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Conserved domains on  [gi|1635577162|ref|NP_001357428|]
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olfactomedin-like protein 1 isoform b [Homo sapiens]

Protein Classification

olfactomedin domain-containing protein( domain architecture ID 10490292)

olfactomedin domain-containing protein adopts a five-bladed beta-propeller structure, similar to gliomedin that interacts with neuronal cell adhesion molecules such as neurofascin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
9-259 4.57e-112

Olfactomedin-like domain;


:

Pssm-ID: 460482  Cd Length: 246  Bit Score: 322.56  E-value: 4.57e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162   9 LMGIKSLKIVKKMMDTHGSWMKDAVYNSPKVYLL-IGSRNNTVWEFANIRAFMEDNtkpAPRKQILTLSWQGTGQVIYKG 87
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTdRGTSGNTLREYASLDDFKNGS---PSKKYKLPYPWQGTGHVVYNG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162  88 FLFFHnQATSNEIIKYNLQKRTVEDRMLLPG-GVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTL 166
Cdd:pfam02191  78 SLYYN-KYNSRNIVKYDLTTRTVAARRVLPGaGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSKLDPETL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162 167 GVEHSWDTPCRSQDAEASFLLCGVLYVVYStGGQGPHRITCIYDPLgtISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYA 246
Cdd:pfam02191 157 EVEQTWNTSYPKRSAGNAFMVCGVLYAVRS-VNTRREEIFYAFDTY--TGKEEAVSIPFPNRYGKISMLDYNPRDKKLYA 233

                         250
                  ....*....|...
gi 1635577162 247 WNEGNQIIYKLQT 259
Cdd:pfam02191 234 WDDGYQVTYPVTF 246
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
9-259 4.57e-112

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 322.56  E-value: 4.57e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162   9 LMGIKSLKIVKKMMDTHGSWMKDAVYNSPKVYLL-IGSRNNTVWEFANIRAFMEDNtkpAPRKQILTLSWQGTGQVIYKG 87
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTdRGTSGNTLREYASLDDFKNGS---PSKKYKLPYPWQGTGHVVYNG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162  88 FLFFHnQATSNEIIKYNLQKRTVEDRMLLPG-GVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTL 166
Cdd:pfam02191  78 SLYYN-KYNSRNIVKYDLTTRTVAARRVLPGaGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSKLDPETL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162 167 GVEHSWDTPCRSQDAEASFLLCGVLYVVYStGGQGPHRITCIYDPLgtISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYA 246
Cdd:pfam02191 157 EVEQTWNTSYPKRSAGNAFMVCGVLYAVRS-VNTRREEIFYAFDTY--TGKEEAVSIPFPNRYGKISMLDYNPRDKKLYA 233

                         250
                  ....*....|...
gi 1635577162 247 WNEGNQIIYKLQT 259
Cdd:pfam02191 234 WDDGYQVTYPVTF 246
OLF smart00284
Olfactomedin-like domains;
26-257 1.97e-48

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 160.77  E-value: 1.97e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162   26 GSWMKDAVYNSPKVYL-----LIGSRNNTVWEFANIRAFMedNTKPaPRKQILTLSWQGTGQVIYKGFLFFhNQATSNEI 100
Cdd:smart00284  21 GAWMKDPLWNTTKKSLywympLNTRVLRSVREYSSMSDFQ--MGKN-PTDHPLPHAGQGTGVVVYNGSLYF-NKFNSHDI 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162  101 IKYNLQKRTVEDRMLLPG-GVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQ 179
Cdd:smart00284  97 CRFDLTTETYQKEPLLNGaGYNNRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVISKLNPATLTIENTWITTYNKR 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1635577162  180 DAEASFLLCGVLYVVySTGGQGPHRITCIYDPLGTISEE-DLPnlfFPKRPRSHSMIHYNPRDKQLYAWNEGNQIIYKL 257
Cdd:smart00284 177 SASNAFMICGILYVT-RSLGSKGEKVFYAYDTNTGKEGHlDIP---FENMYEYISMLDYNPNDRKLYAWNNGHLVHYDI 251
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
9-259 4.57e-112

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 322.56  E-value: 4.57e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162   9 LMGIKSLKIVKKMMDTHGSWMKDAVYNSPKVYLL-IGSRNNTVWEFANIRAFMEDNtkpAPRKQILTLSWQGTGQVIYKG 87
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTdRGTSGNTLREYASLDDFKNGS---PSKKYKLPYPWQGTGHVVYNG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162  88 FLFFHnQATSNEIIKYNLQKRTVEDRMLLPG-GVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTL 166
Cdd:pfam02191  78 SLYYN-KYNSRNIVKYDLTTRTVAARRVLPGaGYNNRFPYSWGGHTDIDLAVDENGLWVIYATEENEGNIVVSKLDPETL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162 167 GVEHSWDTPCRSQDAEASFLLCGVLYVVYStGGQGPHRITCIYDPLgtISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYA 246
Cdd:pfam02191 157 EVEQTWNTSYPKRSAGNAFMVCGVLYAVRS-VNTRREEIFYAFDTY--TGKEEAVSIPFPNRYGKISMLDYNPRDKKLYA 233

                         250
                  ....*....|...
gi 1635577162 247 WNEGNQIIYKLQT 259
Cdd:pfam02191 234 WDDGYQVTYPVTF 246
OLF smart00284
Olfactomedin-like domains;
26-257 1.97e-48

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 160.77  E-value: 1.97e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162   26 GSWMKDAVYNSPKVYL-----LIGSRNNTVWEFANIRAFMedNTKPaPRKQILTLSWQGTGQVIYKGFLFFhNQATSNEI 100
Cdd:smart00284  21 GAWMKDPLWNTTKKSLywympLNTRVLRSVREYSSMSDFQ--MGKN-PTDHPLPHAGQGTGVVVYNGSLYF-NKFNSHDI 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1635577162  101 IKYNLQKRTVEDRMLLPG-GVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQ 179
Cdd:smart00284  97 CRFDLTTETYQKEPLLNGaGYNNRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVISKLNPATLTIENTWITTYNKR 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1635577162  180 DAEASFLLCGVLYVVySTGGQGPHRITCIYDPLGTISEE-DLPnlfFPKRPRSHSMIHYNPRDKQLYAWNEGNQIIYKL 257
Cdd:smart00284 177 SASNAFMICGILYVT-RSLGSKGEKVFYAYDTNTGKEGHlDIP---FENMYEYISMLDYNPNDRKLYAWNNGHLVHYDI 251
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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