|
Name |
Accession |
Description |
Interval |
E-value |
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
305-603 |
0e+00 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 605.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 305 VILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAG 384
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 385 LTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYD 464
Cdd:cd17760 81 LTVTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 465 PQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRNLQPTLSDVGNQ 544
Cdd:cd17760 161 PNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPSKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1807799521 545 VLLRYYQMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17760 241 ILLRYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
2-605 |
1.81e-159 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 473.90 E-value: 1.81e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 2 NSDQVTLVGQVFESYVseyHKNDILLILkerdedAHYP----VVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRrsa 77
Cdd:COG1241 2 ESDLVDKFEEFLRRYK---YRDEILELA------QEYPekrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALR--- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 78 ltilQSLSQPEAVSMKQnLHARISGLPVCPELvrEHIPkTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIk 157
Cdd:COG1241 70 ----EIDLEPYDVSLGD-AHVRITNLPETVPI--RDIR-SDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYV- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 158 adfEQYYT-FCRPSSCPSlesC----------DSSKFTclsglsssptrcrDYQEIKIQEQVQRLSVGSIPRSMKVILED 226
Cdd:COG1241 141 ---PQTGEkLQEPHECPG---CgrqgpfkllpEKSEFI-------------DAQKIRIQEPPEDLPGGQQPQSIDVILED 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 227 DLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFweyyKSDPFAgRNVI 306
Cdd:COG1241 202 DLVGEVRPGDRVTVTGILRIEQRTSGRGKSTIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKEL----SKDPDI-YEKI 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 307 LASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLT 386
Cdd:COG1241 277 IASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLT 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 387 VTAVKD---SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQ 462
Cdd:COG1241 357 AAAVRDdfgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKyGR 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 463 YDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILEN--KGYPSKSEKLWSMEKMKTYfclI--------- 531
Cdd:COG1241 437 FDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVhrAGELLEQEIEEETEEVKPE---Idpdllrkyi 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 532 ----RNLQPTLSDVGNQVLLRYY-QMQRQSDCRNAART-TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQ 605
Cdd:COG1241 514 ayarRNVFPVLTEEAKDLIEDFYvDMRKKGEDEDSPVPiTARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLK 593
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
9-605 |
3.09e-151 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 452.84 E-value: 3.09e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 9 VGQVFESYVSEYHKNDILLILKERDED--AHYP--VVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRrsaltILQSL 84
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEmiAMRKrsLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALK-----EIVEE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 85 SQPEAVSMKQNLHARISGLPvcpELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYY 164
Cdd:NF040949 76 EDPEYAEEVAKFHVRFRNLP---RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESY 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 165 TFC-RPSSCPSLEScdSSKFTCLSGLSssptRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGI 243
Cdd:NF040949 153 EIVePPTVCPVCGK--PGSFRLLQEKS----KFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGI 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 244 V-MQRWKPFQQDVRCEVEIVLKANYIqvnnEQSSGIIMDEEVQKEFEDFWEYYKSDPFAgRNVILASLCPQVFGMYLVKL 322
Cdd:NF040949 227 LrIKPDSSLKKGSRPIFKNYIEANHI----EVSQKELEEVEITEEDEEKILELAKDPWI-REKIIASIAPSIYGHWEIKE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 323 AVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKD--SGEWNLEA 400
Cdd:NF040949 302 AIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDklTGEYYLEA 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 401 GALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQYDPQESVSVNIALGSPL 479
Cdd:NF040949 382 GALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKfGRYDPNRSVAENIDLPPTI 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 480 LSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIR-NLQPTLSDVGNQVLLRYY-QMQRQSD 557
Cdd:NF040949 462 LSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEKVKPEIDPDLLKKYIAYARkYVRPKLTEEAKKLIEDFYvEMRKSSK 541
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1807799521 558 CRNAART----TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQ 605
Cdd:NF040949 542 SSEDPDSpipiTARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLE 593
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
116-603 |
1.26e-143 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 427.45 E-value: 1.26e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 116 KTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVfviKADFEQYYTFCRPSSCPSlESCDS-SKFTCLSGLSsspt 194
Cdd:smart00350 9 RADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGAT---LGPEIQSGRETEPTVCPP-RECQSpTPFSLNHERS---- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 195 RCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVmqRWKPFQ-----QDVRCEVEIVLKANYIQ 269
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIY--RNVPYGfklntVKGLPVFATYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 270 VNNEQSSGIIMDEEVQK----EFEDFWEYYKSDPFAgrNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGE 345
Cdd:smart00350 159 KLDYKRSFEDSSFSVQSlsdeEEEEIRKLSKDPDIY--ERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 346 SHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHD 423
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDpeTREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 424 RTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIIS 502
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPiGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 503 SFILENKGY-----PSKSEKLWSMEKMKTYFCLIR-NLQPTLSDVGNQVLLRYY----QMQRQSDCRNAARTTIRLLESL 572
Cdd:smart00350 397 KHVVDLHRYshpeeDEAFEPPLSQEKLRKYIAYAReKIKPKLSEEAADKLVKAYvdlrKEDSQTESRSSIPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|.
gi 1807799521 573 IRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
304-508 |
7.33e-102 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 309.46 E-value: 7.33e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 304 NVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSA 383
Cdd:pfam00493 16 DKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAPRAVYTSGKGSSAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 384 GLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 460
Cdd:pfam00493 96 GLTAAVVRDpvTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLNARCSILAAANPIf 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1807799521 461 GQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILEN 508
Cdd:pfam00493 176 GRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDL 223
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
140-603 |
2.98e-62 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 222.56 E-value: 2.98e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 140 EFERDYMCNKCKHvfviKADFEQYYTFCRPSS---CPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQvqrlsvgsi 216
Cdd:PTZ00111 279 EVNEPLLCNECNS----KYTFELNHNMCVYSTkkiVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEIYMKDN--------- 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 217 pRSMKVILEDDLVDSCKSGDDLTIYGIVMQ---RWKPFQQDVRCEVEIVLKANYIQVNNEQSSGIIM------------- 280
Cdd:PTZ00111 346 -EVINLNLYDDLIDSVKTGDRVTVVGILKVtpiRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEkglkylgnendfs 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 281 DEEVQKEFEdfweyYKSDPFAGRnVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRV---------RGESHLLLV 351
Cdd:PTZ00111 425 DLQVYKILE-----LSRNPMIYR-ILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLC 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 352 GDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVT-AVKDS--GEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIH 428
Cdd:PTZ00111 499 GDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASiKFNESdnGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLY 578
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 429 EAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILE 507
Cdd:PTZ00111 579 EVMEQQTVTIAKAGIVATLKAETAILASCNPiNSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK 658
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 508 NKGYPS---------------------------KSEKLWSMEKMKTY--FCLIrNLQPTLSDVGNQVLLRYYQMQRQSD- 557
Cdd:PTZ00111 659 DFLLPHmtgsgndedtydrsntmhvedeslrseKDYNKNDLDMLRMYikFSKL-HCFPKLSDEAKKVITREYVKMRQGNf 737
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 558 ---------------------CRNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:PTZ00111 738 qtsnldelehaqedddddlyyQSSGTRMiyvSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
116-243 |
8.36e-25 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 99.86 E-value: 8.36e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 116 KTKDVGHFLSVTGTVIRTSLVK---VLEFerdYMCNKCKHVFVIKadfeqyytFCRPSSCPSlESCDS-SKFTclsgLSS 191
