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Conserved domains on  [gi|42542379|ref|NP_005830|]
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serine/arginine repetitive matrix protein 1 isoform 2 [Homo sapiens]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.79e-38

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.79e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379    46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 606-740 3.88e-07

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 54.41  E-value: 3.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 685
Cdd:PHA03307  275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 42542379   686 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Cdd:PHA03307  351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.79e-38

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.79e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379    46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PWI smart00311
PWI, domain in splicing factors;
40-115 1.95e-28

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 108.97  E-value: 1.95e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42542379     40 MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLngkNAREFMGELWPLLLSAQEN 115
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQhKGPQAKLLQINLTGFE---DAEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 606-740 3.88e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 54.41  E-value: 3.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 685
Cdd:PHA03307  275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 42542379   686 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Cdd:PHA03307  351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
Retinal pfam15449
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. ...
 606-720 9.35e-05

Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.


Pssm-ID: 464722 [Multi-domain]  Cd Length: 1293  Bit Score: 46.31  E-value: 9.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379    606 PSPPPKRRTASPPPPPKRrasPSPPPkrrVSHSPPPKQRSSPVTKRRSPSLSSkhrkGSSPSRSTREARSPQPNkRHSPS 685
Cdd:pfam15449 1072 LSPPTSKKRTSPPPQHKL---PSPPP---ESPPAQHKLSSPPTQRTEASSPSS----GPSPSPPTSPSQGHKET-RDSED 1140

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 42542379    686 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
Cdd:pfam15449 1141 SQAATAKASGNTCSIFCPATSSLFEAKSPFSTAHP 1175
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.79e-38

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.79e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379    46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PWI smart00311
PWI, domain in splicing factors;
40-115 1.95e-28

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 108.97  E-value: 1.95e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42542379     40 MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLngkNAREFMGELWPLLLSAQEN 115
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQhKGPQAKLLQINLTGFE---DAEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 606-740 3.88e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 54.41  E-value: 3.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 685
Cdd:PHA03307  275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 42542379   686 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Cdd:PHA03307  351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PHA03247 PHA03247
large tegument protein UL36; Provisional
 605-730 2.74e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.48  E-value: 2.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   605 SPSPPPKRRTASPPPPPKRRASPSPP------PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRkgSSPSRSTREARSPQP 678
Cdd:PHA03247 2826 GPLPPPTSAQPTAPPPPPGPPPPSLPlggsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR--PAVSRSTESFALPPD 2903

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 42542379   679 NKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
Cdd:PHA03247 2904 QPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEP 2955
PHA03247 PHA03247
large tegument protein UL36; Provisional
 591-785 1.47e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 1.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   591 PSPRRYSPPIQ------------RRYSPSPPPK----RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654
Cdd:PHA03247 2562 AAPDRSVPPPRpaprpsepavtsRARRPDAPPQsarpRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPH 2641

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   655 SLSS-----KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729
Cdd:PHA03247 2642 PPPTvpppeRPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPL 2721

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 42542379   730 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPspvqsQSPSTNWSPAVP 785
Cdd:PHA03247 2722 PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP-----PTTAGPPAPAPP 2772
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 603-729 1.77e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 48.56  E-value: 1.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSSPVTkrrSPSLSSKHRKGSSPSRSTREARSPQPN 679
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 42542379  680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 609-740 3.35e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.86  E-value: 3.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSpqpnkrhSPSPRP 688
Cdd:PHA03307  266 PTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSS-------SESSRG 338

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42542379   689 RA---------PQTSSSPPPVRRGasSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Cdd:PHA03307  339 AAvspgpspsrSPSPSRPPPPADP--SSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGR 397
PHA03247 PHA03247
large tegument protein UL36; Provisional
 605-785 3.52e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 3.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   685 SPRPRAPQTSSSPPPV---------------RRGASSSPqrrqSPSPSTRPIRRVSRTPEPKKIKKAAS-PSPQSVRRVS 748
Cdd:PHA03247 2833 SAQPTAPPPPPGPPPPslplggsvapggdvrRRPPSRSP----AAKPAAPARPPVRRLARPAVSRSTESfALPPDQPERP 2908

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 42542379   749 SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
Cdd:PHA03247 2909 PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAP 2945
Retinal pfam15449
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. ...
 606-720 9.35e-05

Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.


