|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02906 |
PLN02906 |
xanthine dehydrogenase |
26-1321 |
0e+00 |
|
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain] Cd Length: 1319 Bit Score: 1711.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 26 ETTLLVYLRrKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTKK-LHPVQ 104
Cdd:PLN02906 1 HQTLLEYLR-DLGLTGTKLGCGEGGCGACTVMVSHYDRKTGKCVHYAVNACLAPLYSVEGMHVITVEGIGNRRDgLHPVQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 105 ERIAKSHGSQCGFCTPGIVMSMYTLLRNKPE-PTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNC-- 181
Cdd:PLN02906 80 EALASMHGSQCGFCTPGFIMSMYALLRSSKTpPTEEQIEECLAGNLCRCTGYRPILDAFRVFAKTDDALYTGVSSLSLqd 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 182 -------------CMSQTKDQTIAPSSSLFNPEDFKPLD----PTQEPIFPPELLRLKDTPRKTLRFEGerVTWIQVSTM 244
Cdd:PLN02906 160 gepicpstgkpcsCGSKTTSAAGTCKSDRFQPISYSEIDgswyTEKELIFPPELLLRKLTPLKLLGNGG--LTWYRPTSL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 245 EELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLSLVESVLADAIATLPEQ 324
Cdd:PLN02906 238 QHLLELKAEYPDAKLVVGNTEVGIEMRFKNAQYPVLISPTHVPELNAIKVKDDGLEIGAAVRLSELQNLFRKVVKERPAH 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 325 RTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASR-GTKRTVwMDHTFFPGYRRTLLSPE 403
Cdd:PLN02906 318 ETSACKAFIEQLKWFAGTQIRNVASIGGNICTASPISDLNPLWMAAGATFVIISCdGDIRSV-PASDFFLGYRKVDLKPD 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 404 EILVSIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTTE--VQELSLCFGGMADRTVSALKTTPKQLSKSWN 481
Cdd:PLN02906 397 EILLSVFLPWTRPFEYVKEFKQAHRRDDDIAIVNAGMRVKLEEKDGEwiVSDASIAYGGVAPLSVSARKTEEFLIGKPWN 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 482 EELLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLgRADLEGMCGkLDPTFASATLLFQKDPPANVQ 561
Cdd:PLN02906 477 KETLQDALKVLQKDILIKEDAPGGMVEFRKSLALSFFFKFFLWVSHQL-EADGSTIET-FPESHLSAAQPFPRPSSVGMQ 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 562 LFQEVPKGQSeedmVGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSE 641
Cdd:PLN02906 555 DYETVKQGTA----VGQPEVHLSAELQVTGEAEYADDIPMPPNTLHAALVLSTKPHARILSIDDSEAKSSPGFAGIFLAK 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 642 DVPGSNITG-IFNDETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFY-GPEVKIEK 719
Cdd:PLN02906 631 DVPGDNMIGpVVHDEELFATDVVTCVGQVIGVVVADTQENAKAAARKVKVEYEELPAILSIEEAIEAGSFHpNTERRLEK 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 720 GDLKKGFS--EADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRM 797
Cdd:PLN02906 711 GDVELCFAsgQCDRIIEGEVQMGGQEHFYLEPNSSLVWTSDSGNEVHMISSTQAPQKHQKYVAHVLGLPMSKVVCKTKRI 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 798 GGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLS 877
Cdd:PLN02906 791 GGGFGGKETRSAFIAAAAAVPAYLLNRPVKLTLDRDVDMMITGQRHAFLGKYKVGFTNEGKILALDLEIYNNGGNSLDLS 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 878 RSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTH 957
Cdd:PLN02906 871 GAVLERAMFHSDNVYEIPNVRIVGNVCFTNFPSNTAFRGFGGPQGMLITENWIQRIAVELNKSPEEIREMNFQGEGSVTH 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 958 FNQKLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHG 1037
Cdd:PLN02906 951 YGQVLQHCTLPQLWDELKVSCDFLKRREEVDEFNAKNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHG 1030
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1038 GTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKKKNPSGSWE 1117
Cdd:PLN02906 1031 GVEMGQGLHTKVAQVAASAFNIPLSSVFISETSTDKVPNASPTAASASSDMYGAAVLDACEQIKARMEPVASKLNFSSFA 1110
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1118 SWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQ 1197
Cdd:PLN02906 1111 ELVTACYFQRIDLSAHGFYITPDIGFDWKTGKGNPFNYFTYGAAFAEVEIDTLTGDFHTRRVDIVMDLGYSINPAIDIGQ 1190
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1198 VEGAFVQGLGLFTMEELHYS-------PEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLA 1270
Cdd:PLN02906 1191 IEGAFVQGLGWVALEELKWGdaahkwiRPGSLFTCGPGTYKIPSVNDIPFKFNVSLLKGAPNPKAIHSSKAVGEPPFFLA 1270
|
1290 1300 1310 1320 1330
....*....|....*....|....*....|....*....|....*....|.
