![](files/infoQ.gif)
DNA repair protein RAD51 homolog 3 isoform 2 [Homo sapiens]
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | |||
recomb_radA super family | cl31184 | DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
21-134 | 1.24e-14 | |||
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair] The actual alignment was detected with superfamily member TIGR02236: Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 68.62 E-value: 1.24e-14
|
|||||||
Name | Accession | Description | Interval | E-value | |||
recomb_radA | TIGR02236 | DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
21-134 | 1.24e-14 | |||
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 68.62 E-value: 1.24e-14
|
|||||||
radA | PRK04301 | DNA repair and recombination protein RadA; Validated |
10-134 | 5.13e-14 | |||
DNA repair and recombination protein RadA; Validated Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 66.82 E-value: 5.13e-14
|
|||||||
Rad51 | pfam08423 | Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
86-134 | 3.30e-07 | |||
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein. Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 47.30 E-value: 3.30e-07
|
|||||||
XRCC3 | cd19491 | XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
107-134 | 1.20e-06 | |||
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site. Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 45.75 E-value: 1.20e-06
|
|||||||
RAD55 | COG0467 | RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
107-134 | 3.03e-03 | |||
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 36.05 E-value: 3.03e-03
|
|||||||
Name | Accession | Description | Interval | E-value | |||
recomb_radA | TIGR02236 | DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
21-134 | 1.24e-14 | |||
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 68.62 E-value: 1.24e-14
|
|||||||
radA | PRK04301 | DNA repair and recombination protein RadA; Validated |
10-134 | 5.13e-14 | |||
DNA repair and recombination protein RadA; Validated Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 66.82 E-value: 5.13e-14
|
|||||||
PTZ00035 | PTZ00035 | Rad51 protein; Provisional |
26-134 | 1.06e-07 | |||
Rad51 protein; Provisional Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 49.23 E-value: 1.06e-07
|
|||||||
Rad51 | pfam08423 | Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
86-134 | 3.30e-07 | |||
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein. Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 47.30 E-value: 3.30e-07
|
|||||||
PLN03186 | PLN03186 | DNA repair protein RAD51 homolog; Provisional |
26-134 | 6.07e-07 | |||
DNA repair protein RAD51 homolog; Provisional Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 47.03 E-value: 6.07e-07
|
|||||||
XRCC3 | cd19491 | XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
107-134 | 1.20e-06 | |||
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site. Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 45.75 E-value: 1.20e-06
|
|||||||
PLN03187 | PLN03187 | meiotic recombination protein DMC1 homolog; Provisional |
8-134 | 3.09e-06 | |||
meiotic recombination protein DMC1 homolog; Provisional Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 44.77 E-value: 3.09e-06
|
|||||||
Rad51B | cd19493 | RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
108-134 | 3.27e-06 | |||
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 44.62 E-value: 3.27e-06
|
|||||||
recomb_DMC1 | TIGR02238 | meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
26-134 | 5.45e-06 | |||
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis. Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 44.00 E-value: 5.45e-06
|
|||||||
radB | PRK09361 | DNA repair and recombination protein RadB; Provisional |
100-134 | 1.56e-05 | |||
DNA repair and recombination protein RadB; Provisional Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 42.54 E-value: 1.56e-05
|
|||||||
Rad51C | cd19492 | RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
118-134 | 1.72e-05 | |||
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling. Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 42.21 E-value: 1.72e-05
|
|||||||
PRK09302 | PRK09302 | circadian clock protein KaiC; Reviewed |
107-132 | 3.38e-05 | |||
circadian clock protein KaiC; Reviewed Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 41.79 E-value: 3.38e-05
|
|||||||
DMC1 | cd19514 | homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
100-134 | 9.58e-05 | |||
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings. Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 40.42 E-value: 9.58e-05
|
|||||||
archRadB | cd01394 | archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
100-134 | 1.45e-04 | |||
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear. Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 39.60 E-value: 1.45e-04
|
|||||||
KaiC-N | cd19485 | N-terminal domain of Circadian Clock Protein Kaic; KaiC is a circadian clock protein, most ... |
107-132 | 1.75e-04 | |||
N-terminal domain of Circadian Clock Protein Kaic; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation. Pssm-ID: 410893 [Multi-domain] Cd Length: 226 Bit Score: 39.66 E-value: 1.75e-04
|
|||||||
recomb_RAD51 | TIGR02239 | DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
26-134 | 3.11e-04 | |||
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012). Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 38.94 E-value: 3.11e-04
|
|||||||
archRadA | cd19515 | archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
100-134 | 6.00e-04 | |||
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR) Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 38.11 E-value: 6.00e-04
|
|||||||
ATPase | pfam06745 | KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
107-132 | 1.02e-03 | |||
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria. Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 37.23 E-value: 1.02e-03
|
|||||||
RAD55 | COG0467 | RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
107-134 | 3.03e-03 | |||
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 36.05 E-value: 3.03e-03
|
|||||||
KaiC-like | cd01124 | Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
107-132 | 3.75e-03 | |||
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation. Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 35.70 E-value: 3.75e-03
|
|||||||
Rad51_DMC1_archRadA | cd01123 | recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
100-134 | 6.52e-03 | |||
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 . Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 35.20 E-value: 6.52e-03
|
|||||||
Rad51D | cd19489 | RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
112-134 | 6.91e-03 | |||
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 34.92 E-value: 6.91e-03
|
|||||||
Blast search parameters | ||||
|