Pssm-ID: 464722 [Multi-domain]  Cd Length: 1293  Bit Score: 46.31  E-value: 9.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379    606 PSPPPKRRTASPPPPPKRrasPSPPPkrrVSHSPPPKQRSSPVTKRRSPSLSSkhrkGSSPSRSTREARSPQPNkRHSPS 685
Cdd:pfam15449 1072 LSPPTSKKRTSPPPQHKL---PSPPP---ESPPAQHKLSSPPTQRTEASSPSS----GPSPSPPTSPSQGHKET-RDSED 1140

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 42542379    686 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
Cdd:pfam15449 1141 SQAATAKASGNTCSIFCPATSSLFEAKSPFSTAHP 1175
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
608-742 1.18e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 45.42  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   608 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRhSPSPR 687
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQR-GPSGS 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 42542379   688 PRAPQTSSSPPPVRRGASSS-PQRRQSP-SPS-TRPIRRVSRTPEPKKIKKAASPSPQ 742
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEhTQRRKTPpATSnRRSPHSTATPPPTTKRQETGRPTPR 304
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 605-730 1.46e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 1.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Cdd:PRK07764 620 APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA 699

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 42542379  685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
Cdd:PRK07764 700 QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 609-741 1.59e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.45  E-value: 1.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  609 PPKRRTASPPPP--------PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSlsSKHRKGSSPSRSTR-----EARS 675
Cdd:PTZ00449 510 PPEGPEASGLPPkapgdkegEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPA--KEHKPSKIPTLSKKpefpkDPKH 587

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42542379  676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASS----SPQRRQSPS------PSTRPI--RRVSRTPEPKKIKKAASPSP 741
Cdd:PTZ00449 588 PKDPEEPKKPKRPRSAQRPTRPKSPKLPELLdipkSPKRPESPKspkrppPPQRPSspERPEGPKIIKSPKPPKSPKP 665
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 605-740 2.09e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 45.10  E-value: 2.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  605 SPSPPPKRRTASPPpppkRRASPSPPPKRRVSHSPPPKQRSSPVTKRRsPSLSskhrKGSSPSRSTREARSPQPNKRHSP 684
Cdd:PHA03269  24 TNIPIPELHTSAAT----QKPDPAPAPHQAASRAPDPAVAPTSAASRK-PDLA----QAPTPAASEKFDPAPAPHQAASR 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 42542379  685 SPRPR-APQTSSSPPPVRRGA-SSSPQRRqsPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Cdd:PHA03269  95 APDPAvAPQLAAAPKPDAAEAfTSAAQAH--EAPADAGTSAASKKPDPAAHTQHSPPP 150
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 604-702 2.32e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 45.06  E-value: 2.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   604 YSPSPPpkrRTASPPPPPKRRASPSPppKRRVSHSPPPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683
Cdd:pfam10486 393 SSSSSP---RAEKPREKSKKKSRSRL--SQRIYRLFKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRS 464

                          90
                  ....*....|....*....
gi 42542379   684 PSPRPRAPQTSSSPPPVRR 702
Cdd:pfam10486 465 LEPPPLPPLSALRHVCFRR 483
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
606-783 2.58e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.87  E-value: 2.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  606 PSPPPKRRTASPPPPPKRRASPSPPPKrrvSHSPPPKQRSSPvtKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS 685
Cdd:PRK12323 385 PAPAAAAPAAAAPAPAAPPAAPAAAPA---AAAAARAVAAAP--ARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPA 459

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  686 PRPRAPQTSSSPPPVrrgASSSPQRRQSPSPSTRPIRRV----SRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 761
Cdd:PRK12323 460 AAARPAAAGPRPVAA---AAAAAPARAAPAAAPAPADDDpppwEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDD 536

                        170       180
                 ....*....|....*....|..
gi 42542379  762 KKPPAPPSPVQSQSPSTNWSPA 783
Cdd:PRK12323 537 AFETLAPAPAAAPAPRAAAATE 558
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 605-705 3.59e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 3.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK--QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682
Cdd:PRK07764 409 APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGnaPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAP 488

                         90       100
                 ....*....|....*....|...
gi 42542379  683 SPSPRPRAPQTSSSPPPVRRGAS 705
Cdd:PRK07764 489 APAAAPAAPAAPAAPAGADDAAT 511
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 603-720 4.33e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 4.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682
Cdd:PRK07764 585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 42542379  683 SPSPRP---RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
Cdd:PRK07764 665 GGDGWPakaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 621-741 5.00e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 5.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
Cdd:PHA03307  256 PLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSES 335

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 42542379   701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741
Cdd:PHA03307  336 SRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPS 376
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 605-720 5.17e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 5.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   605 SPSPPPKRRTASPPPPPkrRASPSPPPKRRVSHSPPPKQRSSPvtkrrspslsskhrkGSSPSRSTREARSPQPNKRHSP 684
Cdd:PHA03307  342 SPGPSPSRSPSPSRPPP--PADPSSPRKRPRPSRAPSSPAASA---------------GRPTRRRARAAVAGRARRRDAT 404

