|
Name |
Accession |
Description |
Interval |
E-value |
| mam_aldehyde_ox |
TIGR02969 |
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ... |
5-1333 |
0e+00 |
|
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain] Cd Length: 1330 Bit Score: 2852.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 5 QLLFYVNGQKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKAIRHHPVNACLTPICSLHGTA 84
Cdd:TIGR02969 2 ELLFYVNGRKVVEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPSTKSIRHHPVNACLTPICSLYGAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 85 VTTVEGLGNTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFC 164
Cdd:TIGR02969 82 VTTVEGIGSTRTRLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 165 KASGCCQSKENGVCCLDQEINGLAESQEEDKTSPELFSEEEFLPLDPTQELIFPPELMRIAEKQPPKTRVFYGERVTWIS 244
Cdd:TIGR02969 162 KTSGCCQSKENGVCCLDQGINGLPEFEEGDETSPELFSEEEFLPLDPTQELIFPPELMRMAEKQPQRTRVFYSERMMWIS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 245 PVTLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDGLTLGAGLSLDQVKDILADIVQK 324
Cdd:TIGR02969 242 PVTLKELLEAKFKYPQAPVVMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHTGDGLTLGAGLSLAQVKDILADVVQK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 325 LPEEKTQTYRALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLSKDGERRIPLSEEFLRKCPEADL 404
Cdd:TIGR02969 322 LPEETTQTYRALLKHLGTLAGSQIRNMASLGGHIISRHLDSDLNPLLAVGNCTLNLLSKEGKRQIPLSEQFLSKCPDADL 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 405 KPQEVLVSVNIPWSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFREGGGVIEELSILYGGVGSTIISAKNSCQRLIGRPW 484
Cdd:TIGR02969 402 KPQEILVSVNIPYSRKWEFVSAFRQAQRQQNALAIVNSGMRVFFGEGDGIIRELSISYGGVGPTTICAKNSCQKLIGRPW 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 485 NEGMLDTACRLVLDEVTLAASAPGGKVEFKRTLIISFLFKFYLEVSQGLKREDPGHSPSLAGNHESALDDLHSKHPWRTL 564
Cdd:TIGR02969 482 NEEMLDTACRLILDEVSLAGSAPGGKVEFKRTLIISFLFKFYLEVSQILKRMDPGHYPSLADKYESALEDLHSKHHWSTL 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 565 THQNVDPAQLPQDPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITAD 644
Cdd:TIGR02969 562 KHQNVDSMQLPQDPIGHPIMHLSGVKHATGEAIYCDDMPAVDQELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITAE 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 645 HLQEANTFGTETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLAPLILTIEEAIQHKSFFKSERKLECGNVD 724
Cdd:TIGR02969 642 HLQDANTFGTEKLLATDKVHCVGQLVCAVIADSEVQAKQAAKHVKIVYRDLEPLILTIEEAIQHKSFFEPERKLEYGNVD 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 725 EAFKIVDQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGG 804
Cdd:TIGR02969 722 EAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKYIQDIVAATLKLPVNKVMCHVRRVGGAFGG 801
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 805 KVGKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDESLWVIEM 884
Cdd:TIGR02969 802 KVGKTSIMAAITAFAANKHGRAVRCTLERGEDMLITGGRHPYLGKYKAGFMNDGRIVALDVEHYSNGGSSLDESLWVIEM 881
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 885 GLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMYKHVDTTHYKQEFS 964
Cdd:TIGR02969 882 GLLKMDNAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAGLITEACITEVAAKCGLSPEKVRTINMYKEIDQTPYKQEIN 961
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 965 AKALSECWRECMAKCSYFERKAAIGKFNAENSWKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYLDGSALVSHGGIEMGQ 1044
Cdd:TIGR02969 962 AKNLFQCWRECMAKSSYSERKVAVEKFNAENYWKKRGLAVIPLKFPVGLGSVAMGQAAALVHIYLDGSVLVTHGGIEMGQ 1041
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1045 GVHTKMIQVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDWAQTA 1124
Cdd:TIGR02969 1042 GVHTKMIQVVSRELKMPMSNVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDWAQTA 1121
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1125 FDQSISLSAVGYFRGYESNIDWEKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHSINPALDIGQVEGAFI 1204
Cdd:TIGR02969 1122 FDQSISLSAVGYFRGYESNINWEKGEGHPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGHSINPALDIGQVEGAFI 1201
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1205 QGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVKA 1284
Cdd:TIGR02969 1202 QGMGLYTIEELSYSPQGILYSRGPNQYKIPAICDIPTELHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVRA 1281
|
1290 1300 1310 1320
....*....|....*....|....*....|....*....|....*....
gi 110347467 1285 ARQERGISGPWKLNSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNIPV 1333
Cdd:TIGR02969 1282 ARQERGLSGPWKLTSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNVPV 1330
|
|
| PLN02906 |
PLN02906 |
xanthine dehydrogenase |
23-1316 |
0e+00 |
|
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain] Cd Length: 1319 Bit Score: 1352.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 23 EMMLLPYLRkNLRLTGTKYGCGGGGCGACTVMISRYNPSTKAIRHHPVNACLTPICSLHGTAVTTVEGLGNTRTRLHPIQ 102
Cdd:PLN02906 1 HQTLLEYLR-DLGLTGTKLGCGEGGCGACTVMVSHYDRKTGKCVHYAVNACLAPLYSVEGMHVITVEGIGNRRDGLHPVQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 103 ERIAKCHGTQCGFCTPGMVMSMYALLRNHPE-PTLDQLTDALGGNLCRCTGYRPIIDACKTFCKA--------SGCCQSK 173
Cdd:PLN02906 80 EALASMHGSQCGFCTPGFIMSMYALLRSSKTpPTEEQIEECLAGNLCRCTGYRPILDAFRVFAKTddalytgvSSLSLQD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 174 ENGVC--------CLDQEINGLAESQEeDKTSPELFSEEEFlPLDPTQELIFPPELMRIAEkQPPKTRVFYGerVTWISP 245
