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Conserved domains on  [gi|38045954|ref|NP_008889|]
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zinc finger protein 16 isoform 1 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
303-675 3.58e-14

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 75.50  E-value: 3.58e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 303 SQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVCS--ECGKAFRRSSNLIKHHRTHTGEKPFECg 380
Cdd:COG5048  16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLN- 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 381 ecgkafSQSAHLRKHQRVHTGE--------KPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDC---GKAFSQSSSLI 449
Cdd:COG5048  95 ------SKSLPLSNSKASSSSLsssssnsnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnssSVNTPQSNSLH 168

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 450 QHRRIHtgekphvcNVCGKAFSYSSVLRKHQIIHTGEKPYRCSvCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRS 529
Cdd:COG5048 169 PPLPAN--------SLSKDPSSNLSLLISSNVSTSIPSSSENS-PLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKS 239

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 530 SNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNG-------LKPHECNQCGKAFNRSSNLIHHQ--KVHTGE-- 598
Cdd:COG5048 240 LLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEsl 319

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 599 KPYTCVE--CGKGFSQSSHLIQHQIIHTGERPYKC--SECGKAFSQRSV-----LIQHQRIHTGVKPYDCA--ACGKAFS 667
Cdd:COG5048 320 KPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFK 399


                ....*...
gi 38045954 668 QRSKLIKH 675
Cdd:COG5048 400 RDSNLSLH 407
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
160-369 1.60e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 1.60e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 160 SRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHSVDLTGHEGvptAESPLICNECGKTFQGNPDL--IQRQIVHTGEASF 237
Cdd:COG5048 244 SPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKG---FSLPIKSKQCNISFSRSSPLtrHLRSVNHSGESLK 320

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 238 MCD----DCGKTFSQNSVLKNRHRSHMSEKAYQC--SECGKAFRGHSDFSRHQSHH-----SSERPYMC--NECGKAFSQ 304
Cdd:COG5048 321 PFScpysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKR 400

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38045954 305 NSSLKKHQKSHMSEKPYECN--ECGKAFRRSSNLIQHQRIHSgEKPYVCSECGKAFRRSSNLIKHHR 369
Cdd:COG5048 401 DSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT-NHAPLLCSILKSFRRDLDLSNHGK 466
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
303-675 3.58e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 75.50  E-value: 3.58e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 303 SQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVCS--ECGKAFRRSSNLIKHHRTHTGEKPFECg 380
Cdd:COG5048  16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLN- 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 381 ecgkafSQSAHLRKHQRVHTGE--------KPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDC---GKAFSQSSSLI 449
Cdd:COG5048  95 ------SKSLPLSNSKASSSSLsssssnsnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnssSVNTPQSNSLH 168

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 450 QHRRIHtgekphvcNVCGKAFSYSSVLRKHQIIHTGEKPYRCSvCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRS 529
Cdd:COG5048 169 PPLPAN--------SLSKDPSSNLSLLISSNVSTSIPSSSENS-PLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKS 239

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 530 SNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNG-------LKPHECNQCGKAFNRSSNLIHHQ--KVHTGE-- 598
Cdd:COG5048 240 LLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEsl 319

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 599 KPYTCVE--CGKGFSQSSHLIQHQIIHTGERPYKC--SECGKAFSQRSV-----LIQHQRIHTGVKPYDCA--ACGKAFS 667
Cdd:COG5048 320 KPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFK 399


                ....*...
gi 38045954 668 QRSKLIKH 675
Cdd:COG5048 400 RDSNLSLH 407
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
160-369 1.60e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 1.60e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 160 SRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHSVDLTGHEGvptAESPLICNECGKTFQGNPDL--IQRQIVHTGEASF 237
Cdd:COG5048 244 SPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKG---FSLPIKSKQCNISFSRSSPLtrHLRSVNHSGESLK 320

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 238 MCD----DCGKTFSQNSVLKNRHRSHMSEKAYQC--SECGKAFRGHSDFSRHQSHH-----SSERPYMC--NECGKAFSQ 304
Cdd:COG5048 321 PFScpysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKR 400