Cdd:pfam17207 6 RSEHIGKLVSVSGIVTRTSEVRpklKKAT---FTCRKCGHTVGVK--------ITEPTKCPN-PECGNkDPFK----LVH 69
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1807799521 192 SPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGI 243
Cdd:pfam17207 70 EKSKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGI 121
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
319-592 |
4.32e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 39.77 E-value: 4.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 319 LVKLAVAMVLAGGiqrtdatgtrvrgesHLLLVGDPGTGKSQFLKYAAK----------ITPRSVLTTGIGSTsagltvT 388
Cdd:COG0714 20 LIELVLIALLAGG---------------HLLLEGVPGVGKTTLAKALARalglpfiriqFTPDLLPSDILGTY------I 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 389 AVKDSGEWNLEAGAL----VLADaglccidefnslkEHDRTSIH------EAMEQQTISVakAGLVCKLNTRTTILAATN 458
Cdd:COG0714 79 YDQQTGEFEFRPGPLfanvLLAD-------------EINRAPPKtqsallEAMEERQVTI--PGGTYKLPEPFLVIATQN 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 459 P---KGQYDpqesvsvniaLGSPLLSRFDLILVLldtknedwdriissfilenkGYPSKSEklwsmEK---MKTYFCLIR 532
Cdd:COG0714 144 PieqEGTYP----------LPEAQLDRFLLKLYI--------------------GYPDAEE-----EReilRRHTGRHLA 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 533 NLQPTLS--------DVGNQV-----LLRY-----YQMQRQSDCRNAA--RTTIrlleSLIRLAEAHARLMFRDTVTLED 592
Cdd:COG0714 189 EVEPVLSpeellalqELVRQVhvseaVLDYivdlvRATREHPDLRKGPspRASI----ALLRAARALALLDGRDYVTPDD 264
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
305-603 |
0e+00 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 605.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 305 VILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAG 384
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 385 LTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYD 464
Cdd:cd17760 81 LTVTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 465 PQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRNLQPTLSDVGNQ 544
Cdd:cd17760 161 PNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPSKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1807799521 545 VLLRYYQMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17760 241 ILLRYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
2-605 |
1.81e-159 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 473.90 E-value: 1.81e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 2 NSDQVTLVGQVFESYVseyHKNDILLILkerdedAHYP----VVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRrsa 77
Cdd:COG1241 2 ESDLVDKFEEFLRRYK---YRDEILELA------QEYPekrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALR--- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 78 ltilQSLSQPEAVSMKQnLHARISGLPVCPELvrEHIPkTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIk 157
Cdd:COG1241 70 ----EIDLEPYDVSLGD-AHVRITNLPETVPI--RDIR-SDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYV- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 158 adfEQYYT-FCRPSSCPSlesC----------DSSKFTclsglsssptrcrDYQEIKIQEQVQRLSVGSIPRSMKVILED 226
Cdd:COG1241 141 ---PQTGEkLQEPHECPG---CgrqgpfkllpEKSEFI-------------DAQKIRIQEPPEDLPGGQQPQSIDVILED 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 227 DLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFweyyKSDPFAgRNVI 306
Cdd:COG1241 202 DLVGEVRPGDRVTVTGILRIEQRTSGRGKSTIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKEL----SKDPDI-YEKI 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 307 LASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLT 386
Cdd:COG1241 277 IASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLT 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 387 VTAVKD---SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQ 462
Cdd:COG1241 357 AAAVRDdfgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKyGR 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 463 YDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILEN--KGYPSKSEKLWSMEKMKTYfclI--------- 531
Cdd:COG1241 437 FDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVhrAGELLEQEIEEETEEVKPE---Idpdllrkyi 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 532 ----RNLQPTLSDVGNQVLLRYY-QMQRQSDCRNAART-TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQ 605
Cdd:COG1241 514 ayarRNVFPVLTEEAKDLIEDFYvDMRKKGEDEDSPVPiTARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLK 593
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
9-605 |
3.09e-151 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 452.84 E-value: 3.09e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 9 VGQVFESYVSEYHKNDILLILKERDED--AHYP--VVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRrsaltILQSL 84
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEmiAMRKrsLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALK-----EIVEE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 85 SQPEAVSMKQNLHARISGLPvcpELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYY 164