Cdd:PLN02906 160 GEPICpstgkpcsCGSKTTSAAGTCKS-DRFQPISYSEIDG-SWYTEKELIFPPELLLRKL-TPLKLLGNGG--LTWYRP 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 246 VTLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDGLTLGAGLSLDQVKDILADIVQKL 325
Cdd:PLN02906 235 TSLQHLLELKAEYPDAKLVVGNTEVGIEMRFKNAQYPVLISPTHVPELNAIKVKDDGLEIGAAVRLSELQNLFRKVVKER 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 326 PEEKTQTYRALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLSKDG-ERRIPLSEEFL--RKcpeA 402
Cdd:PLN02906 315 PAHETSACKAFIEQLKWFAGTQIRNVASIGGNICTASPISDLNPLWMAAGATFVIISCDGdIRSVPASDFFLgyRK---V 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 403 DLKPQEVLVSVNIPWSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFREGGG--VIEELSILYGGVGSTIISAKNSCQRLI 480
Cdd:PLN02906 392 DLKPDEILLSVFLPWTRPFEYVKEFKQAHRRDDDIAIVNAGMRVKLEEKDGewIVSDASIAYGGVAPLSVSARKTEEFLI 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 481 GRPWNEGMLDTACRLVLDEVTLAASAPGGKVEFKRTLIISFLFKFYLEVSQGLKredpGHSPSLAGNHE---SALDDLHs 557
Cdd:PLN02906 472 GKPWNKETLQDALKVLQKDILIKEDAPGGMVEFRKSLALSFFFKFFLWVSHQLE----ADGSTIETFPEshlSAAQPFP- 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 558 khpwRTLTHQNVDPAQLPQ-DPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPG 636
Cdd:PLN02906 547 ----RPSSVGMQDYETVKQgTAVGQPEVHLSAELQVTGEAEYADDIPMPPNTLHAALVLSTKPHARILSIDDSEAKSSPG 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 637 VVDIITADHLQEANTFGT----ETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLaPLILTIEEAIQHKSFF 712
Cdd:PLN02906 623 FAGIFLAKDVPGDNMIGPvvhdEELFATDVVTCVGQVIGVVVADTQENAKAAARKVKVEYEEL-PAILSIEEAIEAGSFH 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 713 -KSERKLECGNVDEAFK--IVDQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKYIQDIVAATLKLSAN 789
Cdd:PLN02906 702 pNTERRLEKGDVELCFAsgQCDRIIEGEVQMGGQEHFYLEPNSSLVWTSDSGNEVHMISSTQAPQKHQKYVAHVLGLPMS 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 790 KVMCHVRRVGGAFGGKVGKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYC 869
Cdd:PLN02906 782 KVVCKTKRIGGGFGGKETRSAFIAAAAAVPAYLLNRPVKLTLDRDVDMMITGQRHAFLGKYKVGFTNEGKILALDLEIYN 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 870 NGGCSLDESLWVIEMGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTIN 949
Cdd:PLN02906 862 NGGNSLDLSGAVLERAMFHSDNVYEIPNVRIVGNVCFTNFPSNTAFRGFGGPQGMLITENWIQRIAVELNKSPEEIREMN 941
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 950 MYKHVDTTHYKQEFSAKALSECWRECMAKCSYFERKAAIGKFNAENSWKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYL 1029
Cdd:PLN02906 942 FQGEGSVTHYGQVLQHCTLPQLWDELKVSCDFLKRREEVDEFNAKNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYT 1021
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1030 DGSALVSHGGIEMGQGVHTKMIQVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPII 1109
Cdd:PLN02906 1022 DGTVLVTHGGVEMGQGLHTKVAQVAASAFNIPLSSVFISETSTDKVPNASPTAASASSDMYGAAVLDACEQIKARMEPVA 1101
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1110 SKNPQGTWKDWAQTAFDQSISLSAVGYFRGYESNIDWEKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHS 1189
Cdd:PLN02906 1102 SKLNFSSFAELVTACYFQRIDLSAHGFYITPDIGFDWKTGKGNPFNYFTYGAAFAEVEIDTLTGDFHTRRVDIVMDLGYS 1181
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1190 INPALDIGQVEGAFIQGMGLYTIEELSYS-------PQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKG 1262
Cdd:PLN02906 1182 INPAIDIGQIEGAFVQGLGWVALEELKWGdaahkwiRPGSLFTCGPGTYKIPSVNDIPFKFNVSLLKGAPNPKAIHSSKA 1261
|
1290 1300 1310 1320 1330
....*....|....*....|....*....|....*....|....*....|....
gi 110347467 1263 LGESGVFLGCSVFFAIHDAVKAARQERGISGPWKLNSPLTPEKIRMACEDKFTK 1316
Cdd:PLN02906 1262 VGEPPFFLAASVFFAIKDAIKAARAEVGLHGWFPLDTPATPERIRMACGDEITA 1315
|
|
| XdhB |
COG4631 |
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and ... |
570-1311 |
0e+00 |
|
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and metabolism];
Pssm-ID: 443669 [Multi-domain] Cd Length: 769 Bit Score: 842.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 570 DPAQLPQDPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQEA 649
Cdd:COG4631 5 LSPPPAAGAVGKSLPHESARLHVTGEARYIDDLPEPAGTLHAAPGLSPVAHARILSIDLSAVRAAPGVVAVLTAADIPGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 650 NTFGT----ETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLAPlILTIEEAIQHKSFFKSERKLECGNVDE 725
Cdd:COG4631 85 NDIGPiihdEPLLADGEVEYVGQPVFAVVAESREAARRAARLAKIEYEELPA-ILTIEEALAAGSFVLPPHTLRRGDADA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 726 AFKIVDQILEGEIHIGGQEHFYMETQSMLVVPkGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGGK 805
Cdd:COG4631 164 ALAAAPHRLEGEFEIGGQEHFYLEGQIALAIP-GEDGGMLVHSSTQHPSEVQHLVAHVLGVPMHAVTVEVRRMGGGFGGK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 806 VGKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDESLWVIEMG 885
Cdd:COG4631 243 ESQAALFAALAALAARKTGRPVKLRLDRDDDMVMTGKRHPFRIDYEVGFDDDGRILGLDITLAARCGWSADLSGPVADRA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 886 LLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMY--KHVDTTHYKQEF 963
Cdd:COG4631 323 MFHADNAYYLPAVRITGHRCKTNTQSNTAFRGFGGPQGMLAIERVIDDIARALGLDPLDVRRRNFYgpAERNTTPYGQPV 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 964 SAKALSECWRECMAKCSYFERKAAIGKFNAENSWKKRGMAVIPLKFpvGIG--SVAMGQAAALVHIYLDGSALVSHGGIE 1041
Cdd:COG4631 403 EDNILHELVDELEESSDYAARRAAIAAFNAASPVLKRGLALTPVKF--GISftATHLNQAGALVHVYTDGSVQLNHGGTE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1042 MGQGVHTKMIQVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEP-------------- 1107