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 42542379   685 SPRPRApQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
Cdd:PHA03307  405 GRFPAG-RPRPSPLDAGAASGAFYARYPLLTPSGEP 439
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 602-742 6.29e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 6.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   602 RRYSPSPPPKRRTASPPPPPKRRA-------SPSPPPKRRVSHSPPPK--QRSSPVTKRRSPSLSSKHRKGSSPSRSTRE 672
Cdd:PHA03307   82 NESRSTPTWSLSTLAPASPAREGSptppgpsSPDPPPPTPPPASPPPSpaPDLSEMLRPVGSPGPPPAASPPAAGASPAA 161

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 42542379   673 ARSPQPNKRHSPSPRPRAPQTS---SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742
Cdd:PHA03307  162 VASDAASSRQAALPLSSPEETArapSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGA 234
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 601-731 9.13e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 9.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   601 QRRYSPSPPPKRRTASPPPPPKRRASPSPP------PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA- 673
Cdd:PHA03307  781 QRGAGSSPPVRAEAAFRRPGRLRRSGPAADaasrtaSKRKSRSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAa 860

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42542379   674 ---RSPQPNKRHSPSPRPRAPQTSSSPPPV---RRGASSSPQRRQSPSPSTRPIRRVSRTPEPK 731
Cdd:PHA03307  861 aggRARGKNGRRRPRPPEPRARPGAAAPPKaaaAAPPAGAPAPRPRPAPRVKLGPMPPGGPDPR 924
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
605-718 1.08e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 1.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  605 SPSPPPKRRTASPPPPPKRRASPSPPPKR-------RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
Cdd:PRK12323 455 AAAPAAAARPAAAGPRPVAAAAAAAPARAapaaapaPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADP 534

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 42542379  678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718
Cdd:PRK12323 535 DDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 605-783 1.27e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.85  E-value: 1.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRV-SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683
Cdd:PHA03307  132 PDLSEMLRPVGSPGPPPAASPPAAGASPAAVaSDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSS 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   684 P------SPRPRAPQTSSSPPPVRRGASSSPQRRQS----------PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRV 747
Cdd:PHA03307  212 PisasasSPAPAPGRSAADDAGASSSDSSSSESSGCgwgpenecplPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSP 291

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 42542379   748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPA 783
Cdd:PHA03307  292 RERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSS 327
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 630-787 1.39e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  630 PPKRRVSHSPPPKQ--RSSPVTKRRSPSLSSKHRKGSSPSRSTREA---RSPQPNKRHSPSP------RPRAPQTSSSPp 698
Cdd:PTZ00449 510 PPEGPEASGLPPKApgDKEGEEGEHEDSKESDEPKEGGKPGETKEGevgKKPGPAKEHKPSKiptlskKPEFPKDPKHP- 588

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  699 pvRRgaSSSPQRRQSPSPSTRPIRRVS-RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
Cdd:PTZ00449 589 --KD--PEEPKKPKRPRSAQRPTRPKSpKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPK 664

                        170
                 ....*....|
gi 42542379  778 TNWSPAVPVK 787
Cdd:PTZ00449 665 PPFDPKFKEK 674
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 605-709 1.40e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Cdd:PRK07764 399 PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTA 478

                         90       100
                 ....*....|....*....|....*
gi 42542379  685 SPRPRAPQTSSSPPPVRRGASSSPQ 709
Cdd:PRK07764 479 APAPAPPAAPAPAAAPAAPAAPAAP 503
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 606-722 1.86e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSlSSKHRKGSSPSRSTREARSPQPNKRHSPS 685
Cdd:PRK07764 672 KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQP-PQAAQGASAPSPAADDPVPLPPEPDDPPD 750

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 42542379  686 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIR 722
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
Gag_spuma pfam03276
Spumavirus gag protein;
606-715 3.38e-03

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 41.27  E-value: 3.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379   606 PSPPPKRRTASPPPPPK-------RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSpslSSKHRKGSSPSRSTREARSPQP 678
Cdd:pfam03276 207 PAIPGIHARAPPGNIARslgddimPSLGDAGMPQPRFAFHPGNPFAEAEGHPFAE---AEGERPRDIPRAPRIDAPSAPA 283

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 42542379   679 NKRHSPSPRPrAPQTSSSPPPVRRGASSSPQRRQSPS 715
Cdd:pfam03276 284 IPAIQPIAPP-MIPPIGAPIPIPHGASIPGEHIRNPR 319
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 611-730 3.41e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 3.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42542379  611 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS---KHRKGSSPSRSTREARSPQPNKRHsPSPR 687
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASapaAPPAAAPPAPVAAPAAAAPAAAPA-AAPA 443

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 42542379  688 PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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