Cdd:NF040949 76 EDPEYAEEVAKFHVRFRNLP---RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESY 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 165 TFC-RPSSCPSLEScdSSKFTCLSGLSssptRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGI 243
Cdd:NF040949 153 EIVePPTVCPVCGK--PGSFRLLQEKS----KFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGI 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 244 V-MQRWKPFQQDVRCEVEIVLKANYIqvnnEQSSGIIMDEEVQKEFEDFWEYYKSDPFAgRNVILASLCPQVFGMYLVKL 322
Cdd:NF040949 227 LrIKPDSSLKKGSRPIFKNYIEANHI----EVSQKELEEVEITEEDEEKILELAKDPWI-REKIIASIAPSIYGHWEIKE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 323 AVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKD--SGEWNLEA 400
Cdd:NF040949 302 AIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDklTGEYYLEA 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 401 GALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQYDPQESVSVNIALGSPL 479
Cdd:NF040949 382 GALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKfGRYDPNRSVAENIDLPPTI 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 480 LSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIR-NLQPTLSDVGNQVLLRYY-QMQRQSD 557
Cdd:NF040949 462 LSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEKVKPEIDPDLLKKYIAYARkYVRPKLTEEAKKLIEDFYvEMRKSSK 541
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1807799521 558 CRNAART----TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQ 605
Cdd:NF040949 542 SSEDPDSpipiTARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLE 593
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
116-603 |
1.26e-143 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 427.45 E-value: 1.26e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 116 KTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVfviKADFEQYYTFCRPSSCPSlESCDS-SKFTCLSGLSsspt 194
Cdd:smart00350 9 RADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGAT---LGPEIQSGRETEPTVCPP-RECQSpTPFSLNHERS---- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 195 RCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVmqRWKPFQ-----QDVRCEVEIVLKANYIQ 269
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIY--RNVPYGfklntVKGLPVFATYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 270 VNNEQSSGIIMDEEVQK----EFEDFWEYYKSDPFAgrNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGE 345
Cdd:smart00350 159 KLDYKRSFEDSSFSVQSlsdeEEEEIRKLSKDPDIY--ERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 346 SHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHD 423
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDpeTREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 424 RTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIIS 502
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPiGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 503 SFILENKGY-----PSKSEKLWSMEKMKTYFCLIR-NLQPTLSDVGNQVLLRYY----QMQRQSDCRNAARTTIRLLESL 572
Cdd:smart00350 397 KHVVDLHRYshpeeDEAFEPPLSQEKLRKYIAYAReKIKPKLSEEAADKLVKAYvdlrKEDSQTESRSSIPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|.
gi 1807799521 573 IRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
306-603 |
1.42e-143 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 419.83 E-value: 1.42e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 306 ILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGL 385
Cdd:cd17706 2 LADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 386 TVTAVKDS--GEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQ- 462
Cdd:cd17706 82 TAAVVRDSetGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGGr 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 463 YDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFIL--------ENKGYPSKSEKLWSMEKMKTYFCLIRNL 534
Cdd:cd17706 162 YNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIdlhrgsdpEEQVKPEEDGIPIDIELLRKYILYARQI 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 535 QPTLSDVGNQVLLRYYQMQRQSDCRN-AARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17706 242 HPKISEEAREKLVRWYVELRKESERRsTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
306-603 |
2.22e-102 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 314.00 E-value: 2.22e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 306 ILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGL 385
Cdd:cd17761 3 IISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAAGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 386 TVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQ 462
Cdd:cd17761 83 TAAVVRDegTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKfGR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 463 YDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILE--NKGYPSKSEKLWSMEKMKTYFCLIR-NLQPTLS 539