Cdd:COG4631 481 MGQGLHTKVAQVVADELGVPLERVRITATDTDKVPNTSATAASSGSDLNGMAAQDACRQIRERLAAfaaellgvepedvr 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1108 -----IISKNPQGTWKDWAQTAFDQSISLSAVGYFRgyESNIDW--EKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRT 1180
Cdd:COG4631 561 fadgrVRVGGQSLSFAELVKAAYLARVSLSATGFYK--TPKIHWdrATGQGRPFYYFAYGAAVSEVEIDTLTGEYRVLRV 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1181 NIVMDVGHSINPALDIGQVEGAFIQGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSS 1260
Cdd:COG4631 639 DILHDVGRSLNPAIDIGQIEGGFVQGMGWLTTEELVWDDKGRLLTHAPSTYKIPAASDRPEDFNVALLERPNREDTIYRS 718
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 110347467 1261 KGLGESGVFLGCSVFFAIHDAVKAARQERGISgpwKLNSPLTPEKIRMACE 1311
Cdd:COG4631 719 KAVGEPPLMLGISVFEALRDAVAAVGDYRVSP---PLDAPATPERVLMAVE 766
|
|
| PLN00192 |
PLN00192 |
aldehyde oxidase |
6-1288 |
0e+00 |
|
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain] Cd Length: 1344 Bit Score: 694.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 6 LLFYVNGQKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKAIRHHPVNACLTPICSLHGTAV 85
Cdd:PLN00192 6 LVFAVNGERFELSSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLLSKYDPVLDQVEDFTVSSCLTLLCSVNGCSI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 86 TTVEGLGNTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALL-------RNHPEPTLDQLT-----DALGGNLCRCTGY 153
Cdd:PLN00192 86 TTSEGLGNSKDGFHPIHKRFAGFHASQCGFCTPGMCISLFSALvnadktdRPEPPSGFSKLTvveaeKAVSGNLCRCTGY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 154 RPIIDACKTFckASGccqskengvccLDQEINGL------AESQEEDKTSpelfseeefLPL-DPTQELIFPPELMRIAE 226
Cdd:PLN00192 166 RPIVDACKSF--AAD-----------VDIEDLGLnsfwkkGESEEAKLSK---------LPPyNHSDHICTFPEFLKKEI 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 227 KqppKTRVFYGERVTWISPVTLKELVE----AKFKYPQAPIVMGYTSVG--PEVKFKGVFhpIIISpdRIEELGVISQAR 300
Cdd:PLN00192 224 K---SSLLLDSSRYRWYTPVSVEELQSllesNNFDGVSVKLVVGNTGTGyyKDEELYDKY--IDIR--HIPELSMIRRDE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 301 DGLTLGAGLSLDQVKDILADivqklpEEKTQ-TYRALLKHLRTLAGSQIRNMASLGGHIV---SRHLDSDLNP-LLAVGN 375
Cdd:PLN00192 297 KGIEIGAVVTISKAIEALRE------ESKSEyVFKKIADHMEKIASRFVRNTGSIGGNLVmaqRKQFPSDIATiLLAAGS 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 376 cTLNLLSKDGERRIPLsEEFLRKcPEADLKpqEVLVSVNIP-WSRKWE-----FVSAFRQAQRQQ-NALAIVNSGM--RV 446
Cdd:PLN00192 371 -TVNIQNASKREKLTL-EEFLER-PPLDSK--SLLLSVEIPsWTSSSGsdtklLFETYRAAPRPLgNALPYLNAAFlaEV 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 447 LFRE--GGGVIEELSILYGGVGST-IISAKNSCQRLIGRPWNEGMLDTACRLVLDEVTLA--ASAPggkvEFKRTLIISF 521
Cdd:PLN00192 446 SQDAssGGIVVNDCRLAFGAYGTKhAIRARKVEEFLTGKVLSDSVLYEAVRLLKGIVVPEdgTSHP----EYRSSLAVGF 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 522 LFKFYLEVSQGLKREDPGHSPSLAGNHESALDDLHSKHPWRTLTHQNVDPAQLPQDPIGRPIMHLSGIKHATGEAIYCDD 601
Cdd:PLN00192 522 LFDFLSPLIESNAKSSNGWLDGGSNTKQNPDQHDDVKKPTLLLSSKQQVEENNEYHPVGEPIKKVGAALQASGEAVYVDD 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 602 MPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQE------ANT-FGTETFLATDEVHCVGHLVCAVI 674
Cdd:PLN00192 602 IPSPKNCLYGAFIYSTKPLARVKGIKFKSNLVPQGVLAVITFKDIPKggqnigSKTiFGPEPLFADEVTRCAGQRIALVV 681
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 675 ADSETRAKQAAKQVKVVY--QDLAPLILTIEEAIQHKSFFKSERKLECGNVDEAFKIVDQ----ILEGEIHIGGQEHFYM 748
Cdd:PLN00192 682 ADTQKHADMAANLAVVEYdtENLEPPILTVEDAVKRSSLFEVPPFLYPKPVGDISKGMAEadhkILSAEIKLGSQYYFYM 761
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 749 ETQSMLVVPKgEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGGKVGKTSILAAITAFAASKHGRAVR 828
Cdd:PLN00192 762 ETQTALALPD-EDNCIVVYSSTQCPEYVHSVIARCLGIPEHNVRVITRRVGGGFGGKAVKSMPVATACALAAFKLQRPVR 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 829 CILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDESLwVIEMGLLKLDNAYKFPNLRCRGWACRTN 908
Cdd:PLN00192 841 MYLNRKTDMIMAGGRHPMKITYSVGFKSDGKITALHLDILINAGISPDISP-IMPRNIIGALKKYDWGALSFDIKVCKTN 919
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 909 LPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMYKH----VDTTHYKQEFSAKALSECWRECMAKCSYFER 984
Cdd:PLN00192 920 LSSRSAMRAPGEVQGSYIAEAIIEHVASTLSMDVDSVRKINLHTYeslkLFYGDSAGEPSEYTLPSIWDKLASSSEFKQR 999
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 985 KAAIGKFNAENSWKKRGMAVIPLkfpvgIGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQVVSRELRM--PM 1062
Cdd:PLN00192 1000 TEMVKEFNRSNKWKKRGISRVPI-----VHEVMLRPTPGKVSILSDGSIAVEVGGIEIGQGLWTKVKQMAAFGLGMikCD 1074
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1063 SSVHL----RGTSTETVPNTNAS--GGSVVADLNGLAVKDACQTLLKRLEPI----ISKNPQGTWKDWAQTAFDQSISLS 1132
Cdd:PLN00192 1075 GGEDLldkiRVIQSDTLSMIQGGftAGSTTSESSCEAVRLCCVILVERLKPIkerlQEQMGSVTWDMLISQAYMQSVNLS 1154
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1133 AVGYFrgyesnidweKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHSINPALDIGQVEGAFIQGMGLYTI 1212
Cdd:PLN00192 1155 ASSYY----------TPDPSSMEYLNYGAAVSEVEVDLLTGETTILRSDIIYDCGQSLNPAVDLGQIEGAFVQGIGFFML 1224
|
1290 1300 1310 1320 1330 1340 1350
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 110347467 1213 EELSYSPQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVKAARQE 1288
Cdd:PLN00192 1225 EEYTTNSDGLVVTDGTWTYKIPTVDTIPKQFNVEILNSGHHKKRVLSSKASGEPPLLLAASVHCATRAAIREARKQ 1300
|
|
| xanthine_xdhB |
TIGR02965 |
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the ... |
579-1312 |
0e+00 |
|
