NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1879298448|ref|NP_001372614|]
View 

microtubule-associated protein 4 isoform 69 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 920-949 1.33e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.33e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298448  920 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 949
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 951-980 2.08e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 2.08e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298448  951 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 980
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 982-1012 4.28e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.80  E-value: 4.28e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298448  982 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 1012
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 859-880 2.23e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.49  E-value: 2.23e-08
                           10        20
                   ....*....|....*....|..
gi 1879298448  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
679-917 1.25e-03

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  679 SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 758
Cdd:PRK07003   366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  759 PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---- 834
Cdd:PRK07003   446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDApaaa 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  835 ---KPTSAKPSSTTPRLSRLATNTSAP--DLKNVRSKVGSTeniKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPI 909
Cdd:PRK07003   526 appAPEARPPTPAAAAPAARAGGAAAAldVLRNAGMRVSSD---RGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRAR 602


                   ....*...
gi 1879298448  910 ASAQKQPA 917
Cdd:PRK07003   603 AATGDAPP 610
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 920-949 1.33e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.33e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298448  920 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 949
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 951-980 2.08e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 2.08e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298448  951 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 980
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 982-1012 4.28e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.80  E-value: 4.28e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298448  982 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 1012
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 859-880 2.23e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.49  E-value: 2.23e-08
                           10        20
                   ....*....|....*....|..
gi 1879298448  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
679-917 1.25e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  679 SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 758
Cdd:PRK07003   366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  759 PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---- 834
Cdd:PRK07003   446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDApaaa 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  835 ---KPTSAKPSSTTPRLSRLATNTSAP--DLKNVRSKVGSTeniKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPI 909
Cdd:PRK07003   526 appAPEARPPTPAAAAPAARAGGAAAAldVLRNAGMRVSSD---RGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRAR 602


                   ....*...
gi 1879298448  910 ASAQKQPA 917
Cdd:PRK07003   603 AATGDAPP 610
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 920-949 1.33e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.33e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298448  920 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 949
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 951-980 2.08e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 2.08e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298448  951 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 980
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 982-1012 4.28e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.80  E-value: 4.28e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298448  982 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 1012
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 859-880 2.23e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.49  E-value: 2.23e-08
                           10        20
                   ....*....|....*....|..
gi 1879298448  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
679-917 1.25e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  679 SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 758
Cdd:PRK07003   366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  759 PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---- 834
Cdd:PRK07003   446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDApaaa 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  835 ---KPTSAKPSSTTPRLSRLATNTSAP--DLKNVRSKVGSTeniKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPI 909
Cdd:PRK07003   526 appAPEARPPTPAAAAPAARAGGAAAAldVLRNAGMRVSSD---RGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRAR 602


                   ....*...
gi 1879298448  910 ASAQKQPA 917
Cdd:PRK07003   603 AATGDAPP 610
PRK13914 PRK13914
invasion associated endopeptidase;
656-872 2.70e-03

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 41.71  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  656 SQPSELSSETSGIARPEEGRPVV-SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 734
Cdd:PRK13914   145 STPVAPTQEVKKETTTQQAAPAAeTKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWALSVKYGVSVQDI 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  735 VAKTTTAAAVASTGPS---SRSPSTLLPKkpTAIKTEGKPAEvkKMTAKSVPADLSrpKSTSTSSMKKTTTLSGTAPAAG 811
Cdd:PRK13914   225 MSWNNLSSSSIYVGQKlaiKQTANTATPK--AEVKTEAPAAE--KQAAPVVKENTN--TNTATTEKKETTTQQQTAPKAP 298

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1879298448  812 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP-RLSRLATNTSAPDLKNVRSKVGSTEN 872
Cdd:PRK13914   299 TEAAKPAPAPSTNTNANKTNTNTNTNTNNTNTSTPsKNTNTNTNSNTNTNSNTNANQGSSNN 360
PHA03247 PHA03247
large tegument protein UL36; Provisional
 575-852 4.83e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 4.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  575 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 653
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  654 CNSQPSELSSETSGiARPEEGRPVVsGTGNDITTPPNKELPPSPEKK----TKPIADAKAPEKRASPSKP--------AS 721
Cdd:PHA03247  2669 RLGRAAQASSPPQR-PRRRAARPTV-GSLTSLADPPPPPPTPEPAPHalvsATPLPPGPAAARQASPALPaapappavPA 2746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  722 APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTT 801
Cdd:PHA03247  2747 GPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1879298448  802 TLsgtAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKP----SSTTPRLSRLA 852
Cdd:PHA03247  2827 PL---PPPTSAQPTAPPPPPGPPPPSLPlggsvapggDVRRRPPSRSPAakpaAPARPPVRRLA 2887
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 692-841 5.11e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 5.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  692 ELPPSPEKKTKPI---ADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSPStlLPKKPT 763
Cdd:PTZ00449   509 EPPEGPEASGLPPkapGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPE--FPKDPK 586

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  764 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--PFIDKKPTSA 839
Cdd:PTZ00449   587 HPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiIKSPKPPKSP 663


                   ..
gi 1879298448  840 KP 841
Cdd:PTZ00449   664 KP 665
PHA03247 PHA03247
large tegument protein UL36; Provisional
 549-854 7.74e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 7.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  549 VPALKTEAPLAKDGVLTLANNVTPAKdvPPLSETEATPVPIKDMEIAQTQKGisedshleslqdvgqSAAPTfmisPETV 628
Cdd:PHA03247  2716 VSATPLPPGPAAARQASPALPAAPAP--PAVPAGPATPGGPARPARPPTTAG---------------PPAPA----PPAA 2774

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  629 TGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSG--IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPIAD 706
Cdd:PHA03247  2775 PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLApaAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG 2854

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  707 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 786
Cdd:PHA03247  2855 SVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP 2934

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298448  787 SRPKSTS----TSSMKKTTTLSGTAPA---AGVVPSRVKAT------PMPSRPSTTPfidkkPTSAKPSSTTPRLSRLAT 853
Cdd:PHA03247  2935 PPPRPQPplapTTDPAGAGEPSGAVPQpwlGALVPGRVAVPrfrvpqPAPSREAPAS-----STPPLTGHSLSRVSSWAS 3009


                   .
gi 1879298448  854 N 854
Cdd:PHA03247  3010 S 3010
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH