlqqdgsSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 350
Cdd:PRK06688 189 -----------------AEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFI 249
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
28-231 6.52e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 107.87  E-value: 6.52e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107
Cdd:PRK06127   3 MSSISSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  108 KAKQKIAPVFFREEYMLnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdvGGGY-FLPR 186
Cdd:PRK06127  83 SDAEAVAAYEQAVEAAQ-AALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL----GYGYdGVKN 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 37594471  187 LQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA 231
Cdd:PRK06127 158 LVDLVGPSAAkdlfYTARRFDAAEALRIGLVHRVTAADDLETALADYAA 206
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
38-241 1.10e-26

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 107.14  E-value: 1.10e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS-----EAEKAKQK 112
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKdlneeEGRKFGLL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  113 IAPVFFREEYMlnnavgscQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KL 191
Cdd:PRK05809  86 GNKVFRKLENL--------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGpGK 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 37594471  192 GYFLALTGFRLKGRDVYRAGIATHFVDSEKLaMLEEDLLALKSPSKENIA 241
Cdd:PRK05809 158 AKELIYTGDMINAEEALRIGLVNKVVEPEKL-MEEAKALANKIAANAPIA 206
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
41-222 1.47e-25

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 103.59  E-value: 1.47e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    41 EKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAKQKIapvfFRE 120
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQAL----YRE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   121 EYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALT 198
Cdd:pfam00378  76 NVLdLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLL 155
                         170       180
                  ....*....|....*....|....
gi 37594471   199 GFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:pfam00378 156 GRRISAQEALKWGLVDKVVPEDQL 179
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
47-245 1.62e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 103.66  E-value: 1.62e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI--RVISEAEKAKQKIAPVffrEEYMl 124
Cdd:PRK07657  15 VKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLkeRAGMNEEQVRHAVSLI---RTTM- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  125 nNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLK 203
Cdd:PRK07657  91 -EMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRIS 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 37594471  204 GRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIASVLE 245
Cdd:PRK07657 170 AQEAKEIGLVEFVVPAHLLEEKAIEIaekIASNGPiavrqAKEAISNGIQ 219
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
37-212 5.81e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 102.16  E-value: 5.81e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE--AEKAKQKIA 114
Cdd:PRK06072   1 MIKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPdfAIDLRETFY 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  115 PVFfREeymlnnaVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF 194
Cdd:PRK06072  80 PII-RE-------IRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYE 151
                        170
                 ....*....|....*...
gi 37594471  195 LALTGFRLKGRDVYRAGI 212
Cdd:PRK06072 152 ILVLGGEFTAEEAERWGL 169
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
33-220 5.95e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 102.44  E-value: 5.95e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   33 DAAEEVLLEKKGcTGV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAK 110
Cdd:PRK08138   4 TATDVVLLERPA-DGValLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATAGAIE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  111 qkiapVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK 190
Cdd:PRK08138  82 -----MYLRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGK 156
                        170       180       190
                 ....*....|....*....|....*....|.
gi 37594471  191 L-GYFLALTGFRLKGRDVYRAGIATHFVDSE 220
Cdd:PRK08138 157 FkAMRMALTGCMVPAPEALAIGLVSEVVEDE 187
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
34-242 2.40e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 100.50  E-value: 2.40e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviseaEKAKQKI 113
Cdd:PRK05862   2 AYETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIK-----EMADLSF 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 APVfFREEYMLN-NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 192
Cdd:PRK05862  76 MDV-YKGDYITNwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAK 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 37594471  193 YF-LALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDLLAlkspsKENIAS 242
Cdd:PRK05862 155 AMdLCLTGRMMDAAEAERAGLVSRVVPADKL--LDEALAA-----ATTIAS 198
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
38-245 2.91e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 100.50  E-value: 2.91e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRviSEAEKAKQKIAPVF 117
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLK--EQAAGGKRGWPESG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  118 FreeymlnnavGS------CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR---LQ 188
Cdd:PRK06494  84 F----------GGltsrfdLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRqigLK 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 37594471  189 GKLGYFlaLTGFRLKGRDVYRAGIATHFV-DSEKLAMLE---EDLLALkSP-----SKENIASVLE 245
Cdd:PRK06494 154 RAMGMI--LTGRRVTAREGLELGFVNEVVpAGELLAAAErwaDDILAC-SPlsiraSKQAVYRGLE 216
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
35-199 3.52e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 100.22  E-value: 3.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIA 114
Cdd:PRK05980   2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  115 PV-FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLG 192
Cdd:PRK05980  82 LRdFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrKRA 161

