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Conserved domains on  [gi|5453567|ref|NP_006315|]
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craniofacial development protein 1 [Homo sapiens]

Protein Classification

BCNT domain-containing protein( domain architecture ID 10540970)

BCNT domain-containing protein similar to human craniofacial development protein 1 (CFDP1), also called Bucentaur (BCNT), that may play a role during embryogenesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BCNT pfam07572
Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) ...
 225-295 3.79e-29

Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) in ruminents has a different domain architecture to that in mouse and human. For this reason it has been used as a model for molecular evolution. Both bovine and human BCNTs are phosphorylated by casein kinase II in vitro.


:

Pssm-ID: 462213  Cd Length: 71  Bit Score: 106.14  E-value: 3.79e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 5453567    225 SSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLS 295
Cdd:pfam07572   1 DSILAALGAKKKKLSTLEKSKLDWASFKDKEGIEEELELHNKGKDGYLEKQDFLQRVDLRRFEIEREARLA 71
 
Name Accession Description Interval E-value
BCNT pfam07572
Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) ...
 225-295 3.79e-29

Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) in ruminents has a different domain architecture to that in mouse and human. For this reason it has been used as a model for molecular evolution. Both bovine and human BCNTs are phosphorylated by casein kinase II in vitro.


Pssm-ID: 462213  Cd Length: 71  Bit Score: 106.14  E-value: 3.79e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 5453567    225 SSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLS 295
Cdd:pfam07572   1 DSILAALGAKKKKLSTLEKSKLDWASFKDKEGIEEELELHNKGKDGYLEKQDFLQRVDLRRFEIEREARLA 71
 
Name Accession Description Interval E-value
BCNT pfam07572
Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) ...
 225-295 3.79e-29

Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) in ruminents has a different domain architecture to that in mouse and human. For this reason it has been used as a model for molecular evolution. Both bovine and human BCNTs are phosphorylated by casein kinase II in vitro.


Pssm-ID: 462213  Cd Length: 71  Bit Score: 106.14  E-value: 3.79e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 5453567    225 SSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLS 295
Cdd:pfam07572   1 DSILAALGAKKKKLSTLEKSKLDWASFKDKEGIEEELELHNKGKDGYLEKQDFLQRVDLRRFEIEREARLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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