gi 77682555 1271 SSIFFAIKDAIRAARAQHGDSNakqLFQLDSPATPEKIRNACVDQFTTLCA 1321
Cdd:PLN02906 1271 ASVFFAIKDAIKAARAEVGLHG---WFPLDTPATPERIRMACGDEITAPFA 1318
|
|
| mam_aldehyde_ox |
TIGR02969 |
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ... |
8-1335 |
0e+00 |
|
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain] Cd Length: 1330 Bit Score: 1507.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 8 ELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLTPICSLHHVA 87
Cdd:TIGR02969 2 ELLFYVNGRKVVEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPSTKSIRHHPVNACLTPICSLYGAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 88 VTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFA 166
Cdd:TIGR02969 82 VTTVEGIGSTRtRLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 167 KdggccggsgnNPNCCMSQTK-----DQTI----------APSSSLFNPEDFKPLDPTQEPIFPPELLRLKDT-PRKTLR 230
Cdd:TIGR02969 162 K----------TSGCCQSKENgvcclDQGInglpefeegdETSPELFSEEEFLPLDPTQELIFPPELMRMAEKqPQRTRV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 231 FEGERVTWIQVSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLSLV 310
Cdd:TIGR02969 232 FYSERMMWISPVTLKELLEAKFKYPQAPVVMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHTGDGLTLGAGLSLAQV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 311 ESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMDHT 390
Cdd:TIGR02969 312 KDILADVVQKLPEETTQTYRALLKHLGTLAGSQIRNMASLGGHIISRHLDSDLNPLLAVGNCTLNLLSKEGKRQIPLSEQ 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 391 FFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALK 470
Cdd:TIGR02969 392 FLSKCPDADLKPQEILVSVNIPYSRKWEFVSAFRQAQRQQNALAIVNSGMRVFFGEGDGIIRELSISYGGVGPTTICAKN 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 471 TTPKQLSKSWNEELLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADlEGMCGKLDPTFASATL 550
Cdd:TIGR02969 472 SCQKLIGRPWNEEMLDTACRLILDEVSLAGSAPGGKVEFKRTLIISFLFKFYLEVSQILKRMD-PGHYPSLADKYESALE 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 551 LFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKK 630
Cdd:TIGR02969 551 DLHSKHHWSTLKHQNVDSMQLPQDPIGHPIMHLSGVKHATGEAIYCDDMPAVDQELFLTFVTSSRAHAKIVSIDLSEALS 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 631 VPGFVCFLTSEDVPGSNITGIfndETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDL-PAIITIQDAIKNNS 709
Cdd:TIGR02969 631 LPGVVDIITAEHLQDANTFGT---EKLLATDKVHCVGQLVCAVIADSEVQAKQAAKHVKIVYRDLePLILTIEEAIQHKS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 710 FYGPEVKIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNR 789
Cdd:TIGR02969 708 FFEPERKLEYGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKYIQDIVAATLKLPVNK 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 790 IVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSN 869
Cdd:TIGR02969 788 VMCHVRRVGGAFGGKVGKTSIMAAITAFAANKHGRAVRCTLERGEDMLITGGRHPYLGKYKAGFMNDGRIVALDVEHYSN 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 870 GGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNM 949
Cdd:TIGR02969 868 GGSSLDESLWVIEMGLLKMDNAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAGLITEACITEVAAKCGLSPEKVRTINM 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 950 YKEGDLTHFNQKLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTD 1029
Cdd:TIGR02969 948 YKEIDQTPYKQEINAKNLFQCWRECMAKSSYSERKVAVEKFNAENYWKKRGLAVIPLKFPVGLGSVAMGQAAALVHIYLD 1027
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1030 GSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKK 1109
Cdd:TIGR02969 1028 GSVLVTHGGIEMGQGVHTKMIQVVSRELKMPMSNVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIIS 1107
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1110 KNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSL 1189
Cdd:TIGR02969 1108 KNPQGTWKDWAQTAFDQSISLSAVGYFRGYESNINWEKGEGHPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGHSI 1187
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1190 NPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFL 1269
Cdd:TIGR02969 1188 NPALDIGQVEGAFIQGMGLYTIEELSYSPQGILYSRGPNQYKIPAICDIPTELHISFLPPSEHSNTLYSSKGLGESGVFL 1267
|
1290 1300 1310 1320 1330 1340
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 77682555 1270 ASSIFFAIKDAIRAARAQHGDSNAkqlFQLDSPATPEKIRNACVDQFTTLCATGTPENCKSWSVRI 1335
Cdd:TIGR02969 1268 GCSVFFAIHDAVRAARQERGLSGP---WKLTSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNVPV 1330
|
|
| XdhB |
COG4631 |
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and ... |
576-1312 |
0e+00 |
|
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and metabolism];
Pssm-ID: 443669 [Multi-domain] Cd Length: 769 Bit Score: 1089.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 576 VGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSN-ITGIFND 654
Cdd:COG4631 14 VGKSLPHESARLHVTGEARYIDDLPEPAGTLHAAPGLSPVAHARILSIDLSAVRAAPGVVAVLTAADIPGENdIGPIIHD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 655 ETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLKKGFSEADNVVS 734
Cdd:COG4631 94 EPLLADGEVEYVGQPVFAVVAESREAARRAARLAKIEYEELPAILTIEEALAAGSFVLPPHTLRRGDADAALAAAPHRLE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 735 GELYIGGQEHFYLETHCTIAVPkGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTA 814
Cdd:COG4631 174 GEFEIGGQEHFYLEGQIALAIP-GEDGGMLVHSSTQHPSEVQHLVAHVLGVPMHAVTVEVRRMGGGFGGKESQAALFAAL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 815 VALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKI 894
Cdd:COG4631 253 AALAARKTGRPVKLRLDRDDDMVMTGKRHPFRIDYEVGFDDDGRILGLDITLAARCGWSADLSGPVADRAMFHADNAYYL 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 895 PNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMY--KEGDLTHFNQKLEGFTLPRCWD 972
Cdd:COG4631 333 PAVRITGHRCKTNTQSNTAFRGFGGPQGMLAIERVIDDIARALGLDPLDVRRRNFYgpAERNTTPYGQPVEDNILHELVD 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 973 ECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQV 1052
Cdd:COG4631 413 ELEESSDYAARRAAIAAFNAASPVLKRGLALTPVKFGISFTATHLNQAGALVHVYTDGSVQLNHGGTEMGQGLHTKVAQV 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1053 ASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPF-------------------KKKNPS 1113
Cdd:COG4631 493 VADELGVPLERVRITATDTDKVPNTSATAASSGSDLNGMAAQDACRQIRERLAAFaaellgvepedvrfadgrvRVGGQS 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1114 GSWESWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAI 1193
Cdd:COG4631 573 LSFAELVKAAYLARVSLSATGFYKTPKIHWDRATGQGRPFYYFAYGAAVSEVEIDTLTGEYRVLRVDILHDVGRSLNPAI 652
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1194 DIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSI 1273
Cdd:COG4631 653 DIGQIEGGFVQGMGWLTTEELVWDDKGRLLTHAPSTYKIPAASDRPEDFNVALLERPNREDTIYRSKAVGEPPLMLGISV 732
|
730 740 750
....*....|....*....|....*....|....*....