Cdd:cd17761 163 FDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDthSGGEMREIKPEIDPDLLRKYIAYARkNVRPVLT 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1807799521 540 DVGNQVLLRYYQMQRQS--DCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17761 243 EEAKQLIKDFYVEMRKSgqETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIMLNC 308
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
306-603 |
2.86e-102 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 313.54 E-value: 2.86e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 306 ILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGL 385
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 386 TVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 462
Cdd:cd17757 82 TAAVVRDeeTGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPvGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 463 YDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKS-EKLWSMEKMKTYFCLIRNLQPTLSDV 541
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAiEPPFTAEQLKRYIAYARTFKPKLTKE 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1807799521 542 GNQVLLRYYQMQRQSDC----RNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17757 242 AKDELVEQYKELRQDDAsgstRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
304-508 |
7.33e-102 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 309.46 E-value: 7.33e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 304 NVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSA 383
Cdd:pfam00493 16 DKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAPRAVYTSGKGSSAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 384 GLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 460
Cdd:pfam00493 96 GLTAAVVRDpvTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLNARCSILAAANPIf 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1807799521 461 GQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILEN 508
Cdd:pfam00493 176 GRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDL 223
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
306-603 |
1.14e-94 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 294.74 E-value: 1.14e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 306 ILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGL 385
Cdd:cd17753 2 IINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 386 TVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQ 462
Cdd:cd17753 82 TASVRKDpvTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIgGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 463 YDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILEN--KGYPSKSEKLWSMEK----------------- 523
Cdd:cd17753 162 YNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGShvRSHPENDEDREGEEEknqrqrpketkvepipq 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 524 --MKTYFCLIR-NLQPTLSDVGNQVLLRYY-QMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSV 599
Cdd:cd17753 242 elLRKYIHYAReKVRPKLNQMDMDKVSRVYaDLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIRV 321
|
....
gi 1807799521 600 MESS 603
Cdd:cd17753 322 MLDS 325
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
308-603 |
2.03e-92 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 288.15 E-value: 2.03e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 308 ASLCPQVFGMYLVKLAVAMVLAGGIQRTdATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTV 387
Cdd:cd17758 4 ASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGLTA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 388 TAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQYD 464
Cdd:cd17758 83 AVMKDpvTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAyGRYN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 465 PQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFIL----ENKGYPSKSEKLwSMEKMKTYFCLIRNLQPTLS- 539
Cdd:cd17758 163 PRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTyvhqHNKQPDSDFEPL-DPKLLRAYIALAKRKRPTVPp 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1807799521 540 DVGNQVLLRYYQMQRQSDCRN-AARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17758 242 ALADYIVQAYVEMRQEAKRSKdFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
306-603 |
7.30e-91 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 284.33 E-value: 7.30e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 306 ILA-SLCPQVFGMYLVKLAVAMVLAGGIQRTDAT-GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSA 383
Cdd:cd17755 1 RLArSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 384 GLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKG 461
Cdd:cd17755 81 GLTAYVTRDpdTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 462 -QYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFI----LENKGYPSKSEkLWSMEKMKTYFCLIR-NLQ 535
Cdd:cd17755 161 sRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLvslyLEDTPEHIQDE-VLDVEVLTDYISYAReHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 536 PTLSDVGNQVLLRYYQMQRQ--SDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKmgSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
