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Conserved domains on  [gi|1845981688|ref|NP_001369783|]
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N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 [Mus musculus]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229488)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Galactosyl_T super family cl21608
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 106-295 3.90e-43

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


The actual alignment was detected with superfamily member pfam01762:

Pssm-ID: 473923 [Multi-domain]  Cd Length: 195  Bit Score: 147.86  E-value: 3.90e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 106 EQRSAIRSTWGRAGSWARGRqLKLVFLLGVAGPVPP--AQLLVYESWQFDDILQWDFAEDFFNLTLKELHVQRWIAAACT 183
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGR-IKSLFLVGLSADTDGkvADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 184 QAHFILKGDDDVFIHVPNVLEFLEG--WDPAQDFLVGDVIRLARPNRNTKVKYFIPFSMYRARHYPPYAGGGGYVMSQAT 261
Cdd:pfam01762  80 SAKYIGKIDDDVYFFPDKLLSLLDNgnIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDA 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1845981688 262 VRHLHMAMEEAELFPIDDVFVGMCLRKLGVTPIH 295
Cdd:pfam01762 160 AEKLLKASKHRRFLQIEDVYVGILANDLGISRVN 193
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 106-295 3.90e-43

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 147.86  E-value: 3.90e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 106 EQRSAIRSTWGRAGSWARGRqLKLVFLLGVAGPVPP--AQLLVYESWQFDDILQWDFAEDFFNLTLKELHVQRWIAAACT 183
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGR-IKSLFLVGLSADTDGkvADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 184 QAHFILKGDDDVFIHVPNVLEFLEG--WDPAQDFLVGDVIRLARPNRNTKVKYFIPFSMYRARHYPPYAGGGGYVMSQAT 261
Cdd:pfam01762  80 SAKYIGKIDDDVYFFPDKLLSLLDNgnIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDA 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1845981688 262 VRHLHMAMEEAELFPIDDVFVGMCLRKLGVTPIH 295
Cdd:pfam01762 160 AEKLLKASKHRRFLQIEDVYVGILANDLGISRVN 193
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 106-334 6.14e-13

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 69.83  E-value: 6.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 106 EQRSAIRSTWGRAGSwARGRQLKLVFLLGV-AGPVPPAQLLVyESWQFDDILQWDFAeDFFNL-TLKELhvqrwiaAACT 183
Cdd:PLN03133  399 KRRMAVRRTWMQYDA-VRSGAVAVRFFVGLhKNQMVNEELWN-EARTYGDIQLMPFV-DYYSLiTWKTL-------AICI 468

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 184 ------QAHFILKGDDDVFIHVPNVLEFLEGWDPAQDFLVGDVIRLARPNRNTKVKYFIPFSMYRARHYPPYAGGGGYVM 257
Cdd:PLN03133  469 fgtevvSAKYVMKTDDDAFVRVDEVLASLKRTNVSHGLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVV 548

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 258 SQATVRHLHMAMEEAEL--FPIDDVFVGMC---LRKLGVT-------PIHHAGFKTfgiqqplnprdpclykGLLLVHRL 325
Cdd:PLN03133  549 SRDIAKEVYKRHKEGRLkmFKLEDVAMGIWiaeMKKEGLEvkyendgRIYNEGCKD----------------GYVVAHYQ 612


                  ....*....
gi 1845981688 326 SPLEMWTMW 334
Cdd:PLN03133  613 SPREMLCLW 621
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 106-295 3.90e-43

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 147.86  E-value: 3.90e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 106 EQRSAIRSTWGRAGSWARGRqLKLVFLLGVAGPVPP--AQLLVYESWQFDDILQWDFAEDFFNLTLKELHVQRWIAAACT 183
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGR-IKSLFLVGLSADTDGkvADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 184 QAHFILKGDDDVFIHVPNVLEFLEG--WDPAQDFLVGDVIRLARPNRNTKVKYFIPFSMYRARHYPPYAGGGGYVMSQAT 261
Cdd:pfam01762  80 SAKYIGKIDDDVYFFPDKLLSLLDNgnIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRDA 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1845981688 262 VRHLHMAMEEAELFPIDDVFVGMCLRKLGVTPIH 295
Cdd:pfam01762 160 AEKLLKASKHRRFLQIEDVYVGILANDLGISRVN 193
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 106-334 6.14e-13

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 69.83  E-value: 6.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 106 EQRSAIRSTWGRAGSwARGRQLKLVFLLGV-AGPVPPAQLLVyESWQFDDILQWDFAeDFFNL-TLKELhvqrwiaAACT 183
Cdd:PLN03133  399 KRRMAVRRTWMQYDA-VRSGAVAVRFFVGLhKNQMVNEELWN-EARTYGDIQLMPFV-DYYSLiTWKTL-------AICI 468

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 184 ------QAHFILKGDDDVFIHVPNVLEFLEGWDPAQDFLVGDVIRLARPNRNTKVKYFIPFSMYRARHYPPYAGGGGYVM 257
Cdd:PLN03133  469 fgtevvSAKYVMKTDDDAFVRVDEVLASLKRTNVSHGLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVV 548

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845981688 258 SQATVRHLHMAMEEAEL--FPIDDVFVGMC---LRKLGVT-------PIHHAGFKTfgiqqplnprdpclykGLLLVHRL 325
Cdd:PLN03133  549 SRDIAKEVYKRHKEGRLkmFKLEDVAMGIWiaeMKKEGLEvkyendgRIYNEGCKD----------------GYVVAHYQ 612


                  ....*....
gi 1845981688 326 SPLEMWTMW 334
Cdd:PLN03133  613 SPREMLCLW 621
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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