NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1862755554|ref|NP_001371785|]
View 

microtubule-associated protein 4 isoform 124 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 743-772 1.91e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 1.91e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862755554 743 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 772
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 364-708 8.42e-11

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.12  E-value: 8.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  364 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 442
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  443 CNSQPSELSSETSGiARPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTI 522
Cdd:PHA03247  2669 RLGRAAQASSPPQR-PRRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV 2744

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  523 GGLNKKPMSLASGLVPAAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 600
Cdd:PHA03247  2745 PAGPATPGGPARPARPPTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  601 TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVV 674
Cdd:PHA03247  2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQ 2904

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1862755554  675 PSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 708
Cdd:PHA03247  2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 774-804 3.78e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.41  E-value: 3.78e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862755554 774 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 804
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 720-741 2.01e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.49  E-value: 2.01e-08
                          10        20
                  ....*....|....*....|..
gi 1862755554 720 DLKNVRSKVGSTENIKHQPGGG 741
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 743-772 1.91e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 1.91e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862755554 743 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 772
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 364-708 8.42e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.12  E-value: 8.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  364 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 442
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  443 CNSQPSELSSETSGiARPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTI 522
Cdd:PHA03247  2669 RLGRAAQASSPPQR-PRRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV 2744

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  523 GGLNKKPMSLASGLVPAAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 600
Cdd:PHA03247  2745 PAGPATPGGPARPARPPTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  601 TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVV 674
Cdd:PHA03247  2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQ 2904

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1862755554  675 PSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 708
Cdd:PHA03247  2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 774-804 3.78e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.41  E-value: 3.78e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862755554 774 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 804
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 720-741 2.01e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.49  E-value: 2.01e-08
                          10        20
                  ....*....|....*....|..
gi 1862755554 720 DLKNVRSKVGSTENIKHQPGGG 741
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 357-719 1.36e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 357 NNVTPAKDVPPLSETEAT-PVPikdmeiAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLE 435
Cdd:pfam05109 457 NLTAPASTGPTVSTADVTsPTP------AGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTP 530

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 436 KLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPspekkTKPLATTQPAKTSTSKAKTQPTSlpk 515
Cdd:pfam05109 531 TPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSP-----TSAVTTPTPNATSPTVGETSPQA--- 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 516 QPAPTTIGGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSKPASAPASR 587
Cdd:pfam05109 603 NTTNHTLGGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHMPLLTSAHP 675

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 588 SGSKSTQTVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRPKSTSTSSM 658
Cdd:pfam05109 676 TGGENITQVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTAVPTVTSTG 755

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862755554 659 KKTTTLSGTAPAAGV-VPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 719
Cdd:pfam05109 756 GKANSTTGGKHTTGHgARTSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 743-772 1.91e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 1.91e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862755554 743 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 772
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 364-708 8.42e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.12  E-value: 8.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  364 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 442
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  443 CNSQPSELSSETSGiARPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTI 522
Cdd:PHA03247  2669 RLGRAAQASSPPQR-PRRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV 2744

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  523 GGLNKKPMSLASGLVPAAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 600
Cdd:PHA03247  2745 PAGPATPGGPARPARPPTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  601 TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVV 674
Cdd:PHA03247  2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQ 2904

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1862755554  675 PSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 708
Cdd:PHA03247  2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
PHA03247 PHA03247
large tegument protein UL36; Provisional
 442-719 9.01e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.12  E-value: 9.01e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  442 PCNSQPSELSSETSGIARPEEGRPVVSG--TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAP 519
Cdd:PHA03247  2575 PRPSEPAVTSRARRPDAPPQSARPRAPVddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRD 2654

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  520 TTIGG---LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDvkpkpIADAKAPEKRASPSKPASAPASRSGSKSTQTV 596
Cdd:PHA03247  2655 DPAPGrvsRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTS-----LADPPPPPPTPEPAPHALVSATPLPPGPAAAR 2729

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  597 AKTTTAAAVASTGPSSRSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTstssmkktttlsgtAPAAGVVPS 676
Cdd:PHA03247  2730 QASPALPAAPAPPAVPAGPAT--PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT--------------RPAVASLSE 2793