305-593 |
8.94e-84 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 266.17 E-value: 8.94e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 305 VILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAG 384
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 385 LTVTAVKDS--GEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-G 461
Cdd:cd17756 81 LTASVMRDPstREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVfG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 462 QYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILE------NKGYPSKSEKLWSMEKMKTYFCLIR-NL 534
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINihasarKASQSQENEGEIPISKLKRYIAYCRaKC 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1807799521 535 QPTLSDVGNQVLLRYY--------QMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDA 593
Cdd:cd17756 241 APRLSEEAAEKLSNHYvtirkdvrQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHV 307
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
309-600 |
4.07e-83 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 263.56 E-value: 4.07e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 309 SLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLT-- 386
Cdd:cd17754 5 SLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLTaa 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 387 VTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDP 465
Cdd:cd17754 85 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPvYGRYDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 466 QESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYpskseklwsMEKMKTYFCLIRNL-QPTLSDVGNQ 544
Cdd:cd17754 165 YKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY---------IKFLRKYIHYAKERiKPKLTQEAAE 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1807799521 545 VLLRYYQMQRQSDC--RNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVM 600
Cdd:cd17754 236 YIAEEYADLRNDDNtkTDKARTspiTARTLETLIRLATAHAKARLSKTVDKVDAEVALNLL 296
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
306-603 |
4.08e-81 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 258.23 E-value: 4.08e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 306 ILASLCPQVFGMYLVKLAVAMVLAGGIQRT--DATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSA 383
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKYadDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 384 GLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSL-KEHdrTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK 460
Cdd:cd17759 82 GLTVTLTKDgrSGDFALEAGALVLGDQGICGIDEFDKMgSQH--QALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 461 -GQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSfilenkgypskseklwSMEKMKTYFCLIR-NLQPTL 538
Cdd:cd17759 160 gGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSE----------------HHQLLRKYISYARqYVNPVL 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1807799521 539 SDVGNQVLLRYY-QMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:cd17759 224 SKDASEALQEFYlELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
140-603 |
2.98e-62 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 222.56 E-value: 2.98e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 140 EFERDYMCNKCKHvfviKADFEQYYTFCRPSS---CPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQvqrlsvgsi 216
Cdd:PTZ00111 279 EVNEPLLCNECNS----KYTFELNHNMCVYSTkkiVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEIYMKDN--------- 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 217 pRSMKVILEDDLVDSCKSGDDLTIYGIVMQ---RWKPFQQDVRCEVEIVLKANYIQVNNEQSSGIIM------------- 280
Cdd:PTZ00111 346 -EVINLNLYDDLIDSVKTGDRVTVVGILKVtpiRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEkglkylgnendfs 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 281 DEEVQKEFEdfweyYKSDPFAGRnVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRV---------RGESHLLLV 351
Cdd:PTZ00111 425 DLQVYKILE-----LSRNPMIYR-ILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLC 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 352 GDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVT-AVKDS--GEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIH 428
Cdd:PTZ00111 499 GDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASiKFNESdnGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLY 578
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 429 EAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILE 507
Cdd:PTZ00111 579 EVMEQQTVTIAKAGIVATLKAETAILASCNPiNSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK 658
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 508 NKGYPS---------------------------KSEKLWSMEKMKTY--FCLIrNLQPTLSDVGNQVLLRYYQMQRQSD- 557
Cdd:PTZ00111 659 DFLLPHmtgsgndedtydrsntmhvedeslrseKDYNKNDLDMLRMYikFSKL-HCFPKLSDEAKKVITREYVKMRQGNf 737