gi 77682555 1274 FFAIKDAIrAARAQHGDSnakqlFQLDSPATPEKIRNAC 1312
Cdd:COG4631 733 FEALRDAV-AAVGDYRVS-----PPLDAPATPERVLMAV 765
|
|
| xanthine_xdhB |
TIGR02965 |
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the ... |
576-1312 |
0e+00 |
|
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the molybdopterin-containing large subunit (or, in, eukaryotes, the molybdopterin-binding domain) of xanthine dehydrogenase, and enzyme that reduces the purine pool by catabolizing xanthine to urate. This model is based primarily on bacterial sequences; it does not manage to include all eukaryotic xanthine dehydrogenases and thereby discriminate them from the closely related enzyme aldehyde dehydrogenase. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274367 [Multi-domain] Cd Length: 758 Bit Score: 896.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 576 VGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSN-ITGIFND 654
Cdd:TIGR02965 1 VGTSLKHESAHKHVAGTAVYIDDIPEPAGTLHAALGLSTRAHARITSMDLSAVRAAPGVVDVLTAADIPGENdISPIIHD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 655 ETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAI-KNNSFYGPEVKIEKGDLKKGFSEADNVV 733
Cdd:TIGR02965 81 DPLLADGKVEFVGQPIFAVVATSRDAARRAARLAKIEYEELPAVLDIEEALaAGSRLVTPPLTLERGDAAAALAAAPHRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 734 SGELYIGGQEHFYLETHCTIAVPkGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLIST 813
Cdd:TIGR02965 161 SGTMRIGGQEHFYLEGQIALAVP-GEDGGMHVWSSTQHPSEVQHLVAHVLGVPSHAVTVEVRRMGGGFGGKETQANLFAC 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 814 AVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYK 893
Cdd:TIGR02965 240 LAAVAARKTGRPVKLRPDRDDDMMITGKRHDFRVDYDVGFDDEGRILGVDIDMAARCGFSADLSGPVTDRALFHADNAYF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 894 IPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGD--LTHFNQKLEGFTLPRCW 971
Cdd:TIGR02965 320 LPDVTITSHPLKTNTQSNTAFRGFGGPQGMVAIERIMDEVARALGKDPLEVRKRNFYGKDErnVTPYHQTVEDNIIHEII 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 972 DECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQ 1051
Cdd:TIGR02965 400 EELEASSDYAARRAAIRAFNATSPVLKKGIALTPVKFGISFTVTHLNQAGALVHVYTDGSIHLNHGGTEMGQGLNTKVAQ 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1052 VASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKKKNPSG----------------- 1114
Cdd:TIGR02965 480 VVAEEFQVDIDRVKITATDTGKVPNTSATAASSGSDLNGMAAQDAARQIKERLVEFAAEKWQVpeedvrfapnhvrvgeq 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1115 --SWESWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPA 1192
Cdd:TIGR02965 560 rvPFAELVQQAYFARVQLSSTGFYKTPKIHWDRAKGRGRPFYYFAYGAACSEVSVDTLTGEYKVLRADILHDVGRSLNPA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1193 IDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRA-IYASKAVGEPPLFLAS 1271
Cdd:TIGR02965 640 IDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPAASDRPKDFNVRLFEWGENREDtIHRSKAVGEPPLMLGI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|.
gi 77682555 1272 SIFFAIKDAIRAAraqhGDSNAKQlfQLDSPATPEKIRNAC 1312
Cdd:TIGR02965 720 SVLFAISDAVASV----ADYRVCP--RLDAPATPERVLMAV 754
|
|
| PLN00192 |
PLN00192 |
aldehyde oxidase |
4-1312 |
0e+00 |
|
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain] Cd Length: 1344 Bit Score: 781.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 4 TTVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLTPICSL 83
Cdd:PLN00192 1 SSNMSLVFAVNGERFELSSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLLSKYDPVLDQVEDFTVSSCLTLLCSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 84 HHVAVTTVEGIGNTKK-LHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRN-----KPEP-------TVEEIENAFQGNLC 150
Cdd:PLN00192 81 NGCSITTSEGLGNSKDgFHPIHKRFAGFHASQCGFCTPGMCISLFSALVNadktdRPEPpsgfsklTVVEAEKAVSGNLC 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 151 RCTGYRPILQGFRTFAKDGGCCGGSGnnpNCCMSQTKDQTiAPSSSLfnpedfKPLDPTQEPIFPPELLrlKDTPRKTLR 230
Cdd:PLN00192 161 RCTGYRPIVDACKSFAADVDIEDLGL---NSFWKKGESEE-AKLSKL------PPYNHSDHICTFPEFL--KKEIKSSLL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 231 FEGERVTWIQVSTMEELLDL-KAQHPDA---KLVVGNTEIGIemkFKNM-LFPLIICPAWILELTSVAHGPEGISFGAAC 305
Cdd:PLN00192 229 LDSSRYRWYTPVSVEELQSLlESNNFDGvsvKLVVGNTGTGY---YKDEeLYDKYIDIRHIPELSMIRRDEKGIEIGAVV 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 306 PLSlvesvlaDAIATLPEQRTE--VFRGVMEQLRWFAGKQVKSVASIGGNIITAS----PiSDLNPVLMASRAKLTLASR 379
Cdd:PLN00192 306 TIS-------KAIEALREESKSeyVFKKIADHMEKIASRFVRNTGSIGGNLVMAQrkqfP-SDIATILLAAGSTVNIQNA 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 380 GTKRTVWMDHtFFpgyRRTLLSPEEILVSIVIPYSRKGE------FFSAFKQASR-REDDIAKVTSGMRVLFK----PGT 448
Cdd:PLN00192 378 SKREKLTLEE-FL---ERPPLDSKSLLLSVEIPSWTSSSgsdtklLFETYRAAPRpLGNALPYLNAAFLAEVSqdasSGG 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 449 TEVQELSLCFGGM-ADRTVSALKT----TPKQLSKSWNEE---LLQDVcaglaeelhLAPDAPGGMVEFRRTLTLSFFFK 520
Cdd:PLN00192 454 IVVNDCRLAFGAYgTKHAIRARKVeeflTGKVLSDSVLYEavrLLKGI---------VVPEDGTSHPEYRSSLAVGFLFD 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 521 FYLTVLQ---KLGRADLEGMCGKLDPTFASATLLFQKDPPANVQLFQEvpkgQSEEDMVGRPMPHLAADMQASGEAVYCD 597
Cdd:PLN00192 525 FLSPLIEsnaKSSNGWLDGGSNTKQNPDQHDDVKKPTLLLSSKQQVEE----NNEYHPVGEPIKKVGAALQASGEAVYVD 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 598 DIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVP--GSNI--TGIFNDETVFAkDEVT-CVGHIIGA 672
Cdd:PLN00192 601 DIPSPKNCLYGAFIYSTKPLARVKGIKFKSNLVPQGVLAVITFKDIPkgGQNIgsKTIFGPEPLFA-DEVTrCAGQRIAL 679
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 673 VVADTPEHAHRAARGVKITY--EDL-PAIITIQDAIKNNSFYG--PEVKIEK-GDLKKGFSEADN-VVSGELYIGGQEHF 745
Cdd:PLN00192 680 VVADTQKHADMAANLAVVEYdtENLePPILTVEDAVKRSSLFEvpPFLYPKPvGDISKGMAEADHkILSAEIKLGSQYYF 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 746 YLETHCTIAVPKgEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRP 825
Cdd:PLN00192 760 YMETQTALALPD-EDNCIVVYSSTQCPEYVHSVIARCLGIPEHNVRVITRRVGGGFGGKAVKSMPVATACALAAFKLQRP 838
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 826 VRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSrSIMERAVFHMDNAYKIPNIRGTGRICK 905
Cdd:PLN00192 839 VRMYLNRKTDMIMAGGRHPMKITYSVGFKSDGKITALHLDILINAGISPDIS-PIMPRNIIGALKKYDWGALSFDIKVCK 917
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 906 TNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLEG----FTLPRCWDECIASSQYQ 981
Cdd:PLN00192 918 TNLSSRSAMRAPGEVQGSYIAEAIIEHVASTLSMDVDSVRKINLHTYESLKLFYGDSAGepseYTLPSIWDKLASSSEFK 997
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 982 ARKMEVEKFNRENCWKKRGLCIIPTKFGISftlsfLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRAL---K 1058
Cdd:PLN00192 998 QRTEMVKEFNRSNKWKKRGISRVPIVHEVM-----LRPTPGKVSILSDGSIAVEVGGIEIGQGLWTKVKQMAAFGLgmiK 1072
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1059 IPTS-----KIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKK----KNPSGSWESWVMDAYTSAVS 1129
Cdd:PLN00192 1073 CDGGedlldKIRVIQSDTLSMIQGGFTAGSTTSESSCEAVRLCCVILVERLKPIKErlqeQMGSVTWDMLISQAYMQSVN 1152
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1130 LSATGFYkTPNLgysfetnsgNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLF 1209
Cdd:PLN00192 1153 LSASSYY-TPDP---------SSMEYLNYGAAVSEVEVDLLTGETTILRSDIIYDCGQSLNPAVDLGQIEGAFVQGIGFF 1222
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1210 TMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQ-- 1287
Cdd:PLN00192 1223 MLEEYTTNSDGLVVTDGTWTYKIPTVDTIPKQFNVEILNSGHHKKRVLSSKASGEPPLLLAASVHCATRAAIREARKQll 1302
|
1370 1380
....*....|....*....|....*..
gi 77682555 1288 --HGDSNAKQLFQLDSPATPEKIRNAC 1312
Cdd:PLN00192 1303 swGGIDGSDSTFQLPVPATMPVVKELC 1329
|
|
| xanthine_xdhA |
TIGR02963 |
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ... |
9-525 |
2.25e-170 |
|
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274365 [Multi-domain] Cd Length: 467 Bit Score: 515.29 E-value: 2.25e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 9 LVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQnKIVHFSVNACLTPICSLHHVAV 88
Cdd:TIGR02963 1 IRFFLNGETVTLSDVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVGELVDGG-KLRYRSVNACIQFLPSLDGKAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 89 TTVEGIGNTKK-LHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGfrtfak 167
Cdd:TIGR02963 80 VTVEDLRQPDGrLHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILDA------ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 168 dggccggsgnnpnccMSQTKDQTIAPssslfnpedfkPLDPTQEPIFpPELLRLKDTPRKTLRFEGERVtwIQVSTMEEL 247
Cdd:TIGR02963 154 ---------------AEAAFDYPCSD-----------PLDADRAPII-ERLRALRAGETVELNFGGERF--IAPTTLDDL 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 248 LDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLSLVESVLADAIATLPeqrte 327
Cdd:TIGR02963 205 AALKAAHPDARIVAGSTDVGLWVTKQMRDLPDVIYVGQVAELKRIEETDDGIEIGAAVTLTDAYAALAKRYPELG----- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 328 vfrgvmEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMDhTFFPGYRRTLLSPEEILV 407
Cdd:TIGR02963 280 ------ELLRRFASLQIRNAGTLGGNIANGSPIGDSPPALIALGARLTLRKGEGRRTLPLE-DFFIDYGKTDRQPGEFVE 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 408 SIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTteVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQD 487
Cdd:TIGR02963 353 ALHVPRPTPGERFRAYKISKRFDDDISAVCAAFNLELDGGV--VAEIRIAFGGMAATPKRAAATEAALLGKPWNEATVEA 430
|
490 500 510
....*....|....*....|....*....|....*....