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1862755554  677 RVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 719
Cdd:PHA03247  2794 SRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 774-804 3.78e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.41  E-value: 3.78e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862755554 774 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 804
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 720-741 2.01e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.49  E-value: 2.01e-08
                          10        20
                  ....*....|....*....|..
gi 1862755554 720 DLKNVRSKVGSTENIKHQPGGG 741
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 457-714 1.95e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.33  E-value: 1.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  457 IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTS----LPKQPAPTTIGGLNKKPmSL 532
Cdd:PHA03247  2740 APPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESReslpSPWDPADPPAAVLAPAA-AL 2818

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  533 ASGLVPAAP-PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 611
Cdd:PHA03247  2819 PPAASPAGPlPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  612 SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADlsRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTP 691
Cdd:PHA03247  2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPR 2976

                          250       260
                   ....*....|....*....|....*
gi 1862755554  692 FI--DKKPTSAKPSSTTPRLSRLAT 714
Cdd:PHA03247  2977 FRvpQPAPSREAPASSTPPLTGHSL 3001
PHA03247 PHA03247
large tegument protein UL36; Provisional
 483-708 4.08e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 4.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  483 PPSPEKKTKPlattqPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAvASARPSILPSKDVKP 562
Cdd:PHA03247  2551 PPPPLPPAAP-----PAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPR-GPAPPSPLPPDTHAP 2624

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  563 KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIktegkPAEVKKMTAKS 642
Cdd:PHA03247  2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA-----RPTVGSLTSLA 2699

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1862755554  643 VPADLSR---PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP-----TSAKPSSTTPR 708
Cdd:PHA03247  2700 DPPPPPPtpePAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARParpptTAGPPAPAPPA 2773
PHA03247 PHA03247
large tegument protein UL36; Provisional
 449-726 4.26e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 4.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  449 ELSSETSGIARPEEGrPVVSGTGNDITTPPNKELPPSPE-----KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPttig 523
Cdd:PHA03247  2542 ELASDDAGDPPPPLP-PAAPPAAPDRSVPPPRPAPRPSEpavtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSP---- 2616

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  524 glnkkpmslasgLVPAAPPKRPAVASARPSilPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAA 603
Cdd:PHA03247  2617 ------------LPPDTHAPDPPPPSPSPA--ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQR 2682

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  604 AVASTGPSSRSPSTLLPKKPTAIKTegkPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVkaTPM 683
Cdd:PHA03247  2683 PRRRAARPTVGSLTSLADPPPPPPT---PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP--ARP 2757

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1862755554  684 PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 726
Cdd:PHA03247  2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 440-719 6.81e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 6.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  440 RKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITT------PPNKELPPSPEKKTKPLATTQPAKT------------ 501
Cdd:PHA03307    59 AAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLapaspaREGSPTPPGPSSPDPPPPTPPPASPppspapdlseml 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  502 -----STSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA-----PPKRPAVASARPSILPSKDVKPKPIADAKAP 571
Cdd:PHA03307   139 rpvgsPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETarapsSPPAEPPPSTPPAAASPRPPRRSSPISASAS 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  572 EKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIktEGKPAEVKKMTAKSVPADLSR-- 649
Cdd:PHA03307   219 SPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEAS--GWNGPSSRPGPASSSSSPRERsp 296

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1862755554  650 ---------PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 719
Cdd:PHA03307   297 spspsspgsGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAP 375
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
516-707 1.39e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 45.61  E-value: 1.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 516 QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASAR-------PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRS 588
Cdd:PRK07003  359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASavpavtaVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 589 GSKSTQtvaktttaaavastgpssrSPSTLLPKKPTAIKTEGKPAEvkkmtAKSVPADLSRPKSTSTSSMKKTTTLSGTA 668
Cdd:PRK07003  439 GDDAAD-------------------GDAPVPAKANARASADSRCDE-----RDAQPPADSGSASAPASDAPPDAAFEPAP 494