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the molybdopterin-containing large subunit (or, in, eukaryotes, the molybdopterin-binding domain) of xanthine dehydrogenase, and enzyme that reduces the purine pool by catabolizing xanthine to urate. This model is based primarily on bacterial sequences; it does not manage to include all eukaryotic xanthine dehydrogenases and thereby discriminate them from the closely related enzyme aldehyde dehydrogenase. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274367 [Multi-domain] Cd Length: 758 Bit Score: 682.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 579 IGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQEANTFGT---- 654
Cdd:TIGR02965 1 VGTSLKHESAHKHVAGTAVYIDDIPEPAGTLHAALGLSTRAHARITSMDLSAVRAAPGVVDVLTAADIPGENDISPiihd 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 655 ETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLaPLILTIEEAIQHKS-FFKSERKLECGNVDEAFKIVDQI 733
Cdd:TIGR02965 81 DPLLADGKVEFVGQPIFAVVATSRDAARRAARLAKIEYEEL-PAVLDIEEALAAGSrLVTPPLTLERGDAAAALAAAPHR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 734 LEGEIHIGGQEHFYMETQSMLVVPkGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGGKVGKTSILA 813
Cdd:TIGR02965 160 LSGTMRIGGQEHFYLEGQIALAVP-GEDGGMHVWSSTQHPSEVQHLVAHVLGVPSHAVTVEVRRMGGGFGGKETQANLFA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 814 AITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDESLWVIEMGLLKLDNAY 893
Cdd:TIGR02965 239 CLAAVAARKTGRPVKLRPDRDDDMMITGKRHDFRVDYDVGFDDEGRILGVDIDMAARCGFSADLSGPVTDRALFHADNAY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 894 KFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMY--KHVDTTHYKQEFSAKALSEC 971
Cdd:TIGR02965 319 FLPDVTITSHPLKTNTQSNTAFRGFGGPQGMVAIERIMDEVARALGKDPLEVRKRNFYgkDERNVTPYHQTVEDNIIHEI 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 972 WRECMAKCSYFERKAAIGKFNAENSWKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMI 1051
Cdd:TIGR02965 399 IEELEASSDYAARRAAIRAFNATSPVLKKGIALTPVKFGISFTVTHLNQAGALVHVYTDGSIHLNHGGTEMGQGLNTKVA 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1052 QVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGT--------------- 1116
Cdd:TIGR02965 479 QVVAEEFQVDIDRVKITATDTGKVPNTSATAASSGSDLNGMAAQDAARQIKERLVEFAAEKWQVPeedvrfapnhvrvge 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1117 ----WKDWAQTAFDQSISLSAVGYFRGYESNIDWEKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHSINP 1192
Cdd:TIGR02965 559 qrvpFAELVQQAYFARVQLSSTGFYKTPKIHWDRAKGRGRPFYYFAYGAACSEVSVDTLTGEYKVLRADILHDVGRSLNP 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1193 ALDIGQVEGAFIQGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEH-SNTLYSSKGLGESGVFLG 1271
Cdd:TIGR02965 639 AIDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPAASDRPKDFNVRLFEWGENrEDTIHRSKAVGEPPLMLG 718
|
730 740 750 760
....*....|....*....|....*....|....*....|.
gi 110347467 1272 CSVFFAIHDAVKAARQERGISgpwKLNSPLTPEKIRMACED 1312
Cdd:TIGR02965 719 ISVLFAISDAVASVADYRVCP---RLDAPATPERVLMAVEA 756
|
|
| CoxL |
COG1529 |
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ... |
579-1309 |
1.17e-151 |
|
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain] Cd Length: 741 Bit Score: 476.26 E-value: 1.17e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 579 IGRPIMHLSGIKHATGEAIYCDDMPaVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLqEANTFGTETF- 657
Cdd:COG1529 10 IGKPVPRVDGPAKVTGRARYTDDIR-LPGMLYAAVVRSPHAHARIKSIDTSAALALPGVVAVLTGEDL-PGLKFGLPGPd 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 658 -----LATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLaPLILTIEEAI---------QHKSFFKSERKLECGNV 723
Cdd:COG1529 88 pdqppLADDKVRYVGEPVAAVVAETREAARDAAELIKVEYEPL-PAVVDPEAALapgaplvheELPGNVAAEWRGERGDV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 724 DEAFKIVDQILEGEIHIGGQEHFYMETQSMLVVPKGeDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFG 803
Cdd:COG1529 167 DAAFAEADVVVEATYTTPRLAHAPMEPRAAVAEWDG-DGRLTVWASTQGPHLVRRALARALGLPPEKVRVIAPDVGGGFG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 804 GKvGKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDESLWVIE 883
Cdd:COG1529 246 GK-LDVYPEEVLAALAARKLGRPVKLVLTREEDFLADTHRHATVQRVRLGADKDGKITALRHDVVADTGAYASFGEAVLP 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 884 MGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMYKHVDTTHYKQEF 963
Cdd:COG1529 325 LGATMATGPYAIPNVRVEARAVYTNTPPTGAYRGPGRPQAAFALESAMDELAEELGMDPVELRLRNLIRPGDFPPTGQPY 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 964 SAKALSECWRECMAKCSYFERKAAIGKfnAENSWKK-RGMAVIplkfpVGIGSVAMGQAAALVHIYLDGSALVSHGGIEM 1042
Cdd:COG1529 405 DSGRLAECLEKAAEAFGWGERRARPAE--ARAGKLRgIGVAAY-----IEGSGGGGDPESARVRLNPDGSVTVYTGATDI 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1043 GQGVHTKMIQVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQG-----TW 1117
Cdd:COG1529 478 GQGHETVLAQIAAEELGVPPEDVRVVLGDTDLTPYGGGTGGSRSTAVGGSAVRKAAEKLREKLLELAAHLLGAdpedlEF 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1118 KDWAQTAFDQSISLSAVGYFRGYESNIDWEKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHSINPALDIG 1197
Cdd:COG1529 558 EDGRVRVPGRSVSLAELAAAAYYGGLEATGTYDPPTYPTYSFGAHVAEVEVDPETGEVRVLRVVAVHDCGRVINPLLVEG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1198 QVEGAFIQGMG--LYtiEELSYSPQGTLYSRGPNQYKIPAICDIPtEMHISFLpPSEHSNTLYSSKGLGESGVflgCSVF 1275
Cdd:COG1529 638 QVEGGVVQGIGqaLY--EELVYDEDGQLLNANFADYLVPRAADVP-EIEVIFV-ETPDPTNPLGAKGVGEPGT---IGVA 710
|
730 740 750
....*....|....*....|....*....|....