                 ....*..
gi 37594471  193 YFLALTG 199
Cdd:PRK05980 162 LELLLTG 168
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
38-235 2.74e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 89.37  E-value: 2.74e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEK------AKQ 111
Cdd:PRK06495   6 LKLEVSDHVAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKgpgdlrAHN 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  112 KIAPVFFreeymlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdVGGGYFLPRLQGK- 190
Cdd:PRK06495  84 RRTRECF-------HAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHs 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 37594471  191 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL---AMLEEDLLALKSP 235
Cdd:PRK06495 154 LTRRMMLTGYRVPAAELYRRGVIEACLPPEELmpeAMEIAREIASKSP 201
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
40-245 3.88e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 88.92  E-value: 3.88e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   40 LEKKGCTGVITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVI------SEAEKAKQKI 113
Cdd:PRK07658   6 VRVEDHVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFtsvteaEQATELAQLG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 APVFFREEymlnnavgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-G 192
Cdd:PRK07658  84 QVTFERVE--------KFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAkA 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 37594471  193 YFLALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDL-----LALKSPskENIASVLE 245
Cdd:PRK07658 156 LEMMLTSEPITGAEALKWGLVNGVFPEETL--LDDAKklakkIAGKSP--ATTRAVLE 209
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
35-226 7.43e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 87.86  E-value: 7.43e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEA--EKAKQK 112
Cdd:PRK05870   2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGAApgRPAEDG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  113 IAPVFfrEEYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KL 191
Cdd:PRK05870  81 LRRIY--DGFL---AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGpQV 155
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 37594471  192 GYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 226
Cdd:PRK05870 156 ARAALLFGMRFDAEAAVRHGLALMVADDPVAAALE 190
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
36-236 2.52e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 86.52  E-value: 2.52e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDI---RVISEAEKAKQK 112
Cdd:PRK05995   4 ETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDENR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  113 IAPVFFREeyMLNnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVgggyFLPRLQGKLG 192
Cdd:PRK05995  83 ADARRLAD--MLR-AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPAT----ISPYVIRAMG 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 37594471  193 ------YFlaLTGFRLKGRDVYRAGIATHFVDSEKL-AMLEEDLLAL--KSPS 236
Cdd:PRK05995 156 eraarrYF--LTAERFDAAEALRLGLVHEVVPAEALdAKVDELLAALvaNSPQ 206
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
34-222 2.74e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 86.57  E-value: 2.74e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRvisEAEKAKQKI 113
Cdd:PRK06190   2 TEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGA-DPAFCAGLDLK---ELGGDGSAY 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 APVFFREEymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLG 192
Cdd:PRK06190  78 GAQDALPN--PSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGiGRA 155
                        170       180       190
                 ....*....|....*....|....*....|
gi 37594471  193 YFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK06190 156 RRMSLTGDFLDAADALRAGLVTEVVPHDEL 185
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
49-235 2.92e-19

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 86.88  E-value: 2.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE-------------AEKAKQKIAp 115
Cdd:PLN02664  21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKTLNSiseqsssgdrgrsGERLRRKIK- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  116 vfFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYF- 194
Cdd:PLN02664  99 --FLQDAI--TAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGYGn 171
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 37594471  195 ---LALTGFRLKGRDVYRAG-IATHFVDSEKL---AMLEEDLLALKSP 235
Cdd:PLN02664 172 ameLALTGRRFSGSEAKELGlVSRVFGSKEDLdegVRLIAEGIAAKSP 219
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
49-235 7.77e-19

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 85.20  E-value: 7.77e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRviseaEKAKQKIAPVFFREEYMLNNAV 128
Cdd:PRK09674  15 LTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNA-RFFAAGADLN-----EMAEKDLAATLNDPRPQLWQRL 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  129 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDV 207
Cdd:PRK09674  89 QAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKsLASQMVLTGESITAQQA 168
                        170       180       190
                 ....*....|....*....|....*....|.
gi 37594471  208 YRAGIATHFVDSE---KLAMLEEDLLALKSP 235
Cdd:PRK09674 169 QQAGLVSEVFPPEltlERALQLASKIARHSP 199
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
31-168 7.87e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 85.04  E-value: 7.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   31 HTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAK 110
Cdd:PRK06144   3 MTTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAE 82
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 37594471  111 QKIAPVFFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168
Cdd:PRK06144  83 DAVAYERRIDRVL--GALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
49-222 1.49e-18

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 84.36  E-value: 1.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   49 ITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFF---REEYMLN 125
Cdd:PRK03580  16 ITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFaglTEIFDLD 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  126 navgscqKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFR 201
Cdd:PRK03580  95 -------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPK---RLPPAIAnemvMTGRR 164
                        170       180
                 ....*....|....*....|.
gi 37594471  202 LKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK03580 165 MDAEEALRWGIVNRVVPQAEL 185
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
35-218 2.21e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 81.30  E-value: 2.21e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQ--- 111
Cdd:PRK07799   4 GPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG-AFCAGMDLKAATKKPPGDSfkd 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  112 -KIAPVffREEYMLNNAvgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpRLQGK 190
Cdd:PRK07799  83 gSYDPS--RIDALLKGR--RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAV--RLVRQ 155
                        170       180       190
                 ....*....|....*....|....*....|..
gi 37594471  191 LGYFLA----LTGFRLKGRDVYRAGIATHFVD 218
Cdd:PRK07799 156 IPYTVAcdllLTGRHITAAEAKEIGLIGHVVP 187
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
38-222 7.12e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 79.63  E-value: 7.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLN-MIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAkQKIAPV 116
Cdd:PRK09245   5 LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDMRARVGA-FGGSPA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  117 FFREEY-----MLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 190
Cdd:PRK09245  83 DIRQGYrhgiqRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGmA 162
                        170       180       190
                 ....*....|....*....|....*....|..
gi 37594471  191 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK09245 163 RAAEMAFTGDAIDAATALEWGLVSRVVPADQL 194
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
34-213 1.57e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 78.49  E-value: 1.57e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKakqki 113
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGG-TFCAGMDLKAFARGER----- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 apVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGY 193
Cdd:PRK08252  75 --PSIPGRGFGGLTERPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGG---LLRLPRRIPY 149
                        170       180
                 ....*....|....*....|....
gi 37594471  194 FLA----LTGFRLKGRDVYRAGIA 213
Cdd:PRK08252 150 HIAmelaLTGDMLTAERAHELGLV 173
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
35-275 3.39e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 77.73  E-value: 3.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEaekaKQKIA 114
Cdd:PRK07511   2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGG-FFCAGGNLNRLLE----NRAKP 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  115 PVFFREEY-MLNN---AVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR-LQG 189
Cdd:PRK07511  77 PSVQAASIdGLHDwirAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLPR 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  190 KLGYFLALTGFRLKGRDVYRAGIATHFVD-----SEKLAMLEEdlLALKSP-SKENIASVLENYHTESkidrdksfiLEE 263
Cdd:PRK07511 157 QLATELLLEGKPISAERLHALGVVNRLAEpgqalAEALALADQ--LAAGSPnALARIKSLIADAPEAT---------LAA 225
                        250
                 ....*....|..
gi 37594471  264 HMDKINSCFSAN 275
Cdd:PRK07511 226 QLEAERDHFVAS 237
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
32-242 4.12e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 77.38  E-value: 4.12e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   32 TDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDpETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQ 111
Cdd:PRK07659   2 TSKMESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAES-SAHIVVLRGNG-RGFSAGGDIKMMLSSNDESK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  112 KIAPVFFREEYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKL 191
Cdd:PRK07659  80 FDGVMNTISEIVV--TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK---RV 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 37594471  192 GYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA-LKSPSKENIAS 242
Cdd:PRK07659 155 GENKAkqiiWEGKKLSATEALDLGLIDEVIGGDFQTAAKQKISEwLQKPLKAMIET 210
PLN02600 PLN02600
enoyl-CoA hydratase
48-217 2.63e-15

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 74.84  E-value: 2.63e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV-----ISEAEKAKQKIAPVFfreey 122
Cdd:PLN02600   7 ELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKErrkmsPSEVQKFVNSLRSTF----- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  123 mlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFR 201
Cdd:PLN02600  82 ---SSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAKELIFTGRR 158
                        170
                 ....*....|....*.
gi 37594471  202 LKGRDVYRAGIATHFV 217
Cdd:PLN02600 159 IGAREAASMGLVNYCV 174
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
32-236 3.40e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 75.13  E-value: 3.40e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   32 TDAAEEVLLEKKGC-TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDI---RVISEAE 107
Cdd:PRK06210   1 DMAYDAVLYEVADSgVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGA-GRGFCAGADMgelQTIDPSD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  108 KAKQKIAPVFF---REEYMLNNA-VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 183
Cdd:PRK06210  80 GRRDTDVRPFVgnrRPDYQTRYHfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWI 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 37594471  184 LPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL--AMLE--EDLLALKSPS 236
Cdd:PRK06210 160 LPRLVGHANALdLLLSARTFYAEEALRLGLVNRVVPPDELmeRTLAyaEDLARNVSPA 217
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
49-189 3.49e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 75.43  E-value: 3.49e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIAPVFFREEYM----- 123
Cdd:PRK08260  17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLSAGGNTFDLDAPRTPVEADEEDRadpsd 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37594471  124 ---------LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK08260  96 dgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
36-207 3.65e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 75.01  E-value: 3.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIyPQLKKW-EQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIA 114
Cdd:PRK06142   6 ESFTVELADHVAQVTLNRPGKGNAMNPAFWSEL-PEIFRWlDADPEVRAVVLSGSG-KHFSYGIDLPAMAGVFGQLGKDG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  115 PVFFREEY------MLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 186
Cdd:PRK06142  84 LARPRTDLrreilrLQAaiNAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPR 163
                        170       180
                 ....*....|....*....|...
gi 37594471  187 LQGKlGYF--LALTgfrlkGRDV 207
Cdd:PRK06142 164 IIGD-GHLreLALT-----GRDI 180
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
38-235 1.20e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 73.38  E-value: 1.20e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRviSEAEKAKQKIAPVF 117
Cdd:PRK07509   5 VSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGG-AFCAGLDVK--SVASSPGNAVKLLF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  118 FREEYMLNNAvgscQK----------PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRL 187
Cdd:PRK07509  82 KRLPGNANLA----QRvslgwrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGL 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 37594471  188 QGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS---EKLAMLEEdlLALKSP 235
Cdd:PRK07509 158 VRKdVARELTYTARVFSAEEALELGLVTHVSDDplaAALALARE--IAQRSP 207
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
26-222 1.39e-14

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 72.96  E-value: 1.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    26 LRMSKHTDAAEEvllekkgctgvITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 105
Cdd:TIGR01929   4 IRYEKSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRGD 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   106 AEKAKQKIAPVFFREEymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP 185
Cdd:TIGR01929  73 YGYIDDSGVHRLNVLD--VQRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMA 150
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 37594471   186 RLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:TIGR01929 151 RIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
47-199 1.97e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 72.37  E-value: 1.97e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   47 GVITLN--RPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKqkiAPVFFREEYML 124
Cdd:PRK06143  16 GVATLTirNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQAS---AEAFISRLRDL 92
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 37594471  125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfPDVGGGYFLPRLQGKL-GYFLALTG 199
Cdd:PRK06143  93 CDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWArTRWLLLTG 167
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
47-223 3.22e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 72.01  E-value: 3.22e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   47 GV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIAPVFFREEYML 124
Cdd:PRK07468  14 GVatLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTADRATRIEEARRLAMM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:PRK07468  93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMSARLFDA 172
                        170
                 ....*....|....*....
gi 37594471  205 RDVYRAGIATHFVDSEKLA 223
Cdd:PRK07468 173 EEAVRLGLLSRVVPAERLD 191
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-218 3.61e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 74.10  E-value: 3.61e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471    41 EKKGCTGVITLNRPKF-LNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIsEAEKAKQKIAPVFFR 119
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMI-AACKTAQEVTQLSQE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   120 EEYMLNNAVGScQKPYVALIHGITMGGGVGLSVHGQFRVATE--KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LA 196
Cdd:TIGR02441  97 GQEMFERIEKS-QKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALdMM 175
                         170       180
                  ....*....|....*....|..
gi 37594471   197 LTGFRLKGRDVYRAGIATHFVD 218
Cdd:TIGR02441 176 LTGKKIRADRAKKMGIVDQLVD 197
PLN02888 PLN02888
enoyl-CoA hydratase
28-222 3.66e-14

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 71.71  E-value: 3.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   28 MSKHTDAAEEVLLEK-KGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEA 106
Cdd:PLN02888   1 TMTQTVSENLILVPKsRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGS-GRAFCSGVDLTAAEEV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  107 EKAKQKIA---PVFFREEymlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 183
Cdd:PLN02888  80 FKGDVKDVetdPVAQMER---------CRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQK 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 37594471  184 LPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PLN02888 151 LSRIIGaNRAREVSLTAMPLTAETAERWGLVNHVVEESEL 190
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
23-223 5.60e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 71.54  E-value: 5.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   23 LHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLnmirQIYPQLKKW----EQDPETFLIIIKGAGGkAFCAGG 98
Cdd:PRK08258   4 FRGSKRPLAGYEARHFLWEVDDGVATITLNRPERKNPLTF----ESYAELRDLfrelVYADDVKAVVLTGAGG-NFCSGG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   99 DIRVIseaekakqkIAPV----------FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168
Cdd:PRK08258  79 DVHEI---------IGPLtkmdmpellaFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFL 149
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 37594471  169 ETAIGLF-PDVGGGYFLPRL--QGKLGYFLaLTGFRLKGRDVYRAGIATHFVDSEKLA 223
Cdd:PRK08258 150 FTRVGLAgADMGACALLPRIigQGRASELL-YTGRSMSAEEGERWGFFNRLVEPEELL 206
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
36-230 6.53e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 70.92  E-value: 6.53e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKgAGGKAFCAGGDIRVISEAEKAKQ---- 111
Cdd:PRK07260   2 EHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLIN-ANGKVFSVGGDLVEMKRAVDEDDvqsl 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  112 -KIAPVFFREEYmlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG- 189
Cdd:PRK07260  81 vKIAELVNEISF----AIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGl 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 37594471  190 KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLL 230
Cdd:PRK07260 157 NRATHLAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLL 197
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
36-189 7.76e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 70.72  E-value: 7.76e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAP 115
Cdd:PRK09076   3 IELDLEIDGHVAILTLNNPP-ANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMA 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37594471  116 VFFREEY-MLNNAVGscqkPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK09076  82 RRFGEAFeALSAFRG----VSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVG 152
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
36-223 1.02e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 70.33  E-value: 1.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEqDPETFLIIIKGAgGKAFCAGGDI--RVISEAEKAKQKI 113
Cdd:PRK08140   4 ETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGA-GRGFCAGQDLadRDVTPGGAMPDLG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  114 APVffrEEYM--LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK- 190
Cdd:PRK08140  82 ESI---ETFYnpLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMa 158
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 37594471  191 --LGyfLALTGFRLKGRDVYRAGIATHFVDSEKLA 223
Cdd:PRK08140 159 raLG--LALLGEKLSAEQAEQWGLIWRVVDDAALA 191
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
38-217 2.19e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 69.28  E-value: 2.19e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLkkwEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKA-----KQK 112
Cdd:PRK08150   4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAF---ARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGegmhhSRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  113 IAPVFFREEYmlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpdVGGG--YFLPRLQGK 190
Cdd:PRK08150  81 WHRVFDKIQY--------GRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIF--VGGGgsVRVPRLIGV 150
                        170       180
                 ....*....|....*....|....*...
gi 37594471  191 LGYF-LALTGFRLKGRDVYRAGIATHFV 217
Cdd:PRK08150 151 ARMTdMMLTGRVYDAQEGERLGLAQYLV 178
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
28-175 4.81e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 68.43  E-value: 4.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   28 MSKHTDAAEEVLLEKKGCTGVI--TLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISe 105
Cdd:PRK08139   1 MMAPAAATEAPLLLREDRDGVAtlTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAA-GKAFCAGHDLKEMR- 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 37594471  106 AEKAKQKIAPVFFR-EEYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF 175
Cdd:PRK08139  79 AARGLAYFRALFARcSRVMQ--AIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLF 147
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
34-222 2.92e-12

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 66.30  E-value: 2.92e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDP-ETFLIIIKGAGgKAFCAG----------GDIRV 102
Cdd:PRK05981   2 QFKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAG-RGFCTGanlqgrgsggRESDS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  103 ISEAEKAKQKIAPVFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGY 182
Cdd:PRK05981  81 GGDAGAALETAYHPFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTW 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 37594471  183 FLPRLQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK05981 154 LLPRLVGKArAMELSLLGEKLPAETALQWGLVNRVVDDAEL 194
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
48-256 7.09e-12

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 65.09  E-value: 7.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNA 127
Cdd:PRK07827  18 TLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGG-TFCAGADLSEAGGGGGDPYDAAVARAREMTALLRA 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  128 VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG--YFlaLTGFRLKGR 205
Cdd:PRK07827  97 IVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAarYY--LTGEKFGAA 174
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 37594471  206 DVYRAGIATHFVDS--EKLAMLEEDlLALKSP-----SKE-NIASVLENYhteskiDRD 256
Cdd:PRK07827 175 EAARIGLVTAAADDvdAAVAALLAD-LRRGSPqglaeSKAlTTAAVLAGF------DRD 226
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
36-255 8.94e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 64.81  E-value: 8.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTG---VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIR----VISEAEK 108
Cdd:PRK06023   3 DHILVERPGAHPgvqVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEG-CFSAGNDMQdflaAAMGGTS 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  109 AKQKIAPvFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ 188
Cdd:PRK06023  82 FGSEILD-FLI-------ALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLM 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 37594471  189 GKLGYF--LALtGFRLKGRDVYRAGI-----ATHFVDSEKLAMLEEdlLALKSPSKENIASVLENYHTESKIDR 255
Cdd:PRK06023 154 GHQRAFalLAL-GEGFSAEAAQEAGLiwkivDEEAVEAETLKAAEE--LAAKPPQALQIARDLMRGPREDILAR 224
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
28-222 2.38e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 63.70  E-value: 2.38e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   28 MSKHTDAAEEVLLEK-KGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEA 106
Cdd:PRK05864   1 VAGYRSTMSLVLVDHpRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGA-GRGFSSGADHKSAGVV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  107 EKAKQKIAPVF-FREEYMLNNAVGSCQK---PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF-PDVGGG 181
Cdd:PRK05864  80 PHVEGLTRPTYaLRSMELLDDVILALRRlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLS 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 37594471  182 YFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK05864 160 YLLPRAIGSSRAFeIMLTGRDVDAEEAERIGLVSRQVPDEQL 201
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
47-249 5.98e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 62.35  E-value: 5.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK---AKQKIAPVFFReeym 123
Cdd:PRK11423  15 ATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVILRAPSGSKVWSAGHDIHELPSGGRdplSYDDPLRQILR---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  124 lnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYFLA----LTG 199
Cdd:PRK11423  91 ---MIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTNDAGFHIVkemfFTA 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 37594471  200 FRLKGRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIaSVLENYHT 249
Cdd:PRK11423 165 SPITAQRALAVGILNHVVEVEELEDFTLQMahhISEKAPlaiavIKEQL-RVLGEAHP 221
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
47-212 2.13e-10

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 62.22  E-value: 2.13e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   47 GVITLNRP-KFLNALTLNMIRQIYPQLKKWEQDPEtfliiIKG---AGGKA--FCAGGDIRVISEAEKAKQkiAPVFFRE 120
Cdd:PRK11154  17 AVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKE-----LKGvvfISGKPdnFIAGADINMLAACKTAQE--AEALARQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  121 EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT--EKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLAL 197
Cdd:PRK11154  90 GQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGvSTALDMIL 169
                        170
                 ....*....|....*
gi 37594471  198 TGFRLKGRDVYRAGI 212
Cdd:PRK11154 170 TGKQLRAKQALKLGL 184
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
27-243 4.65e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 60.06  E-value: 4.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   27 RMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE- 105
Cdd:PRK08272   1 IRPVDLDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGA-GKGFCAGYDLSAYAEg 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  106 --AEKAKQKIAPVFFREEY--------MLNNAVGS-----------CQKPYVALIHGITMGGGVGLSVHGQFRVATEkcl 164
Cdd:PRK08272  80 ssSGGGGGAYPGKRQAVNHlpddpwdpMIDYQMMSrfvrgfmslwhAHKPTVAKVHGYCVAGGTDIALHCDQVIAAD--- 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  165 fampETAIGLFPD-VGG----GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLalkspskEN 239
Cdd:PRK08272 157 ----DAKIGYPPTrVWGvpatGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLV-------ER 225

                 ....
gi 37594471  240 IASV 243
Cdd:PRK08272 226 IAAV 229
PLN02921 PLN02921
naphthoate synthase
32-189 5.37e-10

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 60.19  E-value: 5.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   32 TDAAEEVLLEKKGCTGV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKA 109
Cdd:PLN02921  61 GKEFTDIIYEKAVGEGIakITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKDGYV 140
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  110 KQKIAPvffREEYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpDVG-GGYFLPRL 187
Cdd:PLN02921 141 GPDDAG---RLNVLdLQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARL 216

                 ..
gi 37594471  188 QG 189
Cdd:PLN02921 217 VG 218
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
47-213 5.79e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 59.27  E-value: 5.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEqDPETFLIIIKGAGgKAFCAGGDIrviseaekAKQKIAPVFFREEYMLNN 126
Cdd:PRK07854  11 LTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQG-TVFCAGADL--------SGDVYADDFPDALIEMLH 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  127 AVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDvggGYFLPRLQGKLGYFLA----LTGFRL 202
Cdd:PRK07854  81 AIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSLVGGGRAramlLGAEKL 157
                        170
                 ....*....|.
gi 37594471  203 KGRDVYRAGIA 213
Cdd:PRK07854 158 TAEQALATGMA 168
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
36-147 6.00e-10

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 59.52  E-value: 6.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAP 115
Cdd:PRK07396  13 EDILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYGGYVDDDGVP 92
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 37594471  116 vffreeyMLN-----NAVGSCQKPYVALIHGITMGGG 147
Cdd:PRK07396  93 -------RLNvldlqRLIRTCPKPVIAMVAGYAIGGG 122
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
38-220 7.27e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 58.82  E-value: 7.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQKIAPVF 117
Cdd:PRK06563   1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAH-GEHFTAGLDLADVAPKLAAGGFPFPEG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  118 FREEYMLnnaVG-SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpRLQGKLGYFLA 196
Cdd:PRK06563  80 GIDPWGT---VGrRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILP-FGGATL--RFPQAAGWGNA 153
                        170       180
                 ....*....|....*....|....*...
gi 37594471  197 ----LTGFRLKGRDVYRAGIATHFVDSE 220
Cdd:PRK06563 154 mrylLTGDEFDAQEALRLGLVQEVVPPG 181
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
33-224 1.08e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 58.82  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   33 DAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviseAEKAKQK 112
Cdd:PRK08290   1 MEYEYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGA-GKHFSAGHDLG----SGTPGRD 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  113 IAPVFFREEYMLNNAVG-----------------------SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPE 169
Cdd:PRK08290  76 RDPGPDQHPTLWWDGATkpgveqryarewevylgmcrrwrDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPV 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 37594471  170 TAIGLfpdVGGGYFL------PRlqgKLGYFLaLTGFRLKGRDVYRAGIATHFV-----DSEKLAM 224
Cdd:PRK08290 156 VRMGI---PGVEYFAhpwelgPR---KAKELL-FTGDRLTADEAHRLGMVNRVVprdelEAETLEL 214
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
77-187 1.24e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 58.06  E-value: 1.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   77 QDPETFLIIIKgAGGKAFCAGGDIRVISEAEKAKQKIAPVffREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156
Cdd:PRK07938  42 ADPDTRVVVLR-AEGRGFNAGVDIKELQATPGFTALIDAN--RGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADV 118
                         90       100       110
                 ....*....|....*....|....*....|.
gi 37594471  157 RVATEKCLFAMPETAIGLfpdVGGGYFLPRL 187
Cdd:PRK07938 119 IVASDDATFGLPEVDRGA---LGAATHLQRL 146
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
51-235 2.42e-09