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1862755554 669 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 707
Cdd:PRK07003  495 RAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533
PHA03247 PHA03247
large tegument protein UL36; Provisional
 197-590 3.80e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 3.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  197 SPHSESFVSPEAVAEPPQPTAEISSAEKVALSSETEVALARdmtlPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIA 276
Cdd:PHA03247  2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR----AAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT 2707

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  277 PAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLP-----PEMEVALTEDQVPALKTEAPLAKDG 351
Cdd:PHA03247  2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARParpptTAGPPAPAPPAAPAAGPPRRLTRPA 2787

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  352 VLTLANNvTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTgkkcSLPAEEd 431
Cdd:PHA03247  2788 VASLSES-RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGS----VAPGGD- 2861

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  432 svlekLGERKPCNSQPSELSSETSGIARpEEGRPVVSGTGNDITTPPNK-ELPPSPEKKTKPLATTQPAKTSTSKAKTQP 510
Cdd:PHA03247  2862 -----VRRRPPSRSPAAKPAAPARPPVR-RLARPAVSRSTESFALPPDQpERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  511 TSLPKQPAPTTIGglnKKPMSLASGLVPAapPKRPAVASARPSILPSKDVKPKPIADAKAPekraSPSKPASAPASRSGS 590
Cdd:PHA03247  2936 PPRPQPPLAPTTD---PAGAGEPSGAVPQ--PWLGALVPGRVAVPRFRVPQPAPSREAPAS----STPPLTGHSLSRVSS 3006
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 447-711 4.78e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 4.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  447 PSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK--------PLATTQPAKTSTSKAKTQPTSLPKQPA 518
Cdd:PHA03307   122 PPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAassrqaalPLSSPEETARAPSSPPAEPPPSTPPAA 201

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  519 PTTIGGLNKKPMSLASGLVPAAPPKRPAV--ASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 596
Cdd:PHA03307   202 ASPRPPRRSSPISASASSPAPAPGRSAADdaGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSR 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  597 AKTTTAaavaSTGPSSRSPSTLlPKKPTAIKTEGKPAEVKKMTAKSvPADLSRPKSTSTSSMKKTTTlSGTAPAAGVVPS 676
Cdd:PHA03307   282 PGPASS----SSSPRERSPSPS-PSSPGSGPAPSSPRASSSSSSSR-ESSSSSTSSSSESSRGAAVS-PGPSPSRSPSPS 354

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1862755554  677 RVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSR 711
Cdd:PHA03307   355 RPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRR 389
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 582-856 6.90e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 6.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 582 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 661
Cdd:pfam05109 459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 662 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTENIKHQP 738
Cdd:pfam05109 530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSPQANTT 605

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 739 GGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLC 818
Cdd:pfam05109 606 NHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVT 685

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1862755554 819 PGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 856
Cdd:pfam05109 686 PASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
454-719 9.62e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 9.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 454 TSGIARPEEGRPVVSGT--GNDITTPPNKELPPSPEKKTKPLATTQPA--KTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 529
Cdd:PRK07003  363 TGGGAPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALapKAAAAAAATRAEAPPAAPAPPATADRGDDA 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 530 MSlasglVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 609
Cdd:PRK07003  443 AD-----GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 610 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 689
Cdd:PRK07003  518 REDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVP 597

                         250       260       270
                  ....*....|....*....|....*....|
gi 1862755554 690 TPFIDKKPTSAKPSSTTPRLSRLATNTSAP 719
Cdd:PRK07003  598 TPRARAATGDAPPNGAARAEQAAESRGAPP 627
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 357-719 1.36e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 357 NNVTPAKDVPPLSETEAT-PVPikdmeiAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLE 435
Cdd:pfam05109 457 NLTAPASTGPTVSTADVTsPTP------AGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTP 530

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 436 KLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPspekkTKPLATTQPAKTSTSKAKTQPTSlpk 515
Cdd:pfam05109 531 TPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSP-----TSAVTTPTPNATSPTVGETSPQA--- 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 516 QPAPTTIGGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSKPASAPASR 587
Cdd:pfam05109 603 NTTNHTLGGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHMPLLTSAHP 675