gi 110347467 1276 FAIHDAVKAArqergiSGPWKLNSPLTPEKIRMA 1309
Cdd:COG1529 711 PAIANAVYDA------TGVRIRDLPITPEKVLAA 738
|
|
| xanthine_xdhA |
TIGR02963 |
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ... |
8-529 |
4.81e-130 |
|
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274365 [Multi-domain] Cd Length: 467 Bit Score: 408.97 E-value: 4.81e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 8 FYVNGQKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKaIRHHPVNACLTPICSLHGTAVTT 87
Cdd:TIGR02963 3 FFLNGETVTLSDVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVGELVDGGK-LRYRSVNACIQFLPSLDGKAVVT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 88 VEGLGNTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACkTFCKAS 167
Cdd:TIGR02963 82 VEDLRQPDGRLHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILDAA-EAAFDY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 168 GCCQskengvccldqeinglaesqeedktspelfseeeflPLDPTQELIFpPELMRIAEKQpPKTRVFYGERVtwISPVT 247
Cdd:TIGR02963 161 PCSD------------------------------------PLDADRAPII-ERLRALRAGE-TVELNFGGERF--IAPTT 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 248 LKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDGLTLGAGLSLDQVKDILADIVQKLPE 327
Cdd:TIGR02963 201 LDDLAALKAAHPDARIVAGSTDVGLWVTKQMRDLPDVIYVGQVAELKRIEETDDGIEIGAAVTLTDAYAALAKRYPELGE 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 328 EktqtyrallkhLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLSKDGERRIPLSEEFL--RKcpeADLK 405
Cdd:TIGR02963 281 L-----------LRRFASLQIRNAGTLGGNIANGSPIGDSPPALIALGARLTLRKGEGRRTLPLEDFFIdyGK---TDRQ 346
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 406 PQEVLVSVNIPWSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFRegGGVIEELSILYGGVGSTIISAKNSCQRLIGRPWN 485
Cdd:TIGR02963 347 PGEFVEALHVPRPTPGERFRAYKISKRFDDDISAVCAAFNLELD--GGVVAEIRIAFGGMAATPKRAAATEAALLGKPWN 424
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 110347467 486 EGMLDTACRLVLDEVT-LAASAPGGkvEFKRTLIISFLFKFYLEV 529
Cdd:TIGR02963 425 EATVEAAMAALAGDFTpLSDMRASA--EYRLLTAKNLLRRFFLET 467
|
|
| MoCoBD_2 |
pfam20256 |
Molybdopterin cofactor-binding domain; |
974-1240 |
4.32e-107 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain] Cd Length: 282 Bit Score: 339.90 E-value: 4.32e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 974 ECMAKCSYFERKAAIGKFNAENswKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQV 1053
Cdd:pfam20256 1 KALELSDYDERRAEQAEFNRGN--RKRGIGIAPYVEGSGLGPGALNQAGALVRLNPDGSVTVYTGGTEMGQGLETKLAQI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1054 VSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISK--------------------NP 1113
Cdd:pfam20256 79 AAEALGIPPEDVRVVEGDTDTVPNGGGTGASRSTDVGGNAVLLAAEKLRERLLKIAAHlleaspedlefedgkvyvkgDP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1114 QG-TWKDWAQTAFDQSISLSAVGYFRGYesniDWEKGEGHPFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHSINP 1192
Cdd:pfam20256 159 RSvTFAELAAAAYGEGVGLSATGFYTPP----DDETGQGPPFAYYPYGAHAAEVEVDPETGEVRVLRYVAVHDCGRVINP 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 110347467 1193 ALDIGQVEGAFIQGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIP 1240
Cdd:pfam20256 235 AIVEGQIEGGFVQGIGLALMEELVYDEDGQLLTASLMDYKIPTAADIP 282
|
|
| MoCoBD_1 |
pfam02738 |
Molybdopterin cofactor-binding domain; |
719-950 |
9.02e-104 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain] Cd Length: 244 Bit Score: 329.03 E-value: 9.02e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 719 ECGNVDEAFKIVDQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRV 798
Cdd:pfam02738 14 EKGDVEAAFAEADHVVEGEYRTGRQEHFYMETRAALAVPDDEDGRLTVYSSTQGPHLVRRLVARVLGIPENKVRVIVPRV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 799 GGAFGGKVgKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDES 878
Cdd:pfam02738 94 GGGFGGKT-QSYPEEALAALAARKTGRPVKWVLDREEDMLATGHRHPFLIKYKVGADKDGKILALDVDLYADGGAYADLS 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 110347467 879 LWVIEMGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINM 950
Cdd:pfam02738 173 PAVPERALSHLDGPYKIPNVRVDGRAVYTNTPPNGAFRGFGRPQGMFALERLMDELAEELGMDPLELRRRNL 244
|
|
| XdhA |
COG4630 |
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ... |
8-532 |
2.01e-89 |
|
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];
Pssm-ID: 443668 [Multi-domain] Cd Length: 476 Bit Score: 298.59 E-value: 2.01e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 8 FYVNGQKVVEKNVDPEMMLLPYLRKNLRLtgtkygcggggcgactVMISRynPSTKAIRHHPVNACLTPICSLHGTAVTT 87
Cdd:COG4630 3 FLLNGELVELSDVPPTTTLLDWLREDRGLtgtkegcaegdcgactVVVGE--LDDGGLRYRAVNACILFLPQLDGKALVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 88 VEGLGNTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTfckas 167
Cdd:COG4630 81 VEGLAGPDGALHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIIDAARA----- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 168 gccqskengvccldqeingLAESQEEDKtspelFSEEEflpldptQELIfpPELMRIAEKQPpktrVFYGERV-TWISPV 246
Cdd:COG4630 156 -------------------MAEAPAPDP-----FAADR-------AAVA--AALRALADGET----VELGAGGsRFLAPA 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 247 TLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDGLTLGAGLSLDQVKDILADIvqkLP 326
Cdd:COG4630 199 TLDELAALLAAHPDARLVAGATDVGLWVTKQLRDLPPVIFLGRVAELRRIEETDDGLEIGAAVTLSDAEAALAAH---FP 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 327 EektqtYRALlkhLRTLAGSQIRNMASLGGHIVSrhlDS---DLNPLLAVGNCTLNLLSKDGERRIPLSEEFL--RKcpe 401
Cdd:COG4630 276 E-----LAEL---LRRFASRQIRNAGTLGGNIAN---GSpigDSPPALIALGAELVLRSGDGRRTLPLEDFFLgyRK--- 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 402 ADLKPQEVLVSVNIPWSRKWEFVSAFRQAQRQQNALAIVNSGMRVlfREGGGVIEELSILYGGVGSTIISAKNSCQRLIG 481
Cdd:COG4630 342 TDLQPGEFVEAIRIPLPAAGQRLRAYKVSKRFDDDISAVCAAFAL--TLDDGTVTEARIAFGGMAATPKRARAAEAALLG 419
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 110347467 482 RPWNEGMLDTACRLVLDEVT----LAASApggkvEFKRTLIISFLFKFYLEVSQG 532
Cdd:COG4630 420 QPWTEATVAAAAAALAQDFTplsdMRASA-----EYRLAVAANLLRRFFLETQGE 469
|
|
| PRK09970 |
PRK09970 |
xanthine dehydrogenase subunit XdhA; Provisional |
579-1306 |
2.03e-79 |
|
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain] Cd Length: 759 Bit Score: 278.50 E-value: 2.03e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 579 IGRPIMHLSGIKHATGEAIYCDDMPAVDReLFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLqEANTFGT---- 654
Cdd:PRK09970 3 IGKSIMRVDAIAKVTGRAKYTDDYVMAGM-LYAKYVRSPIAHGKVKSIDTEEARSLPGVEAVFTWEDV-PDIPFPTaghp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 655 -----------ETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLaPLILTIEEAIQ------HKSF--FKSE 715
Cdd:PRK09970 81 wsldpnhrdiaDRALLTRHVRHHGDAVAAVVARDELTAEKALKLIKVEYEEL-PVITDPEAALAegappiHNGRgnLLKQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 716 RKLECGNVDEAFKIVDQILEGEIHIGGQEHFYMETQSMLVVpKGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHV 795
Cdd:PRK09970 160 STMSTGNVQQTIKAADYQVQGHYETPIVQHCHMENVTSYAY-MEDDGRITIVSSTQIPHIVRRVVGQALGIPWGKVRVIK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 796 RRVGGAFGGKvgKTSILAAITAFAASK-HGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCS 874
Cdd:PRK09970 239 PYVGGGFGNK--QDVLEEPLAAFLTSKvGGRPVKVSLSREECFLATRTRHAFTIDIKMGVNRDGTLKGYSLDVLSNTGAY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 875 LDESLWVIEMGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMYK-- 952
Cdd:PRK09970 317 ASHGHSIASAGGNKVAYLYPRCAYKYSSKTVYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEFRLRNAAReg 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 953 HVDTTHYKQEFSAKaLSECWRECMAKCSYFERKAaigKFNAENSWKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYLDGS 1032
Cdd:PRK09970 397 DANPLSGKRIYSAG-LPECLEKGRKIFEWDKRRA---ECKNQQGNLRRGVGVACFSYTSGTWPVGLEIAGARLLMNQDGT 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1033 ALVSHGGIEMGQGVHTKMIQVVSRELRMPMSSVHLRGTSTETV----PNTNASGGSVVAdlnGLAVKDACqTLLKrlEPI 1108
Cdd:PRK09970 473 VQVQSGATEIGQGSDTVFSQMVAETVGIPVSDVRVISTQDTDVtpfdPGAYASRQSYVA---GPAIRKAA-LELK--EKI 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1109 ISKnpqgTWKDWAQTAFDQSISLSAVGYFR-----------GYESNIDWEKGEGHPFEY--------FVFGAACSEVEID 1169
Cdd:PRK09970 547 LAH----AAVMLHQSAMNLDIIDGHIVVKRpgeplmsleelAMDAYYHPERGGQITAESsiktttnpPAFGCTFVDVEVD 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1170 CLTGDHKNIRTNIVMDVGHSINPALDIGQVEGAFIQGMGLYTIEELSYSPQgTLYSRGPN--QYKIPAICDIPtEMHISF 1247
Cdd:PRK09970 623 IALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDEK-TGVVRNPNllDYKLPTMMDLP-QLESAF 700
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1248 LPPSEHSNTlYSSKGLGESGVflgCSVFFAIHDAVKAArqeRGISgpwkLNS-PLTPEKI 1306
Cdd:PRK09970 701 VEIYEPQSA-YGHKSLGEPPI---ISPAPAIRNAVLMA---TGVA----INTlPMTPQRL 749
|
|
| FAD_binding_5 |
pfam00941 |
FAD binding domain in molybdopterin dehydrogenase; |
239-418 |
4.95e-51 |
|
FAD binding domain in molybdopterin dehydrogenase;
Pssm-ID: 460007 [Multi-domain] Cd Length: 170 Bit Score: 177.35 E-value: 4.95e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 239 RVTWISPVTLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDGLTLGAGLSLDQVKDIL 318
Cdd:pfam00941 2 KFGYYRPASLAEALELLAAGPDAKLVAGGTSLGPLMKLRLARPDHLIDINGIPELRGIEETDGGLEIGAAVTLSEIAEPL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 319 adIVQKLPeektqtyrALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLSKDGERRIPLsEEFLRK 398
Cdd:pfam00941 82 --LREAYP--------ALSEALRKIASPQIRNVGTIGGNIANASPISDLPPALLALDAKVELRSGEGERTVPL-EDFFLG 150
|
170 180
....*....|....*....|
gi 110347467 399 CPEADLKPQEVLVSVNIPWS 418
Cdd:pfam00941 151 YGKTALEPGELITAVIIPLP 170
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
577-1306 |
3.15e-50 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 193.89 E-value: 3.15e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 577 DPIGRPIMHLSGIKHATGEAIYCDDMPAVDrELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITadHLQEAN---TFG 653
Cdd:PRK09800 170 EVIGKHYPKTDAAKMVQAKPCYVEDRVTAD-ACVIKMLRSPHAHALITHLDVSKAEALPGVVHVIT--HLNCPDiyyTPG 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 654 TETF---------LATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLAPlILTIEEAI------------------ 706
Cdd:PRK09800 247 GQSApepspldrrMFGKKMRHVGDRVAAVVAESEEIALEALKLIDVEYEVLKP-VMSIDEAMaedapvvhdepvvyvaga 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 707 ------QHKSFFKSERKL--------------------ECGNVDEAFKIVDQILEGEIHIGGQEHFYMETQsmlVVPKGE 760
Cdd:PRK09800 326 pdtledDNSHAAQRGEHMiinfpigsrprkniaasihgHIGDMDKGFADADVIIERTYNSTQAQQCPTETH---ICFTRM 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 761 DGE-IDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGGKvgKTSILAAITAFAASKHGRAVRCILERGEDMLI 839
Cdd:PRK09800 403 DGDrLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSK--QDILLEEVCAWATCVTGRPVLFRYTREEEFIA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 840 TGGRHPYLGKYKAGFMNDGRILALDVEHYCNGGCSLDESLWVIEMGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFG 919
Cdd:PRK09800 481 NTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYG 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 920 FPQAGLVTEACITEVAIKCGLspEQVRTINMYKHVDTTHYK--------------QEFSAKALSECWRECMAKCSYFERK 985
Cdd:PRK09800 561 APKGNFAITMALAELAEQLQI--DQLEIIERNRVHEGQELKilgaigegkaptsvPSAASCALEEILRQGREMIQWSSPK 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 986 AAIGkfnaenSWK-KRGMAVIPLKfpVGIGSVamGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQVVSRELRMPMSS 1064
Cdd:PRK09800 639 PQNG------DWHiGRGVAIIMQK--SGIPDI--DQANCMIKLESDGTFIVHSGGADIGTGLDTVVTKLAAEVLHCPPQD 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1065 VHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRL---------EPIisknpqgtwkdwaqtafdQSISLSAVG 1135
Cdd:PRK09800 709 VHVISGDTDHALFDKGAYASSGTCFSGNAARLAAENLREKIlfhgaqmlgEPV------------------ADVQLATPG 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1136 YFRGYESNIDW-------EKGEGH-----------PFEYFVFGAACSEVEIDCLTGDHKNIRTNIVMDVGHSINPALDIG 1197
Cdd:PRK09800 771 VVRGKKGEVSFgdiahkgETGTGFgslvgtgsyitPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALG 850
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 1198 QVEGAFIQGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIPTEMHiSFLPPSEHSNTLYSSKGLGESGVFlGCS--VF 1275
Cdd:PRK09800 851 QIYGATLRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFR-AVLVPSDDKVGPFGAKSISEIGVN-GAApaIA 928
|
810 820 830
....*....|....*....|....*....|.
gi 110347467 1276 FAIHDAVkaarqergisGPWKLNSPLTPEKI 1306
Cdd:PRK09800 929 TAIHDAC----------GIWLREWHFTPEKI 949
|
|
| CutS |
COG2080 |
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ... |
8-159 |
1.32e-43 |
|
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441683 [Multi-domain] Cd Length: 155 Bit Score: 155.64 E-value: 1.32e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 8 FYVNGQKVvEKNVDPEMMLLPYLRKNLRLtgtkygcggggcgactvmisrynPSTKA-------------IRHHPVNACL 74
Cdd:COG2080 6 LTVNGKPV-EVDVDPDTPLLDVLRDDLGL-----------------------TGTKFgcghgqcgactvlVDGKAVRSCL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 75 TPICSLHGTAVTTVEGLGnTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYR 154
Cdd:COG2080 62 TLAVQADGKEITTIEGLA-EDGELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYV 140
|
....*
gi 110347467 155 PIIDA 159
Cdd:COG2080 141 RIVRA 145
|
|
| Ald_Xan_dh_C |
pfam01315 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; |
593-695 |
1.10e-37 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain] Cd Length: 107 Bit Score: 136.98 E-value: 1.10e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 593 TGEAIYCDDMPAVDRElFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHL----QEANTFGTETFLATDEVHCVGH 668
Cdd:pfam01315 1 TGEAVYVDDIPAPGNL-YGAFVRSTIAHAKIVSIDTSAALALPGVVAVITAKDLpggnYNIGPIPLDPLFATDKVRHVGQ 79
|
90 100
....*....|....*....|....*..
gi 110347467 669 LVCAVIADSETRAKQAAKQVKVVYQDL 695
Cdd:pfam01315 80 PIAAVVADDEETARRAAKLVKVEYEEL 106
|
|
| Ald_Xan_dh_C |
smart01008 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ... |
593-695 |
3.38e-37 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain] Cd Length: 107 Bit Score: 135.34 E-value: 3.38e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 593 TGEAIYCDDMPaVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQEANTFG----TETFLATDEVHCVGH 668
Cdd:smart01008 1 TGEARYGDDIR-LPGMLHAAVVRSPVAHARIKSIDTSAARAMPGVVAVLTAKDVPGLNDFGplgpDEPVLADDKVRYVGQ 79
|
90 100
....*....|....*....|....*..
gi 110347467 669 LVCAVIADSETRAKQAAKQVKVVYQDL 695
Cdd:smart01008 80 PVAAVVAETEEAARDAAEAVKVEYEEL 106
|
|
| Fer2_2 |
pfam01799 |
[2Fe-2S] binding domain; |
87-160 |
1.00e-35 |
|
[2Fe-2S] binding domain;
Pssm-ID: 460336 [Multi-domain] Cd Length: 73 Bit Score: 129.86 E-value: 1.00e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 110347467 87 TVEGLGNTRTrlHPIQERIAKCHGTQCGFCTPGMVMSMYALL-RNHPEPTLDQLTDALGGNLCRCTGYRPIIDAC 160
Cdd:pfam01799 1 TIEGLAESGG--EPVQQAFAEAGAVQCGYCTPGMIMSAYALLeRNPPPPTEAEIREALSGNLCRCTGYRRIVDAV 73
|
|
| CutB |
COG1319 |
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion] ... |
241-518 |
7.28e-33 |
|
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 440930 [Multi-domain] Cd Length: 285 Bit Score: 129.47 E-value: 7.28e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 241 TWISPVTLKELVEAKFKY-PQAPIVMGYTSVGPEVKFkGVFHP---IIISpdRIEELGVISQARDGLTLGAGLSLDqvkD 316
Cdd:COG1319 5 EYHRPTSLEEALALLAEHgPDARVLAGGTDLLPLMKL-RLARPehlVDIN--RIPELRGIEEEGGGLRIGALVTHA---E 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 317 ILAD-IVQKLpeektqtYRALLKHLRTLAGSQIRNMASLGGHIVsrHLD--SDLNPLLAVGNCTLNLLSKDGERRIPLsE 393
Cdd:COG1319 79 LAASpLVRER-------YPLLAEAARAIASPQIRNRGTIGGNLA--NADpaADLPPALLALDATVELAGPDGERTIPA-A 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 394 EFLRKCPEADLKPQEVLVSVNIPWSRKWEfVSAFRQ-AQRQQNALAIVNSGmrVLFREGGGVIEELSILYGGVGSTIISA 472
Cdd:COG1319 149 DFFLGPGETALEPGELITAVRLPAPPAGA-GSAYLKvGRRASDAIALVSVA--VALRLDGGTIRDARIALGGVAPTPWRA 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 110347467 473 KNSCQRLIGRPWNEGMLDTACRLVLDEVTLAASAPGGKvEFKRTLI 518
Cdd:COG1319 226 REAEAALAGKPLSEEAIEAAAEAAAAAADPIDDVRASA-EYRRHLA 270
|
|
| CO_deh_flav_C |
pfam03450 |
CO dehydrogenase flavoprotein C-terminal domain; |
425-529 |
2.73e-32 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 460921 [Multi-domain] Cd Length: 102 Bit Score: 121.13 E-value: 2.73e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 425 SAFRQAQRQQNALAIVNSGMRVLFreGGGVIEELSILYGGVGSTIISAKNSCQRLIGRPWNEGMLDTACRLVLDEVTLaA 504
Cdd:pfam03450 1 AAYKQAKRRDDDIAIVNAAFRVRL--DGGTVEDARIAFGGVAPTPIRATEAEAALIGKPWDEETLEAAAALLLEDLSP-L 77
|
90 100
....*....|....*....|....*
gi 110347467 505 SAPGGKVEFKRTLIISFLFKFYLEV 529
Cdd:pfam03450 78 SDPRGSAEYRRHLARSLLFRFLLEA 102
|
|
| glyceraldDH_gamma |
NF041020 |
glyceraldehyde dehydrogenase subunit gamma; |
10-161 |
1.29e-28 |
|
glyceraldehyde dehydrogenase subunit gamma;
Pssm-ID: 468949 [Multi-domain] Cd Length: 162 Bit Score: 112.97 E-value: 1.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 10 VNGqKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISrynpstkairHHPVNACLTPICSLHGTAVTTVE 89
Cdd:NF041020 15 VNG-VWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMN----------GKSVKSCTVLAVQADGAEITTIE 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 110347467 90 GLGnTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACK 161
Cdd:NF041020 84 GLS-KDGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVK 154
|
|
| 4hydroxCoAred |
TIGR03193 |
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ... |
6-162 |
1.11e-24 |
|
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.
Pssm-ID: 132237 [Multi-domain] Cd Length: 148 Bit Score: 101.49 E-value: 1.11e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 6 LLFYVNGqKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISrynpstkairHHPVNACLTPICSLHGTAV 85
Cdd:TIGR03193 2 LRLTVNG-RWREDAVADNMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVD----------GRPRLACSTLAHRVAGRKV 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 110347467 86 TTVEGLGnTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKT 162
Cdd:TIGR03193 71 ETVEGLA-TNGRLSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEA 146
|
|
| CO_deh_flav_C |
smart01092 |
CO dehydrogenase flavoprotein C-terminal domain; |
426-529 |
3.54e-24 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 215021 [Multi-domain] Cd Length: 102 Bit Score: 98.07 E-value: 3.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 426 AFRQAQRQQNALAIVNSGMRVLFRegGGVIEELSILYGGVGSTIISAKNSCQRLIGRPWNEGMLDTACRLVLDEVTLAAS 505
Cdd:smart01092 1 AYKKSRRRDGDIALVSAAVALTLD--GGRVTEARIALGGVAPTPKRAAEAEAALVGKPLTDEALARAAAAALAQDFTPLS 78
|
90 100
....*....|....*....|....
gi 110347467 506 APGGKVEFKRTLIISFLFKFYLEV 529
Cdd:smart01092 79 DMRASAEYRRQLAANLLRRALLEA 102
|
|
| pucE |
TIGR03198 |
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ... |
5-165 |
1.28e-23 |
|
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.