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 57.51  E-value: 2.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   51 LNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGS 130
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGR-GRHFSAGADLAWMQQSADLDYNTNLDDARELAELMYNLYR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  131 CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRA 210
Cdd:PRK05674 100 LKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRRAREL 179
                        170       180
                 ....*....|....*....|....*...
gi 37594471  211 G-IATHFVDSEKLAMLEE--DLLALKSP 235
Cdd:PRK05674 180 GlLAESYPAAELEAQVEAwiANLLLNSP 207
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
49-222 5.48e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 56.57  E-value: 5.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQKIAPVfFREEYMLNNAV 128
Cdd:PRK07327  25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDFEVRARV-WREARDLVYNV 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  129 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGlfpdVGGG----YFLPRLQG--KLGYFLaLTGFRL 202
Cdd:PRK07327 103 INCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLG----VAAGdhaaIVWPLLCGmaKAKYYL-LLCEPV 177
                        170       180
                 ....*....|....*....|
gi 37594471  203 KGRDVYRAGIATHFVDSEKL 222
Cdd:PRK07327 178 SGEEAERIGLVSLAVDDDEL 197
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
36-222 3.04e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 54.58  E-value: 3.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAG----------GDIRVISE 105
Cdd:PRK12478   5 QTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGydfgggfqhwGEAMMTDG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  106 AEKAKQKIAPVFFRE-----EYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAI-GLFPDvg 179
Cdd:PRK12478  84 RWDPGKDFAMVTAREtgptqKFM---AIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLT-- 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 37594471  180 gGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK12478 159 -GMWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERL 200
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
38-189 5.14e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 50.22  E-value: 5.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITL--NRPKfLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGaGGKAFCAGGDI---RVISEAEKAkqk 112
Cdd:PRK05869   8 VVSDGSQDAGLATLllSRPP-TNALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMpelRTLSAQEAD--- 82
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 37594471  113 IAPVFFREEYmlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK05869  83 TAARVRQQAV---DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
36-182 1.15e-06

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 49.43  E-value: 1.15e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG-----GKAFCAGGDIRVISeaekak 110
Cdd:COG0447  18 TDITYHRAEGIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGpskdgGWAFCSGGDQRVRG------ 91
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471 111 qkiapvffREEYMLNNAVG------------SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAmpETAiglfPDV 178
Cdd:COG0447  92 --------RGGYVYEDGVGrlnilevqrlirFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFG--QTG----PDV 157

                ....*..
gi 37594471 179 G---GGY 182
Cdd:COG0447 158 GsfdAGY 164
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
134-189 1.34e-06

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 50.25  E-value: 1.34e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 37594471  134 PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK11730 104 PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
38-217 1.44e-06

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 49.20  E-value: 1.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQKiapvf 117
Cdd:PRK07110   7 ELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGY-PNYFATGGTQEGLLSLQTGKGT----- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  118 FREEYMLNNAVGsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA- 196
Cdd:PRK07110  81 FTEANLYSLALN-CPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPE---KLGLALGq 156
                        170       180
                 ....*....|....*....|....
gi 37594471  197 ---LTGFRLKGRDVYRAGIATHFV 217
Cdd:PRK07110 157 emlLTARYYRGAELKKRGVPFPVL 180
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
36-189 1.96e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 48.74  E-value: 1.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAkqkiap 115
Cdd:PRK08259   3 MSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADLKAVGTGRGN------ 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  116 vffREEYMLNNAVGSCQ----KPYVALIHGITMGGGVGLSVHGQFRVATEKCLFampetaiGLF------PDVGGGYF-L 184
Cdd:PRK08259  76 ---RLHPSGDGPMGPSRmrlsKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVF-------GVFcrrwgvPLIDGGTVrL 145

                 ....*
gi 37594471  185 PRLQG 189
Cdd:PRK08259 146 PRLIG 150
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
29-222 2.97e-05

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 45.38  E-value: 2.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   29 SKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGgKAFCAGGDI-----RVI 103
Cdd:PRK09120   1 MSYENRWDTVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAG-DAWSAGMDLkeyfrETD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  104 SEAEKAKQKIApvffREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdvGGGY- 182
Cdd:PRK09120  80 AQPEILQERIR----REAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPP--GGGVs 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 37594471  183 -----FLPRLQgklGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK09120 154 kamadTVGHRD---ALYYIMTGETFTGRKAAEMGLVNESVPLAQL 195
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
38-241 1.18e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 43.13  E-value: 1.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471   38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETflIIIKGAGgKAFCAGGDIRVISEAEKAKQKIApvf 117
Cdd:PRK07112   6 IRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLP-EVFCFGADFSAIAEKPDAGRADL--- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37594471  118 FREE--YMLNNAVGScqKPYVALIH--GITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdvggGYFLPRLQGKLG- 192
Cdd:PRK07112  80 IDAEplYDLWHRLAT--GPYVTIAHvrGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP----ACVLPFLIRRIGt 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 37594471  193 ---YFLALTGFRLKGRDVYRAGIATHFV-DSEKLamLEEDLLALKSPSKENIA 241
Cdd:PRK07112 154 qkaHYMTLMTQPVTAQQAFSWGLVDAYGaNSDTL--LRKHLLRLRCLNKAAVA 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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