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 588 SGSKSTQTVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRPKSTSTSSM 658
Cdd:pfam05109 676 TGGENITQVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTAVPTVTSTG 755

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862755554 659 KKTTTLSGTAPAAGV-VPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 719
Cdd:pfam05109 756 GKANSTTGGKHTTGHgARTSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 454-719 1.95e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.83  E-value: 1.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 454 TSGIARPEegrpVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 531
Cdd:pfam05109 436 TTGFAAPN----TTTGLPSSTHVPTNLTAPAStgPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTS 511

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 532 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 611
Cdd:pfam05109 512 AVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNAT 591

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 612 SRSPSTLLPKKPTAIKTEGKPAEVKKMTA--KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV--KATPMPSRP 687
Cdd:pfam05109 592 SPTVGETSPQANTTNHTLGGTSSTPVVTSppKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSdnSTSHMPLLT 671

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1862755554 688 STTPFIDKKPTSAKPSSTTPRlsRLATNTSAP 719
Cdd:pfam05109 672 SAHPTGGENITQVTPASTSTH--HVSTSSPAP 701
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 541-702 2.23e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.60  E-value: 2.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 541 PPKRPAvASARPsilpskdvkPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSP 615
Cdd:PTZ00449  510 PPEGPE-ASGLP---------PKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKP 579

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 616 StlLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--P 691
Cdd:PTZ00449  580 E--FPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiI 654

                         170
                  ....*....|.
gi 1862755554 692 FIDKKPTSAKP 702
Cdd:PTZ00449  655 KSPKPPKSPKP 665
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 442-717 3.47e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.21  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 442 PCNSQPSELSSETS-GIARPEEGRPVVSGTGNDITTPPNkelPPSPEKKTK-PLATTQPAKTSTSKAKTQPTS--LPKQP 517
Cdd:PTZ00449  524 PGDKEGEEGEHEDSkESDEPKEGGKPGETKEGEVGKKPG---PAKEHKPSKiPTLSKKPEFPKDPKHPKDPEEpkKPKRP 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 518 APTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPA---------------S 582
Cdd:PTZ00449  601 RSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKppfdpkfkekfyddyL 680

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 583 APASRSGSKSTQTVAKTTTAAAVASTGPSS-----RSPSTLLPKKPTAIKTEGKPaeVKKMTAKSV-PADLSRPKSTSTS 656
Cdd:PTZ00449  681 DAAAKSKETKTTVVLDESFESILKETLPETpgtpfTTPRPLPPKLPRDEEFPFEP--IGDPDAEQPdDIEFFTPPEEERT 758

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1862755554 657 SMKKTttlSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP------------RLSRLATNTS 717
Cdd:PTZ00449  759 FFHET---PADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDSPSEHEDKPpgdhpslpkkrhRLDGLALSTT 828
PRK13808 PRK13808
adenylate kinase; Provisional
 490-631 6.84e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 39.49  E-value: 6.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554 490 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTtigglnKKPMSLASGLVPAAPPKRPAVASARPsilPSKDVKPKPIADAK 569
Cdd:PRK13808  199 AKKAAKTPAAKSGAKKASAKAKSAAKKVSKK------KAAKTAVSAKKAAKTAAKAAKKAKKT---AKKALKKAAKAVKK 269

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862755554 570 APEKraspSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 631
Cdd:PRK13808  270 AAKK----AAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKK 327
PHA03247 PHA03247
large tegument protein UL36; Provisional
 476-684 9.40e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 9.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  476 TPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPtSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPS 553
Cdd:PHA03247  2812 LAPAAALPPAasPAGPLPPPTSAQPTAPPPPPGPPPP-SLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPA 2890

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862755554  554 ILPSKDV------------KPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPk 621
Cdd:PHA03247  2891 VSRSTESfalppdqperppQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP- 2969

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1862755554  622 kptaikteGKPAEVKKMTAKSVPadlSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMP 684
Cdd:PHA03247  2970 --------GRVAVPRFRVPQPAP---SREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPP 3021
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH