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Conserved domains on  [gi|170016081|ref|NP_008846|]
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protein XRP2 [Homo sapiens]

Protein Classification

TBCC domain-containing protein( domain architecture ID 11172638)

TBCC (Tubulin binding cofactor C) domain-containing protein such as human retinitis pigmentosa protein 2 (Rp2), a GTPase-activating protein for Arf-like 3 and human TBCC-domain containing 1 (TBCCD1), a centrosomal protein required for centrosome and Golgi apparatus positioning

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TBCC pfam07986
Tubulin binding cofactor C; Members of this family are involved in the folding pathway of ...
 59-177 3.36e-58

Tubulin binding cofactor C; Members of this family are involved in the folding pathway of tubulins and form a beta helix structure.


:

Pssm-ID: 462331  Cd Length: 119  Bit Score: 183.95  E-value: 3.36e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170016081   59 GQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIE 138
Cdd:pfam07986   1 GVDVKLSNLSNCTIYLLDPLSSVTIDDCKNCTIFLGPVSGSVFIRDCENCTIVVACRQLRIHDCTNCDFYLHTTSRPIIE 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 170016081  139 SSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDF 177
Cdd:pfam07986  81 DSTGIRFAPYNTSYPGLEEHLKSAGLDPENNNWSQVDDF 119
 
Name Accession Description Interval E-value
TBCC pfam07986
Tubulin binding cofactor C; Members of this family are involved in the folding pathway of ...
 59-177 3.36e-58

Tubulin binding cofactor C; Members of this family are involved in the folding pathway of tubulins and form a beta helix structure.


Pssm-ID: 462331  Cd Length: 119  Bit Score: 183.95  E-value: 3.36e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170016081   59 GQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIE 138
Cdd:pfam07986   1 GVDVKLSNLSNCTIYLLDPLSSVTIDDCKNCTIFLGPVSGSVFIRDCENCTIVVACRQLRIHDCTNCDFYLHTTSRPIIE 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 170016081  139 SSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDF 177
Cdd:pfam07986  81 DSTGIRFAPYNTSYPGLEEHLKSAGLDPENNNWSQVDDF 119
CARP smart00673
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product;
67-104 6.42e-09

Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product;


Pssm-ID: 197827  Cd Length: 38  Bit Score: 50.98  E-value: 6.42e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 170016081    67 CENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRN 104
Cdd:smart00673   1 CESCTIQVSGKVNTISIDKCKKCSIYLGPVSGSPEIVN 38
 
Name Accession Description Interval E-value
TBCC pfam07986
Tubulin binding cofactor C; Members of this family are involved in the folding pathway of ...
 59-177 3.36e-58

Tubulin binding cofactor C; Members of this family are involved in the folding pathway of tubulins and form a beta helix structure.


Pssm-ID: 462331  Cd Length: 119  Bit Score: 183.95  E-value: 3.36e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170016081   59 GQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIE 138
Cdd:pfam07986   1 GVDVKLSNLSNCTIYLLDPLSSVTIDDCKNCTIFLGPVSGSVFIRDCENCTIVVACRQLRIHDCTNCDFYLHTTSRPIIE 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 170016081  139 SSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDF 177
Cdd:pfam07986  81 DSTGIRFAPYNTSYPGLEEHLKSAGLDPENNNWSQVDDF 119
CARP smart00673
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product;
67-104 6.42e-09

Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product;


Pssm-ID: 197827  Cd Length: 38  Bit Score: 50.98  E-value: 6.42e-09
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 170016081    67 CENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRN 104
Cdd:smart00673   1 CESCTIQVSGKVNTISIDKCKKCSIYLGPVSGSPEIVN 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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