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 558 ---------------------CRNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESS 603
Cdd:PTZ00111 738 qtsnldelehaqedddddlyyQSSGTRMiyvSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
116-243 |
8.36e-25 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 99.86 E-value: 8.36e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 116 KTKDVGHFLSVTGTVIRTSLVK---VLEFerdYMCNKCKHVFVIKadfeqyytFCRPSSCPSlESCDS-SKFTclsgLSS 191
Cdd:pfam17207 6 RSEHIGKLVSVSGIVTRTSEVRpklKKAT---FTCRKCGHTVGVK--------ITEPTKCPN-PECGNkDPFK----LVH 69
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1807799521 192 SPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGI 243
Cdd:pfam17207 70 EKSKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGI 121
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
532-604 |
1.87e-15 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 71.81 E-value: 1.87e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1807799521 532 RNLQPTLSDVGNQVLLRYY-QM-QRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSM 604
Cdd:pfam17855 12 EKIKPKLSEEAREKLVDAYvELrKESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRLLKESL 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
347-483 |
1.15e-08 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 53.84 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 347 HLLLVGDPGTGKSQFLK-YAAKITPRSVLTTGIgstSAGLTVTAVKdsGEWNLEAGALVLADAGL---------CCIDEF 416
Cdd:pfam07728 1 GVLLVGPPGTGKTELAErLAAALSNRPVFYVQL---TRDTTEEDLF--GRRNIDPGGASWVDGPLvraaregeiAVLDEI 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1807799521 417 NSLKEHDRTSIHEAMEQQTISVAKAG-LVCKLNTRTTILAATNPkgqydPQESVSVniaLGSPLLSRF 483
Cdd:pfam07728 76 NRANPDVLNSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNP-----LDRGLNE---LSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
346-489 |
2.90e-05 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 44.44 E-value: 2.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 346 SHLLLVGDPGTGKSQFLKYAAKITPRSVLTTgIGSTSAGLTVTAVKDS--GEWNLEAGALVLADAGLCC--IDEFNSLKE 421
Cdd:cd00009 20 KNLLLYGPPGTGKTTLARAIANELFRPGAPF-LYLNASDLLEGLVVAElfGHFLVRLLFELAEKAKPGVlfIDEIDSLSR 98
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1807799521 422 HDRTSIHEAMEQQTISVakaglvcKLNTRTTILAATNPKGQYDPQEsvsvnialgsPLLSRFDLILVL 489
Cdd:cd00009 99 GAQNALLRVLETLNDLR-------IDRENVRVIGATNRPLLGDLDR----------ALYDRLDIRIVI 149
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
347-491 |
1.48e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 347 HLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLE-----------AGALVLA---DAGLCC 412
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGkkasgsgelrlRLALALArklKPDVLI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1807799521 413 IDEFNSLKEHDRtsiheAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPqesvsvnialgSPLLSRFDLILVLLD 491
Cdd:smart00382 84 LDEITSLLDAEQ-----EALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGP-----------ALLRRRFDRRIVLLL 146
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
319-592 |
4.32e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 39.77 E-value: 4.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 319 LVKLAVAMVLAGGiqrtdatgtrvrgesHLLLVGDPGTGKSQFLKYAAK----------ITPRSVLTTGIGSTsagltvT 388
Cdd:COG0714 20 LIELVLIALLAGG---------------HLLLEGVPGVGKTTLAKALARalglpfiriqFTPDLLPSDILGTY------I 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 389 AVKDSGEWNLEAGAL----VLADaglccidefnslkEHDRTSIH------EAMEQQTISVakAGLVCKLNTRTTILAATN 458
Cdd:COG0714 79 YDQQTGEFEFRPGPLfanvLLAD-------------EINRAPPKtqsallEAMEERQVTI--PGGTYKLPEPFLVIATQN 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 459 P---KGQYDpqesvsvniaLGSPLLSRFDLILVLldtknedwdriissfilenkGYPSKSEklwsmEK---MKTYFCLIR 532
Cdd:COG0714 144 PieqEGTYP----------LPEAQLDRFLLKLYI--------------------GYPDAEE-----EReilRRHTGRHLA 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 533 NLQPTLS--------DVGNQV-----LLRY-----YQMQRQSDCRNAA--RTTIrlleSLIRLAEAHARLMFRDTVTLED 592
Cdd:COG0714 189 EVEPVLSpeellalqELVRQVhvseaVLDYivdlvRATREHPDLRKGPspRASI----ALLRAARALALLDGRDYVTPDD 264
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
348-487 |
9.62e-03 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 36.80 E-value: 9.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807799521 348 LLLVGDPGTGKSQFLKYAAKITPRSVLTT---GIGSTSAGLTVTAVKDsgewnleagALVLADAGLCC---IDEFNSL-K 420
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAPFIEIsgsELVSKYVGESEKRLRE---------LFEAAKKLAPCvifIDEIDALaG 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1807799521 421 EHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPqesvsvnialgsPLLSRFDLIL 487
Cdd:pfam00004 72 SRGSGGDSESRRVVNQLLTELDGFTSSNSKVIVIAATNRPDKLDP------------ALLGRFDRII 126
|
|
| |