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38045954 305 NSSLKKHQKSHMSEKPYECN--ECGKAFRRSSNLIQHQRIHSgEKPYVCSECGKAFRRSSNLIKHHR 369
Cdd:COG5048 401 DSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT-NHAPLLCSILKSFRRDLDLSNHGK 466
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 543-595 1.88e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 1.88e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 38045954 543 KPYeCTECGKTFSQSSTLIQHQRIHnglkpH-ECNQCGKAFNRSSNL-IHHQKVH 595
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAK-----HfKCHICHKKLYTAGGLaVHCLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
476-500 3.07e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.07e-04
                          10        20
                  ....*....|....*....|....*
gi 38045954   476 LRKHQIIHTGEKPYRCSVCGKAFSH 500
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 432-481 5.23e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 37.55  E-value: 5.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 38045954  432 PYKCSDCGKAFSQSSSLIQHRRIHTGEKphVCNVCGKAFSYSS-----VLRKHQI 481
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDstldhVCKKHNI 125
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
303-675 3.58e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 75.50  E-value: 3.58e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 303 SQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVCS--ECGKAFRRSSNLIKHHRTHTGEKPFECg 380
Cdd:COG5048  16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLN- 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 381 ecgkafSQSAHLRKHQRVHTGE--------KPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDC---GKAFSQSSSLI 449
Cdd:COG5048  95 ------SKSLPLSNSKASSSSLsssssnsnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnssSVNTPQSNSLH 168

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 450 QHRRIHtgekphvcNVCGKAFSYSSVLRKHQIIHTGEKPYRCSvCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRS 529
Cdd:COG5048 169 PPLPAN--------SLSKDPSSNLSLLISSNVSTSIPSSSENS-PLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKS 239

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 530 SNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNG-------LKPHECNQCGKAFNRSSNLIHHQ--KVHTGE-- 598
Cdd:COG5048 240 LLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEsl 319

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 599 KPYTCVE--CGKGFSQSSHLIQHQIIHTGERPYKC--SECGKAFSQRSV-----LIQHQRIHTGVKPYDCA--ACGKAFS 667
Cdd:COG5048 320 KPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFK 399


                ....*...
gi 38045954 668 QRSKLIKH 675
Cdd:COG5048 400 RDSNLSLH 407
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
291-642 4.81e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.65  E-value: 4.81e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 291 RPYMCNECGKAFSQNSSLKKHQKSHMSEKPYECN--ECGKAFRRSSNLIQHQRIHSGEKPYVCS---------------- 352
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkslplsnskassssls 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 353 ECGKAFRR----SSNLIKHHRTHTGEKPFE------------CGECGKAFSQSAHLR-------------------KHQR 397
Cdd:COG5048 112 SSSSNSNDnnllSSHSLPPSSRDPQLPDLLsisnlrnnplpgNNSSSVNTPQSNSLHpplpanslskdpssnlsllISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 398 VHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAFSYSSVLR 477
Cdd:COG5048 192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 478 KHQIIHTGE-------KPYRCSVCGKAFSHSSALIQHQ--GVHTG--DKPYACHE--CGKTFGRSSNLILHQRVHTGEKP 544
Cdd:COG5048 272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 545 YEC--TECGKTFSQSST-----LIQHQRIHNGLKPHEC--NQCGKAFNRSSNLIHHQKVHTGEKP--YTCVECGKGFSQS 613
Cdd:COG5048 352 AKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                       410       420
                ....*....|....*....|....*....
gi 38045954 614 SHLIQHQIIHTGERPYKCSECGKAFSQRS 642
Cdd:COG5048 432 YNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
230-471 3.27e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.87  E-value: 3.27e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 230 VHTGEASFMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRHQS-HHSSERPYMCNECGKAFSQNSSL 308
Cdd:COG5048 192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSlSSSDSSSSASESPRSSLPTASSQ 271

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 309 KKHQKSHMSEK------PYECNECGKAFRRSSNLIQHQR--IHSGE--KPYVCSE--CGKAFRRSSNLIKHHRTHTGEKP 376
Cdd:COG5048 272 SSSPNESDSSSekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 377 FEC--GECGKAFSQSAHLRKHQRVH-----TGEKPYEC--NDCGKPFSRVSNLIKHHRVHTGEKP--YKCSDCGKAFSQS 445
Cdd:COG5048 352 AKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                       250       260
                ....*....|....*....|....*.
gi 38045954 446 SSLIQHRRIHTGEKPHVCNVCGKAFS 471
Cdd:COG5048 432 YNLIPHKKIHTNHAPLLCSILKSFRR 457
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
160-369 1.60e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 1.60e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 160 SRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHSVDLTGHEGvptAESPLICNECGKTFQGNPDL--IQRQIVHTGEASF 237
Cdd:COG5048 244 SPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKG---FSLPIKSKQCNISFSRSSPLtrHLRSVNHSGESLK 320

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 238 MCD----DCGKTFSQNSVLKNRHRSHMSEKAYQC--SECGKAFRGHSDFSRHQSHH-----SSERPYMC--NECGKAFSQ 304
Cdd:COG5048 321 PFScpysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETlsNSCIRNFKR 400

