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Conserved domains on  [gi|1812229404|ref|NP_004804|]
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peroxisomal biogenesis factor 16 isoform 1 [Homo sapiens]

Protein Classification

peroxisomal membrane protein PEX16( domain architecture ID 10554343)

peroxisomal membrane protein PEX16 is required for peroxisome membrane biogenesis, and may play a role in the early stages of peroxisome assembly

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Pex16 pfam08610
Peroxisomal membrane protein (Pex16); Pex16 is a peripheral protein located at the matrix face ...
10-329 7.93e-108

Peroxisomal membrane protein (Pex16); Pex16 is a peripheral protein located at the matrix face of the peroxisomal membrane.


:

Pssm-ID: 462535  Cd Length: 347  Bit Score: 318.46  E-value: 7.93e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404  10 RYQEYVTRHPAATAQLETAVRGFSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKL---------PVSLSQQ 80
Cdd:pfam08610   2 AYEKFVRKNPSAVSQIESTLRSLTYLLPGRFRDSEIASELLYSLLNLLSLYNDSILSRAVKSPPhtrytrfwtKKSPLYR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404  81 KLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALVQLAKAVLRMLLLLWFKAGLQTSPPIvPLDRETQAQP------PD 154
Cdd:pfam08610  82 RLARLLTVLEYTELLLEMAARRLWGEKGRWRVIVLIEAIKAVLRLLLLRLTKSRPLLSPPI-PPNREKLLDPeelpqeEL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404 155 GDHSPGNHEQSYVGKRSNRVVRTLQN--TPSLHSRHWGAPQQREGRQQQHH------EELSATPTPLGLQETIAEFLYIA 226
Cdd:pfam08610 161 KDDPSSSGSESWTLPRTGRVLPSLPSsgSPSLQTRTWKPPPSSAEEISSYLlskvltADDIKPPTSLLGRLKGAEVLYIL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404 227 RPLLHLLSLGLWGQRSWKPWLLAGVVDVTSLSLLSDRKGLTRRERRELRRR-----TILLLYYLLRSPFYDRFSEARILF 301
Cdd:pfam08610 241 RPLIYLLALRRFGRRSWKPWLISLALELASRQLRSRGRGGTPRHLSALEREelkrrGLLLLLYLLRGPFYDNYTRPKIES 320
                         330       340
                  ....*....|....*....|....*...
gi 1812229404 302 lLQLLADHVPGVGLVTRPLMDYLPTWQK 329
Cdd:pfam08610 321 -LALLLEGVPLLGLVGGPLEDYLPLWQE 347
 
Name Accession Description Interval E-value
Pex16 pfam08610
Peroxisomal membrane protein (Pex16); Pex16 is a peripheral protein located at the matrix face ...
10-329 7.93e-108

Peroxisomal membrane protein (Pex16); Pex16 is a peripheral protein located at the matrix face of the peroxisomal membrane.


Pssm-ID: 462535  Cd Length: 347  Bit Score: 318.46  E-value: 7.93e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404  10 RYQEYVTRHPAATAQLETAVRGFSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKL---------PVSLSQQ 80
Cdd:pfam08610   2 AYEKFVRKNPSAVSQIESTLRSLTYLLPGRFRDSEIASELLYSLLNLLSLYNDSILSRAVKSPPhtrytrfwtKKSPLYR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404  81 KLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALVQLAKAVLRMLLLLWFKAGLQTSPPIvPLDRETQAQP------PD 154
Cdd:pfam08610  82 RLARLLTVLEYTELLLEMAARRLWGEKGRWRVIVLIEAIKAVLRLLLLRLTKSRPLLSPPI-PPNREKLLDPeelpqeEL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404 155 GDHSPGNHEQSYVGKRSNRVVRTLQN--TPSLHSRHWGAPQQREGRQQQHH------EELSATPTPLGLQETIAEFLYIA 226
Cdd:pfam08610 161 KDDPSSSGSESWTLPRTGRVLPSLPSsgSPSLQTRTWKPPPSSAEEISSYLlskvltADDIKPPTSLLGRLKGAEVLYIL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404 227 RPLLHLLSLGLWGQRSWKPWLLAGVVDVTSLSLLSDRKGLTRRERRELRRR-----TILLLYYLLRSPFYDRFSEARILF 301
Cdd:pfam08610 241 RPLIYLLALRRFGRRSWKPWLISLALELASRQLRSRGRGGTPRHLSALEREelkrrGLLLLLYLLRGPFYDNYTRPKIES 320
                         330       340
                  ....*....|....*....|....*...
gi 1812229404 302 lLQLLADHVPGVGLVTRPLMDYLPTWQK 329
Cdd:pfam08610 321 -LALLLEGVPLLGLVGGPLEDYLPLWQE 347
 
Name Accession Description Interval E-value
Pex16 pfam08610
Peroxisomal membrane protein (Pex16); Pex16 is a peripheral protein located at the matrix face ...
10-329 7.93e-108

Peroxisomal membrane protein (Pex16); Pex16 is a peripheral protein located at the matrix face of the peroxisomal membrane.


Pssm-ID: 462535  Cd Length: 347  Bit Score: 318.46  E-value: 7.93e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404  10 RYQEYVTRHPAATAQLETAVRGFSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKL---------PVSLSQQ 80
Cdd:pfam08610   2 AYEKFVRKNPSAVSQIESTLRSLTYLLPGRFRDSEIASELLYSLLNLLSLYNDSILSRAVKSPPhtrytrfwtKKSPLYR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404  81 KLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALVQLAKAVLRMLLLLWFKAGLQTSPPIvPLDRETQAQP------PD 154
Cdd:pfam08610  82 RLARLLTVLEYTELLLEMAARRLWGEKGRWRVIVLIEAIKAVLRLLLLRLTKSRPLLSPPI-PPNREKLLDPeelpqeEL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404 155 GDHSPGNHEQSYVGKRSNRVVRTLQN--TPSLHSRHWGAPQQREGRQQQHH------EELSATPTPLGLQETIAEFLYIA 226
Cdd:pfam08610 161 KDDPSSSGSESWTLPRTGRVLPSLPSsgSPSLQTRTWKPPPSSAEEISSYLlskvltADDIKPPTSLLGRLKGAEVLYIL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812229404 227 RPLLHLLSLGLWGQRSWKPWLLAGVVDVTSLSLLSDRKGLTRRERRELRRR-----TILLLYYLLRSPFYDRFSEARILF 301
Cdd:pfam08610 241 RPLIYLLALRRFGRRSWKPWLISLALELASRQLRSRGRGGTPRHLSALEREelkrrGLLLLLYLLRGPFYDNYTRPKIES 320
                         330       340
                  ....*....|....*....|....*...
gi 1812229404 302 lLQLLADHVPGVGLVTRPLMDYLPTWQK 329
Cdd:pfam08610 321 -LALLLEGVPLLGLVGGPLEDYLPLWQE 347
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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