gi 77682555 488 VCAGLAEELH-LAPDAPGGmvEFRRTLTLSFFFKFYLTV 525
Cdd:TIGR02963 431 AMAALAGDFTpLSDMRASA--EYRLLTAKNLLRRFFLET 467
|
|
| CoxL |
COG1529 |
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ... |
576-1311 |
1.74e-162 |
|
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain] Cd Length: 741 Bit Score: 504.77 E-value: 1.74e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 576 VGRPMPHLAADMQASGEAVYCDDIpRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNIT--GIFN 653
Cdd:COG1529 10 IGKPVPRVDGPAKVTGRARYTDDI-RLPGMLYAAVVRSPHAHARIKSIDTSAALALPGVVAVLTGEDLPGLKFGlpGPDP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 654 DETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIK-----------NNSFYgpEVKIEKGDL 722
Cdd:COG1529 89 DQPPLADDKVRYVGEPVAAVVAETREAARDAAELIKVEYEPLPAVVDPEAALApgaplvheelpGNVAA--EWRGERGDV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 723 KKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEaGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFG 802
Cdd:COG1529 167 DAAFAEADVVVEATYTTPRLAHAPMEPRAAVAEWDGD-GRLTVWASTQGPHLVRRALARALGLPPEKVRVIAPDVGGGFG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 803 GKETrSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIME 882
Cdd:COG1529 246 GKLD-VYPEEVLAALAARKLGRPVKLVLTREEDFLADTHRHATVQRVRLGADKDGKITALRHDVVADTGAYASFGEAVLP 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 883 RAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKL 962
Cdd:COG1529 325 LGATMATGPYAIPNVRVEARAVYTNTPPTGAYRGPGRPQAAFALESAMDELAEELGMDPVELRLRNLIRPGDFPPTGQPY 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 963 EGFTLPRCWDECIASSQYQARKMEVEKFnRENCWKKRGLCIiptkfGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMG 1042
Cdd:COG1529 405 DSGRLAECLEKAAEAFGWGERRARPAEA-RAGKLRGIGVAA-----YIEGSGGGGDPESARVRLNPDGSVTVYTGATDIG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1043 QGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRL------------------ 1104
Cdd:COG1529 479 QGHETVLAQIAAEELGVPPEDVRVVLGDTDLTPYGGGTGGSRSTAVGGSAVRKAAEKLREKLlelaahllgadpedlefe 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1105 -EPFKKKNPSGSWESWVMDAYtsAVSLSATGFYKTPnlgysfetnsgnPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVM 1183
Cdd:COG1529 559 dGRVRVPGRSVSLAELAAAAY--YGGLEATGTYDPP------------TYPTYSFGAHVAEVEVDPETGEVRVLRVVAVH 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1184 DVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPiEFRVSLLrDCPNKRAIYASKAVG 1263
Cdd:COG1529 625 DCGRVINPLLVEGQVEGGVVQGIGQALYEELVYDEDGQLLNANFADYLVPRAADVP-EIEVIFV-ETPDPTNPLGAKGVG 702
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 77682555 1264 EPPLFLASSiffAIKDAIRAA---RaqhgdsnakqlfQLDSPATPEKIRNA 1311
Cdd:COG1529 703 EPGTIGVAP---AIANAVYDAtgvR------------IRDLPITPEKVLAA 738
|
|
| MoCoBD_1 |
pfam02738 |
Molybdopterin cofactor-binding domain; |
718-949 |
2.30e-118 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain] Cd Length: 244 Bit Score: 368.71 E-value: 2.30e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 718 EKGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRM 797
Cdd:pfam02738 14 EKGDVEAAFAEADHVVEGEYRTGRQEHFYMETRAALAVPDDEDGRLTVYSSTQGPHLVRRLVARVLGIPENKVRVIVPRV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 798 GGGFGGKeTRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLS 877
Cdd:pfam02738 94 GGGFGGK-TQSYPEEALAALAARKTGRPVKWVLDREEDMLATGHRHPFLIKYKVGADKDGKILALDVDLYADGGAYADLS 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77682555 878 RSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNM 949
Cdd:pfam02738 173 PAVPERALSHLDGPYKIPNVRVDGRAVYTNTPPNGAFRGFGRPQGMFALERLMDELAEELGMDPLELRRRNL 244
|
|
| MoCoBD_2 |
pfam20256 |
Molybdopterin cofactor-binding domain; |
973-1239 |
6.44e-118 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain] Cd Length: 282 Bit Score: 369.17 E-value: 6.44e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 973 ECIASSQYQARKMEVEKFNRENcwKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQV 1052
Cdd:pfam20256 1 KALELSDYDERRAEQAEFNRGN--RKRGIGIAPYVEGSGLGPGALNQAGALVRLNPDGSVTVYTGGTEMGQGLETKLAQI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1053 ASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPF---------------------KKKN 1111
Cdd:pfam20256 79 AAEALGIPPEDVRVVEGDTDTVPNGGGTGASRSTDVGGNAVLLAAEKLRERLLKIaahlleaspedlefedgkvyvKGDP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1112 PSGSWESWVMDAYTSAVSLSATGFYKTPNlgysFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNP 1191
Cdd:pfam20256 159 RSVTFAELAAAAYGEGVGLSATGFYTPPD----DETGQGPPFAYYPYGAHAAEVEVDPETGEVRVLRYVAVHDCGRVINP 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 77682555 1192 AIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIP 1239
Cdd:pfam20256 235 AIVEGQIEGGFVQGIGLALMEELVYDEDGQLLTASLMDYKIPTAADIP 282
|
|
| XdhA |
COG4630 |
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ... |
11-495 |
5.72e-110 |
|
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];
Pssm-ID: 443668 [Multi-domain] Cd Length: 476 Bit Score: 355.21 E-value: 5.72e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 11 FFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKlgcgeggcgacTVMISkydRLQNKIVHF-SVNACLTPICSLHHVAVT 89
Cdd:COG4630 3 FLLNGELVELSDVPPTTTLLDWLREDRGLTGTKegcaegdcgacTVVVG---ELDDGGLRYrAVNACILFLPQLDGKALV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 90 TVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQgfrtfakd 168
Cdd:COG4630 80 TVEGLAGPDgALHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIID-------- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 169 ggccggsgnnpnccmsqtkdqtiAPSSSLFNPEDfKPLDPTQEPIfPPELLRLKDTPRKTLRFEGERvtWIQVSTMEELL 248
Cdd:COG4630 152 -----------------------AARAMAEAPAP-DPFAADRAAV-AAALRALADGETVELGAGGSR--FLAPATLDELA 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 249 DLKAQHPDAKLVVGNTEIGIEMKfKNM-LFPLIICPAWILELTSVAHGPEGISFGAACPLSLVESVLADAIATLPEqrte 327
Cdd:COG4630 205 ALLAAHPDARLVAGATDVGLWVT-KQLrDLPPVIFLGRVAELRRIEETDDGLEIGAAVTLSDAEAALAAHFPELAE---- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 328 vfrgvMeqLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMDHtFFPGYRRTLLSPEEILV 407
Cdd:COG4630 280 -----L--LRRFASRQIRNAGTLGGNIANGSPIGDSPPALIALGAELVLRSGDGRRTLPLED-FFLGYRKTDLQPGEFVE 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 408 SIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTteVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQD 487
Cdd:COG4630 352 AIRIPLPAAGQRLRAYKVSKRFDDDISAVCAAFALTLDDGT--VTEARIAFGGMAATPKRARAAEAALLGQPWTEATVAA 429
|
....*...