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38045954 305 NSSLKKHQKSHMSEKPYECN--ECGKAFRRSSNLIQHQRIHSgEKPYVCSECGKAFRRSSNLIKHHR 369
Cdd:COG5048 401 DSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT-NHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 290-372 8.71e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.48  E-value: 8.71e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 290 ERPYMCN--ECGKAFSQNSSLKKHQK-SHMSEKPYEcnecgkafrrSSNLIQHQRIHSGEKPYVCSECGKAFrRSSNLIK 366
Cdd:COG5189 347 GKPYKCPveGCNKKYKNQNGLKYHMLhGHQNQKLHE----------NPSPEKMNIFSAKDKPYRCEVCDKRY-KNLNGLK 415


                ....*.
gi 38045954 367 HHRTHT 372
Cdd:COG5189 416 YHRKHS 421
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 429-509 1.36e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.71  E-value: 1.36e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38045954 429 GEKPYKCS--DCGKAFSQSSSLIQHRRihtgeKPHvcnvCGKAFSYSSVLRKHQIIHTGEKPYRCSVCGKAFSHSSALIQ 506
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHML-----HGH----QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                ...
gi 38045954 507 HQG 509
Cdd:COG5189 417 HRK 419
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 543-595 1.88e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 1.88e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 38045954 543 KPYeCTECGKTFSQSSTLIQHQRIHnglkpH-ECNQCGKAFNRSSNL-IHHQKVH 595
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAK-----HfKCHICHKKLYTAGGLaVHCLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
476-500 3.07e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.07e-04
                          10        20
                  ....*....|....*....|....*
gi 38045954   476 LRKHQIIHTGEKPYRCSVCGKAFSH 500
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
335-360 4.92e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 4.92e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   335 NLIQHQRIHSGEKPYVCSECGKAFRR 360
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
615-640 5.26e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 5.26e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   615 HLIQHQIIHTGERPYKCSECGKAFSQ 640
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
363-388 5.64e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 5.64e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   363 NLIKHHRTHTGEKPFECGECGKAFSQ 388
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
419-444 5.69e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 5.69e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   419 NLIKHHRVHTGEKPYKCSDCGKAFSQ 444
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
531-556 6.04e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 6.04e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   531 NLILHQRVHTGEKPYECTECGKTFSQ 556
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 349-371 6.71e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 37.28  E-value: 6.71e-04
                          10        20
                  ....*....|....*....|...
gi 38045954   349 YVCSECGKAFRRSSNLIKHHRTH 371
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
307-332 7.72e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 7.72e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   307 SLKKHQKSHMSEKPYECNECGKAFRR 332
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
447-472 8.52e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 8.52e-04
                          10        20
                  ....*....|....*....|....*.
gi 38045954   447 SLIQHRRIHTGEKPHVCNVCGKAFSY 472
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 321-343 9.09e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.89  E-value: 9.09e-04
                          10        20
                  ....*....|....*....|...
gi 38045954   321 YECNECGKAFRRSSNLIQHQRIH 343
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
391-416 2.08e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.08e-03
                          10        20
                  ....*....|....*....|....*.
gi 38045954   391 HLRKHQRVHTGEKPYECNDCGKPFSR 416
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 293-315 2.40e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 2.40e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   293 YMCNECGKAFSQNSSLKKHQKSH 315
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 433-455 2.55e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 2.55e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   433 YKCSDCGKAFSQSSSLIQHRRIH 455
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 545-567 2.55e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 2.55e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   545 YECTECGKTFSQSSTLIQHQRIH 567
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 377-399 2.92e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 2.92e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   377 FECGECGKAFSQSAHLRKHQRVH 399
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 405-427 3.42e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 3.42e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   405 YECNDCGKPFSRVSNLIKHHRVH 427
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
PHA00733 PHA00733
hypothetical protein
 432-481 5.23e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 37.55  E-value: 5.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 38045954  432 PYKCSDCGKAFSQSSSLIQHRRIHTGEKphVCNVCGKAFSYSS-----VLRKHQI 481
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDstldhVCKKHNI 125
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 517-539 5.32e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 5.32e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   517 YACHECGKTFGRSSNLILHQRVH 539
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
644-668 5.40e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 5.40e-03
                          10        20
                  ....*....|....*....|....*
gi 38045954   644 LIQHQRIHTGVKPYDCAACGKAFSQ 668
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 573-595 5.98e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.58  E-value: 5.98e-03
                          10        20
                  ....*....|....*....|...
gi 38045954   573 HECNQCGKAFNRSSNLIHHQKVH 595
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 487-539 6.41e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.00  E-value: 6.41e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 38045954 487 KPYrCSVCGKAFSHSSALIQHQGVHTgdkpYACHECGKTFGRSSNLILH-QRVH 539
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHcLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
560-584 8.82e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 8.82e-03
                          10        20
                  ....*....|....*....|....*
gi 38045954   560 LIQHQRIHNGLKPHECNQCGKAFNR 584
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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