Pssm-ID: 132242 [Multi-domain] Cd Length: 151 Bit Score: 98.38 E-value: 1.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 5 QLLFYVNGQKVvEKNVDPEMMLLPYLRKNLRLTGTKYGCGgggcgactvmISRYNPSTKAIRHHPVNACLTPICSLHGTA 84
Cdd:TIGR03198 3 QFRFTVNGQAW-EVAAVPTTRLSDLLRKELQLTGTKVSCG----------IGRCGACSVLIDGKLANACLTMAYQADGHE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 85 VTTVEGLgnTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFC 164
Cdd:TIGR03198 72 ITTIEGI--AENELDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSACRIR 149
|
.
gi 110347467 165 K 165
Cdd:TIGR03198 150 R 150
|
|
| Se_dep_XDH |
TIGR03311 |
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ... |
8-166 |
2.02e-22 |
|
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 132354 [Multi-domain] Cd Length: 848 Bit Score: 104.54 E-value: 2.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 8 FYVNGQKVVeknVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISrynpsTKAIRhhpvnACLTPICSLHGTAVTT 87
Cdd:TIGR03311 3 FIVNGREVD---VNEEKKLLEFLREDLRLTGVKNGCGEGACGACTVIVN-----GKAVR-----ACRFTTAKLAGKEITT 69
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 110347467 88 VEGLGNTRTRLHPIQerIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCKA 166
Cdd:TIGR03311 70 VEGLTEREKDVYAWA--FAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAVRLAAKA 146
|
|
| PRK09971 |
PRK09971 |
xanthine dehydrogenase subunit XdhB; Provisional |
245-518 |
1.56e-21 |
|
xanthine dehydrogenase subunit XdhB; Provisional
Pssm-ID: 182175 [Multi-domain] Cd Length: 291 Bit Score: 96.65 E-value: 1.56e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 245 PVTLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDG-LTLGAGLSLDQVkdILADIVQ 323
Cdd:PRK09971 10 AATLEEAIELLADNPQAKLIAGGTDVLIQLHHHNDRYRHLVSIHNIAELRGITLAEDGsIRIGAATTFTQI--IEDPIIQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 324 K-LPeektqtyrALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLSKDGERRIPLSeEFLRKCPEA 402
Cdd:PRK09971 88 KhLP--------ALAEAAVSIGGPQIRNVATIGGNICNGATSADSAPPLFALDAKLEIHSPNGVRFVPIN-GFYTGPGKV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 403 DLKPQEVLVSVNIPwSRKWEFVSA--FRQAQRqqNALAIVNSGMRVLFREGGGVIEELSILYGGVGSTIISAKNSCQRLI 480
Cdd:PRK09971 159 SLEHDEILVAFIIP-PEPYEHAGGayIKYAMR--DAMDIATIGCAVLCRLDNGNFEDLRLAFGVAAPTPIRCQHAEQTAK 235
|
250 260 270
....*....|....*....|....*....|....*...
gi 110347467 481 GRPWNEGMLDTACRLVLDEVTLAASAPGGKvEFKRTLI 518
Cdd:PRK09971 236 GAPLNLETLEAIGELVLQDVAPRSSWRASK-EFRLHLI 272
|
|
| PRK11433 |
PRK11433 |
aldehyde oxidoreductase 2Fe-2S subunit; Provisional |
5-159 |
5.49e-18 |
|
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
Pssm-ID: 236910 [Multi-domain] Cd Length: 217 Bit Score: 84.05 E-value: 5.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 5 QLLFYVNGqKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISrynpstkairHHPVNACLTPICSLHGTA 84
Cdd:PRK11433 51 PVTLKVNG-KTEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVN----------GRRLNACLTLAVMHQGAE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 85 VTTVEGLGnTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLR-------NH--------PEPTLDQLTDALGGNLCR 149
Cdd:PRK11433 120 ITTIEGLG-SPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKeikdgipSHvtvdltaaPELTADEIRERMSGNICR 198
|
170
....*....|
gi 110347467 150 CTGYRPIIDA 159
Cdd:PRK11433 199 CGAYSNILEA 208
|
|
| PRK09908 |
PRK09908 |
xanthine dehydrogenase iron sulfur-binding subunit XdhC; |
70-165 |
6.19e-17 |
|
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
Pssm-ID: 182139 [Multi-domain] Cd Length: 159 Bit Score: 79.57 E-value: 6.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 70 VNACLTPICSLHGTAVTTVEGLGNTrTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALL---RNHPePTLDQLTDALGGN 146
Cdd:PRK09908 61 IDSCLYLAAWAEGKEIRTLEGEAKG-GKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLakpREKP-LTITEIRRGLAGN 138
|
90
....*....|....*....
gi 110347467 147 LCRCTGYRPIIDACKTFCK 165
Cdd:PRK09908 139 LCRCTGYQMIVNTVLDCEK 157
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
69-154 |
4.44e-06 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 51.37 E-value: 4.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 69 PVNACLTPICSLHGTAVTTVEGLGNTRtRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLC 148
Cdd:PRK09800 55 IVNASLLIAAQLEKADIRTAESLGKWN-ELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFS 133
|
....*.
gi 110347467 149 RCTGYR 154
Cdd:PRK09800 134 RDAGWQ 139
|
|
| LAL_C2 |
pfam18603 |
L-amino acid ligase C-terminal domain 2; l-amino-acid ligases (LALs; EC 6.3.2.28) were ... |
613-692 |
4.33e-03 |
|
L-amino acid ligase C-terminal domain 2; l-amino-acid ligases (LALs; EC 6.3.2.28) were discovered to be ATP-grasp superfamily enzymes that catalyze the formation of an alpha-peptide bond between two l-amino acids in an ATP-dependent manner. The members of this family share a common structural architecture that consists of three domains referred to as the A-domain, B-domain and C-domain. The C domain can be further divided into the C1-subdomain and the C2-subdomain. This entry represents the C2 subdomain.
Pssm-ID: 436613 Cd Length: 78 Bit Score: 37.54 E-value: 4.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110347467 613 FVTSSRAhAKIVSID-LSEALSLPGVVDI-ITA---DHLQEantfgtetflATDEVHCVGHlvcaVIADSET------RA 681
Cdd:pfam18603 2 FLTAPRP-GRLRAVEgLEEARALPGVVEVeITVkpgDRVRP----------PRSSGDRLGY----VIATGDTpeealaAA 66
|
90
....*....|.
gi 110347467 682 KQAAKQVKVVY 692
Cdd:pfam18603 67 EAAAALIRIEV 77
|
|
| |