gi 77682555 488 VCAGLAEE 495
Cdd:COG4630 430 AAAALAQD 437
|
|
| PRK09970 |
PRK09970 |
xanthine dehydrogenase subunit XdhA; Provisional |
574-1284 |
1.40e-79 |
|
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain] Cd Length: 759 Bit Score: 279.27 E-value: 1.40e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 574 DMVGRPMPHLAADMQASGEAVYCDDIPRyENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPgsNITgiFN 653
Cdd:PRK09970 1 MAIGKSIMRVDAIAKVTGRAKYTDDYVM-AGMLYAKYVRSPIAHGKVKSIDTEEARSLPGVEAVFTWEDVP--DIP--FP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 654 --------DET-------VFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSfygPEV--- 715
Cdd:PRK09970 76 taghpwslDPNhrdiadrALLTRHVRHHGDAVAAVVARDELTAEKALKLIKVEYEELPVITDPEAALAEGA---PPIhng 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 716 --------KIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVpKGEAGEMELFVSTQNTMKTQSFIAKMLGVPD 787
Cdd:PRK09970 153 rgnllkqsTMSTGNVQQTIKAADYQVQGHYETPIVQHCHMENVTSYAY-MEDDGRITIVSSTQIPHIVRRVVGQALGIPW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 788 NRIVVRVKRMGGGFGGK-----ETRSTLISTAVAlaayktGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVAL 862
Cdd:PRK09970 232 GKVRVIKPYVGGGFGNKqdvleEPLAAFLTSKVG------GRPVKVSLSREECFLATRTRHAFTIDIKMGVNRDGTLKGY 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 863 EVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAE 942
Cdd:PRK09970 306 SLDVLSNTGAYASHGHSIASAGGNKVAYLYPRCAYKYSSKTVYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPV 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 943 EVRRKNMYKEGDLTHFNQK-LEGFTLPRCWDECIASSQYQARKmevEKFNRENCWKKRGL-CIIPTKFGISFTLSfLNQG 1020
Cdd:PRK09970 386 EFRLRNAAREGDANPLSGKrIYSAGLPECLEKGRKIFEWDKRR---AECKNQQGNLRRGVgVACFSYTSGTWPVG-LEIA 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1021 GALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIH-ITETSTNTVPNTSPTAASASADLNGQAIYEAC-- 1097
Cdd:PRK09970 462 GARLLMNQDGTVQVQSGATEIGQGSDTVFSQMVAETVGIPVSDVRvISTQDTDVTPFDPGAYASRQSYVAGPAIRKAAle 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1098 --QTILK------RLEPFK---------KKNPSG---SWESWVMDAYTSavslSATGFYKTPNLGYSFETNSgnpfhyFS 1157
Cdd:PRK09970 542 lkEKILAhaavmlHQSAMNldiidghivVKRPGEplmSLEELAMDAYYH----PERGGQITAESSIKTTTNP------PA 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1158 YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPE-GS------LHTRGPSTY 1230
Cdd:PRK09970 612 FGCTFVDVEVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDEKtGVvrnpnlLDYKLPTMM 691
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....
gi 77682555 1231 KIPAFGSIPIEfrvsllrdCPNKRAIYASKAVGEPPlflASSIFFAIKDAIRAA 1284
Cdd:PRK09970 692 DLPQLESAFVE--------IYEPQSAYGHKSLGEPP---IISPAPAIRNAVLMA 734
|
|
| FAD_binding_5 |
pfam00941 |
FAD binding domain in molybdopterin dehydrogenase; |
235-414 |
2.51e-55 |
|
FAD binding domain in molybdopterin dehydrogenase;
Pssm-ID: 460007 [Multi-domain] Cd Length: 170 Bit Score: 189.68 E-value: 2.51e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 235 RVTWIQVSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLS-LVESV 313
Cdd:pfam00941 2 KFGYYRPASLAEALELLAAGPDAKLVAGGTSLGPLMKLRLARPDHLIDINGIPELRGIEETDGGLEIGAAVTLSeIAEPL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 314 LADAIATLPeqrtevfrgvmEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMDHtFFP 393
Cdd:pfam00941 82 LREAYPALS-----------EALRKIASPQIRNVGTIGGNIANASPISDLPPALLALDAKVELRSGEGERTVPLED-FFL 149
|
170 180
....*....|....*....|.
gi 77682555 394 GYRRTLLSPEEILVSIVIPYS 414
Cdd:pfam00941 150 GYGKTALEPGELITAVIIPLP 170
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
554-1311 |
1.68e-54 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 207.38 E-value: 1.68e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 554 KDPPANVQLfqeVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDD-IPryENELSLRLVTSTRAHAKIMSIDTSEAKKVP 632
Cdd:PRK09800 153 NNPQATIDI---APTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDrVT--ADACVIKMLRSPHAHALITHLDVSKAEALP 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 633 GFVCFLTSEDVPgsNITGIFN----------DETVFAKdEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQ 702
Cdd:PRK09800 228 GVVHVITHLNCP--DIYYTPGgqsapepsplDRRMFGK-KMRHVGDRVAAVVAESEEIALEALKLIDVEYEVLKPVMSID 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 703 DAIKNNS----------FYGPEVKIEK----------------------------------GDLKKGFSEADNVVSGELY 738
Cdd:PRK09800 305 EAMAEDApvvhdepvvyVAGAPDTLEDdnshaaqrgehmiinfpigsrprkniaasihghiGDMDKGFADADVIIERTYN 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 739 IGGQEHFYLETHCTIAVPKGEagEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKEtrSTLISTAVALA 818
Cdd:PRK09800 385 STQAQQCPTETHICFTRMDGD--RLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQ--DILLEEVCAWA 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 819 AYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIR 898
Cdd:PRK09800 461 TCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGNHSLTVPCNGPALSLPLYPCDNVD 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 899 GTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGD----LTHFNQKLEGFTLPRCWDEC 974
Cdd:PRK09800 541 FQVTTYYSNICPNGAYQGYGAPKGNFAITMALAELAEQLQIDQLEIIERNRVHEGQelkiLGAIGEGKAPTSVPSAASCA 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 975 IASSQYQARKM-EVEKFNRENC-WK-KRGLCIIPTKFGIsftlSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQ 1051
Cdd:PRK09800 621 LEEILRQGREMiQWSSPKPQNGdWHiGRGVAIIMQKSGI----PDIDQANCMIKLESDGTFIVHSGGADIGTGLDTVVTK 696
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1052 VASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRL---------EPF-------------KK 1109
Cdd:PRK09800 697 LAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARLAAENLREKIlfhgaqmlgEPVadvqlatpgvvrgKK 776
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1110 KNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGysfetnsgnpfhyFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSL 1189
Cdd:PRK09800 777 GEVSFGDIAHKGETGTGFGSLVGTGSYITPDFA-------------FPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPV 843
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 1190 NPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLrdcPNKRAI--YASKAVGEPPL 1267
Cdd:PRK09800 844 NPELALGQIYGATLRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLV---PSDDKVgpFGAKSISEIGV 920
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 77682555 1268 FLAS-SIFFAIKDAIraaraqhgdsnakQLFQLDSPATPEKIRNA 1311
Cdd:PRK09800 921 NGAApAIATAIHDAC-------------GIWLREWHFTPEKILTA 952
|
|
| Ald_Xan_dh_C |
pfam01315 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; |
590-696 |
1.80e-43 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain] Cd Length: 107 Bit Score: 153.54 E-value: 1.80e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 590 SGEAVYCDDIPRYENELsLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNIT-GIFNDETVFAKDEVTCVGH 668
Cdd:pfam01315 1 TGEAVYVDDIPAPGNLY-GAFVRSTIAHAKIVSIDTSAALALPGVVAVITAKDLPGGNYNiGPIPLDPLFATDKVRHVGQ 79
|
90 100
....*....|....*....|....*...
gi 77682555 669 IIGAVVADTPEHAHRAARGVKITYEDLP 696
Cdd:pfam01315 80 PIAAVVADDEETARRAAKLVKVEYEELP 107
|
|
| Ald_Xan_dh_C |
smart01008 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ... |
590-696 |
9.08e-42 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain] Cd Length: 107 Bit Score: 148.44 E-value: 9.08e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 590 SGEAVYCDDIpRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFN-DETVFAKDEVTCVGH 668
Cdd:smart01008 1 TGEARYGDDI-RLPGMLHAAVVRSPVAHARIKSIDTSAARAMPGVVAVLTAKDVPGLNDFGPLGpDEPVLADDKVRYVGQ 79
|
90 100
....*....|....*....|....*...
gi 77682555 669 IIGAVVADTPEHAHRAARGVKITYEDLP 696
Cdd:smart01008 80 PVAAVVAETEEAARDAAEAVKVEYEELP 107
|
|
| CutS |
COG2080 |
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ... |
11-167 |
3.26e-41 |
|
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441683 [Multi-domain] Cd Length: 155 Bit Score: 148.70 E-value: 3.26e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 11 FFVNGKKVvEKNADPETTLLVYLRRKLGLCGTKlgcgeggcgactvmiskydrlqnK----------IVHF---SVNACL 77
Cdd:COG2080 6 LTVNGKPV-EVDVDPDTPLLDVLRDDLGLTGTK-----------------------FgcghgqcgacTVLVdgkAVRSCL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 78 TPICSLHHVAVTTVEGIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRP 157
Cdd:COG2080 62 TLAVQADGKEITTIEGLAEDGELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVR 141
|
170
....*....|
gi 77682555 158 ILQGFRTFAK 167
Cdd:COG2080 142 IVRAVKRAAA 151
|
|
| Fer2_2 |
pfam01799 |
[2Fe-2S] binding domain; |
90-160 |
1.49e-34 |
|
[2Fe-2S] binding domain;
Pssm-ID: 460336 [Multi-domain] Cd Length: 73 Bit Score: 126.78 E-value: 1.49e-34
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77682555 90 TVEGIGNTKKlHPVQERIAKSHGSQCGFCTPGIVMSMYTLL-RNKPEPTVEEIENAFQGNLCRCTGYRPILQ 160
Cdd:pfam01799 1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLeRNPPPPTEAEIREALSGNLCRCTGYRRIVD 71
|
|
| CutB |
COG1319 |
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion] ... |
237-513 |
6.57e-33 |
|
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 440930 [Multi-domain] Cd Length: 285 Bit Score: 129.47 E-value: 6.57e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 237 TWIQVSTMEELLDLKAQH-PDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLSlvesvla 315
Cdd:COG1319 5 EYHRPTSLEEALALLAEHgPDARVLAGGTDLLPLMKLRLARPEHLVDINRIPELRGIEEEGGGLRIGALVTHA------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 316 dAIATLPEQRtEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMDHtFFPGY 395
Cdd:COG1319 78 -ELAASPLVR-ERYPLLAEAARAIASPQIRNRGTIGGNLANADPAADLPPALLALDATVELAGPDGERTIPAAD-FFLGP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 396 RRTLLSPEEILVSIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTteVQELSLCFGGMADRTVSALKTTPKQ 475
Cdd:COG1319 155 GETALEPGELITAVRLPAPPAGAGSAYLKVGRRASDAIALVSVAVALRLDGGT--IRDARIALGGVAPTPWRAREAEAAL 232
|
250 260 270
....*....|....*....|....*....|....*...
gi 77682555 476 LSKSWNEELLQDVCAGLAEELHLAPDAPGGmVEFRRTL 513
Cdd:COG1319 233 AGKPLSEEAIEAAAEAAAAAADPIDDVRAS-AEYRRHL 269
|
|
| glyceraldDH_gamma |
NF041020 |
glyceraldehyde dehydrogenase subunit gamma; |
13-167 |
4.20e-31 |
|
glyceraldehyde dehydrogenase subunit gamma;
Pssm-ID: 468949 [Multi-domain] Cd Length: 162 Bit Score: 120.29 E-value: 4.20e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 13 VNGKKVvEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYdrlqnkivhfSVNACLTPICSLHHVAVTTVE 92
Cdd:NF041020 15 VNGVWY-EAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGK----------SVKSCTVLAVQADGAEITTIE 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 77682555 93 GIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAK 167
Cdd:NF041020 84 GLSKDGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQ 158
|
|
| CO_deh_flav_C |
pfam03450 |
CO dehydrogenase flavoprotein C-terminal domain; |
421-525 |
1.10e-27 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 460921 [Multi-domain] Cd Length: 102 Bit Score: 108.03 E-value: 1.10e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 421 SAFKQASRREDDIAKVTSGMRVLFKPGTteVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQDVCAGLAEELHLaP 500
Cdd:pfam03450 1 AAYKQAKRRDDDIAIVNAAFRVRLDGGT--VEDARIAFGGVAPTPIRATEAEAALIGKPWDEETLEAAAALLLEDLSP-L 77
|
90 100
....*....|....*....|....*
gi 77682555 501 DAPGGMVEFRRTLTLSFFFKFYLTV 525
Cdd:pfam03450 78 SDPRGSAEYRRHLARSLLFRFLLEA 102
|
|
| 4hydroxCoAred |
TIGR03193 |
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ... |
13-166 |
1.07e-25 |
|
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.
Pssm-ID: 132237 [Multi-domain] Cd Length: 148 Bit Score: 104.19 E-value: 1.07e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 13 VNGKKvvEKNADPETTLLV-YLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLqnkivhfsvnACLTPICSLHHVAVTTV 91
Cdd:TIGR03193 6 VNGRW--REDAVADNMLLVdYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRL----------ACSTLAHRVAGRKVETV 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 77682555 92 EGIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFA 166
Cdd:TIGR03193 74 EGLATNGRLSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEAAA 148
|
|
| pucE |
TIGR03198 |
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ... |
8-167 |
8.45e-24 |
|
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.
Pssm-ID: 132242 [Multi-domain] Cd Length: 151 Bit Score: 98.77 E-value: 8.45e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 8 ELVFFVNGKKVvEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISkydrlqNKIVhfsvNACLTPICSLHHVA 87
Cdd:TIGR03198 3 QFRFTVNGQAW-EVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLID------GKLA----NACLTMAYQADGHE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 88 VTTVEGIGNtKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAK 167
Cdd:TIGR03198 72 ITTIEGIAE-NELDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSACRIRR 150
|
|
| CO_deh_flav_C |
smart01092 |
CO dehydrogenase flavoprotein C-terminal domain; |
422-525 |
1.74e-23 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 215021 [Multi-domain] Cd Length: 102 Bit Score: 96.15 E-value: 1.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 422 AFKQASRREDDIAKVTSGMRVLFKPGTteVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQDVCAGLAEELHLAPD 501
Cdd:smart01092 1 AYKKSRRRDGDIALVSAAVALTLDGGR--VTEARIALGGVAPTPKRAAEAEAALVGKPLTDEALARAAAAALAQDFTPLS 78
|
90 100
....*....|....*....|....
gi 77682555 502 APGGMVEFRRTLTLSFFFKFYLTV 525
Cdd:smart01092 79 DMRASAEYRRQLAANLLRRALLEA 102
|
|
| Se_dep_XDH |
TIGR03311 |
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ... |
11-167 |
1.71e-21 |
|
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 132354 [Multi-domain] Cd Length: 848 Bit Score: 101.46 E-value: 1.71e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 11 FFVNGKKVVeknADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYdrlqnkivhfSVNACLTPICSLHHVAVTT 90
Cdd:TIGR03311 3 FIVNGREVD---VNEEKKLLEFLREDLRLTGVKNGCGEGACGACTVIVNGK----------AVRACRFTTAKLAGKEITT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 91 VEGigntkkLHPVQERI-----AKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTF 165
Cdd:TIGR03311 70 VEG------LTEREKDVyawafAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAVRLA 143
|
..
gi 77682555 166 AK 167
Cdd:TIGR03311 144 AK 145
|
|
| PRK11433 |
PRK11433 |
aldehyde oxidoreductase 2Fe-2S subunit; Provisional |
8-160 |
2.02e-19 |
|
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
Pssm-ID: 236910 [Multi-domain] Cd Length: 217 Bit Score: 88.29 E-value: 2.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 8 ELVFFVNGKkVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYdrlqnkivhfSVNACLTpICSLHH-V 86
Cdd:PRK11433 51 PVTLKVNGK-TEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGR----------RLNACLT-LAVMHQgA 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 87 AVTTVEGIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRN---------------KPEPTVEEIENAFQGNLCR 151
Cdd:PRK11433 119 EITTIEGLGSPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKEikdgipshvtvdltaAPELTADEIRERMSGNICR 198
|
....*....
gi 77682555 152 CTGYRPILQ 160
Cdd:PRK11433 199 CGAYSNILE 207
|
|
| PRK09971 |
PRK09971 |
xanthine dehydrogenase subunit XdhB; Provisional |
240-459 |
2.48e-19 |
|
xanthine dehydrogenase subunit XdhB; Provisional
Pssm-ID: 182175 [Multi-domain] Cd Length: 291 Bit Score: 90.10 E-value: 2.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 240 QVSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEG-ISFGAACPLSLVES------ 312
Cdd:PRK09971 9 EAATLEEAIELLADNPQAKLIAGGTDVLIQLHHHNDRYRHLVSIHNIAELRGITLAEDGsIRIGAATTFTQIIEdpiiqk 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 313 ---VLADAIATLpeqrtevfrgvmeqlrwfAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMdH 389
Cdd:PRK09971 89 hlpALAEAAVSI------------------GGPQIRNVATIGGNICNGATSADSAPPLFALDAKLEIHSPNGVRFVPI-N 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 77682555 390 TFFPGYRRTLLSPEEILVSIVIP---YSRKGEFFsaFKQASRREDDIAkvTSGMRVLFKPGTTEVQELSLCFG 459
Cdd:PRK09971 150 GFYTGPGKVSLEHDEILVAFIIPpepYEHAGGAY--IKYAMRDAMDIA--TIGCAVLCRLDNGNFEDLRLAFG 218
|
|
| PRK09908 |
PRK09908 |
xanthine dehydrogenase iron sulfur-binding subunit XdhC; |
88-160 |
8.91e-18 |
|
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
Pssm-ID: 182139 [Multi-domain] Cd Length: 159 Bit Score: 81.89 E-value: 8.91e-18
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 77682555 88 VTTVEGIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLL---RNKPePTVEEIENAFQGNLCRCTGYRPILQ 160
Cdd:PRK09908 76 IRTLEGEAKGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLakpREKP-LTITEIRRGLAGNLCRCTGYQMIVN 150
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
73-160 |
4.13e-05 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 48.29 E-value: 4.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77682555 73 VNACLTPICSLHHVAVTTVEGIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRC 152
Cdd:PRK09800 56 VNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSRD 135
|
....*...
gi 77682555 153 TGYRPILQ 160
Cdd:PRK09800 136 AGWQQYYQ 143
|
|
| |
