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transcriptional repressor p66-alpha isoform 3 [Homo sapiens]
P66_CC and GATA domain-containing protein( domain architecture ID 10964881)
protein containing domains Med21, P66_CC, and GATA
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
P66_CC | pfam16563 | Coiled-coil and interaction region of P66A and P66B with MBD2; This family is a short ... |
137-176 | 2.30e-16 | |||
Coiled-coil and interaction region of P66A and P66B with MBD2; This family is a short coiled-coil interaction region on the transcriptional repressors P66A and P66B. The P66A and B, or alpha and beta, complex with MBDs or methyl-binding domain-containing proteins via a coiled-coil region on each. This P66-MBD2 complex forms part of an assembly with NuRD, nucleosome remodelling and deacetylation protein. MBD2-NuRD binds methylated DNA and regulates transcription of eg, the foetal beta-globin gene during development. : Pssm-ID: 465178 Cd Length: 40 Bit Score: 72.84 E-value: 2.30e-16
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GATA | pfam00320 | GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ... |
418-452 | 4.76e-08 | |||
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain. : Pssm-ID: 425605 [Multi-domain] Cd Length: 36 Bit Score: 49.24 E-value: 4.76e-08
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Med21 super family | cl12769 | Subunit 21 of Mediator complex; Med21 has been known as Srb7 in yeasts, hSrb7 in humans and ... |
98-167 | 3.23e-03 | |||
Subunit 21 of Mediator complex; Med21 has been known as Srb7 in yeasts, hSrb7 in humans and Trap 19 in Drosophila. The heterodimer of the two subunits Med7 and Med21 appears to act as a hinge between the middle and the tail regions of Mediator. The actual alignment was detected with superfamily member pfam11221: Pssm-ID: 463241 Cd Length: 134 Bit Score: 37.96 E-value: 3.23e-03
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Name | Accession | Description | Interval | E-value | |||
P66_CC | pfam16563 | Coiled-coil and interaction region of P66A and P66B with MBD2; This family is a short ... |
137-176 | 2.30e-16 | |||
Coiled-coil and interaction region of P66A and P66B with MBD2; This family is a short coiled-coil interaction region on the transcriptional repressors P66A and P66B. The P66A and B, or alpha and beta, complex with MBDs or methyl-binding domain-containing proteins via a coiled-coil region on each. This P66-MBD2 complex forms part of an assembly with NuRD, nucleosome remodelling and deacetylation protein. MBD2-NuRD binds methylated DNA and regulates transcription of eg, the foetal beta-globin gene during development. Pssm-ID: 465178 Cd Length: 40 Bit Score: 72.84 E-value: 2.30e-16
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GATA | pfam00320 | GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ... |
418-452 | 4.76e-08 | |||
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain. Pssm-ID: 425605 [Multi-domain] Cd Length: 36 Bit Score: 49.24 E-value: 4.76e-08
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Med21 | pfam11221 | Subunit 21 of Mediator complex; Med21 has been known as Srb7 in yeasts, hSrb7 in humans and ... |
98-167 | 3.23e-03 | |||
Subunit 21 of Mediator complex; Med21 has been known as Srb7 in yeasts, hSrb7 in humans and Trap 19 in Drosophila. The heterodimer of the two subunits Med7 and Med21 appears to act as a hinge between the middle and the tail regions of Mediator. Pssm-ID: 463241 Cd Length: 134 Bit Score: 37.96 E-value: 3.23e-03
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Name | Accession | Description | Interval | E-value | |||
P66_CC | pfam16563 | Coiled-coil and interaction region of P66A and P66B with MBD2; This family is a short ... |
137-176 | 2.30e-16 | |||
Coiled-coil and interaction region of P66A and P66B with MBD2; This family is a short coiled-coil interaction region on the transcriptional repressors P66A and P66B. The P66A and B, or alpha and beta, complex with MBDs or methyl-binding domain-containing proteins via a coiled-coil region on each. This P66-MBD2 complex forms part of an assembly with NuRD, nucleosome remodelling and deacetylation protein. MBD2-NuRD binds methylated DNA and regulates transcription of eg, the foetal beta-globin gene during development. Pssm-ID: 465178 Cd Length: 40 Bit Score: 72.84 E-value: 2.30e-16
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GATA | pfam00320 | GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ... |
418-452 | 4.76e-08 | |||
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain. Pssm-ID: 425605 [Multi-domain] Cd Length: 36 Bit Score: 49.24 E-value: 4.76e-08
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Med21 | pfam11221 | Subunit 21 of Mediator complex; Med21 has been known as Srb7 in yeasts, hSrb7 in humans and ... |
98-167 | 3.23e-03 | |||
Subunit 21 of Mediator complex; Med21 has been known as Srb7 in yeasts, hSrb7 in humans and Trap 19 in Drosophila. The heterodimer of the two subunits Med7 and Med21 appears to act as a hinge between the middle and the tail regions of Mediator. Pssm-ID: 463241 Cd Length: 134 Bit Score: 37.96 E-value: 3.23e-03
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Blast search parameters | ||||
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